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Cerebrovascular disease

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https://www.readbyqxmd.com/read/29029294/cardiovascular-events-in-anti-neutrophil-cytoplasmic-antibody-associated-vasculitis-a-meta-analysis-of-observational-studies
#1
Eline Houben, Erik L Penne, Alexandre E Voskuyl, Joost W van der Heijden, René H J Otten, Maarten Boers, Tiny Hoekstra
Objectives: Several chronic inflammatory diseases are associated with cardiovascular disease, but the risk in ANCA-associated vasculitis is poorly quantified. The aim of the present study was to review the evidence for an increased cardiovascular risk, including ischaemic heart disease, cerebrovascular accidents and peripheral arterial disease, in patients with ANCA-associated vasculitis. Methods: A comprehensive systematic review was conducted in accordance with guidelines of preferred reporting items for systematic reviews and meta-analyses...
September 18, 2017: Rheumatology
https://www.readbyqxmd.com/read/29029108/relative-risks-of-contributing-factors-to-morbidity-and-mortality-in-adults-with-craniopharyngioma-on-gh-replacement
#2
Kevin C J Yuen, Anders F Mattsson, Pia Burman, Eva-Marie Erfurth, Cecilia Camacho-Hubner, Janet L Fox, Johan Verhelst, Mitchell E Geffner, Roger Abs
Context: Craniopharyngioma (CP) in adults, of either childhood-onset (CO-CP) or adult-onset (AO-CP), is associated with increased morbidity and mortality, but data on the relative risks (RRs) of contributing factors are lacking. Objective: To assess the RRs of factors contributing to morbidity and mortality of adults with CO-CP and AO-CP. Methods: Data on 1,669 CP patients from KIMS (Pfizer International Metabolic Database) were analyzed using univariate and multiple Poisson and Cox regression methods...
September 29, 2017: Journal of Clinical Endocrinology and Metabolism
https://www.readbyqxmd.com/read/29028682/current-and-projected-burden-of-disease-from-high-ambient-temperature-in-korea
#3
Soo Eun Chung, Hae-Kwan Cheong, Jae-Hyun Park, Jong-Hun Kim, Hyunjin Han
BACKGROUND: The objective of the present study was to estimate the current and projected burden of disease from high ambient temperature using population-based data sources of nationwide mortality and morbidity in Korea. METHODS: Disability-adjusted life years (DALY) were estimated using noninjury-related deaths, and cerebrovascular and cardiovascular diseases from recently released nationwide health and mortality databases. Years of life lost and years lost due to disability were measured based on the point prevalence and number of deaths during the study period...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/29028677/are-people-with-a-history-of-disease-more-susceptible-to-a-short-term-exposure-to-asian-dust-a-case-crossover-study-among-the-elderly-in-japan
#4
Saori Kashima, Takashi Yorifuji, Etsuji Suzuki
BACKGROUND: Factors influencing the susceptibility of the elderly to the adverse health effects of short-term exposure to desert dust have yet to be explored. We aimed to identify the disease histories that increase the susceptibility of the elderly to disease onset induced by dust events. METHODS: We used a time-stratified case-crossover design using data on 17,874 elderly residents (≥65 years) of Okayama, Japan, who were transported to hospital emergency rooms because of cardiovascular and respiratory diseases between 2006 and 2010...
October 2017: Epidemiology
https://www.readbyqxmd.com/read/29026617/cerebral-vasculitis-and-intracranial-multiple-aneurysms-in-a-child-with-lyme-neuroborreliosis
#5
Elisa Kortela, Jukka Hytönen, Jussi Numminen, Margit Overmyer, Harri Saxen, Jarmo Oksi
Introduction. Lyme borreliosis is a multisystem tick-borne disease caused by Borrelia burgdorferi. Neurological manifestations are reported in up to 15 % of adult patients with Lyme disease, while the frequency among children is higher. The most common manifestations are painful radiculopathy, facial nerve paresis and lymphocytic meningitis. Epileptic seizures and cerebral vasculitis with stroke or aneurysms are very rare complications. Case presentation. We describe a paediatric patient with sensorineural auditory dysfunction, headache, fatigue and epileptic seizures as sequelae of meningoencephalitis/Lyme neuroborreliosis (LNB) caused by B...
