keyword
MENU ▼
Read by QxMD icon Read
search

Human factors error

keyword
https://www.readbyqxmd.com/read/27913348/automatic-refinement-strategies-for-manual-initialization-of-object-trackers
#1
Hao Zhu, Fatih Porikli
Tracking objects across multiple frames is a wellinvestigated problem in computer vision. The majority of the existing algorithms assume an accurate initialization is readily available. However, in many real-life settings, in particular for applications where the video is streaming in real-time, the initialization has to be provided by a human operator. This limitation raises an inevitable uncertainty issue. Here, we first collect a large and new dataset of inputs that consists of more than 20K human initialization clicks, called as HIC, by several subjects under three practical user interface scenarios for the popular TB50 tracking benchmark...
December 1, 2016: IEEE Transactions on Image Processing: a Publication of the IEEE Signal Processing Society
https://www.readbyqxmd.com/read/27911420/-role-of-immunological-factors-in-the-development-of-myopic-choroidal-neovascularization
#2
A G Shchuko, N V Zaitseva, T N Yur'eva, E R Chernykh, I M Mikhalevich, A V Grigor'eva
AIM: To study the concentration of cytokines in the aqueous humor of the anterior chamber in patients with myopic choroidal neovascularization (mCNV) and to compare the results to their ophthalmic status. MATERIAL AND METHODS: A total of 19 patients (19 eyes) with mCNV treated with intravitreal ranibizumab were included in the study. The control group consisted of 15 patients (15 eyes) with myopia who had cataract surgery. Age, sex, and refractive error distribution were similar to that in the study group...
2016: Vestnik Oftalmologii
https://www.readbyqxmd.com/read/27907031/in-vitro-pre-clinical-validation-of-suicide-gene-modified-anti-cd33-redirected-chimeric-antigen-receptor-t-cells-for-acute-myeloid-leukemia
#3
Kentaro Minagawa, Muhammad O Jamil, Mustafa Al-Obaidi, Larisa Pereboeva, Donna Salzman, Harry P Erba, Lawrence S Lamb, Ravi Bhatia, Shin Mineishi, Antonio Di Stasi
BACKGROUND: Approximately fifty percent of patients with acute myeloid leukemia can be cured with current therapeutic strategies which include, standard dose chemotherapy for patients at standard risk of relapse as assessed by cytogenetic and molecular analysis, or high-dose chemotherapy with allogeneic hematopoietic stem cell transplant for high-risk patients. Despite allogeneic hematopoietic stem cell transplant about 25% of patients still succumb to disease relapse, therefore, novel strategies are needed to improve the outcome of patients with acute myeloid leukemia...
2016: PloS One
https://www.readbyqxmd.com/read/27902699/modeling-cellular-noise-underlying-heterogeneous-cell-responses-in-the-epidermal-growth-factor-signaling-pathway
#4
Kazunari Iwamoto, Yuki Shindo, Koichi Takahashi
Cellular heterogeneity, which plays an essential role in biological phenomena, such as drug resistance and migration, is considered to arise from intrinsic (i.e., reaction kinetics) and extrinsic (i.e., protein variability) noise in the cell. However, the mechanistic effects of these types of noise to determine the heterogeneity of signal responses have not been elucidated. Here, we report that the output of epidermal growth factor (EGF) signaling activity is modulated by cellular noise, particularly by extrinsic noise of particular signaling components in the pathway...
November 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27898094/crispr-cas9-aav-mediated-knock-in-at-nrl-locus-in-human-embryonic-stem-cells
#5
Xianglian Ge, Haitao Xi, Fayu Yang, Xiao Zhi, Yanghua Fu, Ding Chen, Ren-He Xu, Ge Lin, Jia Qu, Junzhao Zhao, Feng Gu
Clustered interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9)-mediated genome engineering technologies are sparking a new revolution in biological research. This technology efficiently induces DNA double strand breaks at the targeted genomic sequence and results in indel mutations by the error-prone process of nonhomologous end joining DNA repair or homologous recombination with a DNA repair template. The efficiency of genome editing with CRISPR/Cas9 alone in human embryonic stem cells is still low...
