keyword
MENU ▼
Read by QxMD icon Read
search

Law and ethics

keyword
https://www.readbyqxmd.com/read/29346210/significance-errors-power-and-sample-size-the-blocking-and-tackling-of-statistics
#1
Edward J Mascha, Thomas R Vetter
Inferential statistics relies heavily on the central limit theorem and the related law of large numbers. According to the central limit theorem, regardless of the distribution of the source population, a sample estimate of that population will have a normal distribution, but only if the sample is large enough. The related law of large numbers holds that the central limit theorem is valid as random samples become large enough, usually defined as an n ≥ 30. In research-related hypothesis testing, the term "statistically significant" is used to describe when an observed difference or association has met a certain threshold...
February 2018: Anesthesia and Analgesia
https://www.readbyqxmd.com/read/29343181/experiencing-abortion-rights-in-india-through-issues-of-autonomy-and-legality-a-few-controversies
#2
Tulsi Patel
Abortion laws in India, like other laws, are premised on the 1861 British Penal Code. The Medical Termination of Pregnancy Act was passed in 1971 to circumvent the criminality clause around abortion. Yet the law continues to render invisible women's right to choose. Legal procedures have often hindered in permitting abortion, resulting in the death of a mother or the foetus. Despite the latest techno-medical advances, the laws have remained stagnant or rather restrictive, complicated further by selective female foetus abortions...
January 17, 2018: Global Public Health
https://www.readbyqxmd.com/read/29325614/ethical-issues-in-neurogenetics
#3
Wendy R Uhlmann, J Scott Roberts
Many neurogenetic conditions are inherited and therefore diagnosis of a patient will have implications for the patient's relatives and can raise ethical issues. Predictive genetic testing offers asymptomatic relatives the opportunity to determine their risk status for a neurogenetic condition, and professional guidelines emphasize patients' autonomy and informed, voluntary decision making. Beneficence and nonmaleficence both need to be considered when making decisions about disclosure and nondisclosure of genetic information and test results...
2018: Handbook of Clinical Neurology
https://www.readbyqxmd.com/read/29306873/a-critical-review-of-conscientious-objection-and-decriminalisation-of-abortion-in-chile
#4
Adela Montero, Raúl Villarroel
From 1989 through September 2017, Chile's highly restrictive abortion laws exposed women to victimisation and needlessly threatened their health, freedom and even lives. However, after decades of unsuccessful attempts to decriminalise abortion, legislation regulating pregnancy termination on three grounds was recently enacted. In the aftermath, an aggressive conservative drive designed to turn conscientious objection into a pivotal new obstacle, mounted during the congressional debate, has led to extensive, complex arguments about the validity and legitimacy of conscientious objection...
January 6, 2018: Journal of Medical Ethics
https://www.readbyqxmd.com/read/29298745/-animal-ethics-in-the-19th-century-and-swiss-animal-protection-law
#5
I Bloch
The development of animal ethics and animal rights from the antiquity up to modern times is described. The relationship of humans to animals was primarily based on fear and animal cult, developed by the domestication to a partnership. The philosophers of the early modern age denied the animals the reason, what was disadvantageous to the position of the animals in the society and the behavior of humans to the animals. By the end of the 19th century the animal protection concept developed with numerous postulates for legal regulations...
January 2018: Schweizer Archiv Für Tierheilkunde
https://www.readbyqxmd.com/read/29298727/mandatory-vaccination-understanding-the-common-good-in-the-midst-of-the-global-polio-eradication-campaign
#6
Lawrence O Gostin
BACKGROUND: The detection of wild poliovirus in Israeli sewage in May 2013 led the health authorities to vaccinate children with OPV (Oral Polio Vaccine). Shelly Kamin-Friedman explored the legal and ethical dimensions of this policy. This commentary makes three claims: (1) Mandatory vaccination is a valid exercise of the state's police powers to protect the common good. (2) A disease eradication campaign is a sufficient ground for the exercise of those powers. (3) The state is obliged to use the least restrictive/invasive measure to achieve community-wide vaccine coverage, but need not use less effective measures; further, determining which measure is most effective is a fact-specific determination...
