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https://www.readbyqxmd.com/read/29341012/biomedical-19f-mri-using-perfluorocarbons
#1
Tuba Güden-Silber, Sebastian Temme, Christoph Jacoby, Ulrich Flögel
Background-free fluorine (19F) MR imaging exhibits an excellent degree of specificity, and facilitates among others the in vivo visualization of inflammatory processes. Merging19F MR images with morphologically matching1H MR images enables the exact anatomic localization of the observed19F signal. Biochemically inert nanoemulsions of perfluorocarbons, which are known to be taken up by the macrophage/monocyte system, are widely used as contrast agents for preclinical applications. Herein, the most common protocols are described to obtain high-resolution and artifact-free19F MR images even for compounds with complex19F MR spectra...
2018: Methods in Molecular Biology
https://www.readbyqxmd.com/read/29329927/systems-biomarkers-in-psoriasis-integrative-evaluation-of-computational-and-experimental-data-at-transcript-and-protein-levels
#2
Tuba Sevimoglu, Beste Turanli, Ceyhun Bereketoglu, Kazim Yalcin Arga, Ayse Serap Karadag
Psoriasis is a complex autoimmune disease with multiple genes and proteins being involved in its pathogenesis. Despite the efforts performed to understand mechanisms of psoriasis pathogenesis and to identify diagnostic and prognostic targets, disease-specific and effective biomarkers were still not available. This study is compiled regarding clinical validation of computationally proposed biomarkers at gene and protein expression levels through qRT-PCR and ELISA techniques using skin biopsies and blood plasma...
January 9, 2018: Gene
https://www.readbyqxmd.com/read/29313270/ultrasound-elastography-based-assessment-of-the-elasticity-of-the-supraspinatus-muscle-in-impingement-syndrome-does-elastography-has-any-diagnostic-value
#3
Adnan Demirel, Murat Baykara, Tuba Tülay Koca, Ejder Berk
Ultrasound elastography (UE) is a new ultrasound-based imaging technique that provides information about elasticity and stiffness of tissues. This cross-sectional study aimed to identify the diagnostic importance of UE in supraspinatus impingement syndrome. Forty-one subjects, aged 38-70 years, were included in the study. UE was used to determine the elasticity of the supraspinatus muscle. The strain ratio was calculated as the evaluation criteria to measure the elasticity of the muscle. High strain ratio indicated low elasticity...
January 8, 2018: Clinical Rheumatology
https://www.readbyqxmd.com/read/29245427/species-of-i-macrostomum-i-macrostomorpha-macrostomidae-from-the-coastal-region-of-lima-peru-with-comments-on-i-m-rostratum-i-papi-1951
#4
Jhoe Reyes, Francisco Brusa
Species of Macrostomum are present in almost all regions of the world. These flatworms occur in different kinds of environments, from freshwater to marine ecosystems. Although Peru is considered one of the megadiverse countries in South America, little is known about freshwater microturbellarians in this country. Here we report the presence of M. rostratum Papi, 1951 for the first time in Peru, in a coastal brackish water wetland, and that of M. quiritium Beklemischev, 1951 and M. tuba Graff, 1882 in an inland portion of a river near the city of Lima...
December 5, 2017: Zootaxa
https://www.readbyqxmd.com/read/29226893/assessment-of-factors-related-to-statin-non-adherence-in-patients-with-established-coronary-artery-disease-a-single-center-observational-study
#5
Tuba Özdemir, İrfan Şahin, İlhan İlker Avcı, Barış Güngör, Eser Durmaz, Sevil Tuğrul, Mert İlker Hayıroğlu, Serdar Kahyaoğlu, Orkhan Karımov, Ertuğrul Okuyan
OBJECTIVE: Lifelong statin treatment is recommended in patients with cardiovascular diseases, but drug adherence is a significant problem. The aim of this study was to investigate factors related to statin discontinuation in high-risk patients with coronary artery disease (CAD) diagnosed by coronary angiography. METHODS: A total of 300 consecutive patients who were followed-up with a diagnosis of CAD were recruited. Patients were categorized as statin adherent or statin non-adherent (patients interrupting statin therapy >30 days)...
