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Toxocara canis

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https://www.readbyqxmd.com/read/29733009/molecular-characterization-of-toxocara-spp-eggs-isolated-from-public-parks-and-playgrounds-in-shiraz-iran
#1
M Choobineh, F Mikaeili, S M Sadjjadi, S Ebrahimi, S Iranmanesh
Human toxocariasis, a worldwide parasitic disease, is caused by the larval stage of intestinal nematodes of dogs and cats, namely Toxocara canis and Toxocara cati. Human infection occurs by the accidental ingestion of embryonated eggs present in the soil, vegetables or on other contaminated surfaces, as well as via consumption of uncooked paratenic hosts, such as bird meat and giblets. The objective of this study was to evaluate the contamination of soil in public parks and playgrounds in Shiraz using microscopy and molecular methods...
May 7, 2018: Journal of Helminthology
https://www.readbyqxmd.com/read/29727708/artemisinin-and-its-derivatives-in-treating-helminthic-infections-beyond-schistosomiasis
#2
REVIEW
Nelson Siukei Lam, Xinxin Long, Xin-Zhuan Su, Fangli Lu
The World Health Organization estimated that more than 1.5 billion people are infected with soil-transmitted helminths globally, and foodborne trematodiases in humans cause ∼2 million life-years lost to disability and death worldwide every year. Investment in prevention, treatment, and awareness of helminth infections and discovery of new, safe, effective, and affordable anti-helminth drugs are urgently needed. Artemisinin (ART) and its derivatives have been widely used to treat malaria and other protozoan infections; they also possess activities against helminths...
May 1, 2018: Pharmacological Research: the Official Journal of the Italian Pharmacological Society
https://www.readbyqxmd.com/read/29668139/-zoonotic-intestinal-nematodes-in-dogs-from-public-parks-in-yucat%C3%A3-n-m%C3%A3-xico
#3
Rodrigo Adán Medina-Pinto, Roger Iván Rodríguez-Vivas, Manuel Emilio Bolio-González
INTRODUCTION: Dogs represent a potential public health risk because of the natural transmission of zoonotic parasitic infections. OBJECTIVE: To estimate the frequency and to determine factors associated with the presence of intestinal nematode eggs in dog feces collected in public parks of Mérida,Yucatán, México. MATERIALS AND METHODS: A total of 100 dog fecal samples collected from 20 public parks in two areas of Mérida were analyzed...
March 15, 2018: Biomédica: Revista del Instituto Nacional de Salud
https://www.readbyqxmd.com/read/29665827/effect-of-selected-gastrointestinal-parasites-and-viral-agents-on-fecal-s100a12-concentrations-in-puppies-as-a-potential-comparative-model
#4
Romy M Heilmann, Aurélien Grellet, Niels Grützner, Shannon M Cranford, Jan S Suchodolski, Sylvie Chastant-Maillard, Jörg M Steiner
BACKGROUND: Previous data suggest that fecal S100A12 has clinical utility as a biomarker of chronic gastrointestinal inflammation (idiopathic inflammatory bowel disease) in both people and dogs, but the effect of gastrointestinal pathogens on fecal S100A12 concentrations is largely unknown. The role of S100A12 in parasite and viral infections is also difficult to study in traditional animal models due to the lack of S100A12 expression in rodents. Thus, the aim of this study was to evaluate fecal S100A12 concentrations in a cohort of puppies with intestinal parasites (Cystoisospora spp...
April 17, 2018: Parasites & Vectors
https://www.readbyqxmd.com/read/29651227/a-case-of-atopic-dermatitis-caused-by-ascaris-lumbricoides-infection
#5
Rosanna Qualizza, Laura M Losappio, Fabiana Furci
Background: Parasite infections stimulate total and specific IgE production that, in the case of Toxocara canis infection, corresponds to chronic allergic symptoms. There may also be other infections which have similar symptoms, such as Ascaris lumbricoides infection. Ascaris lumbricoides is a large nematode that causes abdominal pain, nausea, vomiting, bloating, anorexia and intermittent diarrhoea. Patients with ascaridiasis and high IgE levels may also have allergy-like symptoms such as asthma, urticaria and atopic dermatitis...
