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https://www.readbyqxmd.com/read/29378606/treponema-pallidum-immunohistochemistry-is-positive-in-human-intestinal-spirochetosis
#1
Rondell P Graham, Bita V Naini, Sejal S Shah, Christina A Arnold, Rajesh Kannangai, Michael S Torbenson, Dora M Lam-Himlin
BACKGROUND: Human intestinal spirochetosis (IS) has been recognized for decades, but whether it represents commensalism or a pathogenic process remains controversial. IS is diagnosed on routine stains with confirmation by silver stains but these stains are labor intensive and slow to read. We evaluated the Treponema pallidum immunostain as a diagnostic adjunct for IS. METHODS: We retrieved biopsies from 33 patients with IS for this study. Each case was tested by Warthin-Starry (WS) and T...
January 22, 2018: Diagnostic Pathology
https://www.readbyqxmd.com/read/29370965/preventing-brachial-plexus-injury-during-shoulder-surgery-a-real-time-cadaveric-study
#2
Andrew W Kam, Patrick H Lam, Pieter S W A Haen, Martin Tan, Aminudin Shamsudin, George A C Murrell
BACKGROUND: Brachial plexopathy is not uncommon after shoulder surgery. Although thought to be due to stretch neuropathy, its etiology is poorly understood. This study aimed to identify arm positions and maneuvers that may risk causing brachial plexopathy during shoulder arthroplasty. METHODS: Tensions in the cords of the brachial plexuses of 6 human cadaveric upper limbs were measured using load cells while each limb was placed in different arm positions and while they underwent shoulder hemiarthroplasty and revision reverse arthroplasty...
January 19, 2018: Journal of Shoulder and Elbow Surgery
https://www.readbyqxmd.com/read/29348085/toxic-effect-of-common-poisonous-plants-of-district-bannu-khyber-pakhtunkhwa-pakistan
#3
Rehman Ullah Khan, Sultan Mehmood, Saad Ullah Khan
The present paper was a part of Ph.D research work, conducted during the year 2014, in which 87 poisonous plants belonging to 54 genera, were collected, documented and preserved in the herbarium of Bannu, Department of Botany UST, Bannu Khyber Pakhtunkwa Pakistan. The plants were identified botanically, arranged alphabetically along with their Latin name, family name, common name, poisonous parts, toxicity, affects, toxin and their effects. Aim of the study was to induce awareness in the local people of district Bannu about the poisonous effects of the commonly used plants...
January 2018: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29329350/incidence-and-risk-factors-for-postoperative-lingual-neuropraxia-following-airway-instrumentation-a-retrospective-matched-case-control-study
#4
Yi-Kai Su, Jen-Hung Wang, Shiu-Ying Hsieh, Xiu-Zhu Liu, Chen-Fuh Lam, Shian-Che Huang
BACKGROUND: Lingual nerve injury or neuropraxia is a rare but potentially serious perioperative complication following airway instrumentation during general anesthesia. This study explored the the incidence and perioperative risk factors for lingual nerve injury in patients receiving laryngeal mask (LMA) or endotracheal (ETGA) general anesthesia in a single center experience. METHODS AND RESULTS: All surgical patients in our hospital who received LMA or ETGA from 2009 to 2013 were included, and potential perioperative risk factors were compared...
2018: PloS One
https://www.readbyqxmd.com/read/29329305/evaluating-the-efficacy-of-switching-from-lamivudine-plus-adefovir-to-tenofovir-disoproxil-fumarate-monotherapy-in-lamivudine-resistant-stable-hepatitis-b-patients
#5
Heon Ju Lee, Sang Jin Kim, Young Oh Kweon, Soo Young Park, Jeong Heo, Hyun Young Woo, Jae Seok Hwang, Woo Jin Chung, Chang Hyeong Lee, Byung Seok Kim, Jeong Ill Suh, Won Young Tak, Byoung Kuk Jang
BACKGROUND: The efficacy of switching to tenofovir disoproxil fumarate (TDF) monotherapy from lamivudine (LAM) plus adefovir dipivoxil (ADV) combination therapy (stable switching) in patients with LAM-resistant chronic hepatitis B (CHB) and undetectable hepatitis B virus (HBV) DNA is not clear. METHODS: In this non-inferiority trial, patients with LAM-resistant CHB and undetectable serum HBV DNA (<20 IU/mL) for >6 months after initiating LAM+ADV combination therapy were randomized (1:2) either to continue the combination therapy (LAM+ADV group, n = 58) or switched to TDF monotherapy (TDF group, n = 111)...
