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Todd Anderson

Kasra Zarei, Todd E Scheetz, Mark Christopher, Kathy Miller, Adam Hedberg-Buenz, Anamika Tandon, Michael G Anderson, John H Fingert, Michael David Abràmoff
No abstract text is available yet for this article.
October 19, 2016: Scientific Reports
Todd J Anderson, Bo Zhang
Metal nanoparticles are key electrode materials in a variety of electrochemical applications including basic electron-transfer study, electrochemical sensing, and electrochemical surface enhanced Raman spectroscopy (SERS). Metal nanoparticles have also been extensively applied to electrocatalytic processes in recent years due to their high catalytic activity and large surface areas. Because the catalytic activity of metal nanoparticle is often highly dependent on their size, shape, surface ligands, and so forth, methods for examining and better understanding the correlation between particle structure and function are of great utility in the development of more efficient catalytic systems...
October 12, 2016: Accounts of Chemical Research
Todd J Anderson, Jean Grégoire, Glen J Pearson, Arden R Barry, Patrick Couture, Martin Dawes, Gordon A Francis, Jacques Genest, Steven Grover, Milan Gupta, Robert A Hegele, David C Lau, Lawrence A Leiter, Eva Lonn, G B John Mancini, Ruth McPherson, Daniel Ngui, Paul Poirier, John L Sievenpiper, James A Stone, George Thanassoulis, Richard Ward
Since the publication of the 2012 guidelines new literature has emerged to inform decision-making. The 2016 guidelines primary panel selected a number of clinically relevant questions and has produced updated recommendations, on the basis of important new findings. In subjects with clinical atherosclerosis, abdominal aortic aneurysm, most subjects with diabetes or chronic kidney disease, and those with low-density lipoprotein cholesterol ≥ 5 mmol/L, statin therapy is recommended. For all others, there is an emphasis on risk assessment linked to lipid determination to optimize decision-making...
July 25, 2016: Canadian Journal of Cardiology
Jose R Castillo-Mancilla, Todd T Brown, Kristine M Erlandson, Frank J Palella, Edward M Gardner, Bernard J C Macatangay, Elizabeth C Breen, Lisa P Jacobson, Peter L Anderson, Nikolas I Wada
BACKGROUND:  HIV-infected individuals exhibit residual inflammation regardless of virologic suppression. We evaluated whether suboptimal adherence to combination antiretroviral therapy (cART) is associated with greater residual inflammation compared to optimal adherence despite virologic suppression. METHODS:  Longitudinal self-reported cART adherence data and serum concentrations of 24 biomarkers of inflammation and immune activation were measured at the same study visit in HIV RNA-suppressed (<50 copies/mL) HIV-infected men in the Multicenter AIDS Cohort Study from 1998 to 2009...
September 22, 2016: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
Kristian M Koller, Wenge Wang, Todd D Schell, Eugene M Cozza, Kathleen M Kokolus, Rogerio I Neves, Heath B Mackley, Colette Pameijer, Anna Leung, Bryan Anderson, Carol A Mallon, Gavin Robertson, Joseph J Drabick
One of the defining characteristics of the malignant phenotype is the ability to evade the host immune system. Immunotherapy as a treatment modality represents a new dawn in the way we think about the treatment of a variety of malignancies. The story of immunotherapy traces its roots to its relationship with malignant melanoma. In this article, we review the intertwined history of immunotherapy and melanoma, including the early significant history, a discussion on immune mechanisms, resistance, local and systemic immunotherapeutic modalities, and speculate on possible novel future treatment options...