November 29, 2016: Molecular Therapy. Nucleic Acids
https://www.readbyqxmd.com/read/27897118/smoking-and-eye-pathologies-a-systemic-review-part-i-anterior-eye-segment-pathologies
#6
Małgorzata Nita, Andrzej Grzybowski
BACKGROUND: Tobacco smoking has detrimental influence on human health and is one of the leading causes of preventable mortality worldwide, associated with lung cancer, chronic obstructive lung disease and cardiovascular disease. AIM: The analysis of the influence of tobacco smoking on pathology of the anterior segment of the eye in adults and children. METHODS: A comprehensive review of the literature performed through MEDLINE and PubMed searches, was published during the period 2000-2016...
November 29, 2016: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/27893462/biallelic-mutations-in-irf8-impair-human-nk-cell-maturation-and-function
#7
Emily M Mace, Venetia Bigley, Justin T Gunesch, Ivan K Chinn, Laura S Angelo, Matthew A Care, Sheetal Maisuria, Michael D Keller, Sumihito Togi, Levi B Watkin, David F LaRosa, Shalini N Jhangiani, Donna M Muzny, Asbjørg Stray-Pedersen, Zeynep Coban Akdemir, Jansen B Smith, Mayra Hernández-Sanabria, Duy T Le, Graham D Hogg, Tram N Cao, Aharon G Freud, Eva P Szymanski, Sinisa Savic, Matthew Collin, Andrew J Cant, Richard A Gibbs, Steven M Holland, Michael A Caligiuri, Keiko Ozato, Silke Paust, Gina M Doody, James R Lupski, Jordan S Orange
Human NK cell deficiencies are rare yet result in severe and often fatal disease, particularly as a result of viral susceptibility. NK cells develop from hematopoietic stem cells, and few monogenic errors that specifically interrupt NK cell development have been reported. Here we have described biallelic mutations in IRF8, which encodes an interferon regulatory factor, as a cause of familial NK cell deficiency that results in fatal and severe viral disease. Compound heterozygous or homozygous mutations in IRF8 in 3 unrelated families resulted in a paucity of mature CD56dim NK cells and an increase in the frequency of the immature CD56bright NK cells, and this impairment in terminal maturation was also observed in Irf8-/-, but not Irf8+/-, mice...
November 28, 2016: Journal of Clinical Investigation
https://www.readbyqxmd.com/read/27890117/latent-error-detection-a-golden-two-hours-for-detection
#8
Justin R E Saward, Neville A Stanton
Undetected error in safety critical contexts generates a latent condition that can contribute to a future safety failure. The detection of latent errors post-task completion is observed in naval air engineers using a diary to record work-related latent error detection (LED) events. A systems view is combined with multi-process theories to explore sociotechnical factors associated with LED. Perception of cues in different environments facilitates successful LED, for which the deliberate review of past tasks within two hours of the error occurring and whilst remaining in the same or similar sociotechnical environment to that which the error occurred appears most effective...
March 2017: Applied Ergonomics
https://www.readbyqxmd.com/read/27888596/a-study-of-the-readiness-of-hospitals-for-implementation-of-high-reliability-organizations-model-in-tehran-university-of-medical-sciences
#9
Seyed Mohammad Hadi Mousavi, Hossein Dargahi, Sara Mohammadi
Creating a safe of health care system requires the establishment of High Reliability Organizations (HROs), which reduces errors, and increases the level of safety in hospitals. This model focuses on improving reliability through higher process design, building a culture of accreditation, and leveraging human factors. The present study intends to determine the readiness of hospitals for the establishment of HROs model in Tehran University of Medical Sciences from the viewpoint of managers of these hospitals...
October 2016: Acta Medica Iranica
https://www.readbyqxmd.com/read/27863620/paediatric-airway-foreign-body-the-human-factors-influencing-patient-safety-in-our-hospitals
#10
O C Okonkwo, A Simons, J Nichani
Foreign bodies in the pediatric airway are an uncommon emergency with a high morbidity and mortality rate. Morbidity ranges from 10 to 20% worldwide and this pathology accounts for up to 7% of accidental deaths in children under 4. Dealing with this emergency safely and effectively is complex, requiring a tight coupling of procedures and processes and optimal anesthetic and operating conditions to prevent errors. These factors are recognized by the World Health Organization as 'Human Factors'. We perform a multi-center assessment of human factors pertinent to this emergency...
