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https://www.readbyqxmd.com/read/29909584/comparison-of-clinical-results-between-novel-percutaneous-pedicle-screw-and-traditional-open-pedicle-screw-fixation-for-thoracolumbar-fractures-without-neurological-deficit
#1
Ming Yang, Qinpeng Zhao, Dingjun Hao, Zhen Chang, Shichang Liu, Xinhua Yin
OBJECTIVES: To compare the efficacy and safety of novel percutaneous minimally invasive pedicle screw fixation and traditional open surgery for thoracolumbar fractures without neurological deficit. METHODS: Sixty adult patients with single thoracolumbar fracture between June 2014 and June 2016 were recruited in this study, randomly divided into open fixation group (group A) or minimally invasive percutaneous fixation group (group B). Clinical and surgical evaluation including surgery time, blood losses, radiation times, hospital stay, and complication were performed...
June 16, 2018: International Orthopaedics
https://www.readbyqxmd.com/read/29909460/modulation-of-brain-ace-and-ace2-may-be-a-promising-protective-strategy-against-cerebral-ischemia-reperfusion-injury-an-experimental-trial-in-rats
#2
Maha Mohammed Abdel-Fattah, Basim Anwar Shehata Messiha, Ahmed Mohamed Mansour
The brain renin-angiotensin system (RAS) is considered a crucial regulator for physiological homeostasis and disease progression. We evaluated the protective effects of the angiotensin receptor blocker (ARB) telmisartan and the angiotensin-converting enzyme 2 (ACE2) activator xanthenone on experimental cerebral ischemia/reperfusion (I/R) injury. Rats were divided into a sham control, a cerebral I/R control, a standard treatment (nimodipine, 10 mg/kg/day, 15 days, p.o.), three telmisartan treatments (1, 3, and 10 mg/kg/day, 15 days, p...
June 17, 2018: Naunyn-Schmiedeberg's Archives of Pharmacology
https://www.readbyqxmd.com/read/29906811/comparison-of-hand-sewn-versus-coupled-venous-anastomoses-in-traumatic-lower-extremity-reconstruction
#3
John T Stranix, William J Rifkin, Z-Hye Lee, Lavinia Anzai, Adam Jacoby, Daniel J Ceradini, Vishal Thanik, Pierre B Saadeh, Jamie P Levine
BACKGROUND:  Microvascular reconstruction of the lower extremity has the highest reported complication and flap failure rates of any anatomical region. Despite widespread adoption of the mechanical anastomotic venous coupler and encouraging results in other anatomical regions, there are limited reports examining its use in the lower extremity. This study compares outcomes between coupled and hand-sewn venous anastomoses in traumatic lower extremity reconstruction. METHODS:  Retrospective review of our institutional flap registry from 1979 to 2016 identified soft tissue free flaps performed for the reconstruction of Gustilo type IIIB/IIIC open tibial fractures...
June 15, 2018: Journal of Reconstructive Microsurgery
https://www.readbyqxmd.com/read/29905767/the-multisystem-effects-of-simulated-agricultural-whole-body-vibration-on-acute-sensorimotor-physical-and-cognitive-performance
#4
Marcus Yung, Liana M Tennant, Stephan Milosavljevic, Catherine Trask
Background: Exposure to whole body vibration (WBV) is common in construction, agriculture, mining, and transportation. There is strong epidemiological evidence linking WBV with adverse health outcomes in the long-term, including low back pain. Fortunately, WBV exposure guidelines to prevent long-term musculoskeletal disorders and discomfort exist. In the shorter-term, it has been speculated that occupational levels of WBV may lead to increased risk of vehicle accidents and falls during egress; however, the acute effects of different vibration intensities remain poorly understood and it is uncertain whether established standards protect the worker from injurious short-term effects...
June 14, 2018: Annals of Work Exposures and Health
https://www.readbyqxmd.com/read/29905054/-research-of-acellular-xenogeneic-nerve-combined-with-adipose-derived-stem-cells-and-platelet-rich-plasma-in-repair-of-rabbit-facial-nerve-injury
#5
Yanna Sun, Rongming Zhang, Xu Mao, Mengshu Zhang
Objective: To investigate the early effects of acellular xenogeneic nerve combined with adipose-derived stem cells (ADSCs) and platelet rich plasma (PRP) in repairing facial nerve injury in rabbits. Methods: The bilateral sciatic nerves of 15 3-month-old male Sprague-Dawley rats were harvested and decellularized as xenografts. The allogeneic ADSCs were extracted from the neck and back fat pad of healthy adult New Zealand rabbits with a method of digestion by collagenase type Ⅰ and the autologous PRP was prepared by two step centrifugation...