October 2016: Critical Reviews in Oncology/hematology
Kristin A Rand, Chi Song, Eric Dean, Daniel J Serie, Karen Curtin, Xin Sheng, Donglei Hu, Carol Ann Huff, Leon Bernal-Mizrachi, Michael H Tomasson, Sikander Ailwadhi, Seema Singhal, Karen S Pawlish, Edward S Peters, Cathryn H BLock, Alexander Stram, David J Van Den Berg, Christopher K Edlund, David V Conti, Todd M Zimmerman, Amie E Hwang, Scott Huntsman, John J Graff, Ajay Nooka, Yinfei Kong, Silvana L Pregja, Sonja I Berndt, William J Blot, John D Carpten, Graham Casey, Lisa W Chu, W Ryan Diver, Victoria L Stevens, MIchael R Lieber, Phyllis J Goodman, Anselm J M Hennis, Ann W Hsing, Jayesh Mehta, Rick A Kittles, Suzanne Kolb, Eric A Klein, Cristina M Leske, Adam B Murphy, Barbara Nemesure, Christine Neslund-Dudas, Sara S Strom, Ravi Vij, Benjamin A Rybicki, Janet L Stanford, Lisa Signorello, John S Witte, Christine B Ambrosone, Parveen Bhatti, Esther M John, Leslie Bernstein, Wei Zheng, Andrew F Olshan, Jennifer J Hu, Regina G Ziegler, Sarah J Nyante, Elisa V Bandera, Brenda M Birmann, Sue Ann Ingles, Michael F Press, Djordje Atanackovic, Martha Glenn, Lisa Cannon-Albright, Brandt Jones, Guido Tricot, Thomas G Martin, Shaji K Kumar, Jeffrey L Wolf, Sandra L Deming, Nathaniel Rothman, Angela Brooks-Wilson, S Vincent Rajkumar, Laurence N Kolonel, Stephen J Chanock, Susan L Slager, Richard K Severson, Nalini Janakirman, Howard J Terebelo, Elizabeth E Brown, Anneclaire J De Roos, Ann Mohrbacher, Graham A Colditz, Graham G Giles, John J Spinelli, Brian C Chiu, Nikhil C Munshi, Kenneth C Anderson, Joan Levy, Jeffrey A Zonder, Robert Z Orlowski, Sagar Lonial, Nicola J Camp, Celine M Vachon, Elad Ziv, Daniel O Stram, Dennis J Hazelett, Wendy Cozen
BACKGROUND: Genome-wide association studies (GWAS) in European populations have identified genetic risk variants associated with multiple myeloma (MM). METHODS: We performed association testing of common variation in eight regions in 1,264 MM patients and 1,479 controls of European ancestry (EA) and 1,305 MM patients and 7,078 controls of African ancestry (AA) and conducted a meta-analysis to localize the signals, with epigenetic annotation used to predict functionality...
September 1, 2016: Cancer Epidemiology, Biomarkers & Prevention
Robin C Anderson, Laura H Ripley, Jan G P Bowman, Todd R Callaway, Kenneth J Genovese, Ross C Beier, Roger B Harvey, David J Nisbet
Nitrate, 3-nitro-1-propionic acid (NPA) and 3-nitro-1-propanol (NPOH) can accumulate in forages and be poisonous to animals if consumed in high enough amounts. These chemicals are also recognized as potent anti-methanogenic compounds, but plants naturally containing these chemicals have been studied little in this regard. Presently, we found that nitrate-, NPA-, or NPOH-containing forages effectively decreased methane production, by 35-87%, during in vitro fermentation by mixed cultures of ruminal microbes compared to fermentation by cultures incubated similarly with alfalfa...
2016: Frontiers in Veterinary Science
Jamil M Beg, Thomas D Anderson, Kevin Francis, Lisa M Meckley, David Fitzhenry, Todd Foster, Susheel Sukhtankar, Stephen J Kanes, Lidia M V R Moura
OBJECTIVE: To provide an estimate of the annual number of super-refractory status epilepticus (SRSE) cases in the US and to evaluate utilization of hospital resources by these patients. METHODS: The Premier Hospital Database was utilized to estimate the number of SRSE cases based on hospital discharges during 2012. Discharges were classified as SRSE cases based on an algorithm using seizure-related International Classification of Diseases-9 (ICD-9) codes, Intensive Care Unit (ICU) length of stay (LOS), and treatment protocols (e...
August 11, 2016: Journal of Medical Economics
Amirali Sayadipour, Chrisopher K Kepler, Rajnish Mago, Kenneth M Certa, Mohammad R Rasouli, Alexander R Vaccaro, Todd J Albert, David G Anderson
BACKGROUND: It has been suggested, although not proven, that presence of concomitant psychiatric disorders may increase the inpatient costs for patients undergoing elective surgery. This study was designed to test the hypothesis that elective lumbar fusion surgery is more costly in patients with under treatment for depression. METHODS: This is a retrospective case-control study of 142 patients who underwent elective lumbar fusion. Of those 142 patients, 41 patients were chronically using an antidepressant medication that considered as a "study group", and 101 patients were not taking an antidepressant medication that considered as a "control group"...
