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Tinnitus treatment

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https://www.readbyqxmd.com/read/28635507/cochlear-implant-effectiveness-in-postlingual-single-sided-deaf-individuals-what-s-the-point
#1
Mareike Finke, Hanna Bönitz, Björn Lyxell, Angelika Illg
OBJECTIVES: By extending the indication criteria for cochlear implants (CI), the population of CI candidates increased in age, as well as range and type of hearing loss. This qualitative study identified factors that contributed to seek CI treatment in single-sided deaf individuals and gained insights how single-sided deafness (SSD) and hearing with a CI affect their lives. DESIGN: An open-ended questionnaire and a standardised inventory (IOI-HA) were used. Qualitative data reflecting the reasons to seek CI treatment and the individual experiences after CI switch-on were collected...
March 5, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28633708/once-daily-dosing-of-amikacin-for-treatment-of-mycobacterium-abscessus-lung-disease
#2
H Lee, Y M Sohn, J Y Ko, S-Y Lee, B W Jhun, H Y Park, K Jeon, D H Kim, S-Y Kim, J E Choi, I J Moon, S J Shin, H J Park, W-J Koh
SETTING: Tertiary referral centre, Samsung Medical Center, South Korea. OBJECTIVE: To evaluate the pharmacokinetic parameters and toxicities of once-daily amikacin (AMK) dosing for lung disease due to Mycobacterium abscessus. DESIGN: A retrospective review of 48 patients with M. abscessus lung disease who received once-daily AMK for 4 weeks between January 2012 and June 2015. RESULTS: With a starting dose of 15 mg/kg/day and adjustment of AMK dose according to the peak serum level (Cmax), the Cmax target of 55-65 μg/ml was achieved in 31...
July 1, 2017: International Journal of Tuberculosis and Lung Disease
https://www.readbyqxmd.com/read/28629874/neural-activity-during-attentional-conflict-predicts-reduction-in-tinnitus-perception-following-rtms
#3
G A James, J D Thostenson, G Brown, G Carter, H Hayes, S P Tripathi, D J Dobry, R B Govindan, J L Dornhoffer, D K Williams, C D Kilts, M S Mennemeier
BACKGROUND: Subjective idiopathic tinnitus is an intrusive, distracting, and potentially disabling disorder characterized by phantom perception of sounds. Although tinnitus has no approved pharmacologic treatment, recent evidence supports the use of repetitive transcranial magnetic stimulation (rTMS) to alleviate tinnitus symptoms. OBJECTIVE/HYPOTHESIS: Repetitive TMS delivered over the middle superior temporal gyrus (STG) may alter ratings of tinnitus awareness and annoyance more than loudness due to change in attentional processing...
June 2, 2017: Brain Stimulation
https://www.readbyqxmd.com/read/28625091/factors-related-to-tinnitus-and-hyperacusis-handicap-in-older-people
#4
Hashir Aazh, Karen Lammaing, Brian C J Moore
OBJECTIVE: The aim was to assess factors related to tinnitus and hyperacusis handicap in older people. DESIGN: Retrospective cross-sectional. STUDY SAMPLE: Data were gathered for 184 patients with an average age of 69 years. RESULTS: Tinnitus handicap as measured via the Tinnitus Handicap Inventory (THI) was significantly predicted by tinnitus annoyance as measured via the visual analogue scale (VAS) (regression coefficient, b = 2...
June 18, 2017: International Journal of Audiology
https://www.readbyqxmd.com/read/28620492/tinnitus-after-administration-of-sublingual-immunotherapy
#5
Jacob Juel
BACKGROUND/OBJECTIVES: Sublingual immunotherapy was first described in 1986. Since then, its use has been increased as an alternative to subcutaneously administered immunotherapy in the treatment of allergic rhinitis. The most common side effects are of oropharyngeal and gastrointestinal in nature, for example, itching, swelling, irritation, ulceration of the oropharynx and nausea, abdominal pain, diarrhoea, and vomiting. More severe side effects are dominated by systemic and respiratory tract manifestations...
