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Severiano R Silva, Rita Payan-Carreira, Cristina M Guedes, Simão Coelho, Ana Sofia Santos
BACKGROUND: Obesity and emaciation in horses have major detrimental effects on health and morbidity, reproductive failure, work performance or carcass quality. Scoring is a current management tool used to assess and monitor equine body condition due to its simplicity and low cost. However, accurate assessment of obesity remains a challenge, even though a number of approaches have been tested, particularly for research purposes on adiposity. Their merit is usually validated by comparison with standard scoring methods...
October 20, 2016: Acta Veterinaria Scandinavica
Zhen Huo, Tao Lu, Zhiyong Liang, Fan Ping, Jie Shen, Jingjing Lu, Wenbing Ma, Dachun Zhao, Dingrong Zhong
BACKGROUND: Isolated hypothalamic-pituitary Langerhans cell histiocytosis (HPLCH) is very rare. We investigated the clinicopathological characteristics, endocrine function changes, BRAF(V600E) mutations and treatments of isolated HPLCH. METHODS: We identified seven patients with isolated HPLCH by reviewing the clinical and pathological files in our hospital from 2007 to 2015. The clinical characteristics of the seven patients were retrospectively reviewed, especially the endocrine function changes...
October 19, 2016: Diagnostic Pathology
John Arvesen, J Tracy Watson, Heidi Israel
OBJECTIVE: To determine the efficacy of a hexapod external fixator (TSF) and its ability to perform six-axis correction in restoring deformities associated with distal tibial nonunions. DESIGN: Consecutive retrospective case review. SETTING: St. Louis University Hospital. Level One Trauma Center. PATIENTS/PARTICIPANTS: 37 patients with distal tibial nonunion with greater than 5 degrees of deformity in any plane. Patients were excluded who were less than 18 years of age, had tibial deformities less than 5 degrees, had proximal or middle tibial deformities or had less than one year of follow up...
October 7, 2016: Journal of Orthopaedic Trauma
Courtney N Gleason, Deanna L Kerkhof, Elizabeth A Cilia, Maria A Lanyi, Jonathan Finnoff, Dai Sugimoto, Gianmichel D Corrado
OBJECTIVE: The traditional history and physical (H&P) is a poor screening modality to identify athletes at risk for sudden cardiac death. Although better than H&P alone, electrocardiograms (ECG) have also been found to have high false-positive rates. A limited portable ECG by a frontline physician (PEFP) performed during preparticipation physical examination (PPE) allows for direct measurements of the heart to more accurately identify athletes with structural abnormalities. Therefore, it is worthwhile to assess the feasibility of incorporating limited PEFP as part of PPEs...
October 13, 2016: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
Kirsten W Slagter, Gerry M Raghoebar, Arjan Vissink, Henny J A Meijer
BACKGROUND: Sufficient buccal bone is important for optimal esthetic results of implant treatment in the anterior region. It can be measured with cone beam computed tomography (CBCT), but background scattering and problems with standardization of the measurements are encountered. The aim was to develop a method for reliable, reproducible measurements on CBCTs. METHODS: Using a new method, buccal bone thickness was measured on ten CBCTs at six positions along the implant axis...
December 2015: Int J Implant Dent
Miguel Ángel Claudio-Catalán, Felipe Medrano, Hugo Tlahuext, Carolina Godoy-Alcántar
The asymmetric unit of the title compound, C56H50N6O8S2·3C6H4Cl2, contains two half-mol-ecules of the parent, A and B, which both have crystallographic inversion symmetry, together with three 2,3-di-chloro-benzene mol-ecules of solvation. Mol-ecules A and B are conformationally similar, with dihedral angles between the central naphthalenedi-imide ring and the peripheral naphthalene and benzyl rings of 2.43 (7), 81.87 (7)° (A) and 3.95 (7), 84.88 (7)° (B), respectively. The conformations are stabilized by the presence of intra-molecular π-π inter-actions between the naphthalene ring and the six-membered di-imide ring of the central naphthalenedi-imide moiety, with ring centroid-to-centroid distances of 3...