2018: Clinical and Molecular Allergy: CMA
https://www.readbyqxmd.com/read/29574514/longitudinal-study-for-anthelmintic-efficacy-against-intestinal-helminths-in-naturally-exposed-lithuanian-village-dogs-critical-analysis-of-feasibility-and-limitations
#6
Ž Vienažindienė, D E Joekel, R Schaper, P Deplazes, M Šarkūnas
The efficacy of anthelmintic treatment at 1, 3, and 6 month intervals was evaluated in a prospective controlled field study with naturally exposed Lithuanian village dogs by monthly coproscopy during 1 year. A placebo-treated control group (C) (n = 202) and groups treated with two broad-spectrum anthelmintics, febantel/pyrantel-embonate/praziquantel (Drontal® Plus, Bayer) (D1, D3, D6; n = 113-117) and emodepside/praziquantel (Profender®, Bayer) (P1, P3, P6; n = 114-119), were included. At the beginning of the study, eggs of Toxocara canis (4...
March 25, 2018: Parasitology Research
https://www.readbyqxmd.com/read/29559144/endocrine-immune-interactions-during-chronic-toxocariasis-caused-by-toxocara-canis-in-a-murine-model-new-insights-into-the-pathophysiology-of-an-old-infection
#7
Víctor Hugo Del Río-Araiza, Karen Elizabeth Nava-Castro, Fernando Alba-Hurtado, Andrés Quintanar-Stephano, Marco Antonio Muñoz-Guzmán, Olga CUenca-Micò, Jorge Morales-Montor
Toxocara canis is the helminth causing Toxocariasis, a parasitic disease with medical and veterinary implications. Their final host are members of the family Canidae and as paratenic hosts, most of the mammals are sensitive (man, rat, mouse, among others). It has been reported that a pituitary hormone, prolactin, it is responsible for reactivation and migration of larvae to the uterus and mammary gland during the last third of gestation in bitches. In addition, this hormone has been shown to play an important role in the regulation of the immune response...
March 15, 2018: Veterinary Parasitology
https://www.readbyqxmd.com/read/29472889/clinical-and-magnetic-resonance-imaging-findings-of-neurotoxocariasis
#8
REVIEW
Sofia S Sánchez, Hector H García, Alessandra Nicoletti
Human toxocariasis is one of the most prevalent helminthiases worldwide. Toxocara canis larvae can cross the blood-brain barrier leading to the neurotoxocariasis. The clinical presentation consists of a wide spectrum of neurological manifestations, but asymptomatic infection is probably common. Neurotoxocariasis is not a frequent diagnosis probably due to the non-specific nature of its symptoms as well as the lack of confirmatory diagnostic tests. Diagnosis of neurotoxocariasis is based on the presence of a high titer of anti- Toxocara antibody in the cerebrospinal fluid or in the serum, presence of eosinophilia in the serum or cerebrospinal fluid, and clinical and radiological improvement after anthelmintic therapy; however, universally accepted diagnostic criteria are lacking...
2018: Frontiers in Neurology
https://www.readbyqxmd.com/read/29445372/robust-phenotypic-activation-of-eosinophils-during-experimental-toxocara-canis-infection
#9
Joice Margareth de Almeida Rodolpho, Luciana Camillo, Márcio Sobreira Silva Araújo, Elaine Speziali, Jordana Grazziela Coelho-Dos-Reis, Ricardo de Oliveira Correia, Débora Meira Neris, Olindo Assis Martins-Filho, Andréa Teixeira-Carvalho, Fernanda de Freitas Anibal
Eosinophils are multifunctional cells that have cytotoxic proinflammatory activities and stimulate CD4+ T-cells in experimental models of allergy and parasitic infections. Eosinophils, when exposed to antigens, are activated, expressing the CD38/CD69 molecules and exhibited increased expression of major histocompatibility complex (MHC-II), CD80 and CD86, suggesting they play a role upon Toxocara canis antigen stimulation. In the present study, we evaluated the profile of eosinophils using conventional and image flow cytometry upon experimental T...
2018: Frontiers in Immunology
https://www.readbyqxmd.com/read/29424034/total-and-toxocara-canis-larval-excretory-secretory-antigen-and-allergen-specific-ige-in-atopic-and-non-atopic-dogs
#10
Lena L M N Zwickl, Deborah E Joekel, Nina M Fischer, Ana Rostaher, Kristian Thamsborg, Peter Deplazes, Claude Favrot
BACKGROUND: Total IgE concentrations are higher in dogs than in humans. Persistent Toxocara canis larval infection is prevalent in dogs and is associated with substantial specific antibody reactions. A correlation, however, between total IgE and T. canis-specific antibody levels in dogs has not been evaluated. OBJECTIVES: To determine the relationship between total IgE, T. canis-specific IgG and IgE, and allergen-specific IgE levels in atopic and non-atopic dogs, and to evaluate possible confounding factors...
