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Mechanical axis limbs

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https://www.readbyqxmd.com/read/29747561/similar-radiological-results-with-accelerometer-based-navigation-versus-conventional-technique-in-total-knee-arthroplasty
#1
Ing How Moo, Jerry Yong Qiang Chen, Dickson Hong Him Chau, See Wei Tan, Adrian Cheng Kiang Lau, Yee Sze Teo
BACKGROUND: The Zimmer iASSIST system is an accelerometer-based, portable navigation device for total knee arthroplasty (TKA) that does not require the use of a large console for alignment feedback as required in computer-assisted surgery. The purpose of this study was to determine the accuracy of the accelerometer-based system in component positioning and overall mechanical alignment. METHODS: Two groups of 30 patients each with primary osteoarthritis underwent TKA using either conventional method or Zimmer iASSIST navigation in 2013 was retrospectively studied...
May 2018: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/29721334/ectopic-fgf-signaling-induces-the-intercalary-response-in-developing-chicken-limb-buds
#2
Aki Makanae, Akira Satoh
Background: Intercalary pattern formation is an important regulatory step in amphibian limb regeneration. Amphibian limb regeneration is composed of multiple steps, including wounding, blastema formation, and intercalary pattern formation. Attempts have been made to transfer insights from regeneration-competent animals to regeneration-incompetent animalsat each step in the regeneration process. In the present study, we focused on the intercalary mechanism in chick limb buds. In amphibian limb regeneration, a proximodistal axis is organized as soon as a regenerating blastema is induced...
2018: Zoological Letters
https://www.readbyqxmd.com/read/29719716/expression-of-meis-and-hoxa11-in-dipnoan-and-teleost-fins-provides-new-insights-into-the-evolution-of-vertebrate-appendages
#3
Fernanda Langellotto, Maria Fiorentino, Elena De Felice, Luigi Caputi, Valeria Nittoli, Jean M P Joss, Paolo Sordino
Background: The concerted activity of Meis and Hoxa11 transcription factors is essential for the subdivision of tetrapod limbs into proximo-distal (PD) domains; however, little is know about the evolution of this patterning mechanism. Here, we aim to study the expression of meis and hoxa11 orthologues in the median and paired rayed fins of zebrafish and in the lobed fins of the Australian lungfish. Results: First, a late phase of expression of meis1.1 and hoxa11b in zebrafish dorsal and anal fins relates with segmentation of endochondral elements in proximal and distal radials...
2018: EvoDevo
https://www.readbyqxmd.com/read/29615464/coordinated-directional-outgrowth-and-pattern-formation-by-integration-of-wnt5a-and-fgf-signaling-in-planar-cell-polarity
#4
Bo Gao, Rieko Ajima, Wei Yang, Chunyu Li, Hai Song, Matthew J Anderson, Robert R Liu, Mark B Lewandoski, Terry P Yamaguchi, Yingzi Yang
Embryonic morphogenesis of a complex organism requires proper regulation of patterning and directional growth. The Planar Cell Polarity (PCP) signaling is emerging as a critical evolutionarily conserved mechanism whereby directional information is conveyed. PCP is thought to be established by global cues, and recent studies have revealed an instructive role of Wnt signaling gradient in epithelia tissues of both invertebrates and vertebrates. However, it remains unclear whether Wnt/PCP signaling is coordinately regulated with embryonic patterning during morphogenesis...
April 3, 2018: Development
https://www.readbyqxmd.com/read/29595475/multi-view-light-sheet-imaging-and-tracking-with-the-mamut-software-reveals-the-cell-lineage-of-a-direct-developing-arthropod-limb
#5
Carsten Wolff, Jean-Yves Tinevez, Tobias Pietzsch, Evangelia Stamataki, Benjamin Harich, Léo Guignard, Stephan Preibisch, Spencer Shorte, Philipp J Keller, Pavel Tomancak, Anastasios Pavlopoulos
During development, coordinated cell behaviors orchestrate tissue and organ morphogenesis. Detailed descriptions of cell lineages and behaviors provide a powerful framework to elucidate the mechanisms of morphogenesis. To study the cellular basis of limb development, we imaged transgenic fluorescently-labeled embryos from the crustacean Parhyale hawaiensis with multi-view light-sheet microscopy at high spatiotemporal resolution over several days of embryogenesis. The cell lineage of outgrowing thoracic limbs was reconstructed at single-cell resolution with new software called Massive Multi-view Tracker (MaMuT)...
