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https://www.readbyqxmd.com/read/28432106/prohibitin-induced-obesity-leads-to-anovulation-and-polycystic-ovary-in-mice
#1
Sudharsana Rao Ande, Khanh Hoa Nguyen, Yang Xin Zi Xu, Suresh Mishra
Polycystic ovary syndrome (PCOS) is a prevalent endocrine disorder and the most common cause of female infertility. However, the etiology of the disease and the mechanisms by which this disorder progress remain unclear. Here we report that a transgenic obese mouse (Mito-Ob) developed by overexpressing prohibitin in adipocytes develops polycystic ovaries. Initially, the female Mito-Ob mice were equally fertile to their wild-type littermates. Mito-Ob mice begin to gain weight after puberty, become significantly obese between 3-6 months of age, and roughly 25% of them become infertile by 9 months of age...
April 21, 2017: Biology Open
https://www.readbyqxmd.com/read/28422330/genetic-relationships-among-female-fertility-disorders-female-fertility-traits-and-productivity-of-holstein-dairy-cows-in-the-early-lactation-period
#2
E Gernand, S König
Fertility health disorders from the early lactation period including retained placenta (REPLA), metritis (MET), corpus luteum persistence (CLP), anoestria/acyclia (AOEAC) and ovarial cysts (OC), as well as overall disease categories (disorders during the postpartal period (DPP), ovary infertility (OINF), overall trait definition "fertility disorders" (FD)), were used to estimate genetic (co)variance components with female fertility and test-day traits. The disease data set comprised 25,142 Holstein cows from parities 1, 2 and 3 resulting in 43,584 lactations...
April 19, 2017: Journal of Animal Breeding and Genetics, Zeitschrift Für Tierzüchtung und Züchtungsbiologie
https://www.readbyqxmd.com/read/28412839/awareness-and-knowledge-of-ovarian-cancer-symptoms-and-risk-factors-a-survey-of-jordanian-women
#3
Mazen Freij, Mohammad Al Qadire, Maysa Khadra, Mohammed ALBashtawy, Wael Tuqan, Mohammad Al Faqih, Ayoub Innabi, Abdul-Monim Batiha, Fadwa Alhalaiqa, Aida Abd El-Razek
Ovarian cancer accounts for 3% of all female cancers and has a high mortality rate among gynecological malignancies. Early diagnosis carries a high survival rate of 93%. So, this study was carried out to assess the knowledge and awareness of Jordanian women about ovarian cancer symptoms and risk factors. A cross-sectional survey design was used; 896 women completed the survey. The mean of total symptoms recognized was low at level of 3.2 ( SD = 2.7) out of 10. The three highest known symptoms among women were as follows: extreme fatigue (43...
April 1, 2017: Clinical Nursing Research
https://www.readbyqxmd.com/read/28409048/laparoscopic-reduction-and-closure-of-an-internal-hernia-secondary-to-gynecologic-surgery
#4
Takashi Sakamoto, Alan Kawarai Lefor
Internal hernia is a rare cause of bowel obstruction which often requires emergent surgery. In general, the preoperative diagnosis of internal hernia is difficult. The pelvic cavity has various spaces with the potential to result in a hernia, especially in females. In this report, we describe a patient with an internal hernia secondary to previous gynecologic surgery. A 49-year-old woman presented with acute abdominal pain and a history of previous right oophorectomy for a benign ovarian cyst. Computed tomography scan of the abdomen showed obstruction with strangulation and emergent laparoscopic exploration was performed...
2017: Case Reports in Surgery
https://www.readbyqxmd.com/read/28397199/proliferation-and-maturation-of-intratumoral-blood-vessels-in-women-with-malignant-ovarian-tumors-assessed-with-cancer-stem-cells-marker-nestin-and-platelet-derived-growth-factor-pdgf-b
#5
Sylwia Czekierdowska, Norbert Stachowicz, Mieczysław Chróściel, Artur Czekierdowski
OBJECTIVES: Platelet-derived growth factor B (PDGF-B) and nestin have been suggested to be useful in the assessment of neoangiogenesis in malignant ovarian masses. We aimed to investigate a possible association of these markers with newly formed microcapillaries and perivascular cells in ovarian tumors. MATERIAL AND METHODS: Microvessel density (MVD) and pericytes were studied in 82 women with ovarian neoplasms, including 7 benign cysts, 7 borderline masses, 64 epithelial ovarian cancers and 4 other malignant ovarian tumors...
