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diastolic dysfunction 2015

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https://www.readbyqxmd.com/read/27774267/the-clinical-significance-of-plasma-neopterin-in-heart-failure-with-preserved-left-ventricular-ejection-fraction
#1
Eiichiro Yamamoto, Yoshihiro Hirata, Takanori Tokitsu, Hiroaki Kusaka, Noriaki Tabata, Kenichi Tsujita, Megumi Yamamuro, Koichi Kaikita, Hiroshi Watanabe, Seiji Hokimoto, Toru Maruyama, Hisao Ogawa
AIMS: Although inflammation plays an important role in the pathogenesis of heart failure (HF), the precise pathophysiological role of inflammation in HF with preserved left ventricular ejection fraction (HFpEF) still remains unclear. Hence, we examined the clinical significance of plasma neopterin, an inflammatory biomarker, in HFpEF patients. METHODS AND RESULTS: In the present study, we recruited consecutive HFpEF patients hospitalized in Kumamoto University Hospital, and further measured plasma neopterin by high-performance liquid chromatography and serum derivatives of reactive oxidative metabolites (DROM), a new biomarker of reactive oxygen species...
March 2016: ESC Heart Failure
https://www.readbyqxmd.com/read/27761444/outcomes-of-off-pump-versus-on-pump-coronary-artery-bypass-graft-surgery-in-patients-with-severely-dilated-left-ventricle
#2
Sen Li, Wenhui Gong, Quan Qi, Zezhe Yuan, Anqing Chen, Jun Liu, Junfeng Cai, Mi Zhou, Zhe Wang, Xiaofeng Ye, Qiang Zhao
BACKGROUND: Currently, off-pump coronary artery bypass (OPCAB) grafting has been the standard procedure for surgical revascularization in patients with coronary artery disease (CAD). This study aimed to examine the safety and applicability of OPCAB compared with on-pump coronary artery bypass (ONCAB) in patients with severely dilated left ventricle. METHODS: A retrospective study of giant left ventricle patients [left ventricular end diastolic diameter (LVEDD) ≥ VE mm] undergoing coronary bypass grafting from 2009 through 2015 at a single center was conducted...
September 2016: Annals of Translational Medicine
https://www.readbyqxmd.com/read/27754071/os-18-03-greater-visit-to-visit-blood-pressure-variability-was-associated-with-cognitive-function-impairment-in-an-elderly-population-prospective-study
#3
Shao-Yuan Chuang, Hao-Ming Cheng, Bak-Sau Yip, Wen-Harn Pan, Chen-Huan Chen
OBJECTIVE: We aimed to investigate the association between visit-to-visit blood pressure variability (BPV) and future cognitive dysfunction in an elderly population. DESIGN AND METHOD: The Cardiovascular Disease Risk Factors two-Township study (CVDFACTS) was a longitudinal cohort study and the first wave survey was established during 1989-1991 and four waves of survey were carried out between 1992 and 2002. The on-going sixth wave survey was started in 2015. A total of 320 seniors aged more than 60 years participated in the sixth wave survey and received the Mini-Mental State Examination (MMSE) to evaluate the global cognitive function in 2015...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27753881/ish-ada-02-comparison-of-pulse-wave-velocity-and-pulse-pressure-amplification-in-the-association-with-target-organ-damages-in-the-community-based-elderly-the-northern-shanghai-study
#4
Bin Bai, Jin Xiong, Yuyan Lv, Shikai Yu, Jiadela Teliewubai, Chen Chi, Yiwu Zhou, Kai Wang, Le Wang, Yi Zhang, Yawei Xu
OBJECTIVE: To investigate the discrepancy between PWV and PPA in association with hypertensive TODs in the elderly population. DESIGN AND METHOD: From June 2014 to August 2015, a total of 1599 community-based elderly subjects (age > 65 years old) located in the northern Shanghai were recruited. The carotid-femoral pulse wave velocity (cfPWV), peripheral blood pressure (BP), central BP and other TODs indicators including the ratio of the early ventricular filling velocity (E) to the peak velocity of tissue Doppler velocity of septal mitral annulus (E/Ea), left ventricular mass index (LVMI), carotid intima-medium thickness (IMT), estimated glomerular filtration rate (eGFR), urinary albumin-creatinine rate (ACR) were assessed on each participant...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27748473/exercise-training-in-heart-failure-patients-with-preserved-ejection-fraction-a-systematic-review-and-meta-analysis
