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Todd Anderson

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https://www.readbyqxmd.com/read/28525540/alcohol-consumption-and-common-carotid-intima-media-thickness-the-use-imt-study
#1
Annie R Britton, Diederick E Grobbee, Hester M den Ruijter, Todd J Anderson, Moise Desvarieux, Gunnar Engström, Greg W Evans, Bo Hedblad, Jussi Kauhanen, Sudhir Kurl, Eva M Lonn, Ellisiv B Mathiesen, Joseph F Polak, Jacqueline F Price, Christopher M Rembold, Maria Rosvall, Tatjana Rundek, Jukka T Salonen, Coen Stehouwer, Tomi-Pekka Tuomainen, Michiel L Bots
Aims: Epidemiological evidence indicates a protective effect of light to moderate alcohol consumption compared to non-drinking and heavy drinking. Although several mechanisms have been suggested, the effect of alcohol on atherosclerotic changes in vessel walls is unclear. Therefore, we explored the relationship between alcohol consumption and common carotid intima media thickness, a marker of early atherosclerosis in the general population. Methods: Individual participant data from eight cohorts, involving 37,494 individuals from the USE-IMT collaboration were used...
May 19, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
https://www.readbyqxmd.com/read/28524792/analysis-and-interrater-reliability-of-pb-c2-using-mri-and-ct-data-from-the-park-reeves-syringomyelia-research-consortium-on-behalf-of-the-pediatric-craniocervical-society
#2
Todd C Hankinson, Gerald F Tuite, Dagmara I Moscoso, Leslie C Robinson, James C Torner, David D Limbrick, Tae Sung Park, Richard C E Anderson
OBJECTIVE The distance to the ventral dura, perpendicular to the basion to C2 line (pB-C2), is commonly employed as a measure describing the anatomy of the craniovertebral junction. However, both the reliability among observers and the clinical utility of this measurement in the context of Chiari malformation Type I (CM-I) have been incompletely determined. METHODS Data were reviewed from the first 600 patients enrolled in the Park-Reeves Syringomyelia Research Consortium with CM-I and syringomyelia. Thirty-one cases were identified in which both CT and MRI studies were available for review...
May 19, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28494054/conservative-treatment-of-isolated-cricoid-cartilage-fractures-from-blunt-trauma
#3
Todd E Falcone, Marissa A Schwartz, Annie S Lee, Timothy D Anderson
No abstract text is available yet for this article.
May 11, 2017: JAMA Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28449839/statin-prescriptions-for-high-risk-patients-are-increased-by-laboratory-initiated-framingham-risk-scores-a-quality-improvement-initiative
#4
Christopher Naugler, Charles Cook, Louise Morrin, James Wesenberg, Allison A Venner, Norman Campbell, Todd Anderson
Low rates of cardiovascular preventive therapy with statin medications is a significant public health problem in Canada. There is a pressing need for public health interventions to increase the use of statin medications, especially among high-risk patients. In this article, we present the results of a quality assurance pilot program to provide laboratory-reported Framingham Risk Score (FRS) to physicians. This work was performed in a mixed urban and rural setting in southern Alberta. We provided FRSs and, for high-risk patients, statin treatment recommendations in conjunction with laboratory lipid panel requests...
May 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28440932/microplastics-in-a-freshwater-environment-receiving-treated-wastewater-effluent
#5
Steven Lasee, Jessica Mauricio, William A Thompson, Adcharee Karnjanapiboonwong, John Kasumba, Seenivasan Subbiah, Audra N Morse, Todd A Anderson
Small plastic fragments (microplastics or solid particles <5 mm in size or "microbeads" used in personal care products and cosmetics) may ultimately find their way into aquatic environments. We studied the presence of microplastics (particle sizes 53-105 μm and 106-179 μm) spatially and temporally in 3 connected urban lakes being fed by treated wastewater effluent in Lubbock, Texas. These lakes also serve as drainage during storm events. Water samples from drainage playa wetlands within the city were also collected...
May 2017: Integrated Environmental Assessment and Management
https://www.readbyqxmd.com/read/28434648/nivolumab-in-patients-with-advanced-hepatocellular-carcinoma-checkmate-040-an-open-label-non-comparative-phase-1-2-dose-escalation-and-expansion-trial
#6
Anthony B El-Khoueiry, Bruno Sangro, Thomas Yau, Todd S Crocenzi, Masatoshi Kudo, Chiun Hsu, Tae-You Kim, Su-Pin Choo, Jörg Trojan, Theodore H Welling, Tim Meyer, Yoon-Koo Kang, Winnie Yeo, Akhil Chopra, Jeffrey Anderson, Christine Dela Cruz, Lixin Lang, Jaclyn Neely, Hao Tang, Homa B Dastani, Ignacio Melero
BACKGROUND: For patients with advanced hepatocellular carcinoma, sorafenib is the only approved drug worldwide, and outcomes remain poor. We aimed to assess the safety and efficacy of nivolumab, a programmed cell death protein-1 (PD-1) immune checkpoint inhibitor, in patients with advanced hepatocellular carcinoma with or without chronic viral hepatitis. METHODS: We did a phase 1/2, open-label, non-comparative, dose escalation and expansion trial (CheckMate 040) of nivolumab in adults (≥18 years) with histologically confirmed advanced hepatocellular carcinoma with or without hepatitis C or B (HCV or HBV) infection...