December 2016: International Journal of Pediatric Otorhinolaryngology
https://www.readbyqxmd.com/read/27846212/quantifying-differences-and-similarities-in-whole-brain-white-matter-architecture-using-local-connectome-fingerprints
#11
Fang-Cheng Yeh, Jean M Vettel, Aarti Singh, Barnabas Poczos, Scott T Grafton, Kirk I Erickson, Wen-Yih I Tseng, Timothy D Verstynen
Quantifying differences or similarities in connectomes has been a challenge due to the immense complexity of global brain networks. Here we introduce a noninvasive method that uses diffusion MRI to characterize whole-brain white matter architecture as a single local connectome fingerprint that allows for a direct comparison between structural connectomes. In four independently acquired data sets with repeated scans (total N = 213), we show that the local connectome fingerprint is highly specific to an individual, allowing for an accurate self-versus-others classification that achieved 100% accuracy across 17,398 identification tests...
November 2016: PLoS Computational Biology
https://www.readbyqxmd.com/read/27845054/simultaneous-determination-of-plasma-total-homocysteine-and-methionine-by-liquid-chromatography-tandem-mass-spectrometry
#12
Yi Jiang, Brandon Mistretta, Sarah Elsea, Qin Sun
The sulfur-containing amino acid homocysteine is a cardiac risk factor and a biomarker for several inborn errors of metabolism in methionine synthesis. A simple LC-MS/MS method was developed and validated for determination of homocysteine and methionine in human plasma. Rapid separation was achieved using a reverse phase liquid chromatography. Mass spectrometry identification was performed in positive electrospray ionization mode for homocysteine and methionine. Accuracy, precision, linearity, recovery and sample stability were evaluated in the method validation...
November 12, 2016: Clinica Chimica Acta; International Journal of Clinical Chemistry
https://www.readbyqxmd.com/read/27832450/neural-correlates-of-correct-and-failed-response-inhibition-in-heavy-versus-light-social-drinkers-an-fmri-study-during-a-go-no-go-task-by-healthy-participants
#13
Salvatore Campanella, Julie Absil, Carina Carbia Sinde, Elisa Schroder, Philippe Peigneux, Mathieu Bourguignon, Mathieu Petieau, Thierry Metens, Mustapha Nouali, Serge Goldman, Guy Cheron, Paul Verbanck, Xavier Detiège
The ability to suppress responses that are inappropriate, as well as the mechanisms monitoring the accuracy of actions in order to compensate for errors, is central to human behavior. Neural alterations that prevent stopping an inaccurate response, combined with a decreased ability of error monitoring, are considered to be prominent features of alcohol abuse. Moreover, (i) alterations of these processes have been reported in heavy social drinkers (i.e. young healthy individuals who do not yet exhibit a state of alcohol dependence); and (ii) through longitudinal studies, these alterations have been shown to underlie subsequent disinhibition that may lead to future alcohol use disorders...
November 10, 2016: Brain Imaging and Behavior
https://www.readbyqxmd.com/read/27830239/human-factors-for-more-usable-and-safer-health-information-technology-where-are-we-now-and-where-do-we-go-from-here
#14
A Kushniruk, C Nohr, E Borycki
: A wide range of human factors approaches have been developed and adapted to healthcare for detecting and mitigating negative unexpected consequences associated with technology in healthcare (i.e. technology-induced errors). However, greater knowledge and wider dissemination of human factors methods is needed to ensure more usable and safer health information technology (IT) systems. OBJECTIVE: This paper reports on work done by the IMIA Human Factors Working Group and discusses some successful approaches that have been applied in using human factors to mitigate negative unintended consequences of health IT...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27830235/unintended-consequences-new-problems-new-solutions-contributions-from-2015
#15
R Koppel, Y Chen
OBJECTIVE: To select the best of the 2015 published papers on unintended consequences of healthcare information technology (HIT). METHOD: Literature searches in several areas of scholarship, including IT, human factors, evaluation studies, medical errors, medical informatics, and implementation science. Also, because the specific terms "unintended consequences" were not often included in abstracts and titles, a more nuanced search algorithm was developed. RESULTS: We identified 754 papers that had some empirical research on unintended consequences of HIT...
