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LAM experienced

Jan-Marie Kozicky, Alexander McGirr, David J Bond, Marjorie Gonzalez, Leonardo E Silveira, Kamyar Keramatian, Ivan J Torres, Raymond W Lam, Lakshmi N Yatham
OBJECTIVES: Bipolar I disorder (BD-I) is associated with gray matter volume (GMV) alterations in neural regions important for emotional regulation. Reductions found in patients with multiple episodes are not seen at illness onset, suggesting that changes occur with illness progression, although no prospective studies to date have examined this. In the present study, we assessed GMV at baseline and one year following a first manic episode, examining the impact of episode recurrence on the trajectory of change...
September 2016: Bipolar Disorders
IJsbrand T Klip, Adriaan A Voors, Dorine W Swinkels, Stephan J L Bakker, Jenny E Kootstra-Ros, Carolyn S Lam, Pim van der Harst, Dirk J van Veldhuisen, Peter van der Meer
AIMS: Heart failure (HF) is a common manifestation of patients with primary and secondary causes of iron overload, whereas in patients with established HF iron deficiency impairs outcome. Whether iron stores, either depleted or in overload, amplify the risk for new-onset HF among healthy individuals is unknown. The present study aimed to assess whether markers of iron status or the iron-regulatory hormone hepcidin are associated with new-onset HF or cardiovascular (CV) events in the general population...
October 19, 2016: European Journal of Heart Failure
Katherine Clark, Lawrence T Lam, Nicholas J Talley, Jane L Phillips, David C Currow
OBJECTIVE: The aim of this work was to investigate whether variables identified as likely to impact the experience of constipation in other clinical settings similarly affected the experiences of constipated palliative care patients. BACKGROUND: The majority of palliative care patients with cancer are likely to be bothered by constipation symptoms at some point in their disease trajectory. Despite this, it remains unclear as to which factors predict more severe problems...
October 18, 2016: Journal of Palliative Medicine
Diogo F Almeida, Rui B Ruben, João Folgado, Paulo R Fernandes, Emmanuel Audenaert, Benedict Verhegghe, Matthieu De Beule
Femur segmentation can be an important tool in orthopedic surgical planning. However, in order to overcome the need of an experienced user with extensive knowledge on the techniques, segmentation should be fully automatic. In this paper a new fully automatic femur segmentation method for CT images is presented. This method is also able to define automatically the medullary canal and performs well even in low resolution CT scans. Fully automatic femoral segmentation was performed adapting a template mesh of the femoral volume to medical images...
October 14, 2016: Medical Engineering & Physics
Baldwin Yeung, Philip Chiu, Anthony Teoh, Linfu Zheng, Shannon Chan, Kelvin Lam, Raymond Tang, Enders K W Ng
Background and study aims: Submucosal tunnelling endoscopic resection (STER) is a novel endoscopic technique to remove submucosal tumour (SMT). We propose a novel, low cost simulator for training of techniques for STER. Patients and methods: The model consisted of an ex-planted porcine oesophagus, stomach and duodenum with marbles embedded surgically in the submucosal plane. Two expert endoscopists with experience in submucosal tunnelling and 5 board-certified endoscopists with no experience in submucosal tunnelling were recruited...
October 2016: Endoscopy International Open
Ilaria Galizia, Lucio Oldani, Karine Macritchie, Erica Amari, Dominic Dougall, Tessa N Jones, Raymond W Lam, Guido Jacopo Massei, Lakshmi N Yatham, Allan H Young
BACKGROUND: Depression is a recurrent illness with high rates of chronicity, treatment-resistance and significant economic impact. There is evidence in the literature that S-adenosyl methionine (SAMe), a naturally occurring compound in the human body, has antidepressant efficacy. This product may be an important addition to the armamentarium of antidepressant agents. OBJECTIVES: To assess the effects of SAMe in comparison with placebo or antidepressants for the treatment of depression in adults...
October 10, 2016: Cochrane Database of Systematic Reviews
Jenny X Chen, Blake C Alkire, Allen C Lam, William T Curry, Eric H Holbrook
Objectives While bacterial meningitis is a concerning complication after endoscopic skull base surgery, the diagnosis can be made without consideration for aseptic meningitis. This article aims to (1) present a patient with recurrent craniopharyngioma and multiple postoperative episodes of aseptic meningitis and (2) discuss the diagnosis and management of aseptic meningitis. Design Case report and literature review. Results A 65-year-old female patient with a symptomatic craniopharyngioma underwent transsphenoidal resection...
