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MULTICENTER STUDY
John P Bigouette, Erin C Owen, Brett Brick A Lantz, Rudolf G Hoellrich, Rick W Wright, Laura J Huston, Amanda K Haas, Christina R Allen, Daniel E Cooper, Thomas M DeBerardino, Warren R Dunn, Kurt P Spindler, Michael J Stuart, John P Albright, Annunziato Ned Amendola, Christopher C Annunziata, Robert A Arciero, Bernard R Bach, Champ L Baker, Arthur R Bartolozzi, Keith M Baumgarten, Jeffery R Bechler, Jeffrey H Berg, Geoffrey A Bernas, Stephen F Brockmeier, Robert H Brophy, Charles A Bush-Joseph, J Brad Butler V, James L Carey, James E Carpenter, Brian J Cole, Jonathan M Cooper, Charles L Cox, R Alexander Creighton, Tal S David, David C Flanigan, Robert W Frederick, Theodore J Ganley, Elizabeth A Garofoli, Charles J Gatt, Steven R Gecha, James Robert Giffin, Sharon L Hame, Jo A Hannafin, Christopher D Harner, Norman Lindsay Harris, Keith S Hechtman, Elliott B Hershman, David C Johnson, Timothy S Johnson, Morgan H Jones, Christopher C Kaeding, Ganesh V Kamath, Thomas E Klootwyk, Bruce A Levy, C Benjamin Ma, G Peter Maiers, Robert G Marx, Matthew J Matava, Gregory M Mathien, David R McAllister, Eric C McCarty, Robert G McCormack, Bruce S Miller, Carl W Nissen, Daniel F O'Neill, Brett D Owens, Richard D Parker, Mark L Purnell, Arun J Ramappa, Michael A Rauh, Arthur C Rettig, Jon K Sekiya, Kevin G Shea, Orrin H Sherman, James R Slauterbeck, Matthew V Smith, Jeffrey T Spang, Ltc Steven J Svoboda, Timothy N Taft, Joachim J Tenuta, Edwin M Tingstad, Armando F Vidal, Darius G Viskontas, Richard A White, James S Williams, Michelle L Wolcott, Brian R Wolf, James J York
BACKGROUND: Patients with anterior cruciate ligament (ACL) revision report lower outcome scores on validated knee questionnaires postoperatively compared to cohorts with primary ACL reconstruction. In a previously active population, it is unclear if patient-reported outcomes (PROs) are associated with a return to activity (RTA) or vary by sports participation level (higher level vs. recreational athletes). HYPOTHESES: Individual RTA would be associated with improved outcomes (ie, decreased knee symptoms, pain, function) as measured using validated PROs...
June 2022: American Journal of Sports Medicine
#22
RANDOMIZED CONTROLLED TRIAL
The impact of perioperative stroke and delirium on outcomes after surgical aortic valve replacement.
Steven R Messé, Jessica R Overbey, Vinod H Thourani, Alan J Moskowitz, Annetine C Gelijns, Mark A Groh, Michael J Mack, Gorav Ailawadi, Karen L Furie, Andrew M Southerland, Michael L James, Claudia Scala Moy, Lopa Gupta, Pierre Voisine, Louis P Perrault, Michael E Bowdish, A Marc Gillinov, Patrick T O'Gara, Maral Ouzounian, Bryan A Whitson, John C Mullen, Marissa A Miller, James S Gammie, Stephanie Pan, Guray Erus, Jeffrey N Browndyke
OBJECTIVE: The effects of stroke and delirium on postdischarge cognition and patient-centered health outcomes after surgical aortic valve replacement (SAVR) are not well characterized. Here, we assess the impact of postoperative stroke and delirium on these health outcomes in SAVR patients at 90 days. METHODS: Patients (N = 383) undergoing SAVR (41% received concomitant coronary artery bypass graft) enrolled in a randomized trial of embolic protection devices underwent serial neurologic and delirium evaluations at postoperative days 1, 3, and 7 and magnetic resonance imaging at day 7...
