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https://www.readbyqxmd.com/read/29146433/a-novel-technique-for-cervical-facet-joint-hyperplasia-spondylotic-radiculopathy-by-laminar-and-lateral-mass-screw-co-fixations
#1
Sun-Ren Sheng, Ke Wang, Majid Nisar, Jiao-Xiang Chen, Ai-Min Wu, Xiang-Yang Wang
OBJECTIVE: To describe the novel technique and report the outcomes of cervical spondylotic radiculopathy caused by facet joint hyperplasia treated with minimally invasive surgery by laminar and lateral mass screw co-fixations. METHOD: In this retrospective study, patients with spondylotic radiculopathy caused by facet joint hyperplasia underwent this technique in our unit between January 2010 and June 2015. Hospital charts, magnetic resonance imaging studies, and follow-up records for all the patients were reviewed...
November 13, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29136257/risk-factors-for-pathological-fracture-and-metastatic-epidural-spinal-cord-compression-in-patients-with-spinal-metastases
#2
Catherine S Hibberd, Gerald M Y Quan
Vertebral pathological fracture and metastatic epidural spinal cord compression (MESCC) due to metastatic cancer inevitably cause pain, neurological deficit, impaired function, and decreased quality of life and are indications for surgery. In such cases, earlier surgical intervention has the potential to prevent permanent neurological deficit and disability and to maintain function and quality of life. Therefore, the aim of this study was to identify and evaluate risk factors for pathological fracture and MESCC in patients with spinal metastases...
November 11, 2017: Orthopedics
https://www.readbyqxmd.com/read/29133003/atlantooccipital-rotatory-dislocation-a-case-report-and-systematic-review
#3
REVIEW
Luis A Robles, Greg M Mundis, Abel Cuevas-Solórzano
BACKGROUND: Atlanto-occipital rotatory dislocation (AORD) has been rarely reported in the literature; for this reason, the clinical-radiological characteristics of this injury are not well described. METHODS: The authors describe the case of a 67 years old male who sustained a cervical spine trauma. He only referred neck pain and was neurologically intact. The CT scan showed a rotatory displacement of the atlanto-occipital joints (AOJs) associated with a widened condylar-C1 interval; in addition, the MRI revealed injuries to the stabilizing ligaments of this area...
November 10, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29132141/shoulder-giant-schwannoma-a-diagnosis-to-be-considered-in-painless-shoulder-masses
#4
Romeu Pinho, Sara Santana, Filipa Farinha, Inês Cunha, Anabela Barcelos, José Brenha
Tumours formed from peripheral nerve sheaths are rare in the shoulder. We present the case of a 80-year-old female referred to an orthopaedic surgery clinic because of a large painless mass of the right shoulder, with one year of evolution. There was no history of trauma, involvement of any other joint or systemic complaints. Given the clinical and imagiological suspicion of a giant synovial cyst, the patient underwent complete surgical resection of the mass, which took place without any complications or functional impairment...
November 5, 2017: Acta Reumatológica Portuguesa
https://www.readbyqxmd.com/read/29131326/magnesium-in-migraine-prophylaxis-is-there-an-evidence-based-rationale-a-systematic-review
#5
REVIEW
Alexander von Luckner, Franz Riederer
OBJECTIVE: The primary objective was to systematically evaluate the existing evidence base on magnesium in migraine prophylaxis. METHODS: The search for clinical trials published from 1990 to 2016 was separately conducted by AvL and FR using standard search terms as well as MeSh terms on PubMed and EMBASE. Randomized, double-blind, placebo-controlled trials investigating prophylactic magnesium administration in migraineurs aged 18-65 were considered eligible. In a mutual effort, the studies found were sorted and analyzed under consideration of the guidelines for controlled trials for drugs in migraine by the International Headache Society and using predefined eligibility criteria...
