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https://www.readbyqxmd.com/read/28922177/project-career-an-individualized-postsecondary-approach-to-promoting-independence-functioning-and-employment-success-among-students-with-traumatic-brain-injuries
#1
Deborah Minton, Eileen Elias, Phillip Rumrill, Deborah J Hendricks, Karen Jacobs, Anne Leopold, Amanda Nardone, Elaine Sampson, Marcia Scherer, Aundrea Gee Cormier, Aiyana Taylor, Caitlin DeLatte
BACKGROUND: Project Career is a five-year interdisciplinary demonstration project funded by NIDILRR. It provides technology-driven supports, merging Cognitive Support Technology (CST) evidence-based practices and rehabilitation counseling, to improve postsecondary and employment outcomes for veteran and civilian undergraduate students with traumatic brain injury (TBI). GOAL: Provide a technology-driven individualized support program to improve career and employment outcomes for students with TBI...
September 14, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28922175/project-career-perceived-benefits-of-ipad-apps-among-college-students-with-traumatic-brain-injury-tbi
#2
K Jacobs, A Leopold, D J Hendricks, E Sampson, A Nardone, K B Lopez, P Rumrill, C Stauffer, E Elias, M Scherer, J Dembe
BACKGROUND: Project Career is an interprofessional five-year development project designed to improve academic and employment success of undergraduate students with a traumatic brain injury (TBI) at two- and four-year colleges and universities. Students receive technology in the form of iPad applications ("apps") to support them in and out of the classroom. OBJECTIVE: To assess participants' perspectives on technology at baseline and perceived benefit of apps after 6 and 12 months of use...
September 14, 2017: Work: a Journal of Prevention, Assessment, and Rehabilitation
https://www.readbyqxmd.com/read/28914003/visual-fatigue-induced-by-viewing-a-tablet-computer-with-a-high-resolution-display
#3
Dong Ju Kim, Chi Yeon Lim, Namyi Gu, Choul Yong Park
PURPOSE: In the present study, the visual discomfort induced by smart mobile devices was assessed in normal and healthy adults. METHODS: Fifty-nine volunteers (age, 38.16 ± 10.23 years; male : female = 19 : 40) were exposed to tablet computer screen stimuli (iPad Air, Apple Inc.) for 1 hour. Participants watched a movie or played a computer game on the tablet computer. Visual fatigue and discomfort were assessed using an asthenopia questionnaire, tear film break-up time, and total ocular wavefront aberration before and after viewing smart mobile devices...
July 18, 2017: Korean Journal of Ophthalmology: KJO
https://www.readbyqxmd.com/read/28898959/cognitive-training-using-a-novel-memory-game-on-an-ipad-in-patients-with-amnestic-mild-cognitive-impairment-amci
#4
George Savulich, Thomas Piercy, Chris Fox, John Suckling, James B Rowe, John T O'Brien, Barbara J Sahakian
Background: Cognitive training is effective in patients with mild cognitive impairment but does not typically address the motivational deficits associated with older populations with memory difficulties. Methods: We conducted a randomized controlled trial of cognitive training using a novel memory game on an iPad in 42 patients with a diagnosis of amnestic mild cognitive impairment assigned to either the cognitive training (n=21; 8 hours of gameplay over 4 weeks) or control (n=21; clinic visits as usual) groups...
August 1, 2017: International Journal of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28893984/nanoswitch-linked-immunosorbent-assay-nlisa-for-fast-sensitive-and-specific-protein-detection
#5
Clinton H Hansen, Darren Yang, Mounir A Koussa, Wesley P Wong
Protein detection and quantification play critical roles in both basic research and clinical practice. Current detection platforms range from the widely used ELISA to more sophisticated, and more expensive, approaches such as digital ELISA. Despite advances, there remains a need for a method that combines the simplicity and cost-effectiveness of ELISA with the sensitivity and speed of modern approaches in a format suitable for both laboratory and rapid, point-of-care applications. Building on recent developments in DNA structural nanotechnology, we introduce the nanoswitch-linked immunosorbent assay (NLISA), a detection platform based on easily constructed DNA nanodevices that change conformation upon binding to a target protein with the results read out by gel electrophoresis...
