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https://www.readbyqxmd.com/read/28719597/pharmacogenomics-study-of-thiazide-diuretics-and-qt-interval-in-multi-ethnic-populations-the-cohorts-for-heart-and-aging-research-in-genomic-epidemiology
#1
A A Seyerle, C M Sitlani, R Noordam, S M Gogarten, J Li, X Li, D S Evans, F Sun, M A Laaksonen, A Isaacs, K Kristiansson, H M Highland, J D Stewart, T B Harris, S Trompet, J C Bis, G M Peloso, J A Brody, L Broer, E L Busch, Q Duan, A M Stilp, C J O'Donnell, P W Macfarlane, J S Floyd, J A Kors, H J Lin, R Li-Gao, T Sofer, R Méndez-Giráldez, S R Cummings, S R Heckbert, A Hofman, I Ford, Y Li, L J Launer, K Porthan, C Newton-Cheh, M D Napier, K F Kerr, A P Reiner, K M Rice, J Roach, B M Buckley, E Z Soliman, R de Mutsert, N Sotoodehnia, A G Uitterlinden, K E North, C R Lee, V Gudnason, T Stürmer, F R Rosendaal, K D Taylor, K L Wiggins, J G Wilson, Y-DI Chen, R C Kaplan, K Wilhelmsen, L A Cupples, V Salomaa, C van Duijn, J W Jukema, Y Liu, D O Mook-Kanamori, L A Lange, R S Vasan, A V Smith, B H Stricker, C C Laurie, J I Rotter, E A Whitsel, B M Psaty, C L Avery
Thiazide diuretics, commonly used antihypertensives, may cause QT interval (QT) prolongation, a risk factor for highly fatal and difficult to predict ventricular arrhythmias. We examined whether common single-nucleotide polymorphisms (SNPs) modified the association between thiazide use and QT or its component parts (QRS interval, JT interval) by performing ancestry-specific, trans-ethnic and cross-phenotype genome-wide analyses of European (66%), African American (15%) and Hispanic (19%) populations (N=78 199), leveraging longitudinal data, incorporating corrected standard errors to account for underestimation of interaction estimate variances and evaluating evidence for pathway enrichment...
July 18, 2017: Pharmacogenomics Journal
https://www.readbyqxmd.com/read/28626081/why-publish-in-the-american-journal-of-physiology-heart-and-circulatory-physiology
#2
Irving H Zucker, Merry L Lindsey, Mario Delmar, Leon J De Windt, Christine Des Rosiers, Debra I Diz, Robert L Hester, Steven P Jones, Nancy L Kanagy, Masafumi Kitakaze, Ronglih Liao, Gary D Lopaschuk, Kaushik P Patel, Fabio A Recchia, Junichi Sadoshima, Ajay M Shah, Zoltan I Ungvari, Ivor J Benjamin, Mordecai P Blaustein, Nisha Charkoudian, Igor R Efimov, David D Gutterman, David A Kass, Yulin Liao, Donal S O'Leary, Crystal May Ripplinger, Michael S Wolin
n/a.
June 16, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28483061/corrigendum-to-treatment-of-right-heart-thrombi-associated-with-acute-pulmonary-embolism-american-journal-of-medicine-130-2017-588-595
#3
Deisy Barrios, Jeremy Chavant, David Jiménez, Laurent Bertoletti, Vladimir Rosa-Salazar, Alfonso Muriel, Alain Viallon, Carmen Fernández-Capitán, Roger D Yusen, Manuel Monreal
No abstract text is available yet for this article.