June 2016: Archives of Bone and Joint Surgery
Lipsa Das, Todd A Anderson, Jaime M C Gard, Isis C Sroka, Stephanie R Strautman, Raymond B Nagle, Colm Morrissey, Beatrice S Knudsen, Anne E Cress
Laminin binding integrins α6 (CD49f) and α3 (CD49c) are persistently but differentially expressed in prostate cancer (PCa). Integrin internalization is an important determinant of their cell surface expression and function. Using flow cytometry, and first order kinetic modelling, we quantitated the intrinsic internalization rates of integrin subunits in a single cycle of internalization. In PCa cell line DU145, α6 integrin internalized with a rate constant (kactual ) of 3.25min(-1) , 3-fold faster than α3 integrin (1...
August 10, 2016: Journal of Cellular Biochemistry
Jacquelyn Freund, Rebecca M May, Enjun Yang, Hongchuan Li, Matthew McCullen, Bin Zhang, Todd Lenvik, Frank Cichocki, Stephen K Anderson, Taku Kambayashi
It has recently been appreciated that NK cells exhibit many features reminiscent of adaptive immune cells. Considerable heterogeneity exists with respect to the ligand specificity of individual NK cells and as such, a subset of NK cells can respond, expand, and differentiate into memory-like cells in a ligand-specific manner. MHC I-binding inhibitory receptors, including those belonging to the Ly49 and KIR families, are expressed in a variegated manner, which creates ligand-specific diversity within the NK cell pool...
August 2016: PLoS Biology
Ross C Beier, Eelco Franz, James L Bono, Robert E Mandrell, Pina M Fratamico, Todd R Callaway, Kathleen Andrews, Toni L Poole, Tawni L Crippen, Cynthia L Sheffield, Robin C Anderson, David J Nisbet
The disinfectant and antimicrobial susceptibility profiles of 138 non-O157 Shiga toxin-producing Escherichia coli strains (STECs) from food animals and humans were determined. Antimicrobial resistance (AMR) was moderate (39.1% of strains) in response to 15 antimicrobial agents. Animal strains had a lower AMR prevalence (35.6%) than did human strains (43.9%) but a higher prevalence of the resistance profile GEN-KAN-TET. A decreasing prevalence of AMR was found among animal strains from serogroups O45 > O145 > O121 > O111 > O26 > O103 and among human strains from serogroups O145 > O103 > O26 > O111 > O121 > O45...
August 2016: Journal of Food Protection
M Elizabeth Wilcox, Elizabeth A Freiheit, Peter Faris, David B Hogan, Scott B Patten, Todd Anderson, William A Ghali, Merril Knudtson, Andrew Demchuk, Colleen J Maxwell
BACKGROUND: Depressive symptoms are prevalent in patients with coronary artery disease (CAD). It is unclear, however, how depressive symptoms change over time and the impact of these changes on long-term functional outcomes. We examined the association between different trajectories of depressive symptoms over 1 year and change in functional status over 30 months among patients undergoing coronary angiography. METHODS: This was a prospective cohort study of 350 patients aged 60 and older undergoing non-emergent cardiac catheterization (October 2003-February 2007)...
2016: BMC Psychiatry
Ahmed F Elsayem, Eduardo Bruera, Alan D Valentine, Carla L Warneke, Sai-Ching J Yeung, Valda D Page, Geri L Wood, Julio Silvestre, Holly M Holmes, Patricia A Brock, Knox H Todd
BACKGROUND: The frequency of delirium among patients with cancer presenting to the emergency department (ED) is unknown. The purpose of this study was to determine delirium frequency and recognition by ED physicians among patients with advanced cancer presenting to the ED of The University of Texas MD Anderson Cancer Center. METHODS: The study population was a random sample of English-speaking patients with advanced cancer who presented to the ED and met the study criteria...
