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Toxocara canis

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https://www.readbyqxmd.com/read/29351076/parasites-in-stray-dogs-from-italy-prevalence-risk-factors-and-management-concerns
#1
Claudio De Liberato, Federica Berrilli, Livio Odorizi, Roberto Scarcella, Marco Barni, Cristina Amoruso, Alessia Scarito, Margherita Montalbano Di Filippo, Andrea Carvelli, Francesca Iacoponi, Paola Scaramozzino
Parasites are among the most common pathogens recorded in dogs. High prevalence rates are usually reported in stray and shelter dogs, as these animals are less likely to be tested and treated. In this study a survey was carried out on intestinal and lung parasites of stray dogs at the moment of the admission in a shelter in Central Italy. In the period June 2014-June 2015, 262 individual faecal samples were examined. Twelve parasitic taxa were detected. Helminths were more prevalent than protozoa (61.8% and 25...
March 26, 2018: Acta Parasitologica
https://www.readbyqxmd.com/read/29274214/helminth-infections-in-faecal-samples-of-apennine-wolf-canis-lupus-italicus-and-marsican-brown-bear-ursus-arctos-marsicanus-in-two-protected-national-parks-of-central-italy
#2
Barbara Paoletti, Raffaella Iorio, Donato Traversa, Cristina E Di Francesco, Leonardo Gentile, Simone Angelucci, Cristina Amicucci, Roberto Bartolini, Marianna Marangi, Angela Di Cesare
This article reports the results of a copromicroscopic and molecular investigation carried out on faecal samples of wolves (n=37) and brown bears (n=80) collected in two protected national parks of central Italy (Abruzzo Region). Twenty-three (62.2%) samples from wolves were positive for parasite eggs. Eight (34.78%) samples scored positive for single infections, i.e. E. aerophilus (21.74%), Ancylostoma/Uncinaria (4.34%), Trichuris vulpis (4.34%), T. canis (4.34%). Polyspecific infections were found in 15 samples (65...
2017: Annals of Parasitology
https://www.readbyqxmd.com/read/29273062/enhanced-expressions-of-neurodegeneration-associated-factors-ups-impairment-and-excess-a%C3%AE-accumulation-in-the-hippocampus-of-mice-with-persistent-cerebral-toxocariasis
#3
Chia-Mei Chou, Yueh-Lun Lee, Chien-Wei Liao, Ying-Chieh Huang, Chia-Kwung Fan
BACKGROUND: Toxocariasis is a worldwide zoonotic parasitic disease mainly caused by Toxocara canis. Humans can be infected by accidental ingestion of T. canis embryonated ovum-contaminated food, water, or encapsulated larvae in paratenic hosts' viscera or meat. Since humans and mice are paratenic hosts of T. canis, the wandering larvae might cause mechanical tissue damage and excretory-secretory antigens may trigger inflammatory injuries to local organs. Long-term residence of T. canis larvae in a paratenic host's brain may cause cerebral toxocariasis (CT) that contributes to cerebral damage, neuroinflammation and neuropsychiatric disorders in mice and clinical patients...
December 22, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29243027/lactobacillus-rhamnosus-reduces-parasite-load-on-toxocara-canis-experimental-infection-in-mice-but-has-no-effect-on-the-parasite-in-vitro
#4
Débora Liliane Walcher, Luis Augusto Xavier Cruz, Paula de Lima Telmo, Lourdes Helena Rodrigues Martins, Luciana Farias da Costa de Avila, Maria Elisabeth Aires Berne, Carlos James Scaini
Human toxocariasis is a neglected global parasitic zoonosis. The efficacy of drug treatment for this disease has been hindered by the biological complexity of the main etiological agent, the nematode Toxocara canis. Experimental studies have shown the potential of probiotics to promote a reduction in the parasite load of T. canis larvae. This study aimed to evaluate the effect of probiotic Lactobacillus rhamnosus ATCC 7469 on the parasite load of BALB/c mice with acute toxocariasis and evaluate the direct effect of this probiotic on T...
