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https://www.readbyqxmd.com/read/28516158/a-management-algorithm-for-mitomycin-c-induced-cystitis
#1
Amy N Luckenbaugh, Rory M Marks, David C Miller, Alon Z Weizer, John T Stoffel, Jeffrey S Montgomery
Background/Objective: A post-bladder tumor resection dose of MMC can reduce non-invasive papillary (pTa) bladder cancer recurrences by up to 40%; this treatment is recommended in both the AUA and EUA non-muscle-invasive bladder cancer guidelines. A common complication of this treatment is eosinophilic cystitis. Symptoms range from mild urinary frequency and urgency to debilitating pain and dysuria. Currently, there is no established treatment algorithm for MMC-induced cystitis. Methods: Members of the Urologic Surgery Quality Collaborative (USQC), a group composed of over 160 private and academic urologists, met to discuss the management of patients with cystitis following MMC therapy...
April 27, 2017: Bladder Cancer
https://www.readbyqxmd.com/read/28495236/fireworks-type-injury-pattern-and-permanent-impairment-following-severe-fireworks-related-injuries
#2
Brinkley K Sandvall, Lauren Jacobson, Erin A Miller, Ryan E Dodge, D Alex Quistberg, Ali Rowhani-Rahbar, Monica S Vavilala, Jeffrey B Friedrich, Kari A Keys
BACKGROUND: There is a paucity of clinical data on severe fireworks-related injuries, and the relationship between firework types, injury patterns, and magnitude of impairment is not well understood. Our objective was to describe the relationship between fireworks type, injury patterns, and impairment. METHODS: Retrospective case series (2005-2015) of patients who sustained consumer fireworks-related injuries requiring hospital admission and/or an operation at a Level 1 Trauma/Burn Center...
April 25, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28392393/functional-outcomes-following-nerve-sparing-prostatectomy-augmented-with-seminal-vesicle-sparing-compared-to-standard-nerve-sparing-prostatectomy-results-from-a-randomized-controlled-trial
#3
Scott M Gilbert, Rodney L Dunn, David C Miller, Jeffrey S Montgomery, Ted A Skolarus, Alon Z Weizer, David P Wood, Brent K Hollenbeck
INTRODUCTION: Seminal vesicle sparing may reduce the risk of neurovascular bundle injury and improve functional outcomes after prostatectomy. While several observational studies have reported better functional outcomes following seminal vesicle sparing approaches, evidence from randomized trials is lacking. We conducted a randomized controlled trial comparing functional and cancer control outcomes between nerve-sparing prostatectomy augmented with seminal vesicle sparing (NSP+SVS) and standard nerve-sparing prostatectomy (NSP)...
April 6, 2017: Journal of Urology
https://www.readbyqxmd.com/read/28180037/complications-of-open-approaches-to-the-skull-base-in-the-endoscopic-era
#4
Justin D Miller, Robert J Taylor, Emily C Ambrose, Jeffrey P Laux, Charles S Ebert, Adam M Zanation
Objective It is important to characterize the developing complication profile of the open approach as it becomes reserved for more complex disease during the endoscopic era. Our objective was to characterize complication rates of current open skull base surgery. Design Retrospective chart review. Setting Tertiary care center. Participants The study group consisted of 103 patients and 117 open skull base surgeries were performed from 2008 to 2012. Main Outcome Measures Intraoperative/postoperative complications...
February 2017: Journal of Neurological Surgery. Part B, Skull Base
https://www.readbyqxmd.com/read/28139024/anatomical-patterns-of-recurrence-following-biochemical-relapse-after-post-prostatectomy-salvage-radiation-therapy-a-multi-institutional-study
#5
William C Jackson, Neil B Desai, Ahmed E Abugharib, Vasu Tumati, Robert T Dess, Jae Y Lee, Shuang G Zhao, Moaaz Soliman, Michael Folkert, Aaron Laine, Raquibul Hannan, Zachary S Zumsteg, Howard Sandler, Daniel A Hamstra, Jeffrey S Montgomery, David C Miller, Mike A Kozminski, Brent K Hollenbeck, Jason W Hearn, Ganesh Palapattu, Scott A Tomlins, Rohit Mehra, Todd M Morgan, Felix Y Feng, Daniel E Spratt
OBJECTIVES: To characterise the frequency and detailed anatomical sites of failure for patients receiving post-radical prostatectomy (RP) salvage radiation therapy (SRT). PATIENTS AND METHODS: A multi-institutional retrospective study was performed on 574 men who underwent SRT between 1986 and 2013. Anatomical recurrence patterns were classified as lymphotrophic (lymph nodes only), osteotrophic (bone only), or multifocal if both were present. Isolated first failure sites were defined as sites of initial clinically detected recurrence that remained isolated for at least 3 months...
