keyword
https://read.qxmd.com/read/38638734/overcoming-infertility-challenges-a-case-report-on-the-management-of-ovarian-endometriomas-and-successful-pregnancy-with-intracytoplasmic-sperm-injection-and-platelet-rich-plasma-perfusion
#1
Priyal Tilak, Pranita A Bawaskar, Ankit Badge, Nancy Nair, Avanti Kalbande, Pranjali P Muley
Endometriosis and infertility are clinically associated. The therapeutic approaches for endometriosis, whether medical or surgical, yield distinct outcomes for a woman's potential for achieving conception, whether through natural means or with the aid of assisted reproductive technology (ART). In this case report, a 29-year-old female and her 32-year-old partner, married for the last five years, sought assistance at our fertility clinic after having one failed in vitro fertilization (IVF) cycle. The patient had a history of dysmenorrhea and deep dyspareunia, suggesting the presence of an ovarian cyst...
March 2024: Curēus
https://read.qxmd.com/read/38626453/pathophysiology-and-clinical-implications-of-ovarian-endometriomas
#2
JOURNAL ARTICLE
Farr R Nezhat, Ann M Cathcart, Ceana H Nezhat, Camran R Nezhat
Ovarian endometriomas affect many patients with endometriosis and have significant effects on quality of life, fertility, and risk of malignancy. Endometriomas range from small (1-3 cm), densely fibrotic cysts to large (20 cm or greater) cysts with varying degrees of fibrosis. Endometriomas are hypothesized to form from endometriotic invasion or metaplasia of functional cysts or alternatively from ovarian surface endometriosis that bleeds into the ovarian cortex. Different mechanisms of endometrioma formation may help explain the phenotypic variability observed among endometriomas...
April 16, 2024: Obstetrics and Gynecology
https://read.qxmd.com/read/38621405/safety-of-a-controlled-human-infection-model-of-tuberculosis-with-aerosolised-live-attenuated-mycobacterium-bovis-bcg-versus-intradermal-bcg-in-bcg-naive-adults-in-the-uk-a-dose-escalation-randomised-controlled-phase-1-trial
#3
JOURNAL ARTICLE
Iman Satti, Julia L Marshall, Stephanie A Harris, Rachel Wittenberg, Rachel Tanner, Raquel Lopez Ramon, Morven Wilkie, Fernando Ramos Lopez, Michael Riste, Daniel Wright, Marco Polo Peralta Alvarez, Nicola Williams, Hazel Morrison, Elena Stylianou, Pedro Folegatti, Daniel Jenkin, Samantha Vermaak, Linnea Rask, Ingrid Cabrera Puig, Rebecca Powell Doherty, Alison Lawrie, Paul Moss, Timothy Hinks, Henry Bettinson, Helen McShane
BACKGROUND: Mycobacterium tuberculosis is the main causative agent of tuberculosis. BCG, the only licensed vaccine, provides inadequate protection against pulmonary tuberculosis. Controlled human infection models are useful tools for vaccine development. We aimed to determine a safe dose of aerosol-inhaled live-attenuated Mycobacterium bovis BCG as a surrogate for M tuberculosis infection, then compare the safety and tolerability of infection models established using aerosol-inhaled and intradermally administered BCG...
April 12, 2024: Lancet Infectious Diseases
https://read.qxmd.com/read/38608053/a-giant-ovarian-cyst-torsion-case-report
#4
JOURNAL ARTICLE
He Hongju
INTRODUCTION: Adnexal torsion (AT) is one of a gynecological condition characterized by an acute abdomen. Clinically, a giant ovarian cyst torsion with a diameter of 30 cm is rare. Therefore, an accurate and timely diagnosis and treatment are important. PATIENT CONCERNS: A 25-year-old unmarried female, presented to the emergency department with intermittent abdominal cramps after a sudden change in position. Considering her symptoms and examination, ultrasound, and magnetic resonance imaging (MRI) results, ovarian cyst torsion was suspected...
April 12, 2024: Medicine (Baltimore)
https://read.qxmd.com/read/38607329/reproductive-outcome-after-laparoscopic-ovarian-cystectomy-using-barbed-sutures-versus-conventional-smooth-sutures-a%C3%A2-retrospective-cohort-study
#5
JOURNAL ARTICLE
Jing Ouyang, Huan Dong, Chenxuan Wei, Ruoer Yu, Siqin Yang, Hong Xu
OBJECTIVE: To investigate the effects of barbed and conventional sutures on reproductive outcomes and ovarian reserve after laparoscopic treatment for benign non-endometrioma ovarian cysts. METHODS: This retrospective study was conducted at an affiliated women's hospital between May 2017 and December 2019. Patients with benign non-endometriotic ovarian cysts undergoing laparoscopic cystectomy were included. RESULTS: Patients received barbed sutures (221 patients) or conventional smooth sutures (203 patients) intraoperatively...
