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https://www.readbyqxmd.com/read/28913383/the-effect-of-sagittal-femoral-bowing-on-the-femoral-component-position-in-total-knee-arthroplasty
#1
Seyyed Morteza Kazemi, Tooraj Shafaghi, Reza Minaei, Reza Osanloo, Hashem Abrishamkarzadeh, Farshad Safdari
In the current study, we investigated that how sagittal femoral bowing can affect the sagittal alignment of the femoral component in total knee arthroplasty (TKA). There were 25 patients underwent TKA. Long leg radiography in lateral view was performed. The sagittal femoral bowing (SFB) and component alignment in relation to the sagittal mechanical axis and distal anterior cortical line (DACL) were measured. Finally, the correlation of component alignment and SFB was examined. Mean SFB was 7±2.7 degrees. The component was in flexion position in relation to mechanical axis and DACL as 8...
July 2017: Archives of Bone and Joint Surgery
https://www.readbyqxmd.com/read/28904636/the-orthopaedic-management-of-lower-limb-deformity-in-hypophosphataemic-rickets
#2
A Horn, J Wright, D Bockenhauer, W Van't Hoff, D M Eastwood
BACKGROUND: Many patients with X-linked hypophosphataemic rickets (X-LHPR) demonstrate significant lower limb deformity despite optimal medical management. This study evaluates the use of guided growth by means of hemi-epiphysiodesis to address coronal plane deformity in the skeletally immature child. METHODS: Since 2005, 24 patients with X-LHPR have been referred to our orthopaedic unit for evaluation. All patients had standardised long leg radiographs that were analysed sequentially before and after surgery if any was performed...
August 1, 2017: Journal of Children's Orthopaedics
https://www.readbyqxmd.com/read/28891825/hemiepiphyseodesis-for-juvenile-and-adolescent-tibia-vara-utilizing-percutaneous-transphyseal-screws
#3
Robert F Murphy, Mark A Pacult, William R Barfield, James F Mooney
BACKGROUND: In juvenile and adolescent tibia vara patients with sufficient growth remaining, implant-controlled hemiepiphyseodesis, or guided growth, can be used to correct deformity. Recent reports have described hardware failure of certain hemiepiphyseodesis implants in overweight patients with tibia vara. We describe our experience using transphyseal screws to correct deformity in this patient population. METHODS: A retrospective chart and radiograph review was conducted on all juvenile and adolescent tibia vara patients who underwent lateral proximal tibial hemiepiphyseodesis using a single transphyseal screw...
September 7, 2017: Journal of Pediatric Orthopedics
https://www.readbyqxmd.com/read/28888904/changes-in-biomechanical-risk-factors-for-knee-osteoarthritis-and-their-association-with-5-year-clinically-important-improvement-after-limb-realignment-surgery
#4
Trevor B Birmingham, Rebecca Moyer, Kristyn Leitch, Bert Chesworth, Dianne Bryant, Kevin Willits, Robert Litchfield, Peter J Fowler, J Robert Giffin
OBJECTIVE: To evaluate 5-year outcomes after lower limb realignment and test the hypothesis that surgery-induced changes in selected biomechanical risk factors for medial knee OA are associated with clinically important improvements. DESIGN: We prospectively evaluated patient-reported outcomes, full-limb standing radiographs and gait biomechanics before, 6 months (surgery-induced change) and 5 years after medial opening wedge high tibial osteotomy (HTO) in 170 patients (46...
September 6, 2017: Osteoarthritis and Cartilage
https://www.readbyqxmd.com/read/28874974/evaluation-of-sagittal-spine-pelvis-lower-limb-alignment-in-elderly-women-with-pelvic-retroversion-while-standing-and-walking-using-a-three-dimensional-musculoskeletal-model
#5
Ken Sasaki, Michio Hongo, Naohisa Miyakoshi, Toshiki Matsunaga, Shin Yamada, Hiroaki Kijima, Yoichi Shimada
STUDY DESIGN: In vivo biomechanical study using a three-dimensional (3D) musculoskeletal model for elderly individuals with or without pelvic retroversion. PURPOSE: To evaluate the effect of pelvic retroversion on the sagittal alignment of the spine, pelvis, and lower limb in elderly females while standing and walking. OVERVIEW OF LITERATURE: Patients with hip-spine syndrome have concurrent hip-joint and spine diseases. However, the dynamic sagittal alignment between the hip joint and spine has rarely been investigated...
