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https://www.readbyqxmd.com/read/28213747/bone-morphogenetic-protein-2-for-the-treatment-of-congenital-pseudarthrosis-of-the-tibia-or-persistent-tibial-nonunion-in-children-and-adolescents-a-retrospective-study-with-a-minimum-2-year-follow-up
#1
Tim N Hissnauer, Norbert Stiel, Kornelia Babin, Martin Rupprecht, Michael Hoffmann, Johannes M Rueger, Ralf Stuecker, Alexander S Spiro
There is a lack of studies reporting on rhBMP-2 application in pediatric orthopaedics, although few reports demonstrated promising results of the use of rhBMP-2 in children, especially for spine fusion and for the treatment of congenital pseudarthrosis of the tibia. The objectives of this study were (1) to examine clinical and radiographic healing after rhBMP-2 application for the treatment of congenital pseudarthrosis of the tibia (CPT) or persistent tibial nonunion in children and adolescents, and (2) to investigate the safety of rhBMP-2 use in these cases...
April 2017: Journal of Materials Science. Materials in Medicine
https://www.readbyqxmd.com/read/28207621/mri-based-decision-making-of-implant-removal-in-deep-wound-infection-after-instrumented-lumbar-fusion
#2
Masahiro Kanayama, Tomoyuki Hashimoto, Keiichi Shigenobu, Fumihiro Oha, Akira Iwata, Masaru Tanaka
STUDY DESIGN: A retrospective study. OBJECTIVE: The aim of the study was to review the treatment of deep wound infection after posterior instrumented lumbar fusion, and thereby to optimize the decision-making process of implant removal or retention on the basis of magnetic resonance imaging (MRI) assessment. SUMMARY OF BACKGROUND DATA: Biofilm formed on the surface of the spinal implant prevents infiltration of antibiotics and makes the infection treatment more complicated...
March 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28202380/impact-of-surgical-site-infection-and-surgical-debridement-on-lumbar-arthrodesis-a-single-institution-analysis-of-incidence-and-risk-factors
#3
Timothy Y Wang, Adam G Back, Eliza Hompe, Kevin Wall, Oren N Gottfried
This study identifies the rate of pseudarthrosis following surgical debridement for deep lumbar spine surgical site infection and identify associated risk factors. Patients who underwent index lumbar fusion surgery from 2013 to 2014 were included if they met the following criteria: 1) age >18years, 2) had debridement of deep lumbar SSI, and had 3) lumbar spine AP, lateral and flexion/extension X-rays and computed tomography (CT) at 12months or greater postoperatively. Criteria for fusion included 1) solid posterolateral, facet, or disk space bridging bone, 2) no translational or angular motion on flexion/extension X-rays, and 3) intact posterior hardware without evidence of screw lucency or breakage...
February 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28186473/minimally-invasive-scoliosis-surgery-assisted-by-o-arm-navigation-for-lenke-type-5c-adolescent-idiopathic-scoliosis-a-comparison-with-standard-open-approach-spinal-instrumentation
#4
Weiguo Zhu, Weixiang Sun, Leilei Xu, Xu Sun, Zhen Liu, Yong Qiu, Zezhang Zhu
OBJECTIVE Recently, minimally invasive scoliosis surgery (MISS) was introduced for the correction of adult scoliosis. Multiple benefits including a good deformity correction rate and fewer complications have been demonstrated. However, few studies have reported on the use of MISS for the management of adolescent idiopathic scoliosis (AIS). The purpose of this study was to investigate the outcome of posterior MISS assisted by O-arm navigation for the correction of Lenke Type 5C AIS. METHODS The authors searched a database for all patients with AIS who had been treated with either MISS or PSF between November 2012 and January 2014...
February 10, 2017: Journal of Neurosurgery. Pediatrics
https://www.readbyqxmd.com/read/28185064/smith-robinson-procedure-with-and-without-caspar-plating-as-a-treatment-for-cervical-spondylotic-myelopathy-a-26-year-follow-up-of-23-patients
#5
Benedikt W Burkhardt, Moritz Brielmaier, Karsten Schwerdtfeger, Salam Sharif, Joachim M Oertel
PURPOSE: The purpose of this study was to assess long-term follow-up data after anterior cervical decompression and fusion (ACDF) with and without Caspar plating (ACDF + PS) for the treatment of cervical spondylotic myelopathy (CSM) with special focus on functional outcome, pain, and repeat surgery for adjacent segment disease (ASD). METHOD: Hospital records of 45 patients who were affected by CSM and underwent ACDF or ACDF + PS at least 17 years ago were reviewed...