October 2016: Journal of Neurological Surgery Reports
Kerry A Sherman, Laura-Kate E Shaw, Caleb J Winch, Diana Harcourt, John Boyages, Linda D Cameron, Paul Brown, Thomas Lam, Elisabeth Elder, James French, Andrew Spillane
BACKGROUND: Deciding whether or not to have breast reconstruction following breast cancer diagnosis is a complex decision process. This randomized controlled trial assessed the impact of an online decision aid [Breast RECONstruction Decision Aid (BRECONDA)] on breast reconstruction decision-making. METHODS: Women (n = 222) diagnosed with breast cancer or ductal carcinoma in situ, and eligible for reconstruction following mastectomy, completed an online baseline questionnaire...
October 2016: Plastic and Reconstructive Surgery
Lin Xu, Tai Hing Lam, Chao Qiang Jiang, Wei Sen Zhang, Ya Li Jin, Tong Zhu, Hubert K B Lam, Catherine Mary Schooling, Peymane Adab, G Neil Thomas, Kar Keung Cheng
OBJECTIVE: To examine the changes in body mass index (BMI) and waist circumference (WC) in Guangzhou, South China, which is probably experiencing the most rapid economic transition in history. METHODS: In this study, 17,786 Chinese aged 50+ years were recruited from 2003 to 2008 and followed up until 2012. BMI and WC were measured at two time points. RESULTS: During the mean follow-up of 3.6 years (median = 3, interquartile = 1), age-adjusted mean BMI increased only slightly...
October 2016: Obesity
Brandi Cole, Kristen Twibill, Patrick Lam, Lisa Hackett, George Ac Murrell
BACKGROUND: This cross-sectional analytic diagnostic accuracy study was designed to compare the accuracy of ultrasound performed by general sonographers in local radiology practices with ultrasound performed by an experienced musculoskeletal sonographer for the detection of rotator cuff tears. METHODS: In total, 238 patients undergoing arthroscopy who had previously had an ultrasound performed by both a general sonographer and a specialist musculoskeletal sonographer made up the study cohort...
October 2016: Shoulder & Elbow
Christopher J DiMaio, Jennifer M Kolb, Petros C Benias, Hiral Shah, Shashin Shah, Oleh Haluszka, Jennifer Maranki, Kaveh Sharzehi, Eric Lam, Stuart R Gordon, Sarah M Hyder, Pavlos Z Kaimakliotis, Satya B Allaparthi, Frank G Gress, Amrita Sethi, Ashish R Shah, Jose Nieto, Vivek Kaul, Shivangi Kothari, Truptesh H Kothari, Sammy Ho, Manhal J Izzy, Neil R Sharma, Rabindra R Watson, V Raman Muthusamy, Douglas K Pleskow, Tyler M Berzin, Mandeep Sawhney, Emad Aljahdi, Marvin Ryou, Clarence K Wong, Parantap Gupta, Dennis Yang, Susana Gonzalez, Douglas G Adler
BACKGROUND AND AIMS: The ability to safely and effectively obtain sufficient tissue for pathologic evaluation by using endoscopic ultrasound (EUS) guidance remains a challenge. Novel designs in EUS needles may provide for improved ability to obtain such core biopsies. The aim of this study was to evaluate the diagnostic yield of core biopsy specimens obtained using a novel EUS needle specifically designed to obtain core biopsies. PATIENTS AND METHODS: Multicenter retrospective review of all EUS-guided fine-needle biopsies obtained using a novel biopsy needle (SharkCore FNB needle, Medtronic, Dublin, Ireland)...
September 2016: Endoscopy International Open
Amy Tyberg, Jose Nieto, Sanjay Salgado, Kristen Weaver, Prashant Kedia, Reem Z Sharaiha, Monica Gaidhane, Michel Kahaleh
Background/Aims: Performing endoscopic retrograde cholangiopancreatography (ERCP) in patients who have undergone Rouxen-Y gastric bypass (RYGB) is challenging. Standard ERCP and enteroscopy-assisted ERCP are associated with limited success rates. Laparoscopy- or laparotomy-assisted ERCP yields improved efficacy rates, but with higher complication rates and costs. We present the first multicenter experience regarding the efficacy and safety of endoscopic ultrasound (EUS)-directed transgastric ERCP (EDGE) or EUS...
September 19, 2016: Clinical Endoscopy
Linda P Juang, Ursula Moffitt, Su Yeong Kim, Richard M Lee, José Angel Soto, Eric Hurley, Robert S Weisskirch, Shelley A Blozis, Linda G Castillo, Que-Lam Huynh, Susan Krauss Whitborne
OBJECTIVE: We examined whether two key emotion regulation strategies, cognitive reappraisal and expressive suppression, moderated the relations between discrimination (i.e., foreigner objectification and general denigration) and adjustment. METHODS: Participants were U.S. Latino/a and Asian-heritage college students (N = 1,279, 67% female, 72% U.S. born) from the Multi-Site University Study of Identity and Culture (MUSIC). Students completed online self-report surveys in 2009...
