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https://www.readbyqxmd.com/read/27914999/dual-therapy-for-refractory-overactive-bladder-in-children-a-prospective-open-label-study
#1
Fannie Morin, Anne-Sophie Blais, Geneviève Nadeau, Katherine Moore, Lucie Genois, Stéphane Bolduc
PURPOSE: Mirabegron (β3-adrenoreceptor agonist) is a new molecule with a distinct mechanism of action from antimuscarinics. Combination therapy with solifenacin was recently studied in adult population. Our objective was to evaluate the efficacy and safety of mirabegron as add-on therapy, to treat urinary incontinence in children with idiopathic OAB, refractory/intolerant to antimuscarinics. MATERIALS AND METHODS: A prospective off-label study using add-on regimens of mirabegron was conducted with pediatric patients presenting no symptom improvement under intensive behavioural and medical therapies and/or significant side effects (S/E) on antimuscarinic dose escalation...
November 30, 2016: Journal of Urology
https://www.readbyqxmd.com/read/27869766/supporting-teens-with-chronic-pain-to-obtain-high-school-credits-chronic-pain-35-in-alberta
#2
Kathy Reid, Mark Simmonds, Michelle Verrier, Bruce Dick
Chronic pain is a significant problem in children and teens, and adolescents with chronic pain often struggle to attend school on a regular basis. We present in this article a novel program we developed that integrates attendance at a group cognitive-behavioural chronic pain self-management program with earning high school credits. We collaborated with Alberta Education in the development of this course, Chronic Pain 35. Adolescents who choose to enroll are invited to demonstrate their scientific knowledge related to pain, understanding of and engagement with treatment homework, and demonstrate their creativity by completing a project, which demonstrates at least one concept...
November 19, 2016: Children
https://www.readbyqxmd.com/read/27830922/pediatric-selective-mutism-therapy-a-randomized-controlled-trial
#3
Maria Esposito, Francesca Gimigliano, Maria R Barillari, Francesco Precenzano, Maria Ruberto, Joseph Sepe, Umberto Barillari, Raffaele Gimigliano, Roberto Militerni, Giovanni Messina, Marco Carotenuto
BACKGROUND: Selective Mutism (SM) is a rare disease in children coded by DSM-5 as an anxiety disorder. Despite the disabling nature of the disease, there is still no specific treatment. AIMS: The aims of this study were to verify the efficacy of six-month standard psychomotor treatment and the positive changes in lifestyle, in a population of children affected by SM. DESIGN: Randomised Controlled Trial registered in the European Clinical Trials Registry (EuDract 2015-001161-36)...
November 10, 2016: European Journal of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27804857/histopathology-immunohistochemistry-and-molecular-biology-of-follicular-epithelium-derived-pediatric-thyroid-carcinomas
#4
Claudio Spinelli, Paola Collini, Marta Barisella, Angela Greco
Thyroid carcinomas derived from the follicular epithelium are rare in children up to 18 years of age. While the morphological features are superimposable in children and adults, the age at onset is relevant to both the frequency of histotypes and variants, and to their biologic behaviour. Papillary carcinomas (PCs) represent more than 90% of cases. Follicular carcinomas (FCs) rarely occur, and they are mostly represented by minimally invasive (encapsulated) FCs (MIFCs). Poorly differentiated carcinomas (PDCs) are very rare, while anaplastic (undifferentiated) carcinomas are practically nonexistent...
November 1, 2016: Current Pediatric Reviews
https://www.readbyqxmd.com/read/27792401/selection-of-employee-personal-protective-equipment-based-on-aggressive-behavior-in-pediatric-neuropsychiatry
#5
Nancy M Daraiseh, Lauren A Summerville, Li Lin, DaVona Tucker, Adam K Hill, Katherine Salisbury, Michael A Lind
PURPOSE: Hospitalized patients with a developmental or intellectual disability and a psychiatric disorder (dual-diagnosis) often pose a risk to themselves or others leading to high injury rates for their providers. Therefore, evidence-based strategies to reduce employee injuries resulting from interactions are necessary. METHODS: To reduce injuries resulting from interactions with dual-diagnosis patients, the Initial Behavioural Assessment (IBA) and Protective Equipment Decision Key (PEDK) were used in inpatient neuropsychiatry...
