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Dogus Hemsinli, Gokalp Altun, Safiye Tuba Kaplan, Furkan Yildirim, Gamze Cebi
INTRODUCTION: Wounds refractory to standard treatment in patients with thromboangiitis obliterans (TAO, Buerger's disease) are associated with amputation, other morbidity and mortality. The purpose of this study was to investigate the effect of hyperbaric oxygen treatment (HBOT) in patients with TAO. MATERIALS AND METHODS: Ninety-seven patients with TAO with ischaemic wounds treated between January 2007 and July 2016 were included in this dual-centre, non-randomised, retrospective study...
March 31, 2018: Diving and Hyperbaric Medicine: the Journal of the South Pacific Underwater Medicine Society
Tuba Bekircan, Ahmet Yaşar, Sercan Yıldırım, Münevver Sökmen, Atalay Sökmen
An efficient in vitro multiplication protocol was designed to Thymus leucotrichus , a subshrub and perennial herb growing naturally in the Northwest of Turkey. Of all basal media studied, Murashige and Skoog medium was found to be superior to the others, providing higher shoot formation and the maximum shoot length. Varying concentrations of cytokinins, i.e., 6-benzyladenine, thidiazuron, 2-isopentenyladenine and kinetin were supplemented in the nutrient media to observe their effects on shoot development and biomass...
March 2018: 3 Biotech
Zaher Nazzal, Hisham Sholi, Suha B Sholi, Mohammad B Sholi, Rawya Lahaseh
BACKGROUND: Mammography screening is an effective tool for early detection and management of breast cancer. Female health-care workers' awareness of breast cancer screening is important because their beliefs and behaviours could influence other women. The aim of this study was to assess mammography screening uptake by female health-care workers at primary health-care centres and to identify the primary motivators and barriers that affect uptake. METHODS: This cross-sectional study included all governmental primary health-care centres in the West Bank...
February 21, 2018: Lancet
Tahir Karaman, Eyyup Altintas, Bekir Eser, Tuba Talo Yildirim, Faruk Oztekin, Alihan Bozoglan
PURPOSE: To determine the effects of age and gender on the color distribution of the right maxillary central, lateral incisors, and canine teeth. MATERIALS AND METHODS: The tooth color was measured using the VITA Easyshade V spectrophotometer with a total of 202 volunteers (89 men, 113 women). The age distribution in this study was between 15 and 70 years old (average: 31). A grey background color was used to prevent background reflection while performing the color measurements...
March 13, 2018: Journal of Prosthodontics: Official Journal of the American College of Prosthodontists
Bahar Güntekin, Lütfü Hanoğlu, Dilan Güner, Nesrin H Yılmaz, Fadime Çadırcı, Nagihan Mantar, Tuba Aktürk, Derya D Emek-Savaş, Fahriye F Özer, Görsev Yener, Erol Başar
Parkinson's disease (PD) is a neurodegenerative disease that is characterized by loss of dopaminergic neurons in the substantia nigra. Mild Cognitive impairment (MCI) and dementia may come along with the disease. New indicators are necessary for detecting patients that are likely to develop dementia. Electroencephalogram (EEG) Delta responses are one of the essential electrophysiological indicators that could show the cognitive decline. Many research in literature showed an increase of delta responses with the increased cognitive load...
2018: Frontiers in Psychology
Deniz Ortaç, Mustafa Cemek, Turan Karaca, Mehmet E Büyükokuroğlu, Zafer Ö Özdemir, Ayşe Tuba Kocaman, Sadık Göneş
CONTEXT: Okra, Abelmoschus esculentus (L.) (Malvaceae), is a medicinal plant widely used in Turkish traditional medicine for the treatment of various diseases such as ulcers and gastritis. OBJECTIVE: In the present study, we evaluated the gastroprotective effect of okra against ethanol-induced acute gastric mucosal injury in animal models. MATERIALS AND METHODS: Wistar rats were treated with 500, 250 or 100 mg/kg okra; 20 mg/kg famotidine (Fam); and 75 mg/kg quercetin (Que)...
December 2018: Pharmaceutical Biology
Hatice Kansu-Celik, Yasemin Tasci, Burcu Kisa Karakaya, Mehmet Cinar, Tuba Candar, Gamze Sinem Caglar
OBJECTIVE: To evaluate the value of maternal serum advanced glycation end products (AGEs) level at 11-13 weeks' gestation for the prediction of preterm labor and or preterm premature rupture of membranes (PPROM). MATERIALS AND METHODS: This prospective cross-sectional study is performed in a university-affiliated hospital between February and April 2016. The participants of this study are low risk pregnant women. Blood samples for maternal AGEs level were collected in the first trimester of pregnancy and all women completed their antenatal follow-up and delivered in our center...
