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Todd Anderson

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https://www.readbyqxmd.com/read/29016858/maternal-bmi-at-the-start-of-pregnancy-and-offspring-epigenome-wide-dna-methylation-findings-from-the-pregnancy-and-childhood-epigenetics-pace-consortium
#1
Gemma C Sharp, Lucas A Salas, Claire Monnereau, Catherine Allard, Paul Yousefi, Todd M Everson, Jon Bohlin, Zongli Xu, Rae-Chi Huang, Sarah E Reese, Cheng-Jian Xu, Nour Baïz, Cathrine Hoyo, Golareh Agha, Ritu Roy, John W Holloway, Akram Ghantous, Simon K Merid, Kelly M Bakulski, Leanne K Küpers, Hongmei Zhang, Rebecca C Richmond, Christian M Page, Liesbeth Duijts, Rolv T Lie, Phillip E Melton, Judith M Vonk, Ellen A Nohr, ClarLynda Williams-DeVane, Karen Huen, Sheryl L Rifas-Shiman, Carlos Ruiz-Arenas, Semira Gonseth, Faisal I Rezwan, Zdenko Herceg, Sandra Ekström, Lisa Croen, Fahimeh Falahi, Patrice Perron, Margaret R Karagas, Bilal M Quraishi, Matthew Suderman, Maria C Magnus, Vincent W V Jaddoe, Jack A Taylor, Denise Anderson, Shanshan Zhao, Henriette A Smit, Michele J Josey, Asa Bradman, Andrea A Baccarelli, Mariona Bustamante, Siri E Håberg, Göran Pershagen, Irva Hertz-Picciotto, Craig Newschaffer, Eva Corpeleijn, Luigi Bouchard, Debbie A Lawlor, Rachel L Maguire, Lisa F Barcellos, George Davey Smith, Brenda Eskenazi, Wilfried Karmaus, Carmen J Marsit, Marie-France Hivert, Harold Snieder, M Daniele Fallin, Erik Melén, Monica C Munthe-Kaas, Hasan Arshad, Joseph L Wiemels, Isabella Annesi-Maesano, Martine Vrijheid, Emily Oken, Nina Holland, Susan K Murphy, Thorkild I A Sørensen, Gerard H Koppelman, John P Newnham, Allen J Wilcox, Wenche Nystad, Stephanie J London, Janine F Felix, Caroline L Relton
Pre-pregnancy maternal obesity is associated with adverse offspring outcomes at birth and later in life. Individual studies have shown that epigenetic modifications such as DNA methylation could contribute. Within the Pregnancy and Childhood Epigenetics (PACE) Consortium, we meta-analysed the association between pre-pregnancy maternal BMI and methylation at over 450,000 sites in newborn blood DNA, across 19 cohorts (9,340 mother-newborn pairs). We attempted to infer causality by comparing the effects of maternal versus paternal BMI and incorporating genetic variation...
October 15, 2017: Human Molecular Genetics
https://www.readbyqxmd.com/read/28963880/protective-role-of-indoleamine-2-3-dioxygenase-in-respiratory-syncytial-virus-associated-immune-response-in-airway-epithelial-cells
#2
Devi Rajan, Raghavan Chinnadurai, Evan O Keefe, Seyhan Boyoglu-Barnum, Sean O Todd, Tina V Hartert, Jacques Galipeau, Larry J Anderson
RSV is a major cause of severe lower respiratory infection in infants and young children. With no vaccine yet available, it is important to clarify mechanisms of disease pathogenesis. Since indoleamine-2,3-dioxygenase (IDO) is an immunomodulatory enzyme and is upregulated with RSV infection, we studied it in vivo during infection of BALB/c mice and in vitro in A549 cells. RSV infection upregulated IDO transcripts in vivo and in vitro. IDO siRNA decreased IDO transcripts ~2 fold compared to control siRNA after RSV infection but this decrease did not affect RSV replication...
September 27, 2017: Virology
https://www.readbyqxmd.com/read/28959509/management-of-tiny-meningiomas-to-resect-or-not-resect
#3
Julia R Schneider, Kay O Kulason, Tim White, Bidyut Pramanik, Shamik Chakraborty, Linda Heier, Ashley E Ray, Todd A Anderson, Derek J Chong, John Boockvar
Meningiomas are most often benign primary intracranial tumors that are frequently found incidentally on imaging. Larger sized meningiomas may present with symptoms such as seizures and headaches. Smaller meningiomas are commonly asymptomatic and usually observed with serial imaging. We present two female patients, both of whom were found to have very small left frontal meningiomas that marginated Broca's area. The first patient in this case series experienced episodes resembling seizures which consisted of weakness, vision loss, and slurred speech, as well as subtle language dysfunction in her day-to-day conversations...