December 2017: Türk Kardiyoloji Derneği Arşivi: Türk Kardiyoloji Derneğinin Yayın Organıdır
https://www.readbyqxmd.com/read/29202291/modeling-the-effects-of-climatic-and-land-use-changes-on-phytoplankton-and-water-quality-of-the-largest-turkish-freshwater-lake-lake-bey%C3%A5-ehir
#6
Tuba Bucak, Dennis Trolle, Ü Nihan Tavşanoğlu, A İdil Çakıroğlu, Arda Özen, Erik Jeppesen, Meryem Beklioğlu
Climate change and intense land use practices are the main threats to ecosystem structure and services of Mediterranean lakes. Therefore, it is essential to predict the future changes and develop mitigation measures to combat such pressures. In this study, Lake Beyşehir, the largest freshwater lake in the Mediterranean basin, was selected to study the impacts of climate change and various land use scenarios on the ecosystem dynamics of Mediterranean freshwater ecosystems and the services that they provide...
December 1, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/29194316/tubastatin-a-prevents-hemorrhage-induced-endothelial-barrier-dysfunction
#7
Peter J Bruhn, Vahagn C Nikolian, Ihab Halaweish, Zhigang Chang, Martin Sillesen, Baoling Liu, Yongqing Li, Hasan B Alam
BACKGROUND: Microvascular hyperpermeability resulting from endothelial barrier dysfunction (EBD) is associated with worse clinical outcomes in trauma-induced hemorrhagic shock. We have previously shown that treatment with Tubastatin A (TubA), a histone deacetylase 6 inhibitor, improves outcomes in animal models of shock. In this study, we investigate whether TubA treatment may prevent trauma-related EBD. METHODS: Wistar-Kyoto rats subjected to 40% hemorrhage were treated with TubA or vehicle control...
November 21, 2017: Journal of Trauma and Acute Care Surgery
https://www.readbyqxmd.com/read/29188779/mrsa-prevalence-and-susceptibility-pattern-in-health-care-setups-of-karachi
#8
Tuba Siddiqui, Iyad Naeem Muhammad, Muhammad Naseem Khan, Shazia Naz, Lubna Bashir, Nosheen Sarosh, Rida Masood, Aatka Ali, Sakina Fatima, Talat Naqvi
This assessment aims to determine the prevalence of methicillin resistance and multidrug resistance (MDR) among the clinical isolates of Staphylococcus aureus and antimicrobial susceptibility profile of methicillin resistant Staphylococcus aureus (MRSA) to the frequently prescribed antibiotics in Karachi. Isolates of MRSA, recovered from various clinical samples were included in this prospective, cross-sectional study from Jan 2015 to June 2017. Agar diffusion method was employed according to the protocols of Clinical Laboratory Standards Institute...
November 2017: Pakistan Journal of Pharmaceutical Sciences
https://www.readbyqxmd.com/read/29181317/a-predictive-score-for-retinopathy-of-prematurity-by-using-clinical-risk-factors-and-serum-insulin-like-growth-factor-1-levels
#9
Yeşim Coşkun, Ceyhun Dalkan, Özge Yabaş, Özlem Ünay Demirel, Elif Samiye Bayar, Sibel Sakarya, Tuba Müftüoğlu, Dilaver Erşanlı, Nerin Bahçeciler, İpek Akman
AIM: To detect the impact of insulin-like growth factor-1 (IGF-1) and other risk factors for the early prediction of retinopathy of prematurity (ROP) and to establish a scoring system for ROP prediction by using clinical criteria and serum IGF-1 levels. METHODS: The study was conducted with 127 preterm infants. IGF-1 levels in the 1st day of life, 1st, 2nd, 3rd and 4th week of life was analyzed. The score was established after logistic regression analysis, considering the impact of each variable on the occurrences of any stage ROP...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/29177841/xanthogranulomatous-pyelonephritis-a-case-with-rare-adhesion-to-pancreas
#10
Tuba Devrim, Pınar Atasoy, Devrim Tuğlu
Xanthogranulomatous pyelonephritis (XGP) is a rare benign condition with unknown aetiology and chronic infection of kidney. Commonly, most cases are related with urinary tract obstruction, nephrolithiasis, infection, diabetes, and/or immune compromise. XGP is associated with destruction of the renal parenchyma and granulomatous inflammation with foamy lipid-laden macrophages resulting from obstructive uropathy. It closely mimics a malignancy, exhibiting local tissue invasion and destruction. Adjacent organs especially duodenum as well as very rarely pancreas or spleen may be involved...