September 15, 2016: Cancer
David A Kalmbach, Vivek Pillai, J Todd Arnedt, Jason R Anderson, Christopher L Drake
OBJECTIVES: To test for sensitization of the sleep system in response to insomnia development and major life stress. In addition, to evaluate the impact on depression and anxiety associated with sleep system sensitization. METHODS: A longitudinal study with three annual assessments. The community-based sample included 262 adults with no history of insomnia or depression who developed insomnia one year after baseline (67.6% female; 44.0 ± 13.4 yr). Measures included the Ford Insomnia Response to Stress Test to assess sleep reactivity, Quick Inventory of Depressive Symptomatology, and Beck Anxiety Inventory...
May 2016: Sleep Medicine
Kevin Dibbern, Laurence B Kempton, Thomas F Higgins, Saam Morshed, Todd O McKinley, J Lawrence Marsh, Donald D Anderson
Patients with tibial pilon fractures have a higher incidence of post-traumatic osteoarthritis than those with fractures of the tibial plateau. This may indicate that pilon fractures present a greater mechanical insult to the joint than do plateau fractures. We tested the hypothesis that fracture energy and articular fracture edge length, two independent indicators of severity, are higher in pilon than plateau fractures. We also evaluated if clinical fracture classification systems accurately reflect severity...
July 6, 2016: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
Bertram L Kasiske, Rajiv Kumar, Paul L Kimmel, Todd E Pesavento, Roberto S Kalil, Edward S Kraus, Hamid Rabb, Andrew M Posselt, Teresa L Anderson-Haag, Michael W Steffes, Ajay K Israni, Jon J Snyder, Ravinder J Singh, Matthew R Weir
Previous studies have suggested that kidney donors may have abnormalities of mineral and bone metabolism typically seen in chronic kidney disease. This may have important implications for the skeletal health of living kidney donors and for our understanding of the pathogenesis of long-term mineral and bone disorders in chronic kidney disease. In this prospective study, 182 of 203 kidney donors and 173 of 201 paired normal controls had markers of mineral and bone metabolism measured before and at 6 and 36 months after donation (ALTOLD Study)...
October 2016: Kidney International
Petr Neuzil, John Ormiston, Todd J Brinton, Zdenek Starek, Murray Esler, Omar Dawood, Thomas L Anderson, Michael Gertner, Rob Whitbourne, Roland E Schmieder
OBJECTIVES: The aim of this study was to assess clinical safety and efficacy outcomes of renal denervation executed by an externally delivered, completely noninvasive focused therapeutic ultrasound device. BACKGROUND: Renal denervation has emerged as a potential treatment approach for resistant hypertension. METHODS: Sixty-nine subjects received renal denervation with externally delivered focused ultrasound via the Kona Medical Surround Sound System...
June 27, 2016: JACC. Cardiovascular Interventions
Subbiah Seenivasan, Todd Alan Anderson, Narayanannair Muraleedharan
Soils contaminated with heavy metals may pose a threat to environment and human health if metals enter the food chain over and above threshold levels. In general, there is a lack of information on the presence of heavy metals in tea [Camellia sinensis (L). O. Kuntze] plants and the soils in which they are grown. Therefore, an attempt was made to establish a database on the important heavy metals: cadmium (Cd), chromium (Cr), nickel (Ni), and lead (Pb). For an initial survey on heavy metals, soil samples were collected randomly from tea-growing areas of Tamil Nadu, Kerala, and Karnataka, India...
July 2016: Environmental Monitoring and Assessment
Rishi Puri, Steven E Nissen, Ransi Somaratne, Leslie Cho, John J P Kastelein, Christie M Ballantyne, Wolfgang Koenig, Todd J Anderson, Jingyuan Yang, Helina Kassahun, Scott M Wasserman, Robert Scott, Marilyn Borgman, Stephen J Nicholls
BACKGROUND: Statin-mediated low-density lipoprotein cholesterol (LDL-C) lowering fails to prevent more than half of cardiovascular events in clinical trials. Serial plaque imaging studies have highlighted the benefits of aggressive LDL-C lowering, with plaque regression evident in up to two-thirds of patients with achieved LDL-C levels <70 mg/dL. Proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors permit LDL-C-lowering by a further 54% to 75% in statin-treated patients...
June 2016: American Heart Journal
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