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https://www.readbyqxmd.com/read/27907276/clinical-course-of-methamphetamine-induced-psychotic-disorder-in-a-3-month-follow-up
#1
Sakineh Javadian, Amir Shabani, Seyed Vahid Shariat
Objective: To assess the clinical course of patients with methamphetamine-induced psychotic disorder (MIPD) and any possible predictors of the clinical course in a 3-month follow-up. Methods: This prospective cohort study included 50 patients (7 female, 43 male) with MIPD and was performed from September 2014 to October 2015. Patients were assessed during hospitalization and in a follow-up visit 3 months later. Diagnoses were made using interviews based on the Structured Clinical Interview for DSM-IV Axis I Disorders...
November 3, 2016: Primary Care Companion to CNS Disorders
https://www.readbyqxmd.com/read/27905148/simultaneous-validation-of-five-activity-monitors-for-use-in-adult-populations
#2
C Powell, B P Carson, K P Dowd, A E Donnelly
Numerous cut-points exist to measure physical activity by accelerometry. The ability to compare accelerometer findings from different devices from different locations may be advantageous to researchers. This study aimed to develop and validate cut-points for 1.5, 3, and 6 METs in five activity monitors simultaneously. Fifty-six participants (mean age=39.9 [±11.5] years) performed six activities while wearing a CosMED K4b(2) and five activity monitors: activPAL3 Micro, activPAL, ActiGraph GT1M, ActiGraph wGT3X-BT, and GENEActiv...
December 1, 2016: Scandinavian Journal of Medicine & Science in Sports
https://www.readbyqxmd.com/read/27899069/gastric-dilatation-and-intestinal-obstruction-mimicking-acute-coronary-syndrome-with-dynamic-electrocardiographic-changes
#3
H M M T B Herath, Anne Thushara Matthias, B S D P Keragala, W A E Udeshika, Aruna Kulatunga
BACKGROUND: ST elevation myocardial infarction is a medical emergency and the electrocardiogram is a part of the mainstay in the initial diagnosis. A variety of non-cardiac conditions have been known to mimic the electrocardiographic changes seen in acute coronary syndrome. We present a patient presenting with acute partial intestinal obstruction causing gastric distension and intestinal dilatation who also had dynamic electrocardiographic changes, mimicking anterior ST elevation myocardial infarction...
November 29, 2016: BMC Cardiovascular Disorders
https://www.readbyqxmd.com/read/27897255/high-entropy-metal-diborides-a-new-class-of-high-entropy-materials-and-a-new-type-of-ultrahigh-temperature-ceramics
#4
Joshua Gild, Yuanyao Zhang, Tyler Harrington, Sicong Jiang, Tao Hu, Matthew C Quinn, William M Mellor, Naixie Zhou, Kenneth Vecchio, Jian Luo
Seven equimolar, five-component, metal diborides were fabricated via high-energy ball milling and spark plasma sintering. Six of them, including (Hf0.2Zr0.2Ta0.2Nb0.2Ti0.2)B2, (Hf0.2Zr0.2Ta0.2Mo0.2Ti0.2)B2, (Hf0.2Zr0.2Mo0.2Nb0.2Ti0.2)B2, (Hf0.2Mo0.2Ta0.2Nb0.2Ti0.2)B2, (Mo0.2Zr0.2Ta0.2Nb0.2Ti0.2)B2, and (Hf0.2Zr0.2Ta0.2Cr0.2Ti0.2)B2, possess virtually one solid-solution boride phase of the hexagonal AlB2 structure. Revised Hume-Rothery size-difference factors are used to rationalize the formation of high-entropy solid solutions in these metal diborides...
November 29, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27896469/ct-evaluation-after-neoadjuvant-folfirinox-chemotherapy-for-borderline-and-locally-advanced-pancreatic-adenocarcinoma
#5
Mathilde Wagner, Celia Antunes, Daniel Pietrasz, Christophe Cassinotto, Magaly Zappa, Antonio Sa Cunha, Oliver Lucidarme, Jean-Baptiste Bachet
AIM: To assess anatomic changes on computed tomography (CT) after neoadjuvant FOLFIRINOX (5-fluorouracil/leucovorin/irinotecan/oxaliplatin) chemotherapy for secondary resected borderline resectable (BR) and locally advanced (LA) pancreatic adenocarcinoma and their accuracy to predict resectability and pathological response. METHODS: Thirty-six patients with secondary resected BR/LA pancreatic adenocarcinoma after neoadjuvant FOLFIRINOX chemotherapy (± chemoradiotherapy) were retrospectively included...