October 28, 2016: Developmental Neurorehabilitation
https://www.readbyqxmd.com/read/27777544/qualitative-analysis-of-emergency-department-reports-applied-to-a-pilot-project-for-the-prevention-of-pediatric-burns
#6
E Longo, M Masellis, G Fondi, C Cedri, C Debbia, A Pitidis
Accidents and burns are a major problem in Italy and in industrialized countries, due to the consequences they have on health, especially in children aged 0-4 years. In Italy, about 400 people die each year from burns, with over 70% of these occurring in the home. In the European Union, burns are one of the top five causes of death from accidents, accounting for 3% of all deaths from accidents and violence in those age groups. One percent of all deaths in children are due to burns. In this paper, we illustrate the results of qualitative analysis, conducted according to the methodology of content analysis, on narratives included in the anamnesis of clinical papers at the ED in 738 cases of burns in children (0-14 years) observed in a sample of Emergency Departments in the years 2005-2009...
December 31, 2015: Annals of Burns and Fire Disasters
https://www.readbyqxmd.com/read/27717623/association-between-the-family-nutrition-and-physical-activity-screening-tool-and-obesity-severity-in-youth-referred-to-weight-management
#7
Jared M Tucker, Kathleen Howard, Emily H Guseman, Kimbo E Yee, Heather Saturley, Joey C Eisenmann
BACKGROUND: The Family Nutrition and Physical Activity Screening Tool (FNPA) evaluates family behavioural and environmental factors associated with pediatric obesity, but it is unknown if FNPA scores differ among youth across obesity severities. Our aim was to determine the association between the FNPA and obesity severity in youth referred to weight management. METHODS: Upon initiating treatment, height, weight, and the FNPA were collected according to standard procedures...
October 4, 2016: Obesity Research & Clinical Practice
https://www.readbyqxmd.com/read/27676892/transcultural-adaptation-and-validation-of-the-pediatric-stroke-outcome-measure-summary-of-impressions-psom-soi-into-french
#8
Marie-Doriane Morard, Carole Vuillerot, Mickael Dinomais, Stéphane Chabrier, Mathilde Chevignard, Kim Bull, Eleni Papathanasiou
OBJECTIVE: To translate and validate a French version of the Pediatric Stroke Outcome Measure - summary of impressions (PSOM-SOI), for application in a population of French children after neonatal arterial ischemic stroke (NAIS). The PSOM measures deficiency of body functions and structures. On completion of this examination, the PSOM-SOI was developed containing and scoring 5 subscales: right sensorimotor, left sensorimotor (each with subcategories), language production, language comprehension and cognitive/behavioral...
September 2016: Annals of Physical and Rehabilitation Medicine
https://www.readbyqxmd.com/read/27673503/cortical-morphology-as-a-shared-neurobiological-substrate-of-attention-deficit-hyperactivity-symptoms-and-executive-functioning-a-population-based-pediatric-neuroimaging-study
#9
Sabine E Mous, Tonya White, Ryan L Muetzel, Hanan El Marroun, Jolien Rijlaarsdam, Tinca J C Polderman, Vincent W Jaddoe, Frank C Verhulst, Danielle Posthuma, Henning Tiemeier
BACKGROUND: Attention-deficit/hyperactivity symptoms have repeatedly been associated with poor cognitive functioning. Genetic studies have demonstrated a shared etiology of attention-deficit/hyperactivity disorder (ADHD) and cognitive ability, suggesting a common underlying neurobiology of ADHD and cognition. Further, neuroimaging studies suggest that altered cortical development is related to ADHD. In a large population-based sample we investigated whether cortical morphology, as a potential neurobiological substrate, underlies the association between attention-deficit/hyperactivity symptoms and cognitive problems...
September 23, 2016: Journal of Psychiatry & Neuroscience: JPN
https://www.readbyqxmd.com/read/27645708/psychosocial-health-and-quality-of-life-among-children-with-cardiac-diagnoses-agreement-and-discrepancies-between-parent-and-child-reports
#10
Bhavika J Patel, Lillian Lai, Gary Goldfield, Renee Sananes, Patricia E Longmuir
Psychosocial health issues are common among children with cardiac diagnoses. Understanding parent and child perceptions is important because parents are the primary health information source. Significant discrepancies have been documented between parent/child quality-of-life data but have not been examined among psychosocial diagnostic instruments. This study examined agreement and discrepancies between parent and child reports of psychosocial health and quality of life in the paediatric cardiology population...
