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Cognitive error emergency

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https://www.readbyqxmd.com/read/29333611/cognitive-dysfunction-after-generalized-tonic-clonic-status-epilepticus-in-adults
#1
K N Power, A Gramstad, N E Gilhus, K O Hufthammer, B A Engelsen
OBJECTIVES: Generalized tonic-clonic status epilepticus (GTC-SE) is considered a risk for cognitive impairment. Research with standardized tools is scarce and non-conclusive. We systematically assessed short-term and long-term cognitive function after GTC-SE. MATERIALS AND METHODS: Thirty-three patients were tested after the clinical post-ictal phase of GTC-SE (timepoint 1) and again after 1 year (timepoint 2). Twenty controls were examined with the same tests...
January 14, 2018: Acta Neurologica Scandinavica
https://www.readbyqxmd.com/read/29331842/predicting-1-year-disability-and-mortality-of-injured-older-adults
#2
Alvin D Jeffery, Mary S Dietrich, Cathy A Maxwell
PURPOSE: The growing incidence of elderly patients injured from falls, combined with a growing understanding of the contribution of cognition and frailty to mortality, prompted this work. Our objective was to develop a clinical risk prediction model for prognosticating disability and mortality among injured older adults 1 year after hospitalization. METHODS: Secondary analysis of prospective longitudinal data from an urban Level 1 trauma center. A proportional odds regression model was used to model mortality and functional status as ordinal outcomes...
January 6, 2018: Archives of Gerontology and Geriatrics
https://www.readbyqxmd.com/read/29317467/evaluating-team-decision-making-as-an-emergent-phenomenon
#3
John Kinnear, Nick Wilson, Anthony O'Dwyer
BACKGROUND: The complexity of modern clinical practice has highlighted the fallibility of individual clinicians' decision-making, with effective teamwork emerging as a key to patient safety. Dual process theory is widely accepted as a framework for individual decision-making, with type 1 processes responsible for fast, intuitive and automatic decisions and type 2 processes for slow, analytical decisions. However, dual process theory does not explain cognition at the group level, when individuals act in teams...
January 9, 2018: Postgraduate Medical Journal
https://www.readbyqxmd.com/read/29283079/differential-contributions-of-selective-attention-and-sensory-integration-to-driving-performance-in-healthy-aging-and-alzheimer-s-disease
#4
Umesh M Venkatesan, Elena K Festa, Brian R Ott, William C Heindel
OBJECTIVES: Patients with Alzheimer's disease (AD) demonstrate deficits in cross-cortical feature binding distinct from age-related changes in selective attention. This may have consequences for driving performance given its demands on multisensory integration. We examined the relationship of visuospatial search and binding to driving in patients with early AD and elderly controls (EC). METHODS: Participants (42 AD; 37 EC) completed search tasks requiring either luminance-motion (L-M) or color-motion (C-M) binding, analogs of within and across visual processing stream binding, respectively...
December 28, 2017: Journal of the International Neuropsychological Society: JINS
https://www.readbyqxmd.com/read/29194059/self-reported-mild-traumatic-brain-injuries-in-relation-to-rumination-and-depressive-symptoms-moderating-role-of-sex-differences-and-a-brain-derived-neurotrophic-factor-gene-polymorphism
#5
Robert L Gabrys, Kaylyn Dixon, Matthew R Holahan, Hymie Anisman
OBJECTIVE: Mild traumatic brain injuries (mTBIs) have frequently been associated with the emergence and persistence of depressive symptoms. However, the factors which contribute to the increased risk for depression after these head injuries remain unclear. Accordingly, we examined the relationship between frequency of self-reported mTBIs and current symptoms of depression and the mediating role of rumination and cognitive flexibility. We also examined whether these relations were moderated by sex differences and the presence of the Val66Met polymorphism in a gene coding for brain-derived neurotrophic factor (BDNF)...
