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https://www.readbyqxmd.com/read/28531118/the-venom-repertoire-of-conus-gloriamaris-chemnitz-1777-the-glory-of-the-sea
#1
Samuel D Robinson, Qing Li, Aiping Lu, Pradip K Bandyopadhyay, Mark Yandell, Baldomero M Olivera, Helena Safavi-Hemami
The marine cone snail Conus gloriamaris is an iconic species. For over two centuries, its shell was one of the most prized and valuable natural history objects in the world. Today, cone snails have attracted attention for their remarkable venom components. Many conotoxins are proving valuable as research tools, drug leads, and drugs. In this article, we present the venom gland transcriptome of C. gloriamaris, revealing this species' conotoxin repertoire. More than 100 conotoxin sequences were identified, representing a valuable resource for future drug discovery efforts...
May 20, 2017: Marine Drugs
https://www.readbyqxmd.com/read/28530432/posttraumatic-stress-symptom-severity-and-health-service-utilization-in-trauma-exposed-parents
#2
Emma J Thompson, Vicki A Anderson, Stephen J C Hearps, Maria C McCarthy, Cathrine Mihalopoulos, Jan M Nicholson, Meredith Rayner, Frank Muscara
OBJECTIVE: Posttraumatic stress disorder (PTSD) and posttraumatic stress symptoms (PTSSs) are common for parents of children with life-threatening illnesses or injuries. The impact of these psychological sequelae on parents' personal use of health services is unknown. The present study aimed to investigate whether PTSS severity prospectively predicts increased health service utilization (HSU), and to examine the relative importance of other predisposing and enabling factors in predicting HSU...
May 22, 2017: Health Psychology: Official Journal of the Division of Health Psychology, American Psychological Association
https://www.readbyqxmd.com/read/28530082/-cervical-cancer-in-israel-2016-facts-insights-and-thoughts-for-the-future
#3
REVIEW
Menahem Fisher, Eduardo Schejter, Ido Solt, Gad Renart
The natural history of precancerous lesions and cervical cancer in Israeli women differs from that reported in the world. In 2011, 244 women were diagnosed in Israel with invasive cervical cancer, with the mortality of 79 women. The incidence of cervical cancer in Israel is about 5 new cases per year per 100,000 women (5.4 Jewish, 3.2 Arab). This figure is very low compared with statistics presented in other countries and has not changed over the last decades. The vast majority of Israeli women were diagnosed due to symptoms and not following Pap smear screening...
September 2016: Harefuah
https://www.readbyqxmd.com/read/28530047/what-is-it-going-to-take-to-move-youth-related-hiv-programme-policies-into-practice-in-africa
#4
Daniella Mark, Lina Taing, Lucie Cluver, Chris Collins, Kate Iorpenda, Catarina Andrade, Luann Hatane
INTRODUCTION: HIV has been reported to be the leading cause of mortality amongst adolescents in Africa. This has brought attention to the changes in service provision and health management that many adolescents living with HIV experience when transferring from specialized paediatric- or adolescent-focused services to adult care. When transition is enacted poorly, adherence may be affected and the continuum of care disrupted. As the population of HIV-infected adolescents grows, effective and supported transition increases in significance as an operational imperative...
May 16, 2017: Journal of the International AIDS Society
https://www.readbyqxmd.com/read/28529113/integrating-natural-language-processing-expertise-with-patient-safety-event-review-committees-to-improve-the-analysis-of-medication-events
#5
Allan Fong, Nicole Harriott, Donna M Walters, Hanan Foley, Richard Morrissey, Raj R Ratwani
OBJECTIVES: Many healthcare providers have implemented patient safety event reporting systems to better understand and improve patient safety. Reviewing and analyzing these reports is often time consuming and resource intensive because of both the quantity of reports and length of free-text descriptions in the reports. METHODS: Natural language processing (NLP) experts collaborated with clinical experts on a patient safety committee to assist in the identification and analysis of medication related patient safety events...
May 11, 2017: International Journal of Medical Informatics
https://www.readbyqxmd.com/read/28528949/synthesis-and-characterization-of-cellulose-silver-nanocomposites-from-bioflocculant-reducing-agent
#6
L Muthulakshmi, N Rajini, A Varada Rajalu, Suchart Siengchin, T Kathiresan
Microbial secreted polymers have high molecular weight due to the presence of repeated units of macromolecules. Some of the polymers are derived from natural resources, including marine and soil microorganisms. In nano-biotechnology people are using different biological agents in the preparation of metal nanoparticles. In this study, the microbial bioflocculant polymer was used as an agent in preparation of silver nanoparticles. The prepared nanoparticles were immobilized into the cellulose matrix. The presence of silver nanoparticles inside the cellulose matrix was confirmed by Scanning Electron Microscopic (SEM) and Transmission Electron Microscopic (TEM) analyses...