April 12, 2024: International Journal of Gynaecology and Obstetrics
https://read.qxmd.com/read/38600914/xanthogranulomatous-oophoritis-mimicking-a-dermoid-cyst-with-ovarian-torsion-a-case-report-and-review-of-the-literature
#6
Carrie A Sibbald, Laura G Cooney, Ross J Molot, Daniel L Pellicer
Xanthogranulomatous oophoritis (XO) is a rare pseudotumor representing a destructive chronic inflammatory process often mistaken for malignancy or tubo-ovarian abscess. Xanthogranulomatous inflammation is most commonly seen in the kidneys and gallbladder and very rarely affects the genitourinary system. Definitive treatment is with surgical removal of affected tissue. This report presents the case of a 42-year-old woman with an 8 cm complex right adnexal cyst concerning for a dermoid cyst presenting with intermittent torsion...
June 2024: Case Reports in Women's Health
https://read.qxmd.com/read/38589122/-tb-mindedness-the-only-way-to-beat-the-great-mimicker-a-case-series-with-atypical-presentation-of-female-genital-tuberculosis
#7
JOURNAL ARTICLE
Ashmita Saha, Nilanchali Singh, Deepika Kashyap, Anshul Kulshrestha, Avir Sarkar, Jai B Sharma, Kallol Kumar Roy
BACKGROUND: Incidence of Tuberculosis (TB) cases in India reported in 2019 is 193 per 1 lakh population [National Tuberculosis Elimination Plan (NTEP)]. In India, annual extra pulmonary TB burden is 20-25%, of which 4% of cases are of urogenital origin (Revised National TB Control Programme, 2019; World Health Organization, 2019). The Ministry of Health and Family Welfare has made a target of eliminating tuberculosis by 2025 under the NTEP by the process of identification, notification and treatment of cases...
April 2024: Indian Journal of Tuberculosis
https://read.qxmd.com/read/38581882/-from-the-tip-to-the-deep-of-the-iceberg-parametrial-involvement-in-endometriosis
#8
REVIEW
Fabio Barra, Simone Ferrero, Carlotta Zorzi, Giulio Evangelisti, Umberto Perrone, Irene Valente, Tommaso Capezzuoli, Gianmarco D'Ancona, Stefano Bogliolo, Giovanni Roviglione, Marcello Ceccaroni
Deep endometriosis (DE) can be localized in the parametrium, a complex bilateral anatomical structure, sometimes necessitating intricate surgical intervention due to the potential involvement of autonomic nerves, uterine artery, and ureter. If endometriotic ovarian cysts have been considered metaphorically representative of "the tip of the iceberg" concerning concealed DE lesions, it is reasonable to assert that parametrial lesions should be construed as the most profound region of this iceberg. Also, based on a subdual clinical presentation, a comprehensive diagnostic parametrial evaluation becomes imperative to strategize optimal management for patients with suspected DE...
April 2, 2024: Best Practice & Research. Clinical Obstetrics & Gynaecology
https://read.qxmd.com/read/38577069/mucinous-neoplasm-of-the-appendix-a-case-report-and-review-of-literature
#9
Hao-Cheng Chang, Jung-Cheng Kang, Ta-Wei Pu, Ruei-Yu Su, Chao-Yang Chen, Je-Ming Hu
BACKGROUND: Appendiceal mucinous neoplasms (AMNs), although not classified as rare, are relatively uncommon tumors most often discovered incidentally during colorectal surgery. Accurate identification of AMNs is difficult due to non-specific symptoms, overlapping tumor markers with other conditions, and the potential for misdiagnosis. This underscores the urgent need for precision in diagnosis to prevent severe complications. CASE SUMMARY: This case report describes the unexpected discovery and treatment of a low-grade AMN (LAMN) in a 74-year-old man undergoing laparoscopic hemicolectomy for transverse colon adenocarcinoma (AC)...
March 27, 2024: World Journal of Gastrointestinal Surgery
https://read.qxmd.com/read/38562412/risk-factors-associated-with-changes-in-serum-anti-m%C3%A3-llerian-hormone-levels-before-and-after-laparoscopic-cystectomy-for-endometrioma
#10
JOURNAL ARTICLE
Chenyu Zhang, Xiaoyan Li, Yi Dai, Zhiyue Gu, Yushi Wu, Hailan Yan, Qiutong Li, Jinghua Shi, Jinhua Leng
BACKGROUND: The objective of our study was to investigate the risk factors for a decrease in ovarian reserve in patients with endometriomas after standardized laparoscopic procedures and evaluation to provide corresponding clinical guidance for patients with fertility requirements. METHODS: Anti-Müllerian hormone (AMH) levels and other clinical data from 233 patients with endometriomas and 57 patients with non-endometrioma ovarian cysts admitted to the Peking Union Medical College Hospital between January 2018 and September 2023 were prospectively analysed...