February 9, 2017: European Spine Journal
https://www.readbyqxmd.com/read/28175580/350%C3%A2-mini-open-transpedicular-corpectomy-and-percutaneous-instrumentation-without-fusion-reoperation-rates-for-implant-failure-and-pseudarthrosis
#6
Darryl Lau, Dean Chou
No abstract text is available yet for this article.
August 1, 2016: Neurosurgery
https://www.readbyqxmd.com/read/28164068/fracture-diaphyseal-femur-in-a-case-of-ipsilateral-excision-arthroplasty-of-hip-report-of-two-cases-with-description-of-an-unusual-injury-pattern-mechanism-and-clinical-decision-making-in-management
#7
Kunal Shah, Tushar Ubale, Rahematullah Abdul, Vaibhav Kasodekar, Ashish Assudani, Kiran Makwana
INTRODUCTION: Although fracture diaphyseal femur is commonly seen in orthopedic practice, its association with ipsilateral resection arthroplasty of hip/pseudarthrosis of neck is rare. The technique of excision arthroplasty has undergone modification with emphasis on preserving as much bone as possible. However, it is not always possible to preserve bone while removing the earlier prosthesis and cement. This often leads to extensive proximal bone loss. Associated ipsilateral fracture femur presents a unique scenario...
September 2016: Journal of Orthopaedic Case Reports
https://www.readbyqxmd.com/read/28155839/a-capsular-based-vascularized-distal-radius-graft-in-treatment-of-proximal-pole-scaphoid-pseudoarthrosis-case-study
#8
Wojciech Sroga, Rosa Ana Perez Giner
We present a possible option for surgical treatment of proximal pole scaphoid pseudarthrosis. We used a vascularized distal radius bone graft that was pedicled on the dorsal capsule of the wrist joint. The publication consists of a case study, conclusions, indications and contraindications for the surgery.
November 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28151779/coxa-vara-in-postseptic-arthritis-of-the-hip-in-children
#9
Ashok N Johari, Aravind Hampannavar, Ratna A Johari, Arjun A Dhawale
The behavior and treatment of coxa vara and pseudarthrosis of the proximal femur secondary to sepsis is not well described. The aim of this study is to describe the pathoanatomy for coxa vara and pseudarthrosis in postseptic hips, evaluate progression of neck shaft angle (NSA), and discuss treatment. This is a retrospective case series of 20 patients (21 hips). There were 11 hips with predominant avascular necrosis of the capital femoral epiphysis without pseudarthrosis (type 1) and 10 with pseudarthrosis (type 2)...
February 1, 2017: Journal of Pediatric Orthopedics. Part B
https://www.readbyqxmd.com/read/28146025/what-is-the-fate-of-pseudarthrosis-detected-1-year-after-anterior-cervical-discectomy-and-fusion
#10
Dong-Ho Lee, Jae Hwan Cho, Chang Ju Hwang, Choon Sung Lee, Samuel K Cho, Chunghwan Kim, Jung-Ki Ha
STUDY DESIGN: Retrospective comparative study. OBJECTIVE: To investigate the consequences and appropriate management of pseudarthrosis after anterior cervical discectomy and fusion (ACDF). SUMMARY OF BACKGROUND DATA: Pseudarthrosis is a frequent complication of ACDF and causes unsatisfactory results. Little is known about long-term prognosis of detecting pseudarthrosis 1 year after ACDF. METHODS: Eighty-nine patients with a minimum 2-year follow-up were included...
January 31, 2017: Spine
https://www.readbyqxmd.com/read/28138771/l5-corpectomy-the-lumbosacral-segmental-geometry-and-clinical-outcome-a-consecutive-series-of-14-patients-and-review-of-the-literature
#11
Martin Vazan, Yu-Mi Ryang, Julia Gerhardt, Felix Zibold, Insa Janssen, Florian Ringel, Jens Gempt, Bernhard Meyer
PURPOSE: We analyzed the lumbosacral segmental geometry and clinical outcome in patients undergoing L5 corpectomy. METHODS: Fourteen consecutive patients who underwent L5 (n = 12) or L4 + 5 (n = 2) corpectomy at our department between January 2010 and April 2015 were included. All patients underwent a baseline physical and neurologic examination on admission. The diagnostic routine included MRI and CT scans and, if possible, an upright X-ray of the lumbar spine before and after surgery...
