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https://www.readbyqxmd.com/read/29681996/computer-aided-diagnosis-of-acute-lymphoblastic-leukaemia
#1
REVIEW
Sarmad Shafique, Samabia Tehsin
Leukaemia is a form of blood cancer which affects the white blood cells and damages the bone marrow. Usually complete blood count (CBC) and bone marrow aspiration are used to diagnose the acute lymphoblastic leukaemia. It can be a fatal disease if not diagnosed at the earlier stage. In practice, manual microscopic evaluation of stained sample slide is used for diagnosis of leukaemia. But manual diagnostic methods are time-consuming, less accurate, and prone to errors due to various human factors like stress, fatigue, and so forth...
2018: Computational and Mathematical Methods in Medicine
https://www.readbyqxmd.com/read/29678977/minimizing-icu-neurological-dysfunction-with-dexmedetomidine-induced-sleep-mindds-protocol-for-a-randomised-double-blind-parallel-arm-placebo-controlled-trial
#2
Kenneth T Shelton, Jason Qu, Federico Bilotta, Emery N Brown, Gaston Cudemus, David A D'Alessandro, Hao Deng, Alan DiBiasio, Jacob A Gitlin, Eunice Y Hahm, Lauren E Hobbs, Timothy T Houle, Reine Ibala, Marco Loggia, Kara J Pavone, Shahzad Shaefi, George Tolis, M Brandon Westover, Oluwaseun Akeju
INTRODUCTION: Delirium, which is prevalent in postcardiac surgical patients, is an acute brain dysfunction characterised by disturbances in attention, awareness and cognition not explained by a pre-existing neurocognitive disorder. The pathophysiology of delirium remains poorly understood. However, basic science and clinical studies suggest that sleep disturbance may be a modifiable risk factor for the development of delirium. Dexmedetomidine is a α-2A adrenergic receptor agonist medication that patterns the activity of various arousal nuclei similar to sleep...
April 20, 2018: BMJ Open
https://www.readbyqxmd.com/read/29676947/intravenous-chemotherapy-compounding-errors-in-a-follow-up-pan-canadian-observational-study
#3
Rachel E Gilbert, Melissa C Kozak, Roxanne B Dobish, Venetia C Bourrier, Paul M Koke, Vishal Kukreti, Heather A Logan, Anthony C Easty, Patricia L Trbovich
PURPOSE: Intravenous (IV) compounding safety has garnered recent attention as a result of high-profile incidents, awareness efforts from the safety community, and increasingly stringent practice standards. New research with more-sensitive error detection techniques continues to reinforce that error rates with manual IV compounding are unacceptably high. In 2014, our team published an observational study that described three types of previously unrecognized and potentially catastrophic latent chemotherapy preparation errors in Canadian oncology pharmacies that would otherwise be undetectable...
April 20, 2018: Journal of Oncology Practice
https://www.readbyqxmd.com/read/29661165/midwives-perceptions-on-using-a-fetoscope-and-doppler-for-fetal-heart-rate-assessments-during-labor-a-qualitative-study-in-rural-tanzania
#4
Paschal Francis Mdoe, Hege Langli Ersdal, Estomih Mduma, Robert Moshiro, Hussein Kidanto, Columba Mbekenga
BACKGROUND: The Doppler is thought to be more comfortable and effective compared to the fetoscope for assessing the fetal heart rate (FHR) during labor. However, in a rural Tanzanian hospital, midwives who had easy access to both devices mostly used fetoscope. This study explored midwives' perception of factors influencing their preference for using either a Pinard fetoscope or a FreePlay wind-up Doppler for intermittent FHR monitoring. METHODS: Midwives who had worked for at least 6 months in the labor ward were recruited...
April 16, 2018: BMC Pregnancy and Childbirth
https://www.readbyqxmd.com/read/29660010/costs-for-breast-cancer-care-in-the-military-health-system-an-analysis-by-benefit-type-and-care-source
#5
Yvonne L Eaglehouse, Janna Manjelievskaia, Stephanie Shao, Derek Brown, Keith Hofmann, Patrick Richard, Craig D Shriver, Kangmin Zhu
Introduction: Breast cancer care imposes a significant financial burden to U.S. healthcare systems. Health services factors, such as insurance benefit type and care source, may impact costs to the health system. Beneficiaries in the U.S. Military Health System (MHS) have universal healthcare coverage and access to a network of military facilities (direct care) and private practices (purchased care). This study aims to quantify and compare breast cancer care costs to the MHS by insurance benefit type and care source...
April 11, 2018: Military Medicine
https://www.readbyqxmd.com/read/29657418/-androctonus-genus-species-in-arid-regions-ecological-niche-models-geographical-distributions-and-envenomation-risk
#6
Moulay Abdelmonaim El Hidan, Oulaid Touloun, Abdellah Bouazza, Mehdi Ait Laaradia, Ali Boumezzough
Aim: The objective of this study was to establish environmental factors related to scorpion species occurrence and their current potential geographic distributions in Morocco, to produce a current envenomation risk map and also to assess the human population at risk of envenomation. Materials and Methods: In this study, 71 georeferenced points for all scorpion species and nine environmental indicators were used to generate species distribution models in Maxent (maximum entropy modeling of species geographic distributions) version 3...
