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https://www.readbyqxmd.com/read/27907839/influence-of-picolinic-acid-on-seizure-susceptibility-in-mice
#1
Anna Cioczek-Czuczwar, Piotr Czuczwar, Waldemar Andrzej Turski, Jolanta Parada-Turska
BACKGROUND: The mechanism of drug resistance in epilepsy remains unknown. Picolinic acid (PIC) is an endogenous metabolite of the kynurenine pathway and a chelating agent added to dietary supplements. Both inhibitory and excitatory properties of PIC were reported. The aim of this study was to determine the influence of exogenously applied PIC upon the electroconvulsive threshold and the activity of chemical convulsants in eight models of epilepsy in mice. METHODS: All experiments were performed on adult male Swiss albino mice...
October 12, 2016: Pharmacological Reports: PR
https://www.readbyqxmd.com/read/27906375/surface-modulation-and-back-reflection-from-foil-targets-irradiated-by-a-petawatt-femtosecond-laser-pulse-at-oblique-incidence
#2
S Ter-Avetisyan, A Andreev, K Platonov, J H Sung, S K Lee, H W Lee, J Y Yoo, P K Singh, H Ahmed, C Scullion, K F Kakolee, T W Jeong, P Hadjisolomou, M Borghesi
A significant level of back reflected laser energy was measured during the interaction of ultra-short, high contrast PW laser pulses with solid targets at 30° incidence. 2D PIC simulations carried out for the experimental conditions show that at the laser-target interface a dynamic regular structure is generated during the interaction, which acts as a grating (quasi-grating) and reflects back a significant amount of incident laser energy. With increasing laser intensity above 10<sup>18</sup> W/cm<sup>2</sup> the back reflected fraction increases due to the growth of the surface modulation to larger amplitudes...
November 28, 2016: Optics Express
https://www.readbyqxmd.com/read/27905389/-lipid-profile-and-psychometric-traits-in-patients-with-psychosomatic-disorders-and-chronic-cerebral-ischemia
#3
A V Shevchenko, B M Doronin, V B Kuznetsova, T G Amstislavskaya
AIM: To explore the correlation of serum cholesterol and triglycerides with psychometric traits in patients with psychosomatic disorders and chronic cerebral ischemia (CCI). MATERIAL AND METHODS: One hundred and ten patients with CCI, aged from 46 to 76 years, were examined. Total cholesterol and triglycerides were measured in the blood. A battery of tests for assessment of cognitive functions and neurotic traits was used. RESULTS: The level of cholesterol was higher in patients with post-infarction cardiosclerosis (PICS) compared to patients with CCI without psychosomatic disorders but did not differ from that in patients with gastric ulcer (GU)...
2016: Zhurnal Nevrologii i Psikhiatrii Imeni S.S. Korsakova
https://www.readbyqxmd.com/read/27899137/ethnobotanical-survey-of-cosmetic-plants-used-in-marquesas-islands-french-polynesia
#4
Xénia Jost, Jean-Luc Ansel, Gaël Lecellier, Phila Raharivelomanana, Jean-François Butaud
BACKGROUND: Cosmetic plants and their uses have often been neglected in ethnobotanical surveys which focus mainly on plants with medicinal or food uses. Thus, this survey was carried out to specifically investigate cosmetics in a small community and to establish a cosmetopoeia, based on the model of pharmacopoeia for medicinal plants. The geographic spread of the survey covered the Marquesas Islands, one of the five archipelagos of French Polynesia (Pacific Ocean). This archipelago was also recently investigated for its pharmacopoeia...