September 11, 2017: Proceedings of the National Academy of Sciences of the United States of America
https://www.readbyqxmd.com/read/28889977/novel-organelles-with-elements-of-bacterial-and-eukaryotic-secretion-systems-weaponize-parasites-of-drosophila
#6
Mary Ellen Heavner, Johnny Ramroop, Gwenaelle Gueguen, Girish Ramrattan, Georgia Dolios, Michael Scarpati, Jonathan Kwiat, Sharmila Bhattacharya, Rong Wang, Shaneen Singh, Shubha Govind
The evolutionary success of parasitoid wasps, a highly diverse group of insects widely used in biocontrol, depends on a variety of life history strategies in conflict with those of their hosts [1]. Drosophila melanogaster is a natural host of parasitic wasps of the genus Leptopilina. Attack by L. boulardi (Lb), a specialist wasp to flies of the melanogaster group, activates NF-κB-mediated humoral and cellular immunity. Inflammatory blood cells mobilize and encapsulate Lb eggs and embryos [2-5]. L. heterotoma (Lh), a generalist wasp, kills larval blood cells and actively suppresses immune responses...
September 6, 2017: Current Biology: CB
https://www.readbyqxmd.com/read/28883786/arterial-pulsations-cannot-drive-intramural-periarterial-drainage-significance-for-a%C3%AE-drainage
#7
Alexandra K Diem, Matthew MacGregor Sharp, Maureen Gatherer, Neil W Bressloff, Roxana O Carare, Giles Richardson
Alzheimer's Disease (AD) is the most common form of dementia and to date there is no cure or efficient prophylaxis. The cognitive decline correlates with the accumulation of amyloid-β (Aβ) in the walls of capillaries and arteries. Our group has demonstrated that interstitial fluid and Aβ are eliminated from the brain along the basement membranes of capillaries and arteries, the intramural periarterial drainage (IPAD) pathway. With advancing age and arteriosclerosis, the stiffness of arterial walls, this pathway fails in its function and Aβ accumulates in the walls of arteries...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28873865/mobile-app-selection-tool-mast-for-post-secondary-students-with-disabilities
#8
Linda Chmiliar
This paper discusses research examining the use of a Mobile Apps Selection Tool (MAST) designed to facilitate the use of the iPad by post-secondary students with disabilities. MAST is a public website that was developed to support students to become independent in their use of the iPad to meet their learning needs.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28873803/exploring-the-use-of-technology-for-active-aging-and-thriving
#9
Tone Øderud, Elisabeth Østensen, Edith Roth Gjevjon, Anne Moen
The study explores how older adults with limited digital experience become users of tablet computers (iPad) with Internet access, and how the tablet computers become part of their daily life facilitating active aging and thriving. Volunteer adolescents were mobilised to teach and follow up the participants regularly.
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28871024/telemedicine-guided-education-on-secondary-stroke-and-fall-prevention-following-inpatient-rehabilitation-for-texas-patients-with-stroke-and-their-caregivers-a-feasibility-pilot-study
#10
Mansi M Jhaveri, Ruby Benjamin-Garner, Nahid Rianon, Mark Sherer, Gerard Francisco, Farhaan Vahidy, Kayta Kobayashi, Mary Gaber, Paige Shoemake, Kim Vu, Alyssa Trevino, James Grotta, Sean Savitz
INTRODUCTION: The aftermath of stroke leaves many consequences including cognitive deficits and falls due to imbalance. Stroke survivors and families struggle to navigate the complex healthcare system with little assistance posthospital discharge, often leading to early hospital readmission and worse stroke outcomes. Telemedicine Guided Education on Secondary Stroke and Fall Prevention Following Inpatient Rehabilitation feasibility study examines whether stroke survivors and their caregivers find value in telerehabilitation (TR) home visits that provide individualised care and education by a multidisciplinary team after discharge from inpatient rehabilitation...