2018: PloS One
https://www.readbyqxmd.com/read/29315963/distinct-and-heterogeneous-trajectories-of-self-perceived-cognitive-impairment-among-asian-breast-cancer-survivors
#6
Terence Ng, Sreemanee Raaj Dorajoo, Yin Ting Cheung, Yick Ching Lam, Hui Ling Yeo, Maung Shwe, Yan Xiang Gan, Koon Mian Foo, Wei-Jen Kiley Loh, Si-Lin Koo, Amit Jain, Guek Eng Lee, Rebecca Dent, Yoon Sim Yap, Raymond Ng, Alexandre Chan
OBJECTIVES: Currently, there are no studies that have established the self-perceived cognitive trajectories experienced by breast cancer patients (BCPs) post-chemotherapy. Therefore, we characterized the long-term trajectory of self-perceived cognitive function among Asian early-stage BCPs using the minimal clinically important difference (MCID) of a subjective measure of cognitive function. METHODS: Early-stage BCPs who received chemotherapy were recruited and assessed at four time points: Before chemotherapy initiation (T1), 6 weeks post-chemotherapy initiation (T2), 12 weeks post-chemotherapy initiation (T3), and 15-months post-chemotherapy initiation (T4)...
January 9, 2018: Psycho-oncology
https://www.readbyqxmd.com/read/29309367/intratumoral-injection-of-radioactive-holmium-166-microspheres-in-recurrent-head-and-neck-squamous-cell-carcinoma-preliminary-results-of-first-use
#7
Robbert C Bakker, Robert J J van Es, Antoine J W P Rosenberg, Sebastiaan A van Nimwegen, Remco Bastiaannet, Hugo W A M de Jong, Johannes F W Nijsen, Marnix G E H Lam
BACKGROUND: Limited treatment options exist for patients with locoregional recurrences of head and neck squamous cell carcinoma (HNSCC). In the palliative setting, a single session, minimally invasive, and relatively safe therapy is desirable. This case series illustrates the feasibility of a direct intratumoral injection of radioactive holmium-166 microspheres (HoMS) in patients as a palliative treatment for recurrent HNSCC. PATIENTS AND METHODS: In this retrospective analysis, patients with already reirradiated irresectable recurrent HNSCC, for whom palliative chemotherapy was unsuccessful or impossible, were offered microbrachytherapy with HoMS...
January 5, 2018: Nuclear Medicine Communications
https://www.readbyqxmd.com/read/29283270/an-east-west-comparison-of-self-care-barriers-in-heart-failure
#8
Shir Lynn Lim, Siew Pang Chan, Kim Yee Lee, Anne Ching, Richard J Holden, Karen F Miller, Alan B Storrow, Carolyn Sp Lam, Sean P Collins
BACKGROUND: Barriers in heart failure self-care contribute to heart failure hospitalizations, but geographic differences have not been well-studied. We aimed to compare self-care barriers in heart failure patients managed at tertiary centers in an Eastern (Singapore) versus a Western (USA) nation. METHODS: Acute heart failure patients were prospectively assessed with a standardized instrument comprising of 47 distinct self-care barriers. The multi-equation generalized structural equation model was used to evaluate for geographic differences in barriers experienced, and association of barriers with outcomes...
December 1, 2017: European Heart Journal. Acute Cardiovascular Care
https://www.readbyqxmd.com/read/29276607/ventilator-associated-respiratory-infection-in-a-resource-restricted-setting-impact-and-etiology
#9
Vu Dinh Phu, Behzad Nadjm, Nguyen Hoang Anh Duy, Dao Xuan Co, Nguyen Thi Hoang Mai, Dao Tuyet Trinh, James Campbell, Dong Phu Khiem, Tran Ngoc Quang, Huynh Thi Loan, Ha Son Binh, Quynh-Dao Dinh, Duong Bich Thuy, Huong Nguyen Phu Lan, Nguyen Hong Ha, Ana Bonell, Mattias Larsson, Hoang Minh Hoan, Đang Quoc Tuan, Hakan Hanberger, Hoang Nguyen Van Minh, Lam Minh Yen, Nguyen Van Hao, Nguyen Gia Binh, Nguyen Van Vinh Chau, Nguyen Van Kinh, Guy E Thwaites, Heiman F Wertheim, H Rogier van Doorn, C Louise Thwaites
Background: Ventilator-associated respiratory infection (VARI) is a significant problem in resource-restricted intensive care units (ICUs), but differences in casemix and etiology means VARI in resource-restricted ICUs may be different from that found in resource-rich units. Data from these settings are vital to plan preventative interventions and assess their cost-effectiveness, but few are available. Methods: We conducted a prospective observational study in four Vietnamese ICUs to assess the incidence and impact of VARI...
