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Postoperative adhesions

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https://www.readbyqxmd.com/read/28729217/preventing-postoperative-tissue-adhesion-using-injectable-carboxymethyl-cellulose-pullulan-hydrogels
#1
Sumi Bang, Young-Gwang Ko, Won Il Kim, Donghwan Cho, Won Ho Park, Oh Hyeong Kwon
An injectable adhesive hydrogel composed of carboxymethyl cellulose (CMC) and pullulan is developed and evaluated as a postoperative anti-adhesion barrier. CMC was modified with tyramine to introduce crosslinking via an EDC-NHS reaction. The in situ hydrogel was developed by an enzyme-mediated reaction of tyramine-immobilized CMC with horseradish peroxidase (HRP) and hydrogen peroxide (H2O2). Pullulan was added to the hydrogel solution to improve adhesiveness to the wound area and accelerate biodegradation...
July 17, 2017: International Journal of Biological Macromolecules
https://www.readbyqxmd.com/read/28721040/effect-of-ultraviolet-treatment-on-bacterial-attachment-and-osteogenic-activity-to-alkali-treated-titanium-with-nanonetwork-structures
#2
Honghao Zhang, Satoshi Komasa, Chiho Mashimo, Tohru Sekino, Joji Okazaki
PURPOSE: Alkali-treated titanium with nanonetwork structures (TNS) possesses good osteogenic activity; however, the resistance of this material to bacterial contamination remains inadequate. As such, TNS implants are prone to postoperative infection. In this work, we attempted to alter the biological properties of TNS by treatment with short-duration high-intensity ultraviolet (UV) irradiation. METHODS: TNS discs were treated with UV light (wavelength =254 nm, strength =100 mW/cm(2)) for 15 minutes using a UV-irradiation machine...
2017: International Journal of Nanomedicine
https://www.readbyqxmd.com/read/28717272/have-we-overcome-the-complications-of-laparoscopic-nephrectomy-a-prospective-cohort-study-using-the-modified-clavien-dindo-scale
#3
Tapan Agrawal, Rajeev Kumar, Prabhjot Singh, Ashish Saini, Amlesh Seth, Premnath Dogra
INTRODUCTION: Apart from the complexity of procedure and surgeon's experience, surgical complication rates depend on case definition and method of recording data. We prospectively evaluated the complications of laparoscopic nephrectomy (LN) in a current cohort of patients, graded on the modified Clavien-Dindo (CD) scale and compared them with historical cohorts. METHODS: In the Institutional Review Board approved protocol, all patients undergoing LN over a 30-month were enrolled in the study...
July 2017: Indian Journal of Urology: IJU: Journal of the Urological Society of India
https://www.readbyqxmd.com/read/28707149/long-term-quality-of-life-and-outcomes-following-robotic-assisted-tapp-inguinal-hernia-repair
#4
Andrew Iraniha, Joshua Peloquin
Laparoscopic TAPP inguinal hernia repair is an established alternative to open hernia repair, which offers equivalent outcomes with less postoperative pain and faster recovery. Unfortunately, it remains technically challenging, requiring advanced laparoscopic skills which have limited its popularity among surgeons. The robotic platform has the potential to overcome these challenges. The objective of this study was to examine the long-term quality of life and outcomes following robotic assisted TAPP inguinal hernia repair, since these data have not been reported up to now...
July 13, 2017: Journal of Robotic Surgery
https://www.readbyqxmd.com/read/28706891/evaluation-of-botulinum-toxin-type-a-effectiveness-in-preventing-postoperative-intraperitoneal-adhesions
#5
Mehmet Dokur, Erdal Uysal
PURPOSE: Postoperative intraperitoneal adhesions (PIAs) are one of the most important problems surgeons have to face after laparotomies. In this study, we aimed to evaluate the effectiveness of local application of botulinum toxin type A (BoNT-A) in various dosages on the prevention of intra-abdominal adhesions in rats with experimental intra-abdominal adhesions. METHODS: Forty Wistar Albino female rats were randomly separated into 4 groups. The 4 groups were determined as follows: Control (group 1, n = 10); Sham (group 2, n = 10); 10-µg/kg low-dose BoNT-A (group 3, n = 10) and 30-µg/kg high-dose BoNT-A (group 4, n = 10)...