November 10, 2016: Yearbook of Medical Informatics
https://www.readbyqxmd.com/read/27826817/considerations-in-applying-compressed-sensing-to-in-vivo-phosphorus-mr-spectroscopic-imaging-of-human-brain-at-3t
#16
Gokce Hale Hatay, Muhammed Yildirim, Esin Ozturk-Isik
The purpose of this study was to apply compressed sensing method for accelerated phosphorus MR spectroscopic imaging ((31)P-MRSI) of human brain in vivo at 3T. Fast (31)P-MRSI data of five volunteers were acquired on a 3T clinical MR scanner using pulse-acquire sequence with a pseudorandom undersampling pattern for a data reduction factor of 5.33 and were reconstructed using compressed sensing. Additionally, simulated (31)P-MRSI human brain tumor datasets were created to analyze the effects of k-space sampling pattern, data matrix size, regularization parameters of the reconstruction, and noise on the compressed sensing accelerated (31)P-MRSI data...
November 8, 2016: Medical & Biological Engineering & Computing
https://www.readbyqxmd.com/read/27821317/can-a-pathological-complete-response-of-breast-cancer-after-neoadjuvant-chemotherapy-be-diagnosed-by-minimal-invasive-biopsy
#17
Joerg Heil, Benedikt Schaefgen, Peter Sinn, Hannah Richter, Aba Harcos, Christina Gomez, Anne Stieber, André Hennigs, Geraldine Rauch, Florian Schuetz, Christof Sohn, Andreas Schneeweiss, Michael Golatta
BACKGROUND: This study aimed to explore the ability of a minimal invasive biopsy to diagnose a pathological complete response (pCR = ypT0) in the breast. METHODS: Ultrasound-guided, vacuum-assisted, minimal invasive biopsy (VAB) was performed in 50 patients after neoadjuvant chemotherapy and before breast surgery. Negative predictive values (NPV) and false negative rates (FNR) to predict a pCR in surgical specimen were the main outcome measures. To assess the possible sampling error, the representativeness of the sample was evaluated by the biopsy performing physician (subjectively based on the visibility in ultrasound), by radiography of the biopsy specimen, and by the pathologist (based on histopathology)...
November 4, 2016: European Journal of Cancer
https://www.readbyqxmd.com/read/27819203/nutrigenomics-in-the-modern-era
#18
John C Mathers
The concept that interactions between nutrition and genetics determine phenotype was established by Garrod at the beginning of the 20th century through his ground-breaking work on inborn errors of metabolism. A century later, the science and technologies involved in sequencing of the human genome stimulated development of the scientific discipline which we now recognise as nutritional genomics (nutrigenomics). Much of the early hype around possible applications of this new science was unhelpful and raised expectations, which have not been realised as quickly as some would have hoped...
November 7, 2016: Proceedings of the Nutrition Society
https://www.readbyqxmd.com/read/27811524/objectively-measured-light-exposure-in-emmetropic-and-myopic-adults
#19
Lisa A Ostrin
PURPOSE: Light exposure has a close link with numerous aspects of human physiology including circadian rhythm, mood disorders, metabolism, and eye growth. Here, a lightweight wrist-worn device was employed to continuously measure light exposure and activity across seasons and between refractive error groups to assess objectively measured differences and compare with subjectively reported data. METHODS: Subjects, aged 21-65 years (n = 55), wore an actigraph device (Actiwatch Spectrum) continuously for 14 days to quantify light exposure, activity, and sleep...
November 1, 2016: Optometry and Vision Science: Official Publication of the American Academy of Optometry
https://www.readbyqxmd.com/read/27793404/load-adaptive-bone-remodeling-simulations-reveal-osteoporotic-microstructural-and-mechanical-changes-in-whole-human-vertebrae
#20
Sandro D Badilatti, Patrik Christen, Ian Parkinson, Ralph Müller
Osteoporosis is a major medical burden and its impact is expected to increase in our aging society. It is associated with low bone density and microstructural deterioration. Treatments are available, but the critical factor is to define individuals at risk from osteoporotic fractures. Computational simulations investigating not only changes in net bone tissue volume, but also changes in its microstructure where osteoporotic deterioration occur might help to better predict the risk of fractures. In this study, bone remodeling simulations with a mechanical feedback loop were used to predict microstructural changes due to osteoporosis and their impact on bone fragility from 50 to 80 years of age...
October 13, 2016: Journal of Biomechanics
keyword
keyword
63909
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"