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https://www.readbyqxmd.com/read/28528753/healthcare-access-and-quality-index-based-on-mortality-from-causes-amenable-to-personal-health-care-in-195-countries-and-territories-1990-2015-a-novel-analysis-from-the-global-burden-of-disease-study-2015
#1
(no author information available yet)
BACKGROUND: National levels of personal health-care access and quality can be approximated by measuring mortality rates from causes that should not be fatal in the presence of effective medical care (ie, amenable mortality). Previous analyses of mortality amenable to health care only focused on high-income countries and faced several methodological challenges. In the present analysis, we use the highly standardised cause of death and risk factor estimates generated through the Global Burden of Diseases, Injuries, and Risk Factors Study (GBD) to improve and expand the quantification of personal health-care access and quality for 195 countries and territories from 1990 to 2015...
May 18, 2017: Lancet
https://www.readbyqxmd.com/read/28523356/evaluation-of-height-dependent-and-height-independent-methods-of-estimating-baseline-serum-creatinine-in-critically-ill-children
#2
Erin Hessey, Rami Ali, Marc Dorais, Geneviève Morissette, Michael Pizzi, Nikki Rink, Philippe Jouvet, Jacques Lacroix, Véronique Phan, Michael Zappitelli
BACKGROUND: Baseline serum creatinine (bSCr) is required for diagnosing acute kidney injury (AKI). In children, bSCr is commonly defined as the lowest measurement within 3 months of admission. Measured values are often missing and estimating bSCr using height-based glomerular filtration rate (GFR) equations is problematic when height is unavailable. METHODS: This is a retrospective cohort study including 538 children admitted to the intensive care unit (ICU) between 2003 and 2005 at two centers in Canada, with measured bSCr, height, and ICU-SCr values...
May 18, 2017: Pediatric Nephrology: Journal of the International Pediatric Nephrology Association
https://www.readbyqxmd.com/read/28520695/calreticulin-ameliorates-hypoxia-reoxygenation-induced-human-microvascular-endothelial-cell-injury-by-inhibiting-autophagy
#3
You Wang, Tian-Qi Tao, Dan-Dan Song, Xiu-Hua Liu
BACKGROUND: Autophagy has been found to be involved in myocardial ischemia/reperfusion injury. However, the underlying mechanism and significance of autophagy in reperfusion injury remain unclear. Herein, we evaluated the effects of exogenous calreticulin (CRT) on autophagy in hypoxia/reoxygenation (H/R)-treated human microvascular endothelial cells (MECs). METHODS: Human MECs were pretreated with CRT (25 pg/mL) for 30 min, followed by exposure in an incubator filled with a gas mixture of 90% N2, 5% O2, and 5% CO2 for 8-h hypoxia...
May 17, 2017: Shock
https://www.readbyqxmd.com/read/28515563/secondary-eating-disorder-a-reality-case-report-of-post-brain-injury-sequelae
#4
Aparna Das, Deeksha Elwadhi, Manushree Gupta
Traumatic brain injury (TBI) can lead to changes in eating behavior patterns. This report describes the case of a patient with alcohol dependence presenting with behavioral changes and eating disorder following frontal lobe trauma. A 42-year-old male, premorbidly well-adjusted presented with alcohol use in dependent pattern for years. He sustained a subdural hematoma in the frontal lobe following a road traffic accident 10 years back. Post-TBI, the patient, started having low frustration tolerance, aggressive outbursts, disinhibition, difficulty in persisting with tasks, apathy, amotivation, and craving for food with inability to control intake on the sight of food...
March 2017: Indian Journal of Psychological Medicine
https://www.readbyqxmd.com/read/28513398/-nurse-believed-in-me-and-helped-me-piece-my-life-back-together
#5
Diane Palmer
While serving in the Royal Anglian Regiment in Afghanistan in 2007, I was seriously injured by friendly fire. I was left with significant physical and psychological injuries from the blast.
May 17, 2017: Nursing Standard
https://www.readbyqxmd.com/read/28508521/an-incidental-diffuse-midline-glioma-found-at-autopsy
#6
Meggen Walsh, William Hamilton, Vektra Casler, Anthony Yachnis
This case shows an unexpected midline glioma found at autopsy. Two siblings were riding on a single bicycle on the side of a road. The 13-year-old brother was seated and steering the bicycle, while the 14-year-old sister held onto the back. The bicycle veered left into traffic and was struck by a vehicle. The siblings were admitted to the local Level 1 trauma center, but both later succumbed to injuries. Autopsies were performed on the children, including brains for neuropathologic evaluation. The brother was found to have an infiltrating astrocytoma located in the left middle cerebellar peduncle, with extension to the pons and medulla...
May 16, 2017: Journal of Forensic Sciences
https://www.readbyqxmd.com/read/28506115/predictors-of-work-participation-for-m%C3%A4-ori-three-months-after-injury
#7
Emma H Wyeth, Brett Maclennan, Michelle Lambert, Gabrielle Davie, Rebbecca Lilley, Sarah Derrett
An important rehabilitation outcome for injured Māori is timely sustainable return to work. This paper identifies the factors influencing working after injury in an attempt to reduce the individual, social and economic costs. Māori participants in the Prospective Outcomes of Injury Study were interviewed, about pre-injury and injury-related factors. Among Māori participants, 521 were working for pay prior to injury; 64% were working three months post-injury. Factors identified, using modified Poisson regression, that predicted working include: financial security (aRR = 1...