May 18, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28528408/the-glaucous-winged-gull-larus-glaucescens-as-an-indicator-of-chemical-contaminants-in-the-canadian-pacific-marine-environment-evidence-from-stable-isotopes
#7
M L Davis, J E Elliott, T D Williams
The Glaucous-winged gull (Larus glaucescens) has been selected by Environment Canada as a marine indicator species for long-term monitoring of persistent contaminants in the Canadian Pacific. However, the indicator value of this species depends on its trophic level and proportion of marine prey in its diet. Eggs, used as the monitoring medium, are produced entirely from maternal resources and knowledge of adult diet before and during egg production is critical to interpreting contaminant levels. Due to a lack of recent and reliable dietary ecology work, we examined the diet of breeding Glaucous-winged gulls through carbon (δ(13)C) and nitrogen (δ(15)N) stable isotope analysis at three colonies on the Pacific coast...
May 20, 2017: Archives of Environmental Contamination and Toxicology
https://www.readbyqxmd.com/read/28527741/reeling-in-the-damages-harmful-algal-blooms-impact-on-lake-erie-s-recreational-fishing-industry
#8
David Wolf, Will Georgic, H Allen Klaiber
Lake Erie is one of the most valuable natural resources in the United States, providing billions of dollars in benefits each year to recreationalists, homeowners and local governments. The ecosystem services provided by Lake Erie, however, are under threat due to harmful algal blooms. This paper provides recreational damage estimates using spatially and temporally varying algae measures and monthly fishing permit sales collected between 2011 and 2014. Results indicate that fishing license sales drop between 10% and 13% when algal conditions surpass the World Health's Organization's moderate health risk advisory threshold of 20,000 cyanobacteria cells/mL...
May 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28527739/local-people-s-knowledge-with-regard-to-land-use-activities-in-southwest-madagascar-conceptual-insights-for-sustainable-land-management
#9
Nadine V M Fritz-Vietta, H Stone Tahirindraza, Susanne Stoll-Kleemann
Environmental conditions in the Mahafaly Plateau region in southwest Madagascar are harsh, with a long dry season and a short rainy season. The local people's land use capabilities and skills are adapted to these conditions. Nevertheless, they are currently confronted by drastic climatic changes, including longer dry seasons, which have resulted in food and water scarcities. It is therefore essential to ensure sustainable land management in the region. At present, the main land use activities are agriculture, livestock farming, natural resource collection including timber and non-timber forest products, and the practice of local customs...
May 18, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28527379/diagnosing-water-security-in-the-rural-north-with-an-environmental-security-framework
#10
Henry J F Penn, Philip A Loring, William E Schnabel
This study explores the nature of water security challenges in rural Alaska, using a framework for environmental security that entails four interrelated concepts: availability, access, utility, and stability of water resources. Many researchers and professionals agree that water insecurity is a problem in rural Alaska, although the scale and nature of the problem is contested. Some academics have argued that the problem is systemic, and rooted in an approach to water security by the state that prioritizes economic concerns over public health concerns...
May 17, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28527377/fishing-for-leadership-the-role-diversification-plays-in-facilitating-change-agents
#11
Joshua S Stoll
Leadership is often viewed as being critical to successful natural resource management. This research focuses on a set of leaders identified through a social network analysis of fishers in a rural coastal region. Leaders' connections to different fisheries are evaluated, and these actors are found to be significantly more diversified than other fishers in the area. Drawing on theory related to institutional entrepreneurship and a series of in-depth interviews with these actors, this paper puts forward several hypotheses to explain how diverse social-ecological connections facilitate leadership...
May 17, 2017: Journal of Environmental Management
https://www.readbyqxmd.com/read/28526704/elder-women-s-perceptions-around-optimal-perinatal-health-a-constructivist-grounded-theory-study-with-an-indigenous-community-in-southern-ontario
#12
Sujane Kandasamy, Meredith Vanstone, Mark Oremus, Trista Hill, Gita Wahi, Julie Wilson, A Darlene Davis, Ruby Jacobs, Rebecca Anglin, Sonia Savitri Anand
BACKGROUND: Women play important roles in translating health knowledge, particularly around pregnancy and birth, in Indigenous societies. We investigated elder Indigenous women's perceptions around optimal perinatal health. METHODS: Using a methodological framework that integrated a constructivist grounded-theory approach with an Indigenous epistemology, we conducted and analyzed in-depth interviews and focus groups with women from the Six Nations community in southern Ontario who self-identified as grandmothers...
May 18, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28525780/age-of-despair-or-age-of-hope-palestinian-women-s-perspectives-on-midlife-health
#13
Doaa Hammoudeh, Ernestina Coast, David Lewis, Yoke van der Meulen, Tiziana Leone, Rita Giacaman
There is limited evidence about women's experiences of the midlife, beyond a narrow - frequently biomedical - focus on the menopause. The broader (physical, social, cultural, political) dimensions of women's midlife health are poorly understood, particularly in low and middle-income countries. Our study seeks to understand how women in the West Bank (occupied Palestinian territories) conceptualise, experience and manage their health in the midlife. We generated qualitative evidence using in-depth life history interviews in 2015 with women (n = 35) living in the West Bank, analysed thematically...