2017: Journal of Intensive Care
https://www.readbyqxmd.com/read/29248619/a-new-approach-for-assessing-and-training-drivers-speed-management
#10
Noelle LaVoie, Yi-Ching Lee, Anna Allison, James Parker
Motor vehicle crashes are the leading cause of death and injury for teens and speeding is a major contributor, particularly driving too fast for conditions (CDC, 2015, 2013; NHTSA, 2012; Lam, 2003; McKnight & McKnight, 2003). Speed management is a type of tacit knowledge learned through experience that combines speed perception with decisions about safety. Effective training and assessment of speed management requires a safe method for accumulating practice that includes realistic perceptual cues. This study investigated whether speed can be manipulated in an online environment using special effects technology without distorting speed perception...
December 14, 2017: Accident; Analysis and Prevention
https://www.readbyqxmd.com/read/29227879/re-thinking-pre-drinking-implications-from-a-sample-of-teenagers-who-drink-in-private-settings
#11
James Wilson, Rowan P Ogeil, Tina Lam, Simon Lenton, Belinda Lloyd, Lucy Burns, Alexandra Aiken, William Gilmore, Tanya Chikritzhs, Richard Mattick, Dan I Lubman, Steve Allsop
BACKGROUND: Pre-drinking is often defined as an economically-minded set of drinking practices engaged in prior to attending public entertainment areas, such as licensed venues. This paper explores motivations and practical considerations that a sample of teenagers describes as significant to 'pre-drinking', despite not attending licensed premises during their most recent risky drinking session. METHODS: Data were derived from the mixed-methods Young Australians Alcohol Reporting System (YAARS) project...
December 8, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29208258/durability-of-sirolimus-for-lymphangioleiomyomatosis
#12
Alexandra Martirossian, Shiwan Shah, Lola Carrete, Jose Valle, Vincent Valentine
Lymphangioleiomyomatosis (LAM), a rare, multisystem disorder primarily affecting women of reproductive age, is characterized by cystic-appearing lung lesions, progressive loss of lung function, chylous effusions and renal angiomyolipomas. Sirolimus, an mammalian target of rapamycin inhibitor, has been shown to stabilize lung function, reduce symptoms and resolve chylous effusions in the short term for patients with LAM. Herein, we report a premenopausal female with LAM who experienced complete and durable resolution of her chylothoraces with significant and sustained improvement in lung function on sirolimus...
December 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29179573/the-value-of-rehabilitation-medicine-for-patients-receiving-palliative-care
#13
Sarah A Wittry, Ny-Ying Lam, Thomas McNalley
BACKGROUND: Rehabilitation medicine is a multidisciplinary field aimed at improving patients' quality of life by improving function. Patients receiving palliative care frequently share common symptoms including fatigue, decreased functional independence, mood disorders, pain, and breathlessness. Many rehabilitation interventions can improve these symptoms. OBJECTIVE: To evaluate the scope and effectiveness of rehabilitation interventions and exercise programs in improving quality of life and distressing symptoms in patients receiving palliative care...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29162086/tribes-and-tribulations-interdisciplinary-ehealth-in-providing-services-for-people-with-a-traumatic-brain-injury-tbi
#14
M Hines, M Brunner, S Poon, M Lam, V Tran, D Yu, L Togher, T Shaw, E Power
BACKGROUND: eHealth has potential for supporting interdisciplinary care in contemporary traumatic brain injury (TBI) rehabilitation practice, yet little is known about whether this potential is being realised, or what needs to be done to further support its implementation. The purpose of this study was to explore health professionals' experiences of, and attitudes towards eHealth technologies to support interdisciplinary practice within rehabilitation for people after TBI. METHODS: A qualitative study using narrative analysis was conducted...
November 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29053335/success-rates-of-a-skeletal-anchorage-system-in-orthodontics-a-retrospective-analysis
#15
Raymond Lam, Mithran S Goonewardene, Brent P Allan, Junji Sugawara
OBJECTIVES: To evaluate the premise that skeletal anchorage with SAS miniplates are highly successful and predictable for a range of complex orthodontic movements. MATERIALS AND METHODS: This retrospective cross-sectional analysis consisted of 421 bone plates placed by one clinician in 163 patients (95 female, 68 male, mean age 29.4 years ± 12.02). Simple descriptive statistics were performed for a wide range of malocclusions and desired movements to obtain success, complication, and failure rates...