February 9, 2018: Veterinary Dermatology
https://www.readbyqxmd.com/read/29423531/tissue-expression-pattern-of-abcg-transporter-indicates-functional-roles-in-reproduction-of-toxocara-canis
#11
Yong-Li Luo, Guang-Xu Ma, Yong-Fang Luo, Ce-Yan Kuang, Ai-Yun Jiang, Guo-Qing Li, Rong-Qiong Zhou
Toxocara canis is a zoonotic parasite with worldwide distribution. ATP-binding cassette (ABC) transporters are integral membrane proteins which involve in a range of biological processes in various organisms. In present study, the full-length coding sequence of abcg-5 gene of T. canis (Tc-abcg-5) was cloned and characterized. A 633 aa polypeptide containing two conserved Walker A and Walker B motifs was predicted from a continuous 1902 nt open reading frame. Quantitative real-time PCR was employed to determine the transcriptional levels of Tc-abcg-5 gene in adult male and female worms, which indicated high mRNA level of Tc-abcg-5 in the reproductive tract of adult female T...
March 2018: Parasitology Research
https://www.readbyqxmd.com/read/29388550/leishmania-infantum-dirofilaria-spp-and-other-endoparasite-infections-in-kennel-dogs-in-central-italy
#12
Federica Sauda, Livia Malandrucco, Gladia Macrì, Manuela Scarpulla, Claudio De Liberato, Giuliana Terracciano, Gianluca Fichi, Federica Berrilli, Stefania Perrucci
Prevalence and risk factors of Leishmania infantum, Dirofilaria spp. and other potentially zoonotic or canine-specific endoparasite infections were assessed in 639 kennel dogs from central Italy. To this end, individual blood and fecal samples were examined using parasitological, immunological and molecular techniques. The presence of compatible clinical pictures, as well as age and gender were considered as putative risks factors. To evaluate risk factors, multivariable analysis with logistic regression and univariable analysis with a Chi square test and a Fischer's exact test were performed...
2018: Parasite: Journal de la Société Française de Parasitologie
https://www.readbyqxmd.com/read/29364534/italian-multicentre-study-found-infectious-and-vaccine-preventable-diseases-in-children-adopted-from-africa-and-recommends-prompt-medical-screening
#13
Elena Chiappini, Mauro Zaffaroni, Martina Bianconi, Giuseppina Veneruso, Nicolino Grasso, Silvia Garazzino, Rosangela Arancio, Piero Valentini, Anna Ficcadenti, Maria Rosalia Da Riol, Simona La Placa, Luisa Galli, Maurizio de Martino, Gianni Bona
AIM: This study evaluated the prevalence of infectious diseases and immunisation status of children adopted from Africa. METHODS: We studied 762 African children referred to 11 Italian paediatric centres in 2009-2015. Clinical and laboratory data were retrospectively collected and analysed. RESULTS: The median age of the children (60.3% males) was 3 years and 6 months, 52.6% came from Ethiopia and 50.1% had at least one infectious disease...
January 24, 2018: Acta Paediatrica
https://www.readbyqxmd.com/read/29351076/parasites-in-stray-dogs-from-italy-prevalence-risk-factors-and-management-concerns
#14
Claudio De Liberato, Federica Berrilli, Livio Odorizi, Roberto Scarcella, Marco Barni, Cristina Amoruso, Alessia Scarito, Margherita Montalbano Di Filippo, Andrea Carvelli, Francesca Iacoponi, Paola Scaramozzino
Parasites are among the most common pathogens recorded in dogs. High prevalence rates are usually reported in stray and shelter dogs, as these animals are less likely to be tested and treated. In this study a survey was carried out on intestinal and lung parasites of stray dogs at the moment of the admission in a shelter in Central Italy. In the period June 2014-June 2015, 262 individual faecal samples were examined. Twelve parasitic taxa were detected. Helminths were more prevalent than protozoa (61.8% and 25...
March 26, 2018: Acta Parasitologica
https://www.readbyqxmd.com/read/29274214/helminth-infections-in-faecal-samples-of-apennine-wolf-canis-lupus-italicus-and-marsican-brown-bear-ursus-arctos-marsicanus-in-two-protected-national-parks-of-central-italy
#15
Barbara Paoletti, Raffaella Iorio, Donato Traversa, Cristina E Di Francesco, Leonardo Gentile, Simone Angelucci, Cristina Amicucci, Roberto Bartolini, Marianna Marangi, Angela Di Cesare
This article reports the results of a copromicroscopic and molecular investigation carried out on faecal samples of wolves (n=37) and brown bears (n=80) collected in two protected national parks of central Italy (Abruzzo Region). Twenty-three (62.2%) samples from wolves were positive for parasite eggs. Eight (34.78%) samples scored positive for single infections, i.e. E. aerophilus (21.74%), Ancylostoma/Uncinaria (4.34%), Trichuris vulpis (4.34%), T. canis (4.34%). Polyspecific infections were found in 15 samples (65...