#5
Erick Chan, Francesco Giallauria, Carlo Vigorito, Neil A Smart
Exercise training induces physical adaptations for heart failure patients with systolic dysfunction but less is known about those patients with preserved ejection fraction. This study's aims were to establish if exercise training produces changes in peak VO2 and related measures, quality of life, general health and diastolic function in heart failure patients with preserved ejection fraction (HFpEF). We conducted a MEDLINE search (1985 to September 1, 2015), for exercise based rehabilitation trials in heart failure, using search terms 'exercise training, heart failure with preserved ejection fraction, heart failure with  normal ejection fraction, peak VO2 and diastolic heart dysfunction'...
October 14, 2016: Monaldi Archives for Chest Disease, Archivio Monaldi Per le Malattie del Torace
https://www.readbyqxmd.com/read/27680806/e5-lung-ultrasound-and-echocardiography-for-peripartum-haemodynamic-monitoring-of-patients-with-severe-preeclampsia
#6
J Ambrozic, K Prokselj, M Lucovnik
INTRODUCTION: The ability to judge intravascular volume is fundamental in the management of patients with severe preeclampsia. Insufficient intravascular volume can result in decreased oxygen delivery to tissues and exacerbates organ dysfunction. On the other hand, fluid excesses can lead to fluid extravasation and pulmonary edema. Outside of pregnancy, transthoracic echocardiography and lung ultrasonography have become important diagnostic and monitoring tools in critically ill patients...
August 2016: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/27643174/ish-ada-02-comparison-of-pulse-wave-velocity-and-pulse-pressure-amplification-in-the-association-with-target-organ-damages-in-the-community-based-elderly-the-northern-shanghai-study
#7
Bin Bai, Jin Xiong, Yuyan Lv, Shikai Yu, Jiadela Teliewubai, Chen Chi, Yiwu Zhou, Kai Wang, Le Wang, Yi Zhang, Yawei Xu
OBJECTIVE: To investigate the discrepancy between PWV and PPA in association with hypertensive TODs in the elderly population. DESIGN AND METHOD: From June 2014 to August 2015, a total of 1599 community-based elderly subjects (age > 65 years old) located in the northern Shanghai were recruited. The carotid-femoral pulse wave velocity (cfPWV), peripheral blood pressure (BP), central BP and other TODs indicators including the ratio of the early ventricular filling velocity (E) to the peak velocity of tissue Doppler velocity of septal mitral annulus (E/Ea), left ventricular mass index (LVMI), carotid intima-medium thickness (IMT), estimated glomerular filtration rate (eGFR), urinary albumin-creatinine rate (ACR) were assessed on each participant...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27642992/os-18-03-greater-visit-to-visit-blood-pressure-variability-was-associated-with-cognitive-function-impairment-in-an-elderly-population-prospective-study
#8
Shao-Yuan Chuang, Hao-Ming Cheng, Bak-Sau Yip, Wen-Harn Pan, Chen-Huan Chen
OBJECTIVE: We aimed to investigate the association between visit-to-visit blood pressure variability (BPV) and future cognitive dysfunction in an elderly population. DESIGN AND METHOD: The Cardiovascular Disease Risk Factors two-Township study (CVDFACTS) was a longitudinal cohort study and the first wave survey was established during 1989-1991 and four waves of survey were carried out between 1992 and 2002. The on-going sixth wave survey was started in 2015. A total of 320 seniors aged more than 60 years participated in the sixth wave survey and received the Mini-Mental State Examination (MMSE) to evaluate the global cognitive function in 2015...
