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https://www.readbyqxmd.com/read/28446858/a-case-of-autoimmune-polyglandular-syndrome-ype-2-associated-with-atypical-form-of-scleromyxedema
#1
Oleksander Prylutskyi, Olga Prylutska, Anatoliy Degonskyi, Kseniia Tkachenko
BACKGROUND: Autoimmune polyglandular syndrome type 2 represents an uncommon endocrine disorder composed by Addison's disease with autoimmune thyroid disease (Schmidt's syndrome) and/or type 1 diabetes mellitus. Scleromyxedema is a rare progressive cutaneous mucinosis usually associated with systemic involvement and paraproteinemia. To the best of our knowledge, there is no case report of Schmidt's syndrome associated with scleromyxedema. CASE DETAILS: A 34-year-old woman was admitted to Donetsk Clinical Territorial Medical Association due to acute general weakness, reduced vision, dryness of integuments, memory decline, fatigue, weight loss, rash on the face trunk and extremities...
September 2016: Ethiopian Journal of Health Sciences
https://www.readbyqxmd.com/read/28444832/real-time-activation-of-central-cholinergic-circuits-during-recognition-memory
#2
Sonia Bonnì, Viviana Ponzo, Francesco Di Lorenzo, Carlo Caltagirone, Giacomo Koch
Short Latency Afferent Inhibition (SAI) is a paired-pulse Transcranial Magnetic Stimulation (TMS) protocol that consists in the inhibition of the Motor Evoked Potentials (MEPs) by afferent sensory impulses. SAI is thought to be mediated by cholinergic projections over M1 and can be considered a putative marker of central cholinergic activity. It's known that memory processes are regulated by acetylcholine. Nonetheless the influence of memory tasks on SAI has not been investigated. Here we tested changes in SAI circuits in healthy subjects performing a computerized non-verbal recognition memory task (RMT) requiring to recognize previously encoded faces...
April 26, 2017: European Journal of Neuroscience
https://www.readbyqxmd.com/read/28435123/is-having-similar-eye-movement-patterns-during-face-learning-and-recognition-beneficial-for-recognition-performance-evidence-from-hidden-markov-modeling
#3
Tim Chuk, Antoni B Chan, Janet Hsiao
The hidden Markov model (HMM)-based approach for eye movement analysis is able to reflect individual differences in both spatial and temporal aspects of eye movements. Here we used this approach to understand the relationship between eye movements during face learning and recognition, and its association with recognition performance. We discovered holistic (i.e., mainly looking at the face center) and analytic (i.e., specifically looking at the two eyes in addition to the face center) patterns during both learning and recognition...
April 20, 2017: Vision Research
https://www.readbyqxmd.com/read/28430039/distractor-resistant-stm-is-supported-by-transient-changes-in-neural-stimulus-representations
#4
Jan Derrfuss, Matthias Ekman, Michael Hanke, Marc Tittgemeyer, Christian J Fiebach
Goal-directed behavior in a complex world requires the maintenance of goal-relevant information despite multiple sources of distraction. However, the brain mechanisms underlying distractor-resistant working or STM are not fully understood. Although early single-unit recordings in monkeys and fMRI studies in humans pointed to an involvement of lateral prefrontal cortices, more recent studies highlighted the importance of posterior cortices for the active maintenance of visual information also in the presence of distraction...
April 21, 2017: Journal of Cognitive Neuroscience
https://www.readbyqxmd.com/read/28422578/korean-version-of-the-mini-mental-state-examination-using-smartphone-a-validation-study
#5
Hae-Yeon Park, Sung-Soo Jeon, Jin-Youn Lee, Ah-Ra Cho, Joo Hyun Park
BACKGROUND: Stroke often leads to disability, and poststroke survivors often have limited accessibility to medical facilities. INTRODUCTION: For such patients, mobile videoconferencing technology offers an opportunity to perform follow-up assessment and appropriate management of cognitive impairment. We aimed to determine the validity of the Korean version of the Mini-Mental State Examination (MMSE-K) when administered using a smartphone. MATERIALS AND METHODS: Thirty patients with ischemic or hemorrhagic stroke were included in this study (20 males, 10 females; mean age, 69...