January 31, 2017: BJU International
https://www.readbyqxmd.com/read/27913152/development-and-validation-of-an-objective-scoring-tool-for-robot-assisted-radical-prostatectomy-prostatectomy-assessment-and-competency-evaluation
#6
Ahmed A Hussein, Khurshid R Ghani, James Peabody, Richard Sarle, Ronney Abaza, Daniel Eun, Jim Hu, Michael Fumo, Brian Lane, Jeffrey S Montgomery, Nobuyuki Hinata, Deborah Rooney, Bryan Comstock, Hei Kit Chan, Sridhar S Mane, James L Mohler, Gregory Wilding, David Miller, Khurshid A Guru
PURPOSE: Comprehensive training and skill acquisition by urological surgeons are vital to optimize surgical outcomes and patient safety. We sought to develop and validate PACE (Prostatectomy Assessment and Competence Evaluation), an objective and procedure specific tool to assess the quality of robot-assisted radical prostatectomy. MATERIALS AND METHODS: Development and content validation of PACE was performed by deconstructing robot-assisted radical prostatectomy into 7 key domains utilizing the Delphi methodology...
May 2017: Journal of Urology
https://www.readbyqxmd.com/read/27755204/distinguishing-pseudomeningocele-epidural-hematoma-and-postoperative-infection-on-postoperative-mri
#7
Kris Radcliff, William B Morrison, Christopher Kepler, Jeffrey Moore, Gursukhman S Sidhu, David Gendelberg, Luciano Miller, Marcos A Sonagli, Alexander R Vaccaro
STUDY DESIGN: Retrospective case series. OBJECTIVE: To identify specific magnetic resonance imaging (MRI) characteristics of epidural fluid collections associated with infection, hematoma, or cerebrospinal fluid (CSF). SUMMARY OF BACKGROUND DATA: Interpretation of postoperative MRI can be challenging after lumbar fusion. The purpose of this study was to identify specific MRI characteristics of epidural fluid collections associated with infection, hematoma, or CSF...
November 2016: Clinical Spine Surgery
https://www.readbyqxmd.com/read/27717426/the-racial-paradox-in-multiarterial-conduit-utilization-for-coronary-artery-bypass-grafting
#8
W Brent Keeling, Jose Binongo, Michael E Halkos, Bradley G Leshnower, Duc Q Nguyen, Edward P Chen, Eric L Sarin, Jeffrey S Miller, Steven Macheers, Omar M Lattouf, Robert A Guyton, Vinod H Thourani
BACKGROUND: It has been established that outcomes for black patients undergoing coronary artery bypass graft surgery (CABG) are inferior to those of their white counterparts. The purpose of this study was to determine (1) whether rates of multiarterial grafting are different among black patients and white patients, and (2) whether racial differences exist in postoperative outcomes after accounting for grafting strategy. METHODS: A retrospective review of black patients (n = 2,810) and white patients (n = 13,569) who underwent isolated, primary CABG from January 2002 to June 2014 at a US academic institution was performed...