April 20, 2017: Lancet
https://www.readbyqxmd.com/read/28430052/predicting-complication-risk-in-spine-surgery-a-prospective-analysis-of-a-novel-risk-assessment-tool
#7
Anand Veeravagu, Amy Li, Christian Swinney, Lu Tian, Adrienne Moraff, Tej D Azad, Ivan Cheng, Todd Alamin, Serena S Hu, Robert L Anderson, Lawrence Shuer, Atman Desai, Jon Park, Richard A Olshen, John K Ratliff
OBJECTIVE The ability to assess the risk of adverse events based on known patient factors and comorbidities would provide more effective preoperative risk stratification. Present risk assessment in spine surgery is limited. An adverse event prediction tool was developed to predict the risk of complications after spine surgery and tested on a prospective patient cohort. METHODS The spinal Risk Assessment Tool (RAT), a novel instrument for the assessment of risk for patients undergoing spine surgery that was developed based on an administrative claims database, was prospectively applied to 246 patients undergoing 257 spinal procedures over a 3-month period...
April 21, 2017: Journal of Neurosurgery. Spine
https://www.readbyqxmd.com/read/28419414/association-between-aggressive-care-and-bereaved-families-evaluation-of-end-of-life-care-for-veterans-with-non-small-cell-lung-cancer-who-died-in-veterans-affairs-facilities
#8
Mary Ersek, Susan C Miller, Todd H Wagner, Joshua M Thorpe, Dawn Smith, Cari R Levy, Risha Gidwani, Katherine Faricy-Anderson, Karl A Lorenz, Bruce Kinosian, Vincent Mor
BACKGROUND: To the authors' knowledge, little is known regarding the relationship between patients' and families' satisfaction with aggressive end-of-life care. Herein, the authors examined the associations between episodes of aggressive care (ie, chemotherapy, mechanical ventilation, acute hospitalizations, and intensive care unit admissions) within the last 30 days of life and families' evaluations of end-of-life care among patients with non-small cell lung cancer (NSCLC). METHODS: A total of 847 patients with NSCLC (34% of whom were aged <65 years) who died in a nursing home or intensive care, acute care, or hospice/palliative care (HPC) unit at 1 of 128 Veterans Affairs Medical Centers between 2010 and 2012 were examined...
April 17, 2017: Cancer
https://www.readbyqxmd.com/read/28399495/stable-isotopic-composition-of-perchlorate-and-nitrate-accumulated-in-plants-hydroponic-experiments-and-field-data
#9
Nubia Luz Estrada, J K Böhlke, Neil C Sturchio, Baohua Gu, Greg Harvey, Kent O Burkey, David A Grantz, Margaret T McGrath, Todd A Anderson, Balaji Rao, Ritesh Sevanthi, Paul B Hatzinger, W Andrew Jackson
Natural perchlorate (ClO4(-)) in soil and groundwater exhibits a wide range in stable isotopic compositions (δ(37)Cl, δ(18)O, and Δ(17)O), indicating that ClO4(-) may be formed through more than one pathway and/or undergoes post-depositional isotopic alteration. Plants are known to accumulate ClO4(-), but little is known about their ability to alter its isotopic composition. We examined the potential for plants to alter the isotopic composition of ClO4(-) in hydroponic and field experiments conducted with snap beans (Phaseolus vulgaris L...
October 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28388333/blunted-myoglobin-and-quadriceps-soreness-after-electrical-stimulation-during-the-luteal-phase-or-oral-contraception
#10
Lindsey J Anderson, Lucinda L Baker, E Todd Schroeder
PURPOSE: Acute muscle damage after exercise triggers subsequent regeneration, leading to hypertrophy and increased strength after repeated exercise. It has been debated whether acute exercise-induced muscle damage is altered under various premenopausal estrogen conditions. Acute contraction-induced muscle damage was compared during exogenous (oral contraceptive, OC), endogenous (luteal phase, HI), or low (menses, LO) estrogen in healthy young women aged 21 to 30 years old. METHODS: Women (OC, n = 9; HI, n = 9; LO, n = 8; total N = 26) performed 1 neuromuscular electrical stimulation (NMES) bout...
