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https://www.readbyqxmd.com/read/29133097/biological-and-textural-properties-of-underutilized-exudate-gums-of-jammu-and-kashmir-india
#1
Mudasir Bashir, Tuba Usmani, Sundaramoorthy Haripriya, Tanveer Ahmed
Three different exudate gums were studied for their in-vitro antioxidant activity, functional and textural properties. In-vitro antioxidant activity of the gum exudates was evaluated in terms of DPPH radical scavenging, hydroxyl radical scavenging, reducing power and phenolic content assays. Among the gum exudates, almond gum exhibited maximum DPPḢ inhibition of 35.52±1.125% followed by apricot gum and gum arabic at the concentration of 1mg/mL. Gum arabic had significantly higher reducing power than the other exudate gums...
November 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29127120/primary-and-acquired-resistance-to-immune-checkpoint-inhibitors-in-metastatic-melanoma
#2
Tuba N Gide, James S Wilmott, Richard A Scolyer, Georgina V Long
Immune checkpoint inhibitors have revolutionized the treatment of advanced stage metastatic melanoma patients, as well as patients with many other solid cancers, yielding long lasting responses and improved survival. However, a subset of patients who initially respond to immunotherapy, later relapse and develop therapy resistance (termed acquired resistance), while others do not respond at all (termed primary resistance). Primary and acquired resistance are key clinical barriers to further improving outcomes of patients with metastatic melanoma and the known mechanisms underlying them involve various components of the cancer immune cycle, and interactions between multiple signalling molecules and pathways...
November 10, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29101995/acr-appropriateness-criteria-%C3%A2-tinnitus
#3
Marcus M Kessler, Marwan Moussa, Julie Bykowski, Claudia F E Kirsch, Joseph M Aulino, Kevin L Berger, Asim F Choudhri, Terry D Fife, Isabelle M Germano, A Tuba Kendi, Jeffrey H Kim, Michael D Luttrull, Diego Nunez, Lubdha M Shah, Aseem Sharma, Vilaas S Shetty, Sophia C Symko, Rebecca S Cornelius
Tinnitus is the perception of sound in the absence of an external source. It is a common symptom that can be related to hearing loss and other benign causes. However, tinnitus may be disabling and can be the only symptom in a patient with a central nervous system process disorder. History and physical examination are crucial first steps to determine the need for imaging. CT and MRI are useful in the setting of pulsatile tinnitus to evaluate for an underlying vascular anomaly or abnormality. If there is concomitant asymmetric hearing loss, neurologic deficit, or head trauma, imaging should be guided by those respective ACR Appropriateness Criteria(®) documents, rather than the presence of tinnitus...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29079835/circulating-haptoglobin-and-metabolic-syndrome-in-renal-transplant-recipients
#4
Isidor Minović, Michele F Eisenga, Ineke J Riphagen, Else van den Berg, Jenny Kootstra-Ros, Anne-Roos S Frenay, Harry van Goor, Gerald Rimbach, Tuba Esatbeyoglu, Andy P Levy, Carlo Ajm Gaillard, Johanna M Geleijnse, Manfred L Eggersdorfer, Gerjan J Navis, Ido P Kema, Stephan J L Bakker
Haptoglobin (Hp) is an acute phase protein that has recently been linked to components of the metabolic syndrome (MetS). We aimed to evaluate Hp as marker of MetS, and to assess its association with long-term outcome in renal transplant recipients (RTR). We measured plasma Hp in a prospective cohort of 699 stable RTR and 149 healthy controls. Median plasma Hp concentration in RTR was 1.4 [interquartile range (IQR), 1.0-1.8] g/L, which was higher compared to 1.1 [0.9-1.4] g/L in controls (P < 0.001). Hp was independently associated with the MetS (β = 0...
October 27, 2017: Scientific Reports
https://www.readbyqxmd.com/read/29059295/treatment-with-facemask-and-removable-upper-appliance-versus-modified-tandem-traction-bow-appliance-the-effects-on-mandibular-space
#5
Tuba Tortop, Emine Kaygisiz, Safak Erkun, Sema Yuksel
Objective: The aim of this study was to evaluate and compare the mandibular arch posterior space changes in Class III patients treated with facemask (FM) with removable upper appliance or modified tandem traction bow appliance (MTTBA). Methods: Pre- and post-treatment and pre- and post-observation lateral cephalograms of 76 subjects with skeletal and dental Class III malocclusion from the period 2000-10 years formed the materials of this study. In the first group, 25 patients (10 girls, 15 boys; mean age: 10 years, 1 month) were treated with MTTBA...