September 2016: Journal of Hypertension
https://www.readbyqxmd.com/read/27609819/echocardiographic-structure-and-function-in-hypertensive-disorders-of-pregnancy-a-systematic-review
#9
James S Castleman, Ramesh Ganapathy, Fatima Taki, Gregory Y H Lip, Richard P Steeds, Dipak Kotecha
BACKGROUND: Echocardiography is commonly used to direct the management of hypertensive disorders in medical patients, but its application in pregnancy is unclear. Our objective was to define the use of echocardiography in pregnancies complicated by gestational hypertension (GH) and preeclampsia. METHODS AND RESULTS: We performed a systematic review of articles using an electronic search of databases from inception to March 2015, prospectively registered with PROSPERO (CRD42015015700)...
September 2016: Circulation. Cardiovascular Imaging
https://www.readbyqxmd.com/read/27437649/development-and-validation-of-risk-prediction-models-for-cardiovascular-events-in-black-adults-the-jackson-heart-study-cohort
#10
Ervin R Fox, Tandaw E Samdarshi, Solomon K Musani, Michael J Pencina, Jung Hye Sung, Alain G Bertoni, Vanessa Xanthakis, Pelbreton C Balfour, Satya S Shreenivas, Carolyn Covington, Philip R Liebson, Daniel F Sarpong, Kenneth R Butler, Thomas H Mosley, Wayne D Rosamond, Aaron R Folsom, David M Herrington, Ramachandran S Vasan, Herman A Taylor
IMPORTANCE: Cardiovascular risk assessment is a fundamental component of prevention of cardiovascular disease (CVD). However, commonly used prediction models have been formulated in primarily or exclusively white populations. Whether risk assessment in black adults is dissimilar to that in white adults is uncertain. OBJECTIVES: To develop and validate risk prediction models for CVD incidence in black adults, incorporating standard risk factors, biomarkers, and subclinical disease...
April 1, 2016: JAMA Cardiology
https://www.readbyqxmd.com/read/27390939/left-ventricular-diastolic-dysfunction-and-increased-left-ventricular-mass-index-related-to-pulmonary-hypertension-in-patients-with-systemic-autoimmune-disease-without-pericardial-effusion
#11
Atsushi Sugiura, Nobusada Funabashi, Koya Ozawa, Yoshio Kobayashi
PURPOSE: We investigated the relationship of left ventricular (LV) diastolic dysfunction and LV mass index (LVMI) against pulmonary hypertension (PH) in systemic autoimmune disease (SAD). METHODS: A total of 84 SAD patients (68 females; 53±17years; systemic lupus erythematosus, 27%; scleroderma, 17%; vasculitis, 16%; mixed connective tissue disease, 13% and polymyositis/dermatomyositis complex, 10%) without significant pericardial effusion (PE) on TTE (Vivid E9, GE) were analyzed...
October 1, 2016: International Journal of Cardiology
https://www.readbyqxmd.com/read/27390670/assessment-of-the-cardiac-autonomic-neuropathy-among-the-known-diabetics-and-age-matched-controls-using-noninvasive-cardiovascular-reflex-tests-in-a-south-indian-population-a-case-control-study
#12
Pradeep Sukla, Saurabh RamBihariLal Shrivastava, Prateek Saurabh Shrivastava, Nambaru Lakshmana Rao
AIM: Diabetes mellitus is a chronic condition characterized by hyperglycemia. The objective of the study was to estimate the prevalence of cardiac autonomic neuropathy in a rural area of South India, among the known diabetics after comparing them with the age-matched healthy controls, utilizing noninvasive cardiac autonomic neuropathy reflex tests. MATERIALS AND METHODS: A case-control study was conducted for 4 months (October 2014 to January 2015) at an Urban Health and Training Center (UHTC) of a Medical College located in Kancheepuram district, Tamil Nadu...