March 2018: Veterinary World
https://www.readbyqxmd.com/read/29650698/credit-assignment-in-a-motor-decision-making-task-is-influenced-by-agency-and-not-sensorimotor-prediction-errors
#7
Darius E Parvin, Samuel D McDougle, Jordan A Taylor, Richard B Ivry
Failures to obtain reward can occur from errors in action selection or action execution. Recently, we observed marked differences in choice behavior when the failure to obtain a reward was attributed to errors in action execution compared to errors in action selection (McDougle et al. , 2016). Specifically, participants appeared to solve this credit assignment problem by discounting outcomes in which the absence of reward was attributed to errors in action execution. Building on recent evidence indicating relatively direct communication between the cerebellum and basal ganglia, we hypothesized that cerebellar-dependent sensory-prediction errors (SPEs), a signal indicating execution failure, could attenuate value updating within a basal-ganglia dependent reinforcement learning system...
April 12, 2018: Journal of Neuroscience: the Official Journal of the Society for Neuroscience
https://www.readbyqxmd.com/read/29643628/pediatric-critical-incidents-reported-over-15-years-at-a-tertiary-care-teaching-hospital-of-a-developing-country
#8
Shemila Abbasi, Fauzia Anis Khan, Sobia Khan
Background and Aims: The role of critical incident (CI) reporting is well established in improving patient safety but only a limited number of available reports relate to pediatric incidents. Our aim was to analyze the reported CIs specific to pediatric patients in our database and to reevaluate the value of this program in addressing issues in pediatric anesthesia practice. Material and Methods: Incidents related to pediatric population from neonatal period till the age of 12 years were selected...
January 2018: Journal of Anaesthesiology, Clinical Pharmacology
https://www.readbyqxmd.com/read/29643419/author-correction-synergistic-effect-of-human-bone-morphogenic-protein-2-and-mesenchymal-stromal-cells-on-chronic-wounds-through-hypoxia-inducible-factor-1-%C3%AE-induction
#9
Sabine François, Véronique Eder, Karim Belmokhtar, Marie-Christine Machet, Luc Douay, Norbert-Claude Gorin, Marc Benderitter, Alain Chapel
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
April 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29643364/predictd-parallel-epigenomics-data-imputation-with-cloud-based-tensor-decomposition
#10
Timothy J Durham, Maxwell W Libbrecht, J Jeffry Howbert, Jeff Bilmes, William Stafford Noble
The Encyclopedia of DNA Elements (ENCODE) and the Roadmap Epigenomics Project seek to characterize the epigenome in diverse cell types using assays that identify, for example, genomic regions with modified histones or accessible chromatin. These efforts have produced thousands of datasets but cannot possibly measure each epigenomic factor in all cell types. To address this, we present a method, PaRallel Epigenomics Data Imputation with Cloud-based Tensor Decomposition (PREDICTD), to computationally impute missing experiments...
April 11, 2018: Nature Communications
https://www.readbyqxmd.com/read/29622785/author-correction-downregulation-of-parp1-transcription-by-promoter-associated-e2f4-rbl2-hdac1-brm-complex-contributes-to-repression-of-pluripotency-stem-cell-factors-in-human-monocytes
#11
Ewelina Wiśnik, Tomasz Płoszaj, Agnieszka Robaszkiewicz
A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper.
April 5, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29610981/speech-recognition-for-medical-dictation-overview-in-quebec-and-systematic-review
#12
REVIEW
Thomas G Poder, Jean-François Fisette, Véronique Déry
Speech recognition is increasingly used in medical reporting. The aim of this article is to identify in the literature the strengths and weaknesses of this technology, as well as barriers to and facilitators of its implementation. A systematic review of systematic reviews was performed using PubMed, Scopus, the Cochrane Library and the Center for Reviews and Dissemination through August 2017. The gray literature has also been consulted. The quality of systematic reviews has been assessed with the AMSTAR checklist...
April 3, 2018: Journal of Medical Systems
https://www.readbyqxmd.com/read/29606650/clinical-dental-faculty-members-perceptions-of-diagnostic-errors-and-how-to-avoid-them
#13
Cathy Nikdel, Kian Nikdel, Ana Ibarra-Noriega, Elsbeth Kalenderian, Muhammad F Walji
Diagnostic errors are increasingly recognized as a source of preventable harm in medicine, yet little is known about their occurrence in dentistry. The aim of this study was to gain a deeper understanding of clinical dental faculty members' perceptions of diagnostic errors, types of errors that may occur, and possible contributing factors. The authors conducted semi-structured interviews with ten domain experts at one U.S. dental school in May-August 2016 about their perceptions of diagnostic errors and their causes...
