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Peanut Allergy

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https://www.readbyqxmd.com/read/28073703/development-of-sesame-tolerance-and-cosensitization-of-sesame-allergy-with-peanut-and-tree-nut-allergy-in-children
#1
Karen Thursday S Tuano, Kristin H Dillard, Danielle Guffey, Carla M Davis
No abstract text is available yet for this article.
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28065802/addendum-guidelines-for-the-prevention-of-peanut-allergy-in-the-united-states-report-of-the-national-institute-of-allergy-and-infectious-diseases-sponsored-expert-panel
#2
Alkis Togias, Susan F Cooper, Maria L Acebal, Amal Assa'ad, James R Baker, Lisa A Beck, Julie Block, Carol Byrd-Bredbenner, Edmond S Chan, Lawrence F Eichenfield, David M Fleischer, George J Fuchs, Glenn T Furuta, Matthew J Greenhawt, Ruchi S Gupta, Michele Habich, Stacie M Jones, Kari Keaton, Antonella Muraro, Marshall Plaut, Lanny J Rosenwasser, Daniel Rotrosen, Hugh A Sampson, Lynda C Schneider, Scott H Sicherer, Robert Sidbury, Jonathan Spergel, David R Stukus, Carina Venter, Joshua A Boyce
BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy...
December 30, 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28065278/addendum-guidelines-for-the-prevention-of-peanut-allergy-in-the-united-states-report-of-the-national-institute-of-allergy-and-infectious-diseases-sponsored-expert-panel
#3
Alkis Togias, Susan F Cooper, Maria L Acebal, Amal Assa'ad, James R Baker, Lisa A Beck, Julie Block, Carol Byrd-Bredbenner, Edmond S Chan, Lawrence F Eichenfield, David M Fleischer, George J Fuchs, Glenn T Furuta, Matthew J Greenhawt, Ruchi S Gupta, Michele Habich, Stacie M Jones, Kari Keaton, Antonella Muraro, Marshall Plaut, Lanny J Rosenwasser, Daniel Rotrosen, Hugh A Sampson, Lynda C Schneider, Scott H Sicherer, Robert Sidbury, Jonathan Spergel, David R Stukus, Carina Venter, Joshua A Boyce
BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy...
January 2017: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/28054723/addendum-guidelines-for-the-prevention-of-peanut-allergy-in-the-united-states-report-of-the-national-institute-of-allergy-and-infectious-diseases-sponsored-expert-panel
#4
Alkis Togias, Susan F Cooper, Maria L Acebal, Amal Assa'ad, James R Baker, Lisa A Beck, Julie Block, Carol Byrd-Bredbenner, Edmond S Chan, Lawrence F Eichenfield, David M Fleischer, George J Fuchs, Glenn T Furuta, Matthew J Greenhawt, Ruchi S Gupta, Michele Habich, Stacie M Jones, Kari Keaton, Antonella Muraro, Marshall Plaut, Lanny J Rosenwasser, Daniel Rotrosen, Hugh A Sampson, Lynda C Schneider, Scott H Sicherer, Robert Sidbury, Jonathan Spergel, David R Stukus, Carina Venter, Joshua A Boyce
BACKGROUND: Food allergy is an important public health problem because it affects children and adults, can be severe and even life-threatening, and may be increasing in prevalence. Beginning in 2008, the National Institute of Allergy and Infectious Diseases, working with other organizations and advocacy groups, led the development of the first clinical guidelines for the diagnosis and management of food allergy. A recent landmark clinical trial and other emerging data suggest that peanut allergy can be prevented through introduction of peanut-containing foods beginning in infancy...