November 13, 2017: Headache
https://www.readbyqxmd.com/read/29130654/-classification-and-treatment-of-sacroiliac-joint-dislocation
#6
Zhen Tan, Zhong Huang, Liang Li, Wei-Kun Meng, Lei Liu, Hui Zhang, Guang-Lin Wang, Fu-Guo Huang
OBJECTIVE: To develop a renewed classification and treatment regimen for sacroiliac joint dislocation. METHODS: According to the direction of dislocation of sacroiliac joint,combined iliac,sacral fractures,and fracture morphology,sacroiliac joint dislocation was classified into 4 types. Type Ⅰ (sacroiliac anterior dislocation): main fracture fragments of posterior iliac wing dislocated in front of sacroiliac joint. Type Ⅱ (sacroiliac posterior dislocation): main fracture fragments of posterior iliac wing dislocated in posterior of sacroiliac joint...
September 2017: Sichuan da Xue Xue Bao. Yi Xue Ban, Journal of Sichuan University. Medical Science Edition
https://www.readbyqxmd.com/read/29128308/oxidative-stress-and-dna-damage-after-cerebral-ischemia-potential-therapeutic-targets-to-preserve-the-genome-and-improve-stroke-recovery
#7
REVIEW
Peiying Li, R Anne Stetler, Rehana K Leak, Yejie Shi, Yan Li, Weifeng Yu, Michael V L Bennett, Jun Chen
The past two decades have witnessed remarkable advances in oxidative stress research, particularly in the context of ischemic brain injury. Oxidative stress in ischemic tissues compromises the integrity of the genome, resulting in DNA lesions, cell death in neurons, glial cells, and vascular cells, and impairments in neurological recovery after stroke. As DNA is particularly vulnerable to oxidative attack, cells have evolved the ability to induce multiple DNA repair mechanisms, including base excision repair (BER), nucleotide excision repair (NER) and non-homogenous endpoint jointing (NHEJ)...
November 8, 2017: Neuropharmacology
https://www.readbyqxmd.com/read/29118693/design-of-a-soft-robotic-elbow-sleeve-with-passive-and-intent-controlled-actuation
#8
Tze Hui Koh, Nicholas Cheng, Hong Kai Yap, Chen-Hua Yeow
The provision of continuous passive, and intent-based assisted movements for neuromuscular training can be incorporated into a robotic elbow sleeve. The objective of this study is to propose the design and test the functionality of a soft robotic elbow sleeve in assisting flexion and extension of the elbow, both passively and using intent-based motion reinforcement. First, the elbow sleeve was developed, using elastomeric and fabric-based pneumatic actuators, which are soft and lightweight, in order to address issues of non-portability and poor alignment with joints that conventional robotic rehabilitation devices are faced with...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/29116817/perceptions-of-a-psychoeducation-program-for-caregivers-of-persons-with-dementia-at-end-of-life-a-qualitative-study
#9
Pamela Durepos, Sharon Kaasalainen, Sandra Carroll, Alexandra Papaioannou
OBJECTIVES: Caregivers (CG) of persons with dementia have described positive and challenging experiences related to caring for a person with a neurological disease. This study explored perceived benefits and challenges of a unique psychoeducation program provided at end of life (EOL) jointly attended by current and bereaved CGs of persons with dementia, residing in a hospital Specialized Care Unit. METHOD: Semi-structured interviews were held with sixteen participants and analyzed with content analysis...
November 8, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/29110219/reduction-and-fixation-of-displaced-u-shaped-sacral-fractures-using-lumbopelvic-fixation-technical-recommendations
#10
Stefan Piltz, Bianka Rubenbauer, Wolfgang Böcker, Heiko Trentzsch
PURPOSE: U-shaped sacral fractures are extremely rare injuries that usually occur as a result of falls from considerable heights. Almost all treatment methods described to date aim solely at stabilizing the fracture but do not contribute to supporting the reduction of such fractures. Using existing implants the purpose of this study is to present a surgical technique that facilitates both the reduction and the stabilization of these injuries. The presented technique was evaluated in a series of three cases...
