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Grace Anne Thompson, Larry Allen Abel
Children on the autism spectrum are reported to have lower rates of social gaze as early as toddlerhood, and this pattern persists across the lifespan. Finding ways to promote more natural and spontaneous engagement in social interactions may help to boost developmental opportunities in the child's home and community settings. This proof-of-concept study hypothesized that a video of a singer would elicit more attention to the performer, particularly to her face, than a video of her reading a story, and that the child's familiarity with the material would enhance attention...
January 22, 2018: Autism Research: Official Journal of the International Society for Autism Research
Qiang Du, Ruofei Yu, Han Wang, Dong Yan, Qi Yuan, Yixin Ma, Dennis Slamon, Dongmei Hou, Huiling Wang, Qi Wang
OBJECTIVES: Autoantibodies tumor-associated antigens (TAAs) could be a valuable tool for the diagnosis or early detection of cancer due to their relatively high specificity and stability. The purpose of this study is to detect the level of tumor-associated autoantibodies in lung cancer and assess the diagnostic potential of autoantibodies in screening strategy for early stage lung cancer. MATERIALS AND METHODS: Levels of tumor-associated autoantibodies (AAbs) were measured against a panel of seven tumor-associated antigens (p53, PGP9...
January 22, 2018: Clinical Respiratory Journal
Sai-Hung Tang, Oi-I Chio, Ling-Hui Chang, Hui-Fen Mao, Li-Hua Chen, Ping-Keung Yip, Jen-Ping Hwang
AIM: To determine whether giving dementia caregivers active psychoeducational intervention is more efficacious than passive intervention for improving their caregiving skills and reducing their caregiving burden. METHODS: This study was a prospective, single-blinded, controlled trial with 43 caregiver/person-with-dementia dyads. The dyads were randomly assigned to the active psychoeducational intervention (AP) group, which used role-play, discussion, and development of problem-solving capacity to build up their caregiving skills and competence, or the passive psychoeducational intervention (PP) group, which gave caregivers educational materials on common caregiving strategies...
January 22, 2018: Geriatrics & Gerontology International
Noelle M Cocoros, Anne Gulbech Ording, Erzsébet Horváth-Puhó, Victor W Henderson, Henrik Toft Sørensen
BACKGROUND: Substantial but inconclusive evidence suggests in utero exposure to influenza infection may be linked with Alzheimer's disease. OBJECTIVES: We examined whether individuals exposed in utero to the 1918 influenza pandemic are at increased risk of dementia. PATIENTS/METHODS: In this cohort study, surveillance data were used to identify months when influenza activity was at its peak during the pandemic. Using birth dates, exposed and unexposed individuals were identified based on whether they were in utero during ≥1 of the peak months...
January 22, 2018: Influenza and Other Respiratory Viruses
Li-Qiong Shen, Xiao-Ying Zang, Ji-Yan Cong
BACKGROUND: Personal digital assistants, technology with various functions, have been applied in international clinical practice. Great benefits in reducing medical errors and enhancing the efficiency of clinical work have been achieved, but little research has investigated nurses' satisfaction with the use of personal digital assistants. AIM: To investigate nurses' satisfaction with use of personal digital assistants, and to explore the predictors of this. DESIGN: This is a cross-sectional descriptive study...
January 21, 2018: International Journal of Nursing Practice
Rodolfo Savica, Brandon R Grossardt, Walter A Rocca, James H Bower
BACKGROUND: Limited population-based information is available on the co-occurrence of dementia and PD. However, projecting the prevalence of PD with and without dementia during the next 50 years is crucial for planning public-health and patient-care initiatives. OBJECTIVES: The objective of this study was to project the prevalence of PD with and without dementia in the United States by 2060. METHODS: We used the Rochester Epidemiology Project medical records-linkage system to identify all persons with PD with or without dementia residing in Olmsted County, Minnesota, on January 1, 2006...
January 22, 2018: Movement Disorders: Official Journal of the Movement Disorder Society
Song Hee Han, Hye In Cheon, Min Seok Hur, Min Jung Kim, Won Hee Jung, Yang Won Lee, Yong Beom Choe, Kyu Joong Ahn
With the recent availability of culture-independent sequencing methods, studies have been conducted to analyze skin microorganisms present in patients with atopic dermatitis (AD). However, the database on the skin fungal communities, "mycobiome," has been relatively restrictive compared with the bacterial world. We aimed to comparatively analyze the overall skin mycobiome between patients with AD and healthy individuals in the Korean population. We analyzed skin swab samples obtained from the antecubital fossae of 8 patients with AD and 8 healthy controls...