August 2017: Asian Spine Journal
https://www.readbyqxmd.com/read/28854938/the-assessment-of-femoral-shaft-morphology-in-the-sagittal-plane-in-chinese-patients-with-osteoarthritis-a-radiographic-analysis
#6
Zhengyuan Bao, Liang Qiao, Jianghui Qin, Jiacheng Xu, Sheng Zhou, Dongyang Chen, Dongquan Shi, Jin Dai, Yao Yao, Qing Jiang, Zhihong Xu
BACKGROUND: The purpose of this study was to analyze femoral shaft sagittal parameters in Chinese osteoarthritis (OA) patients undergoing total knee arthroplasty (TKA) and identify whether the parameters in the coronal plane could be predictors of those in the sagittal plane. METHODS: Standard long-standing anteroposterior and femoral lateral radiographs of 50 lower limbs in 50 Chinese OA patients were included. Sagittal femoral bowing angle (sFBA), angle between femoral distal anterior cortex axis and sagittal mechanical axis (DACSMA), angle between femoral distal anterior cortex axis and sagittal distal anatomic axis (DACSDAA), and angle between femoral sagittal mechanical axis and sagittal distal anatomic axis (SMADAA) were measured...
August 30, 2017: Journal of Orthopaedic Surgery and Research
https://www.readbyqxmd.com/read/28835990/cerebellar-compartments-for-the-processing-of-kinematic-and-kinetic-information-related-to-hindlimb-stepping
#7
M S Valle, G Bosco, R E Poppele
We previously showed that proprioceptive sensory input from the hindlimbs to the anterior cerebellar cortex of the cat may not be simply organized with respect to a body map, but it may also be distributed to multiple discrete functional areas extending beyond classical body map boundaries. With passive hindlimb stepping movements, cerebellar activity was shown to relate to whole limb kinematics as does the activity of dorsal spinocerebellar tract (DSCT) neurons. For DSCT activity, whole limb kinematics provides a solid functional framework within which information about limb forces, such as those generated during active stepping, may also be embedded...
August 23, 2017: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
https://www.readbyqxmd.com/read/28834131/alterations-in-anterior-posterior-patterning-and-its-accompanying-changes-along-the-proximal-distal-axis-during-the-fin-to-limb-transition
#8
REVIEW
Mikiko Tanaka
The evolution from fins to limbs was one of the most successful innovations for vertebrates, allowing them to vastly expand their behaviors and habitats. Fossil records suggest that morphological changes occurred not only along the proximal-distal axis included appearance of the autopod, but also occurred along the anterior-posterior axis included reductions in the size and number of basal bones and digits. This review focuses on recent progress in developmental and genetic studies aimed at elucidating the mechanisms underlying alteration of anterior-posterior patterning and its accompanying changes along the proximal-distal axis during the fin-to-limb transition...
August 19, 2017: Genesis: the Journal of Genetics and Development
https://www.readbyqxmd.com/read/28827057/ilizarov-hip-reconstruction-osteotomy-a-review
#9
Masood Umer, Talal Aqueel Quadri, Rizwan Haroon Rashid
Hip joint instability can be secondary to congenital hip pathologies like developmental dysplasia (DDH) or acquired such as sequel of infective or neoplastic process. An unstable hip is usually associated with loss of bone from the proximal femur, shortening, abnormal gait, and pain. Many authors have suggested proximal femoral valgus osteotomy for the treatment of unstable hip joints. Ilizarov modified this technique and performed a double-level osteotomy. In addition to proximal femoral valgus extension osteotomy, he introduced a distal femoral varus osteotomy which would lead to limb lengthening and correction of mechanical axis of the leg...