January 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28054718/addendum-guidelines-for-the-prevention-of-peanut-allergy-in-the-united-states-summary-of-the-national-institute-of-allergy-and-infectious-diseases-sponsored-expert-panel
#5
Alkis Togias, Susan F Cooper, Maria L Acebal, Amal Assa'ad, James R Baker, Lisa A Beck, Julie Block, Carol Byrd-Bredbenner, Edmond S Chan, Lawrence F Eichenfield, David M Fleischer, George J Fuchs, Glenn T Furuta, Matthew J Greenhawt, Ruchi S Gupta, Michele Habich, Stacie M Jones, Kari Keaton, Antonella Muraro, Marshall Plaut, Lanny J Rosenwasser, Daniel Rotrosen, Hugh A Sampson, Lynda C Schneider, Scott H Sicherer, Robert Sidbury, Jonathan Spergel, David R Stukus, Carina Venter, Joshua A Boyce
No abstract text is available yet for this article.
January 2017: Pediatric Dermatology
https://www.readbyqxmd.com/read/28049187/enhanced-prophylactic-and-therapeutic-effects-of-polylysine-modified-ara-h-2-dna-vaccine-in-a-mouse-model-of-peanut-allergy
#6
Zhenlai Zhu, Jinlei Yu, Yuan Niu, Shuhong Sun, Yufeng Liu, Andrew Saxon, Ke Zhang, Wei Li
BACKGROUND: The prevalence of food allergy has been increasing, but treatment is very limited. DNA vaccination has been recognized as a promising method for the treatment of allergic diseases; however, poor immunogenicity has hindered its application. METHODS: BALB/c mice were intradermally injected with plasmid DNA encoding the peanut protein Ara h 2 (pAra h 2) or pAra h 2 pretreated with poly-L- lysine (PLL) before or after sensitization with Ara h 2 protein. Ara h 2-specific antibodies were measured by ELISA...
January 4, 2017: International Archives of Allergy and Immunology
https://www.readbyqxmd.com/read/28042528/desensitization-for-peanut-allergies-in-children
#7
Rekha D Jhamnani, Pamela Frischmeyer-Guerrerio
Immunotherapy for peanut allergy has been an exploding topic of study within the last few years. Sublingual, epicutaneous, and oral immunotherapy are being investigated and show promise in the treatment of peanut allergy. Oral immunotherapy has shown the most clinical benefit; however, sublingual and epicutaneous immunotherapy appear to have the most favorable safety profiles. Most studies to date suggest that only a minority of subjects achieve sustained unresponsiveness to peanut after discontinuation of immunotherapy...
September 2016: Current Treatment Options in Allergy
https://www.readbyqxmd.com/read/28039897/early-introduction-of-food-reduces-food-allergy-pro
#8
Debra J Palmer, Susan L Prescott
Over the past two decades we have been debating the question of whether the age of commencement of complementary feeding affects the risk of developing food allergy. We ate up the notion that delayed introduction of more allergenic foods in early childhood, would help overcome the increasing rates of food allergy, then we promptly spat it out again despite limited evidence. Recently high-quality randomised controlled trial evidence has given us the confidence to swallow the concept that allergenic foods, like egg and peanut, should be given to infants...
December 31, 2016: Pediatric Allergy and Immunology
https://www.readbyqxmd.com/read/28030748/guidelines-for-children-with-peanut-allergy
#9
Megan A Moreno
No abstract text is available yet for this article.
January 1, 2017: JAMA Pediatrics
https://www.readbyqxmd.com/read/28027215/complementary-feeding-a-position-paper-by-the-european-society-for-paediatric-gastroenterology-hepatology-and-nutrition-espghan-committee-on-nutrition
#10
Mary Fewtrell, Jiri Bronsky, Cristina Campoy, Magnus Domellöf, Nicholas Embleton, Nataša Fidler Mis, Iva Hojsak, Jessie M Hulst, Flavia Indrio, Alexandre Lapillonne, Christian Molgaard
: This position paper considers different aspects of complementary feeding (CF), focussing on healthy term infants in Europe. After reviewing current knowledge and practices, we have formulated these recommendations: Timing: Exclusive or full breast-feeding should be promoted for at least 4 months (17 weeks, beginning of the 5th month of life) and exclusive or predominant breast-feeding for approximately 6 months (26 weeks, beginning of the 7th month) is a desirable goal. Complementary foods (solids and liquids other than breast milk or infant formula) should not be introduced before 4 months but should not be delayed beyond 6 months...