November 29, 2016: Journal of Ethnobiology and Ethnomedicine
https://www.readbyqxmd.com/read/27898971/evaluating-the-impact-of-maternal-vitamin-d-supplementation-on-sow-performance-ii-subsequent-growth-performance-and-carcass-characteristics-of-growing-pigs
#5
J R Flohr, J C Woodworth, J R Bergstrom, M D Tokach, S S Dritz, R D Goodband, J M DeRouchey
A of subsample of 448 growing pigs (PIC 327 × 1050) weaned from 52 sows fed varying dietary vitamin D regimens were used in a split-plot design to determine the effects of maternal and nursery dietary vitamin D on growth performance. Sows were previously administered diets containing vitamin D as vitamin D (800, 2,000, or 9,600 IU/kg) or as 25(OH)D (50 µg [or 2,000 IU vitamin D equivalent]/kg from HyD; DSM Nutritional Products, Parsippany, NJ). Once weaned, pigs were allotted to pens on the basis of previous maternal vitamin D treatment, and then pens were randomly assigned to 1 of 2 nursery vitamin D dietary regimens (2,000 IU of vitamin D/kg or 50 µg 25(OH)D/kg)...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898964/evaluating-the-impact-of-maternal-vitamin-d-supplementation-i-sow-performance-serum-vitamin-metabolites-and-neonatal-muscle-characteristics
#6
J R Flohr, J C Woodworth, J R Bergstrom, M D Tokach, S S Dritz, R D Goodband, J M DeRouchey
In Exp. 1, 56 gestating sows (PIC 1050; 35 d postinsemination) were used in a 30-d trial to determine serum 25(OH)D response to increasing concentrations of dietary vitamin D. Sows were randomly allotted to 1 of 7 dietary D treatments (200, 800, 1,600, 3,200, 6,400, 12,800, or 25,600 IU of added D per kilogram of complete diet) with 8 sows per treatment. Increasing D increased (quadratic; < 0.001) serum 25(OH)D with the response depicted by the prediction equation: serum 25(OH)D, ng/mL = 35.1746 + (0.002353 × dietary D, IU/d) - (0...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898939/evaluating-pellet-and-meal-feeding-regimens-on-finishing-pig-performance-stomach-morphology-and-carcass-characteristics
#7
J A De Jong, J M DeRouchey, M D Tokach, S S Dritz, R D Goodband, J C Woodworth, M W Allerson
A total of 2,100 pigs (PIC 327 × 1050; initially 31.2 kg BW) were used in a 118-d trial to determine the effects of pellet or meal feeding regimens on finishing pig growth performance, stomach morphology, and carcass characteristics. Pens of pigs were balanced by initial BW and randomly allotted to 1 of 6 dietary treatments (14 pens/treatment with 25 pigs/pen). Pens were sorted by gender allowing for 7 barrow pens and 7 gilt pens per treatment. The same corn-soybean meal-based diets containing 15% dried distillers' grains with solubles were used for all treatments and fed in 5 phases...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27898929/does-heat-stress-alter-the-pig-s-response-to-dietary-fat
#8
T A Kellner, L H Baumgard, K J Prusa, N K Gabler, J F Patience
Heat stress (HS) results in major losses to the pork industry via reduced growth performance and, possibly, carcass fat quality. The experimental objective was to measure the effects of HS on the pig's response to dietary fat in terms of lipid digestion, metabolism, and deposition over a 35-d finishing period. A total of 96 PIC 337 × C22/C29 (PIC, Inc., Hendersonville, TN) barrows (initial BW of 100.4 ± 1.2 kg) were randomly allotted to 1 of 9 treatments arranged as a 3 × 3 factorial: thermoneutral (TN; constant 24°C; ad libitum access to feed), pair-fed thermoneutral (PFTN; constant 24°C; limit fed based on previous HS daily feed intake), or HS (cyclical 28°C nighttime, 33°C from d 0 to 7, 33...
November 2016: Journal of Animal Science
https://www.readbyqxmd.com/read/27893232/narrative-production-in-children-with-autism-spectrum-disorder-asd-and-children-with-attention-deficit-hyperactivity-disorder-adhd-similarities-and-differences
#9
Sanne J M Kuijper, Catharina A Hartman, Suzanne T M Bogaerds-Hazenberg, Petra Hendriks
The present study focuses on the similarities and differences in language production between children with autism spectrum disorder (ASD) and children with attention-deficit/hyperactivity disorder (ADHD). In addition, we investigated whether Theory of Mind (ToM), working memory, and response inhibition are associated with language production. Narratives, produced by 106 Dutch-speaking children (36 with ASD, 34 with ADHD, and 36 typically developing) aged 6 to 12 during ADOS assessment, were examined on several linguistic measures: verbal productivity, speech fluency, syntactic complexity, lexical semantics, and discourse pragmatics...
November 28, 2016: Journal of Abnormal Psychology
https://www.readbyqxmd.com/read/27891245/genetic-diversity-of-halla-horses-using-microsatellite-markers
#10
Joo-Hee Seo, Kyung-Do Park, Hak-Kyo Lee, Hong-Sik Kong
BACKGROUND: Currently about 26,000 horses are breeding in Korea and 57.2% (14,776 horses) of them are breeding in Jeju island. According to the statistics published in 2010, the horses breeding in Jeju island are subdivided into Jeju horse (6.1%), Thoroughbred (18.8%) and Halla horse (75.1%). Halla horses are defined as a crossbreed between Jeju and Thoroughbred horses and are used for horse racing, horse riding and horse meat production. However, little research has been conducted on Halla horses because of the perception of crossbreed and people's weighted interest toward Jeju horses...
