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improved vo2

Lieselot Decroix, Cajsa Tonoli, Elodie Lespagnol, Constantino Balestra, Amandine Descat, Marie Jose Drittij-Reijnders, Jamie R Blackwell, Wilhelm Stahl, Andrew M Jones, Antje R Weseler, Aalt Bast, Romain Meeusen, Elsa Heyman
INTRODUCTION: During exercise in hypoxia, O2 delivery to brain and muscle is compromised and oxidative stress is elicited. Cocoa flavanols (CF) have antioxidant capacities and can increase blood flow by stimulating endothelial function. We aimed to examine the effects of 7-day CF intake on oxidative stress, nitric oxide production and tissue oxygenation in response to exercise in hypoxia (14.3% O2 ). METHODS: In a randomized, double blind, cross-over study, 14 well-trained male cyclists completed 4 trials: exercise in normoxia or hypoxia, after 7-day CF or placebo intake...
March 15, 2018: Journal of Applied Physiology
Robert T Mankowski, Victor M Niemeijer, Jasper P Jansen, Lotte Spraakman, Henk J Stam, Stephan F E Praet
Purpose: It is still equivocal whether oxygen uptake recovery kinetics are limited by oxygen delivery and can be improved by supplementary oxygen. The present study aimed to investigate whether measurements of muscle and pulmonary oxygen uptake kinetics can be used to assess oxygen delivery limitations in healthy subjects. Methods: Sixteen healthy young adults performed three sub-maximal exercise tests (6 min at 40% Wmax ) under hypoxic (14%O2 ), normoxic (21%O2 ) and hyperoxic (35%O2 ) conditions on separate days in randomized order...
June 2017: Journal of Exercise Science and Fitness
Daniela G L Terson de Paleville, Susan J Harkema, Claudia A Angeli
CONTEXT: Four individuals with motor complete SCI with an implanted epidural stimulator who were enrolled in another study were assessed for cardiovascular fitness, metabolic function and body composition at four time points before, during, and after task specific training. Following 80 locomotor training sessions, a 16-electrode array was surgically placed on the dura (L1-S1 cord segments) to allow for electrical stimulation. After implantation individuals received 160 sessions of task specific training with epidural stimulation (stand and step)...
March 14, 2018: Journal of Spinal Cord Medicine
Jungyun Hwang, Kiyoung Kim, R Matthew Brothers, Darla M Castelli, F Gonzalez-Lima
Studies of the effects of physical activity on cognition suggest that aerobic fitness can improve cognitive abilities. However, the physiological mechanisms for the cognitive benefit of aerobic fitness are less well understood. We examined the association between aerobic fitness and cerebrovascular function with neurocognitive functions in healthy, young adults. Participants aged 18-29 years underwent measurements of cerebral vasomotor reactivity (CVMR) in response to rebreathing-induced hypercapnia, maximal oxygen uptake (VO2 max) during cycle ergometry to voluntary exhaustion, and simple- and complex-neurocognitive assessments at rest...
March 14, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Pedro B Junior, Vitor L de Andrade, Eduardo Z Campos, Carlos A Kalva-Filho, Alessandro M Zagatto, Gustavo G de Araújo, Marcelo Papoti
Due to the controversy about the sensitive of lactate minimum intensity (LMI) to training and the need to develop other tool for aerobic fitness evaluation, the purpose of this study was to analyze the sensitivity of glucose minimum intensity (GMI) and LMI to endurance training. Eight trained male cyclists (21.4 ± 1.9 years, 67.6 ± 7.5 kg and 1.72 ± 0.10 m) were evaluated twice, before and after 12 weeks of training. GMI and LMI were calculated, respectively, by the lowest blood glucose and lactate values attained during an incremental test performed after a hyperlactemia induction, and VO2 max was determined during standard incremental effort...
March 2018: Journal of Sports Science & Medicine
V G C Ribeiro, V A Mendonça, A L C Souza, S F Fonseca, A C R Camargos, V K S Lage, C D C Neves, J M Santos, L A C Teixeira, E L M Vieira, A L Teixeira Junior, B Mezêncio, J S C Fernandes, H R Leite, J R Poortmans, A C R Lacerda
The aims of this study were 1) to characterize the intensity of the vibration stimulation in women diagnosed with fibromyalgia (FM) compared to a control group of healthy women (HW) matched by age and anthropometric parameters, and 2) to investigate the effect of a single session of whole body vibration (WBV) on inflammatory responses. Levels of adipokines, soluble tumor necrosis factor receptors (sTNFr1, sTNFr2), and brain-derived neurotrophic factor (BDNF) were determined by enzyme-linked immunosorbent assay...