October 20, 2017: European Journal of Orthodontics
https://www.readbyqxmd.com/read/29057829/association-of-vitamin-e-levels-with-metabolic-syndrome-and-mri-derived-body-fat-volumes-and-liver-fat-content
#6
Sabina Waniek, Romina di Giuseppe, Sandra Plachta-Danielzik, Ilka Ratjen, Gunnar Jacobs, Manja Koch, Jan Borggrefe, Marcus Both, Hans-Peter Müller, Jan Kassubek, Ute Nöthlings, Tuba Esatbeyoglu, Sabrina Schlesinger, Gerald Rimbach, Wolfgang Lieb
We aimed to relate circulating α- and γ-tocopherol levels to a broad spectrum of adiposityrelated traits in a cross-sectional Northern German study. Anthropometric measures were obtained, and adipose tissue volumes and liver fat were quantified by magnetic resonance imaging in 641 individuals (mean age 61 years; 40.6% women). Concentrations of α- and γ-tocopherol were measured using high performance liquid chromatography. Multivariable-adjusted linear and logistic regression were used to assess associations of circulating α- and γ-tocopherol/cholesterol ratio levels with visceral (VAT) and subcutaneous adipose tissue (SAT), liver signal intensity (LSI), fatty liver disease (FLD), metabolic syndrome (MetS), and its individual components...
October 18, 2017: Nutrients
https://www.readbyqxmd.com/read/29051670/effect-of-brewing-conditions-on-antioxidant-properties-of-rosehip-tea-beverage-study-by-response-surface-methodology
#7
Huri İlyasoğlu, Tuba Eda Arpa
The aim of this study was to investigate the effects of brewing conditions (infusion time and temperature) on the antioxidant properties of rosehip tea beverage. The ascorbic acid content, total phenolic content (TPC), and ferric reducing antioxidant power (FRAP) of rosehip tea beverage were analysed. A two-factor and three-level central composite design was applied to evaluate the effects of the variables on the responses. The best quadratic models were obtained for all responses. The generated models were validated under the optimal conditions...
October 2017: Journal of Food Science and Technology
https://www.readbyqxmd.com/read/29047224/ral-signaling-pathway-in-health-and-cancer
#8
REVIEW
Adel Rezaei Moghadam, Elham Patrad, Elham Tafsiri, Warner Peng, Benjamin Fangman, Timothy J Pluard, Anthony Accurso, Michael Salacz, Kushal Shah, Brandon Ricke, Danse Bi, Kyle Kimura, Leland Graves, Marzieh Khajoie Najad, Roya Dolatkhah, Zohreh Sanaat, Mina Yazdi, Naeimeh Tavakolinia, Mohammad Mazani, Mojtaba Amani, Saeid Ghavami, Robyn Gartell, Colleen Reilly, Zaid Naima, Tuba Esfandyari, Faris Farassati
The Ral (Ras-Like) signaling pathway plays an important role in the biology of cells. A plethora of effects is regulated by this signaling pathway and its prooncogenic effectors. Our team has demonstrated the overactivation of the RalA signaling pathway in a number of human malignancies including cancers of the liver, ovary, lung, brain, and malignant peripheral nerve sheath tumors. Additionally, we have shown that the activation of RalA in cancer stem cells is higher in comparison with differentiated cancer cells...
October 18, 2017: Cancer Medicine
https://www.readbyqxmd.com/read/29042742/class-ii-young-adult-treatment-with-twin-force-bite-corrector-10-year-follow-up
#9
Ozge Uslu-Akcam, Ayse Tuba Altug, Ufuk Toygar Memikoglu
One of the most preferred compliance free fixed functional appliances in nongrowing patients is Twin Force Bite corrector (TFBC). The aim of this case report is to evaluate the effectiveness of TFBC in the treatment of an adult Class II case. A 16-year 1-month-old boy having skeletal and dental Class II relationship was selected. Roth 0.018 × 0.025 inch slots brackets were attached; a fixed lingual arch in the mandibular dental arch and a Nance appliance in the maxillary dental arch were used to increase anchorage...
July 2017: Contemporary Clinical Dentistry
https://www.readbyqxmd.com/read/29029989/the-effect-of-demographic-and-disease-variables-on-schneiderian-membrane-thickness-and-appearance
#10
Tuba Talo Yildirim, Güliz Nigar Güncü, Dincer Göksülük, Melek Didem Tözüm, Mehmet Colak, Tolga Fikret Tözüm
OBJECTIVES: The purpose of this study was to evaluate the prevalence of sinus mucosal thickening (MT) and mucosal appearance (MA) in a patient population as detected with cone beam computed tomography (CBCT) and to determine the effects of various disease and demographic factors on MT and MA. STUDY DESIGN: The retrospective study consisted of CBCT images of 1000 maxillary arches in 500 patients. The arches were divided into 3 groups (atrophic, partially atrophic, and nonatrophic) according to the type of the maxillary dental crest...