2017: SAGE open medical case reports
https://www.readbyqxmd.com/read/28614844/the-effectiveness-of-the-progression-of-widex-zen-tinnitus-therapy-a-pilot-study
#6
Richard S Tyler, Aniruddha K Deshpande, Chi C Lau, Francis Kuk
Purpose: The aim of this study was to measure the progression of benefits to individuals with tinnitus from providing informational counseling, hearing aids, a brief tinnitus activities treatment and Zen therapy. Method: Several magnitude estimation scales and tinnitus handicap scales were administered for the duration of the study to 20 participants. Results: Results indicated that all participants benefited from this sequential approach of providing different components of this tinnitus treatment...
June 15, 2017: American Journal of Audiology
https://www.readbyqxmd.com/read/28608739/safety-of-repeated-dose-intratympanic-injections-with-am-101-in-acute-inner-ear-tinnitus
#7
Hinrich Staecker, Michael Morelock, Timothy Kramer, Pavel Chrbolka, Joong Ho Ahn, Thomas Meyer
Objective To evaluate the safety and tolerability of repeated intratympanic administration of the gel-formulated NMDA receptor antagonist AM-101 in acute patients with inner ear tinnitus. Study Design Prospective, double-blind, randomized, placebo-controlled study. Setting Sixty-nine secondary and tertiary sites in North America, Europe, and Asia. Subjects and Methods In total, 343 subjects with persistent acute tinnitus after traumatic cochlear injury or otitis media were randomized to receive 3 intratympanic doses of either AM-101 0...
June 1, 2017: Otolaryngology—Head and Neck Surgery
https://www.readbyqxmd.com/read/28608387/hydroxyapatite-cement-resurfacing-the-dehiscent-jugular-bulb-novel-treatment-for-pulsatile-tinnitus
#8
Austin N DeHart, Wayne T Shaia, Daniel H Coelho
OBJECTIVES/HYPOTHESIS: The objectives were to discuss the presentation and symptomatology of patients with jugular bulb abnormalities, summarize the literature describing jugular bulb abnormalities, compare methods of treating symptomatic dehiscent jugular bulb, describe a novel surgical technique and pitfalls to repair dehiscent bulbs with hydroxyapatite cement, and present a case series to demonstrate outcomes with this technique STUDY DESIGN: Case series presentation, PubMed literature review, and description of operative technique...
June 13, 2017: Laryngoscope
https://www.readbyqxmd.com/read/28607789/unilateral-enlarged-vestibular-aqueduct-syndrome-and-bilateral-endolymphatic-hydrops
#9
Massimo Ralli, Giuseppe Nola, Luca Sparvoli, Giovanni Ralli
Enlarged vestibular aqueduct (EVA) syndrome is a common congenital inner ear malformation characterized by a vestibular aqueduct with a diameter larger than 1.5 mm, mixed or sensorineural hearing loss that ranges from mild to profound, and vestibular disorders that may be present with a range from mild imbalance to episodic objective vertigo. In our study, we present the case of a patient with unilateral enlarged vestibular aqueduct and bilateral endolymphatic hydrops (EH). EH was confirmed through anamnestic history and audiological exams; EVA was diagnosed using high-resolution CT scans and MRI images...
2017: Case Reports in Otolaryngology
https://www.readbyqxmd.com/read/28590898/tinnitus-management-randomized-controlled-trial-comparing-extended-wear-hearing-aids-conventional-hearing-aids-and-combination-instruments
#10
James A Henry, Garnett McMillan, Serena Dann, Keri Bennett, Susan Griest, Sarah Theodoroff, Shien Pei Silverman, Susan Whichard, Gabrielle Saunders
BACKGROUND: Whereas hearing aids have long been considered effective for providing relief from tinnitus, controlled clinical studies evaluating this premise have been very limited. PURPOSE: The purpose of this study was to systematically determine the relative efficacy of conventional receiver-in-the-canal hearing aids (HA), the same hearing aids with a sound generator (HA+SG), and extended-wear, deep fit hearing aids (EWHA), to provide relief from tinnitus through a randomized controlled trial...
