keyword
https://read.qxmd.com/read/38648717/a-method-for-analyzing-afm-force-mapping-data-obtained-from-soft-tissue-cryosections
#1
JOURNAL ARTICLE
Cydney A Wong, Nina Sara Fraticelli Guzmán, A Thomas Read, Adam Hedberg-Buenz, Michael G Anderson, Andrew J Feola, Todd Sulchek, C Ross Ethier
Atomic force microscopy (AFM) is a valuable tool for assessing mechanical properties of biological samples, but interpretations of measurements on whole tissues can be difficult due to the tissue's highly heterogeneous nature. To overcome such difficulties and obtain more robust estimates of tissue mechanical properties, we describe an AFM force mapping and data analysis pipeline to characterize the mechanical properties of cryosectioned soft tissues. We assessed this approach on mouse optic nerve head and rat trabecular meshwork, cornea, and sclera...
April 19, 2024: Journal of Biomechanics
https://read.qxmd.com/read/38632550/statin-use-for-cardiovascular-disease-prevention-perceptions-among-people-living-with-hiv-in-the-united-states
#2
JOURNAL ARTICLE
Adedotun Ogunbajo, Ivy Todd, Deborah Zajdman, Abraelle Anderson, Soma Wali, Allison Diamant, Joseph A Ladapo, Allison J Ober
BACKGROUND: People living with HIV (PLWH) may be at heightened risk for cardiovascular disease (CVD). Statin use and lifestyle changes reduce the risk of CVD but remain under-prescribed among PLWH. The objective of this study was to characterize knowledge of CVD and statin use, current usage, barriers to taking statins, and information desired by PLWH to improve statin uptake among PLWH in Los Angeles, CA. METHODS: Between April 2019 and April 2020, we conducted four focus group discussions (n = 37) with patients across three public community health clinics that serve PLWH in Los Angeles County, California...
April 17, 2024: BMC Prim Care
https://read.qxmd.com/read/38629957/association-between-colonoscopy-sedation-type-and-polyp-detection-a-registry-based-cohort-study
#3
JOURNAL ARTICLE
Aurora N Quaye, William M Hisey, Todd A Mackenzie, Christina M Robinson, Janelle M Richard, Joseph C Anderson, Robert D Warters, Lynn F Butterly
BACKGROUND: Colorectal cancer is a leading cause of cancer-related death. Adenomas and serrated polyps are precursors of colorectal cancer, with serrated polyps being more difficult to detect during colonoscopy. The relationship between propofol use and polyp detection remains unclear. The authors investigated the association of propofol-based versus mild-moderate sedation on adenoma and serrated polyp detection during colonoscopy. METHODS: This retrospective cohort study used observational data from the New Hampshire Colonoscopy Registry...
April 17, 2024: Anesthesiology
https://read.qxmd.com/read/38614157/timing-of-intraoperative-neurophysiological-monitoring-ionm-recovery-and-clinical-recovery-after-termination-of-pediatric-spinal-deformity-surgery-due-to-loss-of-ionm-signals
#4
JOURNAL ARTICLE
Travis S CreveCoeur, Rajiv R Iyer, Hannah E Goldstein, Mychael W Delgardo, Todd C Hankinson, Mark A Erickson, Sumeet Garg, David L Skaggs, Lindsay Andras, Benjamin C Kennedy, Patrick J Cahill, Lawrence G Lenke, Peter D Angevine, Benjamin D Roye, Michael G Vitale, Anil Mendiratta, Richard C E Anderson
BACKGROUND CONTEXT: Intraoperative neurophysiological monitoring (IONM) is used to reduce the risk of spinal cord injury during pediatric spinal deformity surgery. Significant reduction and/or loss of IONM signals without immediate recovery may lead the surgeon to acutely abort the case. The timing of when monitorable signals return remains largely unknown. PURPOSE: The goal of this study was to investigate the correlation between IONM signal loss, clinical examination, and subsequent normalization of IONM signals after aborted pediatric spinal deformity surgery to help determine when it is safe to return to the operating room...