June 1, 2018: Chinese Journal of Reparative and Reconstructive Surgery
https://www.readbyqxmd.com/read/29904614/treatment-of-arrow-wounds-a-review
#6
REVIEW
Rafik Shereen, Rod J Oskouian, Marios Loukas, R Shane Tubbs
The arrow is one of the oldest weapons invented that has ties back to ancient civilization. With the advancement of modern weaponry, literature concerning the management of this traumatic wound has dwindled.  However, there are older written accounts that have led to our understanding of how we manage injuries inflicted by the arrow. One of the more comprehensive accounts was produced in the 19th century by a United States (US) Lieutenant Colonel named JH Bill. Recent cases in forensic pathology, as well as instances of trauma concerning arrowhead injuries, have documented a lack of comprehensive literature for the management of such injuries...
April 13, 2018: Curēus
https://www.readbyqxmd.com/read/29900000/staphylococcus-associated-glomerulonephritis-mimicking-henoch-sch%C3%A3-nlein-purpura-and-cryoglobulinemic-vasculitis-in-a-patient-with-an-epidural-abscess-a-case-report-and-brief-review-of-the-literature
#7
Tahrin Mahmood, Robert Puckrin, Linda Sugar, David Naimark
Rationale: Staphylococcus-associated glomerulonephritis (SAGN) is a rare immune complex-mediated glomerulonephritis associated with active Staphylococcus infection. We report a case illustrating the importance of clinical history and kidney biopsy findings in establishing the correct diagnosis. Presenting concerns of the patient: We report the case of a 64-year-old man with alcohol-associated cirrhosis, type 2 diabetes mellitus, and hypertension who presented to hospital with lower back and abdominal pain, rectal bleeding, a purpuric lower extremity rash, and oliguric acute kidney injury with microscopic hematuria and nephrotic-range proteinuria...
2018: Canadian Journal of Kidney Health and Disease
https://www.readbyqxmd.com/read/29898866/back-to-the-future-the-cecil-culp-technique-for-salvage-penile-reconstructive-procedures
#8
D A Weiss, C J Long, J R Frazier, A R Shukla, A K Srinivasan, T F Kolon, H DiCarlo, J P Gearhart, D A Canning
INTRODUCTION: Re-operative penile reconstruction is challenging and requires tension-free skin closure. The repair popularized by Cecil and Culp in the 1940s, using the scrotum to provide a temporary vascularized bed for complex hypospadias repairs, fell out of favor due to temporal trends towards single-stage repairs and concern for utilizing hair-bearing skin on the penile shaft. OBJECTIVE: It was hypothesized that a modified Cecil-Culp (CC) concept of penile scrotalization, leaving the penis attached to the scrotum for 1 year rather than 6 weeks as originally described, improves outcomes with this reconstruction for ventral skin deficiency or poor vascular support...
May 30, 2018: Journal of Pediatric Urology
https://www.readbyqxmd.com/read/29897279/work-related-injury-and-management-strategies-among-certified-athletic-trainers
#9
Kristen L Kucera, Hester J Lipscomb, Karen G Roos, John M Dement, Jennifer M Hootman
CONTEXT:   Health care workers have high rates of musculoskeletal injuries, but many of these injuries go unreported to workers' compensation and national surveillance systems. Little is known regarding the work-related injuries of certified athletic trainers (ATs). OBJECTIVE:   To determine the 12-month incidence and prevalence of work-related injuries and describe injury-reporting and -management strategies. DESIGN:   Cross-sectional study...
June 13, 2018: Journal of Athletic Training
https://www.readbyqxmd.com/read/29896919/priming-and-de-priming-of-neutrophil-responses-in-vitro-and-in-vivo
#10
REVIEW
Katja L Vogt, Charlotte Summers, Edwin R Chilvers, Alison M Condliffe
The activation status of neutrophils can cycle from basal through primed to fully activated ('green-amber-red'), and at least in vitro, primed cells can spontaneously revert to a near basal phenotype. This broad range of neutrophil responsiveness confers extensive functional flexibility, allowing neutrophils to respond rapidly and appropriately to varied and evolving threats throughout the body. Primed and activated cells display dramatically enhanced bactericidal capacity (including augmented respiratory burst activity, degranulation and longevity), but this enhancement also confers the capacity for significant unintended tissue injury...
