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JOURNAL ARTICLE
Tao Yu, Huiming Li, Guijia Shen, Qifang Wu
Long non-coding RNA-HEIH (lncRNA-HEIH) is a potential biomarker for patients with hepatocellular carcinoma (HCC), but exosomal lncRNA-HEIH in patients with hepatitis B virus-associated HCC (B-HCC) is unclear. This study aimed to investigate the expression of exosomal lncRNA-HEIH in B-HCC patients and explore its clinical significance. We collected blood samples from 60 B-HCC patients, 60 non-hepatitis virus-associated HCC (N-HCC) patients, and 50 healthy volunteers. Exosomal lncRNA-HEIH levels were measured by real-time PCR and analyzed for their correlation with patient prognosis using Kaplan-Meier analysis...
April 19, 2024: Annales de Biologie Clinique
#2
JOURNAL ARTICLE
Nadeem Bin Nusrat, Assad Ur Rehman, Nauman Zafar, Shujah Muhammad, Sarmad Imtiaz Bajwa, Saira Imtiaz
OBJECTIVE: To evaluate long-term outcomes in patients homogenously treated with radical cystectomy and ileal conduit for muscle invasive bladder cancer. METHODS: The retrospective study was conducted at the Urology Department of Pakistan Kidney and Liver Institute and Research Centre, Lahore, Pakistan, and comprised data from December 25, 2017, to January 16, 2023, related to patients who underwent radical cystectomy with ileal conduit with or without neo-adjuvant and adjuvant radiation, chemotherapy, or immunotherapy for papillary urothelial carcinom of the bladder...
March 2024: JPMA. the Journal of the Pakistan Medical Association
#3
JOURNAL ARTICLE
Jun Jiang, Lintao Li, Gang Yin, Huaichao Luo, Junjie Li
BACKGROUND: The incidence of breast cancer ranks highest among cancers and is exceedingly heterogeneous. Immunohistochemical staining is commonly used clinically to identify the molecular subtype for subsequent treatment and prognosis. PURPOSE: Raman spectroscopy and support vector machine (SVM) learning algorithm were utilized to identify blood samples from breast cancer patients in order to investigate a novel molecular typing approach. METHOD: Tumor tissue coarse needle aspiration biopsy samples, and peripheral venous blood samples were gathered from 459 invasive breast cancer patients admitted to the breast department of Sichuan Cancer Hospital between June 2021 and September 2022...
February 16, 2024: Clinical Breast Cancer
#4
JOURNAL ARTICLE
Claire David, Antoine Taillandier, Paul-Louis Chantreau, Rémy Kerdraon, Flore Delalande, Patrick Michenet
No abstract text is available yet for this article.
March 5, 2024: Annales de Pathologie
#5
REVIEW
P Neuville, T Murez, P H Savoie, L Rocher, A Flechon, L Ferretti, A Van Hove, N Branger, P Camparo, M Roupret
Primary urethral carcinoma (PUC) is defined as a tumor process arising within the urethra, with no history of other urinary tract localization or synchronous tumor of the urinary tract. The most common histological types are urothelial carcinoma (UC), squamous cell carcinoma (SCC) and adenocarcinoma (AC). In men, UC predominates, while AC is rare. In women, AC affects around one in two patients, while EC and UC are equally divided between the remaining cases. Diagnosis is often delayed, and requires endoscopic examination with biopsies...
