keyword
MENU ▼
Read by QxMD icon Read
search

Premature death

keyword
https://www.readbyqxmd.com/read/29910711/functional-consequences-of-the-postnatal-switch-from-neonatal-to-mutant-adult-glycine-receptor-%C3%AE-1-subunits-in-the-shaky-mouse-model-of-startle-disease
#1
Natascha Schaefer, Fang Zheng, Johannes van Brederode, Alexandra Berger, Sophie Leacock, Hiromi Hirata, Christopher J Paige, Robert J Harvey, Christian Alzheimer, Carmen Villmann
Mutations in GlyR α1 or β subunit genes in humans and rodents lead to severe startle disease characterized by rigidity, massive stiffness and excessive startle responses upon unexpected tactile or acoustic stimuli. The recently characterized startle disease mouse mutant shaky carries a missense mutation (Q177K) in the β8-β9 loop within the large extracellular N-terminal domain of the GlyR α1 subunit. This results in a disrupted hydrogen bond network around K177 and faster GlyR decay times. Symptoms in mice start at postnatal day 14 and increase until premature death of homozygous shaky mice around 4-6 weeks after birth...
2018: Frontiers in Molecular Neuroscience
https://www.readbyqxmd.com/read/29907917/neurologic-consequences-of-preterm-birth
#2
REVIEW
Margie A Ream, Lenora Lehwald
PURPOSE OF REVIEW: Preterm birth is the leading cause of death worldwide in children < 5 years of age; however, technology and advances in medical knowledge are increasing the survival of children born even at the fringes of viability. With increased survival comes increased risk of long-term neurologic impairments. This paper aims to review recent findings related to changes in brain development associated with prematurity and its impact on neurodevelopmental disabilities. RECENT FINDINGS: Advanced imaging techniques, longitudinal follow-up of individuals born extremely preterm into adulthood and improved understanding of risk factors associated with neurologic impairment contribute to recent discoveries...
June 16, 2018: Current Neurology and Neuroscience Reports
https://www.readbyqxmd.com/read/29906794/development-of-a-hybrid-course-on-wheelchair-service-provision-for-clinicians-in-international-contexts
#3
Yohali Burrola-Mendez, Mary Goldberg, Rachel Gartz, Jon Pearlman
INTRODUCTION: Wheelchair users worldwide are at high risk of developing secondary health conditions and premature death due to inappropriate wheelchair provision by untrained providers. The International Society of Wheelchair Professionals (ISWP) has developed a Hybrid Course based on the World Health Organization's Wheelchair Service Training Package-Basic Level. The Hybrid Course leverages online modules designed for low-bandwidth internet access that reduces the in-person training exposure from five to three and a half days, making it less expensive and more convenient for both trainees and trainers...
2018: PloS One
https://www.readbyqxmd.com/read/29906699/causes-of-mortality-in-early-infantile-epileptic-encephalopathy-a-systematic-review
#4
REVIEW
Graciane Radaelli, Francisco de Souza Santos, Wyllians Vendramini Borelli, Leonardo Pisani, Magda Lahorgue Nunes, Fulvio Alexandre Scorza, Jaderson Costa da Costa
INTRODUCTION: Early infantile epileptic encephalopathy syndrome (EIEE), also known as Ohtahara syndrome, is an age-dependent epileptic encephalopathy syndrome defined by clinical features and electroencephalographic findings. Epileptic disorders with refractory seizures beginning in the neonatal period and/or early infancy have a potential risk of premature mortality, including sudden death. We aimed to identify the causes of death in EIEE and conducted a literature survey of fatal outcomes...
June 12, 2018: Epilepsy & Behavior: E&B
https://www.readbyqxmd.com/read/29906222/analysis-of-the-microrna-signature-driving-adaptive-right-ventricular-hypertrophy-in-an-ovine-model-of-congenital-heart-disease
#5