2017: Annals of Parasitology
https://www.readbyqxmd.com/read/29273062/enhanced-expressions-of-neurodegeneration-associated-factors-ups-impairment-and-excess-a%C3%AE-accumulation-in-the-hippocampus-of-mice-with-persistent-cerebral-toxocariasis
#16
Chia-Mei Chou, Yueh-Lun Lee, Chien-Wei Liao, Ying-Chieh Huang, Chia-Kwung Fan
BACKGROUND: Toxocariasis is a worldwide zoonotic parasitic disease mainly caused by Toxocara canis. Humans can be infected by accidental ingestion of T. canis embryonated ovum-contaminated food, water, or encapsulated larvae in paratenic hosts' viscera or meat. Since humans and mice are paratenic hosts of T. canis, the wandering larvae might cause mechanical tissue damage and excretory-secretory antigens may trigger inflammatory injuries to local organs. Long-term residence of T. canis larvae in a paratenic host's brain may cause cerebral toxocariasis (CT) that contributes to cerebral damage, neuroinflammation and neuropsychiatric disorders in mice and clinical patients...
December 22, 2017: Parasites & Vectors
https://www.readbyqxmd.com/read/29243027/lactobacillus-rhamnosus-reduces-parasite-load-on-toxocara-canis-experimental-infection-in-mice-but-has-no-effect-on-the-parasite-in-vitro
#17
Débora Liliane Walcher, Luis Augusto Xavier Cruz, Paula de Lima Telmo, Lourdes Helena Rodrigues Martins, Luciana Farias da Costa de Avila, Maria Elisabeth Aires Berne, Carlos James Scaini
Human toxocariasis is a neglected global parasitic zoonosis. The efficacy of drug treatment for this disease has been hindered by the biological complexity of the main etiological agent, the nematode Toxocara canis. Experimental studies have shown the potential of probiotics to promote a reduction in the parasite load of T. canis larvae. This study aimed to evaluate the effect of probiotic Lactobacillus rhamnosus ATCC 7469 on the parasite load of BALB/c mice with acute toxocariasis and evaluate the direct effect of this probiotic on T...
February 2018: Parasitology Research
https://www.readbyqxmd.com/read/29221930/in-vitro-effect-of-chrysosporium-indicum-and-chrysosporium-keratinophylum-on-toxocara-canis-eggs
#18
María V Bojanich, Juan A Basualdo, Gustavo Giusiano
The degree of antagonism exercised by fungi on geohelminth development varies according to the morphological alterations caused by different fungal species. Saprophytic fungi may exert ovicidal or ovistatic effects. The aim of this study was to apply scanning electron microscopy (SEM) to observe the action of two soil saprophytic species of Chrysosporium (C. indicum and C. keratinophylum) on Toxocara canis eggs. The fungal strains to be tested were incubated for 28 days at 28°C in 2% water agar with a suspension of unembryonated T...
December 5, 2017: Revista Argentina de Microbiología
https://www.readbyqxmd.com/read/29173542/regression-models-to-assess-the-risk-factors-of-canine-gastrointestinal-parasitism
#19
I Symeonidou, A Ι Gelasakis, K V Arsenopoulos, R Schaper, E Papadopoulos
Gastrointestinal parasites, protozoa and helminths, remain a common important finding in dogs presented to veterinary medical practices. Moreover, dogs may play an active role in the transmission of enteric parasites to humans, given their cohabitation, making canine gastrointestinal parasitism an issue of major concern for public health. To get an overview of the current state of canine gastrointestinal parasites' prevalence in Greece, a total of 1036 faecal samples were collected from dogs either presented in veterinary clinics or in animal shelters...
December 15, 2017: Veterinary Parasitology
https://www.readbyqxmd.com/read/29160521/migration-pattern-of-toxocara-canis-larvae-in-experimentally-infected-male-and-female-rattus-norvegicus
#20
Sergio Vieira Dos Santos, Felipe Henrique Yazawa Santos, Susana Angelica Zevallos Lescano, Daniel Maurício Dos Santos, Érico da Silva Tiago, Gabriela Rodrigues E Fonseca, Manoel Carlos Sampaio de Almeida Ribeiro, Pedro Paulo Chieffi
No abstract text is available yet for this article.
September 2017: Revista da Sociedade Brasileira de Medicina Tropical
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