November 21, 2017: Clinical Journal of Sport Medicine: Official Journal of the Canadian Academy of Sport Medicine
https://www.readbyqxmd.com/read/29174830/influence-of-shift-duration-on-cognitive-performance-of-emergency-physicians-a%C3%A2-prospective-cross-sectional-study
#6
Nicolas Persico, François Maltese, Cécile Ferrigno, Amandine Bablon, Cécile Marmillot, Laurent Papazian, Antoine Roch
STUDY OBJECTIVE: The relationship between tiredness and medical errors is now commonly accepted. The main objective of this study is to evaluate the cognitive performance of emergency physicians after a night shift of 14 hours (H14) and after a work shift of 24 hours (H24) and to compare it with tests performed after a rest night at home (H0). METHODS: Forty emergency physicians (19 staff physicians and 21 residents) were randomly evaluated at H0, H14, and H24. Four cognitive abilities (processing speed, working memory capacity, perceptual reasoning, and cognitive flexibility) were tested according to the Wechsler Adult Intelligence Scale and the Wisconsin Card Sorting Test...
November 23, 2017: Annals of Emergency Medicine
https://www.readbyqxmd.com/read/29173201/duration-of-untreated-psychosis-and-neurocognitive-functioning-in-first-episode-psychosis-a-systematic-review-and-meta-analysis
#7
K Allott, D Fraguas, C F Bartholomeusz, C M Díaz-Caneja, C Wannan, E M Parrish, G P Amminger, C Pantelis, C Arango, P D McGorry, M Rapado-Castro
BACKGROUND: Previous reviews suggest there is minimal evidence for an association between duration of untreated psychosis (DUP) and neurocognition. This is based on tallied findings of studies with small samples and neurocognition viewed as a single construct. We aimed to conduct a systematic review and meta-analysis examining the association between DUP and individual neurocognitive domains and tests in first-episode psychosis (FEP). METHOD: MOOSE and PRISMA guidelines were followed...
November 27, 2017: Psychological Medicine
https://www.readbyqxmd.com/read/29136642/common-and-distinct-structural-features-of-schizophrenia-and-bipolar-disorder-the-european-network-on-psychosis-affective-disorders-and-cognitive-trajectory-enpact-study
#8
Eleonora Maggioni, Benedicto Crespo-Facorro, Igor Nenadic, Francesco Benedetti, Christian Gaser, Heinrich Sauer, Roberto Roiz-Santiañez, Sara Poletti, Veronica Marinelli, Marcella Bellani, Cinzia Perlini, Mirella Ruggeri, A Carlo Altamura, Vaibhav A Diwadkar, Paolo Brambilla
INTRODUCTION: Although schizophrenia (SCZ) and bipolar disorder (BD) share elements of pathology, their neural underpinnings are still under investigation. Here, structural Magnetic Resonance Imaging (MRI) data collected from a large sample of BD and SCZ patients and healthy controls (HC) were analyzed in terms of gray matter volume (GMV) using both voxel based morphometry (VBM) and a region of interest (ROI) approach. METHODS: The analysis was conducted on two datasets, Dataset1 (802 subjects: 243 SCZ, 176 BD, 383 HC) and Dataset2, a homogeneous subset of Dataset1 (301 subjects: 107 HC, 85 BD and 109 SCZ)...
2017: PloS One
https://www.readbyqxmd.com/read/29113027/detect-correct-retract-how-to-manage-incorrect-structural-models
#9
REVIEW
Alexander Wlodawer, Zbigniew Dauter, Przemyslaw J Porebski, Wladek Minor, Robyn Stanfield, Mariusz Jaskolski, Edwin Pozharski, Christian X Weichenberger, Bernhard Rupp
The massive technical and computational progress of biomolecular crystallography has generated some adverse side effects. Most crystal structure models, produced by crystallographers or well-trained structural biologists, constitute useful sources of information, but occasional extreme outliers remind us that the process of structure determination is not fail-safe. The occurrence of severe errors or gross misinterpretations raises fundamental questions: Why do such aberrations emerge in the first place? How did they evade the sophisticated validation procedures which often produce clear and dire warnings, and why were severe errors not noticed by the depositors themselves, their supervisors, referees, and editors? Once detected, what can be done to either correct, improve, or eliminate such models? How do incorrect models affect the underlying claims or biomedical hypotheses they were intended, but failed, to support? What is the long-range effect of the propagation of such errors? And finally, what mechanisms can be envisioned to restore the validity of the scientific record and, if necessary, retract publications that are clearly invalidated by the lack of experimental evidence? We suggest that cognitive bias and flawed epistemology are likely at the root of the problem...