April 11, 2024: Spine Journal: Official Journal of the North American Spine Society
https://read.qxmd.com/read/38579359/the-role-of-occipital-condyle-and-atlas-anomalies-on-occipital-cervical-fusion-outcomes-in-chiari-malformation-type-i-with-syringomyelia-a-study-from-the-park-reeves-syringomyelia-research-consortium
#5
JOURNAL ARTICLE
Alexander T Yahanda, Joyce Koueik, Laurie L Ackerman, P David Adelson, Gregory W Albert, Philipp R Aldana, Tord D Alden, Richard C E Anderson, David F Bauer, Tammy Bethel-Anderson, Karin Bierbrauer, Douglas L Brockmeyer, Joshua J Chern, Daniel E Couture, David J Daniels, Brian J Dlouhy, Susan R Durham, Richard G Ellenbogen, Ramin Eskandari, Herbert E Fuchs, Gerald A Grant, Patrick C Graupman, Stephanie Greene, Jeffrey P Greenfield, Naina L Gross, Daniel J Guillaume, Todd C Hankinson, Gregory G Heuer, Mark Iantosca, Bermans J Iskandar, Eric M Jackson, George I Jallo, James M Johnston, Bruce A Kaufman, Robert F Keating, Nickalus R Khan, Mark D Krieger, Jeffrey R Leonard, Cormac O Maher, Francesco T Mangano, Jonathan Martin, J Gordon McComb, Sean D McEvoy, Thanda Meehan, Arnold H Menezes, Michael S Muhlbauer, Brent R O'Neill, Greg Olavarria, John Ragheb, Nathan R Selden, Manish N Shah, Chevis N Shannon, Joshua S Shimony, Matthew D Smyth, Scellig S D Stone, Jennifer M Strahle, Mandeep S Tamber, James C Torner, Gerald F Tuite, Elizabeth C Tyler-Kabara, Scott D Wait, John C Wellons, William E Whitehead, Tae Sung Park, David D Limbrick, Raheel Ahmed
OBJECTIVE: Congenital anomalies of the atlanto-occipital articulation may be present in patients with Chiari malformation type I (CM-I). However, it is unclear how these anomalies affect the biomechanical stability of the craniovertebral junction (CVJ) and whether they are associated with an increased incidence of occipitocervical fusion (OCF) following posterior fossa decompression (PFD). The objective of this study was to determine the prevalence of condylar hypoplasia and atlas anomalies in children with CM-I and syringomyelia...
April 5, 2024: Journal of Neurosurgery. Pediatrics
https://read.qxmd.com/read/38567668/evaluating-readability-understandability-and-actionability-of-online-printable-patient-education-materials-for-cholesterol-management-a-systematic-review
#6
JOURNAL ARTICLE
Chaitanya Bhatt, Ethan Lin, Laura E Ferreira-Legere, Cynthia A Jackevicius, Dennis T Ko, Douglas S Lee, Kathryn Schade, Sharon Johnston, Todd J Anderson, Jacob A Udell
BACKGROUND: Dyslipidemia management is a cornerstone in cardiovascular disease prevention and relies heavily on patient adherence to lifestyle modifications and medications. Numerous cholesterol patient education materials are available online, but it remains unclear whether these resources are suitable for the majority of North American adults given the prevalence of low health literacy. This review aimed to (1) identify printable cholesterol patient education materials through an online search, and (2) evaluate the readability, understandability, and actionability of each resource to determine its utility in practice...
April 3, 2024: Journal of the American Heart Association
https://read.qxmd.com/read/38546135/heterogeneity-of-coronary-vascular-function-and-myocardial-oxygenation-in-women-with-angina-and-non-obstructive-coronary-artery-disease
#7
JOURNAL ARTICLE
Elizabeth Hillier, Malik Elharram, James A White, Todd Anderson, Judy Luu, Dina Labib, Muhammad Alhussein, Matthias G Friedrich, Louise Pilote
AIMS: Women with angina and non-obstructive coronary artery disease (ANOCA) have a heightened risk for cardiovascular events, and the pathophysiology for ischemic symptoms may be related to alterations in microvascular structure and function. We examined the use of breathing-enhanced oxygenation-sensitive cardiac magnetic resonance imaging (OS-CMR) using vasoactive breathing maneuvers to assess myocardial oxygenation in women with ANOCA. METHODS AND RESULTS: We recruited women (aged 40-65 years) from two sites in Canada who presented to healthcare with persistent retrosternal chest pain and found to have ANOCA, or without a history of cardiovascular disease...