January 3, 2018: Israel Journal of Health Policy Research
https://www.readbyqxmd.com/read/29296016/systematic-heterogenization-for-better-reproducibility-in-animal-experimentation
#7
S Helene Richter
The scientific literature is full of articles discussing poor reproducibility of findings from animal experiments as well as failures to translate results from preclinical animal studies to clinical trials in humans. Critics even go so far as to talk about a "reproducibility crisis" in the life sciences, a novel headword that increasingly finds its way into numerous high-impact journals. Viewed from a cynical perspective, Fett's law of the lab "Never replicate a successful experiment" has thus taken on a completely new meaning...
August 31, 2017: Lab Animal
https://www.readbyqxmd.com/read/29282423/establishment-of-medical-education-upon-internalization-of-virtue-ethics-bridging-the-gap-between-theory-and-practice
#8
Mansoureh Madani, Bagher Larijani, Ensieh Madani, Nazafarin Ghasemzadeh
During medical training, students obtain enough skills and knowledge. However, medical ethics accomplishes its goals when, together with training medical courses, it guides students behavior towards morality so that ethics-oriented medical practice is internalized. Medical ethics is a branch of applied ethics which tries to introduce ethics into physicians' practice and ethical decisions; thus, it necessitates the behavior to be ethical. Therefore, when students are being trained, they need to be supplied with those guidelines which turn ethical instructions into practice to the extent possible...
2017: Journal of Medical Ethics and History of Medicine
https://www.readbyqxmd.com/read/29259532/gene-editing-in-humans-towards-a-global-and-inclusive-debate-for-responsible-research%C3%A2
#9
Itziar de Lecuona, María Casado, Gemma Marfany, Manuel Lopez Baroni, Mar Escarrabill
In December 2016, the Opinion Group of the Bioethics and Law Observatory (OBD) of the University of Barcelona launched a Declaration on Bioethics and Gene Editing in Humans analyzing the use of genome editing techniques and their social, ethical, and legal implications through a multidisciplinary approach. It focuses on CRISPR/Cas9, a genome modification technique that enables researchers to edit specific sections of the DNA sequence of humans and other living beings. This technique has generated expectations and worries that deserve an interdisciplinary analysis and an informed social debate...
December 2017: Yale Journal of Biology and Medicine
https://www.readbyqxmd.com/read/29258513/systems-healthcare-a-holistic-paradigm-for-tomorrow
#10
REVIEW
Massimo S Fiandaca, Mark Mapstone, Elenora Connors, Mireille Jacobson, Edwin S Monuki, Shaista Malik, Fabio Macciardi, Howard J Federoff
Systems healthcare is a holistic approach to health premised on systems biology and medicine. The approach integrates data from molecules, cells, organs, the individual, families, communities, and the natural and man-made environment. Both extrinsic and intrinsic influences constantly challenge the biological networks associated with wellness. Such influences may dysregulate networks and allow pathobiology to evolve, resulting in early clinical presentation that requires astute assessment and timely intervention for successful mitigation...
December 19, 2017: BMC Systems Biology
https://www.readbyqxmd.com/read/29249912/paying-research-participants-regulatory-uncertainty-conceptual-confusion-and-a-path-forward
#11
Emily A Largent, Holly Fernandez Lynch
The practice of offering payment to individuals in exchange for their participation in clinical research is widespread and longstanding. Nevertheless, such payment remains the source of substantial debate, in particular about whether or the extent to which offers of payment coerce and/or unduly induce individuals to participate. Yet, the various laws, regulations, and ethical guidelines that govern the conduct of human subjects research offer relatively little in the way of specific guidance regarding what makes a payment offer ethically acceptable-or not...