April 2018: Journal of Dental Education
https://www.readbyqxmd.com/read/29601529/assessing-the-health-care-risk-the-clinical-var-a-key-indicator-for-sound-management
#14
Enrique Jiménez-Rodríguez, José Manuel Feria-Domínguez, Alonso Sebastián-Lacave
Clinical risk includes any undesirable situation or operational factor that may have negative consequences for patient safety or capable of causing an adverse event (AE). The AE, intentional or unintentionally, may be related to the human factor, that is, medical errors (MEs). Therefore, the importance of the health-care risk management is a current and relevant issue on the agenda of many public and private institutions. The objective of the management has been evolving from the identification of AE to the assessment of cost-effective and efficient measures that improve the quality control through monitoring...
March 30, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29601462/incident-reporting-to-improve-patient-safety-the-effects-of-process-variance-on-pediatric-patient-safety-in-the-emergency-department
#15
Karen J OʼConnell, Kathy N Shaw, Richard M Ruddy, Prashant V Mahajan, Richard Lichenstein, Cody S Olsen, Tomohiko Funai, Stephen Blumberg, James M Chamberlain
OBJECTIVE: Medical errors threaten patient safety, especially in the pediatric emergency department (ED) where overcrowding, multiple handoffs, and workflow interruptions are common. Errors related to process variance involve situations that are not consistent with standard ED operations or routine patient care. SETTING/PARTICIPANTS: We performed a planned subanalysis of the Pediatric Emergency Care Applied Research Network incident reporting data classified as process variance events...
April 2018: Pediatric Emergency Care
https://www.readbyqxmd.com/read/29595399/functionality-of-a-novel-follitropin-alfa-pen-injector-results-from-human-factor-interactions-by-patients-and-nurses
#16
Helen Saunders, Laura de la Fuente Bitaine, Chriss Eftekhar, Colin M Howles, Johanna Glaser, Tina Hoja, Pablo Arriagada
OBJECTIVE: The main objective of this user experience testing study was to evaluate the impact of human factors on the use of a disposable pen containing follitropin alfa by patients and nurses with special focus on the convenience, safety and ease of use, in different types of stimulation protocols. METHODS: Infertile women trying to conceive, and specialist nurses were recruited across 6 European countries. In total 18 patients and 19 nurses took part in the testing, which included both nurse-patient pairings and in-depth interviews...
March 29, 2018: Expert Opinion on Drug Delivery
https://www.readbyqxmd.com/read/29593465/experience-of-a-tertiary-level-urology-center-in-the-clinical-urological-events-of-rare-and-very-rare-incidence-i-surgical-never-events-1-urological-wrong-surgery-catastrophes-and-disabling-complications
#17
Rabea A Gadelkareem
Introduction: Surgical never events are preventable harmful non-intentional human errors. Urology is a common surgical specialty for their occurrence. Patients and Methods: A retrospective search of our center's data was done during the period 2006-2016 for surgical never events. Each included case was studied for the primary diagnosis, procedure, and subspecialty, never event type and timing, needed extra-interventions, urologist/procedure proportioning, outcomes, and possible underlying causes of the event...
February 2018: Current Urology
https://www.readbyqxmd.com/read/29584628/evaluation-of-loss-due-to-storm-surge-disasters-in-china-based-on-econometric-model-groups
#18
Xue Jin, Xiaoxia Shi, Jintian Gao, Tongbin Xu, Kedong Yin
Storm surge has become an important factor restricting the economic and social development of China's coastal regions. In order to improve the scientific judgment of future storm surge damage, a method of model groups is proposed to refine the evaluation of the loss due to storm surges. Due to the relative dispersion and poor regularity of the natural property data (login center air pressure, maximum wind speed, maximum storm water, super warning water level, etc.), storm surge disaster is divided based on eight kinds of storm surge disaster grade division methods combined with storm surge water, hypervigilance tide level, and disaster loss...
March 27, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29579901/quantification-of-campylobacter-jejuni-contamination-on-chicken-carcasses-in-france
#19
Benjamin Duqué, Samuel Daviaud, Sandrine Guillou, Nabila Haddad, Jeanne-Marie Membré
Highly prevalent in poultry, Campylobacter is a foodborne pathogen which remains the primary cause of enteritis in humans. Several studies have determined prevalence and contamination level of this pathogen throughout the food chain. However it is generally performed in a deterministic way without considering heterogeneity of contamination level. The purpose of this study was to quantify, using probabilistic tools, the contamination level of Campylobacter spp. on chicken carcasses after air-chilling step in several slaughterhouses in France...
April 2018: Food Research International
https://www.readbyqxmd.com/read/29576459/simple-and-efficient-thermal-calibration-for-mems-gyroscopes
#20
Alexis Nez, Laetitia Fradet, Pierre Laguillaumie, Tony Monnet, Patrick Lacouture
Gyroscopes are now becoming one of the most sold MEMS sensors, given that the many applications that require their use are booming. In the medical field, gyroscopes can be found in Inertial Measurement Units used for the development of clinical tools that are dedicated to human-movement monitoring. However, MEMS gyroscopes are known to suffer from a drift phenomenon, which is mainly due to temperature variations. This drift dramatically affects measurement capability, especially that of cheap MEMs gyroscopes...
March 22, 2018: Medical Engineering & Physics
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