March 29, 2018: ELife
https://www.readbyqxmd.com/read/29576644/complex-tibial-plateau-fractures-treated-by-hybrid-external-fixation-system-a-correlation-of-followup-computed-tomography-derived-quality-of-reduction-with-clinical-results
#6
Konstantinos Kateros, Spyridon P Galanakos, Georgios Kyriakopoulos, Stamatios A Papadakis, George A Macheras
Background: Tibial plateau fractures are common due to high energy injuries. The principles of treatment include respect for the soft tissues, restoring the congruity of the articular surface and reduction of the anatomic alignment of the lower limb to enable early movement of the knee joint. There are various surgical fixation methods that can achieve these principles of treatment. Recognition of the particular fracture pattern is important, as this guides the surgical approach required in order to adequately stabilize the fracture...
March 2018: Indian Journal of Orthopaedics
https://www.readbyqxmd.com/read/29556891/preoperative-tibial-mechanical-axis-orientation-and-articular-surface-design-influence-on-the-coronal-joint-line-orientation-relative-to-the-ground-during-gait-after-total-knee-arthroplasties
#7
Koji Murakami, Satoshi Hamai, Ken Okazaki, Satoru Ikebe, Hidehiko Higaki, Takeshi Shimoto, Yasuharu Nakashima
PURPOSE: Neutral lower limb alignment does not necessarily produce a horizontal joint line after total knee arthroplasty (TKA). The orientation of the pre- and postoperative tibial mechanical axes (TMAs-G), tibial component, and joint line relative to the ground were evaluated. METHODS: The study group included 46 knees, 23 posterior-stabilized (PS) and 23 bicruciate-stabilized (BCS) TKAs. Using whole-leg standing radiographs, the static orientation of the pre- and postoperative TMAs-G and the tibial component as well as the postoperative alignment were measured...
March 20, 2018: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29549568/cozen-s-deformity-resolved-by-guided-growth
#8
Matthew Morin, Joshua Klatt, Peter M Stevens
Proximal tibial metaphyseal fractures in children can lead to progressive and symptomatic tibial valgus. Corrective osteotomy has been abandoned, due to frequent complications, including recurrent valgus deformity. While spontaneous remodelling has been reported, this is not predictable. For children with persistent deformities, we have resorted to guided growth of the tibia. We present 19 patients who were successfully treated with guided growth, tethering the proximal medial physis. There were ten boys and nine girls, ranging in age from two to 13...
March 16, 2018: Strategies in Trauma and Limb Reconstruction
https://www.readbyqxmd.com/read/29506932/current-role-of-computer-navigation-in-total-knee-arthroplasty
#9
Christopher W Jones, Seth A Jerabek
BACKGROUND: Computer-assisted surgical (CAS) navigation has been developed with the aim of improving the accuracy and precision of total knee arthroplasty (TKA) component positioning and therefore overall limb alignment. The historical goal of knee arthroplasty has been to restore the mechanical alignment of the lower limb by aligning the femoral and tibial components perpendicular to the mechanical axis of the femur and tibia. Despite over 4 decades of TKA component development and nearly 2 decades of interest in CAS, the fundamental question remains; does the alignment goal and/or the method of achieving that goal affect the outcome of the TKA in terms of patient-reported outcome measures and/or overall survivorship? The quest for reliable and reproducible achievement of the intraoperative alignment goal has been the primary motivator for the introduction, development, and refinement of CAS navigation...
January 31, 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29497620/anterior-cruciate-ligament-reconstruction-in-skeletally-immature-patients-early-results-using-a-hybrid-physeal-sparing-technique
#10
Robert G Willson, Regina O Kostyun, Matthew D Milewski, Carl W Nissen
Background: Reconstruction of the anterior cruciate ligament (ACL) in the skeletally immature patient is frequently performed in hopes of preventing new or additional chondral damage and meniscal injuries. Patients within a few years of skeletal maturity are more at risk for ACL injuries than prepubescent patients, about whom several physeal-sparing techniques have been described. Reconstruction techniques in the former higher risk group need to be better understood. Purpose: To review a series of adolescent patients with ACL injuries surgically treated with the hybrid physeal-sparing technique...
