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https://www.readbyqxmd.com/read/28647204/return-to-competition-after-an-achilles-tendon-rupture-using-both-on-and-off-the-field-load-monitoring-as-guidance-a-case-report-of-a-top-level-soccer-player
#1
Maurizio Fanchini, Franco M Impellizzeri, Karin Grävare Silbernagel, Franco Combi, Franco Benazzo, Mario Bizzini
OBJECTIVES: To describe the Return to competition after Achilles Tendon rupture (ATR) in an elite soccer player. DESIGN: Case report. SETTING: Return to sport (RTS) of a professional soccer player who suffered an ATR during a match. The RTS phase started 15 weeks after surgery and specific on-field activities were gradually introduced. Criteria used to monitor the transition through the different phases were strength and endurance of the calf muscle and ability to sustain specific on-field training loads (TL) monitored with Global Positioning System and heart-rate system...
April 29, 2017: Physical Therapy in Sport
https://www.readbyqxmd.com/read/28646958/new-tools-for-malaria-control-using-them-wisely
#2
Brian Greenwood
The incidence of malaria in sub-Saharan Africa is falling and in many countries on the continent the pattern of malaria infection within the country is becoming more heterogeneous. National malaria control programmes need to take this into account and the 'one size fits all' approach to malaria control may no longer be appropriate, with individual approaches being needed in different parts of a country. This applies particularly to decisions on the introduction of new control tools. Recent experience with Seasonal Malaria Chemoprevention and with the RTS,S/AS01 malaria vaccine provides examples of interventions which need to be deployed on a restricted rather than a national basis, taking account of differences in climate and the intensity of malaria infection between regions within a country...
June 2017: Journal of Infection
https://www.readbyqxmd.com/read/28644677/young-athletes-after-anterior-cruciate-ligament-reconstruction-with-single-leg-landing-asymmetries-at-the-time-of-return-to-sport-demonstrate-decreased-knee-function-2-years-later
#3
Matthew P Ithurburn, Mark V Paterno, Kevin R Ford, Timothy E Hewett, Laura C Schmitt
BACKGROUND: Previous work shows that young athletes after anterior cruciate ligament reconstruction (ACLR) demonstrate single-leg (SL) landing movement asymmetries at the time of return to sport (RTS); however, the effect of movement asymmetries on longitudinal knee-related function after ACLR has not been examined. Hypothesis/Purpose: The purpose of this study was to examine the effect of SL drop-landing movement symmetry at the time of RTS on knee-related function 2 years later in young athletes after ACLR...
June 1, 2017: American Journal of Sports Medicine
https://www.readbyqxmd.com/read/28643517/a-novel-strategy-for-comprehensive-profiling-and-identification-of-acidic-glycosphingolipids-using-ultra-high-performance-liquid-chromatography-coupled-with-quadrupole-time-of-flight-mass-spectrometry
#4
Ting Hu, Zhixin Jia, Jinlan Zhang
Acidic glycosphingolipids (AGSLs), which mainly consist of ganglioside and sulfatide moieties, are highly concentrated in the central nervous system. Comprehensive profiling of AGSLs has historically been challenging because of their high complexity and the lack of standards. In this paper, a novel strategy was developed to comprehensively profile AGSLs using ultra-high-performance liquid chromatography-quadrupole time of flight mass spectrometry (UPLC-Q-TOF-MS). Ganglioside isomers with different glycan chains such as GD1a/ GD1b were completely separated on a C18 column for the first time to our knowledge, facilitated by the addition of formic acid in the mobile phase...
June 23, 2017: Analytical Chemistry
https://www.readbyqxmd.com/read/28639799/aging-and-confidence-judgments-in-item-recognition
#5
Chelsea Voskuilen, Roger Ratcliff, Gail McKoon
We examined the effects of aging on performance in an item-recognition experiment with confidence judgments. A model for confidence judgments and response time (RTs; Ratcliff & Starns, 2013) was used to fit a large amount of data from a new sample of older adults and a previously reported sample of younger adults. This model of confidence judgments allows us to distinguish between changes evidence from memory and changes in decision-related components and it accounts for both RT distributions and response proportions...
