keyword
MENU ▼
Read by QxMD icon Read
search

Fecal microbiota

keyword
https://www.readbyqxmd.com/read/28815345/mosapride-stabilizes-intestinal-microbiota-to-reduce-bacterial-translocation-and-endotoxemia-in-ccl4-induced-cirrhotic-rats
#1
Hong Xu, Jingfang Xiong, Jianjun Xu, Shuiming Li, Yang Zhou, Dongya Chen, Xinjun Cai, Jian Ping, Min Deng, Jianyong Chen
BACKGROUND: Impaired intestinal motility may lead to the disruption of gut microbiota equilibrium, which in turn facilitates bacterial translocation (BT) and endotoxemia in cirrhosis. We evaluated the influence of mosapride, a prokinetic agent, on BT and DNA fingerprints of gut microbiota in cirrhotic rats. METHODS: A rat model of cirrhosis was set up via subcutaneous injection of carbon tetrachloride (CCl4). The portal pressure, liver and intestinal damage, plasma endotoxin, BT, and intestinal transit rate (ITR) of cirrhotic rats were determined...
August 16, 2017: Digestive Diseases and Sciences
https://www.readbyqxmd.com/read/28815303/effect-of-barley-supplementation-on-the-fecal-microbiota-caecal-biochemistry-and-key-biomarkers-of-obesity-and-inflammation-in-obese-db-db-mice
#2
Jose F Garcia-Mazcorro, David A Mills, Kevin Murphy, Giuliana Noratto
PURPOSE: Barley is a low-glycemic index grain that can help diabetic and obese patients. The effect of barley intake depends on the host and the associated gut microbiota. This study investigated the effect of barley intake on the fecal microbiota, caecal biochemistry, and key biomarkers of obesity and inflammation. METHODS: Obese db/db mice were fed diets with and without barley during 8 weeks; lean mice were used as lean controls. Fecal microbiota was evaluated using 16S marker gene sequencing in a MiSeq instrument; several markers of caecal biochemistry, obesity, and inflammation were also evaluated using standard techniques...
August 16, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28814395/fecal-concentrations-of-bacterially-derived-vitamin-k-forms-are-associated-with-gut-microbiota-composition-but-not-plasma-or-fecal-cytokine-concentrations-in-healthy-adults
#3
J Philip Karl, Mohsen Meydani, Junaidah B Barnett, Sally M Vanegas, Kathryn Barger, Xueyan Fu, Barry Goldin, Anne Kane, Helen Rasmussen, Pajau Vangay, Dan Knights, Satya S Jonnalagadda, Edward Saltzman, Susan B Roberts, Simin N Meydani, Sarah L Booth
Background: Emerging evidence suggests novel roles for bacterially derived vitamin K forms known as menaquinones in health and disease, which may be attributable in part to anti-inflammatory effects. However, the relevance of menaquinones produced by gut bacteria to vitamin K requirements and inflammation is undetermined.Objective: This study aimed to quantify fecal menaquinone concentrations and identify associations between fecal menaquinone concentrations and serum vitamin K concentrations, gut microbiota composition, and inflammation...
August 16, 2017: American Journal of Clinical Nutrition
https://www.readbyqxmd.com/read/28811841/bacteriophages-in-the-gastrointestinal-tract-and-their-implications
#4
Marzanna Łusiak-Szelachowska, Beata Weber-Dąbrowska, Ewa Jończyk-Matysiak, Renata Wojciechowska, Andrzej Górski
The gut microbiota plays an essential role in health and disease of humans. Bacteriophages are the most abundant members of the gut virobiota and display great diversity. Phages can translocate through the mucosa to lymph and internal organs and play a role as regulators of the bacterial population in the gut. Increasing abundance of phages in the gut mucosa may reduce colonization by bacteria. Moreover, phages may have an immunomodulatory role in the immune response in the human gut. The role of phages in inflammatory bowel disease (IBD) remains unknown...
2017: Gut Pathogens
https://www.readbyqxmd.com/read/28808547/patterns-of-seasonality-and-group-membership-characterize-the-gut-microbiota-in-a-longitudinal-study-of-wild-verreaux-s-sifakas-propithecus-verreauxi
#5
Andrea Springer, Claudia Fichtel, Gabriel A Al-Ghalith, Flávia Koch, Katherine R Amato, Jonathan B Clayton, Dan Knights, Peter M Kappeler
The intestinal microbiota plays a major role in host development, metabolism, and health. To date, few longitudinal studies have investigated the causes and consequences of microbiota variation in wildlife, although such studies provide a comparative context for interpreting the adaptive significance of findings from studies on humans or captive animals. Here, we investigate the impact of seasonality, diet, group membership, sex, age, and reproductive state on gut microbiota composition in a wild population of group-living, frugi-folivorous primates, Verreaux's sifakas (Propithecus verreauxi)...