October 1, 2016: Acta Crystallographica. Section E, Crystallographic Communications
Guillaume Zahnd, Kostas Kapellas, Martijn van Hattem, Anouk van Dijk, André Sérusclat, Philippe Moulin, Aad van der Lugt, Michael Skilton, Maciej Orkisz
The aim of this study was to introduce and evaluate a contour segmentation method to extract the interfaces of the intima-media complex in carotid B-mode ultrasound images. The method was applied to assess the temporal variation of intima-media thickness during the cardiac cycle. The main methodological contribution of the proposed approach is the introduction of an augmented dimension to process 2-D images in a 3-D space. The third dimension, which is added to the two spatial dimensions of the image, corresponds to the tentative local thickness of the intima-media complex...
October 12, 2016: Ultrasound in Medicine & Biology
Maciej Antczak, Mariusz Popenda, Tomasz Zok, Joanna Sarzynska, Tomasz Ratajczak, Katarzyna Tomczyk, Ryszard W Adamiak, Marta Szachniuk
RNAComposer is a fully automated, web-interfaced system for RNA 3D structure prediction, freely available at and Its main components are: manually curated database of RNA 3D structure elements, highly efficient computational engine and user-friendly web application. In this paper, we demonstrate how the latest additions to the system allow the user to significantly affect the process of 3D model composition on several computational levels...
October 14, 2016: Acta Biochimica Polonica
Adam H Breiteneicher, Bo Norby, Kurt S Schulz, Sharon C Kerwin, Don A Hulse, Derek B Fox, W Brian Saunders
OBJECTIVE: To determine the effect of sliding humeral osteotomy (SHO) on frontal plane thoracic limb alignment in standing and recumbent limb positions. STUDY DESIGN: Canine cadaveric study. SAMPLE POPULATION: Canine thoracic limbs (n=15 limb pairs). METHODS: Limbs acquired from healthy Labrador Retrievers euthanatized for reasons unrelated to this study were mounted in a limb press and aligned in a standing position followed by axial loading at 30% body weight...
October 13, 2016: Veterinary Surgery: VS
Chang Sin Kim, Sora Park, Lucy Youngmin Eun
BACKGROUND: The speckle tracking echocardiography can benefit to assess the regional myocardial deformations. Although, previous reports suggested no significant change in left ventricular (LV) torsion with aging, there are certain differences in LV rotation at the base and apex. The purpose of this study was to evaluate the change and relationship of LV rotation for torsion with aging in children. METHODS: Forty healthy children were recruited and divided into two groups of twenty based on whether the children were preschool-age (2-6 years of age) or school-age (7-12 years of age)...
September 2016: Journal of Cardiovascular Ultrasound
Bart W J Philips, Ansje S Fortuin, Stephan Orzada, Tom W J Scheenen, Marnix C Maas
PURPOSE: Pelvic lymph node (PLN) metastases are often smaller than 5 mm and difficult to detect. This work presents a method to perform PLN imaging with ultrahigh-field MRI, using spectrally selective excitation to acquire water and lipid-selective imaging at high spatial resolution. METHODS: A 3D water-selective multigradient echo (mGRE) sequence and lipid-selective gradient echo (GRE) sequence were tested in six healthy volunteers on a 7 Tesla (T) MRI system, using time interleaved acquisition of modes (TIAMO) to improve image homogeneity...
October 7, 2016: Magnetic Resonance in Medicine: Official Journal of the Society of Magnetic Resonance in Medicine
Keyong Yuan, Chenguang Niu, Qian Xie, Wenxin Jiang, Li Gao, Zhengwei Huang, Rui Ma
Minimally invasive endodontics emphasizes preservation of a maximal amount of healthy tooth tissue. However, whether the tooth structure preserved by minimally invasive endodontics can maintain higher fracture resistance is unclear. This study aimed to compare the biomechanics on teeth after minimally invasive (MI) preparation and straight-line (SL) preparation using finite element analysis. Six finite element analysis models of a mandibular first molar were constructed and divided into two groups (MI and SL)...
October 5, 2016: European Journal of Oral Sciences
Savvas J Constantinou, Ryan M Pace, A J Stangl, Lisa M Nagy, Terri A Williams
Wnt genes are a family of conserved glycoprotein ligands that play a role in a wide variety of cell and developmental processes, from cell proliferation to axis elongation. There are 13 Wnt subfamilies found among metazoans. Eleven of these appear conserved in arthropods with a pattern of loss during evolution of as many as six subfamilies among hexapods. Here we report on Wnt genes in the branchiopod crustacean, Thamnocephalus platyurus, including the first documentation of the expression of the complete Wnt gene family in a crustacean...
