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https://www.readbyqxmd.com/read/28651421/-effects-of-change-in-the-activity-of-vacuolar-adenosine-triphosphatase-of-myocardial-lysosome-on-myocardial-damage-in-rats-after-severe-burn-and-its-mechanism
#1
X P Yan, D X Zhang, T T Yan, Q Zhang, J Z Jia, Y S Huang
Objective: To explore the effects of change of activity of vacuolar adenosine triphosphatase (V-ATPase) of myocardial lysosome on myocardial damage in rats after severe burn and its mechanism. Methods: The myocardial lysosomes were extracted from the hearts of 12 SD rats with ultra-high speed gradient density centrifugation, then Western blotting and transmission electron microscope observation were conducted for identification. One hundred and twenty rats were divided into pure burn group, ATP group, normal control group, and bafilomycin group according to the random number table, with 30 rats in each group...
May 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28648042/-effects-of-lappaconitine-on-pain-and-inflammatory-response-of-severely-burned-rats-and-the-mechanism
#2
C L Yang, Z R Wei, T H Zhang, X Q Zeng, B H Wu
Objective: To explore the effects of lappaconitine (LA) on pain and inflammatory response of severely burned rats and the mechanism. Methods: Forty SD rats were divided into healthy+ normal saline group, sham injury+ normal saline group, pure burn group, burn+ LA group, and healthy+ LA group according to the random number table (the same dividing method below), with 8 rats in each group. Rats in pure burn and burn+ LA groups were inflicted with about 32% total body surface area deep partial-thickness scald (hereinafter referred to as burn) on the back and right hind...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28648040/-effects-of-seawater-immersion-on-the-inflammatory-response-and-oxygen-free-radical-injury-of-rats-with-superficial-partial-thickness-scald-at-early-stage
#3
Y X Yang, J H Wang, L Liu, Q Zou, Y Zhang, Z Bai
Objective: To study the effects of seawater immersion on the inflammatory response and oxygen free radical injury of rats with superficial-thickness scald at early stage. Methods: Seventy Wistar rats were divided into healthy control group (HC, n=7), pure scald group (PS, n=21), scald+ fresh water immersion group (SF, n=21), and scald+ seawater immersion group (SS, n=21) according to the random number table. Rats in group HC did not receive any treatment, while 5% total body surface area superficial partial-thickness scald was made on the back of rats in the latter three groups...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28648038/-effects-of-na-h-exchanger-1-inhibitor-on-intestinal-injury-of-rats-with-burn-sepsis-and-the-mechanism
#4
W P Li, G Y Zhao, X K Yang
Objective: To observe the effects of Na(+) /H(+) exchanger 1 (NHE1) inhibitor on intestinal injury of rats with burn sepsis, and to explore the possible mechanism preliminarily. Methods: Ninety SD rats were divided into control group, pure sepsis group, and NHE1 inhibitor group according to the random number table, with 30 rats in each group. Full-thickness scald (hereinafter referred to as burn) model with 20% total body surface area were reproduced on the back of rats in pure sepsis and NHE1 inhibitor groups, and then 50 μL liquid of Pseudomonas aeruginosa ATCC 27853 (2×10(5) colony forming unit/mL) were injected into the center of wounds on the back...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28648037/-effects-of-activating-silent-information-regulator-1-on-early-kidney-damage-in-rats-with-severe-burn
#5
X Z Bai, T He, Y Liu, W Zhang, F Han, C Yang, W X Cai, Y H Jia, J H Shi, J T Han, L L Su, D H Hu
Objective: To investigate the effects of activating silent information regulator 1 (SIRT1) on the early kidney damage in rats with severe burn. Methods: Thirty healthy male SD rats were divided into sham injury group (SI), pure burn group (PB), and SIRT1 activator group (SA) according to the random number table, with 10 rats in each group. Rats in groups PB and SA were inflicted with 30% total body surface area full-thickness scald (hereinafter referred to as burn) on the back. Immediately after injury, rats in group PB were intraperitoneally injected with normal saline in the dosage of 50 mL/kg, and those in group SA with 1 mg/mL (final mass concentration) resveratrol in the dosage of 50 mL/kg...