Rebecca Johnson Kameny, Youping He, Terry Zhu, Wenhui Gong, Gary W Raff, Cheryl J Chapin, Sanjeev A Datar, Jason Boehme, Akiko Hata, Jeffrey R Fineman
The right ventricular (RV) response to pulmonary arterial hypertension (PAH) is heterogeneous. Most patients have maladaptive changes with RV dilation and failure while some-especially patients with PAH secondary to congenital heart disease (CHD)-have an adaptive response with hypertrophy and preserved systolic function. Mechanisms for RV adaptation to PAH are unknown despite RV function being a primary determinant of mortality. In our CHD ovine model with fetally-implanted aortopulmonary shunt (shunt lambs), we previously demonstrated an adaptive physiologic RV response to increased afterload with hypertrophy...
June 15, 2018: American Journal of Physiology. Heart and Circulatory Physiology
https://www.readbyqxmd.com/read/29902702/ankle-brachial-index-measured-by-oscillometry-is-predictive-for-cardiovascular-disease-and-premature-death-in-the-japanese-population-an-individual-participant-data-meta-analysis
#6
Toshiaki Ohkuma, Toshiharu Ninomiya, Hirofumi Tomiyama, Kazuomi Kario, Satoshi Hoshide, Yoshikuni Kita, Toyoshi Inoguchi, Yasutaka Maeda, Katsuhiko Kohara, Yasuharu Tabara, Motoyuki Nakamura, Takayoshi Ohkubo, Hirotaka Watada, Masanori Munakata, Mitsuru Ohishi, Norihisa Ito, Michinari Nakamura, Tetsuo Shoji, Charalambos Vlachopoulos, Victor Aboyans, Akira Yamashina
BACKGROUND AND AIMS: The ankle-brachial index (ABI) is a predictor of cardiovascular disease (CVD) and premature death. However, few studies on this marker are available in the general Asian populations. This study aimed to investigate the association between ABI measured with oscillometry and the risk of these outcomes. METHODS: We conducted an individual participant data meta-analysis in 10,679 community-dwelling Japanese individuals without a history of CVD. The primary outcome was a composite of CVD events and all-cause mortality...
May 31, 2018: Atherosclerosis
https://www.readbyqxmd.com/read/29902162/youth-risk-behavior-surveillance-united-states-2017
#7
Laura Kann, Tim McManus, William A Harris, Shari L Shanklin, Katherine H Flint, Barbara Queen, Richard Lowry, David Chyen, Lisa Whittle, Jemekia Thornton, Connie Lim, Denise Bradford, Yoshimi Yamakawa, Michelle Leon, Nancy Brener, Kathleen A Ethier
PROBLEM: Health-risk behaviors contribute to the leading causes of morbidity and mortality among youth and adults in the United States. In addition, significant health disparities exist among demographic subgroups of youth defined by sex, race/ethnicity, and grade in school and between sexual minority and nonsexual minority youth. Population-based data on the most important health-related behaviors at the national, state, and local levels can be used to help monitor the effectiveness of public health interventions designed to protect and promote the health of youth at the national, state, and local levels...
June 15, 2018: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/29901839/prophylactic-bypassing-agent-use-before-and-during-immune-tolerance-induction-in-patients-with-haemophilia-a-and-inhibitors-to-fviii
#8
REVIEW
S L Carpenter, K Khair, A Gringeri, L A Valentino
The development of high-titre inhibitory antibodies (inhibitors) against factor VIII (FVIII) remains a challenge in the management of patients with haemophilia A (HA). Patients with high-titre inhibitors are more likely to experience uncontrolled bleeding, physical disability from chronic arthropathy and premature death compared with those without this complication. Immune tolerance induction (ITI), utilizing repeated infusions of FVIII, is an effective therapeutic approach to eliminating inhibitory antibodies...
June 14, 2018: Haemophilia: the Official Journal of the World Federation of Hemophilia
https://www.readbyqxmd.com/read/29901735/contribution-of-chronic-conditions-to-smoking-differences-in-life-expectancy-with-and-without-disability-in-belgium