November 6, 2017: European Spine Journal
https://www.readbyqxmd.com/read/29102512/ninety-day-morbidity-and-mortality-in-risk-screened-and-optimized-patients-undergoing-two-team-fast-track-simultaneous-bilateral-tka-compared-with-unilateral-tka-a-prospective-study
#11
Vikas Kulshrestha, Santhosh Kumar, Barun Datta, V K Sinha, Gaurav Mittal
BACKGROUND: Simultaneous bilateral total knee arthroplasty (SBTKA) offers significant socioeconomic benefits. However, retrospective studies and public health data show increased mortality and morbidity rates in patients undergoing SBTKA compared with those undergoing unilateral TKA (UTKA), and there have been recommendations against the use of SBTKA. High-volume centers, which feature careful patient selection and fast-tracked surgery, continue to perform SBTKA and have published their results in favor of the procedure...
October 10, 2017: Journal of Arthroplasty
https://www.readbyqxmd.com/read/29099873/assessing-zika-virus-replication-and-the-development-of-zika-specific-antibodies-after-a-mid-gestation-viral-challenge-in-guinea-pigs
#12
Craig J Bierle, Claudia Fernández-Alarcón, Nelmary Hernandez-Alvarado, Jason C Zabeli, Bradley C Janus, Dira S Putri, Mark R Schleiss
Primary Zika virus (ZIKV) infections that occur during pregnancy can cause spontaneous abortion and profoundly disrupt fetal development. While the full range of developmental abnormalities associated with congenital Zika syndrome is not yet known, severe cases of the syndrome can present with microcephaly, extensive neurologic and ocular damage, and pronounced joint malformations. Animal models that accurately recapitulate congenital Zika syndrome are urgently needed for vaccine development and for the study of ZIKV pathogenesis...
2017: PloS One
https://www.readbyqxmd.com/read/29097955/thoracic-schwannoma-in-an-adult-male-presenting-with-thoracic-pain-a-case-report
#13
Andrew M Rodgers, Kim B Khauv
Objective: The purpose of this case report was to describe a patient presenting with back pain subsequently diagnosed with thoracic schwannoma. Clinical Features: A 45-year-old male presented to a chiropractic practice with mid-back, low back, and sacroiliac pain. Orthopedic examination revealed joint dysfunction in the thoracic-sacroiliac region with normal findings on neurologic examination. An initial diagnosis of thoracic spinal pain and sacroiliac sprain and strain was made...
September 2017: Journal of Chiropractic Medicine
https://www.readbyqxmd.com/read/29089196/immediate-effect-of-a-functional-wrist-orthosis-for-children-with-cerebral-palsy-or-brain-injury-a-randomized-controlled-trial
#14
Michelle Jackman, Iona Novak, Natasha Lannin, Claire Galea
STUDY DESIGN: Two-group randomized controlled trial. INTRODUCTION: Upper limb orthoses worn during functional tasks are commonly used in pediatric neurologic rehabilitation, despite a paucity of high-level evidence. PURPOSE OF THE STUDY: The purpose of this study was to investigate if a customized functional wrist orthosis, when placed on the limb, leads to an immediate improvement in hand function for children with cerebral palsy or brain injury...
October 28, 2017: Journal of Hand Therapy: Official Journal of the American Society of Hand Therapists
https://www.readbyqxmd.com/read/29082779/role-of-extra-articular-tibiotalocalcaneal-arthrodesis-and-posterior-approach-in-highly-complex-cases
#15
Sergio Eckholt, Ruben Garcia-Elvira, Nicolás Fontecilla, Alvaro Fernandez-Reinales, Daniel Poggio
BACKGROUND: Tibiotalocalcaneal (TTC) arthrodesis is a procedure commonly used as salvage surgery for various pathologic processes that compromise the ankle and subtalar joints. It is a reasonably standardized procedure when performed as a primary surgery in advanced stages of TTC arthritis. For such cases, there are several alternative approaches, fixation materials, and bone substitutes that can be used. Most represent valid options with similar results in the literature. However, in highly complex cases requiring TTC arthrodesis, the options for the approach and fixation material can be limited...
