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Tinnitus treatment

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https://www.readbyqxmd.com/read/29150051/glutamate-is-down-regulated-and-tinnitus-loudness-levels-decreased-following-rtms-over-auditory-cortex-of-the-left-hemisphere-a-prospective-randomized-single-blinded-sham-controlled-cross-over-study
#1
Anthony T Cacace, Jiani Hu, Stephen Romero, Yang Xuan, Robert F Burkard, Richard S Tyler
Using a prospective randomized single-blinded sham-controlled cross-over design, we studied the efficacy of low frequency (1-Hz) repetitive transcranial magnetic stimulation (rTMS) over auditory cortex of the left temporal lobe as an experimental treatment modality for noise-induced tinnitus. Pre/post outcome measures for sham vs. active rTMS conditions included differential changes in tinnitus loudness, self-perceived changes in the Tinnitus Handicap Questionnaire (THQ), and neurochemical changes of brain metabolite concentrations using single voxel proton magnetic resonance spectroscopy ((1)H-MRS) obtained from left and right auditory cortical areas...
November 14, 2017: Hearing Research
https://www.readbyqxmd.com/read/29149379/efficacy-of-systemic-and-intratympanic-corticosteroid-combination-therapy-versus-intratympanic-or-systemic-therapy-in-patients-with-idiopathic-sudden-sensorineural-hearing-loss-a-randomized-controlled-trial
#2
Mohammadtaghi Khorsandi Ashtiani, Farzad Firouzi, Shahin Bastaninejad, Sasan Dabiri, Sevil Nasirmohtaram, Niloufar Saeedi, Hossein Ghazavi, Leyla Sahebi
OBJECTIVE: The present study was conducted to compare the rates of recovery from idiopathic sudden deafness after the treatment with oral and intratympanic corticosteroids in both mono and combination therapies. STUDY DESIGN: Triple-blind randomized clinical trial. SETTINGS: Tertiary referral hospital. SUBJECTS AND METHODS: A total of 112 patients who were admitted to the ENT emergency department randomly divided into three groups: an oral corticosteroid plus intratympanic placebo (systemic corticosteroid monotherapy group); an intratympanic corticosteroid plus oral placebo group (IT monotherapy group); and a combination therapy group (IT plus systemic combination group)...
November 17, 2017: European Archives of Oto-rhino-laryngology
https://www.readbyqxmd.com/read/29146645/logistic-regression-analysis-of-factors-influencing-the-effectiveness-of-intensive-sound-masking-therapy-in-patients-with-tinnitus
#3
Yuexin Cai, Qian Zhou, Haidi Yang, Jiajia Jiang, Fei Zhao, Xiayin Huang, Hanjie Mo, Xiaoting Chen, Hao Xiong, Suijun Chen, Xueyuan Zhang, Yiqing Zheng
OBJECTIVES: To investigate factors influencing the effectiveness of intensive sound masking therapy on tinnitus using logistic regression analysis. DESIGN: The study used a retrospective cross-section analysis. PARTICIPANTS: 102 patients with tinnitus were recruited at the Sun Yat-sen Memorial Hospital of Sun Yat-sen University, China. INTERVENTION: Intensive sound masking therapy was used as an intervention approach for patients with tinnitus...
November 15, 2017: BMJ Open
https://www.readbyqxmd.com/read/29143096/-neurofeedback-for-the-treatment-of-chronic-tinnitus-review-and-future-perspectives
#4
REVIEW
T Kleinjung, C Thüring, D Güntensperger, P Neff, M Meyer
Neurofeedback is a noninvasive neuromodulation technique employing real-time display of brain activity in terms of electroencephalography (EEG) signals to teach self-regulation of distinct patterns of brain activity or influence brain activity in a targeted manner. The benefit of this approach for control of symptoms in attention deficit disorders, hyperactivity, depression, and migraine has been proven. Studies in recent years have also repeatedly shown this treatment to improve tinnitus symptoms, although it has not become established as routine therapy...
