keyword
https://read.qxmd.com/read/38471765/diagnosis-and-management-in-rubinstein-taybi-syndrome-first-international-consensus-statement
#21
REVIEW
Didier Lacombe, Agnès Bloch-Zupan, Cecilie Bredrup, Edward B Cooper, Sofia Douzgou Houge, Sixto García-Miñaúr, Hülya Kayserili, Lidia Larizza, Vanesa Lopez Gonzalez, Leonie A Menke, Donatella Milani, Francesco Saettini, Cathy A Stevens, Lloyd Tooke, Jill A Van der Zee, Maria M Van Genderen, Julien Van-Gils, Jane Waite, Jean-Louis Adrien, Oliver Bartsch, Pierre Bitoun, Antonia H M Bouts, Anna M Cueto-González, Elena Dominguez-Garrido, Floor A Duijkers, Patricia Fergelot, Elisabeth Halstead, Sylvia A Huisman, Camilla Meossi, Jo Mullins, Sarah M Nikkel, Chris Oliver, Elisabetta Prada, Alessandra Rei, Ilka Riddle, Cristina Rodriguez-Fonseca, Rebecca Rodríguez Pena, Janet Russell, Alicia Saba, Fernando Santos-Simarro, Brittany N Simpson, David F Smith, Markus F Stevens, Katalin Szakszon, Emmanuelle Taupiac, Nadia Totaro, Irene Valenzuena Palafoll, Daniëlle C M Van Der Kaay, Michiel P Van Wijk, Klea Vyshka, Susan Wiley, Raoul C Hennekam
Rubinstein-Taybi syndrome (RTS) is an archetypical genetic syndrome that is characterised by intellectual disability, well-defined facial features, distal limb anomalies and atypical growth, among numerous other signs and symptoms. It is caused by variants in either of two genes ( CREBBP , EP300 ) which encode for the proteins CBP and p300, which both have a function in transcription regulation and histone acetylation. As a group of international experts and national support groups dedicated to the syndrome, we realised that marked heterogeneity currently exists in clinical and molecular diagnostic approaches and care practices in various parts of the world...
March 12, 2024: Journal of Medical Genetics
https://read.qxmd.com/read/38471186/edge-illumination-spectral-phase-contrast-tomography
#22
JOURNAL ARTICLE
Luca Brombal, Fulvia Arfelli, Francesco Brun, Vittorio Di Trapani, Marco Endrizzi, Ralf Menk, Paola Perion, Luigi Rigon, Mara Saccomano, Giuliana Tromba, Alessandro Olivo
Following the rapid, but independent, diffusion of X-ray spectral and phase-contrast systems, this work demonstrates the first combination of spectral and phase-contrast computed tomography (CT) obtained by using the edge-illumination technique and a CdTe small-pixel (62 μm) spectral detector. A theoretical model is introduced, starting from a standard attenuation-based spectral decomposition and leading to spectral phase-contrast material decomposition. Each step of the model is followed by quantification of accuracy and sensitivity on experimental data of a test phantom containing different solutions with known concentrations...
March 12, 2024: Physics in Medicine and Biology
https://read.qxmd.com/read/38470552/preimplantation-genetic-testing-for-monogenic-disorders-pgt-m-offers-an-alternative-strategy-to-prevent-children-from-being-born-with-hereditary-neurological-diseases-or-metabolic-diseases-dominated-by-nervous-system-phenotypes-a-retrospective-study
#23
JOURNAL ARTICLE
Weiwei Zou, Min Li, Xiaolei Wang, Hedong Lu, Yan Hao, Dawei Chen, Shasha Zhu, Dongmei Ji, Zhiguo Zhang, Ping Zhou, Yunxia Cao
BACKGROUND: Preimplantation genetic testing for monogenic disorders (PGT-M) is now widely used as an effective strategy to prevent various monogenic or chromosomal diseases. MATERIAL AND METHODS: In this retrospective study, couples with a family history of hereditary neurological diseases or metabolic diseases dominated by nervous system phenotypes and/or carrying the pathogenic genes underwent PGT-M to prevent children from inheriting disease-causing gene mutations from their parents and developing known genetic diseases...
March 12, 2024: Journal of Assisted Reproduction and Genetics
https://read.qxmd.com/read/38466415/physical-fitness-in-children-with-marfan-and-loeys-dietz-syndrome-associations-between-cardiovascular-parameters-systemic-manifestations-fatigue-and-pain
#24
JOURNAL ARTICLE
Jessica Warnink-Kavelaars, Lisanne E de Koning, Annelies E van der Hulst, Annemieke I Buizer, Nicole Poissonnier, Laura E Wijninga, Leonie A Menke, Laura Muiño Mosquera, Lies Rombaut, Raoul H H Engelbert
Children with Marfan (MFS) and Loeys-Dietz syndrome (LDS) report limitations in physical activities, sports, school, leisure, and work participation in daily life. This observational, cross-sectional, multicenter study explores associations between physical fitness and cardiovascular parameters, systemic manifestations, fatigue, and pain in children with MFS and LDS. Forty-two participants, aged 6-18 years (mean (SD) 11.5(3.7)), diagnosed with MFS (n = 36) or LDS (n = 6), were enrolled...