May 5, 2017: American Journal of Medicine
https://www.readbyqxmd.com/read/28473092/acr-appropriateness-criteria-%C3%A2-suspected-pulmonary-hypertension
#4
Arlene Sirajuddin, Edwin F Donnelly, Traves P Crabtree, Travis S Henry, Mark D Iannettoni, Geoffrey B Johnson, Ella A Kazerooni, Fabien Maldonado, Kathryn M Olsen, Carol C Wu, Tan-Lucien Mohammed, Jeffrey P Kanne
Pulmonary hypertension may be idiopathic or related to a large variety of diseases. Various imaging examinations that may be helpful in diagnosing and determining the etiology of pulmonary hypertension are discussed. Imaging examinations that may aid in the diagnosis of pulmonary hypertension include chest radiography, ultrasound echocardiography, ventilation/perfusion scans, CT, MRI, right heart catheterization, pulmonary angiography, and fluorine-18-2-fluoro-2-deoxy-d-glucose PET/CT. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28473073/acr-appropriateness-criteria-%C3%A2-known-or-suspected-congenital-heart-disease-in-the-adult
#5
Pamela K Woodard, Vincent B Ho, Scott R Akers, Garth Beache, Richard K J Brown, Kristopher W Cummings, S Bruce Greenberg, James K Min, Arthur E Stillman, Jadranka Stojanovska, Jill E Jacobs
The incidence of congenital heart disease (CHD) has been increasing in the adult patient population in part as a result of better patient survival. Patients with more severe CHD are living longer. Nearly all adults with known CHD require periodic imaging as a means of monitoring their disease process. Furthermore, adult patients with suspected CHD require imaging as a means of definitive diagnosis. As a result, it is important for both the referring clinician and the imager to be aware of the most appropriate imaging modality needed to obtain the data most needed to direct the next steps in patient care...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28473068/acr-appropriateness-criteria-%C3%A2-dyspnea-suspected-cardiac-origin
#6
Jens Vogel-Claussen, Amany S M Elshafee, Jacobo Kirsch, Richard K J Brown, Lynne M Hurwitz, Cylen Javidan-Nejad, Paul R Julsrud, Christopher M Kramer, Rajesh Krishnamurthy, Archana T Laroia, Jonathon A Leipsic, Kalpesh K Panchal, Amar B Shah, Richard D White, Pamela K Woodard, Suhny Abbara
This article discusses imaging guidelines for five dyspnea variants: (1) dyspnea due to heart failure, ischemia not excluded; (2) dyspnea due to suspected nonischemic heart failure, ischemia excluded; (3) dyspnea due to suspected valvular heart disease, ischemia excluded; (4) dyspnea due to suspected cardiac arrhythmia, ischemia excluded; and (5) dyspnea due to suspected pericardial disease, ischemia excluded. The American College of Radiology Appropriateness Criteria are evidence-based guidelines for specific clinical conditions that are reviewed annually by a multidisciplinary expert panel...
May 2017: Journal of the American College of Radiology: JACR
https://www.readbyqxmd.com/read/28466573/calcium-supplementation-and-cardiovascular-risk-a-rising-concern
#7
REVIEW
Aurel T Tankeu, Valirie Ndip Agbor, Jean Jacques Noubiap
Over the past decade, the number of individuals taking calcium supplementation worldwide has been on the rise, especially with the emergence of new pharmaceutical companies specialized in the marketing of dietary supplements; with calcium supplementation being their main business axis. This is mostly because of the established role of calcium in the prevention and treatment of osteoporosis and, to a lesser extent, its role in the prevention of fractures. Recently, a rising body of evidence on the adverse effect of calcium supplementation on nonskeletal, especially cardiovascular, health has been a cause for concern...
May 2, 2017: Journal of Clinical Hypertension
https://www.readbyqxmd.com/read/28446526/impact-of-different-dietary-approaches-on-blood-pressure-in-hypertensive-and-prehypertensive-patients-protocol-for-a-systematic-review-and-network-meta-analysis
#8
Lukas Schwingshackl, Anna Chaimani, Georg Hoffmann, Carolina Schwedhelm, Heiner Boeing
INTRODUCTION: Lifestyle modification is one of the cornerstones in the management of hypertension. According to the most recent guidelines by the American Heart Association, all patients with hypertension should adopt the following dietary advices: increased consumption of fresh fruits, vegetables, low-fat dairy products and sodium reduction. The aim of the present study is to assess the efficacy of different dietary approaches on systolic and diastolic blood pressure in patients with hypertension and high normal blood pressure in a systematic review including a pairwise and network meta-analysis of randomised trials...