November 15, 2017: HNO
https://www.readbyqxmd.com/read/29135862/management-of-sigmoid-sinus-associated-pulsatile-tinnitus-a-systematic-review-of-the-literature
#5
Alan C Wang, Avery N Nelson, Cassandra Pino, Peter F Svider, Robert S Hong, Eleanor Chan
OBJECTIVES: Although studies demonstrate 4 to 20% of patients with pulsatile tinnitus (PT) have associated sigmoid sinus anomalies, no consensus exists regarding optimal management. Our objective was to perform a systematic review exploring surgical and endovascular intervention of PT caused by sigmoid sinus anomalies. DATA SOURCES/EXTRACTION: A systematic review was performed using the Preferred Reporting Systems for Systematic Reviews and Meta-Analysis guidelines for reporting of results, with a target population encompassing patients with PT and either sigmoid sinus diverticulum or sigmoid wall dehiscence...
December 2017: Otology & Neurotology
https://www.readbyqxmd.com/read/29133012/tinnitus-related-fear-mediating-the-effects-of-a-cognitive-behavioural-specialised-tinnitus-treatment
#6
Rilana F F Cima, Gerard van Breukelen, Johan W S Vlaeyen
OBJECTIVE: Cognitive behavioural treatments (CBT) for the reduction of tinnitus complaints have been shown to be effective; however the specific mechanisms of change are yet to be unveiled. Reductions in tinnitus-related fear have been indicated to be an important factor in alleviating tinnitus suffering. The role of tinnitus-related fear has been proposed as a mediator explaining the cognitive behavioural treatment effects on tinnitus severity, tinnitus-related impairment and general quality of life of tinnitus patients...
October 12, 2017: Hearing Research
https://www.readbyqxmd.com/read/29131084/mindfulness-based-cognitive-therapy-as-a-treatment-for-chronic-tinnitus-a-randomized-controlled-trial
#7
Laurence McKenna, Elizabeth M Marks, Christopher A Hallsworth, Roland Schaette
BACKGROUND: Tinnitus is experienced by up to 15% of the population and can lead to significant disability and distress. There is rarely a medical or surgical target and psychological therapies are recommended. We investigated whether mindfulness-based cognitive therapy (MBCT) could offer an effective new therapy for tinnitus. METHODS: This single-site randomized controlled trial compared MBCT to intensive relaxation training (RT) for chronic, distressing tinnitus in adults...
November 3, 2017: Psychotherapy and Psychosomatics
https://www.readbyqxmd.com/read/29130671/-clinical-study-on-the-correlation-between-tinnitus-and-hearing-loss-in-400-patients
#8
Jun-Nan An, Yun Zheng
OBJECTIVE: To investigate the correlation between tinnitus and hearing loss. METHODS: Clinical data of 400 patients presented with tinnitus as the first chief complain were analyzed. The relationship between tinnitus and hearing loss was categorized based on sites,onset time of tinnitus and hearing loss,for the purpose of provideing clinical evidence to explore the etiology,treatment and prognosis of tinnitus. RESULTS: Among the 400 patients,61% of them did not show the correlation of tinnitus with hearing loss (52...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29123218/identification-of-a-neurocognitive-mechanism-underpinning-awareness-of-chronic-tinnitus
#9
Krysta J Trevis, Chris Tailby, David B Grayden, Neil M McLachlan, Graeme D Jackson, Sarah J Wilson
Tinnitus (ringing in the ears) is a common auditory sensation that can become a chronic debilitating health condition with pervasive effects on health and wellbeing, substantive economic burden, and no known cure. Here we investigate if impaired functioning of the cognitive control network that directs attentional focus is a mechanism erroneously maintaining the tinnitus sensation. Fifteen people with chronic tinnitus and 15 healthy controls matched for age and gender from the community performed a cognitively demanding task known to activate the cognitive control network in this functional magnetic resonance imaging study...
November 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29114973/internal-jugular-vein-stenosis-induced-intracranial-hypertension-can-be-resolved-by-stenting
#10
Da Zhou, Ran Meng, Xuxiang Zhang, Linlin Guo, Sijie Li, Weijuan Wu, Jiangang Duan, Haiqing Song, Yuchuan Ding, Xunming Ji
BACKGROUND: Idiopathic intracranial hypertension (IIH) is characterized by abnormally elevated intracranial pressure (ICP) without identifiable etiology. Recently, however, a subset of patients with presumed IIH have been found with isolated internal jugular vein (IJV) stenosis in the absence of intracranial abnormalities. METHODS: Fifteen consecutive patients were screened from 46 patients suspected as IIH and were finally confirmed as isolated IJV stenosis. The stenotic IJV was corrected with stenting when a trans-stenotic mean pressure gradient (∆MPG) was equal or higher than 5...