April 2017: JMM Case Reports
https://www.readbyqxmd.com/read/29026425/effect-of-cytochrome-p450-2c19-17-allelic-variant-on-cardiovascular-and-cerebrovascular-outcomes-in-clopidogrel-treated-patients-a-systematic-review-and-meta-analysis
#6
REVIEW
Bo Huang, De-Jun Cui, Ying Ren, Bin Han, Da-Ping Yang, Xun Zhao
BACKGROUND: We aimed to evaluate the associations of gain-of-function allele of CYP2C19*17 and risk of clinical events in clopidogrel-treated patients with cardiovascular and cerebrovascular diseases (CCVDs). MATERIALS AND METHODS: Literature search was conducted in PubMed, EMBASE, and Cochrane Library. Odds ratio (OR) combined with 95% confidence interval (CI) was the pooled statistics. Subgroup analysis was performed by disease type, bleeding events, and race...
2017: Journal of Research in Medical Sciences: the Official Journal of Isfahan University of Medical Sciences
https://www.readbyqxmd.com/read/29026289/can-we-predict-postoperative-complications-in-elderly-chinese-patients-with-hip-fractures-using-the-surgical-risk-calculator
#7
Xiao Wang, Bin Jiang Zhao, Yue Su
PURPOSE: Hip fractures are associated with poor prognosis in elderly patients partly due to the high rate of postoperative complications. This study was aimed to investigate whether the surgical risk calculator is suitable for predicting postoperative complications in elderly Chinese patients with hip fractures. METHODS: The incidence of postoperative complications among 410 elderly patients with hip fractures was predicted by the surgical risk calculator and then compared with the actual value...
2017: Clinical Interventions in Aging
https://www.readbyqxmd.com/read/29025684/ninety-day-readmission-and-long-term-mortality-in-medicare-patients-%C3%A2-65-years-treated-with-ticagrelor-versus-prasugrel-after-percutaneous-coronary-intervention-from-the-blue-cross-blue-shield-of-michigan-cardiovascular-consortium
#8
Chris Song, Devraj Sukul, Milan Seth, James M Dupree, Akshay Khandelwal, Simon R Dixon, David Wohns, Thomas LaLonde, Hitinder S Gurm
Ticagrelor and prasugrel were found to be superior to clopidogrel for the treatment of acute coronary syndrome (ACS) after percutaneous coronary intervention (PCI); however, the comparative effectiveness of these 2 drugs remains unknown. We compared postdischarge outcomes among older patients treated with ticagrelor versus prasugrel after PCI for ACS. We linked clinical data from PCIs performed in older patients (age ≥65) for ACS at 47 Michigan hospitals to Medicare fee-for-service claims from January 1, 2013, to December 31, 2014, to ascertain rates of 90-day readmission and long-term mortality...
August 30, 2017: American Journal of Cardiology
https://www.readbyqxmd.com/read/29025039/rehabilitative-post-acute-care-for-stroke-patients-delivered-by-per-diem-payment-system-in-different-hospitalization-paths-a-taiwan-pilot-study
#9
Chung-Yuan Wang, Yu-Ren Chen, Jia-Pei Hong, Chih-Chun Chan, Long-Chung Chang, Hon-Yi Shi
Objective: To explore how post-acute care (PAC) for stroke patients delivered by per-diem payment system in varying hospitalization paths affects medical care utilization and functional status. Design, setting and patients: A longitudinal prospective cohort study of 181 acute stroke patients in a southern Taiwan hospital and patients were separated into two groups: patients transferred from regional hospitals (group 1) and patients referred from medical centers (group 2)...
August 14, 2017: International Journal for Quality in Health Care
https://www.readbyqxmd.com/read/29021415/cerebrovascular-cardiovascular-diseases-and-mental-disorders-due-to-overwork-and-work-related-stress-among-local-public-employees-in-japan
#10
Takashi Yamauchi, Toru Yoshikawa, Takeshi Sasaki, Shun Matsumoto, Masaya Takahashi, Machi Suka, Hiroyuki Yanagisawa
In Japan, overwork-related disorders occur among local public employees as well as those in private businesses. However, to date, there are no studies reporting the state of compensation for cerebrovascular/cardiovascular diseases (CCVD) and mental disorders due to overwork or work-related stress among local public employees in Japan over multiple years. This report examined the recent trend of overwork-related CCVD and mental disorders, including the incidence rates of these disorders, among local public employees in Japan from the perspective of compensation for public accidents, using data from the Japanese Government and relevant organizations...
October 11, 2017: Industrial Health
https://www.readbyqxmd.com/read/29021314/augmented-3d-venous-navigation-for-neuroendovascular-procedures
#11
Raphaël Blanc, Robert Fahed, Pascal Roux, Stanislas Smajda, Gabriele Ciccio, Jean-Philippe Desilles, Hocine Redjem, Mikael Mazighi, Humain Baharvahdat, Michel Piotin
BACKGROUND: Endovascular venous access is increasingly used for the treatment of many cerebrovascular diseases. The quality of venous roadmapping through arterial injection can be problematic because of contrast media dilution, slow flow velocity, and unilateral opacification of the venous system. OBJECTIVE: To describe our experience with the VesselNavigator (Philips Healthcare, Best, The Netherlands) in performing live 3D roadmapping for intracranial venous procedures...