October 4, 2016: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/27699112/continuous-cerebral-hemodynamic-measurement-during-deep-hypothermic-circulatory-arrest
#9
David R Busch, Craig G Rusin, Wanda Miller-Hance, Kathy Kibler, Wesley B Baker, Jeffrey S Heinle, Charles D Fraser, Arjun G Yodh, Daniel J Licht, Kenneth M Brady
While survival of children with complex congenital heart defects has improved in recent years, roughly half suffer neurological deficits suspected to be related to cerebral ischemia. Here we report the first demonstration of optical diffuse correlation spectroscopy (DCS) for continuous and non-invasive monitoring of cerebral microvascular blood flow during complex human neonatal or cardiac surgery. Comparison between DCS and Doppler ultrasound flow measurements during deep hypothermia, circulatory arrest, and rewarming were in good agreement...
September 1, 2016: Biomedical Optics Express
https://www.readbyqxmd.com/read/27561177/comparison-of-endoscopic-robotic-versus-sternotomy-approach-for-the-resection-of-left-atrial-tumors
#10
COMPARATIVE STUDY
Emmanuel Moss, Michael E Halkos, Jeffrey S Miller, Douglas A Murphy
OBJECTIVE: Primary cardiac tumors most commonly occur in the left atrium. The aim of this study was to compare outcomes among patients undergoing isolated left atrial tumor resection via sternotomy or robotic approach. METHODS: From 2003 to 2013, 69 patients underwent isolated left atrial tumor resection at 3 affiliated hospitals with either a sternotomy (n = 39) or robotic approach (n = 30). A retrospective review of prospectively collected data was performed, and outcomes were compared between the sternotomy and robotic groups...
July 2016: Innovations: Technology and Techniques in Cardiothoracic and Vascular Surgery
https://www.readbyqxmd.com/read/27452477/patient-generated-digital-images-after-pediatric-ambulatory-surgery
#11
Matthew W Miller, Rachael K Ross, Christina Voight, Heather Brouwer, Dean J Karavite, Jeffrey S Gerber, Robert W Grundmeier, Susan E Coffin
OBJECTIVE: To describe the use of digital images captured by parents or guardians and sent to clinicians for assessment of wounds after pediatric ambulatory surgery. METHODS: Subjects with digital images of post-operative wounds were identified as part of an on-going cohort study of infections after ambulatory surgery within a large pediatric healthcare system. We performed a structured review of the electronic health record (EHR) to determine how digital images were documented in the EHR and used in clinical care...
July 6, 2016: Applied Clinical Informatics
https://www.readbyqxmd.com/read/27262393/comparison-of-percutaneous-renal-mass-biopsy-and-r-e-n-a-l-nephrometry-score-nomograms-for-determining-benign-versus-malignant-disease-and-low-versus-high-risk-renal-tumors
#12
Takahiro Osawa, Khaled S Hafez, David C Miller, Jeffrey S Montgomery, Todd M Morgan, Ganesh S Palapattu, Alon Z Weizer, Elaine M Caoili, James H Ellis, Lakshmi P Kunju, J Stuart Wolf
OBJECTIVE: To compare the accuracies of renal mass biopsy (RMB) and R.E.N.A.L. nephrometry score (RNS) nomograms for predicting benign versus malignant disease, and low- versus high-risk renal tumors. METHODS: We included 281 renal masses in 277 patients who had complete RNS, preoperative RMB, and final pathology from renal surgery for clinically localized renal tumors. RMB and final pathology were determined to be benign or malignant, and malignancies were classified as low- (Fuhrman grade I/II) or high- (Fuhrman grade III/IV) risk (benign included in low-risk group)...