November 8, 2017: European Journal of Neurology: the Official Journal of the European Federation of Neurological Societies
https://www.readbyqxmd.com/read/29114160/clinical-characteristics-of-troublesome-pediatric-tinnitus
#11
Annett Szibor, Topi Jutila, Antti Mäkitie, Antti Aarnisalo
Objectives: The frequency of tinnitus in children and adults is practically the same. However, although adults reveal their symptoms and seek for medical aid, the suffering often remains unrecognized in the young. This is due to both the inability of children to properly describe their symptoms and the lack of recognition. Materials and methods: Among 5768 patients entering our department with complaints of tinnitus between 2010 and 2015, there were only 112 children...
2017: Clinical Medicine Insights. Ear, Nose and Throat
https://www.readbyqxmd.com/read/29101995/acr-appropriateness-criteria-%C3%A2-tinnitus
#12
Marcus M Kessler, Marwan Moussa, Julie Bykowski, Claudia F E Kirsch, Joseph M Aulino, Kevin L Berger, Asim F Choudhri, Terry D Fife, Isabelle M Germano, A Tuba Kendi, Jeffrey H Kim, Michael D Luttrull, Diego Nunez, Lubdha M Shah, Aseem Sharma, Vilaas S Shetty, Sophia C Symko, Rebecca S Cornelius
Tinnitus is the perception of sound in the absence of an external source. It is a common symptom that can be related to hearing loss and other benign causes. However, tinnitus may be disabling and can be the only symptom in a patient with a central nervous system process disorder. History and physical examination are crucial first steps to determine the need for imaging. CT and MRI are useful in the setting of pulsatile tinnitus to evaluate for an underlying vascular anomaly or abnormality. If there is concomitant asymmetric hearing loss, neurologic deficit, or head trauma, imaging should be guided by those respective ACR Appropriateness Criteria(®) documents, rather than the presence of tinnitus...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29097035/-good-practices-with-tinnitus-in-adult
#13
Christine Le Pajolec, Martine Ohresser, Jérome Nevoux
The interrogation is essential to trace the genesis of the tinnitus and to appreciate its repercussion. Clinical examination should look for a local, vascular or cervical cause. The ENT consultation with audiogram and tinnitus evaluation is essential to know the characteristics of the tinnitus and to consider the treatment. If tinnitus is accompanied by a decrease in hearing, then wearing hearing aids can correct deafness and decrease the tinnitus. The psychological impact of tinnitus must always be taken into account and the use of a multidisciplinary team is an interesting solution...
October 30, 2017: La Presse Médicale
https://www.readbyqxmd.com/read/29090311/randomized-controlled-trial-of-a-novel-device-for-tinnitus-sound-therapy-during-sleep
#14
Sarah M Theodoroff, Garnett P McMillan, Tara L Zaugg, Megan Cheslock, Chan Roberts, James A Henry
Purpose: The aim of this study was to determine if a customized stimulus from the Otoharmonics Levo System reduces tinnitus perceptions and reactions for people with bothersome tinnitus. Method: Sixty participants were randomized to 1 of 3 groups that used sound therapy devices during sleep that differed in their acoustic stimulus: (a) tinnitus-matched (TM), (b) noise stimulus (NS), and (c) bedside sound generator (BSG). Outcome measures were the Tinnitus Functional Index (TFI), numeric rating scale of tinnitus loudness, and tinnitus loudness match...
October 31, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/29076393/designing-clinical-trials-for-assessing-the-effectiveness-of-interventions-for-tinnitus
#15
Deborah A Hall
In the face of finite resources, allocations of research and health-care funding are dependent upon high-quality evidence. Historically, tinnitus has been the poor cousin of hearing science, with low-quality clinical research providing unreliable estimates of effect and with devices marketed for tinnitus without strong evidence for those product claims. However, the tinnitus field is changing. Key opinion leaders have recently made calls to the field to improve the design, implementation, and reporting of clinical trials, and there is growing intersectoral collaboration...