August 18, 2017: International Journal of Surgery
https://www.readbyqxmd.com/read/28813880/series-elastic-actuation-of-an-elbow-rehabilitation-exoskeleton-with-axis-misalignment-adaptation
#10
Kuan-Yi Wu, Yin-Yu Su, Ying-Lung Yu, Kuei-You Lin, Chao-Chieh Lan
Powered exoskeletons can facilitate rehabilitation of patients with upper limb disabilities. Designs using rotary motors usually result in bulky exoskeletons to reduce the problem of moving inertia. This paper presents a new linearly actuated elbow exoskeleton that consists of a slider crank mechanism and a linear motor. The linear motor is placed beside the upper arm and closer to shoulder joint. Thus better inertia properties can be achieved while lightweight and compactness are maintained. A passive joint is introduced to compensate for the exoskeleton-elbow misalignment and intersubject size variation...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28752819/computer-assisted-navigation-in-total-knee-and-hip-arthroplasty
#11
Kamal Deep, Shivakumar Shankar, Ashish Mahendra
INTRODUCTION: Computer assisted surgery was pioneered in early 1990s. The first computer assisted surgery (CAS) total knee replacement with an imageless system was carried out in 1997. In the past 25 years, CAS has progressed from experimental in vitro studies to established in vivo surgical procedures. METHODS: A comprehensive body of evidence establishing the advantages of computer assisted surgery in knee and hip arthroplasty is available. Established benefits have been demonstrated including its role as an excellent research tool...
2017: SICOT-J
https://www.readbyqxmd.com/read/28736125/minimally-invasive-treatment-of-displaced-femoral-shaft-fractures-with-a-teleoperated-robot-assisted-surgical-system
#12
Qing Zhu, Bin Liang, Xingsong Wang, Xiaogang Sun, Liming Wang
BACKGROUND: Minimally invasive surgical operation of intramedullary (IM) nailing is a standard technique for treating diaphyseal fractures. However, in addition to its advantages, there are some drawbacks such as the frequent occurrence of malalignment, physical fatigue and high radiation exposure to medical staff. The use of robotic and navigation techniques is promising treatments for femoral fractures. MATERIALS AND METHODS: This paper presents a novel robot-assisted manipulator for femoral shaft fracture reduction with indirect contact with the femur...
July 12, 2017: Injury
https://www.readbyqxmd.com/read/28721459/measurement-of-lower-limb-alignment-there-are-within-person-differences-between-weight-bearing-and-non-weight-bearing-measurement-modalities
#13
Daphne A L Schoenmakers, Peter Z Feczko, Bert Boonen, Martijn G M Schotanus, Nanne P Kort, Pieter J Emans
PURPOSE: Previous studies have compared weight-bearing mechanical leg axis (MLA) measurements to non-weight-bearing measurement modalities. Most of these studies compared mean or median values and did not analyse within-person differences between measurements. This study evaluates the within-person agreement of MLA measurements between weight-bearing full-length radiographs (FLR) and non-weight-bearing measurement modalities (computer-assisted surgery (CAS) navigation or MRI). MATERIALS AND METHODS: Two independent observers measured the MLA on pre- and postoperative weight-bearing FLR in 168 patients...
July 18, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28701852/encouraging-treatment-algorithm-for-computer-assisted-navigated-total-knee-arthroplasty-tka-a-retrospective-cohort-analysis
#14
J Cip, M Widemschek, C Bach, P Ruckenstuhl, T Benesch, K Studer, A Martin
OBJECTIVE: Navigated computer-assisted total knee arthroplasty (TKA) shows inconclusive mid- to long-term outcome results and is limited by increased costs, surgery-time and an additional learning curve. We introduced a treatment algorithm preserving computer-assisted TKA for patients with adipositas-per-magna, posttraumatic leg-deformities, osteosynthetic material in-situ or reduced preoperative X-ray quality. METHODS: 237 primary unilateral TKA were allocated based on the treatment concept described above...
September 2017: Journal of Orthopaedics
https://www.readbyqxmd.com/read/28697789/improvement-in-asymmetric-dimethylarginine-and-oxidative-stress-in-patients-with-limb-salvage-after-autologous-mononuclear-stem-cell-application-for-critical-limb-ischemia
#15
Juraj Madaric, Martina Valachovicova, Ludovit Paulis, Jana Pribojova, Renata Mateova, Katarina Sebekova, Luba Postulkova, Terezia Madaricova, Maria Bucova, Martin Mistrik, Ivan Vulev
BACKGROUND: Asymmetric dimethylarginine (ADMA), an endogenous inhibitor of nitric oxide synthase, acts as an inhibitor of angiogenesis and is associated with an increased risk of cardiovascular mortality. Administration of stem cells may affect endogenous mechanisms that regulate ADMA production and metabolism. The aim of the present study was to analyze ADMA concentration and changes in oxidative stress in patients with advanced critical limb ischemia (CLI) after bone marrow-derived mononuclear cell (BM-MNC) therapy...