September 20, 2016: Cardiology in the Young
https://www.readbyqxmd.com/read/27634166/motor-trajectories-from-birth-to-5-years-of-children-born-at-less-than-30-weeks-gestation-early-predictors-and-functional-implications-protocol-for-a-prospective-cohort-study
#11
Alicia J Spittle, Jennifer L McGinley, Deanne Thompson, Ross Clark, Tara L FitzGerald, Benjamin F Mentiplay, Katherine J Lee, Joy E Olsen, Alice Burnett, Karli Treyvaud, Elisha Josev, Bonnie Alexander, Claire E Kelly, Lex W Doyle, Peter J Anderson, Jeanie Ly Cheong
INTRODUCTION: Motor impairments are one of the most frequently reported adverse neurodevelopmental consequences in children born < 30 weeks' gestation. Up to 15% of children born at < 30 weeks have cerebral palsy and an additional 50% have mild to severe motor impairment at school age. The first 5 years of life are critical for the development of fundamental motor skills. These skills form the basis for more complex skills that are required to competently and confidently participate in schooling, sporting and recreational activities...
October 2016: Journal of Physiotherapy
https://www.readbyqxmd.com/read/27630952/pro-activeness-of-parents-in-accepting-behavior-management-techniques-a-cross-sectional-evaluative-study
#12
Karthik Venkataraghavan, Jolly Shah, Manpreet Kaur, Krishna Trivedi, Shalin Shah, Mira Virda
INTRODUCTION: The contemporary parents are more active and participate in the decision making during dental treatment. AIM: To assess the parents' acceptance towards behavior management techniques commonly used in the pediatric dentistry in different dental situation. MATERIALS AND METHODS: Fifty-one parents participated in the study. Children's dental fear was assessed by the parents before attending power point presentation using Dental Subscale of the Children's Fear Survey Schedule (CFSS-DS)...
July 2016: Journal of Clinical and Diagnostic Research: JCDR
https://www.readbyqxmd.com/read/27612457/characterization-treatment-patterns-and-patient-related-outcomes-of-patients-with-fragile-x-syndrome-in-germany-final-results-of-the-observational-explain-fxs-study
#13
Frank Haessler, Franziska Gaese, Michael Huss, Christoph Kretschmar, Marc Brinkman, Helmut Peters, Samuel Elstner, Michael Colla, David Pittrow
BACKGROUND: As data on the phenotype, characteristics and management of patients with Fragile X Syndrome (FXS) are limited, we aimed to collect such data in Germany in experienced centres involved in the treatment of such patients. METHODS: EXPLAIN-FXS is a prospective observational (non-interventional) study (registry) performed between April 2013 and January 2016 at 18 sites in Germany. Requirements for patient participation included confirmed diagnosis of FXS by genetic testing (>200 CGG repeats) and written informed consent...
September 10, 2016: BMC Psychiatry
https://www.readbyqxmd.com/read/27597399/evaluating-a-smartphone-application-to-improve-child-passenger-safety-and-fire-safety-knowledge-and-behaviour
#14
Elise Omaki, Wendy C Shields, Eileen McDonald, Mary E Aitken, David Bishai, James Case, Andrea Gielen
BACKGROUND: Although proven measures for reducing injury due to motor vehicle collision and residential fires exist, the number of families properly and consistently using child passenger restraints and smoke alarms remains low. This paper describes the design of the Safety In Seconds (SIS) 2.0 study, which aims to evaluate the impact of a smartphone app on parents' use of child restraints and smoke alarms. METHODS: SIS is a multisite randomised controlled trial...
September 5, 2016: Injury Prevention: Journal of the International Society for Child and Adolescent Injury Prevention
https://www.readbyqxmd.com/read/27587003/the-neurobiology-of-social-play-and-its-rewarding-value-in-rats
#15
REVIEW
Louk J M J Vanderschuren, E J Marijke Achterberg, Viviana Trezza
In the young of many mammalian species, including humans, a vigorous and highly rewarding social activity is abundantly expressed, known as social play behaviour. Social play is thought to be important for the development of social, cognitive and emotional processes and their neural underpinnings, and it is disrupted in pediatric psychiatric disorders. Here, we summarize recent progress in our understanding of the brain mechanisms of social play behaviour, with a focus on its rewarding properties. Opioid, endocannabinoid, dopamine and noradrenaline systems play a prominent role in the modulation of social play...
