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https://www.readbyqxmd.com/read/28815278/phenotypic-genetic-and-molecular-characterization-of-7b-1-a-conditional-male-sterile-mutant-in-tomato
#1
Anna Pucci, Maurizio Enea Picarella, Andrea Mazzucato
We characterized the photoperiod-sensitive 7B - 1 male-sterile mutant in tomato, showing its allelism with stamenless - 2 . Mapping experiments indicated SlGLO2 , a B-class MADS-box family member, as a strong candidate to underlie the 7B - 1 mutation. The interest in male sterility (MS) dates back to a long time due to its perspective use in hybrid seed production. Here, we characterize 7B-1, a photoperiod-sensitive male-sterile (ms) mutant in tomato (Solanum lycopersicum L.), in which stamens are restored to fertility by permissive growth conditions in short days (SD)...
August 16, 2017: TAG. Theoretical and Applied Genetics. Theoretische und Angewandte Genetik
https://www.readbyqxmd.com/read/28814642/an-indel-in-the-promoter-of-al-activated-malate-transporter-9-selected-during-tomato-domestication-determines-fruit-malate-contents-and-aluminum-tolerance
#2
Jie Ye, Xin Wang, Ti Xu Hu, Feng Xia Zhang, Bing Wang, Chang Xin Li, Tian Xia Yang, Han Xia Li, Yong En Lu, James J Giovannoni, Yuyang Zhang, Zhibiao Ye
Deciphering the mechanism of malate accumulation in plants would contribute to a greater understanding of plant chemistry, which has implications for improving flavor quality in crop species and enhancing human health benefits. However, the regulation of malate metabolism is poorly understood in crops such as tomato (Solanum lycopersicum). Here, we integrated a metabolite-based genome-wide association study (mGWAS) with linkage mapping and gene functional studies to characterize the genetics of malate accumulation in a global collection of tomato accessions with broad genetic diversity...
August 16, 2017: Plant Cell
https://www.readbyqxmd.com/read/28814087/effects-of-sevoflurane-on-apoptosis-bdnf-and-cognitive-functions-in-neonatal-rats
#3
A B Ozer, S Ceribasi, A O Ceribasi, I Demirel, M K Bayar, B Ustundag, A Ileri, O L Erhan
OBJECTIVE: To evaluate the early and late effects of sevoflurane on the neonatal brain. BACKGROUND: Sevoflurane is the most used anaesthetics in neonatal subjects. METHODS: The study included 7-day-old male Wistar-Albino rats (n = 30), which were divided into the two groups according to the anaesthetic received: sevoflurane (S) and control group (C). Half of each group was sacrificed six hours after anaesthesia (early, E) while the remaining subjects were sacrificed six weeks later (late, L)...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28814018/time-varying-impedance-of-the-human-ankle-in-the-sagittal-and-frontal-planes-during-straight-walk-and-turning-steps
#4
Evandro M Ficanha, Guilherme A Ribeiro, Lauren Knop, Mo Rastgaar
This paper describes the methods and experiment protocols for estimation of the human ankle impedance during turning and straight line walking. The ankle impedance of two human subjects during the stance phase of walking in both dorsiflexion plantarflexion (DP) and inversion eversion (IE) were estimated. The impedance was estimated about 8 axes of rotations of the human ankle combining different amounts of DP and IE rotations, and differentiating among positive and negative rotations at 5 instants of the stance length (SL)...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28813830/toward-goal-oriented-robotic-gait-training-the-effect-of-gait-speed-and-stride-length-on-lower-extremity-joint-torques
#5
Robert L McGrath, Margaret Pires-Fernandes, Brian Knarr, Jill S Higginson, Fabrizio Sergi
Robot-assisted gait training is becoming increasingly common to support recovery of walking function after neurological injury. How to formulate controllers capable of promoting desired features in gait, i.e. goals, is complicated by the limited understanding of the human response to robotic input. A possible method to formulate controllers for goal-oriented gait training is based on the analysis of the joint torques applied by healthy subjects to modulate such goals. The objective of this work is to understand how sagittal plane joint torque is affected by two important gait parameters: gait speed (GS) and stride length (SL)...