March 1, 2018: Brazilian Journal of Medical and Biological Research, Revista Brasileira de Pesquisas Médicas e Biológicas
James Steele, Andrew Butler, Zoe Comerford, Jason Dyer, Nathan Lloyd, Joshua Ward, James Fisher, Paulo Gentil, Christopher Scott, Hayao Ozaki
The present study examined the effects of exercise utilising traditional resistance training (leg press) or 'cardio' exercise (recumbent cycle ergometry) modalities upon acute physiological responses. Nine healthy males underwent a within session randomised crossover design where they completed both the leg press and recumbent cycle ergometer conditions. Conditions were approximately matched for effort and duration (leg press: 4 × 12RM using a 2 s concentric and 3 s eccentric repetition duration controlled with a metronome, thus each set lasted  60 s; recumbent cycle ergometer: 4 × 60 s bouts using a resistance level permitting 80-100 rpm but culminating with being unable to sustain the minimum cadence for the final 5-10 s)...
2018: PeerJ
Caroline M Van De Heyning, Catherine De Maeyer, Nele Pattyn, Paul J Beckers, Véronique A Cornelissen, Kaatje Goetschalckx, Nadine Possemiers, Emeline M Van Craenenbroeck, Jens-Uwe Voigt, Luc Vanhees, Bharati Shivalkar
BACKGROUND: Increase of exercise capacity (peak VO2 ) after cardiac rehabilitation improves outcome in patients with coronary artery disease (CAD). Systolic and diastolic function have been associated with peak VO2 , but their role towards improvement of exercise capacity remains unclear. It is unknown which exercise intensity has the most beneficial impact on left ventricular (LV) geometry and function in CAD patients without heart failure. METHODS: 200 stable CAD patients without heart failure were randomized to 3months of aerobic interval training (AIT) or aerobic continuous training (ACT)...
April 15, 2018: International Journal of Cardiology
Ceren Yarar-Fisher, Keith Fl Polston, Mualla Eraslan, Kathryn Y Henley, Gizem I Kinikli, C Scott Bickel, Samuel T Windham, Amie B McLain, Robert A Oster, Marcas M Bamman
This study compares the effects of an 8-week iso-caloric high protein (HP) diet versus a combination exercise (Comb-Ex) regimen on paralytic vastus lateralis (VL) and non-paralytic deltoid muscle in individuals with long-standing spinal cord injury (SCI). Fiber type distribution, cross-sectional area (CSA), levels of translation initiation signaling proteins (Erk-1/2, Akt, p70S6K1, 4EBP1, RPS6, and FAK), and lean thigh mass were analyzed at baseline and after the 8-week interventions. A total of 11 participants (C5-T12 levels, 21...
March 1, 2018: Journal of Applied Physiology
James W Morgan, Eric Ferrazzani, J Andrew Taylor, Isabelle Vivodtzev
High level spinal cord injury (SCI) results in a very limited innervated skeletal muscle mass that strongly reduces exercise capacity. Our recent work showed that when adding functional electrical stimulation (FES) of the paralyzed legs (hybrid FES exercise) to produce higher exercise capacity, peak ventilation became a limiting factor to training-induced improvement in aerobic capacity. Our assumption was that the systemic adaptations to exercise training are delimited by the maximal ventilation that can be achieved...
March 1, 2018: Journal of Applied Physiology
Jaime Gallo-Villegas, Juan Carlos Aristizabal, Mauricio Estrada, Luis H Valbuena, Raul Narvaez-Sanchez, Jorge Osorio, Daniel C Aguirre-Acevedo, Juan C Calderón
BACKGROUND: Evidence of the efficacy of high-intensity, low-volume interval training (HIIT-low volume) in treating insulin resistance (IR) in patients with metabolic disorders is contradictory. In addition, it is unknown whether this effect is mediated through muscle endocrine function, which in turn depends on muscle mass and fiber type composition. Our aims were to assess the efficacy of HIIT-low volume compared to continuous aerobic exercise (CAE) in treating IR in adults with metabolic syndrome (MS) and to establish whether musclin, apelin, muscle mass and muscle composition are mediators of the effect...
February 27, 2018: Trials
Mansueto Gomes Neto, Filipe Ferrari Ribeiro de Lacerda, Antonio Alberto Lopes, Bruno Prata Martinez, Micheli Bernardone Saquetto
OBJECTIVE: To determine the effects of different intradialytic exercise training modalities on physical functioning and health-related quality of life of maintenance hemodialysis patients. METHODS: We searched MEDLINE, Cochrane Trials Register and CINAHL for controlled trials that evaluated the effects of intradialytic exercise training for maintenance hemodialysis patients and published from the earliest available date to December 2017. Weighted mean difference and 95% confidence interval (CI) were calculated, and heterogeneity was assessed using the I2 test...
February 1, 2018: Clinical Rehabilitation
Hassan Khan, Setor K Kunutsor, Rainer Rauramaa, Faisal M Merchant, Jari A Laukkanen
The benefits of aerobic fitness in relation to all-cause and cardiovascular mortality is well established; however, the associations of long-term change in cardiorespiratory fitness (CRF) with incident heart failure (HF) and atrial fibrillation (AF) have not been studied before. The Kuopio Ischaemic Heart Disease Risk Factor Study is a prospective cohort comprising men aged 42 to 60 years from the city of Kuopio and its surroundings, with a baseline examination between 1984 and 1989 (V1), a re-examination at 11 years (V2), and up to 15 years of follow-up from V2...