November 7, 2017: FEBS Journal
https://www.readbyqxmd.com/read/29045451/getting-to-the-heart-of-the-matter-does-aberrant-interoceptive-processing-contribute-towards-emotional-eating
#10
Hayley A Young, Claire Williams, Aimee E Pink, Gary Freegard, Amy Owens, David Benton
According to estimates from Public Health England, by 2034 70% of adults are expected to be overweight or obese, therefore understanding the underpinning aetiology is a priority. Eating in response to negative affect contributes towards obesity, however, little is known about the underlying mechanisms. Evidence that visceral afferent signals contribute towards the experience of emotion is accumulating rapidly, with the emergence of new influential models of 'active inference'. No longer viewed as a 'bottom up' process, new interoceptive facets based on 'top down' predictions have been proposed, although at present it is unclear which aspects of interoception contribute to aberrant eating behaviour and obesity...
2017: PloS One
https://www.readbyqxmd.com/read/29044765/a-novel-inborn-error-of-the-coenzyme-q10-biosynthesis-pathway-cerebellar-ataxia-and-static-encephalomyopathy-due-to-coq5-c-methyltransferase-deficiency
#11
May Christine V Malicdan, Thierry Vilboux, Bruria Ben-Zeev, Jennifer Guo, Aviva Eliyahu, Ben Pode-Shakked, Amir Dori, Sravan Kakani, Settara C Chandrasekharappa, Carlos R Ferreira, Natalia Shelestovich, Dina Marek-Yagel, Hadass Pri-Chen, Ilan Blatt, John E Niederhuber, Langping He, Camilo Toro, Robert W Taylor, John Deeken, Tal Yardeni, Douglas C Wallace, William A Gahl, Yair Anikster
Primary coenzyme Q10 (CoQ10 ; MIM# 607426) deficiencies are an emerging group of inherited mitochondrial disorders with heterogonous clinical phenotypes. Over a dozen genes are involved in the biosynthesis of CoQ10 , and mutations in several of these are associated with human disease. However, mutations in COQ5 (MIM# 616359), catalyzing the only C-methylation in the CoQ10 synthetic pathway, have not been implicated in human disease. Here, we report three female siblings of Iraqi-Jewish descent, who had varying degrees of cerebellar ataxia, encephalopathy, generalized tonic-clonic seizures, and cognitive disability...
October 16, 2017: Human Mutation
https://www.readbyqxmd.com/read/29021008/medication-review-and-transitions-of-care-a-case-report-of-a-decade-old-medication-error
#12
Rachel Comer, Mitsi Lizer
A 69-year-old Caucasian male with a 25-year history of paranoid schizophrenia was brought to the emergency department because of violence toward the staff in his nursing facility. He was diagnosed with a urinary tract infection and was admitted to the behavioral health unit for medication stabilization. History included a five-year state psychiatric hospital admission and nursing facility placement. Because of poor cognitive function, the patient was unable to corroborate medication history, so the pharmacy student on rotation performed an in-depth chart review...
October 1, 2017: Consultant Pharmacist: the Journal of the American Society of Consultant Pharmacists
https://www.readbyqxmd.com/read/28985112/minimally-sufficient-conditions-for-the-evolution-of-social-learning-and-the-emergence-of-non-genetic-evolutionary-systems
#13
Miguel Gonzalez, Richard Watson, Seth Bullock
Social learning, defined as the imitation of behaviors performed by others, is recognized as a distinctive characteristic in humans and several other animal species. Previous work has claimed that the evolutionary fixation of social learning requires decision-making cognitive abilities that result in transmission bias (e.g., discriminatory imitation) and/or guided variation (e.g., adaptive modification of behaviors through individual learning). Here, we present and analyze a simple agent-based model that demonstrates that the transition from instinctive actuators (i...
2017: Artificial Life
https://www.readbyqxmd.com/read/28981310/dealing-with-interference-chimpanzees-respond-to-conflicting-cues-in-a-food-choice-memory-task
#14
Audrey E Parrish, Anamaria Otalora-Garcia, Michael J Beran
Interference effects emerge when responding on the basis of task-relevant features is directly pitted against task-irrelevant cues that could lead to errors. To study potential interference effects in a food-choice memory test, 3 chimpanzees were presented with conflicting information in a magnitude judgment task. In Experiment 1, chimpanzees were presented with an ordinal series of colored containers that they sequenced on the basis of relative preference for the different foods that were consistently hidden under the containers...