June 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28589104/intratympanic-injection-of-dexamethasone-and-electrocochleographic-data-in-cases-of-definite-one-sided-refractory-meniere-s-disease
#11
Sasan Dabiri Satri, Reza Gharibi, Farzaneh Nejadian, Nasrin Yazdani, Reza Hoseinabadi, Nima Rezazadeh, Mohammad Reza Firouzifar, Saeed Babaei
INTRODUCTION: Meniere's disease (MD) is a disease of the inner ear that presents itself with repeated episodes of vertigo (96.2%), tinnitus (91.1%), and sensorineural hearing loss (87.7 %). In this article we sought to assess the effects of intratympanic (IT) injections of dexamethasone on definite cases of MD using electrocochleography (ECOG). MATERIALS AND METHODS: In this hospital-based case series in 36 patients, we measured audiometric values and ECOG in all patients before, 1 month and 6 months after 4-mg/mL IT injections of dexamethasone...
May 2017: Iranian Journal of Otorhinolaryngology
https://www.readbyqxmd.com/read/28580832/syphilis-gastritis-a-case-report
#12
Kuan Lai, Nicolas Pinto-Sander, Daniel Richardson, Shanshan Wei, Kang Zeng
Awareness of the spectrum of clinical manifestations of syphilis, especially uncommon changes, is essential for diagnosis and effective management of patients. A 48-year-old Han businessman presented to the ear, nose and throat surgeons with an eight-week history of epigastric pain, a four-week history of a widespread non-itchy rash including the scrotal skin and a one-week history of tinnitus and dizziness. On examination, he was afebrile with widespread lymphadenopathy and a maculopapular rash affecting his trunk and scrotum...
January 1, 2017: International Journal of STD & AIDS
https://www.readbyqxmd.com/read/28579955/10-hz-amplitude-modulated-sounds-induce-short-term-tinnitus-suppression
#13
Patrick Neff, Jakob Michels, Martin Meyer, Martin Schecklmann, Berthold Langguth, Winfried Schlee
Objectives: Acoustic stimulation or sound therapy is proposed as a main treatment option for chronic subjective tinnitus. To further probe the field of acoustic stimulations for tinnitus therapy, this exploratory study compared 10 Hz amplitude modulated (AM) sounds (two pure tones, noise, music, and frequency modulated (FM) sounds) and unmodulated sounds (pure tone, noise) regarding their temporary suppression of tinnitus loudness. First, it was hypothesized that modulated sounds elicit larger temporary loudness suppression (residual inhibition) than unmodulated sounds...
2017: Frontiers in Aging Neuroscience
https://www.readbyqxmd.com/read/28558452/-preliminary-analysis-of-the-effects-of-tailor-made-notched-music-therapy-on-chronic-idiopathic-tinnitus
#14
R R Tian, M F Diao, F J Tian, J J Sun, X Lin
Objective: Tailor-made notched music was applied to alleviate the symptoms of chronic idiopathic tinnitus and compared its effectiveness with other existing sound treatment of tinnitus. Methods: Subjects (n=43; ears=75 )were recruited during June 2015 to October 2016 from the out-patients of our hospital. These patients had chronic (longer than 6months) and idiopathic tinnitus, with or without significant sensorineural hearing loss. In the prospective design, the patients were randomly divided into group A (treated with tailor-made notched music) and group B (treated with analogous sound masking), and received the treatment for 3 months...
May 7, 2017: Zhonghua Er Bi Yan Hou Tou Jing Wai Ke za Zhi, Chinese Journal of Otorhinolaryngology Head and Neck Surgery
https://www.readbyqxmd.com/read/28535812/current-insights-in-noise-induced-hearing-loss-a-literature-review-of-the-underlying-mechanism-pathophysiology-asymmetry-and-management-options
#15
REVIEW
Trung N Le, Louise V Straatman, Jane Lea, Brian Westerberg
BACKGROUND: Noise-induced hearing loss is one of the most common forms of sensorineural hearing loss, is a major health problem, is largely preventable and is probably more widespread than revealed by conventional pure tone threshold testing. Noise-induced damage to the cochlea is traditionally considered to be associated with symmetrical mild to moderate hearing loss with associated tinnitus; however, there is a significant number of patients with asymmetrical thresholds and, depending on the exposure, severe to profound hearing loss as well...