May 11, 2017: Social Science & Medicine
https://www.readbyqxmd.com/read/28522743/forward-to-the-past-the-case-for-quantitative-pet-imaging
#14
Adriaan A Lammertsma
Positron emission tomography (PET) was developed in the 1970's as an in vivo method to measure regional pathophysiological processes. In the 1990's the focus moved to the detection of local increases in uptake, first in the brain (activation studies) and later in oncology (finding metastases), where (18)F-FDG emerged as a highly sensitive staging technique. This focus on sensitivity has overshadowed the other main characteristic of PET, its quantitative nature. In recent years there has been a new shift. PET is now seen as a promising tool for drug development and precision medicine, i...
May 18, 2017: Journal of Nuclear Medicine: Official Publication, Society of Nuclear Medicine
https://www.readbyqxmd.com/read/28522208/wasted-food-wasted-nutrients-nutrient-loss-from-wasted-food-in-the-united-states-and-comparison-to-gaps-in-dietary-intake
#15
Marie L Spiker, Hazel A B Hiza, Sameer M Siddiqi, Roni A Neff
BACKGROUND: Previous research has estimated that wasted food in the United States contains between 1,249 and 1,400 kcal per capita per day, but little is known about amounts of other nutrients embedded in the 31% to 40% of food that is wasted. OBJECTIVE: This research aimed to calculate the nutritional value of food wasted at the retail and consumer levels in the US food supply, and contextualize the amount of nutrient loss in terms of gaps between current and recommended intakes and estimated food recovery potential...
May 11, 2017: Journal of the Academy of Nutrition and Dietetics
https://www.readbyqxmd.com/read/28521755/high-dietary-quality-of-non-toxic-cyanobacteria-for-a-benthic-grazer-and-its-implications-for-the-control-of-cyanobacterial-biofilms
#16
Sophie Groendahl, Patrick Fink
BACKGROUND: Mass occurrences of cyanobacteria frequently cause detrimental effects to the functioning of aquatic ecosystems. Consequently, attempts haven been made to control cyanobacterial blooms through naturally co-occurring herbivores. Control of cyanobacteria through herbivores often appears to be constrained by their low dietary quality, rather than by the possession of toxins, as also non-toxic cyanobacteria are hardly consumed by many herbivores. It was thus hypothesized that the consumption of non-toxic cyanobacteria may be improved when complemented with other high quality prey...
May 18, 2017: BMC Ecology
https://www.readbyqxmd.com/read/28521690/engineered-bone-tissue-with-naturally-derived-small-molecules
#17
Guleid Awale, Edgar Wong, Komal Rajpura, Kevin W-H Lo
Natural products remain the best resources of drugs and drug leads. Recently, there is growing recognition that identifying new small molecules to promote bone regeneration is a laudable translational goal. In fact, new approaches for bone repair and regeneration that involve inexpensive naturally-derived compounds would have an important impact on the treatment of bone disorders and injuries. Over the past several decades, a number of naturally-derived small molecules with the potential of regenerating bone tissue (i...
May 16, 2017: Current Pharmaceutical Design
https://www.readbyqxmd.com/read/28521385/-ziziphus-oxyphylla-ethnobotanical-ethnopharmacological-and-phytochemical-review
#18
REVIEW
Rizwan Ahmad, Niyaz Ahmad, Atta Abbas Naqvi
ETHNOPHARMACOLOGICAL RELEVANCE: Ziziphus oxyphylla (ZO) is distributed mainly in tropic and warm temperate regions in the world. Pakistan owns six (06) indigenous species of genus Ziziphus out of which ZO is widely used for traditional treatment of different ailments such as diabetes, jaundice and liver diseases. AIM OF THE STUDY: The present review aims to provide in-depth and comprehensive literature overview, regarding botanical, chemical and biological characteristics of the plant alongwith phytochemical isolation and mechanistic studies to support its folklore and traditional uses...
May 14, 2017: Biomedicine & Pharmacotherapy, Biomédecine & Pharmacothérapie
https://www.readbyqxmd.com/read/28521336/chemical-ecology-of-antibiotic-production-by-actinomycetes
#19
Anne van der Meij, Sarah F Worsley, Matthew I Hutchings, Gilles P van Wezel
Actinomycetes are a diverse family of filamentous bacteria that produce a plethora of natural products relevant for agriculture, biotechnology and medicine, including the majority of the antibiotics we use in the clinic. Rather than as free-living bacteria, many actinomycetes have evolved to live in symbiosis with among others plants, fungi, insects and sponges. As a common theme, these organisms profit from the natural products and enzymes produced by the actinomycetes, for example, for protection against pathogenic microbes, for growth promotion or for the degradation of complex natural polymers such as lignocellulose...
May 1, 2017: FEMS Microbiology Reviews
https://www.readbyqxmd.com/read/28517038/do-trainees-feel-that-they-belong-to-a-team
#20
Sophie Price, Rosie Lusznat
BACKGROUND: Postgraduate medical education has undergone significant reorganisation in recent years, with changes to the traditional apprenticeship model and an increasing reliance on shift working. The importance of teamwork in clinical care is well established; however, there is little literature on the extent to which trainees actually feel part of a team in the context of current working patterns. METHOD: This is a qualitative study using semi-structured interviews of medical and surgical trainees...
May 18, 2017: Clinical Teacher
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