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Sherlock Holmes

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https://www.readbyqxmd.com/read/29094697/crime-fiction-sherlock-holmes-a-family-likeness
#1
Eric L Altschuler
No abstract text is available yet for this article.
November 1, 2017: Nature
https://www.readbyqxmd.com/read/29023267/enhanced-th17-responses-in-patients-with-il10-receptor-deficiency-and-infantile-onset-ibd
#2
Dror S Shouval, Liza Konnikova, Alexandra E Griffith, Sarah M Wall, Amlan Biswas, Lael Werner, Moran Nunberg, Jochen Kammermeier, Jeremy A Goettel, Rajsavi Anand, Hannah Chen, Batia Weiss, Jian Li, Anthony Loizides, Baruch Yerushalmi, Tadahiro Yanagi, Rita Beier, Laurie S Conklin, Christen L Ebens, Fernanda G M S Santos, Mary Sherlock, Jeffery D Goldsmith, Daniel Kotlarz, Sarah C Glover, Neil Shah, Athos Bousvaros, Holm H Uhlig, Aleixo M Muise, Christoph Klein, Scott B Snapper
BACKGROUND: IL10 receptor (IL10R) deficiency causes severe infantile-onset inflammatory bowel disease. Intact IL10R-dependent signals have been shown to be important for innate and adaptive immune cell functions in mice. We have previously reported a key role of IL10 in the generation and function of human anti-inflammatory macrophages. Independent of innate immune cell defects, the aim of the current study was to determine the role of IL10R signaling in regulating human CD4 T-cell function...
November 2017: Inflammatory Bowel Diseases
https://www.readbyqxmd.com/read/28933428/fiction-the-science-in-sherlock-holmes
#3
Maria Konnikova
No abstract text is available yet for this article.
September 20, 2017: Nature
https://www.readbyqxmd.com/read/28713755/tumor-induced-osteomalacia-a-sherlock-holmes-approach-to-diagnosis-and-management
#4
G V Chanukya, Manoj Mengade, Jagadishwar Goud, I Satish Rao, Anuj Jain
Tumor-induced osteomalacia (TIO) is a subtype of paraneoplastic syndrome associated with hypophosphatemia due to renal phosphate wasting in adults. The humoral factor responsible for clinical picture known as fibroblast growth factor 23 (FGF23) is most often secreted by benign yet elusive mesenchymal tumors, difficult to localize, access, and excise completely; rarely, they are multiple and malignant. Paradoxical inappropriately normal or low levels of 1,25-dihydroxyvitamin D in the setting of hypophosphatemia is due to suppressive effect of FGF23...
January 2017: Annals of Maxillofacial Surgery
https://www.readbyqxmd.com/read/28407135/pro-heat-stress-as-a-potential-etiology-of-mesoamerican-and-sri-lankan-nephropathy-a-late-night-consult-with-sherlock-holmes
#5
Richard J Johnson
Epidemics of chronic kidney disease are now recognized in Central America, Mexico, India and Sri Lanka, and there is also some evidence that similar epidemics may be occurring in the USA, Thailand and elsewhere. A common denominator for each location is manually working outside in extremely hot environments. Here we review the evidence that the primary etiology may be heat stress related to repeated subclinical or clinical acute kidney injury that eventually manifests as chronic kidney disease. In some aspects, the disease may manifest as subclinical heat stroke, subclinical rhabdomyolysis or a subclinical tumor lysis syndrome...
April 1, 2017: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/28229959/sherlock-holmes-david-perkins-and-the-missing-neurospora-inversions
#6
Durgadas P Kasbekar
No abstract text is available yet for this article.
March 2017: Journal of Biosciences
https://www.readbyqxmd.com/read/28113168/what-can-big-data-tell-us-about-health-finding-gold-through-data-mining
#7
Leslie Mertz
"It is a capital mistake to theorize before one has data," said Sherlock Holmes creator and author Arthur Conan Doyle in 1887. In this era of big data, and especially the crush of medical information becoming available through new technologies and bulging databases, Doyle's quote could be updated to: "It is a capital mistake to theorize before one has data and understands what they mean."
September 2016: IEEE Pulse
https://www.readbyqxmd.com/read/27482039/sherlock-holmes-the-case-of-the-man-with-the-mistaken-diagnosis-psychiatry-in-literature
#8
Yaolin Zheng, Paul O Wilkinson
No abstract text is available yet for this article.
August 2016: British Journal of Psychiatry: the Journal of Mental Science
https://www.readbyqxmd.com/read/27340268/the-case-of-missing-causal-genes-and-the-practice-of-medicine-a-sherlock-holmes-approach-of-deductive-reasoning
#9
Ali J Marian
No abstract text is available yet for this article.
June 24, 2016: Circulation Research
https://www.readbyqxmd.com/read/26904461/endocrinology-evidence-and-sherlock-holmes
#10
Ambika Gopalakrishnan Unnikrishnan, Sanjay Kalra
No abstract text is available yet for this article.