March 2, 2024: Fr J Urol
#6
REVIEW
Béatrix Barry, Gilles Dolivet, Florian Clatot, Florence Huguet, Cyril Abdeddaim, Bertrand Baujat, Nicolas Blanchard, Gilles Calais, Xavier Carrat, Anne Chatellier, Florence Coste, Didier Cupissol, Philippe Cuvelier, Erwan De Mones Del Pujol, Sophie Deneuve, Olivier Duffas, Agnès Dupret-Bories, Caroline Even, Camille Evrard, Diane Evrard, Sandrine Faivre, Nicolas Fakhry, Renaud Garrel, Philippe Gorphe, Thierry Houliat, Marie-Christine Kaminsky, Lorraine Krebs, Michel Lapeyre, Pierre Lindas, Olivier Malard, Haitham Mirghani, Michel Mondina, Sylvain Moriniere, François Mouawad, Julia Pestre-Munier, Nathalie Pham Dang, Annabelle Picard, Lionel Ramin, Sophie Renard, Didier Salvan, Antoine Schernberg, Christian Sire, Juliette Thariat, Julie Vanbockstael, Dan Vo Tan, Thomas Wojcik, Isabelle Klein, Véronique Block, Lorraine Baumann-Bouscaud, Dominique De Raucourt
OBJECTIVES: The management of upper aerodigestive tract cancers is a complex specialty. It is essential to provide an update to establish optimal care. At the initiative of the INCa and under the auspices of the SFORL, the scientific committee, led by Professor Béatrix Barry, Dr. Gilles Dolivet, and Dr. Dominique De Raucourt, decided to develop a reference framework aimed at defining, in a scientific and consensus-based manner, the general principles of treatment for upper aerodigestive tract cancers applicable to all sub-locations...
February 27, 2024: Bulletin du Cancer
#7
JOURNAL ARTICLE
Charles Lépine, Aude Trinquet, Marick Laé, Valérie Costes-Martineau
In recent years, several nasal cavity and sinus entities have been described with fusion genes. Salivary gland tumors with fusion genes will not be discussed in this article, but it should be kept in mind that accessory salivary glands are present in the nasal cavity and sinuses and can therefore lead to tumoral lesions. Entities with specific or more frequently described rearrangements in the nasal cavities and sinuses are DEK::AFF2 squamous cell carcinomas,;non-intestinal and non-salivary nasosinusal adenocarcinomas, some of which displaying ETV6 gene rearrangements; biphenotypic nasosinusal sarcomas, most of which displaying PAX3 gene rearrangements; and Ewing's adamantinoma-like sarcomas, which display the same rearrangements as conventional Ewing's sarcomas, mainly the EWSR1::FLI1 rearrangement...
February 13, 2024: Annales de Pathologie
#8
M Michalet, R Tétreau, J-L Pasquié, O Chabre, D Azria
Adrenocortical carcinoma is a malignant tumor with a poor prognosis and a frequent metastatic extension. In very rare cases, a cardiac metastatic disease may occur, and surgical resection is essential for its management. MR-guided stereotactic radiotherapy is an attractive radiotherapy modality for the treatment of mobile thoracic tumors, enabling the target to be monitored continuously during irradiation, while the dosimetric plan can be adapted daily if necessary. We report here the case of a patient with intracardiac metastasis secondary to malignant adrenocortical carcinoma, treated with magnetic resonance imaging-guided stereotactic radiotherapy...
February 9, 2024: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
#9
EDITORIAL
Gilles Dolivet, Béatrix Barry, Cyril Abdeddaim, Bertrand Baujat, Nicolas Blanchard, Gilles Calais, Xavier Carrat, Anne Chatellier, Florian Clatot, Florence Coste, Didier Cupissol, Philippe Cuvelier, Erwan de Mones Del Pujol, Sophie Deneuve, Olivier Duffas, Agnès Dupret-Bories, Caroline Even, Camille Evrard, Diane Evrard, Sandrine Faivre, Nicolas Fakhry, Renaud Garrel, Phillippe Gorphe, Thierry Houliat, Florence Huguet, Marie-Christine Kaminsky, Lorraine Krebs, Michel Lapeyre, Pierre Lindas, Olivier Malard, Haitham Mirghani, Michel Mondina, Sylvain Moriniere, François Mouawad, Julia Pestre-Munier, Nathalie Pham Dang, Annabelle Picard, Lionel Ramin, Sophie Renard, Didier Salvan, Antoine Schernberg, Christian Sire, Juliette Thariat, Julie Vanbockstael, Dan Vo Tan, Thomas Wojcik, Isabelle Klein, Véronique Block, Lorraine Baumann-Bouscaud, Dominique de Raucourt
No abstract text is available yet for this article.