October 1, 2017: Foot & Ankle International
https://www.readbyqxmd.com/read/29081394/a-case-of-asymptomatic-occipital-condyle-fracture-with-incomplete-occipito-cervical-dislocation-how-did-it-happen
#16
P Anania, P Fiaschi, P F Sbaffi, G L Zona
Atlanto-occipital dislocation (AODs) is a lesion rarely observed in a trauma center, due to high mortality in the preclinical phase. The number of AODs survivors is increasing thanks to the improvement in prehospital resuscitation. Our goal is to describe a case of incomplete atlanto-occipital dislocation presented without any neurological, cardio-respiratory, or metabolic problems, which remained constant even after surgical treatment. Our purpose is also to discuss treatment approaches to minimize subsequent neurological deficits...
October 25, 2017: World Neurosurgery
https://www.readbyqxmd.com/read/29073937/tumoral-calcinosis-in-the-cervical-spine-a-case-report-and-review-of-the-literature
#17
Rui Guo, Tatsuya Kurata, Tetsushi Kondo, Takao Imanishi, Tetsutaro Mizuno, Toshihiko Sakakibara, Yuichi Kasai
BACKGROUND: Tumoral calcinosis is rarely located in spine. A 55-year-old Japanese woman with cervical tumoral calcinosis is presented, along with a review of the literature relating to tumoral calcinosis in the spine. We discussed the etiology, diagnosis, and management of this condition. CASE PRESENTATION: We report a case of a patient with cervical tumoral calcinosis with end-stage renal disease. A computed tomography scan showed a lobulated, calcified mass around the right facet joint at the fourth-fifth cervical spine and calcifications were also observed in the right intervertebral foramens at fourth-fifth cervical spine and fifth-sixth cervical spine levels and the anterior wall of the spinal canal...
October 27, 2017: Journal of Medical Case Reports
https://www.readbyqxmd.com/read/29069985/neural-autoantibodies-in-patients-with-neurological-symptoms-and-histories-of-chemical-mold-exposures
#18
Mohamed Bahie Abou-Donia, Allan Lieberman, Luke Curtis
A number of studies have linked exposures to industrial and household chemicals and biological toxins to increased risk of autoimmunity in general and elevated levels of autoantibodies to neural antigens specifically. Elevated neural autoantibodies are biomarkers for many diseases such as multiple sclerosis and Parkinson's disease. Our study reports levels of six types of neural autoantibodies in a group of 24 toxicant-exposed patients. The patients were exposed to a variety of toxicants including contaminated drinking water (four patients), building water/mold damage (eight patients), pesticides (four patients), and other assorted toxic chemicals (eight patients)...
January 1, 2017: Toxicology and Industrial Health
https://www.readbyqxmd.com/read/29068880/quantitative-magnetization-transfer-mri-measurements-of-the-anterior-spinal-cord-region-are-associated-with-clinical-outcomes-in-cervical-spondylotic-myelopathy
#19
Michael Brendan Cloney, Zachary A Smith, Kenneth A Weber, Todd B Parrish
STUDY DESIGN: case-control. OBJECTIVE: To understand the role of magnetization transfer ratio in identifying patients with clinically significant myelopathy and disability. SUMMARY OF BACKGROUND DATA: Magnetization transfer ratio (MTR) is a quantitative measure that correlates with myelin loss and neural tissue destruction in a variety of neurological diseases. However, the usefulness of MTR in patients with cervical spondylotic myelopathy (CSM) has not been examined...
October 24, 2017: Spine
https://www.readbyqxmd.com/read/29059370/faster-family-wise-error-control-for-neuroimaging-with-a-parametric-bootstrap
#20
Simon N Vandekar, Theodore D Satterthwaite, Adon Rosen, Rastko Ciric, David R Roalf, Kosha Ruparel, Ruben C Gur, Raquel E Gur, Russell T Shinohara
In neuroimaging, hundreds to hundreds of thousands of tests are performed across a set of brain regions or all locations in an image. Recent studies have shown that the most common family-wise error (FWE) controlling procedures in imaging, which rely on classical mathematical inequalities or Gaussian random field theory, yield FWE rates (FWER) that are far from the nominal level. Depending on the approach used, the FWER can be exceedingly small or grossly inflated. Given the widespread use of neuroimaging as a tool for understanding neurological and psychiatric disorders, it is imperative that reliable multiple testing procedures are available...
October 20, 2017: Biostatistics
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