September 3, 2017: BMJ Open
https://www.readbyqxmd.com/read/28870539/mixed-reality-mr-meets-pharmaceutical-development
#11
W P Forrest, M A Mackey, V M Shah, K M Hassell, P Shah, J L Wylie, J Gopinath, H Balderhaar, L Li, W P Wuelfing, R Helmy
As science evolves, the need for more efficient and innovative knowledge transfer capabilities becomes evident. Advances in drug discovery and delivery sciences have directly impacted the pharmaceutical industry, though the added complexities have not shortened the development process. These added complexities also make it difficult for scientists to rapidly and effectively transfer knowledge to offset the lengthened drug development timelines. While webcams, camera phones and iPads have been explored as potential new methods of real-time information sharing, the non-"hands-free" nature and lack of viewer and observer point-of-view render them unsuitable for the R&D laboratory or manufacturing setting...
September 1, 2017: Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/28862042/the-component-timed-up-and-go-test-the-utility-and-psychometric-properties-of-using-a-mobile-application-to-determine-prosthetic-mobility-in-people-with-lower-limb-amputations
#12
Sheila M Clemens, Robert S Gailey, Christopher L Bennett, Paul F Pasquina, Neva J Kirk-Sanchez, Ignacio A Gaunaurd
OBJECTIVE: Using a custom mobile application to evaluate the reliability and validity of the Component Timed-Up-and-Go test to assess prosthetic mobility in people with lower limb amputation. DESIGN: Cross-sectional design. SETTING: National conference for people with limb loss. SUBJECTS: A total of 118 people with non-vascular cause of lower limb amputation participated. Subjects had a mean age of 48 (±13.7) years and were an average of 10 years post amputation...
August 1, 2017: Clinical Rehabilitation
https://www.readbyqxmd.com/read/28862041/the-use-of-free-non-dementia-specific-apps-on-ipad-to-conduct-group-communication-exercises-for-individuals-with-alzheimer-s-disease-innovative-practice
#13
Anthony Pak-Hin Kong
This study examined the use of various iPad Apps to conduct group cognitive exercises for clients with mild or early stage dementia of Alzheimer's type. A list of free non-dementia-specific Apps suitable for group sessions was compiled. The procedures in choosing these Apps and determining the most successful ones for group exercises were discussed. Based on participants' and professionals' responses to the use of these Apps, the results would render practitioners useful guidelines in replicating and running technology-based training for individuals with dementia...
January 1, 2017: Dementia
https://www.readbyqxmd.com/read/28858221/telemonitoring-via-self-report-and-video-review-in-community-palliative-care-a-case-report
#14
Deidre D Morgan, Kate Swetenham, Timothy H M To, David C Currow, Jennifer J Tieman
Continuous monitoring and management of a person's symptoms and performance status are critical for the delivery of effective palliative care. This monitoring occurs routinely in inpatient settings; however, such close evaluation in the community has remained elusive. Patient self-reporting using telehealth offers opportunities to identify symptom escalation and functional decline in real time, and facilitate timely proactive management. We report the case of a 57-year-old man with advanced non-small cell lung cancer who participated in a telehealth trial run by a community palliative care service...
August 31, 2017: Healthcare (Basel, Switzerland)
https://www.readbyqxmd.com/read/28850380/combat-study-computer-based-assessment-and-treatment-a-clinical-trial-evaluating-impact-of-a-computerized-clinical-decision-support-tool-on-pain-in-cancer-patients
#15
Sunil X Raj, Cinzia Brunelli, Pål Klepstad, Stein Kaasa
BACKGROUND AND AIMS: The prevalence of pain in cancer patients are relatively high and indicate inadequate pain management strategies. Therefore, it is necessary to develop new methods and to improve implementation of guidelines to assess and treat pain. The vast improvement in information technology facilitated development of a computerized symptom assessment and decision support system (CCDS) - the Combat system - which was implemented in an outpatient cancer clinic to evaluate improvement in pain management...