March 11, 2024: European Journal of Pediatrics
https://read.qxmd.com/read/38457710/search-for-new-phenomena-in-two-body-invariant-mass-distributions-using-unsupervised-machine-learning-for-anomaly-detection-at-sqrt-s-13%C3%A2-%C3%A2-tev-with-the-atlas-detector
#25
JOURNAL ARTICLE
G Aad, B Abbott, K Abeling, N J Abicht, S H Abidi, A Aboulhorma, H Abramowicz, H Abreu, Y Abulaiti, A C Abusleme Hoffman, B S Acharya, C Adam Bourdarios, L Adamczyk, L Adamek, S V Addepalli, M J Addison, J Adelman, A Adiguzel, T Adye, A A Affolder, Y Afik, M N Agaras, J Agarwala, A Aggarwal, C Agheorghiesei, A Ahmad, F Ahmadov, W S Ahmed, S Ahuja, X Ai, G Aielli, A Aikot, M Ait Tamlihat, B Aitbenchikh, I Aizenberg, M Akbiyik, T P A Åkesson, A V Akimov, D Akiyama, N N Akolkar, K Al Khoury, G L Alberghi, J Albert, P Albicocco, G L Albouy, S Alderweireldt, M Aleksa, I N Aleksandrov, C Alexa, T Alexopoulos, F Alfonsi, M Algren, M Alhroob, B Ali, H M J Ali, S Ali, S W Alibocus, M Aliev, G Alimonti, W Alkakhi, C Allaire, B M M Allbrooke, J F Allen, C A Allendes Flores, P P Allport, A Aloisio, F Alonso, C Alpigiani, M Alvarez Estevez, A Alvarez Fernandez, M Alves Cardoso, M G Alviggi, M Aly, Y Amaral Coutinho, A Ambler, C Amelung, M Amerl, C G Ames, D Amidei, S P Amor Dos Santos, K R Amos, V Ananiev, C Anastopoulos, T Andeen, J K Anders, S Y Andrean, A Andreazza, S Angelidakis, A Angerami, A V Anisenkov, A Annovi, C Antel, M T Anthony, E Antipov, M Antonelli, F Anulli, M Aoki, T Aoki, J A Aparisi Pozo, M A Aparo, L Aperio Bella, C Appelt, A Apyan, N Aranzabal, C Arcangeletti, A T H Arce, E Arena, J-F Arguin, S Argyropoulos, J-H Arling, O Arnaez, H Arnold, G Artoni, H Asada, K Asai, S Asai, N A Asbah, J Assahsah, K Assamagan, R Astalos, S Atashi, R J Atkin, M Atkinson, H Atmani, P A Atmasiddha, K Augsten, S Auricchio, A D Auriol, V A Austrup, G Avolio, K Axiotis, G Azuelos, D Babal, H Bachacou, K Bachas, A Bachiu, F Backman, A Badea, P Bagnaia, M Bahmani, A J Bailey, V R Bailey, J T Baines, L Baines, C Bakalis, O K Baker, E Bakos, D Bakshi Gupta, V Balakrishnan, R Balasubramanian, E M Baldin, P Balek, E Ballabene, F Balli, L M Baltes, W K Balunas, J Balz, E Banas, M Bandieramonte, A Bandyopadhyay, S Bansal, L Barak, M Barakat, E L Barberio, D Barberis, M Barbero, K N Barends, T Barillari, M-S Barisits, T Barklow, P Baron, D A Baron Moreno, A Baroncelli, G Barone, A J Barr, J D Barr, L Barranco Navarro, F Barreiro, J Barreiro Guimarães da Costa, U Barron, M G Barros Teixeira, S Barsov, F Bartels, R Bartoldus, A E Barton, P Bartos, A Basan, M Baselga, A Bassalat, M J Basso, C R Basson, R L Bates, S Batlamous, J R Batley, B Batool, M Battaglia, D Battulga, M Bauce, M Bauer, P Bauer, L T Bazzano Hurrell, J B Beacham, T Beau, P H Beauchemin, F Becherer, P Bechtle, H P Beck, K Becker, A J Beddall, V A Bednyakov, C P Bee, L J Beemster, T A Beermann, M Begalli, M Begel, A Behera, J K Behr, J F Beirer, F Beisiegel, M Belfkir, G Bella, L Bellagamba, A Bellerive, P Bellos, K Beloborodov, N L Belyaev, D Benchekroun, F Bendebba, Y Benhammou, M Benoit, J R Bensinger, S Bentvelsen, L Beresford, M Beretta, E Bergeaas Kuutmann, N Berger, B Bergmann, J Beringer, G Bernardi, C Bernius, F U Bernlochner, F Bernon, T Berry, P Berta, A Berthold, I A Bertram, S Bethke, A Betti, A J Bevan, M Bhamjee, S Bhatta, D S Bhattacharya, P Bhattarai, V S Bhopatkar, R Bi, R M Bianchi, G Bianco, O Biebel, R Bielski, M Biglietti, T R V Billoud, M Bindi, A Bingul, C Bini, A Biondini, C J Birch-Sykes, G A Bird, M Birman, M Biros, S Biryukov, T Bisanz, E Bisceglie, J P Biswal, D Biswas, A Bitadze, K Bjørke, I Bloch, C Blocker, A Blue, U Blumenschein, J Blumenthal, G J Bobbink, V S Bobrovnikov, M Boehler, B Boehm, D Bogavac, A G Bogdanchikov, C Bohm, V Boisvert, P Bokan, T Bold, M Bomben, M Bona, M Boonekamp, C D Booth, A G Borbély, I S Bordulev, H M Borecka-Bielska, L S Borgna, G Borissov, D Bortoletto, D Boscherini, M Bosman, J D Bossio Sola, K Bouaouda, N Bouchhar, J Boudreau, E V Bouhova-Thacker, D Boumediene, R Bouquet, A Boveia, J Boyd, D Boye, I R Boyko, J Bracinik, N Brahimi, G Brandt, O Brandt, F Braren, B Brau, J E Brau, R Brener, L Brenner, R Brenner, S Bressler, D Britton, D Britzger, I Brock, G Brooijmans, W K Brooks, E Brost, L M Brown, L E Bruce, T L Bruckler, P A Bruckman de Renstrom, B Brüers, A