October 20, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/29031574/a-new-all-purpose-bilateral-cleft-lip-repair-bilateral-cheiloplasty-suitable-for-most-conditions
#16
Rong-Min Baek, Yujin Myung, Iehyon Park, Chang-Sik Pak, Baek-Kyu Kim, Vũ Ngọc Lâm, Jae Hoon Jeong
BACKGROUND: Only experienced surgeons can produce satisfactory results with most of the current surgical methods for bilateral cleft lip repair. The existing methods require not only preoperative orthodontic maneuvers but also accurate measurements for surgical design. We describe an easy-to-design and simple-to-execute general purpose surgical technique to repair most bilateral cleft lips. METHODS: A retrospective review was performed for the patients who underwent bilateral cleft lip repair using our novel method between 2003 and 2016...
September 25, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29024935/venous-thromboembolism-and-the-risk-of-death-and-graft-loss-in-kidney-transplant-recipients
#17
Ngan N Lam, Amit X Garg, Greg A Knoll, S Joseph Kim, Krista L Lentine, Eric McArthur, Kyla L Naylor, Sarah E Bota, Manish M Sood
BACKGROUND: The implications of venous thromboembolism (VTE) for morbidity and mortality in kidney transplant recipients are not well described. METHODS: We conducted a retrospective study using linked healthcare databases in Ontario, Canada to determine the risk and complications of VTE in kidney transplant recipients from 2003 to 2013. We compared the incidence rate of VTE in recipients (n = 4,343) and a matched (1:4) sample of the general population (n = 17,372)...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28988904/subcallosal-cingulate-deep-brain-stimulation-for-treatment-resistant-depression-a-multisite-randomised-sham-controlled-trial
#18
Paul E Holtzheimer, Mustafa M Husain, Sarah H Lisanby, Stephan F Taylor, Louis A Whitworth, Shawn McClintock, Konstantin V Slavin, Joshua Berman, Guy M McKhann, Parag G Patil, Barry R Rittberg, Aviva Abosch, Ananda K Pandurangi, Kathryn L Holloway, Raymond W Lam, Christopher R Honey, Joseph S Neimat, Jaimie M Henderson, Charles DeBattista, Anthony J Rothschild, Julie G Pilitsis, Randall T Espinoza, Georgios Petrides, Alon Y Mogilner, Keith Matthews, DeLea Peichel, Robert E Gross, Clement Hamani, Andres M Lozano, Helen S Mayberg
BACKGROUND: Deep brain stimulation (DBS) of the subcallosal cingulate white matter has shown promise as an intervention for patients with chronic, unremitting depression. To test the safety and efficacy of DBS for treatment-resistant depression, a prospective, randomised, sham-controlled trial was conducted. METHODS: Participants with treatment-resistant depression were implanted with a DBS system targeting bilateral subcallosal cingulate white matter and randomised to 6 months of active or sham DBS, followed by 6 months of open-label subcallosal cingulate DBS...
October 4, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28986225/pediatric-intracranial-aneurysms-considerations-and-recommendations-for-follow-up-imaging
#19
REVIEW
Michael George Zaki Ghali, Visish M Srinivasan, Jacob Cherian, Louis Kim, Adnan Siddiqui, M Ali Aziz-Sultan, Michael Froehler, Ajay Wakhloo, Eric Savageau, Ansaar Rai, Stephen R Chen, Jeremiah Johnson, Sandi K Lam, Peter Kan
BACKGROUND: Pediatric intracranial aneurysms (IAs) are rare. Compared to adult IAs, they are more commonly giant, fusiform, or dissecting. Their treatment often proves more complex and recurrence rate and de novo aneurysmogenesis incidence is higher. A consensus regarding the most appropriate algorithm for following pediatric IAs is lacking. METHODS: We thus sought to generate recommendations based on the reported experience in the literature with pediatric IAs, through a thorough review of the Pubmed database, discussion with experienced neurointerventionalists, and our own experience...
October 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28968453/help-seeking-behaviours-for-psychological-distress-amongst-chinese-patients
#20
Kai Sing Sun, Tai Pong Lam, Kwok Fai Lam, Leon Piterman, Tak Lam Lo, David Vai Kiong Chao, Edmund Wing Wo Lam
BACKGROUND: The stepped care model for psychological distress has been promoted in recent years, leading to the enhancing roles of primary care professionals and alternative sources of help. However, most of the research findings come from Western countries. This study investigates help-seeking behaviours of Chinese patients among different types of professional and alternative sources for psychological distress in Hong Kong. METHODS: A questionnaire survey was conducted with 1626 adult primary care attenders from 13 private and 6 public clinics, 650 (40...
2017: PloS One
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