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oportunistic infections

Azusa Takahashi-Nakaguchi, Kanae Sakai, Hiroki Takahashi, Daisuke Hagiwara, Takahito Toyotome, Hiroji Chibana, Akira Watanabe, Takashi Yaguchi, Masashi Yamaguchi, Katsuhiko Kamei, Tohru Gonoi
Aspergillus fumigatus is an important fungal pathogen of humans. Inhaled conidia of A. fumigatus adhere to pulmonary epithelial cells, causing opportunistic infection. However, little is known about the molecular mechanism of the adherence of resting conidia. Fungal molecules adhesive to host cells are presumed to be displayed on the conidial surface during conidial formation as a result of changes in gene expression. Therefore, we exhaustively searched for adhesion molecules by comparing the phenotypes and the gene expression profiles of A...
March 2018: Cellular Microbiology
R Cossío-Bayúgar, E Miranda-Miranda, C A Arreguín-Pérez, L Lozano, D Peréz de la Rosa, M K Rocha-Martínez, M A Bravo-Díaz, B Sachman-Ruiz
Enterococcus spp. are Gram-positive lactic acid-producing bacteria found in the intestinal tracts of animals, like mammals, birds, and arthropods. Enterococcus spp. may cause oportunistic infections in vertebrate and invertebrate hosts. We report here the draft genome sequence of Enterococcus casseliflavus PAVET15 containing 3,722,480 bp, with 80 contigs, an N50 of 179,476 bp, and 41.93% G+C content.
April 20, 2017: Genome Announcements
Denise C Arruda, Alisson L Matsuo, Luiz S Silva, Fernando Real, Natanael P Leitão, Jhon H S Pires, Antonio Carlos F Caires, Daniel M Garcia, Fernanda F M Cunha, Rosana Puccia, Larissa V G Longo
Paracoccidioidomycosis (PCM), caused by Paracoccidioides species, is the main cause of death due to systemic mycoses in Brazil and other Latin American countries. Therapeutic options for PCM and other systemic mycoses are limited and time-consuming, and there are high rates of noncompliance, relapses, toxic side effects, and sequelae. Previous work has shown that the cyclopalladated 7a compound is effective in treating several kinds of cancer and parasitic Chagas disease without significant toxicity in animals...
December 2015: Antimicrobial Agents and Chemotherapy
R Nawrot, K Kamieniarz, M Malinowska, A Józefiak, W Kedzia, A Kwaśniewska, D Kuźma, A Goździcka-Józefiak
UNLABELLED: The aim of the present study was to determine the prevalence of Leptotrichia amnionii in cervical swabs of women and its possible correlation with HPV infection and the stage of cervical cancer. MATERIAL AND METHODS: A total of 139 cervical swabs from healthy women with normal cytology, with dysplastic changes and with cervical cancer were tested for the presence of L.amnionii and high-risk HPV DNA by PCR methods. RESULTS: L. amnionii was found in normal vaginal flora and in women with bacterial vaginosis (BV), which suggests that it may be oportunistic pathogen...
2010: European Journal of Gynaecological Oncology
Javier González Martín-Moro, Jose María López-Arcas Calleja, Miguel Burgueño García, Jose Luis Cebrián Carretero, Julio García Rodríguez
Mucormycosis is a rare oportunistic infection typically described in diabetic patients with a ketoacidotic status, as well as neutropenic patients. The infection is caused by a group of saprophytic fungi of the class Phycomicetes, being the most frequent ones the Rhizomucor, Rhizopus and Mucor. Its hystological findings include vascular trombosis and tissue necrosis, predominantly in the rino-orbito-cerebral area. Even though the frequency of presentation is very low, given its rapid evolution and severe consequences which include a high mortality rate, it is very important to be aware of the main features of the disease and treat it promptly...
December 2008: Medicina Oral, Patología Oral y Cirugía Bucal
D Salemović, Dj Jevtović, B Brmbolić, J Ranin, M Tucaković
The primary causes of morbidity and mortality in persons infected with the human immunodoficiency virus are oportunistic infections. Infection with the human immunodeficiency virus (HIV) induces progressive quantitative and qualitative defects in CD4 (T helper) lymphocytes. Macrophage and monocyte function may also be impaired as a result of HIV infection. Consequently, patients in the later stages of HIV infection (ARC and AIDS) frequently experiency infections against which either cellular od humoral immunity, or both, are important...
November 1992: Srpski Arhiv za Celokupno Lekarstvo
H A Teive, A R Troiano, N L Cabral, N Becker, L C Werneck
Movement disorders are not common in acquired immunodeficiency syndrome. Hemichorea-hemiballism (HC-HB) is the most common of them all, and it is usually related to oportunistic toxoplasmosis of the basal ganglia. We present a 28-year-old man, HIV positive with HC-HB caused by a right subthalamic granuloma, which did not respond to treatment for toxoplasmosis. Cryptoccococic antigen was positive in the cerebrospinal fluid and antifungic therapy led to clinical and radiologic improvement, thus the diagnosis of a granulomatous lesion by Cryptococcus neoformans was established...
September 2000: Arquivos de Neuro-psiquiatria
J C Guilbeau, J Frija, E Gluckman, O Verola, C Brocheriou, M Laval-Jeantet
The case of a 42 years old man who had a monoblastic acute leukemia treated by a bone-marrow graft is described. The patient died of a cerebral toxoplasmosis and a cerebral computed tomography done two days before is correlated with anatomopathologic slices done in the same planes than the computed tomagraphy examination. There is a good correlation between necrotic abceded areas and hypodense areas accompanied by serpiginous fixations of contrast media. The immunocompromised patient is very favorable for the development of a cerebral toxoplasmosis...
May 1983: Journal de Radiologie
M Scaff, G D Rabello, P E Marchiori
A 50-year-old man with positive test for human immunodeficiency virus (HIV) by enzyme-linked-immunoassy and Western-blot, without clinical manifestations of acquired immunodeficiency syndrome (AIDS), developed acute polyradiculoneuritis and was treated by plasmapheresis with improvement. We believe that chemical homologies of antigenic determinants between HIV and P2 protein of peripheral nervous system and myelin basic protein may induce crossed-reaction, thus developing acute polyradiculoneuritis and central nervous system involvement, respectively...
March 1989: Arquivos de Neuro-psiquiatria
I Mezzaroma, A Avella, R Paganelli, B Ensoli, G d'Offizi, M C Sirianni, G Luzi, C Valdarchi, F Aiuti
We evaluated clinical efficacy and tolerability of recombinant alpha 2a interferon (IFN), in a group of 16 patients with AIDS and ARC, including 3 children. All patients were followed up monthly for clinical and immunological studies. The frequency of oportunistic infections (OI) in AIDS, and the following symptoms in all patients were studied: fever, night sweats, fatigue, diarrhoea, weight loss. Immunological parameters (CD3+, CD4+, CD8+ lymphocytes, skin tests to recall antigens, NK activity, lymphoproliferative response to PHA) were also evaluated...
September 1991: Allergologia et Immunopathologia
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