March 5, 2018: Journal of Maternal-fetal & Neonatal Medicine
Mesut Coskun, Tuba Gulsen, Hikmet Koyunbakan
In this note, we solve the inverse nodal problem for Bessel-type p -Laplacian problem [Formula: see text] on a special interval. We obtain some nodal parameters like nodal points and nodal lengths. In addition, we reconstruct the potential function by nodal points. Results obtained in this paper are similar to the classical Sturm-Liouville problem. However, equations of this type are considered with the condition defined at the origin. We solve the problem on the interval [Formula: see text], that problem is not singular...
2018: Journal of Inequalities and Applications
Sawsan Sudqi Said, Guliz Tuba Barut, Nesteren Mansur, Asli Korkmaz, Ayca Sayi-Yazgan
Regulatory B cells (Bregs) play a crucial role in immunological tolerance primarily through the production of IL-10 in many diseases including autoimmune disorders, allergy, infectious diseases, and cancer. To date, various Breg subsets with overlapping phenotypes have been identified. However, the roles of Bregs in Helicobacter infection are largely unknown. In the present study, we investigate the phenotype and function of Helicobacter -stimulated B cells. Our results demonstrate that Helicobacter felis -stimulated IL-10- producing B cells (Hfstim - IL-10+ B) are composed of B10 and Transitional 2 Marginal Zone Precursor (T2-MZP) cells with expression of CD9, Tim-1, and programmed death 1 (PD-1)...
February 26, 2018: Molecular Immunology
Tuba Sarıaydın, Şeref Kerem Çorbacıoğlu, Yunsur Çevik, Emine Emektar
Purpose: This study evaluated whether serum lactate levels (SLL) at admission in patients with cardiac arrest (CA) can predict successful return of spontaneous circulation (ROSC) or short-term survival, especially within the first 24 h. Materials and methods: This prospective, observational study was conducted in the emergency department (ED) of a training and research hospital from April 2015 through February 2016. It included all patients older than 18 years who presented to the ED during the study period with non-traumatic out-of-hospital cardiac arrest (OHCA)...
December 2017: Turkish Journal of Emergency Medicine
Handan Guler, Perihan Cetin, Zeliha Burcu Yurtsal, Busra Cesur, Mine Bekar, Tuba Uçar, Funda Evcili, Ali Cetin
This study assesses the efficacy of simulation-based episiotomy training (SBET) with beef tongue and sponge models in terms of the self confidence of midwifery students while performing episiotomy. Third-year midwifery students from Cumhuriyet University in the fall semesters of 2011 and 2012 were enrolled in the sponge and beef tongue model groups (n = 36 and n = 37, respectively). A checklist was prepared on the required skills for performing episiotomy which can be broken into three main parts, namely preparation, cutting and repairing and completion...
February 9, 2018: Nurse Education in Practice
Suat Biçer, Defne Çöl, Öznur Küçük, Gülay Ç Erdağ, Tuba Giray, Meltem Uğraş, Ayça Vitrinel, Çiğdem Kaspar
BACKGROUND: Acute gastroenteritis is responsible for dehydration in many children. The viruses like rotavirus, norovirus, and adenovirus are considered the main causative agents of gastroenteritis. The goal of this study is the evaluation of the symptoms, clinical findings and hospitalization requirements in pediatric patients with dehydration secondary to viral gastroenteritis. METHODS: The distribution of age, symptoms, clinical and laboratory findings and hospitalization requirements of 156 viral acute gastroenteritis patients with moderate dehydration were evaluated retrospectively...
April 2018: Minerva Pediatrica
Osman Nuri Dilek, Emine Özlem Gür, Turan Acar, Serpil Aydoğmuş
INTRODUCTION: Endometrial cancer is the fourth most common female cancer and also distant metastases to the chest wall associated with these tumors are seen less common. Surgical treatment options for metastases of endometrial cancer are limited. CASE: A 57-year-old patient who underwent total abdominal hysterectomy + bilateral salpingo oophorectomy and received adjuvant chemotherapy for endometrioid-type adenocarcinoma of the endometrium and tuba is presented...