February 2024: Journal of Thoracic and Cardiovascular Surgery
#23
JOURNAL ARTICLE
Daniel L Drane, Jon T Willie, Nigel P Pedersen, Deqiang Qiu, Natalie L Voets, Scott R Millis, Bruno P Soares, Amit M Saindane, Ranliang Hu, Michelle S Kim, Kelsey C Hewitt, Shahin Hakimian, Thomas Grabowski, Jeffrey G Ojemann, David W Loring, Kimford J Meador, Edward Faught, John W Miller, Robert E Gross
Objective: To evaluate declarative memory outcomes in medically refractory epilepsy patients who underwent either a highly selective laser ablation of the amygdalohippocampal complex or a conventional open temporal lobe resection. Methods: Post-operative change scores were examined for verbal memory outcome in epilepsy patients who underwent stereotactic laser amygdalohippocampotomy (SLAH: n = 40) or open resection procedures ( n = 40) using both reliable change index (RCI) scores and a 1-SD change metric. Results: Using RCI scores, patients undergoing open resection (12/40, 30...
2021: Frontiers in Neurology
#24
JOURNAL ARTICLE
Dongxia Ge, Michael J O'Brien, Felix H Savoie, Jeffrey M Gimble, Xiying Wu, Margaret H Gilbert, Gabrielle L Clark-Patterson, Jason D Schuster, Kristin S Miller, Alun Wang, Leann Myers, Zongbing You
Localized cartilage lesions in early osteoarthritis and acute joint injuries are usually treated surgically to restore function and relieve pain. However, a persistent clinical challenge remains in how to repair the cartilage lesions. We expressed doublecortin (DCX) in human adipose-derived stromal/stem cells (hASCs) and engineered hASCs into cartilage tissues using an in vitro 96-well pellet culture system. The cartilage tissue constructs with and without DCX expression were implanted in the knee cartilage defects of rabbits (n = 42) and monkeys (n = 12)...
November 30, 2021: NPJ Regenerative Medicine
#25
JOURNAL ARTICLE
Andrew L Ko, Ai Phuong S Tong, Mahmud Mossa-Basha, Kurt E Weaver, Jeffrey G Ojemann, John W Miller, Shahin Hakimian
OBJECTIVE: Laser interstitial thermal therapy (LITT) is a minimally invasive surgery for mesial temporal lobe epilepsy (mTLE), but the effects of individual patient anatomy and location of ablation volumes affect seizure outcomes. The purpose of this study is to see if features of individual patient structural connectomes predict surgical outcomes after LITT for mTLE. METHODS: This is a retrospective analysis of seizure outcomes of LITT for mTLE in 24 patients. We use preoperative diffusion tensor imaging (DTI) to simulate changes in structural connectivity after laser ablation...
November 24, 2021: Epilepsia
#26
JOURNAL ARTICLE
Katherine A Hrebinko, Jason L Sperry, Francis X Guyette, Joshua B Brown, Brian J Daley, Richard S Miller, Brian G Harbrecht, Jeffrey A Claridge, Herb A Phelan, Matthew D Neal, Brian S Zuckerbraun, Mark H Yazer, Kristina J Nicholson
Importance: Prehospital plasma transfusion is lifesaving for trauma patients in hemorrhagic shock but is not commonly used owing to cost and feasibility concerns. Objective: To evaluate the cost-effectiveness of prehospital thawed plasma transfusion in trauma patients with hemorrhagic shock during air medical transport. Design, Setting, and Participants: A decision tree and Markov model were created to compare standard care and prehospital thawed plasma transfusion using published and unpublished patient-level data from the Prehospital Plasma in Air Medical Transport in Trauma Patients at Risk for Hemorrhagic Shock (PAMPer) trial conducted from May 2014 to October 2017, health care and trauma-specific databases, and the published literature...
December 1, 2021: JAMA Surgery
#27
JOURNAL ARTICLE
Husayn A Ladhani, Vanessa P Ho, C Clare Charbonnet, Jason L Sperry, Francis X Guyette, Joshua B Brown, Brian J Daley, Richard S Miller, Brian G Harbrecht, Herb A Phelan, Jeffrey A Claridge
BACKGROUND: The Prehospital Air Medical Plasma (PAMPer) trial demonstrated a survival benefit to trauma patients who received thawed plasma as part of early resuscitation. The objective of our study was to examine the association between blood transfusion and nosocomial infections among trauma patients who participated in the PAMPer trial. We hypothesized that transfusion of blood products will be associated with the development of nosocomial infections in a dose-dependent fashion. METHODS: We performed a secondary analysis of prospectively collected data of patients in the PAMPer trial with hospital length of stay of at least 3 days...
