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Ahmed A Aljohaney
AIMS: The aim of the study was to evaluate the clinical utility and safety of endobronchial ultrasound-guided transbronchial needle aspiration (EBUS-TBNA) in patients with mediastinal and hilar lymphadenopathy and to explicitly describe the utility of this procedure in patient's outcome. METHODS: A retrospective review and analysis was conducted on 52 patients with mediastinal or hilar lymphadenopathy who underwent EBUS-TBNA from June 2012 to June 2016. All the patients were evaluated by computed tomography (CT) chest with contrast before EBUS examination...
April 2018: Annals of Thoracic Medicine
Kristine A Ensign, Brian M Dodge, Debra Herbenick, Carrie L Docherty
CONTEXT:   The unique contexts in which athletic trainers (ATs) work require specific tools in order to understand their attitudes toward diverse patient populations, including sexual and gender minorities. OBJECTIVE:   To develop and validate the Attitudes Toward Transgender Patients (ATTP) instrument for ATs. DESIGN:   Cross-sectional study. SETTING:   Semistructured interviews, paper-based questionnaire, and electronic questionnaire...
April 18, 2018: Journal of Athletic Training
Sergio Sanchez-Martinez, Nicolas Duchateau, Tamas Erdei, Gabor Kunszt, Svend Aakhus, Anna Degiovanni, Paolo Marino, Erberto Carluccio, Gemma Piella, Alan G Fraser, Bart H Bijnens
BACKGROUND: Current diagnosis of heart failure with preserved ejection fraction (HFpEF) is suboptimal. We tested the hypothesis that comprehensive machine learning (ML) of left ventricular function at rest and exercise objectively captures differences between HFpEF and healthy subjects. METHODS AND RESULTS: One hundred fifty-six subjects aged >60 years (72 HFpEF+33 healthy for the initial analyses; 24 hypertensive+27 breathless for independent evaluation) underwent stress echocardiography, in the MEDIA study (Metabolic Road to Diastolic Heart Failure)...
April 2018: Circulation. Cardiovascular Imaging
A L Belli, R B Reis, A Veronese, R Moreira, K Flanagan, J Driver, C D Nelson, J A Clapper, M A Ballou, K C Jeong, R C Chebel
Weaning may be associated with negative energy balance and body weight loss when calves are still immunologically immature, predisposing them to infectious diseases. The aim of the present experiment was to investigate the effects of treatment of preweaning dairy calves with recombinant bovine somatotropin (rbST) on the somatotropic axis, selected immune parameters, and hematology of calves around weaning. Thirty-six Holstein female calves were randomly assigned to receive 1.5 to 1.8 mg of rbST (Posilac, Elanco Animal Health, Greenfield, IN) per kilogram of body weight or to receive injections of saline (saline solution 0...
April 11, 2018: Journal of Dairy Science
Yash J Avashia, Ronnie L Shammas, Luke P Poveromo, Travis J Dekker, Jacob W Brubacher, Marc J Richard, David S Ruch, Suhail K Mithani
BACKGROUND: Elbow wounds pose a reconstructive challenge. Prior studies have described the vascular anatomy of both the brachioradialis (BR) and flexor carpi ulnaris (FCU) muscle flaps. The goal of this study was to describe the distal flap perfusion of the flexor carpi radialis (FCR), with a direct comparison of the BR, FCU, and FCR muscle flaps for coverage around the elbow. METHODS: Six fresh-frozen upper extremity specimens were dissected for BR, FCR, and FCU flaps...
March 28, 2018: Plastic and Reconstructive Surgery
Dashdavaa Batkhishig, Khurelbaatar Bilguun, Purevjav Enkhbayar, Hiroki Miyashita, Robert H Kretsinger, Norio Matsushima
Leucine rich repeats (LRRs) are present in over 100,000 proteins from viruses to eukaryotes. The LRRs are 20-30 residues long and occur in tandem. LRRs form parallel stacks of short β-strands and then assume a super helical arrangement called a solenoid structure. Individual LRRs are separated into highly conserved segment (HCS) with the consensus of LxxLxLxxNxL and variable segment (VS). Eight classes have been recognized. Bacterial LRRs are short and characterized by two prolines in the VS; the consensus is xxLPxLPxx with Nine residues (N-subtype) and xxLPxxLPxx with Ten residues (T-subtype)...
April 12, 2018: Protein Journal
Dong Jin Kim, Wook Kim
Purpose: Pre-operative lymph node (LN) size is a valuable parameter for determining treatment strategy for gastric cancer. However, a correlation between LN size and metastasis has not been established. Materials and Methods: Thirty-six LN-positive (LNP) and matched 36 LN-negative (LNN) patients were included, and pathology slides of the LNs of these patients were reviewed. All the LNs were measured along the long-axis (LA) and short-axis (SA), manually. Results: Average retrieved LNs were 37...