June 20, 2017: Zhonghua Shao Shang za Zhi, Zhonghua Shaoshang Zazhi, Chinese Journal of Burns
https://www.readbyqxmd.com/read/28645455/kinematic-chain-reactions-on-trunk-and-dynamic-postural-steadiness-in-subjects-with-recurrent-low-back-pain
#6
Paul S Sung, Michael J Maxwell
Although subjects with recurrent low back pain (LBP) demonstrate altered trunk control, the kinematic and kinetic responses of the trunk have not been carefully investigated. This study was conducted to compare the standing time, spine range of motion (ROM), and dynamic postural steadiness index (DPSI) based on visual condition between subjects with and without recurrent LBP during upright one leg standing. Sixty-three individuals participated in the study, including 34 control subjects and 29 subjects with recurrent LBP...
June 8, 2017: Journal of Biomechanics
https://www.readbyqxmd.com/read/28644733/trends-of-atv-use-and-associated-injury-on-saskatchewan-farms
#7
Lynne Clay, Stephan Milosavljevic, Niels Koehncke, James Dosman, Catherine Trask
PURPOSE: All-terrain vehicles (ATV's) are a hazardous source of injury in many contexts and geographical regions, but to date have not been investigated in Saskatchewan. METHODS: Baseline surveys from the Saskatchewan Farm Injury Project were examined at two time points in terms of: 1) rates and correlated characteristics of reported ATV use; and 2) qualitative content analysis of injury events involving ATVs. The sample of eligible farmers was 2972 in 2007 and 1702 in 2013...
June 23, 2017: Journal of Occupational and Environmental Hygiene
https://www.readbyqxmd.com/read/28644193/heel-raised-foot-posture-do-not-affect-trunk-and-lower-extremity-biomechanics-during-a-barbell-back-squat-in-recreational-weightlifters
#8
Szu-Ping Lee, Carrie Gillis, Javier J Ibarra, Derek Oldroyd, Ryan Zane
It is claimed that weightlifting shoes with a raised heel may lead to a more upright trunk posture, and thus reduce the risk of back injuries during a barbell back squat. These proclaimed biomechanical effects have not been thoroughly investigated. The purpose of this study was to compare trunk and lower extremity biomechanics during barbell back squats in 3 foot postures.14 recreational weightlifters (7 male and 7 female) between the ages of 18-50 performed barbell back squats in 3 conditions (barefoot on a flat surface, barefoot on a heel-raised platform, and wearing heel-raised weightlifting shoes) at 80% of their 1-RM...
June 19, 2017: Journal of Strength and Conditioning Research
https://www.readbyqxmd.com/read/28643066/solving-the-surgeon-ergonomic-crisis-with-surgical-exosuit
#9
Shanglei Liu, Daniel Hemming, Ran B Luo, Jessica Reynolds, Jonathan C Delong, Bryan J Sandler, Garth R Jacobsen, Santiago Horgan
INTRODUCTION: The widespread adoption of laparoscopic surgery has put new physical demands on the surgeon leading to increased musculoskeletal disorders and injuries. Shoulder, back, and neck pains are among the most common complaints experienced by laparoscopic surgeons. Here, we evaluate the feasibility and efficacy of a non-intrusive progressive arm support exosuit worn by surgeons under the sterile gown to reduce pain and fatigue during surgery. METHODS AND PROCEDURES: This is a prospective randomized crossover study approved by the Internal Review Board (IRB)...
June 22, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28642835/differential-carbonyl-stress-expression-in-the-intervertebral-disc-between-singular-and-persistent-mechanical-injuries
#10
Itaru Hibino, Simon Tang
Low back pain is a significant public health problem worldwide. Intervertebral disc degeneration is most significant known risk factor for low back pain. Yet the mechanisms of degeneration remain relatively unknown. Carbonyl stress and oxidation have been implicated in cartilage and fibrocartilage degeneration. Here we investigate the role of oxidative stress and carbonyl production in the intervertebral disc after mechanical injury using an in vitro organ model of the mouse functional spine unit. We use a single-stab insult to model mild injury, and the three-stab insult to model severe trauma...