January 31, 2017: Acta Neurochirurgica
https://www.readbyqxmd.com/read/28116449/-treatment-of-femoral-shaft-fractures-in-children-and-adolescents-%C3%A2-50%C3%A2-kg-a%C3%A2-retrospective-multicenter-trial
#12
M Rapp, R Kraus, P Illing, D W Sommerfeldt, M M Kaiser
BACKGROUND: Operative treatment of diaphyseal fractures of the femur in older children and adolescents remains controversial due to multiple surgical options and higher complication rates in single-center studies compared to younger children. This retrospective multicenter study aimed to register early and late complications in day-by-day treatment. MATERIAL AND METHODS: Sixteen hospitals with particular expertise in pediatric orthopedic trauma participated in this study...
January 23, 2017: Der Unfallchirurg
https://www.readbyqxmd.com/read/28107237/evaluating-a-posterior-approach-for-surgical-treatment-of-thoracolumbar-pseudarthrosis-in-ankylosing-spondylitis
#13
Ting Wang, Dechun Wang, Yanan Cong, Chuqiang Yin, Shuzhong Li, Xiaoliang Chen
STUDY DESIGN: Retrospective study of a posterior approach for surgical treatment of thoracolumbar pseudarthrosis in ankylosing spondylitis (AS). OBJECTIVE: The aim of the current study was to report the surgical results of symptomatic thoracolumbar pseudarthrosis in AS through a posterior approach. SUMMARY OF BACKGROUND DATA: Spinal pseudarthrosis is a well-known complication in AS. The condition may complicate with mechanical back pain, spinal deformity, and sometimes neurological deficits...
February 2017: Clinical Spine Surgery
https://www.readbyqxmd.com/read/28102170/complication-of-a-femoral-fracture-treated-by-intramedullary-nailing-numerical-analysis-of-a-clinical-case
#14
Jakub J Słowiński, Konrad Kudłacik
The aim of this paper is to conduct a numerical analysis of a case of femoral fracture treated by intramedullary nailing and confirm the conditions which led to the formation of a pseudarthrosis at the fracture site. A low-energy femoral fracture was treated by placing a ChFN System intramedullary nail with a derotation pin. Using the finite element method, a bone-implant system was generated which made it possible to observe the displacement area and strains in the region of the fracture gap. The calculations were conducted for 3 variants of the model, using a titanium nail (10 mm and 12 mm) and a steel one (10 mm)...
August 30, 2016: Ortopedia, Traumatologia, Rehabilitacja
https://www.readbyqxmd.com/read/28098740/adult-scoliosis-deformity-surgery-comparison-of-outcomes-between-1-vs-2-attending-surgeons
#15
Jaime A Gomez, Virginie Lafage, Daniel M Scuibba, Shay Bess, Gregory M Mundis, Barthelemy Liabaud, Regina Hanstein, Christopher Shaffrey, Michael Kelly, Christopher Ames, Justin S Smith, Peter G Passias, Thomas Errico, Frank Schwab
STUDY DESIGN: Retrospective review of prospectively collected data. OBJECTIVE: Assess outcomes of adult spinal deformity (ASD) surgery performed by 1 vs. 2 attending surgeons. SUMMARY OF BACKGROUND DATA: ASD centers have developed 2-attending teams in order to improve efficiency; their effects on complications and outcomes have not been reported. METHODS: ASD patients with ≥5 levels fused and > 2-year follow-up were included...
January 16, 2017: Spine
https://www.readbyqxmd.com/read/28089422/low-magnitude-mechanical-signals-and-the-spine-a-review-of-current-and-future-applications
#16
REVIEW
Martin H Pham, Zorica Buser, Jeffrey C Wang, Frank L Acosta
Animal and human studies demonstrate the anabolic properties of low-magnitude mechanical stimulation (LMMS) in its ability to improve bone formation by enhancing the proliferation of mesenchymal stem cells and their subsequent commitment down an osteoblastic lineage. Response to mechanical strains as low as 10μɛ have been seen, illustrating the sensitivity of mechanosensory cells to mechanotransduction pathways. Applications to the spine include treatment of osteoporosis in preparation for instrumented fusion, fracture reduction in spinal cord injury patients to slow bone mineral density loss, and bone tissue engineering and enhancement of bone-implant osseointegration for pseudarthrosis and hardware failure...