June 13, 2018: European Journal of Clinical Investigation
https://www.readbyqxmd.com/read/29895865/a-potential-new-role-for-myofibroblasts-in-remodeling-of-sub-rupture-fatigue-tendon-injuries-by-exercise
#11
Rebecca Bell, N Remi Gendron, Matthew Anderson, Evan L Flatow, Nelly Andarawis-Puri
Tendons are ineffective at repairing sub-rupture fatigue injuries. Accordingly, we evaluated whether an exercise protocol that we have previously found to decrease structural damage kinks in fatigue damaged tendons, leads to improvement in mechanical properties. We hypothesized that exercise that promotes repair of fatigue damage will decrease apoptosis and increase the population of myofibroblasts. Rat patellar tendons underwent in vivo fatigue loading for 500 or 7200 cycles. Animals resumed cage activity for 2-weeks, then either remained cage active or began treadmill running until sacrifice at 4- or 10-weeks post-fatigue loading...
June 12, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29895403/effect-of-tadalafil-on-reduction-of-necrosis-in-the-ischemic-zone-in-a-rat-comb-burn-model
#12
Adam J Singer, Henry Towery, Steve A McClain
OBJECTIVES: A major goal of burn management is to reduce the progression of necrosis in the zone of ischemia surrounding the central zone of necrosis. A rat comb burn model is often used to assess the progression of necrosis in the zone of ischemia. We compared various combinations of naproxen [NPX], N-acetyl cysteine [NAC], and tadalafil [TD] (a phosphodiesterase-5 inhibitor used as a vasodilator to treat erectile dysfunction) in a rat comb burn model to determine their effects on injury progression...
June 9, 2018: Burns: Journal of the International Society for Burn Injuries
https://www.readbyqxmd.com/read/29894812/why-are-there-no-drugs-indicated-for-sciatica-the-most-common-chronic-neuropathic-syndrome-of-all
#13
REVIEW
John D Markman, Ralf Baron, Jennifer S Gewandter
Here, we examine the stark contrast between the successes and failures of the clinical development of analgesics for different types of chronic low back pain (CLBP) syndrome over the past three decades. Multiple drugs with differing mechanisms of action have been developed for nonspecific axial-predominant low back syndromes and yet not a single therapy is indicated for any neuropathic low back pain syndrome (e.g., sciatica). Clinician findings have informed the entry criteria for neuropathic low back pain clinical trials, whereas entry criteria of axial CLBP trials have prioritized only patient reports of pain...
June 9, 2018: Drug Discovery Today
https://www.readbyqxmd.com/read/29890263/long-term-outcome-of-treatment-of-vertebral-body-hemangiomas-with-direct-ethanol-injection-and-short-segment-stabilization
#14
P Sarat Chandra, Pankaj Singh, Rajender K, Deepak Agarwal, Vivek Tandon, S S Kale, Chitra Sarkar
BACKGROUND: Vertebral body (VH) hemangiomas with myelopathy are difficult to manage. OBJECTIVE: To evaluate the role of intra-operative ethanol embolization, surgical decompression and instrumented short segment fusion in VH with myelopathy and long-term outcome (>24 months). METHODS: Prospective study: Symptomatic VH with cord compression with myelopathy. Excluded: pathological fractures, and/or deformity or multi-level pathologies. Surgery consisted of intra-operative bilateral pedicular absolute alcohol (<1% hydrated ethyl alcohol) injection, laminectomy and cord decompression at the level of pathology followed by a short segment instrumented fusion using pedicle screws...
June 8, 2018: Spine Journal: Official Journal of the North American Spine Society
https://www.readbyqxmd.com/read/29889150/core-and-back-rehabilitation-for-high-speed-rotation-sports-highlight-on-lacrosse
#15
Heather K Vincent, Kevin R Vincent
Lacrosse is a fast-paced game that incorporates elements from multiple sports, such as soccer, basketball, baseball, tennis, and hockey. The sport involves rapid changes of direction, endurance, sprinting, physical contact, rotational movement, passing, and shooting. Passing and shooting are further complicated by having a weighted object (ball) at the end of a long moment arm (crosse) which places increased stress on the body segments. Thus, it is important to properly prepare for sport participation by improving strength, endurance, and dynamic stability of the postural and core stability muscles...
