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https://www.readbyqxmd.com/read/29227879/re-thinking-pre-drinking-implications-from-a-sample-of-teenagers-who-drink-in-private-settings
#1
James Wilson, Rowan P Ogeil, Tina Lam, Simon Lenton, Belinda Lloyd, Lucy Burns, Alexandra Aiken, William Gilmore, Tanya Chikritzhs, Richard Mattick, Dan I Lubman, Steve Allsop
BACKGROUND: Pre-drinking is often defined as an economically-minded set of drinking practices engaged in prior to attending public entertainment areas, such as licensed venues. This paper explores motivations and practical considerations that a sample of teenagers describes as significant to 'pre-drinking', despite not attending licensed premises during their most recent risky drinking session. METHODS: Data were derived from the mixed-methods Young Australians Alcohol Reporting System (YAARS) project...
December 8, 2017: International Journal on Drug Policy
https://www.readbyqxmd.com/read/29208258/durability-of-sirolimus-for-lymphangioleiomyomatosis
#2
Alexandra Martirossian, Shiwan Shah, Lola Carrete, Jose Valle, Vincent Valentine
Lymphangioleiomyomatosis (LAM), a rare, multisystem disorder primarily affecting women of reproductive age, is characterized by cystic-appearing lung lesions, progressive loss of lung function, chylous effusions and renal angiomyolipomas. Sirolimus, an mammalian target of rapamycin inhibitor, has been shown to stabilize lung function, reduce symptoms and resolve chylous effusions in the short term for patients with LAM. Herein, we report a premenopausal female with LAM who experienced complete and durable resolution of her chylothoraces with significant and sustained improvement in lung function on sirolimus...
December 2017: American Journal of the Medical Sciences
https://www.readbyqxmd.com/read/29179573/the-value-of-rehabilitation-medicine-for-patients-receiving-palliative-care
#3
Sarah A Wittry, Ny-Ying Lam, Thomas McNalley
BACKGROUND: Rehabilitation medicine is a multidisciplinary field aimed at improving patients' quality of life by improving function. Patients receiving palliative care frequently share common symptoms including fatigue, decreased functional independence, mood disorders, pain, and breathlessness. Many rehabilitation interventions can improve these symptoms. OBJECTIVE: To evaluate the scope and effectiveness of rehabilitation interventions and exercise programs in improving quality of life and distressing symptoms in patients receiving palliative care...
January 1, 2017: American Journal of Hospice & Palliative Care
https://www.readbyqxmd.com/read/29162086/tribes-and-tribulations-interdisciplinary-ehealth-in-providing-services-for-people-with-a-traumatic-brain-injury-tbi
#4
M Hines, M Brunner, S Poon, M Lam, V Tran, D Yu, L Togher, T Shaw, E Power
BACKGROUND: eHealth has potential for supporting interdisciplinary care in contemporary traumatic brain injury (TBI) rehabilitation practice, yet little is known about whether this potential is being realised, or what needs to be done to further support its implementation. The purpose of this study was to explore health professionals' experiences of, and attitudes towards eHealth technologies to support interdisciplinary practice within rehabilitation for people after TBI. METHODS: A qualitative study using narrative analysis was conducted...
November 21, 2017: BMC Health Services Research
https://www.readbyqxmd.com/read/29053335/success-rates-of-a-skeletal-anchorage-system-in-orthodontics-a-retrospective-analysis
#5
Raymond Lam, Mithran S Goonewardene, Brent P Allan, Junji Sugawara
OBJECTIVES: To evaluate the premise that skeletal anchorage with SAS miniplates are highly successful and predictable for a range of complex orthodontic movements. MATERIALS AND METHODS: This retrospective cross-sectional analysis consisted of 421 bone plates placed by one clinician in 163 patients (95 female, 68 male, mean age 29.4 years ± 12.02). Simple descriptive statistics were performed for a wide range of malocclusions and desired movements to obtain success, complication, and failure rates...
October 20, 2017: Angle Orthodontist
https://www.readbyqxmd.com/read/29031574/a-new-all-purpose-bilateral-cleft-lip-repair-bilateral-cheiloplasty-suitable-for-most-conditions
#6
Rong-Min Baek, Yujin Myung, Iehyon Park, Chang-Sik Pak, Baek-Kyu Kim, Vũ Ngọc Lâm, Jae Hoon Jeong
BACKGROUND: Only experienced surgeons can produce satisfactory results with most of the current surgical methods for bilateral cleft lip repair. The existing methods require not only preoperative orthodontic maneuvers but also accurate measurements for surgical design. We describe an easy-to-design and simple-to-execute general purpose surgical technique to repair most bilateral cleft lips. METHODS: A retrospective review was performed for the patients who underwent bilateral cleft lip repair using our novel method between 2003 and 2016...
