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Cognitive—Communicative Disorders

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https://www.readbyqxmd.com/read/28743064/health-status-and-mobility-limitations-are-associated-with-residential-and-employment-status-in-schizophrenia-and-bipolar-disorder
#1
M Strassnig, D Cornacchio, P D Harvey, R Kotov, L Fochtmann, E J Bromet
INTRODUCTION: Schizophrenia (SCZ) and bipolar disorder (BP) are linked to multiple impairments in everyday functioning which share cognitive and symptom risk factors. Other risk factors for critical aspects of every day functioning (e.g., gainful employment; residential independence) such as physical health have not been evaluated, despite poor health in SCZ and BP. METHODS: We analyzed 20-year follow-up data from the Suffolk County Mental Health Project cohort of consecutive first admissions with a psychotic disorder to 12 psychiatric facilities in Suffolk County, NY, between September 1989 and December 1995...
July 18, 2017: Journal of Psychiatric Research
https://www.readbyqxmd.com/read/28743059/altered-connectivity-within-and-between-the-default-mode-central-executive-and-salience-networks-in-obsessive-compulsive-disorder
#2
Jie Fan, Mingtian Zhong, Jun Gan, Wanting Liu, Chaoyang Niu, Haiyan Liao, Hongchun Zhang, Jinyao Yi, Raymond C K Chan, Changlian Tan, Xiongzhao Zhu
BACKGROUND: Default mode network (DMN), central executive network (CEN) and salience network (SN) are the three most important intrinsic networks of the human brain. Recent studies emphasized the importance of the "triple-network model" which illustrated the interactions within and between DMN, CEN and SN in the pathophysiology of psychiatric disorders. However, previous studies of obsessive-compulsive disorder (OCD) just explored the altered connectivity within these networks while neglected the coupling between them...
July 20, 2017: Journal of Affective Disorders
https://www.readbyqxmd.com/read/28742932/a-pilot-randomized-clinical-trial-testing-integrated-twelve-step-facilitation-itsf-treatment-for-adolescent-substance-use-disorder
#3
John F Kelly, Yifrah Kaminer, Christopher W Kahler, Bettina Hoeppner, Julie Yeterian, Julie V Cristello, Christine Timko
BACKGROUND AND AIMS: Integration of 12-step philosophy and practices is common in adolescent substance use disorder (SUD) treatment programs, particularly in North America. However, although numerous experimental studies have tested 12-step facilitation (TSF) treatments among adults, no studies have tested TSF-specific treatments for adolescents. We tested the efficacy of a novel integrated TSF. DESIGN: Explanatory, parallel-group, randomized clinical trial comparing 10 sessions of either motivational enhancement therapy/cognitive-behavioral therapy (MET/CBT; n=30) or a novel integrated TSF (iTSF; n=29) with follow-up assessments at 3-, 6-, and 9-months following treatment entry...
July 25, 2017: Addiction
https://www.readbyqxmd.com/read/28742625/online-sales-of-unscheduled-pharmaceutical-agents-a-case-report-of-tianeptine-use-in-the-united-states
#4
Swapnil Gupta, Ryan Wallace, Jordan Sloshower
: Tianeptine is a tricyclic antidepressant that stimulates mu-opioid receptors at high doses. It is marketed and used across Europe and Latin America as an antidepressant, but is not approved by the Food and Drug Administration for use in the United States. In the United States, tianeptine is sold through online health stores as a cognition enhancer, dietary supplement, or as research chemical. We report the case of a 36-year-old man with a history of major depressive disorder, responsive to sertraline, who turned to the unmonitored use of tianeptine purchased online to treat residual feelings of apathy and boredom...
July 24, 2017: Journal of Addiction Medicine
https://www.readbyqxmd.com/read/28742290/infant-related-intrusive-thoughts-of-harm-in-the-postpartum-period-a-critical-review
#5
Elke C Brok, Patricia Lok, Desiree B Oosterbaan, Aart H Schene, Indira Tendolkar, Philip F van Eijndhoven
BACKGROUND: Besides the expected warm and joyful thoughts, a new mother can be disturbed by sudden frightening thoughts or images of harm done to her baby: harming intrusions, an obsessive phenomenon. Its high prevalence and possible consequences in functioning and in mother-child bonding makes it desirable that clinicians are well informed regarding the current state of knowledge about harming intrusions. OBJECTIVE: To provide a comprehensive review of all studies that have investigated harming intrusions in postpartum women...