January 12, 2017: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/28070823/relationship-between-postoperative-complications-and-fibular-integrity-in-congenital-pseudarthrosis-of-the-tibia-in-children
#17
Yao-Xi Liu, Hai-Bo Mei, Guang-Hui Zhu, Rong-Guo He, Kun Liu, Jin Tang, Jiang-Yan Wu, Wei-Hua Ye, Xin Hu, Qian Tan, An Yan, Sheng-Xiang Huang, Xiao-Qian Tan, Ting Lei
BACKGROUND: This study aimed to investigate the relationship between postoperative complications and fibular integrity in congenital pseudarthrosis of the tibia (CPT) in children. METHODS: A retrospective study was performed in 59 patients with Crawford type IV CPT who were treated with combined surgical technique from 2007 to 2011. The patients were divided into two groups, the CPT with fibular pseudarthrosis (group A) and CPT with intact fibula groups (group B), on the basis of fibula status after the union of CPT...
December 23, 2016: World Journal of Pediatrics: WJP
https://www.readbyqxmd.com/read/28050699/the-challenging-fractures-of-the-odontoid-process-a-review-of-the-classification-schemes
#18
REVIEW
Dimitrios S Korres, Dimitrios G Chytas, Konstantinos N Markatos, Nicolaos E Efstathopoulos, Vasileios S Nikolaou
Fractures of the odontoid process seem to have an unclear and not well-understood behavior. This is well demonstrated in the literature as there is a disagreement in many fields, including the patterns of fractures, the percentage of pseudarthrosis or the appropriate treatment that is required. This situation makes the fracture itself a "challenging" one. Indeed, despite the existence of extensive literature, there are still many unresolved problems concerning these fractures. We recognize six main classification schemes of the odontoid process fractures which clearly demonstrate the presence of differences but, also, the disadvantages that these classifications are related to...
January 3, 2017: European Journal of Orthopaedic Surgery & Traumatology: Orthopédie Traumatologie
https://www.readbyqxmd.com/read/27997507/the-prevalence-and-risk-factors-of-iliac-screw-loosening-after-adult-spinal-deformity-surgery
#19
Tomohiro Banno, Tomohiko Hasegawa, Yu Yamato, Sho Kobayashi, Daisuke Togawa, Shin Oe, Yuki Mihara, Yukihiro Matsuyama
STUDY DESIGN: A retrospective study. OBJECTIVE: We investigated the prevalence of iliac screw loosening and determined risk factors after adult spinal deformity (ASD) surgery. SUMMARY OF BACKGROUND DATA: Lumbosacral fixation is crucial to maintain optimal sagittal alignment. Iliac screws are commonly placed to provide protection for sacral pedicle screws. Radiolucent areas around the screws indicate fixation loss and pseudarthrosis. METHODS: Seventy-two ASD patients (13 men, 59 women; mean age, 69...
December 16, 2016: Spine
https://www.readbyqxmd.com/read/27980226/novel-phenotypes-of-nf1-patients-from-unrelated-chinese-families-with-tibial-pseudarthrosis-and-anemia
#20
Santasree Banerjee, Dongzhu Lei, Shengran Liang, Li Yang, Saijun Liu, Zhu Wei, Jian Ping Tang
Neurofibromatosis type 1 (NF1) is an autosomal dominant, multi-system, neurocutaneous disorder, manifested with neurofibromas and Cafe´-au-lait spots. Germline mutations in NF1 gene are associated with Neurofibromatosis type 1. NF1 gene encodes neurofibromin, a RAS-specific GTPase activating protein. In our study, we present a clinical molecular study of four Chinese probands with NF1 from four unrelated families, showing extreme phenotypic variation with rare phenotype. In family 1, the proband is a 16 months old girl with multiple café-au-lait spots throughout her whole body...
December 14, 2016: Oncotarget
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