2016: Journal of Animal Science and Technology
https://www.readbyqxmd.com/read/27890101/genetic-polymorphism-studies-on-22-autosomal-str-loci-of-the-powerplex-fusion-system-in-bangladeshi-population
#11
Tania Hossain, Mahamud Hasan, Ashish K Mazumder, Pilu Momtaz, Abu Sufian, Jabedul Alam Khandaker, Sharif Akhteruzzaman
Genetic polymorphism of 22 autosomal STR loci included in PowerPlex® Fusion System (D3S1358, D1S1656, D2S441, D10S1248, D13S317, Penta E, D16S539, D18S51, D2S1338, CSF1PO, Penta D, TH01, vWA, D21S11, D7S820, D5S818, TPOX, D8S1179, D12S391, D19S433, FGA and D22S1045) was studied in 188 unrelated Bangladeshi Bengali individuals. Allele frequencies and forensic efficiency parameters such as, the power of discrimination (PD), observed and expected heterozygosity (Ho & He), polymorphism information content (PIC), probability of match (PM), power of exclusion (PE) and typical paternity index was calculated for the loci...
November 2016: Legal Medicine
https://www.readbyqxmd.com/read/27883344/analysis-of-non-eeg-evidence-for-preparatory-activity-in-the-human-brain-pre-contraction-impedance-changes-in-skeletal-muscles
#12
Carl Shiffman
Precontraction impedance changes (PICs) are known to occur during isometric contractions of the human forearm finger flexors. Without reliance on electroencephalogical data these are construed as evidence for the construction of a 'template of instructions' in the brain for muscle contractions to be performed once a 'go' instruction is received, as widely expected from EEG measurements A model is proposed to explain earlier impedance results, based on a PIC-associated time-dependent inhibitory constraint and a modified role for the 'go' command...
November 24, 2016: Physiological Measurement
https://www.readbyqxmd.com/read/27878351/c-reactive-protein-indicates-early-stage-of-postoperative-infectious-complications-in-patients-following-minimally-invasive-esophagectomy
#13
Yuichiro Miki, Takahiro Toyokawa, Naoshi Kubo, Tatsuro Tamura, Katsunobu Sakurai, Hiroaki Tanaka, Kazuya Muguruma, Masakazu Yashiro, Kosei Hirakawa, Masaichi Ohira
BACKGROUND: Esophagectomy for patients with esophageal cancer is associated with high rate of postoperative infectious complications (PICs). Although minimally invasive esophagectomy (MIE) could reduce the rate of PICs, its incidence cannot be ignored. Early detection of PICs may be beneficial in clinical settings. We investigated whether systemic inflammation markers, such as C-reactive protein (CRP) and white blood cell count (WBC), are useful for the early detection of PICs. METHOD: We reviewed 158 patients who underwent MIE from 2000 to 2015 and assessed PIC incidence and severity...
November 22, 2016: World Journal of Surgery
https://www.readbyqxmd.com/read/27875283/does-persistent-inflammatory-catabolic-syndrome-exist-in-critically-ill-neonates
#14
Nicole Ellis, Caitlin Hughes, Vera Mazurak, Chloe Joynt, Bodil Larsen
BACKGROUND: Persistent inflammatory catabolic syndrome (PICS) has not been described in the infant population. This study proposes a definition of PICS in critically ill infants. METHODS: A published adult criterion of PICS was modified using anthropometric and biochemical reference ranges for infants. A prospective chart review of admissions to a tertiary surgical neonatal intensive care unit (NICU) was performed over 65 days. Demographic, anthropometric, biochemical, and other clinical variables such as length of stay and medication use were collected daily throughout admission...
October 10, 2016: JPEN. Journal of Parenteral and Enteral Nutrition
https://www.readbyqxmd.com/read/27859709/dietary-chicory-root-and-chicory-inulin-trigger-changes-in-energetic-metabolism-stress-prevention-and-cytoskeletal-proteins-in-the-liver-of-growing-pigs-a-proteomic-study
#15
A Lepczyński, A Herosimczyk, M Ożgo, M Marynowska, M Pawlikowska, M Barszcz, M Taciak, J Skomiał
Currently, a wide array of plant preparations exerting health-promoting properties are commonly used as feed additives. Among them, Cichorium intybus L. have gained considerable attention as a source of compounds showing prebiotic character. Large body of evidence suggests that products of prebiotic fermentation (short-chain fatty acids) may influence the expression of genes encoding liver enzymes involved in the regulation of energetic metabolism. Given the above, the present study was aimed at estimating the influence of a diet supplemented with chicory root or water extract of chicory inulin on liver proteome in growing pigs...