Bruni, G Bruni, M Bruschi, N Bruscino, T Buanes, Q Buat, D Buchin, A G Buckley, O Bulekov, B A Bullard, S Burdin, C D Burgard, A M Burger, B Burghgrave, O Burlayenko, J T P Burr, C D Burton, J C Burzynski, E L Busch, V Büscher, P J Bussey, J M Butler, C M Buttar, J M Butterworth, W Buttinger, C J Buxo Vazquez, A R Buzykaev, S Cabrera Urbán, L Cadamuro, D Caforio, H Cai, Y Cai, V M M Cairo, O Cakir, N Calace, P Calafiura, G Calderini, P Calfayan, G Callea, L P Caloba, D Calvet, S Calvet, T P Calvet, M Calvetti, R Camacho Toro, S Camarda, D Camarero Munoz, P Camarri, M T Camerlingo, D Cameron, C Camincher, M Campanelli, A Camplani, V Canale, A Canesse, J Cantero, Y Cao, F Capocasa, M Capua, A Carbone, R Cardarelli, J C J Cardenas, F Cardillo, T Carli, G Carlino, J I Carlotto, B T Carlson, E M Carlson, L Carminati, A Carnelli, M Carnesale, S Caron, E Carquin, S Carrá, G Carratta, F Carrio Argos, J W S Carter, T M Carter, M P Casado, M Caspar, E G Castiglia, F L Castillo, L Castillo Garcia, V Castillo Gimenez, N F Castro, A Catinaccio, J R Catmore, V Cavaliere, N Cavalli, V Cavasinni, Y C Cekmecelioglu, E Celebi, F Celli, M S Centonze, V Cepaitis, K Cerny, A S Cerqueira, A Cerri, L Cerrito, F Cerutti, B Cervato, A Cervelli, G Cesarini, S A Cetin, Z Chadi, D Chakraborty, J Chan, W Y Chan, J D Chapman, E Chapon, B Chargeishvili, D G Charlton, T P Charman, M Chatterjee, C Chauhan, S Chekanov, S V Chekulaev, G A Chelkov, A Chen, B Chen, B Chen, H Chen, H Chen, J Chen, J Chen, M Chen, S Chen, S J Chen, X Chen, X Chen, Y Chen, C L Cheng, H C Cheng, S Cheong, A Cheplakov, E Cheremushkina, E Cherepanova, R Cherkaoui El Moursli, E Cheu, K Cheung, L Chevalier, V Chiarella, G Chiarelli, N Chiedde, G Chiodini, A S Chisholm, A Chitan, M Chitishvili, M V Chizhov, K Choi, A R Chomont, Y Chou, E Y S Chow, T Chowdhury, K L Chu, M C Chu, X Chu, J Chudoba, J J Chwastowski, D Cieri, K M Ciesla, V Cindro, A Ciocio, F Cirotto, Z H Citron, M Citterio, D A Ciubotaru, B M Ciungu, A Clark, P J Clark, J M Clavijo Columbie, S E Clawson, C Clement, J Clercx, L Clissa, Y Coadou, M Cobal, A Coccaro, R F Coelho Barrue, R Coelho Lopes De Sa, S Coelli, H Cohen, A E C Coimbra, B Cole, J Collot, P Conde Muiño, M P Connell, S H Connell, I A Connelly, E I Conroy, F Conventi, H G Cooke, A M Cooper-Sarkar, A Cordeiro Oudot Choi, F Cormier, L D Corpe, M Corradi, F Corriveau, A Cortes-Gonzalez, M J Costa, F Costanza, D Costanzo, B M Cote, G Cowan, K Cranmer, D Cremonini, S Crépé-Renaudin, F Crescioli, M Cristinziani, M Cristoforetti, V Croft, J E Crosby, G Crosetti, A Cueto, T Cuhadar Donszelmann, H Cui, Z Cui, W R Cunningham, F Curcio, P Czodrowski, M M Czurylo, M J Da Cunha Sargedas De Sousa, J V Da Fonseca Pinto, C Da Via, W Dabrowski, T Dado, S Dahbi, T Dai, D Dal Santo, C Dallapiccola, M Dam, G D'amen, V D'Amico, J Damp, J R Dandoy, M F Daneri, M Danninger, V Dao, G Darbo, S Darmora, S J Das, S D'Auria, C David, T Davidek, B Davis-Purcell, I Dawson, H A Day-Hall, K De, R De Asmundis, N De Biase, S De Castro, N De Groot, P de Jong, H De la Torre, A De Maria, A De Salvo, U De Sanctis, A De Santo, J B De Vivie De Regie, D V Dedovich, J Degens, A M Deiana, F Del Corso, J Del Peso, F Del Rio, F Deliot, C M Delitzsch, M Della Pietra, D Della Volpe, A Dell'Acqua, L Dell'Asta, M Delmastro, P A Delsart, S Demers, M Demichev, S P Denisov, L D'Eramo, D Derendarz, F Derue, P Dervan, K Desch, C Deutsch, F A Di Bello, A Di Ciaccio, L Di Ciaccio, A Di Domenico, C Di Donato, A Di Girolamo, G Di Gregorio, A Di Luca, B Di Micco, R Di Nardo, C Diaconu, M Diamantopoulou, F A Dias, T Dias Do Vale, M A Diaz, F G Diaz Capriles, M Didenko, E B Diehl, L Diehl, S Díez Cornell, C Diez Pardos, C Dimitriadi, A Dimitrievska, J Dingfelder, I-M Dinu, S J Dittmeier, F Dittus, F Djama, T Djobava, J I Djuvsland, C Doglioni, A Dohnalova, J Dolejsi, Z Dolezal, K M Dona, M Donadelli, B Dong, J Donini, A D'Onofrio, M D'Onofrio, J Dopke, A Doria, N Dos Santos Fernandes, P Dougan, M T Dova, A T Doyle, M A Draguet, E Dreyer, I Drivas-Koulouris, A S Drobac, M Drozdova, D Du, T A du Pree, F Dubinin, M Dubovsky, E Duchovni, G Duckeck, O A Ducu, D Duda, A Dudarev, E R Duden, M D'uffizi, L Duflot, M Dührssen, C Dülsen, A E Dumitriu, M Dunford, S Dungs, K Dunne, A Duperrin, H Duran Yildiz, M Düren, A Durglishvili, B L Dwyer, G I