June 22, 2017: Journal of Experimental Psychology. Learning, Memory, and Cognition
https://www.readbyqxmd.com/read/28637583/the-revised-trauma-score-plus-serum-albumin-level-improves-the-prediction-of-mortality-in-trauma-patients
#6
Seong Chun Kim, Dong Hoon Kim, Tae Yun Kim, Changwoo Kang, Soo Hoon Lee, Jin Hee Jeong, Yong Joo Park, Sang Bong Lee, Daesung Lim
INTRODUCTION: The Revised Trauma Score (RTS) is used worldwide in prehospital practice and in the emergency department (ED) settings to triage trauma patients. The main purpose of this study was to evaluate the value of the RTS plus serum albumin (RTS-A) and to compare it with other existing trauma scores as well as to compare the predictive performance of the Trauma and Injury Severity Score with the RTS-A (TRISS-A) with the original TRISS. METHODS: This was a single center, trauma registry based observational cohort study...
June 15, 2017: American Journal of Emergency Medicine
https://www.readbyqxmd.com/read/28635139/improving-precision-of-ability-estimation-getting-more-from-response-times
#7
Maria Bolsinova, Jesper Tijmstra
By considering information about response time (RT) in addition to response accuracy (RA), joint models for RA and RT such as the hierarchical model (van der Linden, 2007) can improve the precision with which ability is estimated over models that only consider RA. The hierarchical model, however, assumes that only the person's speed is informative of ability. This assumption of conditional independence between RT and ability given speed may be violated in practice, and ignores collateral information about ability that may be present in the residual RTs...
June 21, 2017: British Journal of Mathematical and Statistical Psychology
https://www.readbyqxmd.com/read/28632746/body-part-compatibility-effects-are-modulated-by-the-tendency-for-women-to-experience-negative-social-comparative-emotions-and-the-body-type-of-the-model
#8
Eva Pila, Kimberely Jovanov, Timothy N Welsh, Catherine M Sabiston
Although exposure to physique-salient media images of women's bodies has been consistently linked with negative psychological consequences, little is known about the cognitive processes that lead to these negative effects. The present study employed a novel adaptation of a computerized response time (RT) task to (i) assess implicit cognitive processing when exposed to the body of another individual, and (ii) examine individual differences in social comparative emotions that may influence the cognitive processing of human bodies...
2017: PloS One
https://www.readbyqxmd.com/read/28632522/relationship-of-reaction-time-to-perception-of-a-stimulus-and-volitionally-delayed-response
#9
Kimford J Meador, Alan Boyd, David W Loring
BACKGROUND AND OBJECTIVE: Initiation of response in a simple reaction time (RT) task may precede conscious perception of the stimulus. Since volitionally delayed responses may require conscious perception of the stimulus before response initiation, it has been hypothesized that volitionally delayed responses will markedly delay RT. METHODS: We conducted two experiments with separate groups of healthy volunteers (n=16; n=13) who performed computerized simple and choice RT tasks...
June 2017: Cognitive and Behavioral Neurology: Official Journal of the Society for Behavioral and Cognitive Neurology
https://www.readbyqxmd.com/read/28625430/sensorimotor-and-executive-function-slowing-in-anesthesiology-residents-after-overnight-shifts
#10
George W Williams, Bairavi Shankar, Eliana M Klier, Alice Z Chuang, Salma El Marjiya-Villarreal, Omonele O Nwokolo, Aanchal Sharma, Anne B Sereno
STUDY OBJECTIVE: Medical residents working overnight call shifts experience sleep deprivation and circadian clock disruption. This leads to deficits in sensorimotor function and increases in workplace accidents. Using quick tablet-based tasks, we investigate whether measureable executive function differences exist following a single overnight call versus routine shift, and whether factors like stress, rest and caffeine affect these measures. DESIGN: A prospective, observational, longitudinal, comparison study was conducted...
August 2017: Journal of Clinical Anesthesia
https://www.readbyqxmd.com/read/28624854/superior-return-to-sports-rate-after-patellar-tendon-autograft-over-patellar-tendon-allograft-in-revision-anterior-cruciate-ligament-reconstruction
#11
Michèle N J Keizer, Roy A G Hoogeslag, Jos J A M van Raay, Egbert Otten, Reinoud W Brouwer
PURPOSE: After revision anterior cruciate ligament reconstruction (ACLR), the rate of return to the pre-injury type of sport (RTS type) is low and graft choice might be an important factor. The aim of this study was to determine whether there is a difference in outcome after revision ACLR using a patellar tendon allograft compared to an ipsilateral patellar tendon autograft. It was hypothesized that the rate of RTS type using an ipsilateral patellar tendon autograft will be superior to using patellar tendon allograft...