July 25, 2017: Curēus
https://www.readbyqxmd.com/read/28941609/association-of-apolipoproteins-b-and-a-1-with-markers-of-vascular-health-or-cardiovascular-events
#4
MULTICENTER STUDY
Yiming M Zhu, Subodh Verma, Marinda Fung, Matthew J McQueen, Todd J Anderson, Eva M Lonn
BACKGROUND: Apolipoprotein B (apoB) and apolipoprotein A-1 (apoA-1) are markers of lipoprotein metabolism. Although their relationship to cardiovascular disease has been well documented, little is known regarding their correlation to measures of vascular structure and function. This study was conducted to investigate the relationship between apoA-1, apoB, and measures of vascular function, as well their relationship to adverse cardiovascular events. Moreover, we evaluated whether apoB or the apoB/apoA-1 ratio was more closely related to vascular markers than was low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (non-HDL-C)...
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28881320/frequency-and-predictors-of-psychological-distress-after-a-diagnosis-of-epilepsy-a-community-based-study
#5
Ying Xu, Maree L Hackett, Nick Glozier, Armin Nikpour, Andrew Bleasel, Ernest Somerville, John Lawson, Stephen Jan, Lorne Hyde, Lisa Todd, Alexandra Martiniuk, Carol Ireland, Craig S Anderson
OBJECTIVE: The objective of the study was to determine the frequency and predictors of psychological distress after a diagnosis of epilepsy. METHODS: The Sydney Epilepsy Incidence Study to Measure Illness Consequences (SEISMIC) was a prospective, multicenter, community-based study of people of all ages with newly diagnosed epilepsy in Sydney, Australia. Analyses involved multivariate logistic regression and multinomial logit regression to identify predictors of psychological distress, assessed using the Hospital Anxiety and Depression Scale (HADS) and the Strengths and Difficulties Questionnaire (SDQ), as part of structured interviews...
September 4, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28866077/importance-of-optimization-of-cardiovascular-risk-factors-and-lifestyle-behaviours
#6
EDITORIAL
Todd J Anderson
No abstract text is available yet for this article.
October 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28859336/molecular-analyses-reveal-inflammatory-mediators-in-the-solid-component-and-cyst-fluid-of-human-adamantinomatous-craniopharyngioma
#7
MULTICENTER STUDY
Andrew M Donson, John Apps, Andrea M Griesinger, Vladimir Amani, Davis A Witt, Richard C E Anderson, Toba N Niazi, Gerald Grant, Mark Souweidane, James M Johnston, Eric M Jackson, Bette K Kleinschmidt-DeMasters, Michael H Handler, Aik-Choon Tan, Lia Gore, Alex Virasami, Jose Mario Gonzalez-Meljem, Thomas S Jacques, Juan Pedro Martinez-Barbera, Nicholas K Foreman, Todd C Hankinson
Pediatric adamantinomatous craniopharyngioma (ACP) is a highly solid and cystic tumor, often causing substantial damage to critical neuroendocrine structures such as the hypothalamus, pituitary gland, and optic apparatus. Paracrine signaling mechanisms driving tumor behavior have been hypothesized, with IL-6R overexpression identified as a potential therapeutic target. To identify potential novel therapies, we characterized inflammatory and immunomodulatory factors in ACP cyst fluid and solid tumor components...
September 1, 2017: Journal of Neuropathology and Experimental Neurology
https://www.readbyqxmd.com/read/28843847/skin-transcriptomes-of-common-bottlenose-dolphins-tursiops-truncatus-from-the-northern-gulf-of-mexico-and-southeastern-u-s-atlantic-coasts
#8
Marion G Neely, Jeanine S Morey, Paul Anderson, Brian C Balmer, Gina M Ylitalo, Eric S Zolman, Todd R Speakman, Carrie Sinclair, Melannie J Bachman, Kevin Huncik, John Kucklick, Patricia E Rosel, Keith D Mullin, Teri K Rowles, Lori H Schwacke, Frances M Van Dolah
Common bottlenose dolphins serve as sentinels for the health of their coastal environments as they are susceptible to health impacts from anthropogenic inputs through both direct exposure and food web magnification. Remote biopsy samples have been widely used to reveal contaminant burdens in free-ranging bottlenose dolphins, but do not address the health consequences of this exposure. To gain insight into whether remote biopsies can also identify health impacts associated with contaminant burdens, we employed RNA sequencing (RNA-seq) to interrogate the transcriptomes of remote skin biopsies from 116 bottlenose dolphins from the northern Gulf of Mexico and southeastern U...