February 8, 2024: Bulletin du Cancer
#10
JOURNAL ARTICLE
Martin Klecka, Bruno Rodrigues, Grégoire Berthod, Niels Gobin
The most important modifiable risk factors of renal cell carcinoma are smoking, obesity and hypertension. A biopsy of the renal tumour is not always necessary. It is important in situations where it can change the therapeutic attitude and should be discussed in particular for tumors < 4 cm in size and in metastatic stage. Treatment of localized and locoregional disease consists mainly of surgical removal of the tumor. Local ablative therapy (radiofrequency, thermoablation) or active surveillance are options for small tumors < 4 cm and frail patients with high surgical risk...
February 7, 2024: Revue Médicale Suisse
#11
JOURNAL ARTICLE
Amira Hmidi, Yoldez Houcine, Salma Kamoun, Bettaib Ilhem, Aida Goucha, Maha Driss
Reverse polarity high-cell carcinoma of the breast, formerly known as reverse polarity solid papillary carcinoma, is a rare entity recently introduced into the latest edition of the WHO classification of breast tumors. Its phenotype is triple-negative, and its diagnosis difficult. Although few cases have been reported in the literature, knowledge of this breast tumor is essential to distinguish it from other triple-negative carcinomas, which have a poorer prognosis. We report a case of high-cell, inverted-polarity carcinoma of the breast in a 43-year-old female patient with no history of breast neoplasia and no palpable mass on clinical examination...
January 24, 2024: Annales de Pathologie
#12
JOURNAL ARTICLE
Monique Courtade-Saïdi
The second version of the Paris System for reporting urine cytology was published in 2022. It follows the first version of 2016, which was very successful and widely adopted by many cytopathologists from different countries. Thus, numerous publications using the Paris System have made possible to refine the criteria as well as discussing the limits. The diagnostic accuracy of urinary cytology is high for detection of high-grade urothelial carcinoma, but not for low-grade carcinoma where there are few cytological abnormalities...
January 18, 2024: Annales de Pathologie
#13
JOURNAL ARTICLE
Susie Brousse, Clémentine Lafond, Martin Schmitt, Sophie Guillermet, Sébastien Molière, Carole Mathelin
OBJECTIVES: The indications and modalities of breast and axillary surgery are undergoing profound change, with the aim of personalizing surgical management while avoiding over-treatment. To update best practices for axillary surgery, four questions were selected by the Senology Commission of the Collège National des Gynécologues et Obstétriciens Français (CNGOF), focusing on 1) the definition and evaluation of targeted axillary dissection (TAD) techniques, 2) the possibility of surgical de-escalation in case of initial lymph node involvement while performing initial surgery, 3) in case of surgery following neo-adjuvant systemic therapy (NAST), 4) contraindications to de-escalation of axillary surgery to allow access to particular adjuvant systemic therapies...
January 6, 2024: Gynecologie, Obstetrique, Fertilite & Senologie
#14
JOURNAL ARTICLE
Carole Mathelin, Susie Brousse, Martin Schmitt, Nicolas Taris, Catherine Uzan, Sébastien Molière, Charlotte Vaysse
OBJECTIVES: Breast surgery is the cornerstone of breast cancer treatment. Its indications and procedures are constantly evolving. To update best practices, four questions were submitted to the Senology Commission (SC) of the Collège National des Gynécologues et Obstétriciens Français (CNGOF), covering the indications and modalities of tumor surgery 1) initially, 2) following neoadjuvant systemic treatment, 3) in case of local recurrence, and 4) the quality and safety of care indicators applicable to this surgery...