August 1, 2021: Journal of Trauma and Acute Care Surgery
#28
JOURNAL ARTICLE
Kevin C Miller, John P Marinelli, Jeffrey R Janus, Ashish V Chintakuntlawar, Robert L Foote, Michael J Link, Garret Choby, Jamie J Van Gompel
Esthesioneuroblastoma (ENB) is a rare olfactory malignancy that can present with locally advanced disease. At our institution, patients with ENB in whom the treating surgeon believes that a margin-negative resection is initially not achievable are selected to undergo induction with chemotherapy with or without radiotherapy prior to surgery. In a retrospective review of 61 patient records, we identified six patients (10%) treated with this approach. Five of six patients (83%) went on to definitive surgery. Prior to surgery, three of five patients (60%) had a partial response after induction therapy, whereas two of five (40%) had stable disease...
July 2021: Journal of Neurological Surgery. Part B, Skull Base
#29
JOURNAL ARTICLE
Rick W Wright, Laura J Huston, Amanda K Haas, Jacquelyn S Pennings, Christina R Allen, Daniel E Cooper, Thomas M DeBerardino, Warren R Dunn, Brett Brick A Lantz, Kurt P Spindler, Michael J Stuart, John P Albright, Annunziato Ned Amendola, Jack T Andrish, Christopher C Annunziata, Robert A Arciero, Bernard R Bach, Champ L Baker, Arthur R Bartolozzi, Keith M Baumgarten, Jeffery R Bechler, Jeffrey H Berg, Geoffrey A Bernas, Stephen F Brockmeier, Robert H Brophy, Charles A Bush-Joseph, J Brad Butler V, John D Campbell, James L Carey, James E Carpenter, Brian J Cole, Jonathan M Cooper, Charles L Cox, R Alexander Creighton, Diane L Dahm, Tal S David, David C Flanigan, Robert W Frederick, Theodore J Ganley, Elizabeth A Garofoli, Charles J Gatt, Steven R Gecha, James Robert Giffin, Sharon L Hame, Jo A Hannafin, Christopher D Harner, Norman Lindsay Harris, Keith S Hechtman, Elliott B Hershman, Rudolf G Hoellrich, David C Johnson, Timothy S Johnson, Morgan H Jones, Christopher C Kaeding, Ganesh V Kamath, Thomas E Klootwyk, Bruce A Levy, C Benjamin Ma, G Peter Maiers, Robert G Marx, Matthew J Matava, Gregory M Mathien, David R McAllister, Eric C McCarty, Robert G McCormack, Bruce S Miller, Carl W Nissen, Daniel F O'Neill, Brett D Owens, Richard D Parker, Mark L Purnell, Arun J Ramappa, Michael A Rauh, Arthur C Rettig, Jon K Sekiya, Kevin G Shea, Orrin H Sherman, James R Slauterbeck, Matthew V Smith, Jeffrey T Spang, Ltc Steven J Svoboda, Timothy N Taft, Joachim J Tenuta, Edwin M Tingstad, Armando F Vidal, Darius G Viskontas, Richard A White, James S Williams, Michelle L Wolcott, Brian R Wolf, James J York
BACKGROUND: Although graft choice may be limited in the revision setting based on previously used grafts, most surgeons believe that graft choice for anterior cruciate ligament (ACL) reconstruction is an important factor related to outcome. HYPOTHESIS: In the ACL revision setting, there would be no difference between autograft and allograft in rerupture rate and patient-reported outcomes (PROs) at 6-year follow-up. STUDY DESIGN: Cohort study; Level of evidence, 2...
August 2021: American Journal of Sports Medicine
#30
MULTICENTER STUDY
Stephen P Canton, Waseem Lutfi, Brian J Daley, Richard S Miller, Brian G Harbrecht, Jeffrey A Claridge, Herb A Phelan, Francis X Guyette, Jason L Sperry, Joshua B Brown
BACKGROUND: Prehospital plasma transfusion in trauma reduces mortality. However, the underlying mechanism remains unclear. Reduction in shock severity may play a role. Lactate correlates with physiologic shock severity and mortality after injury. Our objective was to determine if prehospital plasma reduces lactate and if this contributes to the mortality benefit of plasma. METHODS: Patients in the Prehospital Air Medical Plasma trial in the upper quartile of injury severity (Injury Severity Score, >30) were included to capture severe shock...