August 2017: Ecology and Evolution
https://www.readbyqxmd.com/read/28807067/iterative-fecal-microbiota-transplantations-for-eradicating-digestive-colonization-with-carbapenemase-producing-enterobacteriaceae-is-it-worth-it
#6
Rafael Mahieu, Viviane Cassisa, Diane Sanderink, Rachel Chenouard, Hélène Pailhoriès, Marie Kempf, Vincent Dubée, Matthieu Eveillard
No abstract text is available yet for this article.
August 15, 2017: Infection Control and Hospital Epidemiology
https://www.readbyqxmd.com/read/28803549/comparative-gut-microbiota-and-resistome-profiling-of-intensive-care-patients-receiving-selective-digestive-tract-decontamination-and-healthy-subjects
#7
Elena Buelow, Teresita D J Bello González, Susana Fuentes, Wouter A A de Steenhuijsen Piters, Leo Lahti, Jumamurat R Bayjanov, Eline A M Majoor, Johanna C Braat, Maaike S M van Mourik, Evelien A N Oostdijk, Rob J L Willems, Marc J M Bonten, Mark W J van Passel, Hauke Smidt, Willem van Schaik
BACKGROUND: The gut microbiota is a reservoir of opportunistic pathogens that can cause life-threatening infections in critically ill patients during their stay in an intensive care unit (ICU). To suppress gut colonization with opportunistic pathogens, a prophylactic antibiotic regimen, termed "selective decontamination of the digestive tract" (SDD), is used in some countries where it improves clinical outcome in ICU patients. Yet, the impact of ICU hospitalization and SDD on the gut microbiota remains largely unknown...
August 14, 2017: Microbiome
https://www.readbyqxmd.com/read/28801639/investigation-into-the-stability-and-culturability-of-chinese-enterotypes
#8
Yeshi Yin, Bin Fan, Wei Liu, Rongrong Ren, Huahai Chen, Shaofeng Bai, Liying Zhu, Gang Sun, Yunsheng Yang, Xin Wang
Although many gut microbial enterotypes have been reported in Europe, Africa and the U.S., their effects on human health are still not yet clear. Culturing gut microbial enterotypes in vitro will be helpful to study their effects and applications. Here, fecal samples from 13 healthy Chinese volunteers were collected and subjected to next-generation sequencing. The results showed that seven of these samples belong to the Bacteroides enterotype and another six to the Prevotella enterotype. Stability of these Chinese gut microbial enterotypes was also evaluated...
August 11, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28801119/stability-and-efficacy-of-frozen-and-lyophilized-fecal-microbiota-transplant-fmt-product-in-a-mouse-model-of-clostridium-difficile-infection-cdi
#9
Zhi-Dong Jiang, Ashley Alexander, Shi Ke, Evangelia M Valilis, Shaofan Hu, Bingjie Li, Herbert L DuPont
Freezing donor fecal microbiota has simplified fecal microbiota transplantation (FMT) in the treatment of recurrent C. difficile infection (CDI). However, the optimal storage time for the frozen FMT products remains unknown. Using an established murine model of CDI, stability and efficacy of frozen and lyophilized FMT product was studied at time points from 2 months to 15 months. DNA was extracted from fecal samples from the mice with identification of specific bacterial species by real-time quantitative PCR (qPCR)...
August 9, 2017: Anaerobe
https://www.readbyqxmd.com/read/28796069/assessment-of-therapeutic-response-in-crohn-s-disease-using-quantitative-dynamic-contrast-enhanced-mri-dce-mri-parameters-a-preliminary-study
#10
Jianguo Zhu, Faming Zhang, Jinfa Zhou, Haige Li
The aim of the study was to investigate dynamic contrast enhanced MRI (DCE-MRI) as a potential marker to assess the therapeutic responses of fecal microbiota transplantation (FMT) in patients with Crohn's disease (CD) and to determine the parameter or combination of parameters most strongly associated with changes in clinical indicators after treatment.In 22 CD patients, DCE-MRI was performed with a 3.0T scanner. Parameters of DCE-MRI (vascular transfer constant [K] and blood volume [BV]) in the terminal ileum were compared between before and day 90 after FMT treatment...