December 14, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29221930/in-vitro-effect-of-chrysosporium-indicum-and-chrysosporium-keratinophylum-on-toxocara-canis-eggs
#5
María V Bojanich, Juan A Basualdo, Gustavo Giusiano
The degree of antagonism exercised by fungi on geohelminth development varies according to the morphological alterations caused by different fungal species. Saprophytic fungi may exert ovicidal or ovistatic effects. The aim of this study was to apply scanning electron microscopy (SEM) to observe the action of two soil saprophytic species of Chrysosporium (C. indicum and C. keratinophylum) on Toxocara canis eggs. The fungal strains to be tested were incubated for 28 days at 28°C in 2% water agar with a suspension of unembryonated T...
December 5, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29173542/regression-models-to-assess-the-risk-factors-of-canine-gastrointestinal-parasitism
#6
I Symeonidou, A Ι Gelasakis, K V Arsenopoulos, R Schaper, E Papadopoulos
Gastrointestinal parasites, protozoa and helminths, remain a common important finding in dogs presented to veterinary medical practices. Moreover, dogs may play an active role in the transmission of enteric parasites to humans, given their cohabitation, making canine gastrointestinal parasitism an issue of major concern for public health. To get an overview of the current state of canine gastrointestinal parasites' prevalence in Greece, a total of 1036 faecal samples were collected from dogs either presented in veterinary clinics or in animal shelters...
December 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29160521/migration-pattern-of-toxocara-canis-larvae-in-experimentally-infected-male-and-female-rattus-norvegicus
#7
Sergio Vieira Dos Santos, Felipe Henrique Yazawa Santos, Susana Angelica Zevallos Lescano, Daniel Maurício Dos Santos, Érico da Silva Tiago, Gabriela Rodrigues E Fonseca, Manoel Carlos Sampaio de Almeida Ribeiro, Pedro Paulo Chieffi
No abstract text is available yet for this article.
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
https://www.readbyqxmd.com/read/29150700/prevalence-of-intestinal-parasites-in-companion-dogs-with-diarrhea-in-beijing-china-and-genetic-characteristics-of-giardia-and-cryptosporidium-species
#8
Zhongjia Yu, Yang Ruan, Mengjie Zhou, Siyuan Chen, Yinxin Zhang, Liya Wang, Guan Zhu, Yonglan Yu
Companion animals including dogs are one of the important components in One Health. Parasites may cause not only diseases in pet animals but also many zoonotic diseases infecting humans. In this study, we performed a survey of intestinal parasites in fecal specimens (n = 485) collected from outpatient pet dogs with diarrhea in Beijing, China, for the entire year of 2015 by microscopic examination (all parasites) and SSU rRNA-based nested PCR detection (Giardia and Cryptosporidium). We observed a total of 124 (25...
November 18, 2017: Parasitology Research
https://www.readbyqxmd.com/read/29143662/heat-treatment-and-false-positive-heartworm-antigen-testing-in-ex-vivo-parasites-and-dogs-naturally-infected-by-dirofilaria-repens-and-angiostrongylus-vasorum
#9
Luigi Venco, Simone Manzocchi, Marco Genchi, Laura H Kramer
BACKGROUND: Heartworm antigen testing is considered sensitive and specific. Currently available tests are reported as detecting a glycoprotein found predominantly in the reproductive tract of the female worm and can reach specificity close to 100%. Main concerns regard sensitivity in the case of light infections, the presence of immature females or cases of all-male infections. Research and development have been aimed at increasing sensitivity. Recently, heat treatment of serum prior to antigen testing has been shown to result in an increase in positive antigen test results, presumably due to disruption of natural antigen-antibody complexes...
November 9, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29141740/a-lateral-flow-rapid-test-for-human-toxocariasis-developed-using-three-toxocara-canis-recombinant-antigens
#10
Muhammad Hafiznur Yunus, Siti Naqiuyah Tan Farrizam, Izzati Zahidah Abdul Karim, Rahmah Noordin
Laboratory diagnosis of toxocariasis is still a challenge especially in developing endemic countries with polyparasitism. In this study, three Toxocara canis recombinant antigens, rTES-26, rTES-30, and rTES-120, were expressed and used to prepare lateral flow immunoglobulin G4 (IgG4) dipsticks. The concordance of the results of the rapid test (comprising three dipsticks) with a commercial IgG-enzyme-linked immunosorbent assay (ELISA) (Cypress Diagnostics, Belgium) was compared against the concordance of two other commercial IgG-ELISA kits (Bordier, Switzerland and NovaTec, Germany) with the Cypress kit...