August 8, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28846562/feedback-leads-to-better-exercise-quality-in-adolescents-with-patellofemoral-pain
#16
Henrik Riel, Mark Matthews, Bill Vicenzino, Thomas Bandholm, Kristian Thorborg, Michael Skovdal Rathleff
PURPOSE: Adolescents with patellofemoral pain (PFP) do not comply with their exercise prescription, performing too few and too fast repetitions, compromising recovery. We investigated if real-time feedback on contraction time would improve the ability of adolescents with PFP to perform exercises as prescribed. METHODS: A randomised, controlled, participant-blinded, superiority trial with a 6-week intervention of three weekly sessions of three elastic band exercises was undertaken...
August 25, 2017: Medicine and Science in Sports and Exercise
https://www.readbyqxmd.com/read/28844641/performance-of-an-ipad-application-to-detect-moderate-and-advanced-visual-field-loss-in-nepal
#17
Chris A Johnson, Suman Thapa, Yu Xiang George Kong, Alan L Robin
PURPOSE: To evaluate the accuracy and efficiency of Visual Fields Easy (VFE), a free iPad app, for performing suprathreshold perimetric screening. METHODS: We performed screening visual fields using a calibrated iPad 2 with the VFE application on 206 subjects (411 eyes): 210 normal (NL), 183 glaucoma (GL) and 18 diabetic retinopathy (DR) at Tilganga Institute of Ophthalmology, Kathmandu, Nepal. We correlated the results with a Humphrey Field Analyzer using 24-2 SITA Standard tests on 273 of these eyes (198 NL, 160 GL, 15 DR) RESULTS: The number of missed locations on the VFE correlated with Mean Deviation (MD, r=0...
August 24, 2017: American Journal of Ophthalmology
https://www.readbyqxmd.com/read/28842484/single-domain-antibodies-pinpoint-potential-targets-within-shigella-invasion-plasmid-antigen-d-of-the-needle-tip-complex-for-inhibition-of-type-iii-secretion
#18
Michael L Barta, Jonathan P Shearer, Olivia Arizmendi, Jacqueline M Tremblay, Nurjahan Mehzabeen, Qi Zheng, Kevin P Battaile, Scott Lovell, Saul Tzipori, William D Picking, Charles B Shoemaker, Wendy L Picking
Numerous Gram-negative pathogens infect eukaryotes and use the type III secretion system (T3SS) to deliver effector proteins into host cells. One important T3SS feature is an extracellular needle with an associated tip complex responsible for assembly of a pore-forming translocon in the host cell membrane. Shigella spp. cause shigellosis, also called bacillary dysentery, and invade colonic epithelial cells via the T3SS. The tip complex of Shigella flexneri contains invasion plasmid antigen D (IpaD), which initially regulates secretion and provides a physical platform for the translocon pore...
August 25, 2017: Journal of Biological Chemistry
https://www.readbyqxmd.com/read/28824850/feasibility-and-preliminary-efficacy-of-remotely-delivering-cognitive-training-to-people-with-schizophrenia-using-tablets
#19
Bruno Biagianti, Melissa Fisher, Lisa Howard, Abby Rowlands, Sophia Vinogradov, Joshua Woolley
BACKGROUND: Limited access to Cognitive Training (CT) for people with schizophrenia (SZ) prevents widespread adoption of this intervention. Delivering CT remotely via tablets may increase accessibility, improve scheduling flexibility, and diminish patient burden. METHODS: In this reanalysis of data from a larger trial of CT, we compared two samples of individuals with SZ who chose to complete 40 h of CT either on desktop computers in the laboratory (N = 33) or remotely via iPads (N = 41)...
December 2017: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28819803/if-at-first-you-don-t-succeed%C3%A2-%C3%A2-adoption-of-ipad-marking-for-high-stakes-assessments
#20
Terry Judd, Anna Ryan, Eleanor Flynn, Geoff McColl
Large-scale interview and simulation-based assessments such as objective structured clinical examinations (OSCEs) and multiple mini interviews (MMIs) are logistically complex to administer, generate large volumes of assessment data, and are strong candidates for the adoption of computer-based marking systems. Adoption of new technologies can be challenging, and technical failures, which are relatively commonplace, can delay and/or create resistance to ongoing implementation.This paper reports on the adoption process of an electronic marking system for OSCEs and MMIs following an unsuccessful initial trial...
August 17, 2017: Perspectives on Medical Education
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