2017: Ginekologia Polska
https://www.readbyqxmd.com/read/28394114/ovarian-teratoma-in-routine-biopsy-material-during-a-five-year-period
#6
Marina Kos, Jasmina Nikić, Tanja Leniček
Teratomas are tumors derived from germ cells, most frequently arising in the gonads. The aim of this study was to determine the number of ovarian teratomas diagnosed in the routine biopsy material at Ljudevit Jurak Clinical Department of Pathology, Sestre milosrdnice University Hospital Center during a 5-year period, as well as their clinical, gross and microscopic characteristics. Teratomas accounted for 48.6% (n=166) of primary ovarian tumors. The patient mean age was 34.74±12.37 years. Difference in the incidence of teratoma between the left and right ovary was not significant; bilateral teratoma was found in 13 patients...
June 2016: Acta Clinica Croatica
https://www.readbyqxmd.com/read/28390642/a-28-year-old-woman-with-branching-opacity-and-chest-pain
#7
Daniel D Droukas, Stephen C Machnicki
A 28-year-old female patient presented through her primary care physician with symptoms of atypical chest pain and chronic cough. Her pain was described as pleuritic and intermittently radiating to the right arm. Her medical history was significant for recurrent respiratory infections, gastritis, and a left ovarian cyst treated with ipsilateral salpingo-oophorectomy. She denied any history of smoking, known lung disease, or extrapulmonary infections.
April 2017: Chest
https://www.readbyqxmd.com/read/28381238/homozygous-germ-line-mutation-of-the-pms2-mismatch-repair-gene-a-unique-case-report-of-constitutional-mismatch-repair-deficiency-cmmrd
#8
N C Ramchander, N A J Ryan, E J Crosbie, D G Evans
BACKGROUND: Constitutional mismatch repair deficiency syndrome results from bi-allelic inheritance of mutations affecting the key DNA mismatch repair genes: MLH1, MSH2, MSH6 or PMS2. Individuals with bi-allelic mutations have a dysfunctional mismatch repair system from birth; as a result, constitutional mismatch repair deficiency syndrome is characterised by early onset malignancies. Fewer than 150 cases have been reported in the literature over the past 20 years. This is the first report of the founder PMS2 mutation - NM_000535...
April 5, 2017: BMC Medical Genetics
https://www.readbyqxmd.com/read/28378464/luteal-activity-and-effect-of-dietary-energy-restriction-on-follicular-development-in-lactating-cows
#9
A Comin, T Peric, M Montillo, A Cappa, V Marchi, M C Veronesi, A Prandi
The aim of this research has been to evaluate the presence of anomalies in the ovarian cycle activity during postpartum and to verify whether 72-hr dietary fasting during the dominance phase, the phase before ovulation, might modify the ovarian follicle population. The presence of anomalies in ovarian cycle activity has been evaluated in 30 Italian Friesian cows starting from 20 days postpartum until 211 days of lactation. Long oestrus and brief dioestrus or scarce luteal activity have been the main anomalies found through measuring progesterone concentrations in the whey...
April 4, 2017: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/28376925/serum-and-peritoneal-fluid-concentrations-of-soluble-human-leukocyte-antigen-tumor-necrosis-factor-alpha-and-interleukin-10-in-patients-with-selected-ovarian-pathologies
#10
Olimpia Sipak-Szmigiel, Piotr Włodarski, Elżbieta Ronin-Walknowska, Andrzej Niedzielski, Beata Karakiewicz, Sylwia Słuczanowska-Głąbowska, Maria Laszczyńska, Witold Malinowski
BACKGROUND: Although immune system plays a key role in the pathogenesis of both endometriosis and ovarian cancer, its function is different. Therefore, we hypothesized, that selected immune parameters can serve as diagnostic markers of these two conditions. The aim of this study was to compare serum and peritoneal fluid concentrations of sHLA-G, IL-10 and TNF-alpha in women with selected ovarian pathologies: benign serous cysts, endometrioma and malignant tumors. Clinical significance of using them for diagnostic purposes in women with serous ovarian cysts, endometriosis, and ovarian cancer, which in the future may improve the early diagnosis of ovarian diseases...