October 2017: Journal of Experimental Psychology. Animal Learning and Cognition
https://www.readbyqxmd.com/read/28977775/the-psychology-of-superorganisms-collective-decision-making-by-insect-societies
#15
Takao Sasaki, Stephen C Pratt
Under the superorganism concept, insect societies are so tightly integrated that they possess features analogous to those of single organisms, including collective cognition. If so, colony function might fruitfully be studied using methods developed to understand individual animals. Here, we review research that uses psychological approaches to understand decision making by colonies. The application of neural models to collective choice shows fundamental similarities between how brains and colonies balance speed/accuracy trade-offs in decision making...
October 4, 2017: Annual Review of Entomology
https://www.readbyqxmd.com/read/28941192/taming-the-zebra-unravelling-the-barriers-to-diagnosing-aortic-dissection
#16
Joe-Anthony Rotella, Michael Yeoh
Aortic dissection is a lethal cardiovascular emergency that continues to pose a diagnostic dilemma to the emergency physician. The condition is rare, can present atypically and is associated with a cumulative mortality for every hour that passes. While it is a recognised differential of acute chest pain, its prevalence in comparison to other causes often leads to the diagnosis being overlooked. The ED is a busy environment with high patient turnover and varying degrees of complexity and acuity. This increases susceptibility to cognitive bias and error-producing conditions that can lead to delayed or missed diagnosis...
September 23, 2017: Emergency Medicine Australasia: EMA
https://www.readbyqxmd.com/read/28903676/the-influence-of-effortful-thought-and-cognitive-proficiencies-on-the-conjunction-fallacy-implications-for-dual-process-theories-of-reasoning-and-judgment
#17
Laura D Scherer, J Frank Yates, S Glenn Baker, Kathrene D Valentine
Human judgment often violates normative standards, and virtually no judgment error has received as much attention as the conjunction fallacy. Judgment errors have historically served as evidence for dual-process theories of reasoning, insofar as these errors are assumed to arise from reliance on a fast and intuitive mental process, and are corrected via effortful deliberative reasoning. In the present research, three experiments tested the notion that conjunction errors are reduced by effortful thought. Predictions based on three different dual-process theory perspectives were tested: lax monitoring, override failure, and the Tripartite Model...
June 2017: Personality & Social Psychology Bulletin
https://www.readbyqxmd.com/read/28901694/the-role-of-cognitive-biases-in-short-term-psychodynamic-psychotherapy
#18
Ueli Kramer, Diana Ortega, Gilles Ambresin, Jean-Nicolas Despland, Yves de Roten
The concept of biased thinking - or cognitive biases - is relevant to psychotherapy research and clinical conceptualization, beyond cognitive theories. The present naturalistic study aimed to examine the changes in biased thinking over the course of a short-term dynamic psychotherapy (STDP) and to discover potential links between these changes and symptomatic improvement. This study focuses on 32 self-referred patients consulting for Adjustment Disorder according to DSM-IV-TR. The therapists were experienced psychodynamically oriented psychiatrists and psychotherapists...
September 13, 2017: Psychology and Psychotherapy
https://www.readbyqxmd.com/read/28860081/clinical-decision-making-heuristics-and-cognitive-biases-for-the-ophthalmologist
#19
REVIEW
Ahsen Hussain, James Oestreicher
Diagnostic errors have a significant impact on health care outcomes and patient care. The underlying causes and development of diagnostic error are complex with flaws in health care systems, as well as human error, playing a role. Cognitive biases and a failure of decision-making shortcuts (heuristics) are human factors that can compromise the diagnostic process. We describe these mechanisms, their role with the clinician, and provide clinical scenarios to highlight the various points at which biases may emerge...
August 30, 2017: Survey of Ophthalmology
https://www.readbyqxmd.com/read/28846445/utilization-of-just-in-time-training-for-nursing-education-using-the-la-phonospirometry-asthma-tool
#20
Kathryn H Pade, Sophia T Seik-Ismail, Todd P Chang, Vincent J Wang
OBJECTIVE: Just-in-time training (JITT) has been used to teach and re-teach known medical techniques, but has not been used to teach novel techniques. We aimed to assess the performance retention of JITT on a novel asthma exacerbation severity assessment technique known as Los Angeles (LA) Phonospirometry. METHODS: This was a prospective cohort study using a convenience sample of pediatric emergency department registered nurses (RNs) who were asked to watch a brief instructional digital video on LA Phonospirometry, and then asked to practice the technique on a research assistant (RA)...
August 28, 2017: Journal of Asthma: Official Journal of the Association for the Care of Asthma
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