April 26, 2017: BMJ Open
https://www.readbyqxmd.com/read/28314759/guidelines-in-cardiovascular-research-a-first-for-the-american-journal-of-physiology-heart-and-circulatory-physiology
#9
Irving H Zucker
not applicable for editorial.
March 17, 2017: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/28262974/when-research-unravels-one-community-psychologist-s-tale-of-becoming-a-nepantlera
#10
Janelle M Silva
This is an autoethnography of one community psychologist's reflections on the abrupt conclusion of a project that resulted in the dismantlement of a Latinx Student Union at a public middle school in the Pacific Northwest. Gloria Anzaldúa's (Borderlands/La Frontera: The new mestiza, Aunt Lute Books, San Francisco, 2002) notion of nepantla is used to situate how an individual's personal identities often intersects with their professional identities in ways that collide within the research environment. Drawing on the "heart work" core competencies within the field of community psychology (The Community Psychologist, 45, 2012, 8; American Journal of Community Psychology, 55, 2015, 266) and extending the dialogue of feminist community psychologists engaged in narrative work (American Journal of Community Psychology, 37, 2006, 157; American Journal of Community Psychology, 37, 2006, 267; Feminist research practice: A primer, Sage, Los Angeles, 2014; American Journal of Community Psychology, 28, 2000, 883), the author addresses why it is important for researchers of Color engaged in community collaborations to reflect on projects that have unraveled to understand how their positionality shifts within social contexts...
March 6, 2017: American Journal of Community Psychology
https://www.readbyqxmd.com/read/28124682/psychosocial-correlates-of-apparent-treatment-resistant-hypertension-in-the-jackson-heart-study
#11
A J Shallcross, M Butler, R M Tanner, A P Bress, P Muntner, D Shimbo, G Ogedegbe, M Sims, T M Spruill
Apparent treatment-resistant hypertension (aTRH) is associated with adverse cardiovascular outcomes. aTRH is common and disproportionately affects African Americans. The objective of this study is to explore psychosocial correlates of aTRH in a population-based cohort of African Americans with hypertension. The sample included 1392 participants in the Jackson Heart Study with treated hypertension who reported being adherent to their antihypertensive medications. aTRH was defined as uncontrolled clinic BP (⩾140/90 mm Hg) with ⩾3 classes of antihypertensive medication or treatment with ⩾4 classes of antihypertensive medication, including a diuretic...
July 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/27831548/a-novel-more-efficient-staged-approach-for-critical-congenital-heart-disease-screening
#12
J Mouledoux, S Guerra, J Ballweg, Y Li, W Walsh
OBJECTIVE: Screening for critical congenital heart disease (CCHD) using pulse oximetry has been endorsed by the American Academy of Pediatrics and the American Heart Association. The recommended screening requires two saturation readings. We sought to determine the incidence of undetected CCHD in Tennessee for the 2 years following implementation of an algorithm that assigned an immediate pass to a single lower extremity saturation of 97% or higher. STUDY DESIGN: State Genetic Screening records and reports of missed cases from the Tennessee Initiative for Perinatal Quality Care were used to determine if CCHD cases were missed by the new screening algorithm...
