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https://www.readbyqxmd.com/read/28098108/the-relationship-between-mean-platelet-volume-and-neutrophil-lymphocyte-ratio-with-inflammation-and-proteinuria-in-chronic-kidney-disease
#1
Gulay Yilmaz, Can Sevinc, Sedat Ustundag, Yasemin Coskun Yavuz, Tuba Hacıbekiroglu, Esra Hatipoglu, Mehmet Baysal
Atherosclerosis, which develops as a result of inflammation, is the most important cause of morbidity and mortality in chronic kidney disease (CKD). In this study, we investigated the relationship of mean platelet volume (MPV) and neutrophil/lymphocyte ratio (NLR) with inflammation and proteinuria in patients with CKD Stage 3-4. Healthy individuals who applied to nephrology clinic for checkup purposes acted as controls. Fifty-three patients and 30 healthy controls were included in the study. Patients with diabetes mellitus, active infection, malignancy, and coronary artery disease were excluded from the study...
January 2017: Saudi Journal of Kidney Diseases and Transplantation
https://www.readbyqxmd.com/read/28081354/is-there-a-difference-between-parkinson-disease-patients-and-a-control-group-in-terms-of-urinary-symptoms-and-quality-of-life
#2
Erdal Benli, Fahriye Feriha Özer, Yasemin Kaya, Tuba Şaziye Özcan, Ali Ayyıldız
BACKGROUND/AIM: The aim of this study is to research whether urinary symptoms and disruption of quality of life observed in Parkinson disease patients are different than those of their healthy peers. Additionally, whether these complaints were affected by characteristics such as age at onset of Parkinson disease, sex, disease duration, and severity was investigated. MATERIALS AND METHODS: This study comprised a total of 79 individuals, 39 Parkinson patients and a control group of 40 individuals...
December 20, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/28079847/relationship-between-abnormalities-on-high-resolution-computerized-tomography-pulmonary-function-and-bronchoalveolar-lavage-in-progressive-systemic-sclerosis
#3
Gulfidan Cakmak, Tuba Selcuk Can, Sule Gundogdu, Canan Akman, Hande Ikitimur, Benan Musellim, Gul Ongen
:  Introduction and aim: Progressive systemic sclerosis (pSS) is a multisystemic connective tissue disease characterized by fibrosis of the skin and internal organs including lung. The mechanisms that leads to progressive lung fibrosis in scleroderma remain obscure. In this study, we aimed to investigate the correlation between HRCT findings and patients' clinical and functional status and the degree of alveolitis based on the BAL resultsMaterials and methods: 65 patients with pSS were evaluated...
December 23, 2016: Sarcoidosis, Vasculitis, and Diffuse Lung Diseases: Official Journal of WASOG
https://www.readbyqxmd.com/read/28076413/dynamic-characteristics-of-ventilatory-and-gas-exchange-during-sinusoidal-walking-in-humans
#4
Yoshiyuki Fukuoka, Masaaki Iihoshi, Juhelee Tuba Nazunin, Daijiro Abe, Yoshiyuki Fukuba
Our present study investigated whether the ventilatory and gas exchange responses show different dynamics in response to sinusoidal change in cycle work rate or walking speed even if the metabolic demand was equivalent in both types of exercise. Locomotive parameters (stride length and step frequency), breath-by-breath ventilation (V̇E) and gas exchange (CO2 output (V̇CO2) and O2 uptake (V̇O2)) responses were measured in 10 healthy young participants. The speed of the treadmill was sinusoidally changed between 3 km·h-1 and 6 km·h-1 with various periods (from 10 to 1 min)...
2017: PloS One
https://www.readbyqxmd.com/read/28069739/a-two-tiered-mechanism-enables-localized-cdc42-signaling-during-enterocyte-polarization
#5
Lucas J M Bruurs, Susan Zwakenberg, Mirjam C van der Net, Fried J Zwartkruis, Johannes L Bos
Signaling by the small GTPase Cdc42 governs a diverse set of cellular processes that contribute to tissue morphogenesis. Since these processes often require highly localized signaling, Cdc42 activity must be clustered in order to prevent ectopic signaling. During cell polarization, apical Cdc42 signaling directs the positioning of the nascent apical membrane. However, the molecular mechanisms that drive Cdc42 clustering during polarity establishment are largely unknown.Here we demonstrate that during cell polarization localized Cdc42 signaling is enabled via activity-dependent control of Cdc42 mobility...