May 16, 2017: Archives of Environmental & Occupational Health
https://www.readbyqxmd.com/read/28505998/-i-really-hope-it-comes-back-olfactory-impairment-following-traumatic-brain-injury-a-longitudinal-study
#8
Melanie Drummond, Jacinta Douglas, John Olver
BACKGROUND: Olfactory Impairment (OI) can present in up to 66% of all individuals following traumatic brain injury (TBI) and can have significant implications for everyday life. OBJECTIVE: To investigate the predictive factors, natural progression and consequences of OI in following TBI in individuals 12 months post injury. METHODS: In this prospective longitudinal study, 37 adults (28 males, 9 females), mean age 42.3 years (SD 19.4), with predominately severe TBI (mean length of posttraumatic amnesia (PTA) 28...
May 11, 2017: NeuroRehabilitation
https://www.readbyqxmd.com/read/28503674/identifying-brain-nociceptive-information-transmission-in-patients-with-chronic-somatic-pain
#9
Don A Davis, Mariam E Ghantous, Melissa A Farmer, Alexis T Baria, A Vania Apkarian
INTRODUCTION: Recent advances regarding mechanisms of chronic pain emphasize the role of corticolimbic circuitry in predicting risk for chronic pain, independently from site of injury-related parameters. These results compel revisiting the role of peripheral nociceptive signaling in chronic pain. We address this issue by examining what brain circuitry transmit information regarding the intensity of chronic pain and how this information may be related to a common co-morbidity, depression...
October 2016: Pain Reports (Baltimore, Md.)
https://www.readbyqxmd.com/read/28501675/predicting-heavy-episodic-drinking-using-an-extended-temporal-self-regulation-theory
#10
Nicola Black, Barbara Mullan, Louise Sharpe
INTRODUCTION: Alcohol consumption contributes significantly to the global burden from disease and injury, and specific patterns of heavy episodic drinking contribute uniquely to this burden. Temporal self-regulation theory and the dual-process model describe similar theoretical constructs that might predict heavy episodic drinking. The aims of this study were to test the utility of temporal self-regulation theory in predicting heavy episodic drinking, and examine whether the theoretical relationships suggested by the dual-process model significantly extend temporal self-regulation theory...
April 28, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28499991/an-interactive-simulator-for-imposing-virtual-musculoskeletal-dynamics
#11
Christopher Hasson
OBJECTIVE: Disease processes are often marked by both neural and muscular changes that alter movement control and execution, but these adaptations are difficult to tease apart because they occur simultaneously. This is addressed by swapping an individual's limb dynamics with a neurally-controlled facsimile using an interactive musculoskeletal simulator (IMS) that allows controlled modifications of musculoskeletal dynamics. This paper details the design and operation of the IMS, quantifies and describes human adaptation to the IMS, and determines whether the IMS allows users to move naturally, a prerequisite for manipulation experiments...
May 10, 2017: IEEE Transactions on Bio-medical Engineering
https://www.readbyqxmd.com/read/28498625/biomechanics-of-the-human-uterus
#12
REVIEW
Kristin M Myers, David Elad
The appropriate biomechanical function of the uterus is required for the execution of human reproduction. These functions range from aiding the transport of the embryo to the implantation site, to remodeling its tissue walls to host the placenta, to protecting the fetus during gestation, to contracting forcefully for a safe parturition and postpartum, to remodeling back to its nonpregnant condition to renew the cycle of menstruation. To serve these remarkably diverse functions, the uterus is optimally geared with evolving and contractile muscle and tissue layers that are cued by chemical, hormonal, electrical, and mechanical signals...
May 12, 2017: Wiley Interdisciplinary Reviews. Systems Biology and Medicine
https://www.readbyqxmd.com/read/28497321/predicting-cumulative-and-maximum-brain-strain-measures-from-hybridiii-head-kinematics-a-combined-laboratory-study-and-post-hoc-regression-analysis
#13
Brooklynn M Knowles, Christopher R Dennison
Due to growing concern on brain injury in sport, and the role that helmets could play in preventing brain injury caused by impact, biomechanics researchers and helmet certification organizations are discussing how helmet assessment methods might change to assess helmets based on impact parameters relevant to brain injury. To understand the relationship between kinematic measures and brain strain, we completed hundreds of impacts using a 50th percentile Hybrid III head-neck wearing an ice hockey helmet and input three-dimensional impact kinematics to a finite element brain model called the Simulated Injury Monitor (SIMon) (n = 267)...