July 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28703800/killing-two-birds-with-one-stone-dual-blockade-of-integrin-and-fgf-signaling-through-targeting-syndecan-4-in-postoperative-capsular-opacification
#6
Yingyan Qin, Yi Zhu, Furong Luo, Chuan Chen, Xiaoyun Chen, Mingxing Wu
The most common complication after cataract surgery is postoperative capsular opacification, which includes anterior capsular opacification (ACO) and posterior capsular opacification (PCO). Increased adhesion of lens epithelial cells (LECs) to the intraocular lens material surface promotes ACO formation, whereas proliferation and migration of LECs to the posterior capsule lead to the development of PCO. Cell adhesion is mainly mediated by the binding of integrin to extracellular matrix proteins, while cell proliferation and migration are regulated by fibroblast growth factor (FGF)...
July 13, 2017: Cell Death & Disease
https://www.readbyqxmd.com/read/28690123/pedicled-omental-flaps-in-the-treatment-of-complex-spinal-wounds-after-en-bloc-resection-of-spine-tumors
#7
Andrea Sambri, Alessandro Gasbarrini, Sergio Cialdella, Pierandrea De Iaco, Stefano Boriani
STUDY DESIGN: The present paper presents a retrospective study of 5 patients who underwent pedicled omental flap procedure following spine tumor removal. SUMMARY OF BACKGROUND DATA: Postoperative wound dehiscence represents a major complication in spinal surgery, particularly after en bloc tumor resection, because of the extended sacrifice of soft tissues and adjuvant radiation therapy and chemotherapy. METHODS: Five patients, with a mean age of 52 years (range, 24-71 years), who underwent omental flaps for the treatment of postoperative complication in spine tumor resections were retrospectively evaluated...
June 16, 2017: Journal of Plastic, Reconstructive & Aesthetic Surgery: JPRAS
https://www.readbyqxmd.com/read/28689686/clinical-evaluations-of-complete-autologous-fibrin-glue-produced-by-the-cryoseal-%C3%A2-fs-system-and-polyglycolic-acid-sheets-as-wound-coverings-after-oral-surgery
#8
Atsumu Kouketsu, Shinnosuke Nogami, Minami Yamada-Fujiwara, Hirokazu Nagai, Kensuke Yamauchi, Shiro Mori, Hitoshi Miyashita, Tadashi Kawai, Aritsune Matsui, Yoshihiro Kataoka, Norihisa Satomi, Yushi Ezoe, Satoko Abe, Yuri Takeda, Takeshi Tone, Bunnichi Hirayama, Tsuyoshi Kurobane, Kazuki Tashiro, Yuta Yanagisawa, Tetsu Takahashi
The CryoSeal(®) FS System has been recently introduced as an automated device for the production of complete fibrin glue from autologous plasma, rather than from pool allogenic or cattle blood, to prevent viral infection and allergic reaction. We evaluated the effectiveness of complete autologous fibrin glue and polyglycolic acid (PGA) sheet wound coverings in mucosa defect oral surgery. Postoperative pain, scar contracture, ingestion, tongue dyskinesia, and postoperative bleeding were evaluated in 12 patients who underwent oral (including the tongue) mucosa excision, and received a PGA sheet and an autologous fibrin glue covering...
June 10, 2017: Journal of Cranio-maxillo-facial Surgery
https://www.readbyqxmd.com/read/28685665/effect-of-sodium-hyaluronate-carboxymethyl-cellulose-guardix-sol-on-retear-rate-and-postoperative-stiffness-in-arthroscopic-rotator-cuff-repair-patients-a-prospective-cohort-study
#9
Jeung Yeol Jeong, Pill Ku Chung, Jae Chul Yoo
PURPOSE: Hyaluronate-based anti-adhesive agents are expected to enhance rotator cuff healing; however, their effect on the incidence and extent of postoperative complications such as stiffness and retears has not been investigated. METHODS: From July 2012 to February 2013, 80 patients undergoing arthroscopic rotator cuff repair surgery were prospectively enrolled. Forty patients were assigned to the control group, while the other 40 were assigned to the injection group and received a Guardix-sol injection immediately after surgery...
May 2017: Journal of Orthopaedic Surgery
https://www.readbyqxmd.com/read/28685387/postoperative-abdominal-adhesions-clinical-significance-and-advances-in-prevention-and-management
#10
Demetrios Moris, Jeffery Chakedis, Amir A Rahnemai-Azar, Ana Wilson, Mairead Marion Hennessy, Antonios Athanasiou, Eliza W Beal, Chrysoula Argyrou, Evangelos Felekouras, Timothy M Pawlik
Postoperative adhesions remain one of the more challenging issues in surgical practice. Although peritoneal adhesions occur after every abdominal operation, the density, time interval to develop symptoms, and clinical presentation are highly variable with no predictable patterns. Numerous studies have investigated the pathophysiology of postoperative adhesions both in vitro and in vivo. Factors such as type and location of adhesions, as well as timing and recurrence of adhesive obstruction remain unpredictable and poorly understood...