January 21, 2018: Experimental Dermatology
Kenneth Hugdahl
In this article I have summarized some of the main trends and topics of my research career, spanning a time period of 50 years, from its start as a master student at the Department of Psychology, University of Uppsala, Sweden to seeing the end of a long career, now at the University of Bergen, Norway. This journey has, apart from having been a journey across various disciplines and topics in experimental psychology, psychophysiology and neuropsychology, functional neuroimaging and cognitive neuroscience, also been a social class journey for me personally...
February 2018: Scandinavian Journal of Psychology
Moti Freiman, Hannes Nickisch, Holger Schmitt, Pál Maurovich-Horvat, Patrick M Donnelly, Mani Vembar, Liran Goshen
PURPOSE: The purpose of this study is to develop and evaluate a functionally personalized boundary condition (BC) model for estimating the fractional flow reserve (FFR) from coronary computed tomography angiography (CCTA) using flow simulation (CT-FFR). MATERIALS AND METHODS: CCTA data of 90 subjects with subsequent invasive FFR in 123 lesions within 21 days (range: 0-83) were retrospectively collected. We developed a functionally-personalized BC model accounting specifically for the coronary micro-vascular resistance dependency on the coronary outlets pressure suggested by several physiological studies...
January 22, 2018: Medical Physics
Saki Narita, Eiko Saito, Norie Sawada, Taichi Shimazu, Taiki Yamaji, Motoki Iwasaki, Junko Ishihara, Ribeka Takachi, Kenji Shibuya, Manami Inoue, Shoichiro Tsugane
While many epidemiological studies have studied the association between lung cancer risk and fruits and vegetable consumption, the major sources of antioxidant vitamins, only a few have investigated the direct association with antioxidants in consideration of cancer subtypes and smoking status. Here, we examined the association between consumption of antioxidant vitamins and lung cancer risk in one of the largest prospective cohort studies in Japan. We investigated the association of dietary antioxidant vitamins intake, namely retinol, vitamin C, vitamin E, α-carotene, and β-carotene, and subsequent incidence of lung cancer among 38,207 men and 41,498 women in the Japan Public Health Center-based Prospective Study...
January 22, 2018: International Journal of Cancer. Journal International du Cancer
Liza Behrens, Kimberly Van Haitsma, Jennifer Brush, Marie Boltz, Donna Volpe, Ann Marie Kolanowksi
Delivering person-centered care (PCC) is no longer an option for nursing homes (NH) that receive funding from the Centers for Medicare & Medicaid Services. NH staff need evidence-based protocols to guide efforts in honoring preferred choices of residents, especially those that are perceived to be risky. The Rothschild Care Planning Process for Resident Choice was created to honor such choices. The current article provides a case exemplar to demonstrate the use of the Rothschild Care Planning Process for Resident Choice with one NH resident who was perceived by staff to be making a risky choice...
January 16, 2018: Journal of Gerontological Nursing
Robert S Ohgami, Andreas Rosenwald, Adam Bagg
This commentary highlights the article by Hung et al that details the design and implementation of a 32-gene next-generation sequencing (NGS) panel for lymphomas, and compares hybrid-capture versus amplicon-based NGS approaches.
January 18, 2018: Journal of Molecular Diagnostics: JMD
Minna Torniainen-Holm, Jaana Suvisaari, Maija Lindgren, Tommi Härkänen, Faith Dickerson, Robert H Yolken
BACKGROUND: Earlier studies have documented an association between cytomegalovirus and cognitive impairment, but results have been inconsistent. Few studies have investigated the association of cytomegalovirus and Epstein-Barr virus with cognitive decline longitudinally. Our aim was to examine whether cytomegalovirus and Epstein-Barr virus are associated with cognitive decline in adults METHOD: The study sample is from the Finnish Health 2000 Survey (BRIF8901, n = 7112), which is representative of the Finnish adult population...
January 16, 2018: Brain, Behavior, and Immunity
J Hardy, T C Veinot, X Yan, V J Berrocal, P Clarke, R Goodspeed, I N Gomez, D Romero, V G V Vydiswaran
Research regarding place and health has undergone a revolution due to the availability of consumer-focused location-tracking devices that reveal fine-grained details of human mobility. Such research requires that participants accept such devices enough to use them in their daily lives. There is a need for a theoretically grounded understanding of acceptance of different location-tracking technology options, and its research implications. Guided by an extended Unified Theory of Acceptance and Use of Technology (UTAUT), we conducted a 28-day field study comparing 21 chronically ill people's acceptance of two leading, consumer-focused location-tracking technologies deployed for research purposes: 1) a location-enabled smartphone, and 2) a GPS watch/activity tracker...