July 2016: Avicenna Journal of Medicine
https://www.readbyqxmd.com/read/27386773/functional-status-pulmonary-artery-pressure-and-clinical-outcomes-in-heart-failure-with-preserved-ejection-fraction
#13
Daniel Dalos, Julia Mascherbauer, Caroline Zotter-Tufaro, Franz Duca, Andreas A Kammerlander, Stefan Aschauer, Diana Bonderman
BACKGROUND: Patients with heart failure with preserved ejection fraction have functional impairment resulting in reduced quality of life. Specific pathological mechanisms underlying symptoms have not yet been defined. OBJECTIVES: The aim of this study was to identify hemodynamic and other patient-related variables that are associated with New York Heart Association (NYHA) functional class and to analyze functional class in perspective with other clinical, laboratory, imaging, and hemodynamic parameters with respect to its influence on outcomes...
July 12, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/27330742/early-detection-of-myocardial-dysfunction-in-poorly-treated-pediatric-thalassemia-children-and-adolescents-two-saudi-centers-experience
#14
Mohamed H Ibrahim, Ahmed A Azab, Naglaa M Kamal, Mostafa A Salama, Soha A Ebrahim, Ashraf M Shahin, Akram E El-Sadek, Waleid E Abdulghany, Laila M Sherief, Enas A A Abdallah
BACKGROUND & OBJECTIVE: Cardiac complications are among the most serious complications in Beta Thalassemia Major Patients. Our aim was to evaluate the value of tissue Doppler imaging (TDI) for early detection of myocardial dysfunction in pediatric and adolescent patients with B-TM before development of overt heart failure or cardiomyopathy. PATIENTS AND METHODS: 100 thalassemic patients below 18 years old and 100 healthy, age & sex matched controls were enrolled in our case-control study...
August 2016: Annals of Medicine and Surgery
https://www.readbyqxmd.com/read/27271532/differences-in-cardiovascular-manifestations-between-ankylosing-spondylitis-patients-with-and-without-kyphosis
#15
Jun Fu, Manyan Wu, Yan Liang, Kai Song, Ming Ni, Yonggang Zhang, Jiying Chen
The objective of this study is to evaluate the differences in cardiovascular manifestations between ankylosing spondylitis (AS) patients with and without kyphosis. A retrospective review of consecutive AS patients treated at our hospital between June 2013 and June 2015 was performed. There were 122 patients who met all of the inclusion and exclusion criteria. Among these patients, there were 57 (ASK group) patients with global kyphosis (GK) > 40° and 65 (AS group) patients with GK < 40°. General information, C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), electrocardiography, and echocardiography were record...
August 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27139514/evaluation-of-cardiac-functions-in-juvenile-systemic-lupus-erythematosus-with-two-dimensional-speckle-tracking-echocardiography
#16
Reyhan Dedeoglu, Sezgin Şahin, Aida Koka, Funda Öztunç, Amra Adroviç, Kenan Barut, Dicle Cengiz, Özgür Kasapçopur
The aim of this study was to investigate subclinical systolic and diastolic dysfunction in juvenile-onset systemic lupus erythematosus (j-SLE) patients with speckle tracking echocardiography (STE) and the effects of disease activity on left ventricular (LV) regional functions. Thirty-five patients with j-SLE and 30 healthy children (control group) were evaluated between January and August 2015. STE was performed on all patients and controls. Medical records, including diagnosis criteria, age at diagnosis, and duration of disease, were evaluated...
