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Quality of life measurement

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https://www.readbyqxmd.com/read/28813183/quality-of-life-in-children-with-orofacial-clefts-and-caregiver-well-being
#1
L Sischo, M Wilson-Genderson, H L Broder
Quality of life is a valid patient-reported parameter that provides an assessment of treatment need or outcomes complementary to standard clinical measures. Such patient-reported assessments are particularly salient when examining chronic conditions with prolonged treatment trajectories, such as cleft lip and palate. This critical review identifies key questions related to ongoing research on the oral health-related quality of life (OHRQoL) in children with cleft and caregiver well-being. Details of the design and results from 2 longitudinal multicenter studies are presented...
August 1, 2017: Journal of Dental Research
https://www.readbyqxmd.com/read/28813080/the-relationship-between-motor-function-cognition-independence-and-quality-of-life-in-myelomeningocele-patients
#2
Carolina Lundberg Luz, Maria Clara Drummond Soares de Moura, Karine Kyomi Becker, Rosani Aparecida Antunes Teixeira, Mariana Callil Voos, Renata Hydee Hasue
Motor function, cognition, functional independence and quality of life have been described in myelomeningocele patients, but no study has investigated their relationships. We aimed to investigate the relationships between motor function, cognition, functional independence, quality of life, age, and lesion level in myelomeningocele patients, and investigate the influence of hydrocephalus on these variables. We assessed 47 patients with the Gross Motor Function Measure (motor function), Raven's Colored Progressive Matrices (cognition), Pediatric Evaluation of Disability Inventory (functional independence) and the Autoquestionnaire Qualité de vie Enfant Imagé (quality of life)...
August 2017: Arquivos de Neuro-psiquiatria
https://www.readbyqxmd.com/read/28813073/functional-health-literacy-and-quality-of-life-of-high-school-adolescents-in-state-schools-in-belo-horizonte
#3
Poliana Cristina Rocha, Dálian Cristina Rocha, Stela Maris Aguiar Lemos
Purpose: To investigate the association between functional health literacy and sociodemographic factors, quality of life, self-perception of health, and perception of contexts of violence in adolescents in state schools in Belo Horizonte. Methods: This is a cross-sectional analytical observational study with a probabilistic sample of 384 adolescents between 15 and 19 years old. Data collection was carried out in schools and included self-reporting questionnaires to assess the functional health literacy, socioeconomic classification, self-perceived health, and quality of life...
August 10, 2017: CoDAS
https://www.readbyqxmd.com/read/28812375/the-family-caregiver-experience%C3%A2-%C3%A2-examining-the-positive-and-negative-aspects-of-compassion-satisfaction-and-compassion-fatigue-as-caregiving-outcomes
#4
Susan H Lynch, Geoff Shuster, Marie L Lobo
OBJECTIVES: Caregiving results in both positive and negative outcomes for caregivers. The purpose of this study was to examine compassion fatigue and compassion satisfaction in family caregivers. METHODS: Using a cross sectional descriptive survey design with a convenience sample, 168 family caregivers of individuals with chronic illness completed a web-based survey. Measures included a demographic questionnaire, Caregiver Burden Interview, Brief COPE inventory and Professional Quality of Life (ProQOL)...
August 16, 2017: Aging & Mental Health
https://www.readbyqxmd.com/read/28812175/a-prospective-non-randomized-controlled-multicenter-trial-comparing-appendectomy-and-conservative-treatment-for-patients-with-uncomplicated-acute-appendicitis-the-actuaa-study
#5
Mauro Podda, Fernando Serventi, Lorenzo Mortola, Stefano Marini, Danilo Sirigu, Michela Piga, Marcello Pisano, Massimiliano Coppola, Ferdinando Agresta, Francesco Virdis, Salomone Di Saverio, Nicola Cillara
PURPOSE: Acute appendicitis (AA) is among the most common causes of lower abdominal pain and admissions to the emergency department. Over the past 20 years, there has been a renewed interest in the conservative management of uncomplicated AA, and several studies demonstrated that an antibiotic-first strategy is a viable treatment option for uncomplicated AA. The aim of this prospective non-randomized controlled, multicenter trial is to compare antibiotic therapy and emergency appendectomy as treatment for patients with uncomplicated AA confirmed by US and/or CT or MRI scan...