November 2016: Neuroscience and Biobehavioral Reviews
https://www.readbyqxmd.com/read/27544784/predictors-of-treatment-response-to-group-cognitive-behavioural-therapy-for-pediatric-obsessive-compulsive-disorder
#16
Cassie H Lavell, Lara J Farrell, Allison M Waters, Jacinda Cadman
Obsessive-compulsive disorder (OCD) is a debilitating mental health disorder, occurring in 1-2% of children and adolescents. Current evidence-based treatments produce promising rates of remission; however, many children and youth do not fully remit from symptoms. The current study explored predictors of treatment response to a group cognitive-behavioural treatment program for pediatric OCD (N=43). Higher levels of child depression and parental rejection at baseline were found to be associated with higher OCD symptoms at post-treatment...
November 30, 2016: Psychiatry Research
https://www.readbyqxmd.com/read/27465622/hrqol-impact-of-stressful-life-events-in-children-beginning-primary-school-results-of-a-prospective-study-in-poland
#17
Maria Kaczmarek, Sylwia Trambacz-Oleszak
PURPOSE: To evaluate the relationship between recent stressful life events (SLEs), stress-related symptoms (SRSs), and health-related quality of life (HRQoL) in children beginning primary school. METHODS: A community-based sample of 6- to 8-year-old children (176 boys and 175 girls at baseline) participated in a prospective longitudinal study with three waves of data collection and 1-year interval between subsequent surveys, conducted in the Wielkopolska Province, Poland...
July 27, 2016: Quality of Life Research
https://www.readbyqxmd.com/read/27461191/analgesia-for-acute-gingivostomatitis-a-national-survey-of-pediatric-emergency-physicians
#18
Joe MacLellan, Samina Ali, Sarah Curtis, Jason Baserman, Andrew Dixon
OBJECTIVES: Gingivostomatitis is a common, painful pediatric presentation, and yet, few studies are available to guide management. We aimed to describe pediatric emergency physicians' current practice patterns, with respect to analgesic use in children with acute gingivostomatitis, in order to inform future studies. METHODS: A national survey was conducted at all 15 national academic pediatric centres. Electronic surveys were distributed to pediatric emergency physicians using a modified Dillman protocol; non-respondents received paper surveys via post...
July 27, 2016: CJEM
https://www.readbyqxmd.com/read/27395805/brief-intensive-cbt-for-pediatric-ocd-with-e-therapy-maintenance
#19
Lara J Farrell, Ella L Oar, Allison M Waters, Harry McConnell, Evelin Tiralongo, Vinay Garbharran, Thomas Ollendick
Cognitive behaviour therapy (CBT), incorporating exposure and response prevention (ERP), has received strong empirical support for the treatment of paediatric OCD, and moreover, is considered the first line treatment of choice (Geller & March, 2012). However, despite the availability of effective treatments for this chronic and debilitating disorder, only a small proportion of youth receive these evidence-based approaches. The present study aimed to examine the effectiveness of an intensive ERP-based treatment for youth OCD, using a multiple baseline controlled design...
August 2016: Journal of Anxiety Disorders
https://www.readbyqxmd.com/read/27365176/paternal-age-and-diet-the-contributions-of-a-father-s-experience-to-susceptibility-for-post-concussion-symptomology
#20
Harleen Hehar, Katrina Yu, Irene Ma, Richelle Mychasiuk
In an attempt to improve current understanding of risk factors that influence individual susceptibility to poor outcomes following mild traumatic brain injury (mTBI) or concussion, this project investigated whether modifications to paternal experiences (Advanced Age (AA) or High-Fat Diet (HFD)) affected offspring susceptibility to behavioral symptomology and changes in gene expression following pediatric concussion in a rodent model. The study demonstrated that paternal treatment prior to conception altered behavioral outcomes and molecular characterization of offspring...
September 22, 2016: Neuroscience
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