January 9, 2017: Molecular and Cellular Biology
https://www.readbyqxmd.com/read/28069301/future-water-availability-in-the-largest-freshwater-mediterranean-lake-is-at-great-risk-as-evidenced-from-simulations-with-the-swat-model
#6
Tuba Bucak, Dennis Trolle, Hans Estrup Andersen, Hans Thodsen, Şeyda Erdoğan, Eti E Levi, Nur Filiz, Erik Jeppesen, Meryem Beklioğlu
Inter- and intra-annual water level fluctuations and changes in water flow regime are intrinsic characteristics of Mediterranean lakes. Additionally, considering climate change projections for the water-limited Mediterranean region, increased air temperatures and decreased precipitation are anticipated, leading to dramatic declines in lake water levels as well as severe water scarcity problems. The study site, Lake Beyşehir, the largest freshwater lake in the Mediterranean basin, is - like other Mediterranean lakes - threatened by climatic changes and over-abstraction of water for irrigated crop farming...
January 6, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28064085/cortisol-awakening-response-is-blunted-and-pain-perception-is-increased-during-menses-in-cyclic-women
#7
Tuba Ozgocer, Cihat Ucar, Sedat Yildiz
BACKGROUND AND AIMS: The incidence of menstrual symptoms is reported to be as high as 90% in cyclic women. These symptoms, including anxiety and pain, might be associated with cortisol, as its receptors are widely distributed in the brain areas associated with behavior. Therefore, the current study aimed to assess the cortisol awakening response (CAR) throughout the menstrual cycle and correlate it with pain perception and trait anxiety. MATERIALS AND METHODS: CAR was assessed by measuring salivary cortisol at 0, 15, 30, and 60min following awakening in the same women (n=59, age 22...
December 21, 2016: Psychoneuroendocrinology
https://www.readbyqxmd.com/read/28058158/a-rare-cause-of-proptosis-in-childhood-langerhans-cell-histiocytosis
#8
Mustafa Vatansever, Esra Vatansever, Erdem Dinç, Ayça Sarı, Tuba Kara
A three-year-old male patient was admitted to the clinic with proptosis in his right eye. He had a history of fever with an unknown etiology. In examination, right proptosis was observed and an immobile mass was palpated at the lateral wall of the right orbita. Eye movement was unrestricted in all directions and anterior and posterior segment examination was normal in both eyes. On computed tomography, diffuse bone destruction and expansion was observed in the right orbital lateral wall and other cranial bones...
August 2016: Turkish Journal of Ophthalmology
https://www.readbyqxmd.com/read/28039992/perceptually-salient-spectrotemporal-modulations-for-recognition-of-sustained-musical-instruments
#9
Etienne Thoret, Philippe Depalle, Stephen McAdams
Modulation Power Spectra include dimensions of spectral and temporal modulation that contribute significantly to the perception of musical instrument timbres. Nevertheless, it remains unknown whether each instrument's identity is characterized by specific regions in this representation. A recognition task was applied to tuba, trombone, cello, saxophone, and clarinet sounds resynthesized with filtered spectrotemporal modulations. The most relevant parts of this representation for instrument identification were determined for each instrument...
December 2016: Journal of the Acoustical Society of America
https://www.readbyqxmd.com/read/28026992/sesquiterpene-lactone-composition-and-cellular-nrf2-induction-of-taraxacum-officinale-leaves-and-roots-and-taraxinic-acid-%C3%AE-d-glucopyranosyl-ester
#10
Tuba Esatbeyoglu, Betina Obermair, Tabea Dorn, Karsten Siems, Gerald Rimbach, Marc Birringer
Taraxacum officinale, the common dandelion, is a plant of the Asteraceae family, which is used as a food and medical herb. Various secondary plant metabolites such as sesquiterpene lactones, triterpenoids, flavonoids, phenolic acids, coumarins, and steroids have been described to be present in T. officinale. Dandelion may exhibit various health benefits, including antioxidant, anti-inflammatory, and anticarcinogenic properties. We analyzed the leaves and roots of the common dandelion (T. officinale) using high-performance liquid chromatography/mass spectrometry to determine its sesquiterpene lactone composition...