February 12, 2018: Acta Chirurgica Belgica
Ishan Garg, Maria Jose Baladron Zanetti, Ayse Tuba Kendi
Testicular metastasis from gastroesophageal junction (GEJ) adenocarcinoma is a very rare condition. A 57-year-old male with a history of neoadjuvant chemotherapy and surgery for HER-2-positive GEJ adenocarcinoma underwent a follow-up 18F-fluorodeoxyglucose positron emission tomography/computed tomography (PET/CT). It revealed multiple metastases including bilateral testicular and L4 laminar metastasis. The patient received multiple chemotherapies, but follow-up PET/CT showed interval progression of disease...
January 2018: Indian Journal of Nuclear Medicine: IJNM: the Official Journal of the Society of Nuclear Medicine, India
Zeynep Selen Karalok, Birce Dilge Taskin, Zeynep Ozturk, Esra Gurkas, Tuba Bulut Koc, Alev Guven
OBJECTIVE: The objectives of this study were to evaluate the demographic and clinical characteristics, causes, treatment patterns, outcome, and recurrence of childhood peripheral facial palsy. METHODS: We performed a retrospective study of 144 peripheral facial palsy patients, under 18 years old in a tertiary care pediatric hospital. Medical charts were reviewed to analyze the age, gender, side of facial nerve paralysis, family history, cause, grading by the House-Brackmann Facial Nerve Grading Scale (HBS), results of diagnostic tests, therapies, outcomes, and recurrence...
February 9, 2018: Child's Nervous System: ChNS: Official Journal of the International Society for Pediatric Neurosurgery
Ceki Paltura, Tuba Selçuk Can, Behice Kaniye Yılmaz, Mehmet Emre Dinç, Ömer Necati Develioğlu, Mehmet Külekçi
No abstract text is available yet for this article.
February 3, 2018: American Journal of Otolaryngology
Saliha Esenboga, Deniz Çagdas, Tuba T Ozgur, Pınar Gur Çetinkaya, Lutfiye M Turkdemir, Ozden Sanal, Mirjam VanDer Burg, İlhan Tezcan
INTRODUCTION: X-linked agammaglobulinemia is a primary immunodeficiency disorder resulting from BTK gene mutations. There are many studies in the literature suggesting contradictory ideas about phenotype- genotype correlation. OBJECTIVE: The aim of this study was to identify the mutations and clinical findings of patients with XLA in Turkey, to determine long-term complications related to the disease and to analyze the phenotype-genotype correlation. MATERIALS AND METHODS: Thirty-two patients with XLA diagnosed between 1985-2016 in Pediatric Immunology Department of Hacettepe University Ihsan Dogramaci Children's Hospital were investigated...
February 9, 2018: Scandinavian Journal of Immunology
Cansu Arslan Turan, Tuba Cimilli Ozturk, Ebru Unal Akoglu, Rohat Ak, Kemal Aygun, Ali Sahiner, Engin Sumer, Adnan Somay, Ozge Ecmel Onur
Although the mechanism of action is not well known, intravenous lipid emulsion (ILE) has been shown to be effective in the treatment of lipophilic drug intoxications. It is thought that, ILE probably separates the lipophilic drugs from target tissue by creating a lipid-rich compartment in the plasma. The second theory is that ILE provides energy to myocardium with high-dose free fatty acids activating the voltage-gated calcium channels in the myocytes. In this study, effects of ILE treatment on digoxin overdose were searched in an animal model in terms of cardiac side effects and survival...
February 3, 2018: Cardiovascular Toxicology
Irem Dogan Turacli, Haldun Umudum, Arzu Pampal, Tuba Candar, Lara Kavasoglu, Yaren Sari
There is a growing body of evidence about metformin being effective in cancer therapy. Despite controversies about the ways of its effectiveness, several ongoing clinical trials are evaluating the drug when used as an adjuvant or a neo-adjuvant agent. We aimed to investigate metformin's effects on proliferation, metastasis, and hormone receptor expressions in breast cancer cell line MCF-7 incubated in two different glucose conditions. MCF-7 cells were incubated in high or low glucose media and treated with various doses of metformin...
February 3, 2018: Molecular Biology Reports
Mohammad Kazem Hosseini, Tuba Gunel, Ece Gumusoglu, Ali Benian, Kilic Aydinli
Early pregnancy loss (EPL), also termed early miscarriage, is determined as the unintentional expulsion of an embryo or fetus prior to the 12th week of gestation. EPL frequency is ~15% in pregnancies. Fetal development and growth is associate with placental function and vessel development; therefore, the placental genome would represent a useful miscarriage model for (epi)genetic and genomic studies. An important factor of placental development and function is epigenetic regulation of gene expression. microRNAs (miRNAs) are the primary epigenetic regulators which have an important role in placental development and function...
January 31, 2018: Molecular Medicine Reports
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