February 2018: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/29494464/simultaneous-acute-femoral-deformity-correction-and-gradual-limb-lengthening-using-a-retrograde-femoral-nail-technique-and-clinical-results
#11
Christopher A Iobst, S Robert Rozbruch, Scott Nelson, Austin Fragomen
INTRODUCTION: Patients with limb-length discrepancies often have concomitant deformity. We describe the outcomes of acute, fixator-assisted deformity correction with gradual lengthening using the retrograde femoral Precice nail (NuVasive). METHODS: We analyzed a retrospective series of 27 patients in whom an external fixator was combined with a Precice nail to correct angular or rotational deformity and limb-length discrepancy. The fixator was applied temporarily to restore normal alignment...
April 1, 2018: Journal of the American Academy of Orthopaedic Surgeons
https://www.readbyqxmd.com/read/29482301/intentionally-increased-flexion-angle-of-the-femoral-component-in-mobile-bearing-unicompartmental-knee-arthroplasty
#12
Kye-Youl Cho, Kang-Il Kim, Sang-Jun Song, Kyu-Jin Kim
Purpose: The purpose of this study was to determine the results of mobile bearing unicompartmental knee arthroplasty (UKA) with an intentionally increased flexion angle of the femoral component in patients requiring high flexion. Materials and Methods: We investigated 45 knees treated by UKA. Clinically, we measured the range of motion (ROM) and the American Knee Society (AKS) score preoperatively and at final follow-up and investigated complications. Radiologically, we measured the flexion angle of the femoral component, the posterior slope angle of the tibial component, the femorotibial angle and mechanical axis of the limb postoperatively...
March 1, 2018: Knee Surgery & related Research
https://www.readbyqxmd.com/read/29476644/axial-and-cellular-heterogeneity-in-electrolyte-transport-pathways-along-the-thick-ascending-limb
#13
REVIEW
H Dimke, J Schnermann
The thick ascending limb (TAL) extends from the border of the inner medulla to the renal cortex, thus ascending through regions with wide differences in tissue solute and electrolyte concentrations. Structural and functional differences between TAL cells in the medulla (mTAL) and the cortex (cTAL) would therefore be useful to adapt TAL transport function to a changing external fluid composition. While mechanisms common to all TAL cells play a central role in the reclamation of about 25% of the NaCl filtered by the kidney, morphological features, Na+ / K+ -ATPase activity, NKCC2 splicing and phosphorylation do vary between segments and cells...
May 2018: Acta Physiologica
https://www.readbyqxmd.com/read/29426792/twelve-year-follow-up-of-navigated-computer-assisted-versus-conventional-total-knee-arthroplasty-a-prospective-randomized-comparative-trial
#14
Johannes Cip, Florian Obwegeser, Thomas Benesch, Christian Bach, Paul Ruckenstuhl, Arno Martin
BACKGROUND: Navigated computer-assisted total knee arthroplasty (TKA) was introduced to expedite long-term survival based on improved postoperative implantation accuracy. However, long-term outcome data after 10 years or more are rare, even available meta-analyses show controversial study results. METHODS: In a prospective randomized trial, 100 conventional TKAs (group CONV) were compared with 100 computer-assisted TKAs (group NAV) after a mean follow-up of 12 years postoperatively...
May 2018: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29373454/double-oblique-osteotomy-a-technique-for-correction-of-posttraumatic-deformities-of-the-distal-femur
#15
Michael A Miranda, Joseph P DeAngelis, George H Canizares, Jeffery W Mast
OBJECTIVE: To evaluate the outcomes of a double oblique osteotomy for the management of distal femoral malunions and a combination malunion/nonunion. DESIGN: Case series. SETTING: Level 1/2 hospital. PATIENTS/PARTICIPANTS: Ten patients with a mean age of 50 years (range 30-69 years) with posttraumatic deformities of the distal femur. INTERVENTION: A 2-level, length-sparing osteotomy was performed in accordance with a detailed preoperative plan for correction of the mechanical axis in a distal femoral deformity...