July 1, 2021: Journal of Trauma and Acute Care Surgery
#31
JOURNAL ARTICLE
Jeffrey S Miller, Krithika Ramaprabhu, Eltayeb Mohamed Ahmed, Michael E Halkos, Douglas A Murphy
A 54-year-old woman with end-stage renal disease on hemodialysis with access through a right arm arteriovenous fistula presented with right arm swelling. Venography demonstrated right subclavian vein stenosis. A balloon angioplasty of the stenotic vein was unsuccessful, and she subsequently underwent stent placement with balloon angioplasty. Ten days following the procedure, she developed acute shortness of breath. Transthoracic echocardiogram demonstrated the migration of the venous stent into the right ventricle...
March 23, 2021: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
#32
JOURNAL ARTICLE
Katherine M Reitz, Danielle S Gruen, Frances Guyette, Joshua B Brown, Mark H Yazer, Yoram Vodovotz, Pär I Johanssen, Jakob Stensballe, Brian Daley, Richard S Miller, Brian G Harbrecht, Jeffrey Claridge, Herb A Phelan, Matthew D Neal, Brian S Zuckerbraun, Jason L Sperry
Background: Prehospital plasma administration during air medical transport reduces the endotheliopathy of trauma, circulating pro-inflammatory cytokines, and 30-day mortality among traumatically injured patients at risk of hemorrhagic shock. No clinical data currently exists evaluating the age of thawed plasma and its association with clinical outcomes and biomarker expression post-injury. Methods: We performed a secondary analysis from the prehospital plasma administration randomized controlled trial, PAMPer...
2021: Trauma Surgery & Acute Care Open
#33
JOURNAL ARTICLE
Robert H Brophy, Rick W Wright, Laura J Huston, Amanda K Haas, Samuel K Nwosu, Christina R Allen, Allen F Anderson, Daniel E Cooper, Thomas M DeBerardino, Warren R Dunn, Brett Brick A Lantz, Barton Mann, Kurt P Spindler, Michael J Stuart, Jacquelyn S Pennings, John P Albright, Annunziato Ned Amendola, Jack T Andrish, Christopher C Annunziata, Robert A Arciero, Bernard R Bach, Champ L Baker, Arthur R Bartolozzi, Keith M Baumgarten, Jeffery R Bechler, Jeffrey H Berg, Geoffrey A Bernas, Stephen F Brockmeier, Charles A Bush-Joseph, J Brad Butler, John D Campbell, James L Carey, James E Carpenter, Brian J Cole, Jonathan M Cooper, Charles L Cox, R Alexander Creighton, Diane L Dahm, Tal S David, David C Flanigan, Robert W Frederick, Theodore J Ganley, Elizabeth A Garofoli, Charles J Gatt, Steven R Gecha, James Robert Giffin, Sharon L Hame, Jo A Hannafin, Christopher D Harner, Norman Lindsay Harris, Keith S Hechtman, Elliott B Hershman, Rudolf G Hoellrich, Timothy M Hosea, David C Johnson, Timothy S Johnson, Morgan H Jones, Christopher C Kaeding, Ganesh V Kamath, Thomas E Klootwyk, Bruce A Levy, C Benjamin Ma, G Peter Maiers, Robert G Marx, Matthew J Matava, Gregory M Mathien, David R McAllister, Eric C McCarty, Robert G McCormack, Bruce S Miller, Carl W Nissen, Daniel F O'Neill, Brett D Owens, Richard D Parker, Mark L Purnell, Arun J Ramappa, Michael A Rauh, Arthur C Rettig, Jon K Sekiya, Kevin G Shea, Orrin H Sherman, James R Slauterbeck, Matthew V Smith, Jeffrey T Spang, Ltc Steven J Svoboda, Timothy N Taft, Joachim J Tenuta, Edwin M Tingstad, Armando F Vidal, Darius G Viskontas, Richard A White, James S Williams, Michelle L Wolcott, Brian R Wolf, James J York
Infection is a rare occurrence after revision anterior cruciate ligament reconstruction (rACLR). Because of the low rates of infection, it has been difficult to identify risk factors for infection in this patient population. The purpose of this study was to report the rate of infection following rACLR and assess whether infection is associated with patient- and surgeon- dependent risk factors. We reviewed two large prospective cohorts to identify patients with postoperative infections following rACLR. Age, sex, body mass index (BMI), smoking status, history of diabetes, and graft choice were recorded for each patient...