November 6, 2017: American Journal of Tropical Medicine and Hygiene
https://www.readbyqxmd.com/read/29118011/comparative-genome-analysis-of-programmed-dna-elimination-in-nematodes
#11
Jianbin Wang, Shenghan Gao, Yulia Mostovoy, Yuanyuan Kang, Maxim Zagoskin, Yongqiao Sun, Bing Zhang, Laura K White, Alice Easton, Thomas B Nutman, Pui-Yan Kwok, Songnian Hu, Martin K Nielsen, Richard E Davis
Programmed DNA elimination is a developmentally regulated process leading to the reproducible loss of specific genomic sequences. DNA elimination occurs in unicellular ciliates and a variety of metazoans, including invertebrates and vertebrates. In metazoa, DNA elimination typically occurs in somatic cells during early development, leaving the germline genome intact. Reference genomes for metazoa that undergo DNA elimination are not available. Here, we generated germline and somatic reference genome sequences of the DNA eliminating pig parasitic nematode Ascaris suum and the horse parasite Parascaris univalens...
November 8, 2017: Genome Research
https://www.readbyqxmd.com/read/29114136/efficacy-of-zingiber-officinale-ethanol-extract-on-the-viability-embryogenesis-and-infectivity-of-toxocara-canis-eggs
#12
Nagwa Mostafa El-Sayed
This study evaluated the effect of Zingiber officinale (Z. officinale) ethanol extract on the viability, embryogenesis and infectivity Toxocara canis (T. canis) eggs. It was carried out both in vitro and in vivo. In the in vitro experiment, unembryonated T. canis eggs were incubated with 25, 50 and 100 mg/mL Z. officinale extract at 25 °C for 6, 12, and 24 h to assess the effect of Z. officinale on their viability and for two weeks to assess the effect of Z. officinale on their embryogenesis. In vivo experiment was performed to assess the effect of Z...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29114134/epidemiological-investigation-of-gastrointestinal-parasites-in-dog-populations-in-basra-province-southern-iraq
#13
Khawla B N Al-Jassim, Yasser S Mahmmod, Zainab M Salem, Azmi Al-Jubury
The understanding of the epidemiology of canine parasitic infections is necessary for an efficient control program to minimize the risk of zoonotic transmission. The objectives of this study were (1) to determine the prevalence of canine gastrointestinal helminths and protozoa in Basra province, Southern Iraq, and (2) to identify the association of epidemiological characteristics (age, breed, gender, and feed type) of dogs with the parasitic infections. A total of 93 fecal samples, collected in the period from December 2014 to June 2015, were examined macroscopically and microscopically for the presence of worm eggs and protozoal oocysts, using centrifugal flotation method...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29114122/dot-enzyme-linked-immunosorbent-assay-elisa-for-the-detection-of-toxocara-infection-using-a-rat-model
#14
Vachel Gay V Paller, Cyrelle M Besana, Isabel Kristine M Valdez
Toxocariasis is a zoonotic disease usually caused by dog and cat roundworms, Toxocara canis and T. cati. Detection and diagnosis is difficult in paratenic and accidental hosts, including humans, as they cannot be detected through conventional methods such as fecal examination. Diagnosis therefore relies on immunological methods and molecular methods such as enzyme-linked immunosorbent assay (ELISA) and Western Blot, which are both time-consuming and requires sophisticated equipment. In the Philippines, only a few studies are available on Toxocara seroprevalence...
December 2017: Journal of Parasitic Diseases: Official Organ of the Indian Society for Parasitology
https://www.readbyqxmd.com/read/29080769/efficacy-of-two-anthelmintic-treatments-spinosad-milbemycin-oxime-and-ivermectin-praziquantel-in-dogs-with-natural-toxocara-spp-infection
#15
Rafael Heredia Cardenas, Camilo Romero Núñez, Laura Miranda Contreras
Toxocara canis is one of the most important zoonotic parasites of dogs. The aim of the present study was to compare the efficacy of spinosad/milbemycin oxime and ivermectin/praziquantel in dogs naturally infected with Toxocara spp. We studied 200 dogs with a positive diagnosis of Toxocara spp. Through coproparasitoscopic analysis, two study groups of 100 dogs each were assigned: spinosad/milbemycin oxime at a dose of 30-60mg/kg and 0.75-1.0mg/kg, respectively, or ivermectin/praziquantel administered at a dose of 0...