August 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28793975/infant-gut-microbiome-associated-with-cognitive%C3%A2-development
#11
Alexander L Carlson, Kai Xia, M Andrea Azcarate-Peril, Barbara D Goldman, Mihye Ahn, Martin A Styner, Amanda L Thompson, Xiujuan Geng, John H Gilmore, Rebecca C Knickmeyer
BACKGROUND: Studies in rodents provide compelling evidence that microorganisms inhabiting the gut influence neurodevelopment. In particular, experimental manipulations that alter intestinal microbiota impact exploratory and communicative behaviors and cognitive performance. In humans, the first years of life are a dynamic time in gut colonization and brain development, but little is known about the relationship between these two processes. METHODS: We tested whether microbial composition at 1 year of age is associated with cognitive outcomes using the Mullen Scales of Early Learning and with global and regional brain volumes using structural magnetic resonance imaging at 1 and 2 years of age...
June 27, 2017: Biological Psychiatry
https://www.readbyqxmd.com/read/28791008/free-fatty-acids-profiles-are-related-to-gut-microbiota-signatures-and-short-chain-fatty-acids
#12
Javier Rodríguez-Carrio, Nuria Salazar, Abelardo Margolles, Sonia González, Miguel Gueimonde, Clara G de Los Reyes-Gavilán, Ana Suárez
A growing body of evidence highlights the relevance of free fatty acids (FFA) for human health, and their role in the cross talk between the metabolic status and immune system. Altered serum FFA profiles are related to several metabolic conditions, although the underlying mechanisms remain unclear. Recent studies have highlighted the link between gut microbiota and host metabolism. However, although most of the studies have focused on different clinical conditions, evidence on the role of these mediators in healthy populations is lacking...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28790981/determination-of-resistant-starch-assimilating-bacteria-in-fecal-samples-of-mice-by-in-vitro-rna-based-stable-isotope-probing
#13
Elena Herrmann, Wayne Young, Douglas Rosendale, Ralf Conrad, Christian U Riedel, Markus Egert
The impact of the intestinal microbiota on human health is becoming increasingly appreciated in recent years. In consequence, and fueled by major technological advances, the composition of the intestinal microbiota in health and disease has been intensively studied by high throughput sequencing approaches. Observations linking dysbiosis of the intestinal microbiota with a number of serious medical conditions including chronic inflammatory disorders and allergic diseases suggest that restoration of the composition and activity of the intestinal microbiota may be a treatment option at least for some of these diseases...
2017: Frontiers in Microbiology
https://www.readbyqxmd.com/read/28790923/gut-microbiome-response-to-sucralose-and-its-potential-role-in-inducing-liver-inflammation-in-mice
#14
Xiaoming Bian, Liang Chi, Bei Gao, Pengcheng Tu, Hongyu Ru, Kun Lu
Sucralose is the most widely used artificial sweetener, and its health effects have been highly debated over the years. In particular, previous studies have shown that sucralose consumption can alter the gut microbiota. The gut microbiome plays a key role in processes related to host health, such as food digestion and fermentation, immune cell development, and enteric nervous system regulation. Inflammation is one of the most common effects associated with gut microbiome dysbiosis, which has been linked to a series of human diseases, such as diabetes and obesity...
2017: Frontiers in Physiology
https://www.readbyqxmd.com/read/28789710/transplanted-human-fecal-microbiota-enhanced-guillain-barr%C3%A3-syndrome-autoantibody-responses-after-campylobacter-jejuni-infection-in-c57bl-6-mice
#15
Phillip T Brooks, Kelsey A Brakel, Julia A Bell, Christopher E Bejcek, Trey Gilpin, Jean M Brudvig, Linda S Mansfield
BACKGROUND: Campylobacter jejuni is the leading antecedent infection to the autoimmune neuropathy Guillain-Barré syndrome (GBS), which is accompanied by an autoimmune anti-ganglioside antibody attack on peripheral nerves. Previously, we showed that contrasting immune responses mediate C. jejuni induced colitis and autoimmunity in interleukin-10 (IL-10)-deficient mice, dependent upon the infecting strain. Strains from colitis patients elicited T helper 1 (TH1)-dependent inflammatory responses while strains from GBS patients elicited TH2-dependent autoantibody production...
August 8, 2017: Microbiome
https://www.readbyqxmd.com/read/28789705/impact-of-intrapartum-antimicrobial-prophylaxis-upon-the-intestinal-microbiota-and-the-prevalence-of-antibiotic-resistance-genes-in-vaginally-delivered-full-term-neonates
#16
Alicja Nogacka, Nuria Salazar, Marta Suárez, Christian Milani, Silvia Arboleya, Gonzalo Solís, Nuria Fernández, Lidia Alaez, Ana M Hernández-Barranco, Clara G de Los Reyes-Gavilán, Marco Ventura, Miguel Gueimonde
BACKGROUND: Disturbances in the early establishment of the intestinal microbiota may produce important implications for the infant's health and for the risk of disease later on. Different perinatal conditions may be affecting the development of the gut microbiota. Some of them, such as delivery mode or feeding habits, have been extensively assessed whereas others remain to be studied, being critical to identify their impact on the microbiota and, if any, to minimize it. Antibiotics are among the drugs most frequently used in early life, the use of intrapartum antimicrobial prophylaxis (IAP), present in over 30% of deliveries, being the most frequent source of exposure...