June 17, 2017: Knee Surgery, Sports Traumatology, Arthroscopy: Official Journal of the ESSKA
https://www.readbyqxmd.com/read/28620388/trichinella-spiralis-calreticulin-binds-human-complement-c1q-as-an-immune-evasion-strategy
#12
Limei Zhao, Shuai Shao, Yi Chen, Ximeng Sun, Ran Sun, Jingjing Huang, Bin Zhan, Xinping Zhu
As a multicellular parasitic nematode, Trichinella spiralis regulates host immune responses by producing a variety of immunomodulatory molecules to escape from host immune attack, but the mechanisms underlying the immune evasion are not well understood. Here, we identified that T. spiralis calreticulin (Ts-CRT), a Ca(2+)-binding protein, facilitated T. spiralis immune evasion by interacting with the first component of human classical complement pathway, C1q. In the present study, Ts-CRT was found to be expressed on the surface of different developmental stages of T...
2017: Frontiers in Immunology
https://www.readbyqxmd.com/read/28620006/cancer-surveillance-in-gorlin-syndrome-and-rhabdoid-tumor-predisposition-syndrome
#13
REVIEW
William D Foulkes, Junne Kamihara, D Gareth R Evans, Laurence Brugières, Franck Bourdeaut, Jan J Molenaar, Michael F Walsh, Garrett M Brodeur, Lisa Diller
Gorlin syndrome and rhabdoid tumor predisposition syndrome (RTPS) are autosomal dominant syndromes associated with an increased risk of childhood-onset brain tumors. Individuals with Gorlin syndrome can manifest a wide range of phenotypic abnormalities, with about 5% of family members developing medulloblastoma, usually occurring in the first 3 years of life. Gorlin syndrome is associated with germline mutations in components of the Sonic Hedgehog pathway, including Patched1 (PTCH1) and Suppressor of fused (SUFU)SUFU mutation carriers appear to have an especially high risk of early-onset medulloblastoma...
June 15, 2017: Clinical Cancer Research: An Official Journal of the American Association for Cancer Research
https://www.readbyqxmd.com/read/28614399/the-effects-of-high-frequency-rtms-over-the-left-dlpfc-on-cognitive-control-in-young-healthy-participants
#14
Yanmin Li, Lin Wang, Meng Jia, Jihong Guo, Huijun Wang, Mingwei Wang
A large body of evidence suggests that repetitive transcranial magnetic stimulation (rTMS) is clinically effective in treating neuropsychiatric disorders and multiple sessions are commonly used. However, it is unknown whether multiple sessions of rTMS improve cognitive control, which is a function of the neural circuitry of the left dorsolateral prefrontal cortex (DLPFC)-cingulate cortex in healthy individuals. In addition, it is still unclear which stages of neural processing are altered by rTMS. In this study, we investigated the effects of high-frequency rTMS on cognitive control and explored the time course changes of cognitive processing after rTMS using event-related potentials (ERPs)...
2017: PloS One
https://www.readbyqxmd.com/read/28613894/individual-defects-in-inas-ingaassb-gasb-nanowire-tunnel-field-effect-transistors-operating-below-60-mv-decade
#15
Elvedin Memisevic, Markus Hellenbrand, Erik Lind, Axel R Persson, Saurabh Sant, Andreas Schenk, Johannes Svensson, Lars-Erik Wernersson, Lars Reine Wallenberg
Tunneling Field-Effect Transistors (TunnelFET), a leading steep-slope transistor candidate, is still plagued by defect response and there is a large discrepancy between measured and simulated device performance. In this work, highly scaled InAs-InxGa1-xAsySb1-y-GaSb vertical nanowire TunnelFET with ability to operate well below 60 mV/decade at technically relevant currents are fabricated and characterized. The structure, composition, and strain is characterized using transmission electron microscopy with emphasis on the heterojunction...