March 2018: Journal of Gastric Cancer
Jiyong Gu, Weiwei Lei, Zong Xin, Yi Wu, Lin Peng, Zhibin Li, Zize Feng, Minchan Zhao, Songtao Qi, Yuntao Lu
OBJECTIVE: Fixation with the axis vertebra (C2) using pedicle screws is commonly used to treat an unstable occipitocervical junction; however, it is accompanied by a risk of vertebral artery injury. The occiput-C2 (OC2) crossing translaminar screw fixation technique may avoid this risk, but rod implantation is difficult. Offset connectors can help facilitate this construct. This study aimed to evaluate the stability of a technique for OC2 crossing translaminar screw fixation using offset connectors (C2LAM + OF) in comparison with other methods...
April 3, 2018: Clinical Neurology and Neurosurgery
Shanshan Liang, Fusong Yuan, Xu Luo, Zhuoren Yu, Zhihui Tang
STATEMENT OF PROBLEM: Marginal discrepancy is key to evaluating the accuracy of fixed dental prostheses. An improved method of evaluating marginal discrepancy is needed. PURPOSE: The purpose of this in vitro study was to evaluate the absolute marginal discrepancy of ceramic crowns fabricated using conventional and digital methods with a digital method for the quantitative evaluation of absolute marginal discrepancy. The novel method was based on 3-dimensional scanning, iterative closest point registration techniques, and reverse engineering theory...
April 5, 2018: Journal of Prosthetic Dentistry
Katsuyuki Yamaguchi
INTRODUCTION: The lateral geniculate nucleus (LGN) is the major relay center of the visual pathway in humans. There are few quantitative data on the morphology of LGN in prenatal infants. In this study, using serial brain sections, the author investigated the morphology of this nucleus during the second half of fetal period. MATERIAL AND METHODS: Eleven human brains were obtained at routine autopsy from preterm infants aged 20-39 postmenstrual weeks. After fixation, the brain was embedded en bloc in celloidin and cut serially at 30 μm in the horizontal plane...
April 3, 2018: Neuroscience Letters
Ángeles Malagón-Amor, Luis Miguel Martín-López, David Córcoles, Anna González, Magda Bellsolà, Alan R Teo, Víctor Pérez, Antoni Bulbena, Daniel Bergé
Social withdrawal is a new mental health problem increasingly common, present in different cultures, whose psychopathology and treatment is not yet established. This study aims to determine the socio-demographic and clinical features and possible clinical subtypes that predict the 12-month outcomes of cases with hikikomori syndrome, a severe form of social withdrawal. Socio-demographic and clinical data at baseline were analysed as well as data obtained for 12 months after at-home treatment in 190 cases. The inclusion criteria were: spending all time at home, avoiding social situations and relationships, significant deterioration due to social isolation, with a minimum duration of 6 months...
March 23, 2018: Psychiatry Research
Angel Aleman, Chao Li, Hicham Zaid, Hanna Kindlund, Joshua Fankhauser, Sergey V Prikhodko, Mark S Goorsky, Suneel Kodambaka
Pd(111) thin films, ∼245 nm thick, are deposited on Al2 O3 (0001) substrates at ≈0.5 T m , where T m is the Pd melting point, by ultrahigh vacuum dc magnetron sputtering of Pd target in pure Ar discharges. Auger electron spectra and low-energy electron diffraction patterns acquired in situ from the as-deposited samples reveal that the surfaces are compositionally pure 111-oriented Pd. Double-axis x-ray diffraction (XRD) ω-2θ scans show only the set of Pd 111 peaks from the film. In triple-axis high-resolution XRD, the full width at half maximum intensity Γω of the Pd 111 ω-rocking curve is 630 arc sec...
May 2018: Journal of Vacuum Science & Technology. A, Vacuum, Surfaces, and Films
Valeska Stonawski, Stefan Frey, Yulia Golub, Nicolas Rohleder, Jennifer Kriebel, Tamme W Goecke, Peter A Fasching, Matthias W Beckmann, Johannes Kornhuber, Oliver Kratz, Gunther H Moll, Hartmut Heinrich, Anna Eichler
Epigenetic DNA modifications in genes related to the hypothalamic-pituitary-adrenal (HPA) axis are discussed as a mechanism underlying the association between prenatal depression and altered child HPA activity. In a longitudinal study, DNA methylation changes related to prenatal depressive symptoms were investigated in 167 children aged 6 to 9 years. At six candidate genes, 126 cytosine-guanine dinucleotides were considered without correcting for multiple testing due to the exploratory nature of the study. Further associations with the basal child HPA activity were examined...