September 8, 2017: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology
https://www.readbyqxmd.com/read/29025191/essr-consensus-document-for-detection-characterization-and-referral-pathway-for-tumors-and-tumorlike-lesions-of-bone
#11
Radhesh Lalam, Johan L Bloem, Iris M Noebauer-Huhmann, Klaus Wörtler, Alberto Tagliafico, Filip Vanhoenacker, Violeta Vasilevska Nikodinovska, Hatice Tuba Sanal, Henk-Jan van der Woude, Olympia Papakonstantinou, Gunnar Åström, Mark Davies, Amanda Isaac, Marc-André Weber
No abstract text is available yet for this article.
November 2017: Seminars in Musculoskeletal Radiology
https://www.readbyqxmd.com/read/29024754/comparison-of-genetic-characteristics-of-canine-papillomaviruses-in-turkey
#12
Tuba Çiğdem Oğuzoğlu, Mehmet Özkan Timurkan, Bahattin Taylan Koç, Feray Alkan
Papillomavirus (PV) infections often cause benign and malignant skin neoplasia in dogs. To date, twenty types of canine papillomaviruses (CPVs) have been described worldwide. A detailed molecular characterization of CPVs in Turkey is lacking. In the present study, oral and mucosal lesions from 13 dogs with suspected CPV infection from the Mediterranean and central Anatolian regions of Turkey were analyzed. The partial gene sequences of the L1, E6, and E7 regions were compared with those of CPV types in the GenBank database...
October 9, 2017: Infection, Genetics and Evolution
https://www.readbyqxmd.com/read/29023312/prediction-of-descemet-membrane-perforation-during-deep-anterior-lamellar-keratoplasty-in-patients-with-keratoconus-with-stromal-scar
#13
Mehmet Cuneyt Ozmen, Nilufer Yesilirmak, Bahri Aydin, Kubra Serbest Ceylanoglu, Hatice Tuba Atalay, Fikret Akata
OBJECTIVES: To report big-bubble deep anterior lamellar keratoplasty (DALK) in patients with keratoconus with corneal stromal scar, and to investigate factors that can influence intraoperative Descemet membrane (DM) perforation. METHODS: A retrospective study included patients with keratoconus with central stromal scar that underwent DALK using the big-bubble technique. Best spectacle-corrected visual acuity (BSCVA), keratometry, minimum corneal thickness (MCT), stromal scar depth, and endothelial cell density (ECD) were recorded...
October 11, 2017: Eye & Contact Lens
https://www.readbyqxmd.com/read/29023142/diffusion-weighted-imaging-in-ectopic-pregnancy-ring-of-restriction-sign
#14
Afak Durur-Karakaya, Mehmet Seker, İrmak Durur-Subasi
OBJECTIVE: To demonstrate the diffusion-weighted imaging (DWI) findings of ectopic pregnancy (EP) and introduce the "ring of restriction" sign by discussing possible causes. METHODS: Between January 2014 and January 2017, patients with EP and examined by MRI on a 3T scanner were retrospectively evaluated. MRI and DWI findings were recorded. RESULTS: A total of 40 patients were diagnosed with EP at our university hospital, 8 of whom (20%) were evaluated by MRI and DWI...
October 27, 2017: British Journal of Radiology
https://www.readbyqxmd.com/read/28985397/a-rare-cause-of-torticollis-grisel-syndrome
#15
Nukhet Aladag Ciftdemir, Tuba Eren, Mert Ciftdemir
Painful torticollis in children requires specific attention. Grisel syndrome is diagnosed on suspicion in patients with recent or history of ongoing upper respiratory tract infections and in patients with restriction of movement or deformity following oto-rhino-laryngologic surgery. Pediatricians should be aware of this condition because early diagnosis and intervention are critical for prognosis in Grisel syndrome.