August 23, 2017: Marine Genomics
https://www.readbyqxmd.com/read/28820376/influenza-a-h3n2-virus-in-swine-at-agricultural-fairs-and-transmission-to-humans-michigan-and-ohio-usa-2016
#9
Andrew S Bowman, Rasna R Walia, Jacqueline M Nolting, Amy L Vincent, Mary Lea Killian, Michele M Zentkovich, Joshua N Lorbach, Sarah E Lauterbach, Tavis K Anderson, C Todd Davis, Natosha Zanders, Joyce Jones, Yunho Jang, Brian Lynch, Marisela R Rodriguez, Lenee Blanton, Stephen E Lindstrom, David E Wentworth, John Schiltz, James J Averill, Tony Forshey
In 2016, a total of 18 human infections with influenza A(H3N2) virus occurred after exposure to influenza-infected swine at 7 agricultural fairs. Sixteen of these cases were the result of infection by a reassorted virus with increasing prevalence among US swine containing a hemagglutinin gene from 2010-11 human seasonal H3N2 strains.
September 2017: Emerging Infectious Diseases
https://www.readbyqxmd.com/read/28797570/genetic-variants-related-to-longer-telomere-length-are-associated-with-increased-risk-of-renal-cell-carcinoma
#10
Mitchell J Machiela, Jonathan N Hofmann, Robert Carreras-Torres, Kevin M Brown, Mattias Johansson, Zhaoming Wang, Matthieu Foll, Peng Li, Nathaniel Rothman, Sharon A Savage, Valerie Gaborieau, James D McKay, Yuanqing Ye, Marc Henrion, Fiona Bruinsma, Susan Jordan, Gianluca Severi, Kristian Hveem, Lars J Vatten, Tony Fletcher, Kvetoslava Koppova, Susanna C Larsson, Alicja Wolk, Rosamonde E Banks, Peter J Selby, Douglas F Easton, Paul Pharoah, Gabriella Andreotti, Laura E Beane Freeman, Stella Koutros, Demetrius Albanes, Satu Mannisto, Stephanie Weinstein, Peter E Clark, Todd E Edwards, Loren Lipworth, Susan M Gapstur, Victoria L Stevens, Hallie Carol, Matthew L Freedman, Mark M Pomerantz, Eunyoung Cho, Peter Kraft, Mark A Preston, Kathryn M Wilson, J Michael Gaziano, Howard S Sesso, Amanda Black, Neal D Freedman, Wen-Yi Huang, John G Anema, Richard J Kahnoski, Brian R Lane, Sabrina L Noyes, David Petillo, Leandro M Colli, Joshua N Sampson, Celine Besse, Helene Blanche, Anne Boland, Laurie Burdette, Egor Prokhortchouk, Konstantin G Skryabin, Meredith Yeager, Mirjana Mijuskovic, Miodrag Ognjanovic, Lenka Foretova, Ivana Holcatova, Vladimir Janout, Dana Mates, Anush Mukeriya, Stefan Rascu, David Zaridze, Vladimir Bencko, Cezary Cybulski, Eleonora Fabianova, Viorel Jinga, Jolanta Lissowska, Jan Lubinski, Marie Navratilova, Peter Rudnai, Neonila Szeszenia-Dabrowska, Simone Benhamou, Geraldine Cancel-Tassin, Olivier Cussenot, H Bas Bueno-de-Mesquita, Federico Canzian, Eric J Duell, Börje Ljungberg, Raviprakash T Sitaram, Ulrike Peters, Emily White, Garnet L Anderson, Lisa Johnson, Juhua Luo, Julie Buring, I-Min Lee, Wong-Ho Chow, Lee E Moore, Christopher Wood, Timothy Eisen, James Larkin, Toni K Choueiri, G Mark Lathrop, Bin Tean Teh, Jean-Francois Deleuze, Xifeng Wu, Richard S Houlston, Paul Brennan, Stephen J Chanock, Ghislaine Scelo, Mark P Purdue
BACKGROUND: Relative telomere length in peripheral blood leukocytes has been evaluated as a potential biomarker for renal cell carcinoma (RCC) risk in several studies, with conflicting findings. OBJECTIVE: We performed an analysis of genetic variants associated with leukocyte telomere length to assess the relationship between telomere length and RCC risk using Mendelian randomization, an approach unaffected by biases from temporal variability and reverse causation that might have affected earlier investigations...