September 25, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/29024935/venous-thromboembolism-and-the-risk-of-death-and-graft-loss-in-kidney-transplant-recipients
#7
Ngan N Lam, Amit X Garg, Greg A Knoll, S Joseph Kim, Krista L Lentine, Eric McArthur, Kyla L Naylor, Sarah E Bota, Manish M Sood
BACKGROUND: The implications of venous thromboembolism (VTE) for morbidity and mortality in kidney transplant recipients are not well described. METHODS: We conducted a retrospective study using linked healthcare databases in Ontario, Canada to determine the risk and complications of VTE in kidney transplant recipients from 2003 to 2013. We compared the incidence rate of VTE in recipients (n = 4,343) and a matched (1:4) sample of the general population (n = 17,372)...
2017: American Journal of Nephrology
https://www.readbyqxmd.com/read/28988904/subcallosal-cingulate-deep-brain-stimulation-for-treatment-resistant-depression-a-multisite-randomised-sham-controlled-trial
#8
Paul E Holtzheimer, Mustafa M Husain, Sarah H Lisanby, Stephan F Taylor, Louis A Whitworth, Shawn McClintock, Konstantin V Slavin, Joshua Berman, Guy M McKhann, Parag G Patil, Barry R Rittberg, Aviva Abosch, Ananda K Pandurangi, Kathryn L Holloway, Raymond W Lam, Christopher R Honey, Joseph S Neimat, Jaimie M Henderson, Charles DeBattista, Anthony J Rothschild, Julie G Pilitsis, Randall T Espinoza, Georgios Petrides, Alon Y Mogilner, Keith Matthews, DeLea Peichel, Robert E Gross, Clement Hamani, Andres M Lozano, Helen S Mayberg
BACKGROUND: Deep brain stimulation (DBS) of the subcallosal cingulate white matter has shown promise as an intervention for patients with chronic, unremitting depression. To test the safety and efficacy of DBS for treatment-resistant depression, a prospective, randomised, sham-controlled trial was conducted. METHODS: Participants with treatment-resistant depression were implanted with a DBS system targeting bilateral subcallosal cingulate white matter and randomised to 6 months of active or sham DBS, followed by 6 months of open-label subcallosal cingulate DBS...
October 4, 2017: Lancet Psychiatry
https://www.readbyqxmd.com/read/28986225/pediatric-intracranial-aneurysms-considerations-and-recommendations-for-follow-up-imaging
#9
REVIEW
Michael George Zaki Ghali, Visish M Srinivasan, Jacob Cherian, Louis Kim, Adnan Siddiqui, M Ali Aziz-Sultan, Michael Froehler, Ajay Wakhloo, Eric Savageau, Ansaar Rai, Stephen R Chen, Jeremiah Johnson, Sandi K Lam, Peter Kan
BACKGROUND: Pediatric intracranial aneurysms (IAs) are rare. Compared to adult IAs, they are more commonly giant, fusiform, or dissecting. Their treatment often proves more complex and recurrence rate and de novo aneurysmogenesis incidence is higher. A consensus regarding the most appropriate algorithm for following pediatric IAs is lacking. METHODS: We thus sought to generate recommendations based on the reported experience in the literature with pediatric IAs, through a thorough review of the Pubmed database, discussion with experienced neurointerventionalists, and our own experience...
October 3, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/28968453/help-seeking-behaviours-for-psychological-distress-amongst-chinese-patients
#10
Kai Sing Sun, Tai Pong Lam, Kwok Fai Lam, Leon Piterman, Tak Lam Lo, David Vai Kiong Chao, Edmund Wing Wo Lam
BACKGROUND: The stepped care model for psychological distress has been promoted in recent years, leading to the enhancing roles of primary care professionals and alternative sources of help. However, most of the research findings come from Western countries. This study investigates help-seeking behaviours of Chinese patients among different types of professional and alternative sources for psychological distress in Hong Kong. METHODS: A questionnaire survey was conducted with 1626 adult primary care attenders from 13 private and 6 public clinics, 650 (40...
2017: PloS One
https://www.readbyqxmd.com/read/28927326/decision-outcomes-in-women-offered-noninvasive-prenatal-test-nipt-for-positive-down-screening-results
#11
Tsz-Kin Lo, Kelvin Yuen-Kwong Chan, Anita Sik-Yau Kan, Po-Lam So, Choi-Wah Kong, Shui-Lam Mak, Chung-Nin Lee
In this first Asian study, the decision outcomes (decision conflict, decision regret, and anxiety) of 262 pregnant women offered noninvasive prenatal test (NIPT) for high-risk Down screening results were assessed. Decision conflict was experienced by 3.5% and level of decisional regret low (mean score 15.7, 95%CI 13.2-18.3). All 13 cases of decisional regret were NIPT acceptors. Elevated anxiety was experienced by 55.9% at the time of decision making about NIPT and persistent in 30.3%. Insufficient knowledge about NIPT was associated with elevated anxiety at decision making (p = ...