November 17, 2016: Journal of Animal Physiology and Animal Nutrition
https://www.readbyqxmd.com/read/27858515/eif4b-stimulates-eif4a-atpase-and-unwinding-activities-by-direct-interaction-through-its-7-repeats-region
#16
Alexandra Zoi Andreou, Ulf Harms, Dagmar Klostermeier
Eukaryotic translation initiation starts with binding of the eIF4F complex to the 5'-m7G cap of the mRNA. Recruitment of the 43S pre-initiation complex (PIC), formed by the 40S ribosomal subunit and other translation initiation factors, leads to formation of the 48S PIC that then scans the 5'-untranslated region (5'-UTR) towards the start codon. The eIF4F complex consists of eIF4E, the cap binding protein, eIF4A, a DEAD-box RNA helicase that is believed to unwind secondary structures in the 5'UTR during scanning, and eIF4G, a scaffold protein that binds to both eIF4E and eIF4A...
November 18, 2016: RNA Biology
https://www.readbyqxmd.com/read/27853776/catalyst-solvent-interactions-in-a-dinuclear-ru-based-water-oxidation-catalyst
#17
Andrey Shatskiy, Reiner Lomoth, Ahmed F Abdel-Magied, Wangchuk Rabten, Tanja M Laine, Hong Chen, Junliang Sun, Pher G Andersson, Markus D Kärkäs, Eric V Johnston, Björn Åkermark
Photocatalytic water oxidation represents a key process in conversion of solar energy into fuels and can be facilitated by the use of molecular transition metal-based catalysts. A novel straightforward approach for covalent linking of the catalytic units to other moieties is demonstrated by preparation of a dinuclear complex containing two [Ru(pdc)(pic)3]-derived units (pdc = 2,6-pyridinedicarboxylate, pic = 4-picoline). The activity of this complex towards chemical and photochemical oxidation of water was evaluated and a detailed insight is given into the interactions between the catalyst and acetonitrile, a common co-solvent employed to increase solubility of water oxidation catalysts...
November 17, 2016: Dalton Transactions: An International Journal of Inorganic Chemistry
https://www.readbyqxmd.com/read/27848000/effects-of-post-fire-plant-cover-in-the-performance-of-two-cordilleran-cypress-austrocedrus-chilensis-seedling-stocktypes-planted-in-burned-forests-of-northeastern-patagonia-argentina
#18
María F Urretavizcaya, Héctor E Gonda, Guillermo E Defossé
Cordilleran cypress (Austrocedrus chilensis [D.Don] Pic. Serm. et Bizarri) forests occupy 140,000 ha along a sharp environmental gradient of central Andean-Patagonia in Argentina. Every summer, about 3200 ha of these forests are affected by wildfires, taking thereafter long time to recover. To accelerate forest recovery, we determined in xeric and mesic cypress stands burned 5 and 2 year before whether survival and growth of two planted cypress seedling stocktypes are affected by plant cover and contrasting precipitation conditions...
November 15, 2016: Environmental Management
https://www.readbyqxmd.com/read/27843406/theory-of-electric-creep-and-electromechanical-coupling-with-domain-evolution-for-non-poled-and-fully-poled-ferroelectric-ceramics
#19
Xiaodong Xia, Yang Wang, Zheng Zhong, George J Weng
Unlike mechanical creep with inelastic deformation, electric creep with domain evolution is a rarely studied subject. In this paper, we present a theory of electric creep and related electromechanical coupling for both non-poled and fully poled ferroelectric ceramics. We consider electric creep to be a time-dependent process, with an initial condition lying on the D (electric displacement) versus E (electric field) hysteresis loop. Both processes are shown to share the same Gibbs free energy and thermodynamic driving force, but relative to creep, the hysteresis loop is just a field-dependent process...
October 2016: Proceedings. Mathematical, Physical, and Engineering Sciences
https://www.readbyqxmd.com/read/27836791/pharmacological-inhibition-of-pten-attenuates-cognitive-deficits-caused-by-neonatal-repeated-exposures-to-isoflurane-via-inhibition-of-nr2b-mediated-tau-phosphorylation-in-rats
#20
Lei Tan, Xin Chen, Wei Wang, Jianfang Zhang, Shiyong Li, Yilin Zhao, Jintao Wang, Ailin Luo
Evidence has shown that children exposed to repeated anesthesia in early childhood display long-term cognitive disabilities. However, the underlying mechanisms remain largely unclear. Our previous study has indicated the involvement of phosphatase and tensin homolog deleted on chromosome 10 (PTEN) in isoflurane-induced decrease of self-renewal capacity in hippocampal neural precursor cells. Additionally, it is demonstrated by others that PTEN inhibition could protect against cognitive impairment via reduction of tau phosphorylation in the alzheimer's disease model...
November 8, 2016: Neuropharmacology
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