July 2017: IEEE ... International Conference on Rehabilitation Robotics: [proceedings]
https://www.readbyqxmd.com/read/28811540/ultralow-lattice-thermal-conductivity-of-the-random-multilayer-structure-with-lattice-imperfections
#6
Pranay Chakraborty, Lei Cao, Yan Wang
Randomizing the layer thickness of superlattices (SL) can lead to localization of coherent phonons and thereby reduces the lattice thermal conductivity κ l . In this work, we propose strategies that can suppress incoherent phonon transport in the above random multilayer (RML) structure to further reduce κ l . Molecular dynamics simulations are conducted to investigate phonon heat conduction in SLs and RMLs with lattice imperfections. We found that interfacial species mixing enhances thermal transport across single interfaces and few-period SLs through the phonon "bridge" mechanism, while it substantially reduces the κ l of many-period SLs by breaking the phonon coherence...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28811534/distinct-projection-patterns-of-different-classes-of-layer-2-principal-neurons-in-the-olfactory-cortex
#7
Camille Mazo, Julien Grimaud, Yasuyuki Shima, Venkatesh N Murthy, C Geoffrey Lau
The broadly-distributed, non-topographic projections to and from the olfactory cortex may suggest a flat, non-hierarchical organization in odor information processing. Layer 2 principal neurons in the anterior piriform cortex (APC) can be divided into 2 subtypes: semilunar (SL) and superficial pyramidal (SP) cells. Although it is known that SL and SP cells receive differential inputs from the olfactory bulb (OB), little is known about their projections to other olfactory regions. Here, we examined axonal projections of SL and SP cells using a combination of mouse genetics and retrograde labeling...
August 15, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28809432/intranasal-administration-of-brain-targeted-hp-%C3%AE-cd-chitosan-nanoparticles-for-delivery-of-scutellarin-a-compound-with-protective-effect-in-cerebral-ischaemia
#8
Shanshan Liu, Paul C Ho
OBJECTIVES: Scutellarin (SCU) is a traditional Chinese medicine used for the treatment of ischaemic cerebrovascular disease, but its clinic applications have been limited due to its poor water solubility, poor bioavailability and short half-life. In comparison with the conventional oral and intravenous administration, nasal administration may help targeting the drug more directly to brain. Thus, we proposed to employ a novel SCU-loaded HP-β-CD/chitosan nanoparticles (CD/CS-SCU-NPs) to deliver SCU to brain through the nasal route...
August 15, 2017: Journal of Pharmacy and Pharmacology
https://www.readbyqxmd.com/read/28809396/ipa1-functions-as-a-downstream-transcription-factor-repressed-by-d53-in-strigolactone-signaling-in-rice
#9
Xiaoguang Song, Zefu Lu, Hong Yu, Gaoneng Shao, Jinsong Xiong, Xiangbing Meng, Yanhui Jing, Guifu Liu, Guosheng Xiong, Jingbo Duan, Xue-Feng Yao, Chun-Ming Liu, Hongqing Li, Yonghong Wang, Jiayang Li
Strigolactones (SLs), a group of carotenoid derived terpenoid lactones, are root-to-shoot phytohormones suppressing shoot branching by inhibiting the outgrowth of axillary buds. DWARF 53 (D53), the key repressor of the SL signaling pathway, is speculated to regulate the downstream transcriptional network of the SL response. However, no downstream transcription factor targeted by D53 has yet been reported. Here we report that Ideal Plant Architecture 1 (IPA1), a key regulator of the plant architecture in rice, functions as a direct downstream component of D53 in regulating tiller number and SL-induced gene expression...
August 15, 2017: Cell Research
https://www.readbyqxmd.com/read/28806832/-dorsal-ligamentoplasty-for-posttraumatic-scapholunate-dissociation
#10
Ralf Bajinski, Joachim Gülke, Martin Mentzel, Florian Sigloch, Moritz Dustmann, Nikolaus Johannes Wachter
Scapholunate dissociation in stages 2 and 3 may lead to posttraumatic damage if left untreated. Different types of treatment have been described, including capsulodesis, tenodesis, and others. The purpose of all procedures is to avoid palmar shift of the distal scaphoid resulting in secondary arthritis (SLAC wrist). This study aimed to evaluate a modified dorsal ligamentoplasty in second- and third-degree scapholunate dissociation in a prospective study design. Furthermore, the study aimed to find out if there is a correlation between radiological and clinical parameters at follow-up and whether or not a SLAC wrist can be avoided...