Dyckes, M Dyndal, S Dysch, B S Dziedzic, Z O Earnshaw, G H Eberwein, B Eckerova, S Eggebrecht, E Egidio Purcino De Souza, L F Ehrke, G Eigen, K Einsweiler, T Ekelof, P A Ekman, S El Farkh, Y El Ghazali, H El Jarrari, A El Moussaouy, V Ellajosyula, M Ellert, F Ellinghaus, A A Elliot, N Ellis, J Elmsheuser, M Elsing, D Emeliyanov, Y Enari, I Ene, S Epari, J Erdmann, P A Erland, M Errenst, M Escalier, C Escobar, E Etzion, G Evans, H Evans, L S Evans, M O Evans, A Ezhilov, S Ezzarqtouni, F Fabbri, L Fabbri, G Facini, V Fadeyev, R M Fakhrutdinov, S Falciano, L F Falda Ulhoa Coelho, P J Falke, J Faltova, C Fan, Y Fan, Y Fang, M Fanti, M Faraj, Z Farazpay, A Farbin, A Farilla, T Farooque, S M Farrington, F Fassi, D Fassouliotis, M Faucci Giannelli, W J Fawcett, L Fayard, P Federic, P Federicova, O L Fedin, G Fedotov, M Feickert, L Feligioni, D E Fellers, C Feng, M Feng, Z Feng, M J Fenton, A B Fenyuk, L Ferencz, R A M Ferguson, S I Fernandez Luengo, M J V Fernoux, J Ferrando, A Ferrari, P Ferrari, R Ferrari, D Ferrere, C Ferretti, F Fiedler, A Filipčič, E K Filmer, F Filthaut, M C N Fiolhais, L Fiorini, W C Fisher, T Fitschen, P M Fitzhugh, I Fleck, P Fleischmann, T Flick, M Flores, L R Flores Castillo, L Flores Sanz De Acedo, F M Follega, N Fomin, J H Foo, B C Forland, A Formica, A C Forti, E Fortin, A W Fortman, M G Foti, L Fountas, D Fournier, H Fox, P Francavilla, S Francescato, S Franchellucci, M Franchini, S Franchino, D Francis, L Franco, L Franconi, M Franklin, G Frattari, A C Freegard, W S Freund, Y Y Frid, J Friend, N Fritzsche, A Froch, D Froidevaux, J A Frost, Y Fu, M Fujimoto, E Fullana Torregrosa, K Y Fung, E Furtado De Simas Filho, M Furukawa, J Fuster, A Gabrielli, A Gabrielli, P Gadow, G Gagliardi, L G Gagnon, E J Gallas, B J Gallop, K K Gan, S Ganguly, J Gao, Y Gao, F M Garay Walls, B Garcia, C García, A Garcia Alonso, A G Garcia Caffaro, J E García Navarro, M Garcia-Sciveres, G L Gardner, R W Gardner, N Garelli, D Garg, R B Garg, J M Gargan, C A Garner, S J Gasiorowski, P Gaspar, G Gaudio, V Gautam, P Gauzzi, I L Gavrilenko, A Gavrilyuk, C Gay, G Gaycken, E N Gazis, A A Geanta, C M Gee, C Gemme, M H Genest, S Gentile, A D Gentry, S George, W F George, T Geralis, P Gessinger-Befurt, M E Geyik, M Ghani, M Ghneimat, K Ghorbanian, A Ghosal, A Ghosh, A Ghosh, B Giacobbe, S Giagu, T Giani, P Giannetti, A Giannini, S M Gibson, M Gignac, D T Gil, A K Gilbert, B J Gilbert, D Gillberg, G Gilles, N E K Gillwald, L Ginabat, D M Gingrich, M P Giordani, P F Giraud, G Giugliarelli, D Giugni, F Giuli, I Gkialas, L K Gladilin, C Glasman, G R Gledhill, G Glemža, M Glisic, I Gnesi, Y Go, M Goblirsch-Kolb, B Gocke, D Godin, B Gokturk, S Goldfarb, T Golling, M G D Gololo, D Golubkov, J P Gombas, A Gomes, G Gomes Da Silva, A J Gomez Delegido, R Gonçalo, G Gonella, L Gonella, A Gongadze, F Gonnella, J L Gonski, R Y González Andana, S González de la Hoz, S Gonzalez Fernandez, R Gonzalez Lopez, C Gonzalez Renteria, M V Gonzalez Rodrigues, R Gonzalez Suarez, S Gonzalez-Sevilla, G R Gonzalvo Rodriguez, L Goossens, B Gorini, E Gorini, A Gorišek, T C Gosart, A T Goshaw, M I Gostkin, S Goswami, C A Gottardo, S A Gotz, M Gouighri, V Goumarre, A G Goussiou, N Govender, I Grabowska-Bold, K Graham, E Gramstad, S Grancagnolo, M Grandi, C M Grant, P M Gravila, F G Gravili, H M Gray, M Greco, C Grefe, I M Gregor, P Grenier, C Grieco, A A Grillo, K Grimm, S Grinstein, J-F Grivaz, E Gross, J Grosse-Knetter, C Grud, J C Grundy, L Guan, W Guan, C Gubbels, J G R Guerrero Rojas, G Guerrieri, F Guescini, R Gugel, J A M Guhit, A Guida, T Guillemin, E Guilloton, S Guindon, F Guo, J Guo, L Guo, Y Guo, R Gupta, S Gurbuz, S S Gurdasani, G Gustavino, M Guth, P Gutierrez, L F Gutierrez Zagazeta, C Gutschow, C Gwenlan, C B Gwilliam, E S Haaland, A Haas, M Habedank, C Haber, H K Hadavand, A Hadef, S Hadzic, J J Hahn, E H Haines, M Haleem, J Haley, J J Hall, G D Hallewell, L Halser, K Hamano, M Hamer, G N Hamity, E J Hampshire, J Han, K Han, L Han, L Han, S Han, Y F Han, K Hanagaki, M Hance, D A Hangal, H Hanif, M D Hank, R Hankache, J B Hansen, J D Hansen, P H Hansen, K Hara, D Harada, T Harenberg, S Harkusha, M L Harris, Y T Harris, J Harrison, N M Harrison, P F Harrison, N M Hartman, N M Hartmann, Y Hasegawa, A Hasib, S Haug, R Hauser, C M Hawkes, R J Hawkings, Y Hayashi, S Hayashida, D