January 2017: Journal of Pediatric Gastroenterology and Nutrition
https://www.readbyqxmd.com/read/28007089/epidemiology-of-anaphylaxis-at-a-tertiary-care-center-a-report-of-730-cases
#11
Alexei Gonzalez-Estrada, Stacy K Silvers, Asaf Klein, Katrina Zell, Xiao-Feng Wang, David M Lang
BACKGROUND: Recent data reveal that the rate of anaphylaxis is increasing and suggest that idiopathic anaphylaxis may account for most of these cases. OBJECTIVE: To determine the pattern of anaphylaxis at a tertiary care referral center. METHODS: A retrospective electronic medical record review spanning 12 years (2002-2013) identified patients with anaphylaxis. RESULTS: Of the 4,777 records reviewed, 730 patients met our anaphylaxis definition...
January 2017: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/28000310/peanut-allergy-as-a-family-project-social-relations-and-transitions-in-adolescence
#12
A Stensgaard, C Bindslev-Jensen, D Nielsen
AIMS AND OBJECTIVE: to explore and better understand the impact that peanut allergy can have on family experiences in everyday life through interviews with individual family members. BACKGROUND: Peanut allergy affects adolescents' quality of life through the need to avoid eating peanut-containing food and the risk of anaphylaxis. Adolescence is a period of increasing separation from parents and has the highest risk of food fatalities. DESIGN: A qualitative interview study taking a phenomenological-hermeneutic approach...
December 21, 2016: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/27986372/withdrawn-introduction-to-the-addendum-guidelines-for-the-prevention-of-peanut-allergy-in-the-united-states
#13
Michele M Habich
The publisher regrets that this article has been temporarily removed. A replacement will appear as soon as possible in which the reason for the removal of the article will be specified, or the article will be reinstated. The full Elsevier Policy on Article Withdrawal can be found at http://www.elsevier.com/locate/withdrawalpolicy.
December 13, 2016: Journal of Pediatric Nursing
https://www.readbyqxmd.com/read/27979211/peanut-protein-extraction-conditions-strongly-influence-yield-of-allergens-ara-h-1-and-2-and-sensitivity-of-immunoassays
#14
Nicole E Walczyk, Penelope M C Smith, Euan R Tovey, Thomas H Roberts
The clinical importance of peanut (Arachis hypogaea) allergies demands standardized allergen extraction protocols. We determined the effectiveness of common extraction conditions (20 buffers, defatting reagents, extraction time/temperatures, processing, extraction repeats) on crude protein and Ara h 1 and 2 yields. Despite similar 1D-gel profiles, defatting with n-hexane resulted in significantly higher yields of crude protein, Ara h 1, and Ara h 2 than with diethyl ether. The yields were affected by the composition and pH of the extraction buffers and other conditions, but crude protein yield did not always correlate with Ara h 1 and 2 yields...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27976436/quality-of-life-in-childhood-adolescence-and-adult-food-allergy-patient-and-parent-perspectives
#15
A Stensgaard, C Bindslev-Jensen, D Nielsen, M Munch, A DunnGalvin
BACKGROUND: Studies of children with food allergy typically only include the mother and have not investigated the relationship between the amount of allergen needed to elicit a clinical reaction (threshold) and health-related quality of life (HRQL). Our aims were (i) to compare self-reported and parent-reported HRQL in different age groups, (ii) to evaluate the impact of severity of allergic reaction and threshold on HRQL, and (iii) to investigate factors associated with patient-reported and parent-reported HRQL...