April 4, 2017: Journal of Ovarian Research
https://www.readbyqxmd.com/read/28357094/high-grade-serous-ovarian-cancer-3-years-after-bilateral-salpingectomy-a-case-report
#11
Emi Sato, Kentaro Nakayama, Masako Ishikawa, Kohei Nakamura, Tomoka Ishibashi, Satoru Kyo
Although epithelial ovarian cancer commonly originates from the ovarian surface epithelium and/or ovarian inclusion cysts, it was recently proposed that high-grade serous ovarian cancer (HGSC) develops from the Fallopian tubes. In our department, we encountered a case of HGSC that contradicts the hypothesis of a tubal origin for HGSC. A 51-year-old postmenopausal woman had undergone hysterectomy, left oophorectomy and bilateral salpingectomy for uterine myoma. Three years later, the patient was diagnosed with stage IV ovarian cancer and underwent primary debulking surgery...
February 2017: Molecular and Clinical Oncology
https://www.readbyqxmd.com/read/28348936/ciprofloxacin-induced-hepatotoxicity-in-a-healthy-young-adult
#12
Zulfiqar Qutrio Baloch, Muhammad Ali Raza, Shabber A Abbas, Sumera Bukhari
Ciprofloxacin is a broad-spectrum fluoroquinolone antibiotic that is widely used in the treatment of many common infections, including urinary tract infections (UTIs). Despite the increase in Escherichia coli resistance to ciprofloxacin, especially in the United States (US), clinicians continue to utilize the high bioavailability of this drug in urine to counter UTIs. A rare adverse effect following use of ciprofloxacin is drug-induced hepatitis. In this case report, we describe a young 29-year-old female with a previous medical history significant for pyelonephritis and ovarian cyst who presented to the emergency room with signs and symptoms suggestive of progressive liver injury for two weeks that started two days after a complete course of ciprofloxacin therapy for a UTI...
February 8, 2017: Curēus
https://www.readbyqxmd.com/read/28348910/a-wandering-abdominal-mass-in-a-neonate-an-enteric-duplication-cyst-mimicking-an-ovarian-cyst
#13
Shigeo Iijima
Enteric duplication cysts are rare congenital anomalies that are prenatally diagnosed through antenatal ultrasonography (US). In female patients, however, attention must be paid since these formations might be confused with ovarian cysts. Herein, we present a case of a low birth weight female infant with an enteric duplication cyst. A cystic lesion was detected in the right abdomen of the fetus on antenatal US and magnetic resonance imaging (MRI). Serial US and MRI examinations performed after birth showed a single cyst that wandered from side to side in the abdomen; the initial diagnosis was thought to be an ovarian cyst...
2017: Case Reports in Pediatrics
https://www.readbyqxmd.com/read/28348779/unusual-case-of-pelvic-hydatid-cyst-of-broad-ligament-mimicking-an-ovarian-tumour
#14
Alaa Abdullah, Reema Alsafi, Jamshaid Iqbal, Vincent Rotimi
INTRODUCTION: The diagnosis of hydatid cyst in female genital tract is rare and difficult. A high degree of clinical suspicion is needed for pre-operative investigations to exclude hydatid cyst of female pelvis. The objective of this presentation is to highlight a pelvic hydatid cyst that presented as an ovarian tumour. CASE PRESENTATION: A 22-year-old female, presented with constipation and haematuria with acute urinary retention. On examination, a mass measuring 15×13 cm was palpable in the left iliac region reaching up to the umbilicus...
August 2016: JMM Case Reports
https://www.readbyqxmd.com/read/28346665/effects-of-ovarian-structures-identified-at-ovsynch%C3%A2-enrolment-disease-history-and-lactation-variables-on-odds-of-pregnancy-to-a-fixed-time-artificial-insemination-after-ovsynch%C3%A2
#15
L Ingenhoff, E Hall, S Ranjbar Ni, J K House
OBJECTIVE: To determine the effects of ovarian structures present at Ovsynch™ enrolment, disease history, lactation variables and times bred on pregnancy per fixed-time artificial insemination (FTAI) following fixed-time insemination after Ovsynch and to determine the relationship between the size of ovarian follicular structures and concurrent presence of a corpus luteum (CL). METHODS: The study was conducted in a 3000-cow Holstein dairy herd. Over a 6-month period, 886 non-pregnant cows were examined by transrectal ultrasound and enrolled into 1132 Ovsynch events...