August 15, 2017: International Journal of Colorectal Disease
https://www.readbyqxmd.com/read/28811262/probe-microscopy-methods-and-applications-in-imaging-of-biological-materials
#6
REVIEW
Alper D Ozkan, Ahmet E Topal, Fatma B Dikecoglu, Mustafa O Guler, Aykutlu Dana, Ayse B Tekinay
Atomic force microscopy is an emerging tool for investigating the biomolecular aspects of cellular interactions; however, cell and tissue analyses must frequently be performed in aqueous environment, over rough surfaces, and on complex adhesive samples that complicate the imaging process and readily facilitate the blunting or fouling of the AFM probe. In addition, the shape and surface chemistry of the probe determine the quality and types of data that can be acquired from biological materials, with certain information becoming available only within a specific range of tip lengths or diameters, or through the assistance of specific chemical or biological functionalization procedures...
August 12, 2017: Seminars in Cell & Developmental Biology
https://www.readbyqxmd.com/read/28811227/the-chemotherapeutic-agent-paclitaxel-selectively-impairs-reversal-learning-while-sparing-prior-learning-new-learning-and-episodic-memory
#7
Danielle Panoz-Brown, Lawrence M Carey, Alexandra E Smith, Meredith Gentry, Christina M Sluka, Hannah E Corbin, Jie-En Wu, Andrea G Hohmann, Jonathon D Crystal
Chemotherapy is widely used to treat patients with systemic cancer. The efficacy of cancer therapies is frequently undermined by adverse side effects that have a negative impact on the quality of life of cancer survivors. Cancer patients who receive chemotherapy often experience chemotherapy-induced cognitive impairment across a variety of domains including memory, learning, and attention. In the current study, the impact of paclitaxel, a taxane derived chemotherapeutic agent, on episodic memory, prior learning, new learning, and reversal learning were evaluated in rats...
August 12, 2017: Neurobiology of Learning and Memory
https://www.readbyqxmd.com/read/28811155/assessing-changes-in-quality-of-life-and-independent-living-and-working-levels-among-agrability-farmers-and-ranchers-with-disabilities
#8
Robert J Fetsch, Danielle M Jackman, Christina L Collins
BACKGROUND: While emerging research has focused on quality of life (QOL) levels among farmers and ranchers with disabilities, much work is still needed on this largely understudied population. The AgrAbility Project, a USDA initiative, offers pragmatic solutions to increase farmers and ranchers with disabilities' QOL and ability to work and live independently (ILW). OBJECTIVES: To assess pretest-posttest changes in farmers and ranchers with disabilities' ILW and QOL levels after participating in AgrAbility, to identify demographic predictors of ILW and QOL (e...
August 8, 2017: Disability and Health Journal
https://www.readbyqxmd.com/read/28810990/gait-and-functional-outcomes-for-young-active-males-with-traumatic-unilateral-transfemoral-limb-loss
#9
Caitlin E Mahon, Alison L Pruziner, Brad D Hendershot, Erik J Wolf, Benjamin J Darter, K Bo Foreman, Joseph B Webster
OBJECTIVE: Altered body structures that occur with the loss of a lower limb can impact mobility and quality of life. Specifically, biomechanical changes that result from wearing a prosthesis have been associated with an increased risk of falls or joint degeneration, as well as increased energy demands. While previous studies describing these outcomes are typically limited by number of outcome measures and/or small, diverse patient groups, recent military conflicts present a unique opportunity to collect outcomes from a relatively homogenous, active patient population with limb loss...
July 2017: Military Medicine
https://www.readbyqxmd.com/read/28810915/quality-of-life-and-correlation-with-clinical-and-radiographic-variables-in-patients-with-ankylosing-spondylitis-a-retrospective-case-series-study
#10
Ji-Chen Huang, Bang-Ping Qian, Yong Qiu, Bin Wang, Yang Yu, Ze-Zhang Zhu, Jun Hu, Zhe Qu
BACKGROUND: Previously, many studies have evaluated quality of life (QoL) in patients with ankylosing spondylitis (AS), however, none of them specifically investigated the correlation between pain-related disability measured by Oswestry Disability Index (ODI) and QoL in AS patients. In addition, the correlation between global kyphosis (GK) in lateral plain radiographs and QoL in AS patients remains unclear up to now. Therefore, this study aimed to evaluate QoL and correlation with clinical and radiographic variables in AS patients, especially to figure out the relationship about the pain-specific disability measured by ODI, GK and QoL...