July 12, 2017: Stem Cell Research & Therapy
https://www.readbyqxmd.com/read/28690462/open-wedge-distal-femoral-osteotomy-accuracy-of-correction-and-patient-outcomes
#16
Osama Elattar, Ishaan Swarup, Aaron Lam, Joseph Nguyen, Austin Fragomen, S Robert Rozbruch
BACKGROUND: There is a renewed interest in joint preservation surgery, and lateral opening wedge distal femoral osteotomy (DFO), a joint-preserving procedure, has been used to treat symptomatic genu valgum when the deformity originates in the distal femur. QUESTIONS/PURPOSES: This study aimed to measure the accuracy of lateral opening wedge DFO in achieving deformity correction using radiographic parameters. In addition, the ability of lateral opening wedge DFO to improve patient outcomes as measured by Short Form Health Survey (SF-36) scores and American Academy of Orthopedic Surgeons (AAOS) lower limb module (LLM) scores leading to successful joint preservation was assessed...
July 2017: HSS Journal: the Musculoskeletal Journal of Hospital for Special Surgery
https://www.readbyqxmd.com/read/28657562/patient-specific-instrumentation-in-total-knee-arthroplasty
#17
Andrea Colombelli, Alberto Belluati, Yousef Rizqallah, Giovanni Guerra, Carlo Busatto
BACKGROUND AND AIM OF THE WORK: The international literature and analysis of the prosthetic registers highlight a significant relationship between the alignment of the components and the survival of prosthetic implants of the knee. The patient specific instrumentation (PSI) technology exploits the data obtained with the MRN for the production of cutting blocks (CB) useful to a TKA. Revisiting the recent international literature, comparing the results of the conventional method and PSI, numerous studies confirm a statistically significant difference of inliers (± 3 degrees) for HKA...
June 7, 2017: Acta Bio-medica: Atenei Parmensis
https://www.readbyqxmd.com/read/28635661/hypoxic-preconditioning-promotes-the-bioactivities-of-mesenchymal-stem-cells-via-the-hif-1%C3%AE-grp78-akt-axis
#18
Jun Hee Lee, Yeo Min Yoon, Sang Hun Lee
Mesenchymal stem cells (MSC) are ideal materials for stem cell-based therapy. As MSCs reside in hypoxic microenvironments (low oxygen tension of 1% to 7%), several studies have focused on the beneficial effects of hypoxic preconditioning on MSC survival; however, the mechanisms underlying such effects remain unclear. This study aimed to uncover the potential mechanism involving 78-kDa glucose-regulated protein (GRP78) to explain the enhanced MSC bioactivity and survival in hindlimb ischemia. Under hypoxia (2% O₂), the expression of GRP78 was significantly increased via hypoxia-inducible factor (HIF)-1α...
June 21, 2017: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/28632063/kinetic-analysis-of-the-lower-limbs-in-baseball-tee-batting
#19
Kazumichi Ae, Sekiya Koike, Norihisa Fujii, Michiyoshi Ae, Takashi Kawamura
The purpose of this study was to investigate effects of the ground reaction forces on the rotation of the body as a whole and on the joint torques of the lower limbs associated with trunk and pelvic rotation in baseball tee batting. A total of 22 male collegiate baseball players participated in this study. Three-dimensional coordinate data were acquired by a motion capture system (250 Hz), and ground reaction forces of both legs were measured with three force platforms (1,000 Hz). Kinetic data were used to calculate the moment about the vertical axis through the body's centre of mass resulting from ground reaction forces, as well as to calculate the torque and mechanical work in the lower limb joints...
September 2017: Sports Biomechanics
https://www.readbyqxmd.com/read/28628195/heterogeneity-of-tight-junctions-in-the-thick-ascending-limb
#20
REVIEW
Markus Bleich, Vera C Wulfmeyer, Nina Himmerkus, Susanne Milatz
Renal tubular transport mechanisms are optimized to be energy efficient and tailored to local gradients and transport rates. The combined transcellular action of ion channels, transporters, and pumps, together with the paracellular pathway, enables kidney function. Monogenetic diseases and mouse models indicate that both trans- and paracellular proteins can become disease-causing candidates and may be targets for future therapeutic approaches. Recent advances in tight junction research have provided new insights into their structure, function, and regulation...
June 19, 2017: Annals of the New York Academy of Sciences
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