August 2017: Handchirurgie, Mikrochirurgie, Plastische Chirurgie
https://www.readbyqxmd.com/read/28805900/effects-of-dietary-tannins-on-total-and-extractable-nutrients-from-manure
#11
J J Halvorson, S L Kronberg, A E Hagerman
The effects of condensed tannins on N dynamics in ruminants have been a topic of research for some time, but much less work has focused on their impacts on other nutrients in manure. A 4 × 4 Latin square trial was used to determine if intake of sericea lespedeza (; SL; a condensed tannin source), at 0, 10, 20, or 40% of the diet (as-fed basis), would affect concentrations of nutrients in manure and patterns of total excretion when offered with alfalfa (; ALF) to sheep. With SL additions, average daily manure production increased linearly ( ≤ 0...
August 2017: Journal of Animal Science
https://www.readbyqxmd.com/read/28803223/social-responsibilities-of-a-physician-reflections-of-major-general-s-l-bhatia-1891-1981
#12
Radhika Hegde, Mario Vaz
This paper examines various documents written by Major General SL Bhatia CIE, MC, IMS from the 1920s to the1960s on the "Social Responsibilities of a Physician". His reflections are of historical significance, since they provide us with an insight into the challenges confronting the people who attempted to rebuild a nation plagued by poverty resulting from fractured agricultural growth, a feudalistic social structure and the regional inequalities that accompany it, and prolonged imperial rule, among other things...
July 25, 2017: Indian Journal of Medical Ethics
https://www.readbyqxmd.com/read/28799436/immunotherapy-based-approaches-in-myelofibrosis
#13
Lucia Masarova, Srdan Verstovsek, Hagop Kantarjian, Naval Daver
Aberrant regulation of the immune system with up-regulation of pro-inflammatory cytokines contributes to disease pathophysiology in myelofibrosis (MF). Therapeutic options for MF associated anemia, thrombocytopenia, and bone marrow fibrosis remain limited. Areas covered: This review focuses on immune based therapies in MF, including immunomodulatory imide drugs (IMiDs), interferons, monoclonal antibodies and targeted agents (SL-401), and checkpoint inhibitors. Published literature was reviewed using available databases (PubMed, Cochrane, Scopus) and web pages (clinicaltrials...
August 11, 2017: Expert Review of Hematology
https://www.readbyqxmd.com/read/28796538/oxygen-therapy-for-interstitial-lung-disease-physicians-perceptions-and-experiences
#14
Yet H Khor, Nicole Sl Goh, Christine F McDonald, Anne E Holland
RATIONALE: Domiciliary oxygen therapy (DOT) is commonly prescribed for patients with interstitial lung disease (ILD) and hypoxaemia, although evidence supporting benefit is limited. OBJECTIVES: The aim of this study was to explore perspectives of respiratory physicians about DOT in patients with ILD. METHODS: A qualitative study was undertaken with 26 respiratory physicians from Australia. Interviews were transcribed verbatim and coded independently by two investigators...
August 10, 2017: Annals of the American Thoracic Society
https://www.readbyqxmd.com/read/28794439/maternal-low-intensity-physical-exercise-prevents-obesity-in-offspring-rats-exposed-to-early-overnutrition
#15
Tatiane Aparecida Ribeiro, Laize Peron Tófolo, Isabela Peixoto Martins, Audrei Pavanello, Júlio Cezar de Oliveira, Kelly Valério Prates, Rosiane Aparecida Miranda, Claudinéia Conationi da Silva Franco, Rodrigo Mello Gomes, Flávio Andrade Francisco, Vander Silva Alves, Douglas Lopes de Almeida, Veridiana Mota Moreira, Kesia Palma-Rigo, Elaine Vieira, Gabriel Sergio Fabricio, Marcos Ricardo da Silva Rodrigues, Wilson Rinaldi, Ananda Malta, Paulo Cezar de Freitas Mathias
Low intensity exercise during pregnancy and lactation may create a protective effect against the development of obesity in offspring exposed to overnutrition in early life. To test these hypotheses, pregnant rats were randomly assigned into 2 groups: Sedentary and Exercised, low intensity, on a rodent treadmill at 30% VO2Max /30-minute/session/3x/week throughout pregnancy and the lactation. Male offspring were raised in small litters (SL, 3 pups/dam) and normal litters (NL, 9 pups/dam) as models of early overnutrition and normal feed, respectively...