June 2017: Research Quarterly for Exercise and Sport
https://www.readbyqxmd.com/read/28374318/erratum-to-systematic-verification-of-bioanalytical-similarity-between-a-biosimilar-and-a-reference-biotherapeutic-committee-recommendations-for-the-development-and-validation-of-a-single-ligand-binding-assay-to-support-pharmacokinetic-assessments
#11
Joseph C Marini, Michael Anderson, Xiao-Yan Cai, John Chappell, Todd Coffey, Dominique Gouty, Aparna Kasinath, Vera Koppenburg, Philip Oldfield, Shannon Rebarchak, Ronald R Bowsher
No abstract text is available yet for this article.
April 3, 2017: AAPS Journal
https://www.readbyqxmd.com/read/28323823/clustering-of-cardiovascular-risk-factors-and-carotid-intima-media-thickness-the-use-imt-study
#12
Xin Wang, Geertje W Dalmeijer, Hester M den Ruijter, Todd J Anderson, Annie R Britton, Jacqueline Dekker, Gunnar Engström, Greg W Evans, Jacqueline de Graaf, Diederick E Grobbee, Bo Hedblad, Suzanne Holewijn, Ai Ikeda, Jussi Kauhanen, Kazuo Kitagawa, Akihiko Kitamura, Sudhir Kurl, Eva M Lonn, Matthias W Lorenz, Ellisiv B Mathiesen, Giel Nijpels, Shuhei Okazaki, Joseph F Polak, Jacqueline F Price, Christopher M Rembold, Maria Rosvall, Tatjana Rundek, Jukka T Salonen, Matthias Sitzer, Coen D A Stehouwer, Tomi-Pekka Tuomainen, Sanne A E Peters, Michiel L Bots
BACKGROUND: The relation of a single risk factor with atherosclerosis is established. Clinically we know of risk factor clustering within individuals. Yet, studies into the magnitude of the relation of risk factor clusters with atherosclerosis are limited. Here, we assessed that relation. METHODS: Individual participant data from 14 cohorts, involving 59,025 individuals were used in this cross-sectional analysis. We made 15 clusters of four risk factors (current smoking, overweight, elevated blood pressure, elevated total cholesterol)...
2017: PloS One
https://www.readbyqxmd.com/read/28316146/cover-image-volume-118-number-5-may-2017
#13
Lipsa Das, Todd A Anderson, Jaime M C Gard, Isis C Sroka, Stephanie R Strautman, Raymond B Nagle, Colm Morrissey, Beatrice S Knudsen, Anne E Cress
Cover: The cover image, by Anne E. Cress., is based on the Article Characterization of Laminin Binding Integrin Internalization in Prostate Cancer Cells, DOI: 10.1002/jcb.25673.
May 2017: Journal of Cellular Biochemistry
https://www.readbyqxmd.com/read/28279371/carotid-plaque-lipid-content-and-fibrous-cap-status-predict-systemic-cv-outcomes-the-mri-substudy-in-aim-high
#14
Jie Sun, Xue-Qiao Zhao, Niranjan Balu, Moni B Neradilek, Daniel A Isquith, Kiyofumi Yamada, Gádor Cantón, John R Crouse, Todd J Anderson, John Huston, Kevin O'Brien, Daniel S Hippe, Nayak L Polissar, Chun Yuan, Thomas S Hatsukami
OBJECTIVES: The aim of this study was to investigate whether and what carotid plaque characteristics predict systemic cardiovascular outcomes in patients with clinically established atherosclerotic disease. BACKGROUND: Advancements in atherosclerosis imaging have allowed assessment of various plaque characteristics, some of which are more directly linked to the pathogenesis of acute cardiovascular events compared to plaque burden. METHODS: As part of the event-driven clinical trial AIM-HIGH (Atherothrombosis Intervention in Metabolic Syndrome with Low HDL/High Triglycerides: Impact on Global Health Outcomes), subjects with clinically established atherosclerotic disease underwent multicontrast carotid magnetic resonance imaging (MRI) to detect plaque tissue composition and high-risk features...
March 2017: JACC. Cardiovascular Imaging
https://www.readbyqxmd.com/read/28275196/mutating-the-cx3c-motif-in-the-g-protein-should-make-a-live-respiratory-syncytial-virus-vaccine-safer-and-more-effective
#15
S Boyoglu-Barnum, S O Todd, J Meng, T R Barnum, T Chirkova, L M Haynes, S J Jadhao, R A Tripp, A G Oomens, M L Moore, L J Anderson
Respiratory syncytial virus (RSV) belongs to the family Paramyxoviridae and is the single most important cause of serious lower respiratory tract infections in young children, yet no highly effective treatment or vaccine is available. Through a CX3C chemokine motif ((182)CWAIC(186)) in the G protein, RSV binds to the corresponding chemokine receptor, CX3CR1. Since RSV binding to CX3CR1 contributes to disease pathogenesis, we investigated whether a mutation in the CX3C motif by insertion of an alanine, A(186), within the CX3C motif, mutating it to CX4C ((182)CWAIAC(187)), which is known to block binding to CX3CR1, might decrease disease...