Hayden, C Hayes, R L Hayes, C P Hays, J M Hays, H S Hayward, F He, M He, Y He, Y He, N B Heatley, V Hedberg, A L Heggelund, N D Hehir, C Heidegger, K K Heidegger, W D Heidorn, J Heilman, S Heim, T Heim, J G Heinlein, J J Heinrich, L Heinrich, J Hejbal, L Helary, A Held, S Hellesund, C M Helling, S Hellman, R C W Henderson, L Henkelmann, A M Henriques Correia, H Herde, Y Hernández Jiménez, L M Herrmann, T Herrmann, G Herten, R Hertenberger, L Hervas, M E Hesping, N P Hessey, H Hibi, S J Hillier, J R Hinds, F Hinterkeuser, M Hirose, S Hirose, D Hirschbuehl, T G Hitchings, B Hiti, J Hobbs, R Hobincu, N Hod, M C Hodgkinson, B H Hodkinson, A Hoecker, J Hofer, T Holm, M Holzbock, L B A H Hommels, B P Honan, J Hong, T M Hong, B H Hooberman, W H Hopkins, Y Horii, S Hou, A S Howard, J Howarth, J Hoya, M Hrabovsky, A Hrynevich, T Hryn'ova, P J Hsu, S-C Hsu, Q Hu, Y F Hu, S Huang, X Huang, Y Huang, Y Huang, Z Huang, Z Hubacek, M Huebner, F Huegging, T B Huffman, C A Hugli, M Huhtinen, S K Huiberts, R Hulsken, N Huseynov, J Huston, J Huth, R Hyneman, G Iacobucci, G Iakovidis, I Ibragimov, L Iconomidou-Fayard, P Iengo, R Iguchi, T Iizawa, Y Ikegami, N Ilic, H Imam, M Ince Lezki, T Ingebretsen Carlson, G Introzzi, M Iodice, V Ippolito, R K Irwin, M Ishino, W Islam, C Issever, S Istin, H Ito, J M Iturbe Ponce, R Iuppa, A Ivina, J M Izen, V Izzo, P Jacka, P Jackson, R M Jacobs, B P Jaeger, C S Jagfeld, P Jain, G Jäkel, K Jakobs, T Jakoubek, J Jamieson, K W Janas, M Javurkova, F Jeanneau, L Jeanty, J Jejelava, P Jenni, C E Jessiman, S Jézéquel, C Jia, J Jia, X Jia, X Jia, Z Jia, Y Jiang, S Jiggins, J Jimenez Pena, S Jin, A Jinaru, O Jinnouchi, P Johansson, K A Johns, J W Johnson, D M Jones, E Jones, P Jones, R W L Jones, T J Jones, H L Joos, R Joshi, J Jovicevic, X Ju, J J Junggeburth, T Junkermann, A Juste Rozas, M K Juzek, S Kabana, A Kaczmarska, M Kado, H Kagan, M Kagan, A Kahn, A Kahn, C Kahra, T Kaji, E Kajomovitz, N Kakati, I Kalaitzidou, C W Kalderon, A Kamenshchikov, N J Kang, D Kar, K Karava, M J Kareem, E Karentzos, I Karkanias, O Karkout, S N Karpov, Z M Karpova, V Kartvelishvili, A N Karyukhin, E Kasimi, J Katzy, S Kaur, K Kawade, M P Kawale, T Kawamoto, E F Kay, F I Kaya, S Kazakos, V F Kazanin, Y Ke, J M Keaveney, R Keeler, G V 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Terashi, J Terron, S Terzo, M Testa, R J Teuscher, A Thaler, O Theiner, N Themistokleous, T Theveneaux-Pelzer, O Thielmann, D W Thomas, J P Thomas, E A Thompson, P D Thompson, E Thomson, Y Tian, V Tikhomirov, Yu A Tikhonov, S Timoshenko, D Timoshyn, E X L Ting, P Tipton, S H Tlou, A Tnourji, K Todome, S Todorova-Nova, S Todt, M Togawa, J Tojo, S Tokár, K Tokushuku, O Toldaiev, R Tombs, M Tomoto, L Tompkins, K W Topolnicki, E Torrence, H Torres, E Torró Pastor, M Toscani, C Tosciri, M Tost, D R Tovey, A Traeet, I S Trandafir, T Trefzger, A Tricoli, I M Trigger, S Trincaz-Duvoid, D A Trischuk, B Trocmé, C Troncon, L Truong, M Trzebinski, A Trzupek, F Tsai, M Tsai, A Tsiamis, P V Tsiareshka, S Tsigaridas, A Tsirigotis, V Tsiskaridze, E G Tskhadadze, M Tsopoulou, Y Tsujikawa, I I Tsukerman, V Tsulaia, S Tsuno, O Tsur, K Tsuri, D Tsybychev, Y Tu, A Tudorache, V Tudorache, A N Tuna, S Turchikhin, I Turk Cakir, R Turra, T Turtuvshin, P M Tuts, S Tzamarias, P Tzanis, E Tzovara, F Ukegawa, P A Ulloa Poblete, E N Umaka, G Unal, M Unal, A Undrus, G Unel, J Urban, P Urquijo, G Usai, R Ushioda, M Usman, Z Uysal, L Vacavant, V Vacek, B Vachon, K O H Vadla, T Vafeiadis, A Vaitkus, C Valderanis, E Valdes Santurio, M Valente, S Valentinetti, A Valero, E Valiente Moreno, A Vallier, J A Valls Ferrer, D R Van Arneman, T R Van Daalen, A Van Der Graaf, P Van Gemmeren, M Van Rijnbach, S Van Stroud, I Van Vulpen, M Vanadia, W Vandelli, M Vandenbroucke, E R Vandewall, D Vannicola, L Vannoli, R Vari, E W Varnes, C Varni, T Varol, D Varouchas, L Varriale, K E Varvell, M E Vasile, L Vaslin, G A Vasquez, A Vasyukov, F Vazeille, T Vazquez Schroeder, J Veatch, V Vecchio, M J Veen, I Veliscek, L M Veloce, F Veloso, S Veneziano, A Ventura, S Ventura Gonzalez, A Verbytskyi, M Verducci, C Vergis, M Verissimo De Araujo, W Verkerke, J C Vermeulen, C Vernieri, M Vessella, M C Vetterli, A Vgenopoulos, N Viaux Maira, T Vickey, O E Vickey Boeriu, G H A Viehhauser, L Vigani, M Villa, M Villaplana Perez, E M