August 2016: Clinical Rheumatology
https://www.readbyqxmd.com/read/27120200/natural-history-of-cardiac-and-respiratory-involvement-prognosis-and-predictive-factors-for-long-term-survival-in-adult-patients-with-limb-girdle-muscular-dystrophies-type-2c-and-2d
#17
Abdallah Fayssoil, Adam Ogna, Cendrine Chaffaut, Sylvie Chevret, Raquel Guimarães-Costa, France Leturcq, Karim Wahbi, Helene Prigent, Frederic Lofaso, Olivier Nardi, Bernard Clair, Anthony Behin, Tanya Stojkovic, Pascal Laforet, David Orlikowski, Djillali Annane
BACKGROUND: Type 2C and 2D limb girdle muscular dystrophies (LGMD) are a group of autosomal recessive limb girdle muscular dystrophies manifested by proximal myopathy, impaired respiratory muscle function and cardiomyopathy. The correlation and the prognostic impact of respiratory and heart impairment are poorly described. We aimed to describe the long-term cardiac and respiratory follow-up of these patients and to determine predictive factors of cardio-respiratory events and mortality in LGMD 2C and 2D...
2016: PloS One
https://www.readbyqxmd.com/read/27077638/perioperative-diastolic-dysfunction-in-patients-undergoing-noncardiac-surgery-is-an-independent-risk-factor-for-cardiovascular-events-a-systematic-review-and-meta-analysis
#18
Ashraf Fayad, Mohammed T Ansari, Homer Yang, Terrence Ruddy, George A Wells
BACKGROUND: The prognostic value of perioperative diastolic dysfunction (PDD) in patients undergoing noncardiac surgery remains uncertain, and the current guidelines do not recognize PDD as a perioperative risk factor. This systematic review aimed to investigate whether existing evidence supports PDD as an independent predictor of adverse events after noncardiac surgery. METHODS: Ovid MEDLINE, PubMed, EMBASE, the Cochrane Library, and Google search engine were searched for English-language citations in April 2015 investigating PDD as a risk factor for perioperative adverse events in adult patients undergoing noncardiac surgery...
July 2016: Anesthesiology
https://www.readbyqxmd.com/read/27012401/coronary-microvascular-dysfunction-as-a-mechanism-of-angina-in-severe-as-prospective-adenosine-stress-cmr-study
#19
RANDOMIZED CONTROLLED TRIAL
Jong-Hwa Ahn, Sung Mok Kim, Sung-Ji Park, Dong Seop Jeong, Min-Ah Woo, Sin-Ho Jung, Sang-Chol Lee, Seung Woo Park, Yeon Hyeon Choe, Pyo Won Park, Jae K Oh
BACKGROUND: Although a common symptom in patients with severe aortic stenosis (AS) without obstructive coronary artery disease (CAD), little is known about the pathogenesis of exertional angina. OBJECTIVES: This study sought to prove that microvascular dysfunction is responsible for chest pain in patients with severe AS and normal epicardial coronary arteries using adenosine-stress cardiac magnetic resonance (CMR) imaging. METHODS: Between June 2012 and April 2015, 117 patients with severe AS without obstructive CAD and 20 normal controls were enrolled prospectively...
March 29, 2016: Journal of the American College of Cardiology
https://www.readbyqxmd.com/read/26984986/factors-associated-with-progression-of-right-ventricular-enlargement-and-dysfunction-after-repair-of-tetralogy-of-fallot-based-on-serial-cardiac-magnetic-resonance-imaging
#20
Yu Rim Shin, Jo Won Jung, Nam Kyun Kim, Jae Young Choi, Young Jin Kim, Hong Ju Shin, Young-Hwan Park, Han Ki Park
OBJECTIVES: Although progressive right ventricular (RV) enlargement (RVE) is common in patients with pulmonary regurgitation after tetralogy of Fallot (TOF) repair, the rate of RVE and progression of RV dysfunction varies among patients. The present study aimed to investigate the independent predictors of rapid RVE and RV dysfunction after the repair of TOF, using serial cardiac magnetic resonance imaging (MRI). METHODS: The study included consecutive patients who underwent serial cardiac MRI more than twice between January 2005 and March 2015 after the repair of TOF...
September 2016: European Journal of Cardio-thoracic Surgery
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