July 18, 2017: Journal of Clinical Psychiatry
https://www.readbyqxmd.com/read/28742136/can-a-tablet-based-cancellation-test-identify-cognitive-impairment-in-older-adults
#6
Ya-Huei Wu, Jean-Sébastien Vidal, Jocelyne de Rotrou, Sietske A M Sikkes, Anne-Sophie Rigaud, Matthieu Plichart
BACKGROUND AND OBJECTIVE: There has been a growing interest in using computerized cognitive assessment to detect age-related cognitive disorders. We have developed a tablet-based cancellation test (e-CT), previously shown as a reliable measure of executive functions and free of effect of familiarity with computer-based devices in healthy older adults. This study aimed to investigate the influence of demographics and current daily use of computer-based devices in older adults with Mild Cognitive Impairment (MCI) and Alzheimer's disease (AD)...
2017: PloS One
https://www.readbyqxmd.com/read/28742080/emergent-remitted-and-persistent-psychosis-spectrum-symptoms-in-22q11-2-deletion-syndrome
#7
S X Tang, T M Moore, M E Calkins, J J Yi, D M McDonald-McGinn, E H Zackai, B S Emanuel, R C Gur, R E Gur
Individuals with 22q11.2 deletion syndrome (22q11DS) are at markedly elevated risk for schizophrenia-related disorders. Stability, emergence, remission and persistence of psychosis-spectrum symptoms were investigated longitudinally. Demographic, clinical and cognitive predictors of psychosis were assessed. Prospective follow-up over 2.8 years was undertaken in 75 individuals with 22q11DS aged 8-35 years. Mood, anxiety, attention-deficit hyperactivity disorders and psychosis-spectrum symptoms were assessed with the Kiddie-Schedule for Affective Disorders and Schizophrenia and Scale of Prodromal Symptoms (SOPS)...
July 25, 2017: Translational Psychiatry
https://www.readbyqxmd.com/read/28741736/increased-mindfulness-skills-as-predictors-of-reduced-trauma-related-guilt-in-treatment-seeking-veterans
#8
Philip Held, Gina P Owens, J Richard Monroe, Kathleen M Chard
The present study examined the predictive role of increased self-reported mindfulness skills on reduced trauma-related guilt in a sample of veterans over the course of residential treatment for posttraumatic stress disorder (PTSD; N = 128). The residential treatment consisted of seven weeks of intensive cognitive processing therapy (CPT) for PTSD, as well as additional psychoeducational groups, including seven sessions on mindfulness skills. Increased mindfulness skills describing, acting with awareness, and accepting without judgment were significantly associated with reductions in trauma-related guilt over the course of treatment...
July 25, 2017: Journal of Traumatic Stress
https://www.readbyqxmd.com/read/28741714/abnormal-fronto-parietal-white-matter-organisation-in-the-superior-longitudinal-fasciculus-branches-in-autism-spectrum-disorders
#9
Jacqueline Fitzgerald, Alexander Leemans, Elizabeth Kehoe, Erik O'Hanlon, Louise Gallagher, Jane McGrath
Core features of ASD may be underpinned by disrupted functional and structural neural connectivity. Abnormal fronto-parietal functional connectivity has been widely reported in the literature; this may be underpinned by disrupted microstructural organisation of white matter. The Superior Longitudinal Fasciculus (SLF) is a major fronto-parietal white matter tract, the structure of which has been little studied in ASD. The fronto-parietal projections of this tract (SLF I, II and III) are thought to play an important role in a number of cognitive functions including attention and visuospatial processing...
July 25, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28741670/intensive-cognitive-therapy-for-post-traumatic-stress-disorder-in-routine-clinical-practice-a-matched-comparison-audit
#10
Hannah Murray, Sharif El-Leithy, Jo Billings
OBJECTIVES: Intensive cognitive therapy for post-traumatic stress disorder (PTSD) has been shown to be as effective as weekly treatment in controlled trials. In this study, outcome data comparing standard and intensive treatments delivered in routine clinical practice were analysed. METHODS: A consecutive case series of intensive treatment cases were compared to matched control cases who had completed weekly treatment. RESULTS: Both groups showed significant improvements on PTSD and depression measures...