August 9, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28792774/interfacial-clustering-triggered-fluorescence-phosphorescence-dual-solvoluminescence-of-metal-nanoclusters
#16
Taiqun Yang, Shan Dai, Songqiu Yang, Li Chen, Pengcheng Liu, Kailong Dong, Jiasheng Zhou, Yuting Chen, Haifeng Pan, Sanjun Zhang, Jinquan Chen, Kun Zhang, Peng Wu, Jianhua Xu
The fluorescence-phosphorescence dual solvoluminescence of water-soluble metal nanoclusters (NCs) at room temperature was successfully achieved by a simple solvent-stimulated strategy. The strong interaction between carboxylate ligands and metal core at the nanoscale interface not only induces rigid conformations of carbonyl groups, but also affords a perfect carbonyl cluster, that acts as an exact chromophore of metal NCs for aggregation-induced emission (AIE) mechanics. The clustering of carbonyl groups bearing on the polymer backbone chain is promoted by new discovered n→π* noncovalent interactions...
August 9, 2017: Journal of Physical Chemistry Letters
https://www.readbyqxmd.com/read/28791819/decreased-sl-selectin-serum-levels-in-sleep-apnea-syndrome-patients-with-cardiovascular-diseases
#17
Monika Kosacka, Irena Porębska, Renata Jankowska
BACKGROUND: Obstructive sleep apnea syndrome (OSA) is a common disorder associated with an increased risk of cardiovascular diseases. OBJECTIVES: sL-selectin is an adhesion molecule released from the surface of leukocytes as they are activated and may inhibit leukocyte attachment to the endothelium. The aim of this study was to evaluate sL-selectin serum levels in OSA patients with cardiovascular diseases. MATERIAL AND METHODS: A total of 163 OSA patients were enrolled in the study...
May 2017: Advances in Clinical and Experimental Medicine: Official Organ Wroclaw Medical University
https://www.readbyqxmd.com/read/28790914/ethnopharmacological-and-chemical-characterization-of-salvia-species-used-in-valencian-traditional-herbal-preparations
#18
Vanessa Martínez-Francés, Emeline Hahn, Segundo Ríos, Diego Rivera, Eike Reich, Roser Vila, Salvador Cañigueral
In Valencia Region (Spain), some wild and cultivated sages are used for medicinal purposes. Among them, Salvia officinalis subsp. lavandulifolia (SL) is widely employed and known for production of Spanish sage oil and herbal products. Nevertheless, it shares the market with S. blancoana subsp. mariolensis (SB) and, to a lesser extent, with their hybrid S. x hegelmaieri (SH). The knowledge on these two species is far low and confusion between them is possible. The aim of the present paper is to improve the ethnopharmacological, morphological and chemical knowledge of these sages, and to contribute to setting up quality specifications for improving identification and distinction from other Salvia species, such as, S...
2017: Frontiers in Pharmacology
https://www.readbyqxmd.com/read/28772496/influence-of-resin-composition-on-the-defect-formation-in-alumina-manufactured-by-stereolithography
#19
Emil Johansson, Oscar Lidström, Jan Johansson, Ola Lyckfeldt, Erik Adolfsson
Stereolithography (SL) is a technique allowing additive manufacturing of complex ceramic parts by selective photopolymerization of a photocurable suspension containing photocurable monomer, photoinitiator, and a ceramic powder. The manufactured three-dimensional object is cleaned and converted into a dense ceramic part by thermal debinding of the polymer network and subsequent sintering. The debinding is the most critical and time-consuming step, and often the source of cracks. In this study, photocurable alumina suspensions have been developed, and the influence of resin composition on defect formation has been investigated...
February 8, 2017: Materials
https://www.readbyqxmd.com/read/28772255/salt-responsive-physiological-photosynthetic-and-biochemical-attributes-at-early-seedling-stage-for-screening-soybean-genotypes
#20
D B Shelke, M Pandey, G C Nikalje, B N Zaware, P Suprasanna, T D Nikam
Salt stress affects all the stages of plant growth however seed germination and early seedling growth phases are more sensitive and can be used for screening of crop germplasm. In this study, we aimed to find the most effective indicators of salt tolerance for screening ten genotypes of soybean (SL-295, Gujosoya-2, PS-1042, PK-1029, ADT-1, RKS-18, KDS-344, MAUS-47, Bragg and PK-416). The principal component analysis (PCA) resulted in the formation of three different clusters, salt sensitive (SL-295, Gujosoya-2, PS-1042 and ADT-1), salt tolerant (MAUS-47, Bragg and PK-416) and moderately tolerant/sensitive (RKS-18, PK-1029 and KDS-344) suggesting that there was considerable genetic variability for salt tolerance in the soybean genotypes...
July 16, 2017: Plant Physiology and Biochemistry: PPB
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