August 8, 2017: Microbiome
https://www.readbyqxmd.com/read/28782784/lactobacillus-casei-ccfm419-attenuates-type-2-diabetes-via-a-gut-microbiota-dependent-mechanism
#17
Gang Wang, Xiangfei Li, Jianxin Zhao, Hao Zhang, Wei Chen
Probiotics, as dietary supplements, transmit their major effects through the regulation of gut microbiota. According to a previous study, one possible mechanism of Lactobacillus casei CCFM419 protection against diabetes may involve gut flora. To test this hypothesis, high fat and streptozotocin-induced C57BL/6J mice were fed L. casei CCFM419 at 10(8), 10(9), and 10(10) colony forming units (CFU). Compared to untreated mice, 10(9) CFU of L. casei CCFM419 attenuated several symptoms of diabetes, including fasting blood glucose, postprandial blood glucose, glucose intolerance, and insulin resistance...
August 7, 2017: Food & Function
https://www.readbyqxmd.com/read/28781770/long-term-effects-of-early-antibiotic-intervention-on-blood-parameters-apparent-nutrient-digestibility-and-fecal-microbial-fermentation-profile-in-pigs-with-different-dietary-protein-levels
#18
Miao Yu, Chuanjian Zhang, Yuxiang Yang, Chunlong Mu, Yong Su, Kaifan Yu, Weiyun Zhu
BACKGROUD: This study aimed to determine the effects of early antibiotic intervention (EAI) on subsequent blood parameters, apparent nutrient digestibility, and fecal fermentation profile in pigs with different dietary crude protein (CP) levels. Eighteen litters of piglets (total 212) were randomly allocated to 2 groups and were fed a creep feed diet with or without in-feed antibiotics (olaquindox, oxytetracycline calcium and kitasamycin) from postnatal d 7 to d 42. On d 42, the piglets within the control or antibiotic group were mixed, respectively, and then further randomly assigned to a normal- (20%, 18%, and 14% CP from d 42 to d 77, d 77 to d 120, and d 120 to d 185, respectively) or a low-CP diet (16%, 14%, and 10% CP from d 42 to d 77, d 77 to d 120, and d 120 to d 185, respectively), generating 4 groups...
2017: Journal of Animal Science and Biotechnology
https://www.readbyqxmd.com/read/28771910/fecal-markers-of-inflammation-protein-loss-and-microbial-changes-in-dogs-with-the-acute-hemorrhagic-diarrhea-syndrome-ahds
#19
Romy M Heilmann, Melissa M Guard, Jörg M Steiner, Jan S Suchodolski, Stefan Unterer
BACKGROUND: Idiopathic acute hemorrhagic diarrhea syndrome (AHDS) is characterized by acute onset of bloody diarrhea, severe dehydration, and increased vascular and intestinal mucosal permeability. Markers of gastrointestinal inflammation, protein loss, and changes in the intestinal microbiota have not been studied extensively in dogs with AHDS. KEY FINDINGS: For 3 consecutive days, feces were collected from dogs with AHDS, and assayed for calprotectin and S100A12 (both markers of inflammation), α1 -proteinase inhibitor (a marker of gastrointestinal protein loss), and the presence of selected species of bacteria...
August 3, 2017: Journal of Veterinary Emergency and Critical Care
https://www.readbyqxmd.com/read/28771188/apigenin-impacts-the-growth-of-the-gut-microbiota-and-alters-the-gene-expression-of-enterococcus
#20
Minqian Wang, Jenni Firrman, Liqing Zhang, Gustavo Arango-Argoty, Peggy Tomasula, LinShu Liu, Weidong Xiao, Kit Yam
Apigenin is a major dietary flavonoid with many bioactivities, widely distributed in plants. Apigenin reaches the colon region intact and interacts there with the human gut microbiota, however there is little research on how apigenin affects the gut bacteria. This study investigated the effect of pure apigenin on human gut bacteria, at both the single strain and community levels. The effect of apigenin on the single gut bacteria strains Bacteroides galacturonicus, Bifidobacterium catenulatum, Lactobacillus rhamnosus GG, and Enterococcus caccae, was examined by measuring their anaerobic growth profiles...
August 3, 2017: Molecules: a Journal of Synthetic Chemistry and Natural Product Chemistry
keyword
keyword
64114
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"