July 6, 2017: Journal of Gastrointestinal Surgery: Official Journal of the Society for Surgery of the Alimentary Tract
https://www.readbyqxmd.com/read/28679967/thoracoscopic-surgery-for-pneumothorax-following-outpatient-drainage-therapy
#11
Atsushi Sano, Takuma Yotsumoto
PURPOSE: We investigated the outcomes of surgery for pneumothorax following outpatient drainage therapy. METHODS: We reviewed the records of 34 patients who underwent operations following outpatient drainage therapy with the Thoracic Vent at our hospital between December 2012 and September 2016. Indications for outpatient drainage therapy were pneumothorax without circulatory or respiratory failure and pleural effusion. Indications for surgical treatment were persistent air leakage and patient preference for surgery to prevent or reduce the incidence of recurrent pneumothorax...
July 5, 2017: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/28673765/cyanoacrylate-adhesive-reduces-seroma-production-after-modified-radical-mastectomy-or%C3%A2-quadrantectomy-with-lymph-node-dissection-a-prospective-randomized-clinical%C3%A2-trial
#12
Kalliopi Vasileiadou, Christophoros Kosmidis, Georgios Anthimidis, Spiros Miliaras, Ioannis Kostopoulos, Epameinondas Fahantidis
INTRODUCTION: The accumulation of fluid, a seroma, is a frequent complication after modified radical mastectomy or quadrantectomy with lymph node dissection. The aim of the present study was to examine whether a new adhesive material made of cyanoacrylate can effectively provide a sealing coat to tissues and thus reduce the incidence of seroma significantly. PATIENTS AND METHODS: The present prospective, randomized case-control study included 128 women with a breast cancer diagnosis and scheduled for modified radical mastectomy or quadrantectomy with lymph node dissection in Thessaloniki, Greece...
April 13, 2017: Clinical Breast Cancer
https://www.readbyqxmd.com/read/28666687/autologous-peritoneal-grafts-permit-rapid-reperitonealization-and-prevent-postoperative-abdominal-adhesions-in-an-experimental-rat-study
#13
Lucie Bresson, Eric Leblanc, Anne Sophie Lemaire, Teru Okitsu, Feng Chai
BACKGROUND: Reperitonealization has attracted increasing attention for its potential to prevent postoperative abdominal adhesions and subsequent related complications. We studied the effect of an autologous peritoneal graft on reperitonealization and prevention of adhesions in a rat model. METHODS: A standardized peritoneal lesion was induced on the parietal peritoneum by electrocoagulation and sutures. Twenty adult rats sustaining these lesions were randomized to 1 of 4 groups: (1) autologuous peritoneal graft with the side of mesothelial cells exposed to the abdominal cavity; (2) autologuous peritoneal graft with the side of subserosa containing fibroblasts exposed to the abdominal cavity; (3) cell sheet consisting of autologuous mesothelial cells and fibroblasts; or (4) nontreated group (Control)...
June 27, 2017: Surgery
https://www.readbyqxmd.com/read/28665871/predictive-factors-of-visual-outcome-for-vitreomacular-traction-syndrome-after-vitrectomy
#14
Chang-Sue Yang, Ming-Hung Hsieh, Yu-Fan Chang, Chiao-Yu Wang, Shih-Jen Chen
PURPOSE: To assess the long-term functional and anatomical outcomes for vitreomacular traction syndrome (VMT) after vitrectomy and to analyze the predictive factors regarding visual outcome. METHODS: A retrospective, consecutive case series of 22 eyes in 22 patients with VMT who underwent vitrectomy to relieve macular edema were studied. Eyes were classified into two groups according to the diameter of vitreomacular adhesion based on spectral domain optical coherence tomography: Group 1 (14 eyes) focal attachment ≤1,500 μm; and Group 2 (eight eyes) broad attachment >1,500 μm...
June 29, 2017: Retina
https://www.readbyqxmd.com/read/28665387/-treatment-of-syringomyelia-associated-with-adhesive-arachnoiditis
#15
A A Zuev, V B Lebedev, N V Pedyash, D S Epifanov, R S Levin
The prevalence of syringomyelia (SM) caused by adhesive arachnoiditis (AA) is 2 to 4 cases per 100000 population. Surgical treatment of this pathology usually includes implantation of shunts into the cyst cavity or opening and drainage of the cavity. In this case, SM continues to progress in 72-100% of patients. Unsatisfactory outcomes of this surgical approach necessitate searching for other treatment options. PURPOSE: To define the optimal amount of surgery for SM associated with AA and the criteria for assessment of surgery outcomes...