April 19, 2017: Telemedicine Journal and E-health: the Official Journal of the American Telemedicine Association
https://www.readbyqxmd.com/read/28421717/cognitive-profiles-in-euthymic-patients-with-bipolar-disorders-results-from-the-face-bd-cohort
#6
Paul Roux, Aurélie Raust, Anne Sophie Cannavo, Valérie Aubin, Bruno Aouizerate, Jean-Michel Azorin, Frank Bellivier, Raoul Belzeaux, Thierry Bougerol, Iréna Cussac, Philippe Courtet, Bruno Etain, Sébastien Gard, Sophie Job, Jean-Pierre Kahn, Marion Leboyer, Emilie Olié, Chantal Henry, Christine Passerieux
OBJECTIVES: Although cognitive deficits are a well-established feature of bipolar disorders (BD), even during periods of euthymia, little is known about cognitive phenotype heterogeneity among patients with BD. METHODS: We investigated neuropsychological performance in 258 euthymic patients with BD recruited via the French network of expert centers for BD. We used a test battery assessing six domains of cognition. Hierarchical cluster analysis of the cross-sectional data was used to determine the optimal number of subgroups and to assign each patient to a specific cognitive cluster...
April 19, 2017: Bipolar Disorders
https://www.readbyqxmd.com/read/28419918/internal-shifting-impairments-in-response-to-emotional-information-in-dysphoric-adolescents
#7
Laura Wante, Sven C Mueller, Ineke Demeyer, Tiffany Naets, Caroline Braet
BACKGROUND AND OBJECTIVES: Previous studies have suggested that internal cognitive control impairments may play an important role in the development of depression. Despite a growing body of research in adults, the ability to shift internal attention between mental representations in working memory has received little attention in younger populations. This study investigated internal shifting capacity between emotional and non-emotional information in dysphoric and non-dysphoric adolescents...
April 13, 2017: Journal of Behavior Therapy and Experimental Psychiatry
https://www.readbyqxmd.com/read/28411522/breaking-the-age-barrier-epilepsy-surgery-in-septuagenarians
#8
Vineet Punia, Ahmed Abdelkader, Andrey Stojic
Resective epilepsy surgery (RES) has traditionally been offered to young patients (<50years). The reservation about offering RES to the elderly is multifactorial with their advanced age and comorbidities being the primary reason. The elderly age group (≥65years of age) is one of the fastest growing populations. The arbitrary age limits for RES need reconsideration in the face of an ever increasing elderly population. Considering such changes in demographics, we report the first case series in the literature of seven septuagenarians who underwent RES in the form of anterior temporal lobectomy (ATL)...
April 12, 2017: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/28406664/spontaneous-retrieval-deficits-in-amnestic-mild-cognitive-impairment-a-case-of-focal-event-based-prospective-memory
#9
Agnieszka Niedźwieńska, Lia Kvavilashvili, Kunle Ashaye, Jacek Neckar
OBJECTIVE: Research on early cognitive markers of Alzheimer's disease is primarily focused on retrospective recall (of word lists, pairs of items, stories) and executive functions. However, research shows that people with amnestic mild cognitive impairment (aMCI), who are at a higher risk of developing the disease than healthy controls, are particularly impaired in remembering to do things in the future or prospective memory (PM). The aim of this study was to establish which type of event-based PM is particularly disrupted in aMCI, focal PM, based on spontaneous retrieval, or nonfocal PM that relies on strategic monitoring processes...
April 13, 2017: Neuropsychology
https://www.readbyqxmd.com/read/28405380/robust-associations-between-the-20-item-prosopagnosia-index-and-the-cambridge-face-memory-test-in-the-general-population
#10
Katie L H Gray, Geoffrey Bird, Richard Cook
Developmental prosopagnosia (DP) is a neurodevelopmental condition, characterized by lifelong face recognition deficits. Leading research groups diagnose the condition using complementary computer-based tasks and self-report measures. In an attempt to standardize the reporting of self-report evidence, we recently developed the 20-item prosopagnosia index (PI20), a short questionnaire measure of prosopagnosic traits suitable for screening adult samples for DP. Strong correlations between scores on the PI20 and performance on the Cambridge Face Memory Test (CFMT) appeared to confirm that individuals possess sufficient insight into their face recognition ability to complete a self-report measure of prosopagnosic traits...