November 2017: European Urology
https://www.readbyqxmd.com/read/28772032/differentiating-heart-failure-phenotypes-using-sex-specific-transcriptomic-and-proteomic-biomarker-panels
#11
Mustafa Toma, George J Mak, Virginia Chen, Zsuzsanna Hollander, Casey P Shannon, Karen K Y Lam, Raymond T Ng, Scott J Tebbutt, Janet E Wilson-McManus, Andrew Ignaszewski, Todd Anderson, Jason R B Dyck, Jonathan Howlett, Justin Ezekowitz, Bruce M McManus, Gavin Y Oudit
AIMS: Heart failure with preserved ejection fraction (HFpEF) accounts for 30-50% of patients with heart failure (HF). A major obstacle in HF management is the difficulty in differentiating between HFpEF and heart failure with reduced ejection fraction (HFrEF) using conventional clinical and laboratory investigations. The aim of this study is to develop robust transcriptomic and proteomic biomarker signatures that can differentiate HFpEF from HFrEF. METHODS AND RESULTS: A total of 210 HF patients were recruited in participating institutions from the Alberta HEART study...
August 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28741909/a-prospective-evaluation-of-the-established-criteria-for-heart-failure-with-preserved-ejection-fraction-using-the-alberta-heart-cohort
#12
Justin A Ezekowitz, Finlay A McAlister, Jonathan Howlett, Wendimagegn Alemayehu, Ian Paterson, Israel Belenkie, Gavin Y Oudit, Padma Kaul, Jason R Dyck, Todd Anderson
AIMS: Heart failure with a preserved ejection fraction (HF-PEF) remains a difficult clinical diagnosis. The aim of this study was to test the utility of established criteria to classify patients with HF-PEF. We prospectively enrolled patients into one of five groups across a spectrum of cardiac disease and applied three different criteria for HF-PEF and calculated diagnostic metrics. METHODS AND RESULTS: A total of 565 patients were included in the analysis, including 170 patients with an adjudicated diagnosis of HF-PEF, 152 patients with heart failure with reduced ejection fraction, 152 patients at risk for heart failure, and 91 age-matched healthy controls...
July 25, 2017: ESC Heart Failure
https://www.readbyqxmd.com/read/28735890/prognostic-validation-of-sky92-and-its-combination-with-iss-in-an-independent-cohort-of-patients-with-multiple-myeloma
#13
Erik H van Beers, Martin H van Vliet, Rowan Kuiper, Leonie de Best, Kenneth C Anderson, Ajai Chari, Sundar Jagannath, Andrzej Jakubowiak, Shaji K Kumar, Joan B Levy, Daniel Auclair, Sagar Lonial, Donna Reece, Paul Richardson, David S Siegel, A Keith Stewart, Suzanne Trudel, Ravi Vij, Todd M Zimmerman, Rafael Fonseca
BACKGROUND: High risk and low risk multiple myeloma patients follow a very different clinical course as reflected in their PFS and OS. To be clinically useful, methodologies used to identify high and low risk disease must be validated in representative independent clinical data and available so that patients can be managed appropriately. A recent analysis has indicated that SKY92 combined with the International Staging System (ISS) identifies patients with different risk disease with high sensitivity...
July 4, 2017: Clinical Lymphoma, Myeloma & Leukemia
https://www.readbyqxmd.com/read/28669702/incidence-and-prognostic-implications-of-late-bleeding-after-myocardial-infarction-or-unstable-angina-according-to-treatment-strategy
#14
Miriam Brinkert, Danielle A Southern, Matthew T James, Merrill L Knudtson, Todd J Anderson, François Charbonneau
BACKGROUND: Bleeding complications accompanying coronary revascularization are associated with increased mortality; however, few data are available on subsequent bleeding risk. We used administrative data to assess the incidence of late bleeding events in patients with acute coronary syndrome (ACS) according to treatment allocation. METHODS: The cohort and bleeding events were identified through the Canadian Institute for Health Information discharge abstract database...