June 2018: Current Sports Medicine Reports
https://www.readbyqxmd.com/read/29889057/effects-of-assisted-sit-up-exercise-compared-to-core-stabilization-exercise-on-patients-with-non-specific-low-back-pain-a-randomized-controlled-trial
#16
Cho-Rong Bae, Yan Jin, Bum-Chul Yoon, Nack-Hwan Kim, Kun-Woo Park, Sang-Heon Lee
BACKGROUND: Traditional sit-up exercise is a simple method to strengthen core muscles. However, it can increase the potential of lumbar spine injury during the bending process. OBJECTIVE: To evaluate the effect of assisted sit-up exercise (SUE) using a new training device, HubEX-LEX, on strengthening core muscles and improving non-specific low back pain (NSLBP) compared to conventional core stabilization exercise (CSE). METHODS: Subjects with chronic NSLBP were randomly divided into two groups: SUE (n= 18) or CSE (n= 18)...
May 26, 2018: Journal of Back and Musculoskeletal Rehabilitation
https://www.readbyqxmd.com/read/29886318/prevention-of-shoulder-dystocia-a-randomized-controlled-trial-to-evaluate-an-obstetric-maneuver
#17
Olivier Poujade, Elie Azria, Pierre-François Ceccaldi, Carine Davitian, Carine Khater, Paul Chatel, Emilie Pernin, Nizar Aflak, Martin Koskas, Agnès Bourgeois-Moine, Laurence Hamou-Plotkine, Morgane Valentin, Jean-Paul Renner, Carine Roy, Candice Estellat, Dominique Luton
OBJECTIVE: Shoulder dystocia is a major obstetric emergency defined as a failure of delivery of the fetal shoulder(s). This study evaluated whether an obstetric maneuver, the push back maneuver performed gently on the fetal head during delivery, could reduce the risk of shoulder dystocia. STUDY DESIGN: We performed a multicenter, randomized, single-blind trial to compare the push back maneuver with usual care in parturient women at term. The primary outcome, shoulder dystocia, was considered to have occurred if, after delivery of the fetal head, any additional obstetric maneuver, beginning with the McRoberts maneuver, other than gentle downward traction and episiotomy was required...
June 4, 2018: European Journal of Obstetrics, Gynecology, and Reproductive Biology
https://www.readbyqxmd.com/read/29884165/the-effectiveness-of-interventions-designed-to-increase-the-uptake-of-clinical-practice-guidelines-and-best-practices-among-musculoskeletal-professionals-a-systematic-review
#18
Fadi M Al Zoubi, Anita Menon, Nancy E Mayo, André E Bussières
BACKGROUND: The objective of this systematic review was to summarize and evaluate evidence about the effectiveness of knowledge translation (KT) interventions to improve the uptake and application of clinical practice guidelines and best practices for a wide range of musculoskeletal (MSK) disorders and health care professionals. METHODS: A search for relevant randomized controlled trials (RCTs) published in English was conducted in MEDLINE (Ovid interface), EMBASE, CINAHL, and CENTRAL (Cochrane library)...
June 8, 2018: BMC Health Services Research
https://www.readbyqxmd.com/read/29879068/delayed-hydronephrosis-due-to-retroperitoneal-hematoma-after-a-seatbelt-injury-a-case-report
#19
Tetsuya Yumoto, Yoshitaka Kondo, Kento Kumon, Yoshihisa Masaoka, Takao Hiraki, Taihei Yamada, Hiromichi Naito, Atsunori Nakao
RATIONALE: Hydronephrosis caused by retroperitoneal hematoma after a seatbelt injury is a unique clinical entity. PATIENT CONCERNS: A 21-year-old man, who had been wearing a seatbelt, was brought to our hospital after a motor vehicle collision, complaining of abdominal pain. Computed tomography (CT) revealed retroperitoneal hematoma in the upper pelvic region. Since he was hemodynamically stable throughout admission, he was managed conservatively. Seventeen days after initial discharge, the patient revisited our emergency department due to right back pain...
June 2018: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29877672/how-effective-is-the-integration-of-sport-and-exercise-medicine-in-the-english-national-health-service-for-sport-related-injury-treatment-and-health-management
#20
Emma Pullen, Dominic Malcolm, Patrick Wheeler
BACKGROUND: Regular participation in sport, exercise and physical activity is associated with positive health outcomes and form a mainstay of British public health policies. However, regular participation in sport and exercise can result in sport related injury (SRI) which, in turn, is a key cause of exercise cessation. The integration of Sport and Exercise Medicine (SEM) in the English National Health Service (NHS) aims to provide a specialist service for public populations and thus reduce the impact of SRI on exercise cessation and associated negative health outcomes...
June 7, 2018: Journal of Sports Medicine and Physical Fitness
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