March 28, 2024: European Heart Journal Cardiovascular Imaging
https://read.qxmd.com/read/38400102/safety-and-immunogenicity-of-the-monovalent-omicron-xbb-1-5-adapted-bnt162b2-covid-19-vaccine-in-individuals-%C3%A2-12-years-old-a-phase-2-3-trial
#8
JOURNAL ARTICLE
Juleen Gayed, Oyeniyi Diya, Francine S Lowry, Xia Xu, Vishva Bangad, Federico Mensa, Jing Zou, Xuping Xie, Yanping Hu, Claire Lu, Mark Cutler, Todd Belanger, David Cooper, Kenneth Koury, Annaliesa S Anderson, Özlem Türeci, Uǧur Şahin, Kena A Swanson, Kayvon Modjarrad, Alejandra Gurtman, Nicholas Kitchin
Vaccination remains an important mitigation tool against COVID-19. We report 1-month safety and preliminary immunogenicity data from a substudy of an ongoing, open-label, phase 2/3 study of monovalent Omicron XBB.1.5-adapted BNT162b2 (single 30-μg dose). Healthy participants ≥12 years old ( N = 412 (12-17 years, N = 30; 18-55 years, N = 174; >55 years, N = 208)) who previously received ≥3 doses of a US-authorized mRNA vaccine, the most recent being an Omicron BA.4/BA.5-adapted bivalent vaccine ≥150 days before study vaccination, were vaccinated...
January 24, 2024: Vaccines
https://read.qxmd.com/read/38307660/status-migrainosus
#9
REVIEW
Salwa Kamourieh, Todd Rozen, Jane M Anderson
Status migrainosus is one of the recognized complications of migraine with or without aura, defined as a persistent debilitating migraine attack lasting for more than 72h with little reprieve, leading to functional disability. The individual impact of status migrainosus and the substantial healthcare burden are highlighted. Current case series which inform our understanding of this condition are examined with two groups emergent, those with classic status migrainosus and those with episodic status migrainosus...
2024: Handbook of Clinical Neurology
https://read.qxmd.com/read/38257860/assessment-of-potential-anti-methanogenic-and-antimicrobial-activity-of-ethyl-nitroacetate-%C3%AE-lipoic-acid-taurine-and-l-cysteinesulfinic-acid-in-vitro
#10
JOURNAL ARTICLE
Gizem Levent, Aleksandar Božić, Branko T Petrujkić, Todd R Callaway, Toni L Poole, Tawni L Crippen, Roger B Harvey, Pedro Ochoa-García, Agustin Corral-Luna, Kathleen M Yeater, Robin C Anderson
Livestock producers need new technologies to maintain the optimal health and well-being of their animals while minimizing the risks of propagating and disseminating pathogenic and antimicrobial-resistant bacteria to humans or other animals. Where possible, these interventions should contribute to the efficiency and profitability of animal production to avoid passing costs on to consumers. In this study, we examined the potential of nitroethane, 3-nitro-1-propionate, ethyl nitroacetate, taurine and L-cysteinesulfinic acid to modulate rumen methane production, a digestive inefficiency that results in the loss of up to 12% of the host's dietary energy intake and a major contributor of methane as a greenhouse gas to the atmosphere...