February 2018: Journal of Orthopaedic Trauma
https://www.readbyqxmd.com/read/29338847/evaluation-and-validation-of-musculoskeletal-force-feasible-set-indices-application-to-manual-wheelchair-propulsion
#16
Vincent Hernandez, Philippe Gorce, Nasser Rezzoug
The aim of this work was to assess handrim wheelchair propulsion effectiveness, related to the applied forces on the handrim, through the force feasible set. For a given posture of the upper-limb, it represents the set of isometric forces that can be applied on the handrim in any direction. The force feasible set was predicted from a musculoskeletal model of the upper-limb and trunk (10 degrees of freedom and 56 muscles). The aim of the first part of the study was to compare the force feasible set prediction and the force currently applied on the handrim...
February 8, 2018: Journal of Biomechanics
https://www.readbyqxmd.com/read/29216705/-functional-results-of-open-wedge-osteotomies-in-lower-limb-angular-deformities-in-teenagers
#17
C Orellana-Reta, L A Valdez-Jiménez
OBJECTIVE: The aim of this study was to evaluate the functional and radiographic results of adolescent patients with angular deformities of the pelvic limbs treated with an open wedge osteotomy system. MATERIAL AND METHODS: Observational, prospective, analytical and cross-sectional study of patients with angular deformity of the pelvic limbs treated with an open wedge osteotomy. We made a radiographic evaluation of the femorotibial angle, MAD angle, lower limb discrepancy, and pre- and postoperative degrees of the rotational center of deformity (CORA), as well as a telephone survey of the postoperative functional evaluation IKDC 2000...
May 2017: Acta Ortopédica Mexicana
https://www.readbyqxmd.com/read/29204861/kinematically-aligned-total-knee-arthroplasty-reduces-knee-adduction-moment-more-than-mechanically-aligned-total-knee-arthroplasty
#18
Yasuo Niki, Takeo Nagura, Katsuya Nagai, Shu Kobayashi, Kengo Harato
PURPOSE: Knee adduction moment (KAM) has been recognized as a good clinical surrogate for medial tibiofemoral joint loading and is associated with implant durability after total knee arthroplasty (TKA). This study aimed to examine the effects of joint line obliquity in kinematically aligned TKA (KA-TKA) on KAM during gait. METHODS: The study enrolled 21 knees from 18 patients who underwent cylindrical axis reference KA-TKA and a matched group of 21 knees from 18 patients who underwent mechanically aligned (MA)-TKA as controls...
December 4, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/29130040/effect-of-computer-navigation-on-accuracy-and-reliability-of-limb-alignment-correction-following-open-wedge-high-tibial-osteotomy-a-meta-analysis
#19
Seung-Beom Han, Hyun Jung Kim, Dae-Hee Lee
Background: It is unclear whether computer navigation can improve the accuracy and reliability of targeted lower limb alignment correction following open-wedge high tibial osteotomy (HTO). This meta-analysis was designed to compare the accuracy and reliability of limb alignment correction between computer navigated and conventional open-wedge HTOs. Methods: Studies that compared postoperative coronal alignment, including mechanical axis (MA) and weight bearing line (WBL) ratio, outliers of alignment correction, and change in tibial posterior slope, following open-wedge HTO performed using computer navigated and conventional methods were included...
2017: BioMed Research International
https://www.readbyqxmd.com/read/29050180/-meta-analysis-of-three-dimensional-printing-patient-specific-instrumentation-versus-conventional-instrumentation-in-total-knee-arthroplasty
#20
J T Ren, C Xu, J S Wang, X L Liu
Objective: To evaluate the effects of three-dimensional printing patient-specific instrumentation(PSI) versus conventional instrumentation(CI) in the total knee arthroplasty. Methods: According to "patient-specific" , "patient-matched" , "custom" , "Instrumentation" , "Guide Instrumentation" , "cutting blocks" , "total knee arthroplasty" , "total knee replacement" , "TKA" and "TKR" , the literature on PubMed, EMbase, Cochrane library, CBM and WanFang were searched. According to the inclusion and exclusion criteria, the high quality randomized control trial (RCT) studies about three-dimensional (3D) printing patient-specific instrumentation versus conventional instrumentation in the total knee arthroplasty were collected...
October 1, 2017: Zhonghua Wai Ke za Zhi [Chinese Journal of Surgery]
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