April 2, 2018: Development and Psychopathology
Volkan Gelegen, Lut Tamam
OBJECTIVE: Intermittent explosive disorder (IED) is defined as the failure to resist aggressive impulses resulting in repeated acts of verbal and/or physical aggression. Although it is frequently encountered in clinical psychiatric practice, there is a paucity of data concerning IED in the scientific literature both internationally and in Turkey. The aim of this study was to evaluate the prevalence of IED and associated sociodemographic and clinical features in a clinical setting. METHODS: A total of 406 patients who were referred to our psychiatry outpatient clinic for the first time in a six-month period were included in the study...
March 18, 2018: Comprehensive Psychiatry
David J McLaughlin, Kenneth R Hogstrom, Daniel W Neck, John P Gibbons
This study compares energy spectra of the multiple electron beams of individual radiotherapy machines, as well as the sets of spectra across multiple matched machines. Also, energy spectrum metrics are compared with central-axis percent depth-dose (PDD) metrics. METHODS: A lightweight, permanent magnet spectrometer was used to measure energy spectra for seven electron beams (7-20 MeV) on six matched Elekta Infinity accelerators with the MLCi2 treatment head. PDD measurements in the distal falloff region provided R50 and R80-20 metrics in Plastic Water® , which correlated with energy spectrum metrics, peak mean energy (PME) and full-width at half maximum (FWHM)...
March 30, 2018: Journal of Applied Clinical Medical Physics
Ying-Sheng Lin, Wen-Chung Liu, Kuan-Ying Wang, Yaoh-Shiang Lin, Kuo-Chung Yang
OBJECTIVE: To reconstruct extensive head and neck defects usually necessitates double free flaps, which require a time-and-manpower-consuming surgical procedure. We present using a single fibula or peroneal flap with the novel design of obliquely-arranged double skin paddles to reconstruct an extensive head and neck defect. METHODS: From 1998 to 2016, eight patients with the age of 52.25 (35-71) years old had extensive head and neck defects after oral cancer ablation...
March 30, 2018: Microsurgery
Shu-Fei Yang, Virginia Schmied, Elaine Burns, Wendy Brodribb, Yenna Salamonson
BACKGROUND: The Australian Breastfeeding Knowledge and Attitude Questionnaire-Short Form (ABKAQ-SF) was designed to measure breastfeeding knowledge and attitudes of health professionals. To date, a Chinese version of the attitude component of the ABKAQ-SF (ABAQ) is not yet available and has not been cross-validated with nursing students. Research aims: This study aimed to examine (a) the psychometric properties of the ABAQ and (b) group differences and responsiveness of the revised 12-item ABAQ (ABAQ12) among nursing students in Taiwan...
March 1, 2018: Journal of Human Lactation: Official Journal of International Lactation Consultant Association
Michelle A Rensel, Jessica A Ding, Devaleena S Pradhan, Barney A Schlinger
Glucocorticoid (GC) hormones act on the brain to regulate diverse functions, from behavior and homeostasis to the activity of the hypothalamic-pituitary-adrenal axis. Local regeneration and metabolism of GCs can occur in target tissues through the actions of the 11β-hydroxysteroid dehydrogenases [11 beta-hydroxysteroid dehydrogenase type 1 (11β-HSD1) and 11 beta-hydroxysteroid dehydrogenase type 2 (11β-HSD2), respectively] to regulate access to GC receptors. Songbirds have become especially important model organisms for studies of stress hormone action; however, there has been little focus on neural GC metabolism...
2018: Frontiers in Endocrinology
Madlen Stange, Gabriel Aguirre-Fernández, Walter Salzburger, Marcelo R Sánchez-Villagra
BACKGROUND: Morphological convergence triggered by trophic adaptations is a common pattern in adaptive radiations. The study of shape variation in an evolutionary context is usually restricted to well-studied fish models. We take advantage of the recently revised systematics of New World Ariidae and investigate skull shape evolution in six genera of northern Neotropical Ariidae. They constitute a lineage that diversified in the marine habitat but repeatedly adapted to freshwater habitats...
March 27, 2018: BMC Evolutionary Biology
Junsu Lee, Jieun Jeon, Tae-Soo You
Four polar intermetallic compounds belonging to the RE ₂In1- x Li x Ge₂ ( RE = La, Nd, Sm, Gd; x = 0.13(1), 0.28(1), 0.43(1), 0.53(1)) system have been synthesized by the traditional solid-state reaction method, and their crystal structures have been characterized by single-crystal X-ray diffraction (SXRD) analyses. The isotypic crystal structures of four title compounds adopt the Mo₂FeB₂-type structure having the tetragonal space group P4/mbm ( Z = 2, Pearson code tP 40) with three crystallographically independent atomic sites and can be simply described as a pile of the identical 2-dimensioanl (2D) RE ₂In1- x Li x Ge₂ slabs stacked along the c -axis direction...
March 26, 2018: Materials
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