November 25, 2017: CEN Case Reports
https://www.readbyqxmd.com/read/29174060/feasibility-of-a-6-month-yoga-program-to-improve-the-physical-and-psychosocial-status-of-persons-with-multiple-sclerosis-and-their-family-members
#11
Turhan Kahraman, Asiye Tuba Ozdogar, Pinar Yigit, Ilknur Hosgel, Zaur Mehdiyev, Ozge Ertekin, Serkan Ozakbas
CONTEXT: To the best of our knowledge, there has been no study on yoga that includes both persons with multiple sclerosis (MS) and their family members. Because yoga has therapeutic effects in both persons with MS and healthy persons, we hypothesized that it would be an effective method to improve not only the physical and psychosocial status but also the time persons with MS and their family members spend together. OBJECTIVE: To examine the feasibility of a 6-month (long-term) yoga program to improve the physical and psychosocial status of persons with MS and their family members...
October 23, 2017: Explore: the Journal of Science and Healing
https://www.readbyqxmd.com/read/29168372/tuba-ovarian-auto-amputation-caused-by-ovarian-teratoma-in-an-adolescent-girl
#12
Ahmet Atıcı, Engin Yılmaz, Ayşe Karaman, Sema Apaydın, Çağatay Evrim Afşarlar
Atıcı A, Yılmaz E, Karaman A, Apaydın S, Afşarlar ÇE. Tuba-ovarian auto-amputation caused by ovarian teratoma in an adolescent girl. Turk J Pediatr 2017; 59: 90-92. Ovarian auto-amputation is an extremely rare condition commonly encountered in the perinatal period. Spontaneous or secondary torsion of the ovary caused by an ovarian lesion may result in infarction and subsequent auto-amputation of the ovary. This paper demonstrates a case that underwent laparoscopic appendectomy with an incidental calcified auto-amputated right ovary...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29168364/aggressive-periodontitis-associated-with-kindler-syndrome-in-a-large-kindler-syndrome-pedigree
#13
Tuba Talo Yıldırım, Filiz Acun Kaya, Mustafa Taşkesen, Serkan Dündar, Alihan Bozoğlan, Gülücağ Giray Tekin, Sedat Akdeniz
Talo-Yıldırım T, Acun-Kaya F, Taşkesen M, Dündar S, Bozoğlan A, Tekin GG, Akdeniz S. Aggressive periodontitis associated with Kindler syndrome in a large Kindler syndrome pedigree. Turk J Pediatr 2017; 59: 56-61. Kindler syndrome (KS) is a rare genetic disorder. The clinical features include aggressive periodontal disease and severe desquamative gingivitis. Five individuals with KS were assessed by oral examination, radiographic analysis and periodontal measurements. All the patients' indexes were recorded prior to periodontal treatment and at the end of the 1th, 3th , 6th, 9th and 12th month respectively...
2017: Turkish Journal of Pediatrics
https://www.readbyqxmd.com/read/29168137/pesticide-residues-in-muscles-of-some-marine-fish-species-and-seaweeds-of-iskenderun-bay-northeastern-mediterranean-turkey
#14
Abdurahman Polat, Sevim Polat, Ayşe Simsek, Tuba Terbiyik Kurt, Gülsün Ozyurt
Pesticide residues in muscles of nine marine fish and four seaweed species of Iskenderun Bay (Northeastern Mediterranean) have been investigated. In sampled fish species, two herbicides, three insecticides, two fungicides, and one synergist were identified and quantified. Metribuzin DADK, propamocarb HCl, and piperonyl butoxide (PBO) were detected in all the muscles of sampled fish species. Metribuzin DADK was the most abundant pesticide residue in fish muscles and the highest metribuzin DADK concentration was found in sardine (311...
November 22, 2017: Environmental Science and Pollution Research International
https://www.readbyqxmd.com/read/29155694/paracentral-acute-middle-maculopathy-in-primary-congenital-glaucoma
#15
Yavuz K Aribas, Zeynep Aktas, Kemal Bayrakceken, Tuba Atalay, Sengul Ozdek
PURPOSE: To report a case of primary congenital glaucoma associated with paracentral acute middle maculopathy. METHODS: A case report. RESULTS: A 14-year-old girl with undiagnosed primary congenital glaucoma was referred for the evaluation of sudden vision loss a week after the initial symptoms. Visual acuity was counting fingers at 2 m in the right eye. Examination of her right eye revealed corneal stromal scar like Haab striae, splinter hemorrhage at the temporal border of the optic disk, perivenular hemorrhage, and fern-like white area at the macula...