June 14, 2017: Nano Letters
https://www.readbyqxmd.com/read/28604460/intention-to-treat-analysis-of-radical-trachelectomy-for-early-stage-cervical-cancer-with-special-reference-to-oncologic-failures-single-institutional-experience-in-hungary
#16
Robert Póka, Szabolcs Molnár, Péter Daragó, János Lukács, Rudolf Lampé, Zoárd Krasznai, Zoltán Hernádi
OBJECTIVE: The aim of our study was to evaluate clinical and pathological data in order to draw eligibility criteria for oncologically sufficient radical trachelectomy (RT) in early-stage cervical cancer. Reviewing all cases of attempted RT performed at our unit, we focused attention on prognostic indicators of the need for additional oncologic treatment following RT. The analysis was extended by extensive literature review to include previously published cases of oncologic failures. METHODS: The authors retrospectively analyzed data of patients who underwent RT at the Department of Obstetrics and Gynecology, University of Debrecen...
June 10, 2017: International Journal of Gynecological Cancer
https://www.readbyqxmd.com/read/28604122/blood-stage-malaria-vaccines-post-genome-strategies-for-the-identification-of-novel-vaccine-candidates
#17
Edward H Ntege, Eizo Takashima, Masayuki Morita, Hikaru Nagaoka, Tomoko Ishino, Takafumi Tsuboi
An efficacious malaria vaccine is necessary to advance the current control measures towards malaria elimination. To-date, only RTS,S/AS01, a leading pre-erythrocytic stage vaccine completed phase 3 trials, but with an efficacy of 28-36% in children, and 18-26% in infants, that waned over time. Blood-stage malaria vaccines protect against disease, and are considered effective targets for the logical design of next generation vaccines to improve the RTS,S field efficacy. Therefore, novel blood-stage vaccine candidate discovery efforts are critical, albeit with several challenges including, high polymorphisms in vaccine antigens, poor understanding of targets of naturally protective immunity, and difficulties in the expression of high AT-rich plasmodial proteins...
June 19, 2017: Expert Review of Vaccines
https://www.readbyqxmd.com/read/28604042/caution-follows-fear-evidence-from-hierarchical-drift-diffusion-modelling
#18
Jason Tipples
Fearful expressions are thought to warn of potential threat (Davis et al., 2011; Whalen, 1998) and therefore, 1 response to seeing fear might be to react cautiously. Although previous studies have tested for an effect of seeing fear on visual perception, they have not tested for increased decision making caution. Here, I applied hierarchical drift diffusion modeling (Vandekerckhove, Tuerlinckx, & Lee, 2011; Wiecki, Sofer, & Frank, 2013) to the results of 4 experiments designed to test the idea that seeing facial expressions both impairs visual perception (Bocanegra & Zeelenberg, 2009) and leads to changes in decision making caution...
June 12, 2017: Emotion
https://www.readbyqxmd.com/read/28604027/load-theory-behind-the-wheel-perceptual-cognitive-load-effects
#19
Gillian Murphy, Ciara M Greene
Perceptual Load Theory has been proposed as a resolution to the longstanding early versus late selection debate in cognitive psychology. There is much evidence in support of Load Theory but very few applied studies, despite the potential for the model to shed light on everyday attention and distraction. Using a driving simulator, the effect of perceptual and cognitive load on drivers' visual search was assessed. The findings were largely in line with Load Theory, with reduced distractor processing under high perceptual load, but increased distractor processing under high cognitive load...
June 12, 2017: Canadian Journal of Experimental Psychology, Revue Canadienne de Psychologie Expérimentale
https://www.readbyqxmd.com/read/28600717/reading-and-lexical-decision-tasks-generate-different-patterns-of-individual-variability-as-a-function-of-condition-difficulty
#20
Pierluigi Zoccolotti, Maria De Luca, Gloria Di Filippo, Chiara Valeria Marinelli, Donatella Spinelli
We reanalyzed previous experiments based on lexical-decision and reading-aloud tasks in children with dyslexia and control children and tested the prediction of the difference engine model (DEM) that mean condition reaction times (RTs) and standard deviations (SDs) would be linearly related (Myerson et al., 2003). Then we evaluated the slope and the intercept with the x-axis of these linear functions in comparison with previously reported values (i.e., slope of about 0.30 and intercept of about 300 ms). In the case of lexical decision, the parameters were close to these values; by contrast, in the case of reading aloud, a much steeper slope (0...
June 9, 2017: Psychonomic Bulletin & Review
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