October 11, 2017: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29020367/clinical-outcomes-of-state-of-the-art-percutaneous-coronary-revascularization-in-patients-with-de-novo-three-vessel-disease-1-year-results-of-the-syntax-ii-study
#12
Javier Escaned, Carlos Collet, Nicola Ryan, Giovanni Luigi De Maria, Simon Walsh, Manel Sabate, Justin Davies, Maciej Lesiak, Raul Moreno, Ignacio Cruz-Gonzalez, Stephan P Hoole, Nick Ej West, J J Piek, Azfar Zaman, Farzin Fath-Ordoubadi, Rodney H Stables, Clare Appleby, Nicolas van Mieghem, Robert Jm van Geuns, Neal Uren, Javier Zueco, Pawel Buszman, Andres Iñiguez, Javier Goicolea, David Hildick-Smith, Andrzej Ochala, Dariusz Dudek, Colm Hanratty, Rafael Cavalcante, Arie Pieter Kappetein, David P Taggart, Gerrit-Anne van Es, Marie-Angèle Morel, Ton de Vries, Yoshinobu Onuma, Vasim Farooq, Patrick W Serruys, Adrian P Banning
Aims: To investigate if recent technical and procedural developments in percutaneous coronary intervention (PCI) significantly influence outcomes in appropriately selected patients with three-vessel (3VD) coronary artery disease. Methods and results: The SYNTAX II study is a multicenter, all-comers, open-label, single arm study that investigated the impact of a contemporary PCI strategy on clinical outcomes in patients with 3VD in 22 centres from four European countries...
August 26, 2017: European Heart Journal
https://www.readbyqxmd.com/read/29020302/cerebrovascular-diseases-in-poland-inconsistent-seasonal-patterns-of-hospitalisation-and-mortality
#13
Anna Poznanska, Bogdan Wojtyniak, Kamil Chwojnicki, Katarzyna Lewtak, Barbara Rubikowska, Wojciech Seroka
Background: A seasonal variation in the incidence of cerebrovascular diseases still remains inconsistently evidenced. Herein, we analyse the monthly patterns of two health phenomena: hospital admissions and deaths due to these diseases. Methods: We identified 69 511 cases of hospital admissions and 14 956 deaths due to cerebrovascular diseases (ICD10: I60-I69 and G45) among the inhabitants of five Polish voivodeship capitals in 2004-13. The method of time series analysis (exponential smoothing with linear trend and monthly additive seasonality) was applied to calculate the monthly specific seasonal indices...
September 13, 2017: European Journal of Public Health
https://www.readbyqxmd.com/read/29019879/percutaneous-coronary-intervention-versus-cardiac-bypass-surgery-for-left-main-coronary-artery-disease-a-trial-sequential-analysis
#14
Yicong Ye, Ming Yang, Shuyang Zhang, Yong Zeng
BACKGROUND: Several updated meta-analyses comparing percutaneous coronary intervention (PCI) with coronary artery bypass grafting (CABG) for left main coronary artery disease (LM CAD) have been published recently. However, the risk of false-positive results could be high in conventional updated meta-analyses due to repetitive testing of accumulating data. Therefore, we compared these treatment approaches via trial sequential analysis (TSA). METHODS: The MEDLINE, Embase, and Cochrane Central Register of Controlled Trials databases were searched for published randomized controlled trials (RCTs) or subgroups of RCTs comparing PCI and CABG in patients with LM CAD...
October 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29019809/atrial-fibrillation-and-central-nervous-complications-in-liver-transplanted-hereditary-transthyretin-amyloidosis-patients
#15
Niklas Wange, Intissar Anan, Bo-Göran Ericzon, Johanna Pennlert, Björn Pilebro, Ole B Suhr, Jonas Wixner
BACKGROUND: Central nervous system (CNS) complications are increasingly noted in liver transplanted (LTx) hereditary transthyretin amyloid (ATTRm) amyloidosis patients; this suggests that the increased survival allows for intracranial ATTRm formation from brain synthesised mutant TTR. However, atrial fibrillation (AF), a recognised risk factor for ischemic CNS complications, is also observed after LTx. The aim of the study was to investigate the occurrence of CNS complications and AF in LTx ATTRm amyloidosis patients...