January 2016: Indian Journal of Endocrinology and Metabolism
https://www.readbyqxmd.com/read/26555097/haoshen-zhou
#11
(no author information available yet)
My favorite painter is Pablo Picasso. My favorite book is The Complete Sherlock Holmes.
November 11, 2015: Angewandte Chemie
https://www.readbyqxmd.com/read/26531895/being-sherlock-holmes-can-we-sense-empathy-from-a-brief-sample-of-behaviour
#12
Wenjie Wu, Elizabeth Sheppard, Peter Mitchell
Mentalizing (otherwise known as 'theory of mind') involves a special process that is adapted for predicting and explaining the behaviour of others (targets) based on inferences about targets' beliefs and character. This research investigated how well participants made inferences about an especially apposite aspect of character, empathy. Participants were invited to make inferences of self-rated empathy after watching or listening to an unfamiliar target for a few seconds telling a scripted joke (or answering questions about him/herself or reading aloud a paragraph of promotional material)...
February 2016: British Journal of Psychology
https://www.readbyqxmd.com/read/26041612/the-strange-case-of-dr-william-gowers-and-mr-sherlock-holmes
#13
Andrew J Lees
No abstract text is available yet for this article.
July 2015: Brain: a Journal of Neurology
https://www.readbyqxmd.com/read/26031635/a-white-raven-detected-by-imaging
#14
L H B Baur, W M J Schreurs, H R van Leeuwen-Wintjes, C L Berendsen, R Willems, R A G Winkens, R Vliegen, P Theunissen, E B Gomez Garcia
The purpose of this case report is to describe a rare case of a patient with a phaeochromocytoma with several cardiovascular complications, which can be attributed to the tumour. Detection of a phaeochromocytoma sometimes needs a 'Sherlock Holmes spirit' or simply time.
July 2015: Netherlands Heart Journal
https://www.readbyqxmd.com/read/25769675/would-sherlock-holmes-agree-with-our-definition-of-rational-polytherapy-a-proposal-for-a-national-data-bank-on-patients-with-epilepsy
#15
EDITORIAL
Paul H McCabe
No abstract text is available yet for this article.
April 2015: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/25254262/reflections-neurology-and-the-humanities-the-case-of-the-locked-house-the-finished-mystery
#16
Robert J Joynt, Peter A Kempster, Andrew J Lee
After the death in 2012 of Dr. Robert Joynt, who served Neurology® as CPC Section Editor, an unfinished manuscript was found on his computer. It would have been his sixth Sherlock Holmes pastiche. Intrigued by the story but deflated at the lack of an ending, the editors published the case in the September 10, 2013, issue of Neurology and requested that readers finish it. A panel of editors reviewed over 30 submissions and the top 4 were posted online and on the iPad. Readers voted online, on the iPad, and during the 2014 American Academy of Neurology Annual Meeting in Philadelphia...
August 12, 2014: Neurology
https://www.readbyqxmd.com/read/24986397/medical-semiotics-its-influence-on-art-psychoanalysis-and-sherlock-holmes
#17
Brenda Moore-McCann
Semiotics is the analysis and interpretation of signs and the basis of medicine since antiquity. It is suggested that the growth of technology has led to the virtual eclipse of the clinical examination with consequent loss of skill, empathy and patient trust. This paper views the value of medical semiotics through the method of the 19th century Italian doctor, Giovanni Morelli, which has had a significant but little recognised impact on the early development of psychoanalysis, the detective novel and art connoisseurship...
November 2016: Journal of Medical Biography
https://www.readbyqxmd.com/read/24585840/arthur-conan-doyle-1859-1930-physician-during-the-typhoid-epidemic-in-the-anglo-boer-war-1899-1902
#18
Vincent J Cirillo
When the Anglo-Boer War broke out in October 1899, Arthur Conan Doyle, a retired ophthalmologist, was already famous as the creator of Sherlock Holmes. Motivated by patriotism and adventure, Doyle joined the medical staff of a private field hospital endowed by philanthropist John Langman (1846-1928). Langman Hospital opened in Bloemfontein, South Africa, at the height of that city's typhoid fever epidemic which raged from April to June 1900. There were nearly 5000 cases of typhoid and 1000 deaths but official statistics do not truly reflect the magnitude of the suffering...
February 2014: Journal of Medical Biography
https://www.readbyqxmd.com/read/24457141/the-sherlock-holmes-method-in-clinical-practice
#19
B Sopeña
This article lists the integral elements of the Sherlock Holmes method, which is based on the intelligent collection of information through detailed observation, careful listening and thorough examination. The information thus obtained is analyzed to develop the main and alternative hypotheses, which are shaped during the deductive process until the key leading to the solution is revealed. The Holmes investigative method applied to clinical practice highlights the advisability of having physicians reason through and seek out the causes of the disease with the data obtained from acute observation, a detailed review of the medical history and careful physical examination...
April 2014: Revista Clínica Espanõla
https://www.readbyqxmd.com/read/24131548/sherlock-holmes-and-clinical-excellence
#20
LETTER
A Schattner
No abstract text is available yet for this article.
December 2013: QJM: Monthly Journal of the Association of Physicians
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