2024: Frontiers in Endocrinology
https://read.qxmd.com/read/38561673/acetate-ameliorates-ovarian-mitochondrial-dysfunction-in-letrozole-induced-polycystic-ovarian-syndrome-rat-model-by-improving-mitofusin-2
#11
JOURNAL ARTICLE
Kehinde S Olaniyi, Stephanie E Areloegbe
Androgen excess and metabolic abnormality largely contribute to the pathogenesis of polycystic ovarian syndrome (PCOS), which primarily precipitates ovarian dysfunction and infertility in reproductive-age women. Impaired mitochondrial function and epigenetic alteration have been linked to the development of PCOS. However, it is unknown whether acetate would exert a therapeutic effect on ovarian mitochondrial dysfunction in PCOS. Herein, the study hypothesized that acetate reverses ovarian mitochondrial dysfunction in experimental PCOS rat model, possibly through modulation of mitofusin-2 (MFn2)...
April 1, 2024: Journal of Physiological Sciences: JPS
https://read.qxmd.com/read/38551784/ethanol-sclerotherapy-in-the-management-of-ovarian-endometrioma-technical-considerations-for-catheter-and-needle-directed-sclerotherapy
#12
JOURNAL ARTICLE
Aynur Azizova, Turkmen Turan Ciftci, Murat Gultekin, Emre Unal, Okan Akhan, Gurkan Bozdag, Devrim Akinci
PURPOSE: To provide technical guidance on applying catheter-directed and needle-directed ethanol sclerotherapy for endometriomas and present the results of these sclerotherapy methods. MATERIALS AND METHODS: From January 2015 to March 2021, the results of the patients with symptomatic ovarian endometriomas who underwent needle-directed or catheter-directed sclerotherapy were evaluated, retrospectively. The decision to apply which sclerotherapy technique was made during the procedure for each patient considering the following factors: cyst size, cyst location, cyst viscosity, and tissue rigidity...
March 29, 2024: Cardiovascular and Interventional Radiology
https://read.qxmd.com/read/38533288/protective-effect-of-baclofen-on-ovarian-cystogenesis-and-morphine-induced-lipid-profile-change-in-female-rats
#13
JOURNAL ARTICLE
Zahra Jamshidi, Manizheh Karami, Mohsen Khalili, Mehrdad Roghani
INTRODUCTION: Morphine induces ovarian cysts that cause obesity and disrupt sex hormone secretion. Baclofen, a gamma-aminobutyric acid receptor agonist, can help regulate sex hormones and reduce harmful blood lipids by protecting against morphine-induced gamma-aminobutyric acid inhibition. We investigated the prophylactic effect of baclofen in rats receiving morphine by comparing with the untreated groups. MATERIALS AND METHODS: Forty eight female Wistar rats were randomly divided into several groups, including control (saline 1 mL/kg, i...
2024: Indian Journal of Endocrinology and Metabolism
https://read.qxmd.com/read/38515195/clinicopathological-features-and-surgical-procedures-of-adnexal-masses-with-abdominal-pain-in-pediatric-and-adolescent-patients
#14
JOURNAL ARTICLE
Qian Liu, Zhiqiang Li, Huimei Zhou, Dongyan Cao, Jiaxin Yang, Keng Shen, Jinghe Lang
PURPOSE: This study investigated the clinicopathological features and surgical procedures of adnexal masses with abdominal pain in pediatric and adolescent patients. Our objective was to better define the clinical presentation of adnexal torsion and to distinguish characteristics of those with torsion and those with an alternate diagnosis. METHODS: Retrospective cohort study of 212 pediatric and adolescent patients was performed who admitted for abdominal pain and presenting with an adnexal mass between March 2012 to December 2019...
March 21, 2024: Orphanet Journal of Rare Diseases
https://read.qxmd.com/read/38500914/characteristics-of-polycystic-ovary-syndrome-a-case-report-investigating-the-role-of-kapha-and-pitta-doshas
#15
Ritesh Jadhav, Akash More, Shirish Vaidya, Namrata Choudhary, Shilpa Dutta, Krushnali S Kadu, Gauri Gajabe
Polycystic ovary syndrome (PCOS) presents complex challenges in diagnosis and treatment due to its multifactorial nature. This case study focuses on a 31-year-old woman exhibiting symptoms of weight gain, irregular menstruation cycles, and hirsutism, leading to a diagnosis of PCOS. Conventional diagnostic criteria and ultrasound confirmation of multiple ovarian cysts supported the diagnosis. By integrating Ayurvedic principles alongside Western medical techniques, this study sought to address imbalances in the Kapha and Pitta doshas, fundamental energies according to Ayurveda, believed to contribute to PCOS symptoms...