2017: Zhurnal Voprosy Neĭrokhirurgii Imeni N. N. Burdenko
https://www.readbyqxmd.com/read/28662686/type-ii-peter-s-anomaly-with-histopathological-proof-a-case-report
#16
Rui-Qi Chang, Yu Du, Xiang-Jia Zhu, Yi Lu
BACKGROUND: Peter's anomaly is a rare congenital anterior segment dysgenesis with poor visual results. This case report describes a case of bilateral Type II Peter's anomaly with notable clinical and histopathological features. CASE PRESENTATION: A 7-year-old boy was admitted to our center with complaints of bilateral central opacification, photophobia and severe reduced vision since birth. He underwent phacoemulsification, intraocular lens (IOL) implantation and anterior vitrectomy on the right eye in another medical institution two years ago...
June 29, 2017: BMC Ophthalmology
https://www.readbyqxmd.com/read/28657827/comparison-of-transperitoneal-and-retroperitoneal-laparoscopic-nephrectomy-for-nonfunctional-tuberculous-kidneys-a-single-center-experience
#17
Yanxiong Chen, Haofeng Zheng, Guancan Liang, Dejuan Wang, Jianguang Qiu, Youqiang Fang
OBJECTIVES: To compare the effectiveness and safety between retroperitoneal laparoscopic nephrectomy (RLN) and transperitoneal laparoscopic nephrectomy (TLN) for nonfunctional tuberculous kidneys (NTK). METHODS: From March 2013 to February 2016, 24 patients with NTK underwent laparoscopic nephrectomy in our department. Eleven patients underwent RLN, and 13 underwent TLN. The demographics and perioperative outcomes were compared retrospectively. RESULTS: Characteristics, including gender, age, body mass index, and location, were similar in these two groups...
June 28, 2017: Journal of Laparoendoscopic & Advanced Surgical Techniques. Part A
https://www.readbyqxmd.com/read/28654851/a-colovesical-fistula-with-a-persistent-descending-mesocolon-due-to-partial-situs-inversus-a-case-report
#18
Tetsuya Mochizuki, Hirofumi Tazawa, Yuzo Hirata, Yoshio Kuga, Tomohiro Miwata, Sotaro Fukuhara, Kouki Imaoka, Seiji Fujisaki, Mamoru Takahashi, Saburo Fukuda, Toshihiro Nishida, Hideto Sakimoto
INTRODUCTION: Situs inversus viscerum, a congenital condition in which the visceral organs are a mirror image of their normal physiological positions, could be total or partial. Persistent descending mesocolon (PDM) is a congenital anomaly that is asymptomatic because of its short length. PDM causing intestinal obstruction is a known clinical complication. PRESENTATION OF CASE: A 74-year-old woman presented with pneumaturia and enteruria for two months, and recurrent cystitis for a month...
June 17, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28654705/effective-new-membrane-for-preventing-postthoracotomy-pleural-adhesion-by-surface-water-induction-technology
#19
Akiko Uemura, Mary Nakata, Seijirow Goya, Toshiharu Fukayama, Ryou Tanaka
BACKGROUND: After thoracic surgery, adhesions between the pleura can cause substantial complications. This study investigated the effectiveness of a novel membrane utilizing surface water induction technology to prevent adhesions. METHODS: Eight beagles were divided into an experimental group (five males) and a control group (three females). The experimental group underwent thoracotomy on both the left and right sides of the chest. Both sides received the membrane, and the membrane on one side was glued to the pleura using tissue adhesive...
2017: PloS One
https://www.readbyqxmd.com/read/28651806/von-willebrand-factor-deposition-and-adamts-13-consumption-in-allograft-tissue-of-thrombotic-microangiopathy-like-disorder-after-living-donor-liver-transplantation-a-case-report
#20
S Nakanuma, T Miyashita, H Hayashi, Y Ohbatake, H Takamura, M Okazaki, T Yamaguchi, S Sakai, I Makino, K Oyama, H Tajima, I Ninomiya, S Fushida, T Ohta
BACKGROUND: Thrombotic microangiopathy (TMA) pathogenesis after living donor liver transplantation (LDLT) is thought to be caused by release of unusually large von Willebrand factor multimers (UL-vWFMs) resulting from sinusoidal endothelial cell damage and induction of platelet adhesion and aggregation. A decrease in a disintegrin-like and metalloproteinase with thrombospondin type 1 motifs-13 (ADAMTS-13) that cleave UL-vWFMs might cause excessive UL-vWFMs activity and result in platelet thrombus formation...
June 23, 2017: Transplantation Proceedings
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