November 28, 2016: European Radiology
https://www.readbyqxmd.com/read/27896185/the-relationship-between-the-size-and-the-invasion-depth-of-tumors-in-head-and-neck-cutaneous-squamous-cell-carcinoma
#6
Sam Yong Lee, Won Joo Hwang, Kyung Pil Kim, Hong Min Kim, Jae Ha Hwang, Kwang Seog Kim
BACKGROUND: Cutaneous squamous cell carcinoma (SCC), which occurs in keratinocytes of the epidermis and is the second most common skin cancer, has a more invasive growth pattern and higher potential to metastasize than basal cell carcinoma. Total excision of the primary tumor is the treatment of choice. For clear excision of the tumor, invasion depth is one of the most important factors. This study was conducted to clarify the relationship between the size and the invasion depth of cutaneous SCC...
November 2016: Archives of Plastic Surgery
https://www.readbyqxmd.com/read/27885443/roles-of-the-haustorium-and-endosperm-during-the-development-of-seedlings-of-acrocomia-aculeata-arecaceae-dynamics-of-reserve-mobilization-and-accumulation
#7
Hellen Cássia Mazzottini-Dos-Santos, Leonardo Monteiro Ribeiro, Denise Maria Trombert Oliveira
The mobilization of palm seed reserves is a complex process because of the abundance and diversity of stored compounds and results from the development of a highly specialized haustorium. This work focused on the important Neotropical oleaginous palm Acrocomia aculeata, with the aim of defining phases of seedling development associated with mobilization of reserves and elucidating the role of haustorium and endosperm in this process. Standard methods were performed, including biometric, anatomical, and histochemical analyses, as well as the evaluation of the activities of the enzymes endo-β-mannanase and lipase, throughout the reserve mobilization in seeds during germination and in seedlings...
November 24, 2016: Protoplasma
https://www.readbyqxmd.com/read/27881132/integrated-safety-and-efficacy-analysis-of-once-daily-fluticasone-furoate-for-the-treatment-of-asthma
#8
Paul M O'Byrne, Loretta Jacques, Caroline Goldfrad, Namhee Kwon, Michael Perrio, Louisa J Yates, William W Busse
BACKGROUND: Fluticasone furoate is a once-daily inhaled corticosteroid. This report provides an overview of safety and efficacy data that support the use of once-daily fluticasone furoate 100 μg or 200 μg in adult and adolescent asthma patients. METHODS: Fourteen clinical studies (six Phase II and eight Phase III) were conducted as part of the fluticasone furoate global clinical development programme in asthma. Safety data from 10 parallel-group, randomised, double-blind Phase II and III studies (including 3345 patients who received at least one dose of fluticasone furoate) were integrated to provide information on adverse events, withdrawals, laboratory assessments, vital signs and hypothalamic-pituitary-adrenal axis function...
November 24, 2016: Respiratory Research
https://www.readbyqxmd.com/read/27876804/inbreeding-depression-by-environment-interactions-in-a-free-living-mammal-population
#9
J M Pemberton, P E Ellis, J G Pilkington, C Bérénos
Experimental studies often find that inbreeding depression is more severe in harsh environments, but the few studies of in situ wild populations available to date rarely find strong support for this effect. We investigated evidence for inbreeding depression by environment interactions in nine traits in the individually monitored Soay sheep population of St Kilda, using genomic inbreeding coefficients based on 37 037 single-nucleotide polymorphism loci, and population density as an axis of environmental variation...
November 23, 2016: Heredity
https://www.readbyqxmd.com/read/27876803/association-mapping-for-phenology-and-plant-architecture-in-maize-shows-higher-power-for-developmental-traits-compared-with-growth-influenced-traits
#10
S Bouchet, P Bertin, T Presterl, P Jamin, D Coubriche, B Gouesnard, J Laborde, A Charcosset
Plant architecture, phenology and yield components of cultivated plants have repeatedly been shaped by selection to meet human needs and adaptation to different environments. Here we assessed the genetic architecture of 24 correlated maize traits that interact during plant cycle. Overall, 336 lines were phenotyped in a network of 9 trials and genotyped with 50K single-nucleotide polymorphisms. Phenology was the main factor of differentiation between genetic groups. Then yield components distinguished dents from lower yielding genetic groups...