December 18, 2023: Gynecologie, Obstetrique, Fertilite & Senologie
#15
JOURNAL ARTICLE
M Cuenin, J Salleron, D Peiffert, É Meknaci, P Gallet, Y Abushama, J-F Py, S Renard
PURPOSE: Low-dose-rate (LDR) and high-dose-rate (HDR) interstitial brachytherapy are known to be effective in the treatment of lip carcinomas. The aim of this study was to retrospectively compare oncologic and toxicity outcomes between the two techniques. PATIENTS AND METHODS: From 2007 to 2018, patients at the Institut de cancérologie de Lorraine (France) who received exclusive or adjuvant interstitial brachytherapy for lip squamous carcinomas were studied...
December 9, 2023: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
#16
JOURNAL ARTICLE
Y Ma, Q Li
PURPOSE: The purpose of this study was to develop a model for predicting chemoradiation response in non-small cell lung cancer (NSCLC) patients by integrating radiomics and deep-learning features and combined intra- and peritumoral regions with pre-treated CT images. MATERIALS AND METHODS: This study enrolled 462 patients with NSCLC who received chemoradiation. On the basis of pretreated CT images, we developed three models to compare the prediction of chemoradiation: intratumoral, peritumoral and combined regions...
November 4, 2023: Cancer Radiothérapie: Journal de la Société Française de Radiothérapie Oncologique
#17
JOURNAL ARTICLE
Emmanuelle Bourrat
Despite an increase in life expectancy and quality of life for patients suffering from severe forms of hereditary epidermolysis bullosa, the occurrence of one or more cutaneous squamous cell carcinomas remains a sometimes serious complication, sometimes life-threatening as early as adolescence. These carcinomas occur preferably on chronic wounds or dystrophic scars in areas not exposed to the sun, and are generally multifocal and recurrent. Their clinical and histological diagnosis is difficult. Regular medical and paramedical monitoring of the skin during dressing repairs enables early detection and rapid, curative surgical management...
November 2023: Soins; la Revue de Référence Infirmière
#18
JOURNAL ARTICLE
Rose Boudan, Emmanuelle Bourrat, Alia Galadari
The occurrence of cutaneous squamous cell carcinoma is a frequent and potentially serious complication in people with recessive dystrophic epidermolysis bullosa and junctional epidermolysis bullosa with chronic leg sores. Early diagnosis of early-stage carcinomas enables limited surgical excision and rapid healing without sequelae. Screening during skin care of patients at risk is therefore of major interest, and any atypical lesion should be shown to a doctor specializing in the disease and biopsied at the slightest doubt, preferably in an expert center for the disease...
November 2023: Soins; la Revue de Référence Infirmière
#19
JOURNAL ARTICLE
M Toure, M-L Quintyn-Ranty, P Saguet, R Bouchoucha, F Mouriaux, J-C Quintyn
BACKGROUND: Basal cell carcinomas (BCCs) represent 90% of malignant tumors of the eyelids, which can be locally invasive and destructive. The observation of histological safety margins (MHS) allows for the prevention of recurrence while maintaining a fair compromise between aesthetics and functionality. However, to date, there is no consensus or national recommendations concerning the MHS to be observed according to the various histological subtypes of BCCs. METHODS: Through a retrospective analysis of patient records and corresponding excisional slides, we studied the 6-year recurrence rate of 98 patients who underwent surgery for palpebral BCC...
October 20, 2023: Journal Français D'ophtalmologie
#20
JOURNAL ARTICLE
Elif Onat, Nevin Kocaman, Hilal Balta
INTRODUCTION: Colon cancer is one of the most frequent gastrointestinal system cancers on a global scale. Common colonoscopy tests have reduced the incidence of colorectal cancer (CRC). Although nutrition, microorganisms, and their metabolites are related to colon cancer, the exact mechanism of CRC is still not clear. For this reason, it is of great importance to elucidate the molecular mechanisms of colon oncogenesis. METHODS: This study was conducted retrospectively with samples obtained from the laboratory of Firat University Faculty of Medicine, Department of Pathology...
October 2023: Curēus
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