October 11, 2017: Transplantation
https://www.readbyqxmd.com/read/29018934/quantitative-susceptibility-mapping-of-the-motor-cortex-a-comparison-of-susceptibility-among-patients-with-amyotrophic-lateral-sclerosis-cerebrovascular-disease-and-healthy-controls
#16
Ji Young Lee, Young-Jun Lee, Dong Woo Park, Yoonho Nam, Seung Hyun Kim, Jinseok Park, Young Seo Kim, Hyun Young Kim, Ki-Wook Oh
PURPOSE: The purpose of this study was to investigate the differences in motor cortex susceptibility among patients with amyotrophic lateral sclerosis (ALS), cerebrovascular disease (CVD), and healthy controls using quantitative susceptibility mapping (QSM). METHODS: We retrospectively reviewed 78 QSM images from 26 patients with ALS, 26 age- and sex-matched patients with CVD, and 26 healthy controls. A region of interest was drawn in the hand lobule of both the motor cortexes and subcortical white matter...
October 11, 2017: Neuroradiology
https://www.readbyqxmd.com/read/29018399/therapeutic-interventions-for-vascular-parkinsonism-a-systematic-review-and-meta-analysis
#17
Adán Miguel-Puga, Gabriel Villafuerte, José Salas-Pacheco, Oscar Arias-Carrión
BACKGROUND: Vascular parkinsonism (VP) is defined as the presence of parkinsonian syndrome, evidence of cerebrovascular disease, and an established relationship between the two disorders. However, the diagnosis of VP is problematic, particularly for the clinician confronted with moving from diagnosis to treatment. Given the different criteria used in the diagnosis of VP, the effectiveness of available therapeutic interventions for this disease are currently unknown. METHODS: To assess the clinical response of all published therapeutic interventions for VP that have been reported in the literature, we conducted a systematic review looking for VP subjects treated with any therapeutic intervention...
2017: Frontiers in Neurology
https://www.readbyqxmd.com/read/29017805/atherosclerotic-plaque-characteristics-are-not-associated-with-future-cardiovascular-events-in-patients-undergoing-iliofemoral-endarterectomy
#18
Steven T W van Haelst, Saskia Haitjema, Wouter Derksen, Ian van Koeverden, Jean-Paul P M de Vries, Frans L Moll, Hester M den Ruijter, Gerard Pasterkamp, Gert J de Borst
BACKGROUND: Plaque characteristics such as intraplaque hemorrhage (IPH) have been associated with secondary cardiovascular events (CVE) in patients undergoing carotid endarterectomy. In addition, carotid plaques containing macrophage infiltration or a large lipid core size were associated with less restenosis. It is currently unknown whether iliofemoral plaque histopathologic characteristics are predictive for secondary CVE in patients with peripheral arterial disease undergoing iliofemoral endarterectomy...
October 7, 2017: Journal of Vascular Surgery
https://www.readbyqxmd.com/read/29017533/persistent-organic-pollutants-and-mortality-in-the-united-states-nhanes-1999-2011
#19
Kristiann Fry, Melinda C Power
BACKGROUND: Persistent organic pollutants (POPs) are environmentally and biologically persistent chemicals that include polybrominated diphenyl ethers (PBDEs), per- and polyfluoroalkyl substances (PFASs), polychlorinated biphenyls (PCBs), and organochlorine (OC) pesticides. Currently, data on the associations between exposure to POPs and the risk of mortality in the U.S. population is limited. Our objective was to determine if higher exposure to POPs is associated with greater risk of all-cause, cancer, heart/cerebrovascular disease, or other-cause mortality...
October 10, 2017: Environmental Health: a Global Access Science Source
https://www.readbyqxmd.com/read/28994390/clearance-of-beta-amyloid-is-facilitated-by-apolipoprotein-e-and-circulating-high-density-lipoproteins-in-bioengineered-human-vessels
#20
Jerome Robert, Emily B Button, Brian Yuen, Megan Gilmour, Kevin Kang, Arvin Bahrabadi, Sophie Stukas, Wenchen Zhao, Iva Kulic, Cheryl L Wellington
Amyloid plaques, consisting of deposited beta-amyloid (Aβ), are a neuropathological hallmark of Alzheimer's Disease (AD). Cerebral vessels play a major role in AD, as Aβ is cleared from the brain by pathways involving the cerebrovasculature, most AD patients have cerebrovascular amyloid (cerebral amyloid angiopathy (CAA), and cardiovascular risk factors increase dementia risk. Here we present a notable advance in vascular tissue engineering by generating the first functional 3-dimensioinal model of CAA in bioengineered human vessels...
October 10, 2017: ELife
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