March 2017: Royal Society Open Science
https://www.readbyqxmd.com/read/28396645/between-subject-variability-in-the-breaking-continuous-flash-suppression-paradigm-potential-causes-consequences-and-solutions
#11
Surya Gayet, Timo Stein
A recent focus in the field of consciousness research involves investigating the propensity of initially non-conscious visual information to gain access to consciousness. A critical tool for measuring conscious access is the so-called breaking continuous flash suppression paradigm (b-CFS). In this paradigm, a high contrast dynamic pattern is presented to one eye, thereby temporarily suppressing a target stimulus that is presented to the other eye. The time it takes for observers to report (e.g., the location of) the initially suppressed stimulus provides a measure of conscious access...
2017: Frontiers in Psychology
https://www.readbyqxmd.com/read/28386882/working-memory-representations-persist-in-the-face-of-unexpected-task-alterations
#12
Garrett Swan, Brad Wyble, Hui Chen
It is well known that information can be held in memory while performing other tasks concurrently, such as remembering a color or number during a separate visual search task. However, it is not clear what happens to stored information in the face of unexpected tasks, such as the surprise questions that are often used in experiments related to inattentional and change blindness. Does the unpredicted shift in task context cause memory representations to be cleared in anticipation of new information? To answer this question, we ran two experiments where the task unexpectedly switched partway through the experiment with a surprise question...
April 6, 2017: Attention, Perception & Psychophysics
https://www.readbyqxmd.com/read/28386857/reconstructing-the-recent-visual-past-hierarchical-knowledge-based-effects-in-visual-working-memory
#13
Marie Poirier, Daniel Heussen, Silvio Aldrovandi, Lauren Daniel, Saiyara Tasnim, James A Hampton
This paper presents two experiments that examine the influence of multiple levels of knowledge on visual working memory (VWM). Experiment 1 focused on memory for faces. Faces were selected from continua that were constructed by morphing two face photographs in 100 steps; half of the continua morphed a famous face into an unfamiliar one, while the other half used two unfamiliar faces. Participants studied six sequentially presented faces each from a different continuum, and at test they had to locate one of these within its continuum...
April 6, 2017: Psychonomic Bulletin & Review
https://www.readbyqxmd.com/read/28385627/feedback-from-the-heart-emotional-learning-and-memory-is-controlled-by-cardiac-cycle-interoceptive-accuracy-and-personality
#14
Gaby Pfeifer, Sarah N Garfinkel, Cassandra D Gould van Praag, Kuljit Sahota, Sophie Betka, Hugo D Critchley
Feedback processing is critical to trial-and-error learning. Here, we examined whether interoceptive signals concerning the state of cardiovascular arousal influence the processing of reinforcing feedback during the learning of 'emotional' face-name pairs, with subsequent effects on retrieval. Participants (N=29) engaged in a learning task of face-name pairs (fearful, neutral, happy faces). Correct and incorrect learning decisions were reinforced by auditory feedback, which was delivered either at cardiac systole (on the heartbeat, when baroreceptors signal the contraction of the heart to the brain), or at diastole (between heartbeats during baroreceptor quiescence)...
April 3, 2017: Biological Psychology
https://www.readbyqxmd.com/read/28378036/engaging-with-dementia-moral-experiments-in-art-and-friendship
#15
Janelle S Taylor
The box-office as well as critical success of the 2014 major motion picture Still Alice, starring Julianne Moore in the title role and based on the bestselling novel of the same name by the Harvard-trained neuroscientist Lisa Genova (Still Alice. Simon & Schuster, New York, 2009), marked an important moment in public cultural representations of people with dementia. Still Alice tells the story of Alice Howland, an eminent scientist whose increasing memory lapses are eventually diagnosed as early-onset Alzheimer's, and chronicles the transformations in her family relationships as her husband and three children respond to her decline in different ways...