July 25, 2017: British Journal of Clinical Psychology
https://www.readbyqxmd.com/read/28741625/omega-3-polyunsaturated-fatty-acids-in-youths-with-attention-deficit-hyperactivity-disorder-adhd-a-systematic-review-and-meta-analysis-of-clinical-trials-and-biological-studies
#11
JanePei-Chen Chang, Kuan-Pin Su, Valeria Mondelli, Carmine M Pariante
The role of omega-3 polyunsaturated fatty acids (omega-3 or n-3 PUFAs) in the pathogenesis and treatment of children and adolescents with attention deficit hyperactivity disorder (ADHD) is unclear. A systematic review followed by meta-analysis was conducted on: (1) randomized controlled trials (RCTs) assessing the effects of n-3 PUFAs on clinical symptoms and cognition in children and adolescent with ADHD; and (2) case-control studies assessing the levels of n-3 PUFAs in blood and buccal tissues of children and adolescents with ADHD...
July 25, 2017: Neuropsychopharmacology: Official Publication of the American College of Neuropsychopharmacology
https://www.readbyqxmd.com/read/28741437/traumatic-brain-injury-in-a-community-based-cohort-of-homeless-and-vulnerably-housed-individuals
#12
Toby Schmitt, Allen Thornton, Iris Rawtaer, Alasdair Barr, Kristina Gicas, Donna Lang, Talia Vertinsky, Alexander Rauscher, Ric Procyshyn, Tari Buchanan, Alex Cheng, Sarah Mackay, Olga Leonova, Verena Langheimer, Thalia Field, Manraj K S Heran, Fidel Vila-Rodriguez, Tiffany-Anne O'Connor, William MacEwan, William Honer, William Panenka
We characterized traumatic brain injury (TBI) and studied its associations with mental and physical health in a community cohort of homeless and vulnerably-housed individuals. METHODS: Detailed mental and physical health structured interviews, neuropsychological testing, and multimodal MRI were performed on 283 participants. Two traumatic brain injury (TBI) participant groups were defined for primary analyses: those with a self-reported history of TBI and those with MRI evidence of TBI...
July 25, 2017: Journal of Neurotrauma
https://www.readbyqxmd.com/read/28741423/cognitive-control-in-young-adults-with-cannabis-use-disorder-an-event-related-brain-potential-study
#13
David Lr Maij, Ben Jm van de Wetering, Ingmar Ha Franken
Contemporary models of substance use disorders emphasize the role of cognitive control, which has been linked to difficulties in resisting the use of substances. In the present study, we measured two aspects of cognitive control, response inhibition (operationalized by a Go/NoGo Task) and performance monitoring (operationalized by an Eriksen Flanker Task), in a group of young cannabis-use disorder (CUD) patients and compared these functions with two control groups (i.e. a group of cigarette smokers and a group of non-smokers)...
July 1, 2017: Journal of Psychopharmacology
https://www.readbyqxmd.com/read/28741170/decreased-global-field-synchronization-of-multichannel-frontal-eeg-measurements-in-obsessive-compulsive-disorders
#14
Mehmet Akif Özçoban, Oğuz Tan, Serap Aydin, Aydin Akan
Global field synchronization (GFS) quantifies the synchronization level of brain oscillations. The GFS method has been introduced to measure functional synchronization of EEG data in the frequency domain. GFS also detects phase interactions between EEG signals acquired from all of the electrodes. If a considerable amount of local brain neurons has the same phase, these neurons appear to interact with each other. EEG data were received from 17 obsessive-compulsive disorder (OCD) patients and 17 healthy controls (HC)...
July 25, 2017: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/28741144/tobacco-use-and-smoke-exposure-in-children-new-trends-harm-and-strategies-to-improve-health-outcomes
#15
REVIEW
Luv D Makadia, P Jervey Roper, Jeannette O Andrews, Martha S Tingen
PURPOSE OF REVIEW: Every day in the USA, approximately 4000 adolescents begin smoking and the adolescent brain is particularly susceptible to nicotine addiction. We present current pediatric trends on tobacco use and exposures, various new products used by adolescents, the adverse biological and behavioral effects of tobacco use and exposures, and tobacco control strategies to eliminate tobacco-related illnesses and deaths in the pediatric population. RECENT FINDINGS: Twelve-20% of women continue to smoke during pregnancy...