January 2017: Trends in Hearing
https://www.readbyqxmd.com/read/29074518/bi-modal-stimulation-in-the-treatment-of-tinnitus-a-study-protocol-for-an-exploratory-trial-to-optimise-stimulation-parameters-and-patient-subtyping
#16
Shona D'Arcy, Caroline Hamilton, Stephen Hughes, Deborah A Hall, Sven Vanneste, Berthold Langguth, Brendan Conlon
INTRODUCTION: Tinnitus is the perception of sound in the absence of a corresponding external acoustic stimulus. Bimodal neuromodulation is emerging as a promising treatment for this condition. The main objectives of this study are to investigate the relevance of interstimulus timing and the choices of acoustic and tongue stimuli for a proprietary bimodal (auditory and somatosensory) neuromodulation device, as well as to explore whether specific subtypes of patients are differentially responsive to this novel intervention for reducing the symptoms of chronic tinnitus...
October 25, 2017: BMJ Open
https://www.readbyqxmd.com/read/29071898/-distribution-of-press-sensitive-acupoints-in-patients-with-tinnitus
#17
Mei-Qi Ji, Shan-Shan Tian, Dai Liu, Wei Zhang, Jie-Ping Xie, Ya-Li Zhang, Chun-Hua Li, Yan Gao
OBJECTIVE: To explore the regularity of distribution of press-sensitive acupoints on the body surface in tinnitus patients, so as to provide evidence for selecting suitable acupuncture points in the treatment of tinnitus. METHODS: Sixty-three cases of tinnitus patients (from 25 to 75 years in age) were recruited in the present study. The patient was asked to take a sitting, supine and prone position, successively, and the operator used the thumb to moderately press the subject's head, neck, back, four limbs below the knee- and elbow joints along the three Hand- and three Foot-yang and yin meridians...
December 25, 2016: Zhen Ci Yan Jiu, Acupuncture Research
https://www.readbyqxmd.com/read/29071034/alterations-in-auditory-electrophysiological-responses-associated-with-temporary-suppression-of-tinnitus-induced-by-low-level-laser-therapy-a-before-after-case-series
#18
Katayoon Montazeri, Saeid Mahmoudian, Zahra Razaghi, Mohammad Farhadi
Introduction: Tinnitus is the phantom auditory perception of sound in the absence of an external or internal acoustic stimulus. The treatment is difficult due to multiple etiologies and great psychological influence. The purpose of this study was to determine alterations in auditory physiological and electrophysiological responses associated with temporary suppression of tinnitus induced by low-level laser (LLL) irradiation. Methods: This study was conducted on 20 subjects with subjective tinnitus. All subjects signed the informed consent form and satisfied all the study eligibility criteria...
2017: Journal of Lasers in Medical Sciences
https://www.readbyqxmd.com/read/29064602/brain-stimulation-induced-neuroplasticity-underlying-therapeutic-response-in-phantom-sounds
#19
Timm B Poeppl, Berthold Langguth, Astrid Lehner, Thomas Frodl, Rainer Rupprecht, Peter M Kreuzer, Michael Landgrebe, Martin Schecklmann
Noninvasive brain stimulation can modify phantom sounds for longer periods by modulating neural activity and putatively inducing regional neuroplastic changes. However, treatment response is limited and there are no good demographic or clinical predictors for treatment outcome. We used state-of-the-art voxel-based morphometry (VBM) to investigate whether transcranial magnetic stimulation-induced neuroplasticity determines therapeutic outcome. Sixty subjects chronically experiencing phantom sounds (i.e., tinnitus) received repetitive transcranial magnetic stimulation (rTMS) of left dorsolateral prefrontal and temporal cortex according to a protocol that has been shown to yield a significantly higher number of treatment responders than sham stimulation and previous stimulation protocols...
October 24, 2017: Human Brain Mapping
https://www.readbyqxmd.com/read/29054783/subfrontal-schwannoma-case-report-and-review-of-literature
#20
Vladimir Figueroa-Ángel, Carlos Alberto Rodríguez-Aceves, Willem G Calderon-Miranda, Nidia Escobar-Hernandez, Andrei F Joaquim, Neurosurgeon Luis R Moscote
We present the case of a 46 year old female that presented with right tinnitus, dizziness and bifrontal headache, progressive, starting two years before. Imaging studies reveals an incidentally neoplastic extraaxial homogeneous appearance tumor on the right anterior skull base. She undewernt surgical treatment with total resection of the tumor by a bicoronal approach. The histopathological study reported schwannoma. Although attributte the origin of schwannomas from the the olfactory nerve is near impossible, once they do not have Schwann cells, intracranial supratentorial schwannomas are mainly located in the anterior skull base...
October 17, 2017: World Neurosurgery
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