October 1, 2020: Journal of Orthopaedic Research: Official Publication of the Orthopaedic Research Society
#34
MULTICENTER STUDY
Rick W Wright, Laura J Huston, Amanda K Haas, Samuel K Nwosu, Christina R Allen, Allen F Anderson, Daniel E Cooper, Thomas M DeBerardino, Warren R Dunn, Brett Brick A Lantz, Barton Mann, Kurt P Spindler, Michael J Stuart, Jacquelyn S Pennings, John P Albright, Annunziato Ned Amendola, Jack T Andrish, Christopher C Annunziata, Robert A Arciero, Bernard R Bach, Champ L Baker, Arthur R Bartolozzi, Keith M Baumgarten, Jeffery R Bechler, Jeffrey H Berg, Geoffrey A Bernas, Stephen F Brockmeier, Robert H Brophy, Charles A Bush-Joseph, J Brad Butler V, John D Campbell, James L Carey, James E Carpenter, Brian J Cole, Jonathan M Cooper, Charles L Cox, R Alexander Creighton, Diane L Dahm, Tal S David, David C Flanigan, Robert W Frederick, Theodore J Ganley, Elizabeth A Garofoli, Charles J Gatt, Steven R Gecha, James Robert Giffin, Sharon L Hame, Jo A Hannafin, Christopher D Harner, Norman Lindsay Harris, Keith S Hechtman, Elliott B Hershman, Rudolf G Hoellrich, Timothy M Hosea, David C Johnson, Timothy S Johnson, Morgan H Jones, Christopher C Kaeding, Ganesh V Kamath, Thomas E Klootwyk, Bruce A Levy, C Benjamin Ma, G Peter Maiers, Robert G Marx, Matthew J Matava, Gregory M Mathien, David R McAllister, Eric C McCarty, Robert G McCormack, Bruce S Miller, Carl W Nissen, Daniel F O'Neill, Brett D Owens, Richard D Parker, Mark L Purnell, Arun J Ramappa, Michael A Rauh, Arthur C Rettig, Jon K Sekiya, Kevin G Shea, Orrin H Sherman, James R Slauterbeck, Matthew V Smith, Jeffrey T Spang, Ltc Steven J Svoboda, Timothy N Taft, Joachim J Tenuta, Edwin M Tingstad, Armando F Vidal, Darius G Viskontas, Richard A White, James S Williams, Michelle L Wolcott, Brian R Wolf, James J York
BACKGROUND: Meniscal preservation has been demonstrated to contribute to long-term knee health. This has been a successful intervention in patients with isolated tears and tears associated with anterior cruciate ligament (ACL) reconstruction. However, the results of meniscal repair in the setting of revision ACL reconstruction have not been documented. PURPOSE: To examine the prevalence and 2-year operative success rate of meniscal repairs in the revision ACL setting...
October 2020: American Journal of Sports Medicine
#35
JOURNAL ARTICLE
Joshua A Boys, Beina Azadgoli, Mathew Martinez, Daniel S Oh, Jeffrey A Hagen, Steven R DeMeester
INTRODUCTION: Esophagogastroduodenoscopy (EGD) is commonly performed in patients with gastroesophageal reflux disease (GERD). An EGD report should document pertinent findings such as esophagitis, a columnar-lined esophagus (CLE), the location of the squamo-columnar and gastroesophageal junctions, the size and type of a hiatal hernia and the number and location of any biopsies. The aim of this study was to evaluate how commonly these findings were noted in the EGD reports of patients referred for antireflux surgery...
June 30, 2020: Journal of Gastrointestinal Surgery
#36
JOURNAL ARTICLE
John M Fallon, Noah Newman, Parth M Patel, William Keeling, Tamer Attia, Jeffrey S Miller, Wissam Jaber, Yazan Duwayri, Kaustubh Wagh, Omar Lattouf
PURPOSE: Despite paucity of data, there exists growing popularity of catheter-based extraction methods for intravascular thrombi and vegetations. We describe a large single center experience with vacuum-assisted extraction techniques (VAET) for right-sided intravascular and cardiac masses. METHODS: We retrospectively reviewed the perioperative course of patients undergoing VAET between 2014 and 2019. Primary outcomes were survival and freedom from recurrent bacteremia...