January 2017: Journal of Medicinal Food
https://www.readbyqxmd.com/read/28013184/variables-determining-mortality-in-patients-with-acinetobacter-baumannii-meningitis-ventriculitis-treated-with-intrathecal-colistin
#11
Bahadır Ceylan, Ferhat Arslan, Oguz Resat Sipahi, Mustafa Sunbul, Bahar Ormen, İsmail N Hakyemez, Tuba Turunc, Yeşim Yıldız, Hasan Karsen, Gul Karagoz, Recep Tekin, Burcu Hizarci, Vedat Turhan, Sebnem Senol, Nefise Oztoprak, Mesut Yılmaz, Kevser Ozdemir, Sinan Mermer, Omer F Kokoglu, Ali Mert
AIM: To examine the variables associated with mortality in patients with Acinetobacter baumannii-related central nervous system infections treated with intrathecal colistin. MATERIALS AND METHODS: This multi-centre retrospective case control study included patients from 11 centres in Turkey, as well as cases found during a literature review. Only patients with CNS infections caused by multidrug-resistant or extensively drug-resistant Acinetobacter baumannii treated with intrathecal colistin were included in this study...
December 14, 2016: Clinical Neurology and Neurosurgery
https://www.readbyqxmd.com/read/28011972/four-cases-with-kawasaki-disease-and-viral-infection-aetiology-or-association
#12
Tuba Giray, Suat Biçer, Öznur Küçük, Defne Çöl, Zerrin Yalvaç, Yeşim Gürol, Gülden Yilmaz, Ahmet Saç, Yigit Mogol
The aetiology of Kawasaki disease has not yet been precisely determined. It has been associated with a variety of bacterial and viral agents. Some viruses including human adenovirus, coronavirus, and parainfluenza virus type 3 have been isolated from patients with Kawasaki disease. Clinical presentation of patients with human coronavirus and adenovirus infections mimics Kawasaki disease. In addition, these viruses may also be detected in Kawasaki disease as a coinfection. In this report, we present four Kawasaki disease patients infected with adenovirus, coronavirus OC43/HKU1 and parainfluenza virus type 3...
1, 2016: Le Infezioni in Medicina
https://www.readbyqxmd.com/read/27997351/the-prevalence-of-dyslipidemia-and-associated-factors-in-children-and-adolescents-with-type-1-diabetes
#13
Tuba Bulut, Fatma Demirel, Ayşe Metin
BACKGROUND: Dyslipidemia increases the frequency and severity of micro and macrovascular complications of type 1 diabetes (T1D). The present study aims to determine the prevalence of dyslipidemia and its association with clinical and laboratory findings in diabetic children and adolescents. METHODS: The study included 202 children and adolescents with T1D. Demographic data and laboratory findings were obtained from patients files. RESULTS: Dyslipidemia prevalence was found to be 26...
December 20, 2016: Journal of Pediatric Endocrinology & Metabolism: JPEM
https://www.readbyqxmd.com/read/27992883/the-vibrio-cholerae-minor-pilin-tcpb-initiates-assembly-and-retraction-of-the-toxin-coregulated-pilus
#14
Dixon Ng, Tony Harn, Tuba Altindal, Subramania Kolappan, Jarrad M Marles, Rajan Lala, Ingrid Spielman, Yang Gao, Caitlyn A Hauke, Gabriela Kovacikova, Zia Verjee, Ronald K Taylor, Nicolas Biais, Lisa Craig
Type IV pilus (T4P) systems are complex molecular machines that polymerize major pilin proteins into thin filaments displayed on bacterial surfaces. Pilus functions require rapid extension and depolymerization of the pilus, powered by the assembly and retraction ATPases, respectively. A set of low abundance minor pilins influences pilus dynamics by unknown mechanisms. The Vibrio cholerae toxin-coregulated pilus (TCP) is among the simplest of the T4P systems, having a single minor pilin TcpB and lacking a retraction ATPase...
December 2016: PLoS Pathogens
https://www.readbyqxmd.com/read/27979226/fractionation-enzyme-inhibitory-and-cellular-antioxidant-activity-of-bioactives-from-purple-sweet-potato-ipomoea-batatas
#15
Tuba Esatbeyoglu, Miriam Rodríguez-Werner, Anke Schlösser, Peter Winterhalter, Gerald Rimbach
Sweet potato (Ipomoea batatas L.) is mainly cultivated in Asia. The deep purple color of purple sweet potato (PSP) is due to the high content of acylated anthocyanins. In the present study, PSP-derived polyphenols were identified using HPLC-PDA and HPLC-ESI-MS(n) analyses. After concentration of the polyphenols from PSP, preparative separation into two fractions, designated anthocyanins (AF) and copigments (CF), was carried out using adsorptive membrane chromatography. In enzyme inhibitory assays, all PSP samples inhibited the enzymes α-amylase, α-glucosidase and xanthine oxidase...