2017: Nagoya Gakuin Daigaku Ronshu Igaku Kenko Kagaku Supotsu Kagakuhen
https://www.readbyqxmd.com/read/28640103/occupational-injuries-among-pediatric-orthopedic-surgeons-how-serious-is-the-problem
#11
Abdulmonem M Alsiddiky, Raheef Alatassi, Saad M Altamimi, Mahdi M Alqarni, Saud M Alfayez
In this cross-sectional study, we surveyed all pediatric orthopedic surgeons in Saudi Arabia using an anonymous electronic questionnaire composed of 23 items to identify the rate of occupational injuries and obtain other relevant information. Thirty-nine participants completed the questionnaire (response rate: 83%). Participants who sustained occupational injuries throughout their careers represented 82.5%. The most injured areas were the hands, eyes, and back by 54.5%, 24.2%, and 15.2%, respectively. Approximately 11...
June 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/28638840/epidemiology-of-injuries-in-stand-up-paddle-boarding
#12
James Furness, Olayinka Olorunnife, Ben Schram, Mike Climstein, Wayne Hing
BACKGROUND: Stand-up paddle boarding (SUP) is a recreational activity and sport that has grown exponentially, with participation increasing from 1.1 million in 2010 to 2.8 million in 2014 in the United States alone. Despite this growth in participation, SUP remains underresearched with regard to injury epidemiology. PURPOSE: To investigate injury epidemiology (severity, location, type, mechanism) in SUP. STUDY DESIGN: Descriptive epidemiology study...
June 2017: Orthopaedic Journal of Sports Medicine
https://www.readbyqxmd.com/read/28637130/community-integration-and-life-satisfaction-among-individuals-with-spinal-cord-injury-living-in-the-community-after-receiving-institutional-care-in-bangladesh
#13
Nayeema Ahmed, Mohammad Morshedul Quadir, Mohammad Akhlasur Rahman, Hasanat Alamgir
PURPOSE: This study reports level of community integration and life satisfaction among individuals who sustained traumatic spinal cord injuries, received institutional rehabilitation care services, and went back to live in the community in Bangladesh. It examines the impact of type of injury, demographic characteristics, socio-economic profile, and secondary health conditions on community integration and life satisfaction and explores the association between these two measures. METHOD: Individuals with spinal cord injury were telephone interviewed by the Centre for the Rehabilitation of the Paralysed, Bangladesh from February to June of 2014...
February 7, 2017: Disability and Rehabilitation
https://www.readbyqxmd.com/read/28636132/trpc1-and-trpc3-dependent-ca-2-signaling-in-mouse-cortical-astrocytes-affects-injury-evoked-astrogliosis-in-vivo
#14
Thabet Belkacemi, Alexander Niermann, Laura Hofmann, Ulrich Wissenbach, Lutz Birnbaumer, Petra Leidinger, Christina Backes, Eckart Meese, Andreas Keller, Xianshu Bai, Anja Scheller, Frank Kirchhoff, Stephan E Philipp, Petra Weissgerber, Veit Flockerzi, Andreas Beck
Following brain injury astrocytes change into a reactive state, proliferate and grow into the site of lesion, a process called astrogliosis, initiated and regulated by changes in cytoplasmic Ca(2+) . Transient receptor potential canonical (TRPC) channels may contribute to Ca(2+) influx but their presence and possible function in astrocytes is not known. By RT-PCR and RNA sequencing we identified transcripts of Trpc1, Trpc2, Trpc3, and Trpc4 in FACS-sorted glutamate aspartate transporter (GLAST)-positive cultured mouse cortical astrocytes and subcloned full-length Trpc1 and Trpc3 cDNAs from these cells...
June 21, 2017: Glia
https://www.readbyqxmd.com/read/28630584/time-loss-injuries-in-sub-elite-and-emerging-rugby-league-players
#15
Mark Booth, Rhonda Orr
This study aimed to 1) investigate the incidence and characteristics of injuries in emerging rugby league players; and 2) explore the differences in injury incidence and characteristics between the various sub-elite competitions. An NRL emerging player development squad (n = 34) was observed from the beginning of pre-season until the finish of competition. Time-loss injury was defined as any physical pain or impairment sustained that resulted in players missing a match. Injuries were categorised according to circumstance, incidence, characteristics, playing position and competition level...