December 23, 2023: Microorganisms
https://read.qxmd.com/read/38222805/paraspinal-muscles-in-individuals-undergoing-surgery-for-lumbar-spine-pathology-lack-a-myogenic-response-to-an-acute-bout-of-resistance-exercise
#11
JOURNAL ARTICLE
Bahar Shahidi, Bradley Anderson, Angel Ordaz, David B Berry, Severin Ruoss, Vinko Zlomislic, R Todd Allen, Steven R Garfin, Mazda Farshad, Simon Schenk, Samuel R Ward
BACKGROUND: Lumbar spine pathology (LSP) is a common source of low back or leg pain, and paraspinal muscle in these patients demonstrates fatty and fibrotic infiltration, and cellular degeneration that do not reverse with exercise-based rehabilitation. However, it is unclear of this lack of response is due to insufficient exercise stimulus, or an inability to mount a growth response. The purpose of this study was to compare paraspinal muscle gene expression between individuals with LSP who do and do not undergo an acute bout of resistance exercise...
March 2024: JOR Spine
https://read.qxmd.com/read/38204849/chest-pain-evaluation-diagnostic-testing
#12
REVIEW
Benjamin J W Chow, Paul Galiwango, Anthony Poulin, Paolo Raggi, Gary Small, Daniel Juneau, Mustapha Kazmi, Bilal Ayach, Rob S Beanlands, Anthony J Sanfilippo, Chi-Ming Chow, D Ian Paterson, Michael Chetrit, Davinder S Jassal, Kim Connelly, Eric Larose, Helen Bishop, Malek Kass, Todd J Anderson, Haissam Haddad, John Mancini, Katie Doucet, Jean-Sebastien Daigle, Amir Ahmadi, Jonathan Leipsic, Siok Ping Lim, Andrew McRae, Annie Y Chou
Chest pain/discomfort (CP) is a common symptom and can be a diagnostic dilemma for many clinicians. The misdiagnosis of an acute or progressive chronic cardiac etiology may carry a significant risk of morbidity and mortality. This review summarizes the different options and modalities for establishing the diagnosis and severity of coronary artery disease. An effective test selection algorithm should be individually tailored to each patient to maximize diagnostic accuracy in a timely fashion, determine short- and long-term prognosis, and permit implementation of evidence-based treatments in a cost-effective manner...
December 2023: CJC open
https://read.qxmd.com/read/38150869/development-of-an-international-virtual-multidisciplinary-tumor-board-for-breast-cancer-in-mongolia
#13
JOURNAL ARTICLE
Kirstyn E Brownson, Angel Flores-Huidobro Martinez, Javkhlan Ganbayar, Leif M Sorensen, Anna M Darelli-Anderson, Saranya Prathibha, Noelle Hoven, Erdenekhuu Nansalmaa, Jonathon Mahlow, Batsukh Pushkin, David Potter, Todd Tuttle, Raymond R Price
INTRODUCTION: Breast cancer is the most diagnosed cancer among Mongolian women and mortality rates are high. We describe a virtual multi-institutional and multidisciplinary tumor board (MTB) for breast cancer created to assist the National Cancer Center of Mongolia. MATERIALS AND METHODS: A virtual MTB for breast cancer was conducted with participation of two United States and 1 Mongolian cancer centers. A standardized template for presentations was developed. Recommendations were summarized and shared with participants...
December 26, 2023: Journal of Surgical Research
https://read.qxmd.com/read/38149373/prevalence-and-spectrum-of-infectious-and-inflammatory-dermatologic-conditions-occurring-in-pediatric-heart-transplant-patients-on-a-predominantly-mtor-based-immune-suppressive-regimen-a-retrospective-chart-review
#14
JOURNAL ARTICLE
Ann Rydberg, Rebecca Ameduri, Trista Brown, Jonathan N Johnson, Austin Todd, Megha M Tollefson, Katelyn Anderson
INTRODUCTION: Pediatric heart transplant patients are routinely followed in dermatology clinics due to elevated risk of cutaneous malignancy. However, transplant patients may experience other, non-cancer-related dermatologic conditions including skin infections, inflammatory diseases, and drug eruptions that can cause significant medical and psychosocial comorbidity. METHODS: A retrospective chart review of all pediatric heart transplant patients at Mayo Clinic Children's Center in Rochester, MN, was performed to determine the prevalence and spectrum of non-cancer dermatologic conditions...