Villhauer, E Vilucchi, M G Vincter, G S Virdee, A Vishwakarma, A Visibile, C Vittori, I Vivarelli, V Vladimirov, E Voevodina, F Vogel, P Vokac, Yu Volkotrub, J Von Ahnen, E Von Toerne, B Vormwald, V Vorobel, K Vorobev, M Vos, K Voss, J H Vossebeld, M Vozak, L Vozdecky, N Vranjes, M Vranjes Milosavljevic, M Vreeswijk, R Vuillermet, O Vujinovic, I Vukotic, S Wada, C Wagner, J M Wagner, W Wagner, S Wahdan, H Wahlberg, M Wakida, J Walder, R Walker, W Walkowiak, A Wall, T Wamorkar, A Z Wang, C Wang, C Wang, H Wang, J Wang, R-J Wang, R Wang, R Wang, S M Wang, S Wang, T Wang, W T Wang, W Wang, X Wang, X Wang, X Wang, Y Wang, Y Wang, Z Wang, Z Wang, Z Wang, A Warburton, R J Ward, N Warrack, A T Watson, H Watson, M F Watson, E Watton, G Watts, B M Waugh, C Weber, H A Weber, M S Weber, S M Weber, C Wei, Y Wei, A R Weidberg, E J Weik, J Weingarten, M Weirich, C Weiser, C J Wells, T Wenaus, B Wendland, T Wengler, N S Wenke, N Wermes, M Wessels, A M Wharton, A S White, A White, M J White, D Whiteson, L Wickremasinghe, W Wiedenmann, C Wiel, M Wielers, C Wiglesworth, D J Wilbern, H G Wilkens, D M Williams, H H Williams, S Williams, S Willocq, B J Wilson, P J Windischhofer, F I Winkel, F Winklmeier, B T Winter, J K Winter, M Wittgen, M Wobisch, Z Wolffs, J Wollrath, M W Wolter, H Wolters, A F Wongel, S D Worm, B K Wosiek, K W Woźniak, S Wozniewski, K Wraight, C Wu, J Wu, M Wu, M Wu, S L Wu, X Wu, Y Wu, Z Wu, J Wuerzinger, T R Wyatt, B M Wynne, S Xella, L Xia, M Xia, J Xiang, M Xie, X Xie, S Xin, J Xiong, D Xu, H Xu, L Xu, R Xu, T Xu, Y Xu, Z Xu, Z Xu, B Yabsley, S Yacoob, Y Yamaguchi, E Yamashita, H Yamauchi, T Yamazaki, Y Yamazaki, J Yan, S Yan, Z Yan, H J Yang, H T Yang, S Yang, T Yang, X Yang, X Yang, Y Yang, Y Yang, Z Yang, W-M Yao, Y C Yap, H Ye, H Ye, J Ye, S Ye, X Ye, Y Yeh, I Yeletskikh, B K Yeo, M R Yexley, P Yin, K Yorita, S Younas, C J S Young, C Young, Y Yu, M Yuan, R Yuan, L Yue, M Zaazoua, B Zabinski, E Zaid, T Zakareishvili, N Zakharchuk, S Zambito, J A Zamora Saa, J Zang, D Zanzi, O Zaplatilek, C Zeitnitz, H Zeng, J C Zeng, D T Zenger, O Zenin, T Ženiš, S Zenz, S Zerradi, D Zerwas, M Zhai, B Zhang, D F Zhang, J Zhang, J Zhang, K Zhang, L Zhang, P Zhang, R Zhang, S Zhang, T Zhang, X Zhang, X Zhang, Y Zhang, Y Zhang, Z Zhang, Z Zhang, H Zhao, P Zhao, T Zhao, Y Zhao, Z Zhao, A Zhemchugov, J Zheng, K Zheng, X Zheng, Z Zheng, D Zhong, B Zhou, H Zhou, N Zhou, Y Zhou, C G Zhu, J Zhu, Y Zhu, Y Zhu, X Zhuang, K Zhukov, V Zhulanov, N I Zimine, J Zinsser, M Ziolkowski, L Živković, A Zoccoli, K Zoch, T G Zorbas, O Zormpa, W Zou, L Zwalinski
Searches for new resonances are performed using an unsupervised anomaly-detection technique. Events with at least one electron or muon are selected from 140  fb^{-1} of pp collisions at sqrt[s]=13  TeV recorded by ATLAS at the Large Hadron Collider. The approach involves training an autoencoder on data, and subsequently defining anomalous regions based on the reconstruction loss of the decoder. Studies focus on nine invariant mass spectra that contain pairs of objects consisting of one light jet or b jet and either one lepton (e,μ), photon, or second light jet or b jet in the anomalous regions...
February 23, 2024: Physical Review Letters
https://read.qxmd.com/read/38427840/superior-ophthalmic-vein-thrombosis-associated-with-asymptomatic-covid-19-infection
#26
JOURNAL ARTICLE
Bryant A Menke, Christine Ryu, Rao V Chundury
Superior ophthalmic vein thrombosis is a rare condition scarcely described in clinical literature with potentially severe consequences including permanent vision loss. This report details the case of a 70-year-old woman who presented with acute binocular horizontal diplopia, relative proptosis of the OD by 4 mm, and pain OD. On exam, visual acuity was 20/20 OD and 20/30 OS with full extraocular movements. CT revealed proptosis OD with a thrombosed superior ophthalmic varix. Evaluation for etiology of hypercoagulability was unremarkable, although the patient did have an asymptomatic COVID-19 infection 1 month prior...
March 2024: Ophthalmic Plastic and Reconstructive Surgery
https://read.qxmd.com/read/38423552/raising-the-bar-for-disclosure-of-industry-payments-to-doctors
#27
JOURNAL ARTICLE
David B Menkes, Barbara Mintzes, Nikki Macdonald, Joel Lexchin
No abstract text is available yet for this article.