#9
Renata T C Yokota, Willma J Nusselder, Jean-Marie Robine, Jean Tafforeau, Rana Charafeddine, Lydia Gisle, Patrick Deboosere, Herman Van Oyen
Background: Smoking is the leading cause of premature mortality and morbidity. This study aimed at assessing the impact of smoking on life expectancy (LE) and LE with (LED) and without disability (DFLE). We further estimated the contribution of disability and mortality and their causes to differences in LED and DFLE by smoking. Methods: Data on disability, chronic conditions, and smoking from 17 148 participants of the 1997, 2001, 2004 Belgian Health Interview Surveys were used to estimate causes of disability using the attribution method...
June 12, 2018: European Journal of Public Health
https://www.readbyqxmd.com/read/29900612/prevalence-antenatal-management-and-perinatal-outcomes-of-monochorionic-monoamniotic-twin-pregnancies-a-collaborative-multicentre-study-in-england-2000-2013
#10
Svetlana V Glinianaia, Judith Rankin, Asma Khalil, Julia Binder, Gareth Waring, Stephen N Sturgiss, Basky Thilaganathan, Therese Hannon
OBJECTIVES: To determine the prevalence of monochorionic monoamniotic (MCMA) twin pregnancies and to describe perinatal outcomes and clinical management of these pregnancies. METHODS: This multicentre cohort study used population-based data on MCMA twin pregnancies from 11 Northern Survey of Twin and Multiple Pregnancy (NorSTAMP) maternity units for the prevalence estimation of MCMA twinning. Pregnancy outcomes at <24 weeks' gestation, antenatal parameters and perinatal outcomes (from ≥24 weeks to the first 28 days of life) were analysed using combined data on pregnancies with confirmed MCMA chorionicity from the NorSTAMP and the Southwest Thames Region of London Obstetric Research Collaborative (STORK) multiple pregnancy cohort for 2000-2013...
June 13, 2018: Ultrasound in Obstetrics & Gynecology
https://www.readbyqxmd.com/read/29896912/exposure-to-household-air-pollution-from-biomass-burning-cookstoves-and-hba1c-and-diabetic-status-among-honduran-women
#11
Sarah Rajkumar, Maggie L Clark, Bonnie N Young, Megan L Benka-Coker, Annette M Bachand, Robert D Brook, Tracy L Nelson, John Volckens, Stephen J Reynolds, Christian L'Orange, Nicholas Good, Kirsten Koehler, Sebastian Africano, Anibal B Osorto Pinel, Jennifer L Peel
Household air pollution from biomass cookstoves is estimated to be responsible for more than two and a half million premature deaths annually, primarily in low and middle-income countries where cardiometabolic disorders, such as Type II Diabetes, are increasing. Growing evidence supports a link between ambient air pollution and diabetes, but evidence for household air pollution is limited. This cross-sectional study of 142 women (72 with traditional stoves and 70 with cleaner-burning Justa stoves) in rural Honduras evaluated the association of exposure to household air pollution (stove type, 24-hour average kitchen and personal fine particulate matter [PM2...
June 13, 2018: Indoor Air
https://www.readbyqxmd.com/read/29896844/effects-of-6-months-supervised-physical-training-on-muscle-strength-and-aerobic-capacity-in-patients-undergoing-roux-en-y-gastric-bypass-surgery-a-randomized-controlled-trial
#12
L H Mundbjerg, C R Stolberg, E-M Bladbjerg, P Funch-Jensen, C B Juhl, B Gram
Obesity and physical inactivity are major health problems. Roux-en-Y gastric bypass (RYGB) surgery results in significant weight loss and reduces obesity-related morbidity and mortality. Physical activity lowers the risk of cardiovascular disease and premature death. The aims of this study were to elucidate the effects of RYGB followed by 6 months of supervised physical training on physical capacity. In a randomized controlled trial, 60 participants eligible for RYGB were randomized 6 months post-surgery to either two weekly physical training sessions for 26 weeks (INT) or a control group (CON)...