August 15, 2017: BMC Musculoskeletal Disorders
https://www.readbyqxmd.com/read/28810405/a-case-control-study-of-psychosocial-factors-and-their-relationship-to-impairment-and-functionality-in-multiple-sclerosis
#11
Laia Briones-Buixassa, Raimon Milà, Francesc X Arrufat, Josep Mª Aragonès, Enric Bufill, Olivier Luminet, Rona Moss-Morris
The stress effect on multiple sclerosis remains unclear. Moderating psychosocial factors may be involved. This study compares some of them in people with multiple sclerosis and healthy controls, and their association with disease parameters. Coping style, social support, anxiety, alexithymia and early-life stress were measured, along with impairment and functionality. People with multiple sclerosis scored significantly higher on anxiety, alexithymia, and avoidance and instinctive coping but lower in social support...
February 1, 2017: Journal of Health Psychology
https://www.readbyqxmd.com/read/28809994/the-static-physician-s-global-assessment-of-genitalia-a-clinical-outcome-measure-for-the-severity-of-genital-psoriasis
#12
Joseph F Merola, Alison Potts Bleakman, Alice B Gottlieb, Alan Menter, April N Naegeli, Robert Bissonnette, Lyn Guenther, John Sullivan, Kim Meeuwis, Kyoungah See, Kristina Callis Duffin
<p>Introduction: Genital psoriasis is a common but frequently overlooked manifestation of psoriasis with a considerable impact on patients' quality of life. Currently no validated clinical trial outcome measures exist to assess genital psoriasis severity that meet regulatory agency requirements.</p> <p>Methods: This study describes the development of the static Physician's Global Assessment of Genitalia (sPGA-G) scale, a clinical outcome measure for the assessment of genital psoriasis severity that accounts for the erythematous clinical presentation of genital psoriasis...
August 1, 2017: Journal of Drugs in Dermatology: JDD
https://www.readbyqxmd.com/read/28809640/-treatment-of-displaced-patellar-fractures-with-multiple-circular-cerclage
#13
Z Tříska, J Urban, P Látal, M Kloub
PURPOSE OF THE STUDY The study aims to conduct a mid-term evaluation of results of the treatment of patellar fractures with multiple circular cerclage. MATERIAL AND METHODS The retrospective clinical study with its own group of patients who underwent surgery in our centre in the period from 2008 to 2014. The study included a total of 29 patients with displaced patellar fractures treated with multiple circular cerclage. The available radiographic documentation was assessed and the quality of perioperative reposition, fracture healing, loss of reposition and potential failure of osteosynthesis material was considered...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28809624/spinal-orthoses-the-crucial-role-of-comfort-on-compliance-of-wearing-monocentric-prospective-pilot-study-of-randomized-cross-over-design
#14
G W Herget, S Patermann, P C Strohm, J Zwingmann, P Eichelberger, N P Südkamp, A Hirschmüller
PURPOSE OF THE STUDY Various spine disorders are regularly treated by orthoses, and success of treatment depends on wearing these devices. In this study we examined the compliance, wear comfort, subjective stabilization and side effects associated with spinal orthoses using an individualized questionnaire and the Compact Short Form-12 Health Survey (SF-12). MATERIAL AND METHODS In this prospective pilot study of randomized cross-over design, twelve healthy volunteers with a mean age of 31.2 years wore three different types of orthoses, each for one week: A hyperextension brace (HB), a custom-made semirigid orthosis (SO) and a custom-made rigid orthosis (RO)...
2017: Acta Chirurgiae Orthopaedicae et Traumatologiae Cechoslovaca
https://www.readbyqxmd.com/read/28809610/phase-iii-study-comparing-a-reduced-dose-of-cabazitaxel-20-mg-m-2-and-the-currently-approved-dose-25-mg-m-2-in-postdocetaxel-patients-with-metastatic-castration-resistant-prostate-cancer-proselica
#15
Mario Eisenberger, Anne-Claire Hardy-Bessard, Choung Soo Kim, Lajos Géczi, Daniel Ford, Loïc Mourey, Joan Carles, Phillip Parente, Albert Font, Gabriel Kacso, Mustapha Chadjaa, Wenping Zhang, John Bernard, Johann de Bono
Purpose Cabazitaxel 25 mg/m(2) (C25) significantly improved overall survival (OS) versus mitoxantrone ( P < .001) in postdocetaxel patients with metastatic castration-resistant prostate cancer (mCRPC) in the phase III TROPIC study. The phase III PROSELICA study ( ClinicalTrials.gov identifier: NCT01308580) assessed the noninferiority of cabazitaxel 20 mg/m(2) (C20) versus C25 in postdocetaxel patients with mCRPC. Methods Patients were stratified by Eastern Cooperative Oncology Group performance status, measurability of disease per Response Evaluation Criteria in Solid Tumors (RECIST), and region, and randomly assigned to receive C20 or C25...