September 19, 2017: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/28872442/added-value-of-computer-aided-ct-image-features-for-early-lung-cancer-diagnosis-with-small-pulmonary-nodules-a-matched-case-control-study
#12
Peng Huang, Seyoun Park, Rongkai Yan, Junghoon Lee, Linda C Chu, Cheng T Lin, Amira Hussien, Joshua Rathmell, Brett Thomas, Chen Chen, Russell Hales, David S Ettinger, Malcolm Brock, Ping Hu, Elliot K Fishman, Edward Gabrielson, Stephen Lam
Purpose To test whether computer-aided diagnosis (CAD) approaches can increase the positive predictive value (PPV) and reduce the false-positive rate in lung cancer screening for small nodules compared with human reading by thoracic radiologists. Materials and Methods A matched case-control sample of low-dose computed tomography (CT) studies in 186 participants with 4-20-mm noncalcified lung nodules who underwent biopsy in the National Lung Screening Trial (NLST) was selected. Variables used for matching were age, sex, smoking status, chronic obstructive pulmonary disease status, body mass index, study year of the positive screening test, and screening results...
September 5, 2017: Radiology
https://www.readbyqxmd.com/read/28870666/tenofovir-alafenamide-as-a-rescue-therapy-in-a-patient-with-hbv-cirrhosis-with-a-history-of-fanconi-syndrome-and-multidrug-resistance
#13
Glenda Grossi, Alessandro Loglio, Floriana Facchetti, Marta Borghi, Roberta Soffredini, Enrico Galmozzi, Giovanna Lunghi, Anuj Gaggar, Pietro Lampertico
Tenofovir disoproxil fumarate (TDF) is a recommended first-line therapy for both naïve and experienced patients with chronic hepatitis B (CHB), although reduced estimated glomerular filtration rate (eGFR), hypophosphatemia, hyperphosphaturia and Fanconi syndrome have been reported in some patients. Entecavir (ETV) could be considered as a rescue therapy for TDF-treated patients developing renal dysfunction, though patients with prior history of treatment with lamivudine (LAM) can develop ETV resistance strains, which can lead to potentially severe hepatitis flares...
September 21, 2017: Journal of Hepatology
https://www.readbyqxmd.com/read/28858441/the-thinc-integrated-tool-thinc-it-screening-assessment-for-cognitive-dysfunction-validation-in-patients-with-major-depressive-disorder
#14
Roger S McIntyre, Michael W Best, Christopher R Bowie, Nicole E Carmona, Danielle S Cha, Yena Lee, Mehala Subramaniapillai, Rodrigo B Mansur, Harry Barry, Bernhard T Baune, Larry Culpepper, Philippe Fossati, Tracy L Greer, Catherine Harmer, Esther Klag, Raymond W Lam, Hans-Ulrich Wittchen, John Harrison
OBJECTIVE: To validate the THINC-integrated tool (THINC-it)-a freely available, patient-administered, computerized screening tool integrating subjective and objective measures of cognitive function in adults with major depressive disorder (MDD). METHODS: Subjects aged 18 to 65 years (n = 100) with recurrent MDD experiencing a major depressive episode of at least moderate severity were evaluated and compared to age-, sex-, and education-matched healthy controls (n = 100)...
July 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28741262/maternal-mental-quality-of-life-mediates-the-associations-between-intimate-partner-abuse-against-mothers-and-their-children-s-behaviours-and-quality-of-life-in-low-income-chinese-families
#15
Vivian Yawei Guo, Esther Yee Tak Yu, Rosa Sze Man Wong, Patrick Ip, Agnes Fung Yee Tiwari, Carlos King Ho Wong, Colman Siu Cheung Fung, Wilfred Hing Sang Wong, Cindy Lo Kuen Lam
PURPOSE: To explore the association between maternal intimate partner abuse (IPA) and their children's health-related quality of life (HRQOL) and behavioural problem, and to establish a mediation model and investigate the mediating role of mothers' HRQOL on this association. METHODS: A cross-sectional study was conducted on 197 mothers of 227 children (112 boys and 115 girls) from low-income Chinese families. The mothers were asked to complete the 5-item abuse assessment screen questionnaire for the presence of IPA, the Chinese (Hong Kong) version of 12-item Short-Form Health Survey (SF-12) for their HRQOL and a structured socio-demographics questionnaire...