September 3, 2016: Journal of Adolescence
Armin Ariana, Moein Amin, Sahar Pakneshan, Elliot Dolan-Evans, Alfred K Lam
Dental students require a basic ability to explain and apply general principles of pathology to systemic, dental, and oral pathology. Although there have been recent advances in electronic and online resources, the academic effectiveness of using self-directed e-learning tools in pathology courses for dental students is unclear. The aim of this study was to determine if blended learning combining e-learning with traditional learning methods of lectures and tutorials would improve students' scores and satisfaction over those who experienced traditional learning alone...
September 2016: Journal of Dental Education
Thomas R Lucena, Patrick H Lam, Neal L Millar, George Ac Murrell
BACKGROUND: The present study aimed to determine how repair technique influenced structural and clinical outcomes at 5 years post-surgery. METHODS: Three cohorts of patients had repair of a symptomatic rotator cuff tear using (i) an open double-row mattress repair technique (n = 25); (ii) arthroscopic single-row simple suture knotted technique (n = 25); or (iii) arthroscopic single-row inverted mattress knotless technique (n = 36) by one surgeon. Standardized patient- and examiner-determined outcomes were obtained pre-operatively and postoperatively with a validated protocol, ultrasound were also performed at the same time...
October 2015: Shoulder & Elbow
Soomi Lee, Kelly D Davis, Claudia Neuendorf, Alicia Grandey, Chun Bun Lam, David M Almeida
PURPOSE: Building on the Conservation of Resources theory, this paper examined the unique and interactive associations of negative and positive work-to-family spillover (NWFS and PWFS, respectively) at the individual and organizational level with hotel managers' work exhaustion and satisfaction, beyond job demands and supervisors' leadership style. DESIGN/METHODOLOGY/APPROACH: Guided by the levels of analysis framework, we first tested the unique associations of NWFS and PWFS with emotional exhaustion and job satisfaction at the individual level (571 hotel managers), beyond job demands supervisors' leadership style...
2016: Frontiers in Psychology
V Khalil, J M deClifford, S Lam, A Subramaniam
WHAT IS KNOWN AND OBJECTIVE: Medication errors on admission can persist throughout the episode of care and on to discharge leading to inappropriate management that can compromise patients' care. The aim of the study was to develop, implement and evaluate the role of pharmacist-led medication reconciliation and charting service for patients admitted to an Acute Assessment and Admission Unit via the Emergency Department in an electronic medication management environment at a metropolitan Australian hospital...
August 31, 2016: Journal of Clinical Pharmacy and Therapeutics
Elisa K Tong, Tung T Nguyen, Penny Lo, Susan L Stewart, Ginny L Gildengorin, Janice Y Tsoh, Angela M Jo, Marjorie L Kagawa-Singer, Angela U Sy, Charlene Cuaresma, Hy T Lam, Ching Wong, Mi T Tran, Moon S Chen
BACKGROUND: Asian Americans have lower colorectal cancer (CRC) screening rates than non-Hispanic white individuals. Hmong Americans have limited socioeconomic resources and literacy. The current randomized controlled trial was conducted to determine whether bilingual/bicultural lay health educator (LHE) education could increase CRC screening among Hmong Americans. METHODS: A cluster randomized controlled trial was conducted among Hmong Americans in Sacramento, California...
August 26, 2016: Cancer
Helen H Zhao, Scott E Seibert, M Susan Taylor, Cynthia Lee, Wing Lam
Leader succession often occurs during organizational change processes, but the implications of leader succession, in terms of reactions to the change, rarely have been investigated. Employee attitudes and behaviors during organizational change may be influenced jointly by a former leader who recently has transitioned out of the team and the new leader who recently has transitioned into it. We predict an interaction between former and new leaders' transformational leadership on employees' behavioral resistance to and support for change...
August 18, 2016: Journal of Applied Psychology
M Brahmania, W P Brouwer, T Hansen, T Mazzulli, J Feld, D Wong, M Kowgier, H L A Janssen
The clinical relevance of viral blipping during nucleos (t) ide analogue (NA) treatment is unclear in chronic hepatitis B (CHB). We investigated the prevalence, risk factors and clinical outcomes for those with viral blipping during NA treatment. A retrospective cohort study investigated consecutively treated CHB patients from May 2008 to February 2015 on the NAs such as entecavir (ETV), tenofovir (TDF) and lamivudine (LAM). Included patients were previously treatment naive. Viral blipping was defined as serum HBV DNA >20 IU/mL on one occasion, and not >200 IU/mL, with subsequent measurement returning to undetectable levels, that is <20 IU/mL...
August 9, 2016: Journal of Viral Hepatitis
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