2017: Yale Journal of Health Policy, Law, and Ethics
https://www.readbyqxmd.com/read/29248989/stratified-prevention-opportunities-and-limitations-report-on-the-1st-interdisciplinary-cardiovascular-workshop-in-augsburg
#12
Gregor Kirchhof, Josef Franz Lindner, Stephan Achenbach, Klaus Berger, Stefan Blankenberg, Heiner Fangerau, Henner Gimpel, Ulrich M Gassner, Jens Kersten, Dorothea Magnus, Herbert Rebscher, Heribert Schunkert, Stephan Rixen, Paulus Kirchhof
Sufficient exercise and sleep, a balanced diet, moderate alcohol consumption and a good approach to handle stress have been known as lifestyles that protect health and longevity since the Middle Age. This traditional prevention quintet, turned into a sextet by smoking cessation, has been the basis of the "preventive personality" that formed in the twentieth century. Recent analyses of big data sets including genomic and physiological measurements have unleashed novel opportunities to estimate individual health risks with unprecedented accuracy, allowing to target preventive interventions to persons at high risk and at the same time to spare those in whom preventive measures may not be needed or even be harmful...
December 16, 2017: Clinical Research in Cardiology: Official Journal of the German Cardiac Society
https://www.readbyqxmd.com/read/29243472/preliminary-ethical-appraisal-of-a-trial-what-s-it-all-about
#13
Helena Siipi
Preliminary ethical appraisal of medical trials is often based on the following four principles: respect for autonomy, beneficence, non-maleficence, and justice. Preliminary ethical appraisal should, however, not be understood solely as application of these four principles to practice. Ethical committees will inevitably interpret the principles and make decisions about their reciprocal importance in connection with each trial. Reasoning does not always proceed from above towards practical recommendations of action, but can instead also be based on a moral rule or practice relating to a certain action...
2017: Duodecim; Lääketieteellinen Aikakauskirja
https://www.readbyqxmd.com/read/29240046/what-is-the-origin-of-the-italian-term-medico-competente
#14
Michele Augusto Riva, Francesco Carnevale
BACKGROUND: The meaning of the term "medico competente" - usually adopted in Italy to indicate the occupational physician - is little known. OBJECTIVES: To describe the origins of the word "medico competente" in Italy. METHODS: We conducted a comprehensive analysis of the Italian legislation from the end of the nineteenth century to the present day. RESULTS: In the United Kingdom, occupational physicians were originally named as "certifying surgeon" (1833) and "appointed surgeon" (1860)...
December 14, 2017: La Medicina del Lavoro
https://www.readbyqxmd.com/read/29236230/gene-patents-in-canada-is-there-a-new-legal-landscape
#15
Katherine L Bonter, Carmela De Luca, Christi J Guerrini
In 2016, the Children's Hospital of Eastern Ontario (CHEO) announced the settlement of its patent lawsuit against US-based Transgenomic, Inc. At issue in the case was CHEO's ability to test for gene mutations associated with long QT syndrome (LQTS) that are described in Transgenomic's patents. CHEO challenged the patents as invalid, and Transgenomic ultimately agreed to license them on a royalty-free basis to CHEO and other healthcare institutions for LQTS testing and research. While widely celebrated in the media, the ethical rhetoric surrounding the settlement has at times obscured the practical and legal context in which it was made and will operate...
December 13, 2017: Molecular Diagnosis & Therapy
https://www.readbyqxmd.com/read/29233273/a-qualitative-analysis-of-student-written-law-and-ethics-cases-a-snapshot-of-py2-student-experience
#16
Tanya E Karwaki, Thomas K Hazlet
INTRODUCTION: This study was designed to better understand pharmacy students' experiences and recognition of legal and ethical tensions existing in pharmacy practice as demonstrated in student-written law and ethics cases. METHODS: A qualitative analysis of 132 student-written cases representing the team efforts of 1053 students over a 12-year time period was conducted. Student-written cases were coded and analyzed thematically. RESULTS: Our results demonstrate the types of ethical and legal issues our students have experienced in pharmacy practice during the first five quarters of their professional education...