February 2024: Pediatric Transplantation
https://read.qxmd.com/read/38137076/a-comparison-of-neuropsychological-outcomes-following-responsive-neurostimulation-and-anterior-temporal-lobectomy-in-drug-resistant-epilepsy
#15
JOURNAL ARTICLE
Carly M O'Donnell, Christopher Todd Anderson, Anthony J Oleksy, Sara J Swanson
Neuropsychological outcomes following temporal lobe resection for drug-resistant epilepsy (DRE) are well established. For instance, left anterior temporal lobectomy (LATL) is associated with a greater risk for cognitive morbidity compared to right (RATL). However, the impact of neuromodulatory devices, specifically responsive neurostimulation (RNS), remains an area of active interest. There are currently no head-to-head comparisons of neuropsychological outcomes after surgical resection and neuromodulation...
November 24, 2023: Brain Sciences
https://read.qxmd.com/read/38133276/-campylobacter-jejuni-response-when-inoculated-in-bovine-in-vitro-fecal-microbial-consortia-incubations-in-the-presence-of-metabolic-inhibitors
#16
JOURNAL ARTICLE
Dana K Dittoe, Robin C Anderson, Nathan A Krueger, Roger B Harvey, Toni L Poole, Tawni L Crippen, Todd R Callaway, Steven C Ricke
Infection with the foodborne pathogen Campylobacter is the leading bacterial cause of human foodborne illness in the United States. The objectives of this experiment were to test the hypothesis that mixed microbial populations from the bovine rumen may be better at excluding Campylobacter than populations from freshly voided feces and to explore potential reasons as to why the rumen may be a less favorable environment for Campylobacter than feces. In an initial experiment, C. jejuni cultures inoculated without or with freshly collected bovine rumen fluid, bovine feces or their combination were cultured micro-aerobically for 48 h...
November 26, 2023: Pathogens
https://read.qxmd.com/read/38079638/development-and-validation-of-the-canheart-population-based-laboratory-prediction-models-for-atherosclerotic-cardiovascular-disease
#17
JOURNAL ARTICLE
Maneesh Sud, Atul Sivaswamy, Peter C Austin, Todd J Anderson, David M J Naimark, Michael E Farkouh, Douglas S Lee, Idan Roifman, George Thanassoulis, Karen Tu, Jacob A Udell, Harindra C Wijeysundera, Dennis T Ko
BACKGROUND: Prediction of atherosclerotic cardiovascular disease (ASCVD) in primary prevention assessments exclusively with laboratory results may facilitate automated risk reporting and improve uptake of preventive therapies. OBJECTIVE: To develop and validate sex-specific prediction models for ASCVD using age and routine laboratory tests and compare their performance with that of the pooled cohort equations (PCEs). DESIGN: Derivation and validation of the CANHEART (Cardiovascular Health in Ambulatory Care Research Team) Lab Models...
December 2023: Annals of Internal Medicine
https://read.qxmd.com/read/38040869/author-correction-ongoing-declines-for-the-world-s-amphibians-in-the-face-of-emerging-threats
#18
Jennifer A Luedtke, Janice Chanson, Kelsey Neam, Louise Hobin, Adriano O Maciel, Alessandro Catenazzi, Amaël Borzée, Amir Hamidy, Anchalee Aowphol, Anderson Jean, Ángel Sosa-Bartuano, Ansel Fong G, Anslem de Silva, Antoine Fouquet, Ariadne Angulo, Artem A Kidov, Arturo Muñoz Saravia, Arvin C Diesmos, Atsushi Tominaga, Biraj Shrestha, Brian Gratwicke, Burhan Tjaturadi, Carlos C Martínez Rivera, Carlos R Vásquez Almazán, Celsa Señaris, S R Chandramouli, Christine Strüssmann, Claudia Fabiola Cortez Fernández, Claudio Azat, Conrad J Hoskin, Craig Hilton-Taylor, Damion L Whyte, David J Gower, Deanna H Olson, Diego F