November 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29080756/diagnostic-strategies-to-reveal-covert-infections-with-intestinal-helminths-in-dogs
#16
Chris Adolph, Sharon Barnett, Melissa Beall, Jason Drake, David Elsemore, Jennifer Thomas, Susan Little
Intestinal helminths are common in dogs in the United States, particularly non-treated dogs in animal shelters, but surveys by fecal flotation may underestimate their prevalence. To determine the prevalence of intestinal helminths and evaluate the ability of fecal flotation and detection of nematode antigen to identify those infections, contents of the entire gastrointestinal tract of 97 adult (>1year) dogs previously identified for humane euthanasia at two animal control shelters in northeastern Oklahoma, USA, were screened...
November 30, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29035863/sero-detection-of-toxocara-canis-infection-in-human-with-t-canis-recombinant-arginine-kinase-cathepsin-l-1-and-tes-26-antigens
#17
Anju Varghese, Opinder K Raina, Dinesh Chandra, Bijay R Mirdha, Naresh H Kelawala, Jayesh B Solanki, Niranjan Kumar, Reghu Ravindran, Anandanarayanan Arun, Ajayta Rialch, Hniang Lalrinkima, Rohan N Kelawala, Subhamoy Samanta
Three recombinant antigens viz. arginine kinase, cathepsin L-1 and TES-26 of Toxocara canis were expressed in Escherichia coli and evaluated for their potential in the detection of T. canis larval infection in human in immunoglobulin G-enzyme linked immunosorbent assay (IgG-ELISA). Results of the IgG-ELISA with the above recombinant antigens were confirmed with commercially available IgG detection kit for T. canis infection used as a standard test. All three recombinant antigens were 100% sensitive in the detection of positive cases (n = 6) of T...
December 20, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/29035857/humoral-response-of-mice-infected-with-toxocara-canis-following-different-infection-schemes
#18
Jan Novák, Lucie Panská, Tomáš Macháček, Libuše Kolářová, Petr Horák
The study was focused on the dynamics of humoral response to Toxocara canis excretory-secretory antigens (TES antigens) in mice experimentally infected by T. canis L3 larvae in different ways. In particular, we compared the effect of infection with two doses of 1000 larvae vs. repeated infections with a low number of larvae (daily infection with 10 larvae and weekly infection with 100 larvae in the course of 22 weeks). In ELISA, all infections, including both schemes with lower larval doses, elicited significant antibody response...
December 20, 2017: Acta Parasitologica
https://www.readbyqxmd.com/read/29020386/seroprevalence-of-antibodies-to-toxocara-species-in-the-united-states-and-associated-risk-factors-2011-2014
#19
Eugene W Liu, Holly M Chastain, Sun Hee Shin, Ryan Wiegand, Deanna Kruszon-Moran, Sukwan Handali, Jeffrey L Jones
Background: Toxocariasis results from infection with larval stages of a dog and cat intestinal nematode and causes human morbidity. The current US estimate of Toxocara exposure is 13.9% (NHANES III 1988-1994). Methods: We used a multiplex bead based assay (Tc-CTL-1MBA) with purified Toxocara canis antigen to estimate Toxocara antibody seroprevalence in serum of 13,509 persons six years and older from the National Health and Nutrition Examination Survey (NHANES), 2011-2014 and identified seropositivity risk factors...
September 4, 2017: Clinical Infectious Diseases: An Official Publication of the Infectious Diseases Society of America
https://www.readbyqxmd.com/read/29016316/toxocara-seroprevalence-and-associated-risk-factors-in-the-united-states
#20
Andrew N Berrett, Lance D Erickson, Shawn D Gale, Allison Stone, Bruce L Brown, Dawson W Hedges
Caused by the parasitic nematodes Toxocara canis and cati, toxocariasis in humans can result in covert toxocariasis, ocular toxocariasis, visceral larval migrans, and neurotoxocariasis. A common infection, toxocariasis exposure varies widely within and between countries, with a previous estimate of Toxocara seroprevalence using data from 1988 to 1994 in the United States of approximately 13%. Age, poverty, sex, educational attainment, ethnicity, and region have been associated with Toxocara seroprevalence. In this study, we sought to determine the seroprevalence of and factors associated with Toxocara seropositivity in the United States using data from the National Health and Nutrition Examination Survey from 2011 to 2014 to provide a more recent estimate of Toxocara seroprevalence in the United States...
September 25, 2017: American Journal of Tropical Medicine and Hygiene
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