June 12, 2018: Clinical Obesity
https://www.readbyqxmd.com/read/29895759/classical-risk-factors-and-inflammatory-biomarkers-one-of-the-missing-biological-links-between-cardiovascular-disease-and-major-depressive-disorder
#13
Thomas C Baghai, Gabriella Varallo-Bedarida, Christoph Born, Sibylle Häfner, Cornelius Schüle, Daniela Eser, Peter Zill, André Manook, Johannes Weigl, Somayeh Jooyandeh, Caroline Nothdurfter, Clemens von Schacky, Brigitta Bondy, Rainer Rupprecht
BACKGROUND: Cardiovascular disorders (CVD) and major depressive disorder (MDD) are the most frequent diseases worldwide responsible for premature death and disability. Behavioral and immunological variables influence the pathophysiology of both disorders. We therefore determined frequency and severity of MDD in CVD and studied whether MDD without CVD or other somatic diseases influences classical and inflammatory biomarkers of cardiovascular risk. In addition, we investigated the influence of proinflammatory cytokines on antidepressant treatment outcome...
June 12, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29892007/familial-hypercholesterolemia-in-very-young-myocardial-infarction
#14
Sha Li, Hui-Wen Zhang, Yuan-Lin Guo, Na-Qiong Wu, Cheng-Gang Zhu, Xi Zhao, Di Sun, Xiong-Yi Gao, Ying Gao, Yan Zhang, Ping Qing, Xiao-Lin Li, Jing Sun, Geng Liu, Qian Dong, Rui-Xia Xu, Chuan-Jue Cui, Jian-Jun Li
Familial hypercholesterolemia (FH) is one of the most common causes of premature myocardial infarction (MI). However, The patterns of FH remained unrecognized in clinical care, especially in very young patients (VYPs, ≤35 years) with MI. The present study enrolled a total of 1,093 VYPs (≤35 years) presenting a first MI. Clinical diagnosis of FH was made using Dutch Lipid Clinic Network criteria. Coronary severity was assessed by Gensini score (GS). Patients were followed for a median of 40-months with cardiac death, stroke, MI, post-discharge revascularization or unstable angina as primary endpoints...
June 11, 2018: Scientific Reports
https://www.readbyqxmd.com/read/29891795/prevalence-of-smoking-among-men-in-ethiopia-and-kenya-a-cross-sectional-study
#15
Shangfeng Tang, Ghose Bishwajit, Tegene Regassa Luba, Sanni Yaya
While tobacco use remains the largest single cause of premature death in the industrialized countries, low-and-middle income countries are also experiencing a rising burden of the tobacco epidemic and are making various programmatic efforts to tackle the issue. Evidence-based policy making is critical to the long-term success of tobacco intervention programs and is reliant on regular monitoring of the trends and prevalence rates of tobacco use though population-based surveys, which are sparse for countries in eastern Africa...
June 11, 2018: International Journal of Environmental Research and Public Health
https://www.readbyqxmd.com/read/29890937/cardiovascular-disease-and-high-blood-pressure-trend-analyses-from-2002-to-2016-after-the-implementation-of-a-salt-reduction-strategy
#16
D Abreu, P Sousa, C Matias-Dias, F J Pinto
BACKGROUND: Cardiovascular disease (CVD) is the leading cause of death around the world; however, many CVD events could be prevented if we focused on modification of the main risk factors. Increased salt consumption is estimated to have caused millions of deaths, mostly related to CVD, particularly stroke, which is the leading cause of death in Portugal. In our study, we aim to assess trends in the proportion of high blood pressure (HBP) in Acute Coronary Syndrome (ACS) patients as well as the trends in stroke and ACS in Portugal, especially after a set of public health initiatives were implemented to reduce salt intake...
June 11, 2018: BMC Public Health
https://www.readbyqxmd.com/read/29889687/associations-of-source-apportioned-fine-particles-with-cause-specific-mortality-in-california
#17