May 15, 2017: Journal of Virology
https://www.readbyqxmd.com/read/28204979/one-year-swallowing-outcomes-in-patients-treated-with-prophylactic-gabapentin-during-radiation-based-treatment-for-oropharyngeal-cancer
#16
Heather M Starmer, WuYang Yang, Christine G Gourin, Rachit Kumar, Bronwyn Jones, Todd McNutt, Sierra Cheng, Harry Quon
Recent investigations by our study team have demonstrated patients using gabapentin for pain management during chemoradiotherapy (CRT) do well maintaining swallowing during treatment with less need for narcotic pain medication, PEG dependence, weight loss, and short-term swallowing morbidity. The purpose of this investigation was to characterize the long-term swallowing function of these patients 1-year following treatment. Sequential patients receiving CRT for oropharyngeal cancer and concurrent gabapentin were evaluated 1-year following treatment for swallowing outcomes...
June 2017: Dysphagia
https://www.readbyqxmd.com/read/28107724/effect-of-sole-or-combined-administration-of-nitrate-and-3-nitro-1-propionic-acid-on-fermentation-and-salmonella-survivability-in-alfalfa-fed-rumen-cultures-in-vitro
#17
Alejandro Castañeda Correa, Julian Trachsel, Heather K Allen, Agustin Corral-Luna, Hector Gutierrez-Bañuelos, Pedro Antonia Ochoa-Garcia, Oscar Ruiz-Barrera, Michael E Hume, Todd R Callaway, Roger B Harvey, Ross C Beier, Robin C Anderson, David J Nisbet
Ruminal methanogenesis is a digestive inefficiency resulting in the loss of dietary energy consumed by the host and contributing to environmental methane emission. Nitrate is being investigated as a feed supplement to reduce rumen methane emissions but safety and efficacy concerns persist. To assess potential synergies of co-administering sub-toxic amounts of nitrate and 3-nitro-1-propionate (NPA) on fermentation and Salmonella survivability with an alfalfa-based diet, ruminal microbes were cultured with additions of 8 or 16mM nitrate, 4 or 12mM NPA or their combinations...
April 2017: Bioresource Technology
https://www.readbyqxmd.com/read/28056003/notes-from-the-field-botulism-outbreak-from-drinking-prison-made-illicit-alcohol-in-a-federal-correctional-facility-mississippi-june-2016
#18
Lindsey McCrickard, Mariel Marlow, Julie L Self, Louise Francois Watkins, Kevin Chatham-Stephens, Jannifer Anderson, Sheryl Hand, Kathryn Taylor, Jennifer Hanson, Keiundria Patrick, Carolina Luquez, Janet Dykes, Suzanne R Kalb, Kaitlin Hoyt, John R Barr, Todd Crawford, Anthony Chambers, Brian Douthit, Robert Cox, Matt Craig, John Spurzem, Joseph Doherty, Michael Allswede, Paul Byers, Thomas Dobbs
No abstract text is available yet for this article.
January 6, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28051805/%C3%A2-metastatic-lymphoepithelioma-like-hepatocellular-carcinoma-a-potential-diagnostic-pitfall-and-demonstration-of-pd-l1-expression
#19
Juan Putra, Todd A Anderson, Sasan Roayaie, Miho Maeda, Swan N Thung
No abstract text is available yet for this article.
January 2017: Annals of Hepatology
https://www.readbyqxmd.com/read/28049818/impact-of-short-chain-galactooligosaccharides-on-the-gut-microbiome-of-lactose-intolerant-individuals
#20
M Andrea Azcarate-Peril, Andrew J Ritter, Dennis Savaiano, Andrea Monteagudo-Mera, Carlton Anderson, Scott T Magness, Todd R Klaenhammer
Directed modulation of the colonic bacteria to metabolize lactose effectively is a potentially useful approach to improve lactose digestion and tolerance. A randomized, double-blind, multisite placebo-controlled trial conducted in human subjects demonstrated that administration of a highly purified (>95%) short-chain galactooligosaccharide (GOS), designated "RP-G28," significantly improved clinical outcomes for lactose digestion and tolerance. In these individuals, stool samples were collected pretreatment (day 0), after GOS treatment (day 36), and 30 d after GOS feeding stopped and consumption of dairy products was encouraged (day 66)...
January 17, 2017: Proceedings of the National Academy of Sciences of the United States of America
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