November 16, 2017: Retinal Cases & Brief Reports
https://www.readbyqxmd.com/read/29144016/what-is-the-protective-effect-of-metformin-on-rat-ovary-against-ischemia-reperfusion-injury
#16
Cemile Dayangan Sayan, Gokhan Karaca, Zehra Sema Ozkan, Ozlem B Tulmac, Aslı Ceylan Isik, Tuba Devrim, Gülcin Aydin, Ilkin Yeral
AIM: The aim of this study was to investigate the protective effect of metformin on the rat ovary against ischemia-reperfusion injury. METHODS: Thirty-seven female Wistar albino rats were used in the study. The rats were divided into five groups, as follows: sham operation group (group 1); torsion group (group 2); torsion/detorsion + saline group (group 3); torsion/detorsion + low-dose metformin group (group 4); and torsion/detorsion + high-dose metformin group (group 5)...
November 16, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/29133097/biological-and-textural-properties-of-underutilized-exudate-gums-of-jammu-and-kashmir-india
#17
Mudasir Bashir, Tuba Usmani, Sundaramoorthy Haripriya, Tanveer Ahmed
Three different exudate gums were studied for their in-vitro antioxidant activity, functional and textural properties. In-vitro antioxidant activity of the gum exudates was evaluated in terms of DPPH radical scavenging, hydroxyl radical scavenging, reducing power and phenolic content assays. Among the gum exudates, almond gum exhibited maximum DPPḢ inhibition of 35.52±1.125% followed by apricot gum and gum arabic at the concentration of 1mg/mL. Gum arabic had significantly higher reducing power than the other exudate gums...
November 10, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/29127120/primary-and-acquired-resistance-to-immune-checkpoint-inhibitors-in-metastatic-melanoma
#18
Tuba N Gide, James S Wilmott, Richard A Scolyer, Georgina V Long
Immune checkpoint inhibitors have revolutionized the treatment of advanced stage metastatic melanoma patients, as well as patients with many other solid cancers, yielding long lasting responses and improved survival. However, a subset of patients who initially respond to immunotherapy, later relapse and develop therapy resistance (termed acquired resistance), while others do not respond at all (termed primary resistance). Primary and acquired resistance are key clinical barriers to further improving outcomes of patients with metastatic melanoma and the known mechanisms underlying them involve various components of the cancer immune cycle, and interactions between multiple signalling molecules and pathways...
November 10, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/29101995/acr-appropriateness-criteria%C3%A2-tinnitus
#19
Marcus M Kessler, Marwan Moussa, Julie Bykowski, Claudia F E Kirsch, Joseph M Aulino, Kevin L Berger, Asim F Choudhri, Terry D Fife, Isabelle M Germano, A Tuba Kendi, Jeffrey H Kim, Michael D Luttrull, Diego Nunez, Lubdha M Shah, Aseem Sharma, Vilaas S Shetty, Sophia C Symko, Rebecca S Cornelius
Tinnitus is the perception of sound in the absence of an external source. It is a common symptom that can be related to hearing loss and other benign causes. However, tinnitus may be disabling and can be the only symptom in a patient with a central nervous system process disorder. History and physical examination are crucial first steps to determine the need for imaging. CT and MRI are useful in the setting of pulsatile tinnitus to evaluate for an underlying vascular anomaly or abnormality. If there is concomitant asymmetric hearing loss, neurologic deficit, or head trauma, imaging should be guided by those respective ACR Appropriateness Criteria® documents, rather than the presence of tinnitus...
November 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/29079835/circulating-haptoglobin-and-metabolic-syndrome-in-renal-transplant-recipients
#20
Isidor Minović, Michele F Eisenga, Ineke J Riphagen, Else van den Berg, Jenny Kootstra-Ros, Anne-Roos S Frenay, Harry van Goor, Gerald Rimbach, Tuba Esatbeyoglu, Andy P Levy, Carlo Ajm Gaillard, Johanna M Geleijnse, Manfred L Eggersdorfer, Gerjan J Navis, Ido P Kema, Stephan J L Bakker
Haptoglobin (Hp) is an acute phase protein that has recently been linked to components of the metabolic syndrome (MetS). We aimed to evaluate Hp as marker of MetS, and to assess its association with long-term outcome in renal transplant recipients (RTR). We measured plasma Hp in a prospective cohort of 699 stable RTR and 149 healthy controls. Median plasma Hp concentration in RTR was 1.4 [interquartile range (IQR), 1.0-1.8] g/L, which was higher compared to 1.1 [0.9-1.4] g/L in controls (P < 0.001). Hp was independently associated with the MetS (β = 0...
October 27, 2017: Scientific Reports
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