August 2017: Current Allergy and Asthma Reports
https://www.readbyqxmd.com/read/28740870/reduced-ventral-tegmental-area-hippocampal-connectivity-in-children-and-adolescents-exposed-to-early-threat
#16
Hilary A Marusak, Joshua R B Hatfield, Moriah E Thomason, Christine A Rabinak
BACKGROUND: Preclinical data suggest that early life stress has detrimental effects on the brain's dopaminergic system, particularly the mesocorticolimbic pathway. Altered dopamine function is thought to contribute to the development of stress-related pathologies; yet, little is known about the impact of early stress on dopamine systems during childhood and adolescence, when stress-related disorders frequently emerge. Here, we evaluate the impact of early threat exposure (violence, abuse) on functional connectivity of putative dopaminergic midbrain regions, the ventral tegmental area (VTA) and substantia nigra (SN), giving rise to mesocorticolimbic and nigrostriatal pathways, respectively...
March 2017: Biological Psychiatry: Cognitive Neuroscience and Neuroimaging
https://www.readbyqxmd.com/read/28740828/omega-3-fatty-acids-related-to-cognitive-impairment-in-patients-with-schizophrenia
#17
Kazumi Satogami, Shun Takahashi, Shinichi Yamada, Satoshi Ukai, Kazuhiro Shinosaki
Cognitive impairment is strongly associated with functional outcome in patients with schizophrenia but its pathophysiology remains largely unclear. Involvement of omega-3 fatty acids in the cognitive function of healthy individuals and patients with neuropsychiatric disease has received increasing attention. The aim of this study was to examine the relationship between omega-3 fatty acids with cognitive function, social function, and psychiatric symptoms in patients with schizophrenia. The subjects included 30 patients with schizophrenia or schizoaffective disorder...
September 2017: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28740827/self-versus-informant-reports-on-the-specific-levels-of-functioning-scale-relationships-to-depression-and-cognition-in-schizophrenia-and-schizoaffective-disorder
#18
Julia Ermel, Cameron S Carter, James M Gold, Angus W MacDonald, J Daniel Ragland, Steven M Silverstein, Milton E Strauss, Deanna M Barch
The goal of the current study was to examine the relationships between insight and both cognitive function and depression in schizophrenia and schizoaffective disorder, and to determine if there were similar relationships across diagnostic categories. We examined discrepancies between self and informant reports of function on the Specific levels of function scale as a metric of insight for interpersonal, social acceptance, work and activities. We examined two samples of individuals with schizophrenia and/or schizoaffective disorder (Ns of 188 and 67 respectively)...
September 2017: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28740825/nmdar-hypofunction-and-somatostatin-expressing-gabaergic-interneurons-and-receptors-a-newly-identified-correlation-and-its-effects-in-schizophrenia
#19
REVIEW
Fatemah Alherz, Mohammad Alherz, Hashemiah Almusawi
This review investigates the association between N-methyl-d-Aspartate receptor (NMDAR) hypofunction and somatostatin-expressing GABAergic interneurons (SST +) and how it contributes to the cognitive deficits observed in schizophrenia (SZ). This is based on evidence that NMDAR antagonists caused symptoms resembling SZ in healthy individuals. NMDAR hypofunction in GABAergic interneurons results in the modulation of the cortical network oscillation, particularly in the gamma range (30-80 Hz). These gamma-band oscillation (GBO) abnormalities were found to lead to the cognitive deficits observed in the disorder...
June 2017: Schizophrenia Research. Cognition
https://www.readbyqxmd.com/read/28740824/associations-between-daily-living-skills-cognition-and-real-world-functioning-across-stages-of-schizophrenia-a-study-with-the-schizophrenia-cognition-rating-scale-japanese-version
#20
Yuko Higuchi, Tomiki Sumiyoshi, Tomonori Seo, Motomu Suga, Tsutomu Takahashi, Shimako Nishiyama, Yuko Komori, Kiyoto Kasai, Michio Suzuki
Cognitive function is impaired in patients with schizophrenia-spectrum disorders, even in their prodromal stages. Specifically, the assessment of cognitive abilities related to daily-living functioning, or functional capacity, is important to predict long-term outcome. In this study, we sought to determine the validity of the Schizophrenia Cognition Rating Scale (SCoRS) Japanese version, an interview-based measure of cognition relevant to functional capacity (i.e. co-primary measure). For this purpose, we examined the relationship of SCoRS scores with performance on the Brief Assessment of Cognition in Schizophrenia (BACS) Japanese version, a standard neuropsychological test battery, and the Social and Occupational Functioning Assessment Scale (SOFAS), an interview-based social function scale...
March 2017: Schizophrenia Research. Cognition
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