November 5, 2016: Clinical and Experimental Allergy: Journal of the British Society for Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27957697/benefit-of-slit-and-scit-for-allergic-rhinitis-and-asthma
#16
REVIEW
Giovanni Passalacqua, Giorgio Walter Canonica, Diego Bagnasco
Allergen immunotherapy (AIT) has been in use since more than one century, when Leonard Noon experimentally proved its efficacy in hayfever (Noon, in Lancet 1:1572-3, 1911). Since then, AIT was administered only as subcutaneous injections (SCIT) until the sublingual route (SLIT) was proposed in 1986. The use of SLIT was proposed following several surveys from the USA and UK that repeatedly reported fatalities due to SCIT (Lockey et al. in J Allergy Clin Immunol 75(1): 166, 1985; Lockey et al. in J Allergy Clin Immunol 660-77, 1985; Committee on the safety of medicines...
November 2016: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/27942502/utility-of-specific-ige-to-ara-h-2-in-italian-allergic-and-tolerant-children-sensitized-to-peanut
#17
Pasquale Comberiati, Laura Colavita, Federica Minniti, Giulia Paiola, Carlo Capristo, Cristoforo Incorvaia, Diego Giampiero Peroni
Emerging data suggest that measurement of serum IgE to peanut components can be clinically helpful and more accurate than IgE to whole peanut to predict peanut allergy. Not all studies have used prospective samples, multiple components and oral challenges. Currently, there are no data on this topic involving Italian children. 32 patients (23 males; median age 9 years) with reported history for peanut allergy and evidence of peanut sensitization (skin prick test to peanut extract ≥ 3mm) have been analyzed for serum IgE to whole peanut and recombinant allergen components Ara h 1, 2, 3, 8, and 9 with Immuno CAP and completed an open oral food challenge with peanut...
2016: International Journal of Molecular and Cellular Medicine
https://www.readbyqxmd.com/read/27931535/advances-in-food-allergy-in-2015
#18
REVIEW
Robert A Wood
This review highlights research advances in food allergy that were published in the Journal in 2015. The world of food allergy research continues to rapidly accelerate, with increasing numbers of outstanding submissions to the Journal. In 2015, important studies on the epidemiology of food allergy were published, suggesting differential rates of food allergy in specific racial and ethnic groups. Even more importantly, studies were published identifying specific risk factors for the development of peanut allergy, as well as specific prevention strategies...
December 2016: Journal of Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27931280/safety-profile-of-oral-immunotherapy-with-cows-milk-and-hen-egg-a-10-year-experience-in-controlled-trials
#19
Giovanni B Pajno, Lucia Caminiti, Fernanda Chiera, Giuseppe Crisafulli, Giuseppina Salzano, Stefania Arasi, Giovanni Passalacqua
BACKGROUND: Oral immunotherapy (OIT) for food allergy is gaining interest due to the favorable clinical results reported with cow's milk, hen egg and peanut. The safety of the procedure remains a critical aspect that can limit the introduction of OIT in clinical practice. OBJECTIVE: We described herein, in detail, the occurrence and characteristics of adverse events (AE) with OIT in children who participated in controlled trials at our unit. METHODS: The clinical records of 68 children who received active treatment (40 for cow's milk and 28 for hen egg) were carefully reviewed...
September 2016: Allergy and Asthma Proceedings:
https://www.readbyqxmd.com/read/27896827/leaping-through-the-looking-glass-secondary-analysis-of-the-effect-of-skin-test-size-and-age-of-introduction-on-peanut-tolerance-after-early-peanut-introduction
#20
Matthew Greenhawt, David Fleischer, Edmond S Chan, Carina Venter, David Stukus, Ruchi Gupta, Jonathan Spergel
BACKGROUND: In the Learning Early About Peanut Allergy (LEAP) study, early peanut introduction in high-risk 4-11 month olds was associated with a significantly decreased risk of developing peanut allergy. However, the influences of key baseline high-risk factors on peanut tolerance are poorly understood. METHODS: Secondary analysis was conducted on the publically available LEAP dataset, exploring relationships between peanut tolerance, baseline peanut/egg sensitization, eczema severity/duration, age of introduction, gender, and race...
November 29, 2016: Allergy
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