July 18, 2017: Journal of Tropical Pediatrics
https://www.readbyqxmd.com/read/28984336/a-retrospective-evaluation-of-the-epithelial-changes-lesions-and-neoplasms-of-the-gallbladder-in-turkey-and-a-review-of-the-existing-sampling-methods-a-multicentre-study
#16
Güldal Esendağlı, F Göknur Akarca, Serdar Balcı, Asuman Argon, Selma Şengiz Erhan, Nesrin Turhan, Neslihan İnce Zengin, Sevinç Hallaç Keser, Betül Çelik, Tangül Bulut, Samir Abdullazade, Esra Erden, Berna Savaş, Temmuz Bostan, Özgül Sağol, Anıl Aysal Ağalar, Nuray Kepil, Yıldırım Karslıoğlu, Armağan Günal, Fatma Markoç, Burcu Saka, Gonca Özgün, Şükrü Oğuz Özdamar, Burak Bahadır, Esin Kaymaz, Emre Işık, Semin Ayhan, Deniz Tunçel, Banu Özgüven Yılmaz, Sevinç Çelik, Tuba Karabacak, İpek Erbarut Seven, Çiğdem Ataizi Çelikel, Zuhal Gücin, Özgür Ekinci, Gülen Akyol
OBJECTIVE: As there is continuing disagreement among the observers on the differential diagnosis between the epithelial changes/lesions and neoplasms of the gallbladder, this multicentre study was planned in order to assess the rate of the epithelial gallbladder lesions in Turkey and to propose microscopy and macroscopy protocols. MATERIAL AND METHOD: With the participation of 22 institutions around Turkey that were included in the Hepato-Pancreato-Biliary Study Group, 89,324 cholecystectomy specimens sampled from 2003 to 2016 were retrospectively evaluated...
October 6, 2017: Türk Patoloji Dergisi
https://www.readbyqxmd.com/read/28976139/cystic-lymphangioma-of-the-lesser-omentum-in-a-pregnant-woman-a-case-report-and-review-of-the-literature
#17
Ozhan Ozdemir, Mustafa Erkan Sarı, Cemal Resat Atalay, Yüksel Kurban, Vusale Asgarova, Devrim Tuba Unal
Lymphangiomas are rare benign tumors which are generally seen in pediatric population and the etiopathogenesis has not yet been understood. They occasionally occur in the head and neck or axillary region with only 5% of them being located in the abdominal or mediastinal cavity. These tumors may be asymptomatic or may cause acute abdominal symptoms due to the location and extention. In the English literature, only 4 cases of lymphangioma were reported to have occurred in the pregnancy period. Herein, we report a case of cystic lymphangioma of the lesser omentum detected incidentally on the ultrasonogram of a 21 year-old, 26-week pregnant woman...
September 2017: Journal of Experimental Therapeutics & Oncology
https://www.readbyqxmd.com/read/28974371/predictors-of-false-negative-diffusion-weighted-mri-in-clinically-suspected-central-cause-of-vertigo
#18
Ebru Unal Akoglu, Haldun Akoglu, Tuba Cimilli Ozturk, Bahaeddin Onur, Serkan Emre Eroglu, Ozge Onur, Arzu Denizbasi
INTRODUCTION: Vertigo is classified as peripheral and central. Differentiation of stroke mimics is the most important diagnostic challenge. There is no clinical guidance for the indications of neuroimaging in isolated vertigo patients. The primary aim of this study is to test the diagnostic value of a DWI-MRI protocol to rule-out a central cause in patients with acute isolated vertigo in the ED. METHODS: We prospectively enrolled 144 patients who were presented with isolated vertigo to the ED...
September 23, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28971180/an-infrequent-case-of-intussusception-caused-by-gastrointestinal-stromal-tumor-in-an-adult-patient
#19
Mehmet Mahir Fersahoglu, Ayse Tuba Fersahoglu, Nuriye Esen Bulut, Burcu Seher Anil Narin, Sinan Tezer
Intussusception may occur anywhere in the gastrointestinal system. Unlike its idiopathic childhood counterpart, it is uncommon during adult life and a definitive cause is usually found; almost half of cases develop with malignancy. Gastrointestinal stromal tumors (GIST) originate from interstitial Cajal cells of the gastrointestinal tract. They more frequently occur in the stomach and small intestines, and often grow extraluminally, making it unlikely to cause an obstruction or bleeding. Presently described is an unusual instance of ileo-ileal intussusception due to GIST...
2017: Northern Clinics of Istanbul
https://www.readbyqxmd.com/read/28971154/value-of-plasma-neutrophil-gelatinase-associated-lipocalin-ngal-in-distinguishing-between-acute-kidney-injury-aki-and-chronic-kidney-disease-ckd
#20
Seref Kerem Corbacıoglu, Yunsur Cevik, Emine Akinci, Hüseyin Uzunosmanoglu, Seda Dagar, Tuba Safak, Veysel Oncul, Murat Guvendi
OBJECTIVE: In this study, we aimed to determine whether plasma NGAL levels could be used as a biomarker for distinguishing between AKI and CKD in emergency medicine. MATERIALS AND METHODS: This prospective study was conducted at the ED of a training and research hospital over a six-month period in 2015. Three groups were defined: an AKI group - defined as a new onset of at least a 1.5-fold or ≥0.3 mg increment increase of SCr values from the normal baseline, a stable CKD group - only included presence of stages 2 through 4 of CKD according to the National Kidney Foundation's KDIGO 2012, and a control group...
September 2017: Turkish Journal of Emergency Medicine
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