February 2024: Curēus
https://read.qxmd.com/read/38485395/-surgical-treatments-for-endometriosis
#16
JOURNAL ARTICLE
Afchine Fazel, Justine Boitard
Complete resection of scattered superficial lesions can be paradoxically more complex. If the endometriosis is ovarian, priority should be given to preserving the oocyte capital, and ovarian function should be assessed in patients of childbearing age who wish to become pregnant, prior to treatment by alcoholization of the cyst, abrasion of its contents by laser or plasma energy, or even cystectomy. Laparoscopic resection is recommended in cases of deep endometriosis. After a thorough clinical examination and precise imaging, deep lesions are treated by resection and shaving in the case of digestive or ureteral localizations, or even by discoid resection or digestive anastomosis resection with or without stoma, depending on fistula risk criteria...
March 2024: Revue de L'infirmière
https://read.qxmd.com/read/38484797/effects-of-melatonin-and-metformin-on-the-ovaries-of-rats-with-polycystic-ovary-syndrome
#17
JOURNAL ARTICLE
Leonardo Augusto Lombardi, Leandro Sabará Mattos, Ana Paula Espindula, Ricardo Santos Simões, Gisela Rodrigues da Silva Sasso, Manuel de Jesus Simões, José Maria Soares-Jr, Rinaldo Florencio-Silva
OBJECTIVE: To study the combined and isolated effects of melatonin and metformin in ovarian tissue of PCOS rats. DESIGN: Forty adult female rats were divided into five groups: physiological estrus phase (Sham); permanent estrus with PCOS induced by continuous lighting exposure for 60 consecutive days (Control); with PCOS treated with melatonin; with PCOS treated with metformin; with PCOS treated with melatonin+metformin. After 60 days of treatments, all rats were euthanized and ovaries were collected and processed for paraffin-embedding...
March 12, 2024: F&S science
https://read.qxmd.com/read/38483428/the-use-of-hormonal-contraceptives-in-fertility-treatments-a-committee-opinion
#18
JOURNAL ARTICLE
(no author information available yet)
The use of hormonal contraception can be considered to aid in the timing of assisted reproductive technology cycles, reduce the risk of ovarian cysts at in vitro fertilization cycle initiation, and optimize visualization before hysteroscopy.
March 13, 2024: Fertility and Sterility
https://read.qxmd.com/read/38472314/epidemiologic-and-genetic-associations-of-female-reproductive-disorders-with-depression-or-dysthymia-a-mendelian-randomization-study
#19
JOURNAL ARTICLE
Shuyi Ling, Yuqing Dai, Ruoxin Weng, Yuan Li, Wenbo Wu, Ziqiong Zhou, Zhisheng Zhong, Yuehui Zheng
Observational studies have previously reported an association between depression and certain female reproductive disorders. However, the causal relationships between depression and different types of female reproductive disorders remain unclear in terms of direction and magnitude. We conducted a comprehensive investigation using a two-sample bi-directional Mendelian randomization analysis, incorporating publicly available GWAS summary statistics. Our aim was to establish a causal relationship between genetically predicted depression and the risk of various female reproductive pathological conditions, such as ovarian dysfunction, polycystic ovary syndrome(PCOS), ovarian cysts, abnormal uterine and vaginal bleeding(AUB), endometriosis, leiomyoma of the uterus, female infertility, spontaneous abortion, eclampsia, pregnancy hypertension, gestational diabetes, excessive vomiting in pregnancy, cervical cancer, and uterine/endometrial cancer...
March 12, 2024: Scientific Reports
https://read.qxmd.com/read/38465761/pediatric-psoriasis-associated-with-van-wyk-grumbach-syndrome-a-case-report
#20
JOURNAL ARTICLE
Asma Marzouk, Rania Mezzi, Saida Zelfani, Nour Jelaila, Saad Ayeb, Asma Bouaziz
INTRODUCTION: Psoriasis is a common chronic inflammatory condition, often beginning in childhood in approximately one-third of cases. It can be associated with various other autoimmune diseases such as rheumatoid arthritis, celiac disease, and thyroid disorders. However, its co-occurrence with Van Wyk Grumbach syndrome has not been described in the pediatric population. This syndrome, resulting from untreated hypothyroidism, is characterized by early puberty and ovarian cysts. OBSERVATION: A 15-year-old adolescent with a diagnosis of psoriasis since the age of 9 presented with chronic constipation and headaches...
October 5, 2023: La Tunisie Médicale
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