August 2017: Canadian Journal of Cardiology
https://www.readbyqxmd.com/read/28669553/expert-consensus-guidelines-for-stocking-of-antidotes-in-hospitals-that-provide-emergency-care
#15
Richard C Dart, Lewis R Goldfrank, Brian L Erstad, David T Huang, Knox H Todd, Jeffrey Weitz, Vikhyat S Bebarta, E Martin Caravati, Fred M Henretig, Theodore R Delbridge, William Banner, Sandra M Schneider, Victoria E Anderson
We provide recommendations for stocking of antidotes used in emergency departments (EDs). An expert panel representing diverse perspectives (clinical pharmacology, medical toxicology, critical care medicine, hematology/oncology, hospital pharmacy, emergency medicine, emergency medical services, pediatric emergency medicine, pediatric critical care medicine, poison centers, hospital administration, and public health) was formed to create recommendations for antidote stocking. Using a standardized summary of the medical literature, the primary reviewer for each antidote proposed guidelines for antidote stocking to the full panel...
June 29, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/28653691/corrigendum-a-viral-strategy-for-targeting-and-manipulating-interneurons-across-vertebrate-species
#16
Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi, Lihua Guo, Qing Xu, Runpeng Liu, Congyi Lu, Jianhua Chu, Michael C Avery, Mohammad S Rashid, Myungin Baek, Amanda L Jacob, Gordon B Smith, Daniel E Wilson, Georg Kosche, Illya Kruglikov, Tomasz Rusielewicz, Vibhakar C Kotak, Todd M Mowery, Stewart A Anderson, Edward M Callaway, Jeremy S Dasen, David Fitzpatrick, Valentina Fossati, Michael A Long, Scott Noggle, John H Reynolds, Dan H Sanes, Bernardo Rudy, Guoping Feng, Gord Fishell
No abstract text is available yet for this article.
June 27, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28653689/addendum-a-viral-strategy-for-targeting-and-manipulating-interneurons-across-vertebrate-species
#17
Jordane Dimidschstein, Qian Chen, Robin Tremblay, Stephanie L Rogers, Giuseppe-Antonio Saldi, Lihua Guo, Qing Xu, Runpeng Liu, Congyi Lu, Jianhua Chu, Michael C Avery, Mohammad S Rashid, Myungin Baek, Amanda L Jacob, Gordon B Smith, Daniel E Wilson, Georg Kosche, Illya Kruglikov, Tomasz Rusielewicz, Vibhakar C Kotak, Todd M Mowery, Stewart A Anderson, Edward M Callaway, Jeremy S Dasen, David Fitzpatrick, Valentina Fossati, Michael A Long, Scott Noggle, John H Reynolds, Dan H Sanes, Bernardo Rudy, Guoping Feng, Gord Fishell
No abstract text is available yet for this article.
June 27, 2017: Nature Neuroscience
https://www.readbyqxmd.com/read/28598434/genome-wide-association-study-identifies-multiple-risk-loci-for-renal-cell-carcinoma
#18
Ghislaine Scelo, Mark P Purdue, Kevin M Brown, Mattias Johansson, Zhaoming Wang, Jeanette E Eckel-Passow, Yuanqing Ye, Jonathan N Hofmann, Jiyeon Choi, Matthieu Foll, Valerie Gaborieau, Mitchell J Machiela, Leandro M Colli, Peng Li, Joshua N Sampson, Behnoush Abedi-Ardekani, Celine Besse, Helene Blanche, Anne Boland, Laurie Burdette, Amelie Chabrier, Geoffroy Durand, Florence Le Calvez-Kelm, Egor Prokhortchouk, Nivonirina Robinot, Konstantin G Skryabin, Magdalena B Wozniak, Meredith Yeager, Gordana Basta-Jovanovic, Zoran Dzamic, Lenka Foretova, Ivana Holcatova, Vladimir Janout, Dana Mates, Anush Mukeriya, Stefan Rascu, David Zaridze, Vladimir Bencko, Cezary Cybulski, Eleonora Fabianova, Viorel Jinga, Jolanta Lissowska, Jan Lubinski, Marie Navratilova, Peter Rudnai, Neonila Szeszenia-Dabrowska, Simone Benhamou, Geraldine Cancel-Tassin, Olivier Cussenot, Laura Baglietto, Heiner Boeing, Kay-Tee Khaw, Elisabete Weiderpass, Borje Ljungberg, Raviprakash T Sitaram, Fiona Bruinsma, Susan J Jordan, Gianluca Severi, Ingrid