April 15, 2017: Food Chemistry
https://www.readbyqxmd.com/read/27976564/nasal-chondromesenchymal-hamartoma-a-rare-pediatric-tumor-case-report
#16
Adnan Ünal, Rauf Oğuzhan Kum, Yonca Avcı, Devrim Tuba Ünal
Nasal chondromesenchymal hamartoma has characteristic clinicopathological features and it is accepted as the upper airway analogue of mesenchymal hamartoma of the chest wall. It is a rare lesion and only 31 cases have been reported in the English literature until 2014. In this article, a 13-year-old nasal chondromesenchymal hamartoma case is presented, which is the first nasal chondromesenchymal hamartoma case from Turkey. Although, nasal chondromesenchymal hamartoma has been accepted as a benign lesion, the possibility of malignant transformation should be kept in mind, and detailed histologic examination should be performed particularly in adult nasal chondromesenchymal hamartoma cases...
2016: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/27973678/clinical-feasibility-of-xbox-kinecttm-training-for-stroke-rehabilitation-a-single-blind-randomized-controlled-pilot-study
#17
Tuba Alışkan Türkbey, Sehim Kutlay, Haydar Gök
OBJECTIVE: To evaluate the feasibility and safety of Xbox KinectTM training of the upper extremity in subacute stroke rehabilitation. DESIGN: A single-blind, randomized controlled, pilot study. PATIENTS: Twenty consecutive patients with stroke. METHODS: Participants were allocated randomly to 2 groups: the control group received conventional therapy and the experimental group received additional Xbox KinectTM training for 20 sessions...
January 19, 2017: Journal of Rehabilitation Medicine
https://www.readbyqxmd.com/read/27966305/efficacy-of-mitomycin-c-and-infliximab-in-reducing-adhesionand-fibrosis-following-strabismus-surgery
#18
Emin Serbülent Güçlü, Ayşe Ayça Sarı, Erdem Dinç, Tuba Özcan Metin, Banu Çoşkun Yılmaz, Bahar Taşdelen
BACKGROUND/AIM: The present study aimed to investigate the efficacy of mitomycin-C (MMC) and infliximab (INF) in reducing adhesion and fibrosis following strabismus surgery. MATERIALS AND METHODS: Forty eyes of 20 albino rabbits were separated into MMC and INF groups. Right and left eyes of rabbits were assigned to the drug and control groups, respectively. The superior rectus muscle was disinserted, the drug was administered to the surgical area for 5 min in the drug eyes (MMC 0...
November 17, 2016: Turkish Journal of Medical Sciences
https://www.readbyqxmd.com/read/27957371/a-rare-cause-of-nasal-obstruction-metastatic-renal-cell-carcinoma
#19
Tuba Dilay Kokenek-Unal, B Gumuskaya, B Ocal, Murat Alper
Introduction. Renal cell carcinoma can present with several interesting symptoms, paraneoplastic syndromes, and unusual metastatic sites. Head and neck region is one of the rare locations for renal cell carcinoma metastasis. Case Report. A 50-year-old man was admitted to the hospital with nasal congestion and snoring. Physical examination revealed nasal serous secretion. First taken biopsy was misinterpreted. The symptoms of the patient were not revealed and he was readmitted to the hospital. On radiologic examination, a vascular rich mass in maxillary sinus extending to the nasal cavity was observed...
2016: Case Reports in Pathology
https://www.readbyqxmd.com/read/27956863/inhibitory-effect-of-lactococcin-bz-against-listeria-innocua-and-indigenous-microbiota-of-fresh-beef
#20
Zeliha Yıldırım, Sabire Yerlikaya, Nilgün Öncül, Tuba Sakin
In this study, the effect of lactococcin BZ on microbiological quality of fresh beef is investigated. For this purpose, the meat samples were treated with various amounts of lactococcin BZ (200-2500 AU/mL), a bacteriocin produced by Lactococcus lactis spp. lactis BZ, and kept at 4-5 °C for 12 days. During storage, the microbiological properties of the meat samples with or without lactococcin BZ were determined. Inhibitory effect of lactococcin BZ depended on its amount. The higher the amount of lactococcin BZ, the higher the inhibitory activity...
September 2016: Food Technology and Biotechnology
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