April 4, 2017: Culture, Medicine and Psychiatry
https://www.readbyqxmd.com/read/28372598/semantic-memory-and-depressive-symptoms-in-patients-with-subjective-cognitive-decline-mild-cognitive-impairment-and-alzheimer-s-disease
#16
J Lehrner, G Coutinho, P Mattos, D Moser, M Pflüger, A Gleiss, E Auff, P Dal-Bianco, G Pusswald, E Stögmann
BACKGROUND: Semantic memory may be impaired in clinically recognized states of cognitive impairment. We investigated the relationship between semantic memory and depressive symptoms (DS) in patients with cognitive impairment. METHODS: 323 cognitively healthy controls and 848 patients with subjective cognitive decline (SCD), mild cognitive impairment (MCI), and Alzheimer's disease (AD) dementia were included. Semantic knowledge for famous faces, world capitals, and word vocabulary was investigated...
April 4, 2017: International Psychogeriatrics
https://www.readbyqxmd.com/read/28370532/sleep-dependent-consolidation-of-face-recognition-and-its-relationship-to-rem-sleep-duration-rem-density-and-stage-2-sleep-spindles
#17
Elizaveta Solomonova, Philippe Stenstrom, Emilie Schon, Alexandra Duquette, Simon Dubé, Christian O'Reilly, Tore Nielsen
Face recognition is a highly specialized capability that has implicit and explicit memory components. Studies show that learning tasks with facial components are dependent on rapid eye movement and non-rapid eye movement sleep features, including rapid eye movement sleep density and fast sleep spindles. This study aimed to investigate the relationship between sleep-dependent consolidation of memory for faces and partial rapid eye movement sleep deprivation, rapid eye movement density, and fast and slow non-rapid eye movement sleep spindles...
March 31, 2017: Journal of Sleep Research
https://www.readbyqxmd.com/read/28368135/the-ugliness-in-averageness-effect-tempering-the-warm-glow-of-familiarity
#18
Evan W Carr, David E Huber, Diane Pecher, Rene Zeelenberg, Jamin Halberstadt, Piotr Winkielman
Mere exposure (i.e., stimulus repetition) and blending (i.e., stimulus averaging) are classic ways to increase social preferences, including facial attractiveness. In both effects, increases in preference involve enhanced familiarity. Prominent memory theories assume that familiarity depends on a match between the target and similar items in memory. These theories predict that when individual items are weakly learned, their blends (morphs) should be relatively familiar, and thus liked-a beauty-in-averageness effect (BiA)...
April 3, 2017: Journal of Personality and Social Psychology
https://www.readbyqxmd.com/read/28364428/enhanced-memory-consolidation-via-automatic-sound-stimulation-during-non-rem-sleep
#19
Miika M Leminen, Jussi Virkkala, Emma Saure, Teemu Paajanen, Phyllis C Zee, Giovanni Santostasi, Christer Hublin, Kiti Müller, Tarja Porkka-Heiskanen, Minna Huotilainen, Tiina Paunio
Introduction: Slow-wave sleep (SWS) slow waves and sleep spindle activity have been shown to be crucial for memory consolidation. Recently, memory consolidation has been causally facilitated in human participants via auditory stimuli phase-locked to SWS slow waves. Aims: Here, we aimed to develop a new acoustic stimulus protocol to facilitate learning and to validate it using different memory tasks. Most importantly, the stimulation setup was automated to be applicable for ambulatory home use...
March 1, 2017: Sleep
https://www.readbyqxmd.com/read/28362614/htm-spatial-pooler-with-memristor-crossbar-circuits-for-sparse-biometric-recognition
#20
Alex Pappachen James, Irina Fedorova, Timur Ibrayev, Dhireesha Kudithipudi
Hierarchical Temporal Memory (HTM) is an online machine learning algorithm that emulates the neo-cortex. The development of a scalable on-chip HTM architecture is an open research area. The two core substructures of HTM are spatial pooler and temporal memory. In this work, we propose a new Spatial Pooler circuit design with parallel memristive crossbar arrays for the 2D columns. The proposed design was validated on two different benchmark datasets, face recognition, and speech recognition. The circuits are simulated and analyzed using a practical memristor device model and 0...
March 1, 2017: IEEE Transactions on Biomedical Circuits and Systems
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