Winship, Kristian Hveem, Lars J Vatten, Tony Fletcher, Kvetoslava Koppova, Susanna C Larsson, Alicja Wolk, Rosamonde E Banks, Peter J Selby, Douglas F Easton, Paul Pharoah, Gabriella Andreotti, Laura E Beane Freeman, Stella Koutros, Demetrius Albanes, Satu Männistö, Stephanie Weinstein, Peter E Clark, Todd L Edwards, Loren Lipworth, Susan M Gapstur, Victoria L Stevens, Hallie Carol, Matthew L Freedman, Mark M Pomerantz, Eunyoung Cho, Peter Kraft, Mark A Preston, Kathryn M Wilson, J Michael Gaziano, Howard D Sesso, Amanda Black, Neal D Freedman, Wen-Yi Huang, John G Anema, Richard J Kahnoski, Brian R Lane, Sabrina L Noyes, David Petillo, Bin Tean Teh, Ulrike Peters, Emily White, Garnet L Anderson, Lisa Johnson, Juhua Luo, Julie Buring, I-Min Lee, Wong-Ho Chow, Lee E Moore, Christopher Wood, Timothy Eisen, Marc Henrion, James Larkin, Poulami Barman, Bradley C Leibovich, Toni K Choueiri, G Mark Lathrop, Nathaniel Rothman, Jean-Francois Deleuze, James D McKay, Alexander S Parker, Xifeng Wu, Richard S Houlston, Paul Brennan, Stephen J Chanock
Previous genome-wide association studies (GWAS) have identified six risk loci for renal cell carcinoma (RCC). We conducted a meta-analysis of two new scans of 5,198 cases and 7,331 controls together with four existing scans, totalling 10,784 cases and 20,406 controls of European ancestry. Twenty-four loci were tested in an additional 3,182 cases and 6,301 controls. We confirm the six known RCC risk loci and identify seven new loci at 1p32.3 (rs4381241, P=3.1 × 10(-10)), 3p22.1 (rs67311347, P=2.5 × 10(-8)), 3q26...
June 9, 2017: Nature Communications
https://www.readbyqxmd.com/read/28570504/amanita-phalloides-mushroom-poisonings-northern-california-december-2016
#19
Kathy T Vo, Martha E Montgomery, S Todd Mitchell, Pieter H Scheerlinck, Daniel K Colby, Kathryn H Meier, Susan Kim-Katz, Ilene B Anderson, Steven R Offerman, Kent R Olson, Craig G Smollin
Amanita phalloides, colloquially known as the "death cap," belongs to the Phalloideae section of the Amanita family of mushrooms and is responsible for most deaths following ingestion of foraged mushrooms worldwide (1). On November 28, 2016, members of the Bay Area Mycological Society notified personnel at the California Poison Control System (CPCS) of an unusually large A. phalloides bloom in the greater San Francisco Bay Area, coincident with the abundant rainfall and recent warm weather. Five days later, CPCS received notification of the first human A...
June 2, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28525540/alcohol-consumption-and-common-carotid-intima-media-thickness-the-use-imt-study
#20
Annie R Britton, Diederick E Grobbee, Hester M den Ruijter, Todd J Anderson, Moise Desvarieux, Gunnar Engström, Greg W Evans, Bo Hedblad, Jussi Kauhanen, Sudhir Kurl, Eva M Lonn, Ellisiv B Mathiesen, Joseph F Polak, Jacqueline F Price, Christopher M Rembold, Maria Rosvall, Tatjana Rundek, Jukka T Salonen, Coen Stehouwer, Tomi-Pekka Tuomainen, Michiel L Bots
Aims: Epidemiological evidence indicates a protective effect of light to moderate alcohol consumption compared to non-drinking and heavy drinking. Although several mechanisms have been suggested, the effect of alcohol on atherosclerotic changes in vessel walls is unclear. Therefore, we explored the relationship between alcohol consumption and common carotid intima media thickness, a marker of early atherosclerosis in the general population. Methods: Individual participant data from eight cohorts, involving 37,494 individuals from the USE-IMT collaboration were used...
July 1, 2017: Alcohol and Alcoholism: International Journal of the Medical Council on Alcoholism
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