November 23, 2016: Heredity
https://www.readbyqxmd.com/read/27875874/geometries-of-h2s%C3%A2-mi-m-cu-ag-au-complexes-studied-by-rotational-spectroscopy-the-effect-of-the-metal-atom
#11
Chris Medcraft, Dror M Bittner, David P Tew, Nicholas R Walker, Anthony C Legon
Complexes formed between H2S and each of CuI, AgI, and AuI have been isolated and structurally characterised in the gas phase. The H2S⋯MI complexes (where M is the metal atom) are generated through laser vaporisation of a metal rod in the presence of a low concentration of H2S and CF3I in a buffer gas of argon undergoing supersonic expansion. The microwave spectra of six isotopologues of each of H2S⋯CuI, H2S⋯AgI and three isotopologues of H2S⋯AuI have been measured by chirped-pulse Fourier transform microwave spectroscopy...
November 21, 2016: Journal of Chemical Physics
https://www.readbyqxmd.com/read/27872875/a-comparison-of-the-innate-flexibilities-of-six-chains-in-f1-atpase-with-identical-secondary-and-tertiary-folds-3-active-enzymes-and-3-structural-proteins
#12
Monique M Tirion
The α and β subunits comprising the hexameric assembly of F1-ATPase share a high degree of structural identity, though low primary identity. Each subunit binds nucleotide in similar pockets, yet only β subunits are catalytically active. Why? We re-examine their internal symmetry axes and observe interesting differences. Dividing each chain into an N-terminal head region, a C-terminal foot region, and a central torso, we observe (1) that while the foot and head regions in all chains obtain high and similar mobility, the torsos obtain different mobility profiles, with the β subunits exhibiting a higher motility compared to the α subunits, a trend supported by the crystallographic B-factors...
July 2017: Structural Dynamics (Melville, N.Y.)
https://www.readbyqxmd.com/read/27871100/biomechanical-response-of-military-booted-and-unbooted-foot-ankle-tibia-from-vertical-loading
#13
Frank A Pintar, Michael B Schlick, Narayan Yoganandan, Liming Voo, Andrew C Merkle, Michael Kleinberger
A new anthropomorphic test device (ATD) is being developed by the US Army to be responsive to vertical loading during a vehicle underbody blast event. To obtain design parameters for the new ATD, a series of non-injurious tests were conducted to derive biofidelity response corridors for the foot-ankle complex under vertical loading. Isolated post mortem human surrogate (PMHS) lower leg specimens were tested with and without military boot and in different initial foot-ankle positions. Instrumentation included a six-axis load cell at the proximal end, three-axis accelerometers at proximal and distal tibia, and calcaneus, and strain gages...
November 2016: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/27871092/the-effect-of-rib-shape-on-stiffness
#14
Sven A Holcombe, Stewart C Wang, James B Grotberg
This study investigates the isolated effect of rib shape on the mechanical characteristics of ribs subjected to multiple forms of loading. It aims to measure the variation in stiffness due to shape that is seen throughout the population and, in particular, provide a tool for researchers to better understand the influence of shape on resulting stiffness. A previously published six-parameter shape model of the central axis of human ribs was used. It has been shown to accurately model the overall rib path using intrinsic geometric properties such as size, aspect ratio, and skewness, through shapes based on logarithmic spirals with high curvature continuity...
November 2016: Stapp Car Crash Journal
https://www.readbyqxmd.com/read/27864992/the-mri-bullseye-sign-an-indicator-of-peripheral-nerve-constriction-in-parsonage-turner-syndrome
#15
Darryl B Sneag, Eliana B Saltzman, David W Meister, Joseph H Feinberg, Steve K Lee, Scott W Wolfe
INTRODUCTION: Magnetic resonance imaging's (MRI's) role in identifying hourglass constrictions (HGCs) of nerves in Parsonage-Turner syndrome (PTS) is largely unknown. METHODS: Six patients with PTS and with absent or minimal recovery underwent MRI. Surgical exploration was performed at identified pathologic sites. RESULTS: The time between symptom onset and surgery was 12.4 ± 6.9 months; the time between MRI and surgery was 1.3 ± 0...