February 29, 2024: BMJ: British Medical Journal
https://read.qxmd.com/read/38413542/the-stress-for-surgeons-exploring-stress-entities-with-the-robotic-senhance-surgical-system
#28
JOURNAL ARTICLE
Vivianda Menke, Olaf Hansen, Johannes Schmidt, Georg Dechantsreiter, Ludger Staib, Mukhammad Davliatov, Florian Schilcher, Bodo Hübner, Francesco Bianco, Zeljko Kastelan, Tomislav Kulis, Tvrtko Hudolin, Luka Penezic, Toni Zekulic, Jerko Andelic, Ilija Juric, Ivan Puda, Raimondas Siaulys, Raimundas Venckus, Marius Jasenus, Vitalijus Eismontas, Narimantas Evaldas Samalavicius
Robotic surgery is on its way to revolutionizing traditional surgical procedures, offering precise and minimally invasive techniques hypothesized to shorten recovery times and improve patient outcomes. While there have been multiple publications on robotic systems' medical and procedural achievements, more emphasis should be put on the surgeon's experience, especially in comparison with laparoscopic surgery. The present report aims to systematically examine the stress impact on surgeons by comparing the robotic Senhance Surgical System (Asensus Surgical, Durham, North Carolina, U...
February 28, 2024: Journal of Robotic Surgery
https://read.qxmd.com/read/38411374/if-you-are-learner-centered-and-you-know-it-raise-your-hand-perspectives-on-and-implementation-of-pedagogical-changes-by-science-instructors-during-the-covid-19-pandemic
#29
JOURNAL ARTICLE
Cristine Donham, Hanbo Hong, Adriana Signorini, Erik Menke, Petra Kranzfelder
Students at Minority-Serving Institutions (MSIs) faced significant hardships while trying to learn through emergency remote teaching (ERT) during the COVID-19 pandemic. Our research aims to investigate if science, technology, engineering, and mathematics (STEM) instructors thought about and enacted more learner-centered teaching practices to alleviate some of this stress encountered by their students. Using semi-structured interviews and classroom observations, we utilized inductive and deductive qualitative research methods to examine two questions: (1) To what extent were STEM instructor's perceived pedagogical changes learner-centered during ERT?; and (2) To what extent were STEM instructor's teaching behaviors and discourse practices learner-centered during ERT? Our findings revealed that during ERT, STEM instructors described using a variety of pedagogical changes that we identified as learner-centered under the Weimer framework, including ideas such as enacting flexible late policies and increased usage of formative assessment...
February 27, 2024: Biochemistry and Molecular Biology Education
https://read.qxmd.com/read/38403981/acute-hepatic-rupture-causing-hemoperitoneum-in-a-dog-with-anaphylaxis
#30
Ashok Padmanabhan, M Ryan Smith, Virginie Wurlod, Jose Cesar Menk Pinto Lima, Fabio Del Piero
A 2-year-old spayed female Siberian Husky was presented with a history of acute onset lethargy, collapse, haematochezia and vomiting. The patient was severely tachycardic and hypotensive. Point-of-care ultrasound revealed gallbladder wall thickening and peritoneal effusion consistent with haemorrhage on subsequent abdominocentesis. Despite attempted medical stabilization over the course of several hours, including blood products and multiple autotransfusions, the patient progressed to cardiopulmonary arrest...
March 2024: Veterinary Medicine and Science
https://read.qxmd.com/read/38400044/an-improved-workflow-for-the-quantification-of-orthohantavirus-infection-using-automated-imaging-and-flow-cytometry
#31
JOURNAL ARTICLE
Laura Menke, Christian Sieben
Determination of the infectious titer is a central requirement when working with pathogenic viruses. The plaque or focus assay is a commonly used but labor- and time-consuming approach for determining the infectious titer of orthohantavirus samples. We have developed an optimized virus quantification approach that relies on the fluorescence-based detection of the orthohantavirus nucleocapsid protein (N) in infected cells with high sensitivity. We present the use of flow cytometry but highlight fluorescence microscopy in combination with automated data analysis as an attractive alternative to increase the information retrieved from an infection experiment...
February 8, 2024: Viruses
https://read.qxmd.com/read/38396455/correlation-between-histopathological-prognostic-tumor-characteristics-and-18-f-fdg-uptake-in-corresponding-metastases-in-newly-diagnosed-metastatic-breast-cancer
#32
JOURNAL ARTICLE
Jorianne Boers, Bertha Eisses, Mieke C Zwager, Jasper J L van Geel, Frederike Bensch, Erik F J de Vries, Geke A P Hospers, Andor W J M Glaudemans, Adrienne H Brouwers, Martijn A M den Dekker, Sjoerd G Elias, Evelien J M Kuip, Carla M L van Herpen, Agnes Jager, Astrid A M van der Veldt, Daniela E Oprea-Lager, Elisabeth G E de Vries, Bert van der Vegt, Willemien C Menke-van der Houven van Oordt, Carolina P Schröder
BACKGROUND: In metastatic breast cancer (MBC), [18 F]fluorodeoxyglucose positron emission tomography/computed tomography ([18 F]FDG-PET/CT) can be used for staging. We evaluated the correlation between BC histopathological characteristics and [18 F]FDG uptake in corresponding metastases. PATIENTS AND METHODS: Patients with non-rapidly progressive MBC of all subtypes prospectively underwent a baseline histological metastasis biopsy and [18 F]FDG-PET. Biopsies were assessed for estrogen, progesterone, and human epidermal growth factor receptor 2 (ER, PR, HER2); Ki-67; and histological subtype...
February 14, 2024: Diagnostics
https://read.qxmd.com/read/38370571/hydroxychloroquine-induced-renal-phospholipidosis-case-report-and-review-of-differential-diagnoses
#33
Amélie Friederike Menke, Barbara Heitplatz, Veerle Van Marck, Hermann Pavenstädt, Ulrich Jehn
INTRODUCTION: Renal phospholipidosis describes the accumulation of phospholipids in the lysosomes of kidney cells, in particular podocytes. Originally, this was described primarily in the context of the lysosomal storage disorder Fabry disease. It is now known that a variety of drugs can lead to the accumulation of lysosomal phospholipids. CASE PRESENTATION: We present the case of a 69-year-old female patient suffering chronic kidney disease and systemic lupus erythematosus who underwent a kidney biopsy because of a further increase in serum creatinine levels...
