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Sherlock Holmes

Richard J Johnson
Epidemics of chronic kidney disease are now recognized in Central America, Mexico, India and Sri Lanka, and there is also some evidence that similar epidemics may be occurring in the USA, Thailand and elsewhere. A common denominator for each location is manually working outside in extremely hot environments. Here we review the evidence that the primary etiology may be heat stress related to repeated subclinical or clinical acute kidney injury that eventually manifests as chronic kidney disease. In some aspects, the disease may manifest as subclinical heat stroke, subclinical rhabdomyolysis or a subclinical tumor lysis syndrome...
April 1, 2017: Nephrology, Dialysis, Transplantation
Durgadas P Kasbekar
No abstract text is available yet for this article.
March 2017: Journal of Biosciences
Leslie Mertz
"It is a capital mistake to theorize before one has data," said Sherlock Holmes creator and author Arthur Conan Doyle in 1887. In this era of big data, and especially the crush of medical information becoming available through new technologies and bulging databases, Doyle's quote could be updated to: "It is a capital mistake to theorize before one has data and understands what they mean."
September 2016: IEEE Pulse
Yaolin Zheng, Paul O Wilkinson
No abstract text is available yet for this article.
August 2016: British Journal of Psychiatry: the Journal of Mental Science
Ali J Marian
No abstract text is available yet for this article.
June 24, 2016: Circulation Research
Ambika Gopalakrishnan Unnikrishnan, Sanjay Kalra
No abstract text is available yet for this article.
January 2016: Indian Journal of Endocrinology and Metabolism
(no author information available yet)
My favorite painter is Pablo Picasso. My favorite book is The Complete Sherlock Holmes.
November 11, 2015: Angewandte Chemie
Wenjie Wu, Elizabeth Sheppard, Peter Mitchell
Mentalizing (otherwise known as 'theory of mind') involves a special process that is adapted for predicting and explaining the behaviour of others (targets) based on inferences about targets' beliefs and character. This research investigated how well participants made inferences about an especially apposite aspect of character, empathy. Participants were invited to make inferences of self-rated empathy after watching or listening to an unfamiliar target for a few seconds telling a scripted joke (or answering questions about him/herself or reading aloud a paragraph of promotional material)...
February 2016: British Journal of Psychology
Andrew J Lees
No abstract text is available yet for this article.
July 2015: Brain: a Journal of Neurology
L H B Baur, W M J Schreurs, H R van Leeuwen-Wintjes, C L Berendsen, R Willems, R A G Winkens, R Vliegen, P Theunissen, E B Gomez Garcia
The purpose of this case report is to describe a rare case of a patient with a phaeochromocytoma with several cardiovascular complications, which can be attributed to the tumour. Detection of a phaeochromocytoma sometimes needs a 'Sherlock Holmes spirit' or simply time.
July 2015: Netherlands Heart Journal
Paul H McCabe
No abstract text is available yet for this article.
April 2015: Epilepsy & Behavior: E&B
Robert J Joynt, Peter A Kempster, Andrew J Lee
After the death in 2012 of Dr. Robert Joynt, who served Neurology® as CPC Section Editor, an unfinished manuscript was found on his computer. It would have been his sixth Sherlock Holmes pastiche. Intrigued by the story but deflated at the lack of an ending, the editors published the case in the September 10, 2013, issue of Neurology and requested that readers finish it. A panel of editors reviewed over 30 submissions and the top 4 were posted online and on the iPad. Readers voted online, on the iPad, and during the 2014 American Academy of Neurology Annual Meeting in Philadelphia...
August 12, 2014: Neurology
Brenda Moore-McCann
Semiotics is the analysis and interpretation of signs and the basis of medicine since antiquity. It is suggested that the growth of technology has led to the virtual eclipse of the clinical examination with consequent loss of skill, empathy and patient trust. This paper views the value of medical semiotics through the method of the 19th century Italian doctor, Giovanni Morelli, which has had a significant but little recognised impact on the early development of psychoanalysis, the detective novel and art connoisseurship...
November 2016: Journal of Medical Biography
Vincent J Cirillo
When the Anglo-Boer War broke out in October 1899, Arthur Conan Doyle, a retired ophthalmologist, was already famous as the creator of Sherlock Holmes. Motivated by patriotism and adventure, Doyle joined the medical staff of a private field hospital endowed by philanthropist John Langman (1846-1928). Langman Hospital opened in Bloemfontein, South Africa, at the height of that city's typhoid fever epidemic which raged from April to June 1900. There were nearly 5000 cases of typhoid and 1000 deaths but official statistics do not truly reflect the magnitude of the suffering...
February 2014: Journal of Medical Biography
B Sopeña
This article lists the integral elements of the Sherlock Holmes method, which is based on the intelligent collection of information through detailed observation, careful listening and thorough examination. The information thus obtained is analyzed to develop the main and alternative hypotheses, which are shaped during the deductive process until the key leading to the solution is revealed. The Holmes investigative method applied to clinical practice highlights the advisability of having physicians reason through and seek out the causes of the disease with the data obtained from acute observation, a detailed review of the medical history and careful physical examination...
April 2014: Revista Clínica Espanõla
A Schattner
No abstract text is available yet for this article.
December 2013: QJM: Monthly Journal of the Association of Physicians
Peter A Kempster, Andrew J Lees
When searching for clues to reach a diagnosis, neurologists often empathise with the detective who is trying to solve a case. The premise of this article is that detective stories have been part of the fabric of neurology ever since the time that it evolved into a discrete medical speciality. We will examine how this form of narrative has found expression in detective mystery fiction and popular science publications created by 20th century neurologist physician-writers. We will also investigate the power of the neurologist's alter ego, Sherlock Holmes: his relationship to founders of clinical neuroscience such as Jean-Martin Charcot, William Gowers and Sigmund Freud, and his influences on neurological practice and its literary traditions...
December 2013: Practical Neurology
Eftychios Siniorakis, Spyridon Arvanitakis, Nikos Pantelis, Georgios Bokos, Nikodimos Giannakopoulos, Apostolos Balanis, Sotiria Limberi
No abstract text is available yet for this article.
October 12, 2013: International Journal of Cardiology
J Reed
The adventures of Sherlock Holmes, although primarily famous as stories of detection of crime, offer a considerable amount to interest the medical reader. There are many medical references in the stories, and the influence of Conan Doyle's medical background is clearly seen in the main characters. Aspects of the stories also reflect Conan Doyle's medical career, and also something of his attitude towards the profession. From Holmes's sayings and accounts of his methods, parallels can be drawn between Holmesian deduction and the diagnostic process...
December 2001: Medical Humanities
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