Cisneros-Heredia, Diego José Santana, Elizah Nagombi, Elnaz Najafi-Majd, Evan S H Quah, Federico Bolaños, Feng Xie, Francisco Brusquetti, Francisco S Álvarez, Franco Andreone, Frank Glaw, Franklin Enrique Castañeda, Fred Kraus, Gabriela Parra-Olea, Gerardo Chaves, Guido F Medina-Rangel, Gustavo González-Durán, H Mauricio Ortega-Andrade, Iberê F Machado, Indraneil Das, Iuri Ribeiro Dias, J Nicolas Urbina-Cardona, Jelka Crnobrnja-Isailović, Jian-Huan Yang, Jiang Jianping, Jigme Tshelthrim Wangyal, Jodi J L Rowley, John Measey, Karthikeyan Vasudevan, Kin Onn Chan, Kotambylu Vasudeva Gururaja, Kristiina Ovaska, Lauren C Warr, Luis Canseco-Márquez, Luís Felipe Toledo, Luis M Díaz, M Monirul H Khan, Madhava Meegaskumbura, Manuel E Acevedo, Marcelo Felgueiras Napoli, Marcos A Ponce, Marcos Vaira, Margarita Lampo, Mario H Yánez-Muñoz, Mark D Scherz, Mark-Oliver Rödel, Masafumi Matsui, Maxon Fildor, Mirza D Kusrini, Mohammad Firoz Ahmed, Muhammad Rais, N'Goran G Kouamé, Nieves García, Nono Legrand Gonwouo, Patricia A Burrowes, Paul Y Imbun, Philipp Wagner, Philippe J R Kok, Rafael L Joglar, Renoir J Auguste, Reuber Albuquerque Brandão, Roberto Ibáñez, Rudolf von May, S Blair Hedges, S D Biju, S R Ganesh, Sally Wren, Sandeep Das, Sandra V Flechas, Sara L Ashpole, Silvia J Robleto-Hernández, Simon P Loader, Sixto J Incháustegui, Sonali Garg, Somphouthone Phimmachak, Stephen J Richards, Tahar Slimani, Tamara Osborne-Naikatini, Tatianne P F Abreu-Jardim, Thais H Condez, Thiago R De Carvalho, Timothy P Cutajar, Todd W Pierson, Truong Q Nguyen, Uğur Kaya, Zhiyong Yuan, Barney Long, Penny Langhammer, Simon N Stuart
No abstract text is available yet for this article.
December 1, 2023: Nature
https://read.qxmd.com/read/38026485/feasibility-and-safety-of-planned-early-discharge-following-laparotomy-in-gynecologic-oncology-with-enhanced-recovery-protocol-including-opioid-sparing-anesthesia
#19
JOURNAL ARTICLE
Michelle L Kuznicki, Maya Yasukawa, Adrianne R Mallen, Clarissa Lam, Erica Eggers, Jefferson Regis, Ali Wells, Sarah L Todd, Sharon E Robertson, Jean-Paul Tanner, Matthew L Anderson, Thomas J Rutherford
OBJECTIVE: This study aims to evaluate the feasibility and safety of planned postoperative day 1 discharge (PPOD1) among patients who undergo laparotomy (XL) in the department of gynecology oncology utilizing a modified enhanced recovery after surgery (ERAS) protocol including opioid-sparing anesthesia (OSA) and defined discharge criteria. METHODS: Patients undergoing XL and minimally invasive surgery (MIS) were enrolled in this prospective, observational cohort study after the departmental implementation of a modified ERAS protocol...
2023: Frontiers in Surgery
https://read.qxmd.com/read/38016977/identification-of-brain-areas-in-mice-with-peak-neural-activity-across-the-acute-and-persistent-phases-of-post-traumatic-headache
#20
JOURNAL ARTICLE
Megan Rudolph, Caroline Kopruszinski, Chen Wu, Edita Navratilova, Todd J Schwedt, David W Dodick, Frank Porreca, Trent Anderson
BACKGROUND: Post-traumatic headache is very common after a mild traumatic brain injury. Post-traumatic headache may persist for months to years after an injury in a substantial proportion of people. The pathophysiology underlying post-traumatic headache remains unknown but is likely distinct from other headache disorders. Identification of brain areas activated in acute and persistent phases of post-traumatic headache can provide insights into the underlying circuits mediating headache pain...
November 2023: Cephalalgia: An International Journal of Headache
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