March 2017: Journal of Perinatology: Official Journal of the California Perinatal Association
https://www.readbyqxmd.com/read/27670935/determination-of-gestational-time-and-prediction-of-parturition-in-dogs-and-cats-an-update
#13
M Beccaglia, S Alonge, C Trovo', G C Luvoni
Accurate prediction of delivery date in canine and feline allows a better management of parturition, reducing the loss of neonates. This review evaluates the most common methods adopted to accurately predict the day of delivery: determination of ovulation and hormonal assays, first appearance of embryonic/foetal structures using ultrasound or radiography, echographic measurement of extra-foetal and foetal structures, or evaluation of foetal flux and heart rate. Determination of ovulation and hormonal assays at the time of breeding and close to pregnancy term is widely used to predict parturition in dogs (Concannon et al...
September 2016: Reproduction in Domestic Animals, Zuchthygiene
https://www.readbyqxmd.com/read/27629244/cadmium-body-burden-and-increased-blood-pressure-in-middle-aged-american-indians-the-strong-heart-study
#14
N Franceschini, R C Fry, P Balakrishnan, A Navas-Acien, C Oliver-Williams, A G Howard, S A Cole, K Haack, E M Lange, B V Howard, L G Best, K A Francesconi, W Goessler, J G Umans, M Tellez-Plaza
Cadmium (Cd) is an environmental pollutant that has been associated with cardiovascular disease in populations, but the relationship of Cd with hypertension has been inconsistent. We studied the association between urinary Cd concentrations, a measure of total body burden, and blood pressure in American Indians, a US population with above national average Cd burden. Urinary Cd was measured using inductively coupled plasma mass spectrometry, and adjusted for urinary creatinine concentration. Among 3714 middle-aged American Indian participants of the Strong Heart Study (mean age 56 years, 41% male, 67% ever-smokers, 23% taking antihypertensive medications), urinary Cd ranged from 0...
March 2017: Journal of Human Hypertension
https://www.readbyqxmd.com/read/27614946/electrocardiographic-indicators-of-acute-coronary-syndrome-are-more-common-in-patients-with-ambulance-transport-compared-to-those-who-self-transport-to-the-emergency-department-journal-of-electrocardiology
#15
Jessica K Zègre-Hemsey, David Pickham, Michele M Pelter
INTRODUCTION: The American Heart Association recommends individuals with symptoms suggestive of acute coronary syndrome (ACS) activate the Emergency Medical Services' (EMS) 911 system for ambulance transport to the emergency department (ED), which enables treatment to begin prior to hospital arrival. Despite this recommendation, the majority of patients with symptoms suspicious of ACS continue to self-transport to the ED. The IMMEDIATE AIM study was a prospective study that enrolled individuals who presented to the ED with ischemic symptoms...
November 2016: Journal of Electrocardiology
https://www.readbyqxmd.com/read/27598271/outcomes-of-an-interdisciplinary-transitional-care-quality-improvement-project-on-self-management-and-health-care-use-in-patients-with-heart-failure
#16
Carrie Hoover, Joy Plamann, Jean Beckel
Heart failure (HF) accounts for most U.S. Medicare hospital admissions. The purpose of the current study was to evaluate the effectiveness of a care transitions quality improvement (QI) intervention on self-management and readmission rates in older adults with HF. A quasi-experimental, descriptive study was conducted with 66 patients with HF in three medical units in a 489-bed Midwestern acute care hospital. The intervention included a nurse coach visit and follow up, pharmacy medication education and reconciliation, and HF clinic referral...
January 1, 2017: Journal of Gerontological Nursing
https://www.readbyqxmd.com/read/27257737/reporting-of-randomized-controlled-trials-with-statistically-nonsignificant-primary-outcomes-published-in-high-impact-surgical-journals
#17
Lakshmanan Arunachalam, Iain A Hunter, Shane Killeen
OBJECTIVE: To determine the nature and frequency of distorted presentation or "spin" (ie, specific reporting strategies which highlight that the experimental treatment is beneficial, despite a statistically nonsignificant difference for the primary outcome, or distract the reader from statistically nonsignificant results) in published reports of randomized controlled trials (RCTs) with statistically nonsignificant results for primary outcomes in surgical journals. BACKGROUND: Multiple reports have suggested that interpretation of RCT results in medical journals can be distorted by authors of published reports...