June 1, 2016: Urology
https://www.readbyqxmd.com/read/27053442/transcatheter-aortic-valve-replacement-versus-surgical-valve-replacement-in-intermediate-risk-patients-a-propensity-score-analysis
#13
RANDOMIZED CONTROLLED TRIAL
Vinod H Thourani, Susheel Kodali, Raj R Makkar, Howard C Herrmann, Mathew Williams, Vasilis Babaliaros, Richard Smalling, Scott Lim, S Chris Malaisrie, Samir Kapadia, Wilson Y Szeto, Kevin L Greason, Dean Kereiakes, Gorav Ailawadi, Brian K Whisenant, Chandan Devireddy, Jonathon Leipsic, Rebecca T Hahn, Philippe Pibarot, Neil J Weissman, Wael A Jaber, David J Cohen, Rakesh Suri, E Murat Tuzcu, Lars G Svensson, John G Webb, Jeffrey W Moses, Michael J Mack, D Craig Miller, Craig R Smith, Maria C Alu, Rupa Parvataneni, Ralph B D'Agostino, Martin B Leon
BACKGROUND: Transcatheter aortic valve replacement (TAVR) with the SAPIEN 3 valve demonstrates good 30 day clinical outcomes in patients with severe aortic stenosis who are at intermediate risk of surgical mortality. Here we report longer-term data in intermediate-risk patients given SAPIEN 3 TAVR and compare outcomes to those of intermediate-risk patients given surgical aortic valve replacement. METHODS: In the SAPIEN 3 observational study, 1077 intermediate-risk patients at 51 sites in the USA and Canada were assigned to receive TAVR with the SAPIEN 3 valve [952 [88%] via transfemoral access) between Feb 17, 2014, and Sept 3, 2014...
May 28, 2016: Lancet
https://www.readbyqxmd.com/read/26970554/laryngeal-examination-in-thyroid-and-parathyroid-surgery-an-american-head-and-neck-society-consensus-statement-ahns-consensus-statement
#14
Catherine F Sinclair, Jeffrey M Bumpous, Bryan R Haugen, Andres Chala, Daniel Meltzer, Barbra S Miller, Neil S Tolley, Jennifer J Shin, Gayle Woodson, Gregory W Randolph
This American Head and Neck Society (AHNS) consensus statement discusses the techniques of laryngeal examination for patients undergoing thyroidectomy and parathyroidectomy. It is intended to help guide all clinicians who diagnose or manage adult patients with thyroid disease for whom surgery is indicated, contemplated, or has been performed. This consensus statement concludes that flexible transnasal laryngoscopy is the optimal laryngeal examination technique, with other techniques including laryngeal ultrasound and stroboscopy being useful in selected scenarios...
June 2016: Head & Neck
https://www.readbyqxmd.com/read/26874864/interictal-epileptiform-discharge-effects-on-neuropsychological-assessment-and-epilepsy-surgical-planning
#15
REVIEW
Daniel L Drane, Jeffrey G Ojemann, Michelle S Kim, Robert E Gross, John W Miller, R Edward Faught, David W Loring
Both animal research and human research suggest that interictal epileptiform discharges (IEDs) may affect cognition, although the significance of such findings remains controversial. We review a wide range of literature with bearing on this topic and present relevant epilepsy surgery cases, which suggest that the effects of IEDs may be substantial and informative for surgical planning. In the first case, we present a patient with epilepsy with left anterior temporal lobe (TL) seizure onset who experienced frequent IEDs during preoperative neuropsychological assessment...
March 2016: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/26296272/the-expanding-role-of-endoscopic-robotics-in-mitral-valve-surgery-1-257-consecutive-procedures
#16
Douglas A Murphy, Emmanuel Moss, Jose Binongo, Jeffrey S Miller, Steven K Macheers, Eric L Sarin, Alexander M Herzog, Vinod H Thourani, Robert A Guyton, Michael E Halkos
BACKGROUND: The role of robotic instruments in mitral valve (MV) surgery continues to evolve. The purpose of this study was to assess the safety, efficacy, and scope of MV surgery using a lateral endoscopic approach with robotics (LEAR) technique. METHODS: From 2006 to 2013, a dedicated LEAR team performed 1,257 consecutive isolated MV procedures with or without tricuspid valve repair or atrial ablation. The procedures were performed robotically through five right-side chest ports with femoral artery or ascending aortic perfusion and balloon occlusion...
November 2015: Annals of Thoracic Surgery
https://www.readbyqxmd.com/read/25873834/prosthetic-valve-endocarditis-with-valvular-obstruction-after-transcatheter-aortic-valve-replacement
#17
Christine Pabilona, Bernard Gitler, Jeffrey A Lederman, Donald Miller, Theodore N Keltz
Patients with severe aortic stenosis who are at high risk for open-heart surgery might be candidates for transcatheter aortic valve replacement (TAVR). To our knowledge, this is the first report of Streptococcus viridans endocarditis that caused prosthetic valve obstruction after TAVR. A 77-year-old man who had undergone TAVR 17 months earlier was admitted because of evidence of prosthetic valve endocarditis. A transthoracic echocardiogram revealed a substantial increase in the transvalvular peak gradient and mean gradient in comparison with an echocardiogram of 7 months earlier...