October 3, 2016: Evolution & Development
Eileen M Condon
Salivary cortisol is considered to be a safe and noninvasive measure of hypothalamic-pituitary-adrenal axis functioning, and is a commonly measured biomarker of the human stress response in pediatric research. However, cortisol is highly variable and sensitive to a wide range of factors, creating a challenge for reliable salivary cortisol collection in the community setting. Furthermore, the acceptability of salivary cortisol collection in community samples of children is largely unknown. The purpose of this integrative review was to investigate current evidence on the acceptability and feasibility of salivary cortisol collection in community samples of children...
September 30, 2016: Research in Nursing & Health
Choukri Mekkaoui, Timothy G Reese, Marcel P Jackowski, Stephen F Cauley, Kawin Setsompop, Himanshu Bhat, David E Sosnovik
Purpose To develop a clinically feasible whole-heart free-breathing diffusion-tensor (DT) magnetic resonance (MR) imaging approach with an imaging time of approximately 15 minutes to enable three-dimensional (3D) tractography. Materials and Methods The study was compliant with HIPAA and the institutional review board and required written consent from the participants. DT imaging was performed in seven healthy volunteers and three patients with pulmonary hypertension by using a stimulated echo sequence. Twelve contiguous short-axis sections and six four-chamber sections that covered the entire left ventricle were acquired by using simultaneous multisection (SMS) excitation with a blipped-controlled aliasing in parallel imaging readout...
September 28, 2016: Radiology
WeiJen Lai, Yoshiyuki Midorikawa, Zuisei Kanno, Hiroshi Takemura, Kazuhiro Suga, Kohei Soga, Takashi Ono, Motohiro Uo
We developed a device to evaluate the orthodontic force applied by systems requiring high operability. A life-sized, two-tooth model was designed, and the measurements were performed using a custom-made jointed attachment, referred to as an "action stick", to allow clearance for the oversized six-axis sensors. This tooth-sensor apparatus was accurately calibrated, and the error was limited. Vector analysis and rotating coordinate transformation were required to derive the force and moment at the tooth from the sensor readings...
September 29, 2016: Dental Materials Journal
Luis C Morales, Fernando Alvarado, José A Corredor, Andrés Rodríguez
BACKGROUND CONTEXT: Many etiologies can lead to atlantoaxial subluxaion. In Grisel's syndrome, this subluxation occurs spontaneously after inflammatory processes of the head and neck. Diagnosis is typically based on clinical history and a strong suspicion of this syndrome. Non-surgical treatment most often resolves the symptoms, however in some cases surgical treatment is necessary to repair the subluxation. Various surgical techniques and instrumentation systems have been used to treat atlantoaxial subluxation, although there is no consensus regarding the best treatment method for the pediatric population...
September 23, 2016: Spine Journal: Official Journal of the North American Spine Society
James Wilkerson, Ebrahim Paryavi, Hyunchul Kim, Anand Murthi, Raymond A Pensy
OBJECTIVES: Although most clavicular fractures are amenable to nonoperative management, metadiaphyseal fractures are considerably more complex, with rates of suboptimal healing as high as 75% when treated nonoperatively. The poor results are ascribed to the deforming forces on the distal clavicle from the surrounding muscles and the weight of the arm. It recently has been noted that some operative fixations of these fractures are also failing when a standard superiorly placed plate is used...
September 20, 2016: Journal of Orthopaedic Trauma
Mostafa Arastounia
This study proposes fully-automated methods for as-built model generation of subway tunnels employing mobile Light Detection and Ranging (LiDAR) data. The employed dataset is acquired by a Velodyne HDL 32E and covers 155 m of a subway tunnel containing six million points. First, the tunnel's main axis and cross sections are extracted. Next, a preliminary model is created by fitting an ellipse to each extracted cross section. The model is refined by employing residual analysis and Baarda's data snooping method to eliminate outliers...
2016: Sensors
Nicholas H Farina, Areg Zingiryan, Jacqueline A Akech, Cody J Callahan, Huimin Lu, Janet L Stein, Lucia R Languino, Gary S Stein, Jane B Lian
While decades of research have identified molecular pathways inducing and promoting stages of prostate cancer malignancy, studies addressing dynamic changes of cancer-related regulatory factors in a prostate tumor progression model are limited. Using the TRAMP mouse model of human prostate cancer, we address mechanisms of deregulation for the cancer-associated transcription factors, Runx1 and Runx2 by identifying microRNAs with reciprocal expression changes at six time points during 33 weeks of tumorigenesis...
September 13, 2016: Oncotarget
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