June 2017: Annals of Surgery
https://www.readbyqxmd.com/read/27179741/corrigendum-to-the-brazilian-cardioprotective-nutritional-program-to-reduce-events-and-risk-factors-in-secondary-prevention-for-cardiovascular-disease-study-protocol-the-balance-program-trial-american-heart-journal-171-1-2016-73-81
#18
Bernardete Weber, Ângela C Bersch-Ferreira, Camila R Torreglosa, Maria B Ross-Fernandes, Jacqueline T da Silva, Andrea P Galante, Enilda de Sousa Lara, Rosana P Costa, Rafael M Soares, Alexandre B Cavalcanti, Emilio H Moriguchi, Neide M Bruscato, Josiele Kesties, Lilian Vivian, Marina Schumacher, Waldemar de Carli, Luciano M Backes, Bruna R Reolão, Milena P Rodrigues, Dúnnia M B Baldissera, Glaucia S Tres, Hugo R K Lisbôa, João B J Bem, Jose B C Reolão, Keyla L A L Deucher, Maiara Cantarelli, Aline Lucion, Daniela Rampazzo, Vanessa Bertoni, Rosileide S Torres, Adriana O L Verríssimo, Aldair S Guterres, Andrea F R Cardos, Dalva B S Coutinho, Mayara G Negrão, Mônica F A Alencar, Priscila M Pinho, Socorro N A A Barbosa, Ana P P F Carvalho, Maria I S Taboada, Sheila A Pereira, Raul V Heyde, Francisca E Z Nagano, Rebecca Baumgartner, Fernanda P Resende, Ranata Tabalipa, Ana C Zanini, Michael J R Machado, Hevila Araujo, Maria L V Teixeira, Gabriela C Souza, Priccila Zuchinali, Bianca M Fracasso, Karen Ulliam, Marina Schumacher, Moara Pierotto, Thamires Hilário, Daniele M O Carlos, Cintia G N C Cordeiro, Daniele A Carvalho, Marília S Gonçalves, Valdiana B Vasconcelos, Rosa Bosquetti, Raira Pagano, Marcelo L P Romano, César A Jardim, Bernardo N A de Abreu, Aline Marcadenti, Alessandra R Schmitt, Angela M V Tavares, Christiane C Faria, Flávia M Silva, Jaqueline S Fink, Raquel M El Kik, Clarice F Prates, Cristiane S Vieira, Elaine F Adorne, Ellen H Magedanz, Fernanda L Chieza, Ingrid S Silva, Joise M Teixeira, Eduardo P Trescastro, Lívia A Pellegrini, Jéssika C Pinto, Cristina T Telles, Antonio C S Sousa, Andreza S Almeida, Ariane A Costa, José A C Carmo, Juliana T Silva, Luciana V S Alves, Saulo O C Sales, Maria E M Ramos, Marilia C S Lucas, Monica Damiani, Patricia C Cardoso, Salvador S Ramos, Clenise F Dantas, Amanda G Lopes, Ana M P Cabral, Ana C A Lucena, Auriene L Medeiros, Bernardino B Terceiro, Neuma M F S Leda, Sandra R D Baía, Josilene M F Pinheiro, Alexandra N Cassiano, Andressa N L Melo, Anny K O Cavalcanti, Camila V S Souza, Dayanna J M Queiroz, Hercilla N C F Farias, Larissa C F Souza, Letícia S Santos, Luana R M Lima, Meg S Hoffmann, Átala S Silva Ribeiro, Daniel F Vasconcelos, Eliane S Dutra, Marina K Ito, José A F Neto, Alexsandro F Santos, Rosângela M L Sousa, Luciana Pereira P Dias, Maria T M A Lima, Victor G Modanesi, Adriana F Teixeira, Luciana C N C D Estrada, Paulo V G Modanesi, Adriana B L Gomes, Bárbara R S Rocha, Cristina Teti, Marta M David, Bruna M Palácio, Délcio G S Junior, Érica H S Faria, Michelle C F Oliveira, Rose M Uehara, Sandramara Sasso, Annie S B Moreira, Ana C A H Cadinha, Carla W M