June 2017: Journal of Sports Science & Medicine
https://www.readbyqxmd.com/read/28630567/a-clinical-prospective-observational-cohort-study-on-the-prevalence-and-primary-diagnostic-accuracy-of-occult-vertebral-fractures-in-aged-women-with-acute-lower-back-pain-using-magnetic-resonance-imaging
#16
Atsushi Terakado, Sumihisa Orita, Kazuhide Inage, Go Kubota, Tomohiro Kanzaki, Hiroshi Mori, Yuji Shinohara, Junichi Nakamura, Yusuke Matsuura, Yasuchika Aoki, Takeo Furuya, Masao Koda, Seiji Ohtori
BACKGROUND: Elderly female patients complaints of acute low back pain (LBP) may involve vertebral fracture (VF), among which occult VF (OVF: early-stage VF without any morphological change) is often missed to be detected by primary X-ray examination. The current study aimed to investigate the prevalence of VF and OVF and the diagnostic accuracy of the initial X-ray in detecting OVF. METHOD: Subjects were elderly women (>70 years old) complaining of acute LBP with an accurate onset date...
2017: Pain Research & Management: the Journal of the Canadian Pain Society
https://www.readbyqxmd.com/read/28628050/arizona-hospital-discharge-and-emergency-department-database-implications-for-occupational-health-surveillance
#17
Philip Harber, Jennifer Ha, Matthew Roach
OBJECTIVES: The objective of the project was to identify trends in emergency department visits and inpatient admissions for occupational injury and disease frequency and describe the financial impact from specific clinical groups known to have occupational risk factors. METHODS: Workers compensation cases among 19 million records in the Arizona statewide hospital discharge database (HDD) were assessed for seven clinical groups from 2008 to 2014, including back, cardiac, carpal tunnel syndrome, heat-related, psychiatric, pulmonary, and trauma...
April 2017: Journal of Occupational and Environmental Medicine
https://www.readbyqxmd.com/read/28625096/surgical-technique-and-early-outcomes-of-intramedullary-nailing-of-displaced-proximal-humeral-fractures-in-an-asian-population-using-a-contemporary-straight-nail-design
#18
Toon Dong Hao, Andy Wee Teck Huat
BACKGROUND: Despite being a common orthopedic injury, the optimal management of proximal humeral fractures remains a topic of debate. Although intramedullary nails have been used to treat these fractures, several complications have been reported with older nail devices. We describe our surgical technique and aim to evaluate the early functional and radiological outcomes of displaced Neer's two- to four-part proximal humeral fractures undergoing fixation with a contemporary straight intramedullary nail...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28622786/dairy-cow-disability-weights
#19
Craig S McConnel, Ashleigh A McNeil, Joleen C Hadrich, Jason E Lombard, Franklyn B Garry, Jane Heller
Over the past 175 years, data related to human disease and death have progressed to a summary measure of population health, the Disability-Adjusted Life Year (DALY). As dairies have intensified there has been no equivalent measure of the impact of disease on the productive life and well-being of animals. The development of a disease-adjusted metric requires a consistent set of disability weights that reflect the relative severity of important diseases. The objective of this study was to use an international survey of dairy authorities to derive disability weights for primary disease categories recorded on dairies...
August 1, 2017: Preventive Veterinary Medicine
https://www.readbyqxmd.com/read/28621630/evaluation-of-surgical-treatment-for-neuropathic-pain-from-neuroma-in-patients-with-injured-peripheral-nerves
#20
Valérie Decrouy-Duruz, Thierry Christen, Wassim Raffoul
OBJECTIVE Chronic neuropathic pain after peripheral nerve injury is a major clinical problem. Its management is difficult, and therapeutic approaches vary and include oral medication, neurostimulation, and surgery. The aim of this study was to assess the adequacy of surgical nerve revision in a large series of patients with long-term follow-up. METHODS The authors reviewed the charts of 231 patients (335 nerve injuries) who experienced neuropathic pain after peripheral nerve injury and underwent surgery for nerve revision at the authors' institution between 1997 and 2012...
June 16, 2017: Journal of Neurosurgery
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