April 2017: Australian Veterinary Journal
https://www.readbyqxmd.com/read/28336475/intraoperative-rupture-of-ovarian-dermoid-cysts-in-the-pediatric-and-adolescent-population-should-this-change-your-surgical-management
#16
Krista J Childress, Gisselle Perez-Milicua, Julie Hakim, Oluyemisi Adeyemi-Fowode, Jennifer L Bercaw-Pratt, Xiomara M Santos, Jennifer E Dietrich
STUDY OBJECTIVE: 1) To determine the incidence of chemical peritonitis after cystectomy for ovarian dermoid cysts with intraoperative cyst rupture in the pediatric and adolescent population. 2) To examine the intraoperative and postoperative outcomes of cystectomies performed for ovarian dermoid cysts by laparoscopy and laparotomy, especially those with intraoperative cyst rupture. DESIGN: A retrospective cohort study of females who underwent ovarian cystectomy with proven ovarian dermoid pathology between July 2007 and July 2015...
March 20, 2017: Journal of Pediatric and Adolescent Gynecology
https://www.readbyqxmd.com/read/28325358/seromucinous-ovarian-tumor-a-comparison-with-the-rest-of-ovarian-epithelial-tumors
#17
COMPARATIVE STUDY
Georgia Karpathiou, Celine Chauleur, Thomas Corsini, Melany Venet, Cyril Habougit, Freschia Honeyman, Fabien Forest, Michel Peoc'h
BACKGROUND: Seromucinous ovarian tumors are rare and not adequately described in the literature and this is especially true for seromucinous carcinomas. AIM OF THE STUDY: To describe histological and clinical features of these tumors in comparison with the rest of ovarian epithelial tumors. MATERIALS AND METHODS: Two hundred and forty one (241) ovarian tumors, borderline (n=92) or malignant (n=149), treated surgically without neoadjuvant chemotherapy, were examined...
April 2017: Annals of Diagnostic Pathology
https://www.readbyqxmd.com/read/28296829/ovarian-torsion-in-the-normal-ovary-a-diagnostic-challenge-in-postmenarchal-adolescent-girls-in-the-emergency-department
#18
Erbil Karaman, Burhan Beger, Orkun Çetin, Mehmet Melek, Yasemin Karaman
BACKGROUND Ovarian torsion can be seen in the otherwise-normal ovary and is a challenging issue in the emergency department. The aims were (1) to evaluate and compare the surgically verified ovarian torsion cases in otherwise-normal ovaries and ovaries including a mass or cyst and (2) to investigate whether the normal-appearing ovaries on ultrasound examination affected the diagnosis of ovarian torsion or not. MATERIAL AND METHODS A retrospective cohort study design was used. The medical records of all postmenarchal adolescent girls with surgically verified ovarian torsion treated in a university hospital from 2010 to 2016 were reviewed...
March 15, 2017: Medical Science Monitor: International Medical Journal of Experimental and Clinical Research
https://www.readbyqxmd.com/read/28293058/ruptured-hemorrhagic-cyst-of-undescended-ovary-mimicking-mucocele-a-rare-pediatric-case
#19
Tamer Sekmenli, Metin Gündüz, Ilhan Ciftci
Undescended ovary is a rare entity and usually presentedas a case report. It is associated with urinary and uterine anomalies. Symptomatic patients are diagnosed during surgery. Most of the patients are asymptomatic and treatment is unnecessary. They are incidentally diagnosed during infertility evaluation and treatment such as ovarian hyperstimulation studies. A 15-year-old female patient presented with the diagnosis of renal cystic massas identifiedduring ultrasonography in another hospital. Abdominal computedtomography image was requested...
January 2017: Iranian Journal of Medical Sciences
https://www.readbyqxmd.com/read/28288674/cytochrome%C3%A2-p450-oxidoreductase-deficiency-caused-by-r457h-mutation-in-por-gene-in-chinese-case-report-and-literature-review
#20
REVIEW
Yang Bai, Jinhui Li, Xiaoli Wang
BACKGROUND: Cytochrome P450 oxidoreductase deficiency (PORD) is a rare disease exhibiting a variety of clinical manifestations. It can be difficult to differentiate with other diseases such as 21-hydroxylase deficiency (21-OHD), polycystic ovary syndrome (PCOS) and Antley-Bixler syndrome (ABS). Nearly 100 cases of PORD have been reported worldwide. However, the genetic characters and clinical management are still unclear, especially in China. CASE PRESENTATION: In this study, we report a 27-year-old female Chinese patient who first presented with amenorrhea and recurrence of large ovary cyst...
March 14, 2017: Journal of Ovarian Research
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