Pinto, Mariana P Castilhos, Mariana Costa, Cristiane Kovacs, Daniel Magnoni, Quênia Silva, Michele F C A Germini, Renata A da Silva, Aline S Monteiro, Karina G Dos Santos, Priscila Moreira, Fernanda C Amparo, Catharina C J Paiva, Soraia Poloni, Diana S Russo, Izabele V Silveira, Maria A Moraes, Mirena Boklis, Quinto I Cardoso, Annie S B Moreira, Aline M S Damaceno, Elisa M Santos, Glauber M Dias, Cláudia P S Pinho, Adrilene C Cavalcanti, Amanda S Bezerra, Andrey V Queiroga, Isa G Rodrigues, Tallita V Leal, Viviane Sahade, Daniele A Amaral, Diana S Souza, Givaldo A Araújo, Karine Curvello, Manuella Heine, Marília M S Barretto, Nailson A Reis, Sandra M L Vasconcelos, Danielly C Vieira, Francisco A Costa, Jessica M S Fontes, Juvenal G C Neto, Laís N P Navarro, Raphaela C Ferreira, Patrícia M Marinho, Renata Torres Abib, Aline Longo, Eduardo G Bertoldi, Lauren S Ferreira, Lúcia R Borges, Norlai A Azevedo, Celma M Martins, Juliana T Kato, Maria C O Izar, Marina T Asoo, Mariana D de Capitani, Valéria A Machado, Waléria T Fonzar, Sônia L Pinto, Kellen C Silva, Lúcia H A Gratão, Sheila D Machado, Susane R U de Oliveira, Josefina Bressan, Ana P S Caldas, Hatanne C F M Lima, Helen H M Hermsdorff, Tânia M Saldanha, Sílvia E Priore, Naoel H Feres, Adila de Queiroz Neves, Loanda M G Cheim, Nilma F Silva, Silvia R L Reis, Andreza M Penafort, Ana Paula O de Queirós, Geysa M N Farias, Mônica L P de Los Santos, Cíntia L Ambrozio, Cirília N Camejo, Cristiano P Dos Santos, Gabriela S Schirmann, Jorge L Boemo, Rosane E C Oliveira, Súsi M B Lima, Vera M S Bortolini, Cristina H Matos, Claiza Barretta, Clarice M Specht, Simone R de Souza, Cristina S Arruda, Priscila A Rodrigues, Otávio Berwanger
No abstract text is available yet for this article.
May 2016: American Heart Journal
https://www.readbyqxmd.com/read/27169827/ambulatory-blood-pressure-monitoring-phenotypes-among-individuals-with-and-without-diabetes-taking-antihypertensive-medication-the-jackson-heart-study
#19
S G Bromfield, D Shimbo, A G Bertoni, M Sims, A P Carson, P Muntner
Ambulatory blood pressure monitoring (ABPM) can detect phenotypes associated with increased cardiovascular disease (CVD) risk. Diabetes is associated with increased CVD risk but few data are available documenting whether blood pressure (BP) phenotypes, detected by ABPM, differ between individuals with versus without diabetes. We conducted a cross-sectional analysis of 567 participants in the Jackson Heart Study, a population-based study of African Americans, taking antihypertensive medication to evaluate the association between diabetes and ABPM phenotypes...
December 2016: Journal of Human Hypertension
https://www.readbyqxmd.com/read/27103157/erratum-for-tecson-et%C3%A2-al-impact-of-enhanced-external-counterpulsation-on-heart-failure-rehospitalization-in-patients-with-ischemic-cardiomyopathy-american-journal-of-cardiology-am-j-cardiol-2016-117-901-905
#20
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