May 11, 2017: Annals of Biomedical Engineering
https://www.readbyqxmd.com/read/28494521/topical-1-propranolol-cream-promotes-cutaneous-wound-healing-in-spontaneously-diabetic-mice
#14
Zhifang Zheng, Yishu Liu, Yu Yang, Jianbing Tang, Biao Cheng
Diabetic foot ulcers (DFUs) are a constant threat to diabetic patients and can lead to amputations and even death. Intralesional administration of propranolol in diabetic wounds has not been reported previously. This study aimed to investigate the efficacy of propranolol cream in diabetic wounds. Fifty-six spontaneously diabetic mice were divided into the propranolol group and the control group. After preparing full-thickness wounds on the back of the mice, 1% propranolol cream was topically applied to wounds in the experimental group and 0% propranolol cream in controls...
May 11, 2017: Wound Repair and Regeneration
https://www.readbyqxmd.com/read/28491886/the-effect-of-the-number-of-carries-among-college-running-backs-on-future-injury-risk-and-performance-in-the-national-football-league
#15
Matthew J Kraeutler, John W Belk, Eric C McCarty
BACKGROUND: There has been speculation that running backs with an excessive number of carries in college are less likely to be successful in the National Football League (NFL). PURPOSE: To determine whether there is a correlation between number of carries by college running backs and future performance and injury risk in the NFL. STUDY DESIGN: Cohort study; Level of evidence, 3. METHODS: Using the ESPN archives of National Collegiate Athletic Association and NFL running backs, the following inclusion criteria were used: running backs who played their last college season from 1999 through 2012 and who were drafted in the first 4 rounds of the NFL draft following their college career...
April 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28491203/traumatic-lumbar-vertebral-ring-apophysis-fracture-with-disk-herniation-in-an-adolescent
#16
Geetanjalee Kadam, Kaustubh Narsinghpura, Sonali Deshmukh, Sanjay Desai
We present a case of a 15-year-old male with history of back pain and bilateral lower limb radiculopathy due to fall. The magnetic resonance imaging scan showed disc bulge at L2-L3 level causing compression on contained nerve roots. In this case, computed tomography scan was indispensable for diagnosis and classification of the vertebral apophyseal fracture and to guide appropriate further management. Apophyseal ring fracture is an uncommon cause of back pain with radiculopathy in adolescents and athletes. High degree of suspicion is necessary to differentiate these injuries from disc herniation so as to further guide appropriate conservative or surgical management...
June 2017: Radiology case reports
https://www.readbyqxmd.com/read/28487040/immediate-postpartum-neurological-deficits-in-the-lower-extremity-a-prospective-observational-study
#17
A Richards, T McLaren, M J Paech, E A Nathan, E Beattie, N McDonnell
BACKGROUND: Neurological deficits noted immediately after childbirth are usually various obstetric neuropathies, but prospective studies are limited. The main study aim was to quantify and describe immediate postpartum neurological deficits of the lower extremity, including the buttocks. METHODS: A prospective observational study of postpartum women delivering in a single maternity hospital during three months of 2016. Among 1147 eligible women, 1019 were screened for symptoms of lower extremity numbness or weakness within eight to 32hours of delivery...
April 8, 2017: International Journal of Obstetric Anesthesia
https://www.readbyqxmd.com/read/28486345/diagnosed-chronic-health-conditions-among-injured-workers-with-permanent-impairments-and-the-general-population
#18
Rebecca Casey, Peri J Ballantyne
OBJECTIVE: To profile chronic health conditions of an injured worker sample before and after workplace injury and compare injured workers to a matched community sample. METHODS: Logistic regression analyses compared risk of certain chronic health conditions for permanently disabled injured workers in the pre- and post-injury periods to comparator subsamples from the Canadian Community Health Surveys 2003 and 2009/2010. RESULTS: There were notable health differences between the injured worker and comparator samples for the post-injury period...
May 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28484883/delayed-chance-fracture-pattern-injury-in-a-case-of-skeletal-fluorosis
#19
Srikanth Reddy Dumpa, Siddharth N Aiyer, Sreekanth Reddy Rajoli, Ajoy Prasad Shetty, S Rajasekaran
PURPOSE: To document a rare complication of a delayed 'chance fracture pattern'-type injury through the proximal end of a pedicle screw construct in the clinical scenario of skeletal fluorosis. METHODS: A 72-year-old man with fluorosis presented following a fall which resulted in a T12-L1 fracture. Investigations revealed an unstable three-column injury, so the patient was treated with surgical stabilisation using pedicle screw fixation from T11 to L2. He presented 1 month following surgery with worsening back pain...
May 8, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28480093/the-public-health-threat-of-road-traffic-accidents-in-nigeria-a-call-to-action
#20
REVIEW
Noc Onyemaechi, U R Ofoma
Public health experts worldwide concede that there is a global epidemic of road traffic accidents (RTA). Globally, RTA is the leading cause of injury-related deaths. In Nigeria, injuries and deaths resulting from RTA are on the rise and are Nigeria's third-leading cause of overall deaths, the leading cause of trauma-related deaths and the most common cause of disability. Do RTA constitute a public health problem in Nigeria? If so, is there a pragmatic approach to combat this problem? A systematic literature search using the advanced features of various databases such as PubMed, Scopus, Embase, Google, and directory of open access journals was carried out using the key words " RTA, public health problem, government response, Nigeria...
July 2016: Annals of Medical and Health Sciences Research
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