January 17, 2018: Journal of Biomedical Informatics
Byung-Han Ryu, Ji Yeun Kim, Taeeun Kim, Min-Chul Kim, Min Jae Kim, Yong-Phil Chong, Sang-Oh Lee, Sang-Ho Choi, Yang Soo Kim, Jun Hee Woo, Sung-Han Kim
OBJECTIVES: Severe fever with thrombocytopenia syndrome (SFTS) is an emerging tick-borne disease in Korea and China. Although there is previous evidence of person-to-person transmission via direct contact with body fluids, the role of environmental contamination by SFTS virus (SFTSV) in healthcare settings has not been established. We therefore investigated the contamination of the healthcare environment by SFTSV. METHODS: We investigated the possible contamination of hospital air and surfaces with SFTSV transmission by collecting air and swabbing environmental surface samples in 2 hospitals treating 6 SFTS patients between March and September 2017...
January 17, 2018: Clinical Microbiology and Infection
Eirini Flouri, Martina K Narayanan, Ane Nærde
BACKGROUND: Parents of young children generally report more depressive symptoms than parents of adult children or people without children, mainly because the presence of young children increases exposure to significant stressors (such as stressful life events). However, most studies on the depressogenic role of stressful life events in parents of young children have focussed on mothers. METHODS: Using data from 1138 families with young children in Norway, we investigated gender differences in the effect of stressful life events after a child's birth on the development of parental depressive symptoms in 3 follow-ups at child's ages 3-6 years...
January 3, 2018: Journal of Affective Disorders
Gerd Wagner, Annegret Krause-Utz, Feliberto de la Cruz, Andy Schumann, Christian Schmahl, Karl-Jürgen Bär
Impulsive behavior, difficulties in controlling anger and suicidal behavior are typical patterns of affective/behavioral dysregulation in patients with borderline personality disorder (BPD). Previous functional MRI studies in the resting state condition demonstrated altered functional connectivity (FC) between the anterior cingulate cortex (ACC) and the frontoparietal executive control network (ECN), which was significantly associated with impulsivity in BPD. Impulsivity is often defined as a function of inhibitory control, strongly relying on the proper functioning of the fronto-cingulo-striatal network...
January 17, 2018: Progress in Neuro-psychopharmacology & Biological Psychiatry
Todd A Astorino, Noelle Bediamol, Sarah Cotoia, Kenneth Ines, Nicolas Koeu, Natasha Menard, Brianna Nyugen, Cassandra Olivo, Gabrielle Phillips, Ardreen Tirados, Gabriela Velasco Cruz
CONTEXT/OBJECTIVE: Maximal oxygen uptake (VO2max) is a widely used measure of cardiorespiratory fitness, aerobic function, and overall health risk. Although VO2max has been measured for almost 100 yr, no standardized criteria exist to verify VO2max attainment. Studies document that incidence of 'true' VO2max obtained from incremental exercise (INC) can be confirmed using a subsequent verification test (VER). In this study, we examined efficacy of VER in persons with spinal cord injury (SCI)...
January 22, 2018: Journal of Spinal Cord Medicine
S Llamas-Velasco, A García-Redondo, A Herrero-San Martín, V Puertas Martín, M González-Sánchez, D A Pérez-Martínez, A Villarejo-Galende
We present a 86-year-old woman without relevant medical history and two brothers who died by dementia, who started at 55 years with depression and personality changes with ongoing worsening (>30 years) and functional decline. Screening dementia blood test and brain magnetic resonance imaging did not show results that pointed to a secondary cause. The patient met the diagnostic criteria for possible behavioral frontotemporal dementia with a slow progression (bvFTD-SP), suggesting a benign variant. A genetic study confirmed a C9ORF72 hexanucleotide expansion, making this the sixth case mentioned in the literature...
January 22, 2018: Neurocase
Bronwyn Hemsley, Stuart Palmer, Stephen Dann, Susan Balandin
PURPOSE: Articles 19, 26 and 27 of the Universal Declaration of Human Rights and Articles 4, 9 and 21 of the Convention on the Rights of Persons with Disabilities promote the human rights of communication, education, use of technology and access to information. Social media is an important form of online communication, and Twitter increases users' visibility, influence and reach online. The aim of this sociotechnical research was to determine the impact of teaching three people who use Augmentative and Alternative Communication (AAC) to use Twitter...
January 22, 2018: International Journal of Speech-language Pathology
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