December 2017: Quality of Life Research
https://www.readbyqxmd.com/read/28733699/a-prospective-study-of-docetaxel-associated-pain-syndrome
#16
Nicholas Chiu, Liying Zhang, Rebecca Dent, Angie Giotis, Jenna van Draanen, Daniela Gallo-Hershberg, Leonard Chiu, Ronald Chow, Bo Angela Wan, Mark Pasetka, Jordan Stinson, Erica Stacey, Sunil Verma, Henry Lam, Edward Chow, Carlo DeAngelis
PURPOSE: To investigate the natural history of taxane-associated acute pain syndrome (TAPS) in a docetaxel patient cohort and to examine the long-term manifestation of TAPS. PATIENTS AND METHODS: For three consecutive treatment cycles, taxane-naive breast cancer patients completed diaries on days 1-7, 14, and 21 and telephone questionnaires 1, 3, 6, 9, and 12 months following treatment. Questionnaires to assess pain and interference were adapted from the Brief Pain Inventory...
July 22, 2017: Supportive Care in Cancer: Official Journal of the Multinational Association of Supportive Care in Cancer
https://www.readbyqxmd.com/read/28697858/accelerated-partial-breast-irradiation-for-elderly-women-with-early-breast-cancer-a-compromise-between-whole-breast-irradiation-and-omission-of-radiotherapy
#17
Shakeel Sumodhee, Johan Levy, Emmanuel Chamorey, Daniel Lam Cham Kee, Marie-Eve Chand, Mathieu Gautier, Isabelle Peyrottes, Emmanuel Barranger, Jean-Michel Hannoun-Levi
PURPOSE: Regarding adjuvant radiation therapy making decision for elderly women, Albert (2013) published a nomogram predicting the mastectomy-free survival (MFS) rate with or without adjuvant irradiation. Based on this approach, we proposed to investigate the use of accelerated partial breast irradiation (APBI) vs. whole breast irradiation (WBI) or endocrine therapy alone in elderly low-risk breast cancer patients. METHODS AND MATERIALS: For each elderly woman treated by conserving surgery and APBI (multicatheter interstitial high-dose-rate brachytherapy), 5- and 10-year MFS rates were calculated...
July 8, 2017: Brachytherapy
https://www.readbyqxmd.com/read/28678984/association-of-neural-and-emotional-impacts-of-reward-prediction-errors-with-major-depression
#18
Robb B Rutledge, Michael Moutoussis, Peter Smittenaar, Peter Zeidman, Tanja Taylor, Louise Hrynkiewicz, Jordan Lam, Nikolina Skandali, Jenifer Z Siegel, Olga T Ousdal, Gita Prabhu, Peter Dayan, Peter Fonagy, Raymond J Dolan
Importance: Major depressive disorder (MDD) is associated with deficits in representing reward prediction errors (RPEs), which are the difference between experienced and predicted reward. Reward prediction errors underlie learning of values in reinforcement learning models, are represented by phasic dopamine release, and are known to affect momentary mood. Objective: To combine functional neuroimaging, computational modeling, and smartphone-based large-scale data collection to test, in the absence of learning-related concerns, the hypothesis that depression attenuates the impact of RPEs...
August 1, 2017: JAMA Psychiatry
https://www.readbyqxmd.com/read/28677270/burnout-and-its-association-with-resilience-in-nurses-a-cross-sectional-study-nurse-burnout-and-resilience
#19
Yu-Fang Guo, Yuan-Hui Luo, Louisa Lam, Wendy Cross, Virginia Plummer, Jing-Ping Zhang
AIMS AND OBJECTIVES: To investigate the prevalence and extent of burnout on nurses and its association with personal resilience. BACKGROUND: With the worldwide shortage of nurses, nurse burnout is considered one of the main contributing factors and has been the focus of studies in recent years. Given the well-documented high level of burnout among nurses, resilience is expected to be a significant predictor of nurse burnout. The association between burnout and resilience has not previously been investigated extensively...
July 5, 2017: Journal of Clinical Nursing
https://www.readbyqxmd.com/read/28664241/the-epidemiology-of-current-depression-in-macau-china-towards-a-plan-for-mental-health-action
#20
Brian J Hall, Agnes Iok Fong Lam, Tat Leong Wu, Wai-Kai Hou, Carl Latkin, Sandro Galea
PURPOSE: Macau is a Special Administrative Region in China that has experienced tremendous development in its gambling industry during its post-colonial years. To inform mental health planning, this study presents the first population estimates and correlates of the current depression in Macau. METHODS: A population-representative sample of 1068 Macau Chinese citizens aged 18 or above responded to a household telephone survey in January, 2015. The Patient Health Questionnaire-9 measured the current depression...
October 2017: Social Psychiatry and Psychiatric Epidemiology
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