2024: Case Reports in Nephrology and Dialysis
https://read.qxmd.com/read/38369823/-not-available
#34
JOURNAL ARTICLE
Kanber Kara, Abdullah Altınsoy
BACKGROUND: Forages are widely used in horse diets. Different in vitro techniques are being tried to determine the fermentation levels of forages in the horse digestive tract. OBJECTIVES: This study aimed to evaluate the digestion levels of four dry forages commonly used in horse nutrition: alfalfa herbage, meadow hay, wheat straw, and Italian ryegrass. In vitro total digestion (TDT), in vitro Sunvold-large intestine digestion (SDT) and in vitro Menke-large intestine digestion (MDT) techniques were compared...
March 2024: Veterinary Medicine and Science
https://read.qxmd.com/read/38358425/non-specific-irreversible-89-zr-mab-uptake-in-tumours-evidence-from-biopsy-proven-target-negative-tumours-using-89-zr-immuno-pet
#35
JOURNAL ARTICLE
Jessica E Wijngaarden, Yvonne W S Jauw, Gerben J C Zwezerijnen, Berlinda J de Wit-van der Veen, Daniëlle J Vugts, Josée M Zijlstra, Guus A M S van Dongen, Ronald Boellaard, C Willemien Menke-van der Houven van Oordt, Marc C Huisman
BACKGROUND: Distribution of mAbs into tumour tissue may occur via different processes contributing differently to the 89 Zr-mAb uptake on PET. Target-specific binding in tumours is of main interest; however, non-specific irreversible uptake may also be present, which influences quantification. The aim was to investigate the presence of non-specific irreversible uptake in tumour tissue using Patlak linearization on 89 Zr-immuno-PET data of biopsy-proven target-negative tumours. Data of two studies, including target status obtained from biopsies, were retrospectively analysed, and Patlak linearization provided the net rate of irreversible uptake (Ki )...
February 15, 2024: EJNMMI Research
https://read.qxmd.com/read/38348677/five-year-safety-and-effectiveness-of-paclitaxel-drug-coated-balloons-alone-or-with-provisional-bare-metal-stenting-for-real-world-femoropopliteal-lesions-in-pact-global-study-subgroup-analysis
#36
JOURNAL ARTICLE
Gary M Ansel, Marianne Brodmann, Krishna J Rocha-Singh, Jeremiah S Menk, Thomas Zeller
BACKGROUND: The treatment of complex infra-inguinal disease with drug-coated balloons (DCBs) is associated with a significant number of patients undergoing provisional stenting to treat a suboptimal result. To determine the potential long-term impact of DCB treatment with provisional bare metal stenting in complex lesions in real-world patients, a post hoc analysis was performed on data from the IN.PACT Global Study (The IN.PACT Global Clinical Study for the Treatment of Comprehensive Superficial Femoral and/or Popliteal Artery Lesions Using the IN...
February 13, 2024: Circulation. Cardiovascular Interventions
https://read.qxmd.com/read/38347010/effect-of-nutmeg-essential-oil-myristica-fragrans-houtt-on-methane-production-rumen-fermentation-and-nutrient-digestibility-in-vitro
#37
JOURNAL ARTICLE
Achmad Ezar Abdillah, Dewi Sarah, Aziz Aji Ardian, Muhsin Al Anas, Muhammad Anang Aprianto, Chusnul Hanim, Asih Kurniawati, Muhlisin, Lies Mira Yusiati
The study evaluated the effect of adding of nutmeg (Myristica fragrans Houtt.) essential oil (NEO) as a feed additive on methane production, rumen fermentation parameters, rumen enzyme activity, and nutrient digestibility in vitro. This study was divided into three treatments based on the level of NEO addition, which included 0 µL/L (T0), 100 µL/L (T1), and 200 µL/L (T2). The feed substrate composition consisted of king grass as forage and concentrate in a 60:40 ratio. Feed fermentation was conducted using the Menke and Steingass gas production and two-step Tilley and Terry in-vitro digestibility technique...
February 12, 2024: Scientific Reports
https://read.qxmd.com/read/38339398/cuproptosis-unraveling-the-mechanisms-of-copper-induced-cell-death-and-its-implication-in-cancer-therapy
#38
REVIEW
Chloe Springer, Danish Humayun, Rachid Skouta
Copper, an essential element for various biological processes, demands precise regulation to avert detrimental health effects and potential cell toxicity. This paper explores the mechanisms of copper-induced cell death, known as cuproptosis, and its potential health and disease implications, including cancer therapy. Copper ionophores, such as elesclomol and disulfiram, increase intracellular copper levels. This elevation triggers oxidative stress and subsequent cell death, offering potential implications in cancer therapy...
February 2, 2024: Cancers
https://read.qxmd.com/read/38321232/how-to-obtain-the-image-derived-blood-concentration-from-89-zr-immuno-pet-scans
#39
JOURNAL ARTICLE
Jessica E Wijngaarden, Amina Ahbari, Johanna E E Pouw, Henri N J M Greuter, Idris Bahce, Gerben J C Zwezerijnen, Daniëlle J Vugts, Guus A M S van Dongen, Ronald Boellaard, C Willemien Menke-van der Houven van Oordt, Marc C Huisman
BACKGROUND: PET scans using zirconium-89 labelled monoclonal antibodies (89 Zr-mAbs), known as 89 Zr-immuno-PET, are made to measure uptake in tumour and organ tissue. Uptake is related to the supply of 89 Zr-mAbs in the blood. Measuring activity concentrations in blood, however, requires invasive blood sampling. This study aims to identify the best delineation strategy to obtain the image-derived blood concentration (IDBC) from 89 Zr-immuno-PET scans. METHODS: PET imaging and blood sampling of two 89 Zr-mAbs were included, 89 Zr-cetuximab and 89 Zr-durvalumab...
February 7, 2024: EJNMMI Physics
https://read.qxmd.com/read/38308511/capillary-rarefication-as-a-possible-cause-of-long-covid-syndrome
#40
JOURNAL ARTICLE
Irina Osiaevi, Philipp Kümpers, Julia Weinmann-Menke, Hermann Pavenstädt, Alexandros Rovas
No abstract text is available yet for this article.
February 2, 2024: Nephrology, Dialysis, Transplantation
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