Tian-jian Ren, Zhong-cheng Wang, Ya-zhuo Zhang, Dan Li, Hong-yun Wang, Zhen-zong Li
BACKGROUND: Treating intramedullary spinal cord gliomas is a big challenge because of limited options, high recurrence rate and poor prognosis. An intramedullary glioma model is prerequisite for testing new treatments. This paper describes the establishment of a rodent intramedullary glioma model and presents functional progression, neuroimaging and histopathological characterization of the tumour model. METHODS: Fischer344 rats (n = 24) were randomized into two groups...
September 2010: Chinese Medical Journal