Kimberly Berger, Brian J Malig, Sina Hasheminassab, Dharshani L Pearson, Constantinos Sioutas, Bart Ostro, Rupa Basu
BACKGROUND: Exposure to ambient fine particulate matter (PM2.5) has been linked with premature mortality, but sources of PM2.5 have been less studied. METHODS: We evaluated associations between source-specific PM2.5 exposures and cause-specific short-term mortality in eight California locations from 2002-2011. Speciated PM2.5 measurements were source-apportioned using Positive Matrix Factorization into eight sources and combined with death certificate data. We utilized time-stratified case-crossover analysis with conditional logistic regression by location, and meta-analysis to calculate pooled estimates...
June 6, 2018: Epidemiology
https://www.readbyqxmd.com/read/29886805/psychosocial-and-biological-paternal-role-in-pregnancy-outcomes
#18
Maryam Kashanian, Masoomeh Faghankhani, Hasti Hadizadeh, MMasoud Salehi, Masoomeh YousefzadehRoshan, Mohammad EhsaniPour, Ladan Sayyah, Narges Sheikhansari
BACKGROUND: Pregnancy outcomes are affected by many different factors. One of the influential factors on pregnancy outcomes is the male partner as an important person to mother's wellbeing. OBJECTIVE: The aim of the present study was to investigate the effects of male partner's role including socioeconomic support, emotional support, accompanying pregnant women during prenatal care visits (PNC) and labor, and the level of pregnant women's satisfaction from their partners' support and involvement during pregnancy on pregnancy outcomes...
June 10, 2018: Journal of Maternal-fetal & Neonatal Medicine
https://www.readbyqxmd.com/read/29886248/little-cigars-and-cigarillos-affect-and-perceived-relative-harm-among-u-s-adults-2015
#19
Ban A Majeed, Amy Nyman, Kymberle L Sterling, Paul Slovic
INTRODUCTION: Similar to cigarette smoking, consumption of cigars delivers nicotine and byproducts of tobacco combustion and elevates the risk of addiction, illness, and premature death. This study examined the relationship of affect, perceived relative harm, and LCC smoking behavior among U.S. adults. METHODS: Data were from Tobacco Products and Risk Perceptions Survey conducted in 2015. The study included a probability based sample of 6051 adults (18+) drawn from an online research panel...
May 25, 2018: Addictive Behaviors
https://www.readbyqxmd.com/read/29885776/early-energy-and-protein-intakes-and-associations-with-growth-bpd-and-rop-in-extremely-preterm-infants
#20
Susanna Klevebro, Vera Westin, Elisabeth Stoltz Sjöström, Mikael Norman, Magnus Domellöf, Anna-Karin Edstedt Bonamy, Boubou Hallberg
BACKGROUND & AIM: Extremely preterm infants face substantial neonatal morbidity. Nutrition is important to promote optimal growth and organ development in order to reduce late neonatal complications. The aim of this study was to examine the associations of early nutritional intakes on growth and risks of bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) in a high-risk population. METHODS: This population-based cohort study includes infants born before 27 0/7 weeks of gestational age without severe malformations and surviving ≥10 days...
May 29, 2018: Clinical Nutrition: Official Journal of the European Society of Parenteral and Enteral Nutrition
keyword
keyword
63894
1
2
Fetch more papers »
Fetching more papers... Fetching...
Read by QxMD. Sign in or create an account to discover new knowledge that matter to you.
Remove bar
Read by QxMD icon Read
×

Search Tips

Use Boolean operators: AND/OR

diabetic AND foot
diabetes OR diabetic

Exclude a word using the 'minus' sign

Virchow -triad

Use Parentheses

water AND (cup OR glass)

Add an asterisk (*) at end of a word to include word stems

Neuro* will search for Neurology, Neuroscientist, Neurological, and so on

Use quotes to search for an exact phrase

"primary prevention of cancer"
(heart or cardiac or cardio*) AND arrest -"American Heart Association"