November 16, 2016: Muscle & Nerve
https://www.readbyqxmd.com/read/27862873/the-sustained-influence-of-metformin-therapy-on-circulating-glp-1-levels-in-individuals-with-and-without-type-2-diabetes
#16
David Preiss, Adem Dawed, Paul Welsh, Alison Heggie, Angus G Jones, Jacqueline Dekker, Robert Koivula, Tue H Hansen, Ms Caitlin Stewart, Rury R Holman, Paul W Franks, Mark Walker, Ewan R Pearson, Naveed Sattar
AIMS: Small, short studies suggest metformin influences the glucagon-like peptide (GLP)-1 axis in individuals with and without type 2 diabetes (T2DM). In the Carotid Atherosclerosis: Metformin for insulin ResistAnce (CAMERA) trial (NCT00723307) we investigated whether this effect is sustained and related to changes in glycaemia or weight. In the cross-sectional DIabetes REsearCh on patient straTification (DIRECT) study, we investigated basal and post-meal GLP-1 levels in diabetic patients...
November 13, 2016: Diabetes, Obesity & Metabolism
https://www.readbyqxmd.com/read/27855670/influence-of-disruption-of-the-acromioclavicular-and-coracoclavicular-ligaments-on-glenohumeral-motion-a-kinematic-evaluation
#17
Kempland C Walley, Babak Haghpanah, Andreas Hingsammer, Ethan R Harlow, Ashkan Vaziri, Joseph P DeAngelis, Ara Nazarian, Arun J Ramappa
BACKGROUND: Changes to the integrity of the acromioclavicular (AC) joint impact scapulothoracic and clavicular kinematics. AC ligaments provide anterior-posterior stability, while the coracoclavicular (CC) ligaments provide superior-inferior stability and a restraint to scapular internal rotation. The purpose of this cadaveric study was to describe the effect of sequential AC and CC sectioning on glenohumeral (GH) kinematics during abduction (ABD) of the arm. We hypothesized that complete AC ligament insult would result in altered GH translation in the anterior-posterior plane during abduction, while subsequent sectioning of both CC ligaments would result in an increasing inferior shift in GH translation...
November 17, 2016: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/27831889/simple-and-reliable-method-to-estimate-the-fingertip-static-coefficient-of-friction-in-precision-grip
#18
Allan Barrea, David Cordova Bulens, Philippe Lefevre, Jean-Louis Thonnard
The static coefficient of friction (μstatic) plays an important role in dexterous object manipulation. Minimal normal force (i.e. grip force) needed to avoid dropping an object is determined by the tangential force at the fingertip-object contact and the frictional properties of the skin-object contact. Although frequently assumed to be constant for all levels of normal force (NF, the force normal to the contact), μstatic actually varies nonlinearly with NF and increases at low NF levels. No method is currently available to measure the relationship between μstatic and NF easily...
November 2, 2016: IEEE Transactions on Haptics
https://www.readbyqxmd.com/read/27831489/increased-sagittal-vertical-axis-is-associated-with-less-effective-control-of-acute-pain-following-vertebroplasty
#19
Y-C Kim, D H Bok, H-G Chang, S W Kim, M S Park, J K Oh, J Kim, T-H Kim
OBJECTIVES: Although vertebroplasty is very effective for relieving acute pain from an osteoporotic vertebral compression fracture, not all patients who undergo vertebroplasty receive the same degree of benefit from the procedure. In order to identify the ideal candidate for vertebroplasty, pre-operative prognostic demographic or clinico-radiological factors need to be identified. The objective of this study was to identify the pre-operative prognostic factors related to the effect of vertebroplasty on acute pain control using a cohort of surgically and non-surgically managed patients...
November 2016: Bone & Joint Research
https://www.readbyqxmd.com/read/27825860/damage-to-inner-ear-structure-during-cochlear-implantation-correlation-between-insertion-force-and-radio-histological-findings-in-temporal-bone-specimens
#20
Daniele De Seta, Renato Torres, Francesca Yoshie Russo, Evelyne Ferrary, Guillaume Kazmitcheff, Dominique Heymann, Jerome Amiaud, Olivier Sterkers, Daniele Bernardeschi, Yann Nguyen
Cochlear implant insertion should be as least traumatic as possible in order to reduce trauma to the cochlear sensory structures. The force applied to the cochlea during array insertion should be controlled to limit insertion-related damage. The relationship between insertion force and histological traumatism remains to be demonstrated. Twelve freshly frozen cadaveric temporal bones were implanted with a long straight electrodes array through an anterior extended round window insertion using a motorized insertion tool with real-time measurement of the insertion force...
November 4, 2016: Hearing Research
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