May 23, 2017: Journal of Otolaryngology—Head & Neck Surgery
https://www.readbyqxmd.com/read/28535268/evaluation-of-the-glucocorticoid-receptor-as-a-biomarker-of-treatment-response-in-vogt-koyanagi-harada-disease
#16
Cristhian A Urzua, Julia Guerrero, Hector Gatica, Victor Velasquez, Annelise Goecke
Purpose: This study is aimed to investigate the role of glucocorticoid receptor (GR) isoforms in peripheral blood mononuclear cells (PBMC) as biomarkers of glucocorticoid (GC) resistance and to validate a set of clinical predictive factors in patients with Vogt-Koyanagi-Harada (VKH) disease. Methods: This was a prospective cohort study that included a total of 21 patients with VKH. A complete ophthalmologic evaluation was carried out at baseline that recorded the presence of any clinical predictive factors (visual acuity ≤ 20/200, tinnitus, chronic disease, and fundus depigmentation)...
February 1, 2017: Investigative Ophthalmology & Visual Science
https://www.readbyqxmd.com/read/28534733/acute-acoustic-trauma-among-soldiers-during-an-intense-combat
#17
Noam Yehudai, Nir Fink, Manor Shpriz, Tal Marom
BACKGROUND: During military actions, soldiers are constantly exposed to various forms of potentially harmful noises. Acute acoustic trauma (AAT) results from an impact, unexpected intense noise ≥140 dB, which generates a high-energy sound wave that can damage the auditory system. PURPOSE: We sought to characterize AAT injuries among military personnel during operation "Protective Edge," to analyze the effectiveness of hearing protection devices (HPDs), and to evaluate the benefit of steroid treatment in early-diagnosed AAT injury...
May 2017: Journal of the American Academy of Audiology
https://www.readbyqxmd.com/read/28533738/genetics-of-tinnitus-still-in-its-infancy
#18
REVIEW
Barbara Vona, Indrajit Nanda, Wafaa Shehata-Dieler, Thomas Haaf
Tinnitus is the perception of a phantom sound that affects between 10 and 15% of the general population. Despite this considerable prevalence, treatments for tinnitus are presently lacking. Tinnitus exhibits a diverse array of recognized risk factors and extreme clinical heterogeneity. Furthermore, it can involve an unknown number of auditory and non-auditory networks and molecular pathways. This complex combination has hampered advancements in the field. The identification of specific genetic factors has been at the forefront of several research investigations in the past decade...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28529479/in-patients-undergoing-cochlear-implantation-psychological-burden-affects-tinnitus-and-the-overall-outcome-of-auditory-rehabilitation
#19
Petra Brüggemann, Agnieszka J Szczepek, Katharina Klee, Stefan Gräbel, Birgit Mazurek, Heidi Olze
Cochlear implantation (CI) is increasingly being used in the auditory rehabilitation of deaf patients. Here, we investigated whether the auditory rehabilitation can be influenced by the psychological burden caused by mental conditions. Our sample included 47 patients who underwent implantation. All patients were monitored before and 6 months after CI. Auditory performance was assessed using the Oldenburg Inventory (OI) and Freiburg monosyllable (FB MS) speech discrimination test. The health-related quality of life was measured with Nijmegen Cochlear implantation Questionnaire (NCIQ) whereas tinnitus-related distress was measured with the German version of Tinnitus Questionnaire (TQ)...
2017: Frontiers in Human Neuroscience
https://www.readbyqxmd.com/read/28515957/a-psychologically-informed-audiologist-delivered-manualised-intervention-for-tinnitus-protocol-for-a-randomised-controlled-feasibility-trial-tin-man-study
#20
John A Taylor, Deborah A Hall, Dawn-Marie Walker, Mary McMurran, Amanda Casey, David Stockdale, Debbie Featherstone, Dean M Thompson, Carol MacDonald, Derek J Hoare
BACKGROUND: Chronic tinnitus is a common incurable condition often associated with depression, anxiety, insomnia and reduced quality of life. Within National Health Service (NHS) audiology in the United Kingdom (UK), no standard protocol currently exists for the treatment of tinnitus. Counselling is only available in less than half of audiology departments, and there is no agreed standard for what constitutes tinnitus counselling. There is substantial evidence from systematic reviews for the clinical benefit of cognitive behaviour therapy (CBT) for tinnitus delivered by clinical psychologists or psychiatrists, but no studies have sufficiently evidenced the NHS model of tinnitus care where management is increasingly being delivered by audiology professionals...
2017: Pilot and Feasibility Studies
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