August 15, 2017: Journal of Clinical Oncology: Official Journal of the American Society of Clinical Oncology
https://www.readbyqxmd.com/read/28809377/health-related-quality-of-life-of-patients-with-zygomatic-fracture
#16
L Kaukola, J Snäll, R Roine, H Sintonen, H Thorén
BACKGROUND: The objective was to evaluate health-related quality of life (HRQoL) before and after surgical treatment of zygomatic complex fracture and assess patients' perceptions of the aesthetic and functional outcomes of surgery. MATERIAL AND METHODS: A prospective study of 79 adult patients before and after surgery for zygomatic complex fracture was conducted. HRQoL was measured using the generic 15-dimensional (15D) instrument, and patient satisfaction was assessed by an additional questionnaire...
August 15, 2017: Medicina Oral, Patología Oral y Cirugía Bucal
https://www.readbyqxmd.com/read/28809175/the-use-of-data-analytics-to-build-an-australian-context-sensitive-health-informatics-framework-for-consumer-directed-community-aged-care
#17
Andrew Georgiou, Mikaela Jorgensen, Joyce Siette, Johanna I Westbrook
The challenge of providing services that meet the growing needs of an ageing population is one confronted by communities across Australia and internationally. The aim of this study was to: a) undertake semi-structured interviews and focus groups across a sample of service and technical staff to identify the interconnection between communication, information, work practices and performance; and b) carry out a comprehensive review of existing data sources to identify the data linkages required to identify and monitor performance across different dimensions of the quality of aged care spectrum...
2017: Studies in Health Technology and Informatics
https://www.readbyqxmd.com/read/28808982/radial-head-prosthesis-results-overview
#18
E Carità, A Donadelli, L Cugola, P Perazzini
BACKGROUND/PURPOSE: Radial head replacement is frequently used in treatment of radial head fractures or sequela. Impossibility to restore a correct anatomy, acute elbow traumatic instability and failure of osteosynthesis hardware are the most common indications. The authors describe their case studies and results on the implantation of various radial head prostheses. MATERIALS: Between June 2005 and June 2016, 28 radial head prostheses were implanted in the same number of patients with an average follow-up of 49 months (6-104)...
August 14, 2017: Musculoskeletal Surgery
https://www.readbyqxmd.com/read/28808777/phase-ii-study-of-bi-weekly-temozolomide-plus-bevacizumab-for-adult-patients-with-recurrent-glioblastoma
#19
Michael A Badruddoja, Marjorie Pazzi, Abhay Sanan, Kurt Schroeder, Kevin Kuzma, Thomas Norton, Thomas Scully, Daruka Mahadevan, Michael Malek Ahmadi
PURPOSE: Bevacizumab is an active anti-angiogenic agent in the treatment of recurrent glioblastoma. Temozolomide can prolong survival in patients with newly diagnosed glioblastoma. At recurrence, alternate dosing of temozolomide has shown to further deplete methyl-guanine-methyltransferase (MGMT) conferring added activity for patients who have progressed on the standard dosing regimen. In this study, bevacizumab plus biweekly temozolomide was evaluated for efficacy in adult patients with recurrent glioblastoma...
August 14, 2017: Cancer Chemotherapy and Pharmacology
https://www.readbyqxmd.com/read/28807845/1-hz-rtms-in-the-treatment-of-tinnitus-a-sham-controlled-randomized-multicenter-trial
#20
Michael Landgrebe, Göran Hajak, Stefan Wolf, Frank Padberg, Philipp Klupp, Andreas J Fallgatter, Thomas Polak, Jacqueline Höppner, Rene Haker, Joachim Cordes, Thomas Klenzner, Carlos Schönfeldt-Lecuona, Thomas Kammer, Erika Graf, Michael Koller, Tobias Kleinjung, Astrid Lehner, Martin Schecklmann, Timm B Pöppl, Peter Kreuzer, Elmar Frank, Berthold Langguth
BACKGROUND: Chronic tinnitus is a frequent, difficult to treat disease with high morbidity. OBJECTIVE: This multicenter randomized, sham-controlled trial investigated the efficacy and safety of 1-Hz repetitive transcranial magnetic stimulation (rTMS) applied to the left temporal cortex in patients with chronic tinnitus. METHODS: Tinnitus patients were randomized to receive 10 sessions of either real or sham 1-Hz-rTMS (2000 stimuli, 110% motor threshold) to the left temporal cortex...
August 5, 2017: Brain Stimulation
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