May 2017: Currents in Pharmacy Teaching & Learning
https://www.readbyqxmd.com/read/29230696/an-exploration-of-the-protective-effects-of-investigators-ethical-awareness-upon-subjects-of-drug-clinical-trials-in-china
#17
L Zhang, X X Huang, H F Chen
Up till now, China has not enacted any legal mechanisms governing certification or supervision for ethics committees. This article analyses deficiencies in the protection of subjects in clinical drug trials under China's current laws and regulations; it emphasizes that investigators, as practitioners who have direct contact with subjects, play significant roles in protecting and safeguarding subjects' rights and interests. The paper compares the status quo in China in this area to that of other countries and discusses ways China might enhance the protection of rights and interests of trial subjects, such as enhancing the ethical awareness of investigators through training, improving laws and regulations, and strengthening the communication between investigators and ethics committees...
December 11, 2017: Journal of Bioethical Inquiry
https://www.readbyqxmd.com/read/29221846/prevailing-ethical-dilemmas-encountered-by-physicians-in-terminal-cancer-care-changed-after-the-enactment-of-the-natural-death-act-fifteen-years-follow-up-survey
#18
Hsien-Liang Huang, Chien-An Yao, Wen-Yu Hu, Shao-Yi Cheng, Shinn-Jang Huang, Chih-Dao Chen, Wen-Yuan Lin, Yen-Chun Lin, Tai-Yuan Chiu
CONTEXT: Advance directive laws have influences on ethical dilemmas encountered by physicians caring for terminal cancer patients. OBJECTIVES: To identify the prevailing ethical dilemmas among terminal care physicians fifteen years after the Natural Death Act was enacted in Taiwan. METHODS: This study is a cross-sectional survey from April 2014 to February 2015 using the clustering sampling method and a well-structured questionnaire. Targeted participants included physicians at oncology and related wards or palliative care units where terminal cancer care may be provided in Taiwan...
December 5, 2017: Journal of Pain and Symptom Management
https://www.readbyqxmd.com/read/29221536/exploration-of-global-health-careers-across-the-medical-fields
#19
Ernest Barthélemy, Vanessa Mallol, Alisse Hannaford, Christian Pean, Rehema Kutua, Christopher de Haydu, Natasha Anandaraja, Ramin Asgary, Ebrahim Elahi, Braden Hexom, Philip Landrigan, Taraneh Shirazian, Craig Katz
BACKGROUND: Despite expansion of interest among American medical students in global health (GH), academic medical centers face multiple obstacles to the development of structured GH curricula and career guidance. To meet these demands we sought to provide a systematic analysis of the accounts of GH experts. METHODS: We developed a collaborative, interview-based, qualitative analysis of GH experiences across six career-related themes that are relevant to medical students interested in GH: justification, medical education, economics, research prospects, law and ethics, and work-life balance...
May 2017: Annals of Global Health
https://www.readbyqxmd.com/read/29214967/fear-of-life-fear-of-death-and-fear-of-causing-death-how-legislative-changes-on-assisted-dying-are-doomed-to-fail
#20
Matti Häyry
Fear of life, fear of death, and fear of causing death form a combination that prevents reasoned changes in laws concerning end-of-life situations. This is shown systematically in this article using the methods of conceptual analysis. Prevalent fears are explicated and interpreted to see how their meanings differ depending on the chosen normative stance. When the meanings have been clarified, the impact of the fears on the motivations and justifications of potential legislative reforms are assessed. Two main normative stances are evoked...
January 2018: Cambridge Quarterly of Healthcare Ethics: CQ: the International Journal of Healthcare Ethics Committees
keyword
keyword
64171
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"