April 2015: Texas Heart Institute Journal
https://www.readbyqxmd.com/read/25788234/5-year-outcomes-of-transcatheter-aortic-valve-replacement-or-surgical-aortic-valve-replacement-for-high-surgical-risk-patients-with-aortic-stenosis-partner-1-a-randomised-controlled-trial
#18
RANDOMIZED CONTROLLED TRIAL
Michael J Mack, Martin B Leon, Craig R Smith, D Craig Miller, Jeffrey W Moses, E Murat Tuzcu, John G Webb, Pamela S Douglas, William N Anderson, Eugene H Blackstone, Susheel K Kodali, Raj R Makkar, Gregory P Fontana, Samir Kapadia, Joseph Bavaria, Rebecca T Hahn, Vinod H Thourani, Vasilis Babaliaros, Augusto Pichard, Howard C Herrmann, David L Brown, Mathew Williams, Jodi Akin, Michael J Davidson, Lars G Svensson
BACKGROUND: The Placement of Aortic Transcatheter Valves (PARTNER) trial showed that mortality at 1 year, 2 years, and 3 years is much the same with transcatheter aortic valve replacement (TAVR) or surgical aortic valve replacement (SAVR) for high-risk patients with aortic stenosis. We report here the 5-year outcomes. METHODS: We did this randomised controlled trial at 25 hospitals, in Canada (two), Germany (one), and the USA (23). We used a computer-generated randomisation sequence to randomly assign high-risk patients with severe aortic stenosis to either SAVR or TAVR with a balloon-expandable bovine pericardial tissue valve by either a transfemoral or transapical approach...
June 20, 2015: Lancet
https://www.readbyqxmd.com/read/25717118/barbed-sutures-and-wound-complications-in-plastic-surgery-an-analysis-of-outcomes
#19
Roberto Cortez, Eric Lazcano, Travis Miller, Rachel E Hein, Ryan S Constantine, Kendall Anigian, Kathryn E Davis, Jeffrey M Kenkel
BACKGROUND: Barbed sutures may expedite dermal approximation and improve tissue support while requiring less time and material than conventional sutures. Several types of barbed sutures are available, each with unique advantages. OBJECTIVES: The authors sought to determine whether the incidence of complications differed after wound approximation in plastic surgery when various brands of barbed vs nonbarbed traditional sutures were employed. METHODS: The authors conducted a retrospective review of outcomes in body contouring, free flap, and breast reconstruction...
February 2015: Aesthetic Surgery Journal
https://www.readbyqxmd.com/read/25576993/the-primary-open-angle-african-american-glaucoma-genetics-study-baseline-demographics
#20
Emily S Charlson, Prithvi S Sankar, Eydie Miller-Ellis, Meredith Regina, Raymond Fertig, Julia Salinas, Maxwell Pistilli, Rebecca J Salowe, Allison L Rhodes, William T Merritt, Michael Chua, Benjamin T Trachtman, Harini V Gudiseva, David W Collins, Venkata Ramana Murthy Chavali, Charles Nichols, Jeffrey Henderer, Gui-Shuang Ying, Rohit Varma, Eric Jorgenson, Joan M O'Brien
PURPOSE: To describe the baseline characteristics of the Primary Open-Angle African American Glaucoma Genetics (POAAGG) study cohort, the largest African American population with primary open-angle glaucoma (POAG) recruited at a single institution (University of Pennsylvania [UPenn], Department of Ophthalmology, Scheie Eye Institute) to date. DESIGN: Population-based, cross-sectional, case-control study. PARTICIPANTS: A total of 2520 African American subjects aged 35 years or more who were recruited from the greater Philadelphia, Pennsylvania area...
April 2015: Ophthalmology
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