February 2, 2018: American Journal of Cardiology
Paul Robach, Joar Hansen, Aurélien Pichon, Anne-Kristine Meinild Lundby, Sune Dandanell, Gunnar Slettaløkken Falch, Daniel Hammarström, Dominik H Pesta, Christoph Siebenmann, Stefanie Keiser, Patricia Kérivel, Jon Elling Whist, Bent R Rønnestad, Carsten Lundby
Live high - train low (LHTL) using hypobaric hypoxia was previously found to improve sea-level endurance performance in well-trained individuals, however confirmatory controlled data in athletes are lacking. Here we test the hypothesis that natural-altitude LHTL improves aerobic performance in cross-country skiers, in conjunction with expansion of total hemoglobin mass (Hbmass , carbon-monoxide rebreathing technique) promoted by accelerated erythropoiesis. Following duplicate baseline measurements at sea level over the course of two weeks, nineteen Norwegian cross-country skiers (three women, sixteen men, age 20±2 yr, maximal oxygen uptake (VO2 max) 69±5 ml...
February 22, 2018: Scandinavian Journal of Medicine & Science in Sports
O V Kamenskaya, I Y Loginova, D V Doronin, A M CHernyavskiy
Aim of the study was assessment of efficiency of lung ventilation and its relationship with quality of life in patients undergoing orthotopic heart transplantation (OHT). MATERIALS AND METHODS: The study involved 40 patients with terminal chronic heart failure (CHF) included in the waiting list for heart transplantation. Before surgery and after OHT all patients underwent cardiopulmonary exercise testing, evaluation of clinical status and quality of life (QL) according to the 36-Item Short Form Survey (SF-36)...
January 2018: Kardiologiia
Shahin Ahmedov, Baris Filiz
OBJECTIVES: An enhancement of aerobic capacity has always been in the scope of various exercise programs. Apart from traditional, like endurance training, methods to improve aerobic performance, there is growing interest to alternative bodywork techniques, like massage, yoga, and acupuncture. This study aimed to investigate the acupressure effect on maximal aerobic capacity (VO2 max) in healthy young adult males. DESIGN: Forty young healthy participants were randomly divided into intervention (n = 20) and control (n = 20) groups...
February 20, 2018: Journal of Alternative and Complementary Medicine: Research on Paradigm, Practice, and Policy
Jessica Whibley, Christopher J Peters, Laura J Halliday, Asif M Chaudry, William H Allum
INTRODUCTION: Esophageal and gastric cancer have a poor prognosis and surgical intervention is associated with considerable morbidity, highlighting the need for careful preoperative assessment. The Incremental Shuttle Walk Test (ISWT) and Cardiopulmonary exercise testing (CPET) can assess preoperative fitness. This study aims to investigate their correlation with both postoperative respiratory complications and overall survival. PATIENTS AND METHODS: Patients were identified who underwent esophageal or gastric resections for cancer between 2010 and 2014 and had ISWT and/or CPET assessments...
February 6, 2018: European Journal of Surgical Oncology
Rebecca L Scalzo, Timothy A Bauer, Kylie Harrall, Kerrie Moreau, Cemal Ozemek, Leah Herlache, Shawna McMillin, Amy G Huebschmann, Jennifer Dorosz, Jane E B Reusch, Judith G Regensteiner
Background: People with type 2 diabetes (T2D) have impaired exercise capacity, even in the absence of complications, which is predictive of their increased cardiovascular mortality. Cardiovascular dysfunction is one potential cause of this exercise defect. Acute infusion of vitamin C has been separately shown to improve diastolic and endothelial function in prior studies. We hypothesized that acute vitamin C infusion would improve exercise capacity and that these improvements would be associated with improved cardiovascular function...
2018: Diabetology & Metabolic Syndrome
Thomas Schmidt, Birna Bjarnason-Wehrens, Stephanie Mommertz, Meike Hannig, Sebastian Schulte-Eistrup, Detlev Willemsen, Nils Reiss
Following implantation of a left ventricular assist device (LVAD), acceptable functional performance is now being achieved; however, peak VO 2 and peak work load (watts) remain considerably limited. Maximum physical capacity is essentially dependent on generated cardiac output (CO) and arteriovenous oxygen difference (avDO 2 ). We investigated the changes in CO and avDO 2 during exercise in LVAD patients with an HVAD pump (HeartWare Inc., Framingham, MA, USA). Approximately 6 weeks after implantation, 20 patients (100% male, 60...
February 12, 2018: Artificial Organs
Liam McAuliffe, Gaynor C Parfitt, Roger G Eston, Caitlin Gray, Hannah A D Keage, Ashleigh E Smith
 Background: Exercise adherence in already low-active older adults with and without mild cognitive impairment (MCI) remains low. Perceptual regulation and exergaming may facilitate future exercise behaviour by improving the affective experience, however evidence that this population can perceptually regulate is lacking. To explore this, we investigated 1) perceptual regulation of exercise intensity during either exergaming or regular ergometer cycling and 2) explored affective responses...
2018: BMC Sports Science, Medicine and Rehabilitation
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