June 19, 2020: Journal of Cardiac Surgery
#37
JOURNAL ARTICLE
David Zapata, Jose Binongo, Yi Lasanajak, Jane Wei, Bradley G Leshnower, Edward P Chen, Jeffrey S Miller, Omar M Lattouf, Robert A Guyton, Michael E Halkos, Brent Keeling
OBJECTIVE: The incidence and outcomes of patients with heparin-induced thrombocytopenia (HIT) are well defined for general cardiac surgical populations. The purpose of this study was to define the outcomes of patients with HIT in a population excluding patients who underwent coronary artery bypass grafting (CABG). METHODS: The local Society of Thoracic Surgeons cardiac surgical database was queried between January 2008 and May 2017 for patients who underwent either open valvular surgery or aortic surgery...
March 26, 2020: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
#38
JOURNAL ARTICLE
Andge Valiakhmetova, Sergey Gorelyshev, Alexander Konovalov, Yuri Trunin, Alexander Savateev, David E Kram, Eric Severson, Amanda Hemmerich, Claire Edgerly, Daniel Duncan, Nicholas Britt, Richard S P Huang, Julia Elvin, Vincent Miller, Jeffrey S Ross, Laurie Gay, Joshua McCorkle, Andrew Rankin, Rachel L Erlich, Yakov Chudnovsky, Shakti H Ramkissoon
For pediatric patients with high-grade gliomas, standard-of-care treatment includes surgery, chemotherapy, and radiation therapy; however, most patients ultimately succumb to their disease. With advances in genomic characterization of pediatric high-grade gliomas, the use of targeted therapies in combination with current treatment modalities offer the potential to improve survival in this patient population. In this report, we present the case of a 3-year-old girl with glioblastoma who continues to experience an exceptional and durable response (>2 years) to the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib...
February 2020: Oncologist
#39
REVIEW
Andge Valiakhmetova, Sergey Gorelyshev, Alexander Konovalov, Yuri Trunin, Alexander Savateev, David E Kram, Eric Severson, Amanda Hemmerich, Claire Edgerly, Daniel Duncan, Nicholas Britt, Richard S P Huang, Julia Elvin, Vincent Miller, Jeffrey S Ross, Laurie Gay, Joshua McCorkle, Andrew Rankin, Rachel L Erlich, Yakov Chudnovsky, Shakti H Ramkissoon
For pediatric patients with high-grade gliomas, standard-of-care treatment includes surgery, chemotherapy, and radiation therapy; however, most patients ultimately succumb to their disease. With advances in genomic characterization of pediatric high-grade gliomas, the use of targeted therapies in combination with current treatment modalities offer the potential to improve survival in this patient population. In this report, we present the case of a 3-year-old girl with glioblastoma who continues to experience an exceptional and durable response (>2 years) to the poly (ADP-ribose) polymerase (PARP) inhibitor olaparib...
October 16, 2019: Oncologist
#40
JOURNAL ARTICLE
Al B Benson, Alan P Venook, Mahmoud M Al-Hawary, Mustafa A Arain, Yi-Jen Chen, Kristen K Ciombor, Stacey A Cohen, Harry S Cooper, Dustin A Deming, Ignacio Garrido-Laguna, Jean L Grem, Sarah E Hoffe, Joleen Hubbard, Steven Hunt, Ahmed Kamel, Natalie Kirilcuk, Smitha Krishnamurthi, Wells A Messersmith, Jeffrey Meyerhardt, Eric D Miller, Mary F Mulcahy, Steven Nurkin, Michael J Overman, Aparna Parikh, Hitendra Patel, Katrina S Pedersen, Leonard B Saltz, Charles Schneider, David Shibata, John M Skibber, Constantinos T Sofocleous, Elena M Stoffel, Eden Stotsky-Himelfarb, Christopher G Willett, Alyse Johnson-Chilla, Kristina M Gregory, Lisa A Gurski
Small bowel adenocarcinoma (SBA) is a rare malignancy of the gastrointestinal tract that has increased in incidence across recent years. Often diagnosed at an advanced stage, outcomes for SBA are worse on average than for other related malignancies, including colorectal cancer. Due to the rarity of this disease, few studies have been done to direct optimal treatment, although recent data have shown that SBA responds to treatment differently than colorectal cancer, necessitating a separate approach to treatment...
September 1, 2019: Journal of the National Comprehensive Cancer Network: JNCCN
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