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Postoperative adhesions

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https://www.readbyqxmd.com/read/29793074/cross-linked-electrospun-cartilage-acellular-matrix-poly-caprolactone-co-lactide-co-glycolide-nanofiber-as-an-antiadhesive-barrier
#1
Jin Woo Lee, Joon Yeong Park, Seung Hun Park, Min Ju Kim, Bo Ram Song, Hee-Woong Yun, Tae Woong Kang, Hak Soo Choi, Young Jick Kim, Byoung Hyun Min, Moon Suk Kim
In this work, we chose cartilage acellular matrix (CAM) as a promising antiadhesive material because CAM effectively inhibits the formation of blood vessels, and we used electrospinning to prepare antiadhesive barriers. Additionally, we synthesized N-hydroxysuccinimide (NHS)-poly(caprolactone-co-lactide-co-glycolide)-NHS (MP) copolymers (to tune degradation) as a cross-linking agent for CAM. This is the first report on the development of electrospun cross-linked (Cx) CAM/MP (CA/P) nanofiber (NF) (Cx-CA/P-NF) with a tunable degradation period as an antiadhesive barrier...
May 21, 2018: Acta Biomaterialia
https://www.readbyqxmd.com/read/29789815/challenging-case-robot-assisted-laparoscopic-prostatectomy-after-prior-suprapubic-open-prostatectomy
#2
Shirin Razdan, Sanjay Razdan
Introduction: Given the ubiquity of robot-assisted laparoscopic prostatectomy (RALP) for treatment of localized prostate cancer, more surgeons are encountering challenging cases, either secondary to difficult anatomy, prior abdominal surgery, or prior radiation therapy. Our case is of RALP in a patient after prior suprapubic prostatectomy. Case Presentation: A 61-year-old otherwise healthy Hispanic gentleman presented for consultation after being found to have Gleason 4 + 4 = 8 prostate cancer on transrectal ultrasound-guided biopsy by an outside provider in July 2017...
2018: Journal of Endourology Case Reports
https://www.readbyqxmd.com/read/29784584/pelvic-adhesions-and-fertility-where-are-we-in-2018
#3
M Canis, R Botchorishvili, N Bourdel, A-S Gremeau, S Curinier, B Rabischong
Peritoneal adhesions remain a major public health problem despite the development of laparoscopy. The rules of microsurgery must be known and followed during any pelvic surgery, even in patients who no longer have a desire for pregnancy. Anti-adhesion products are numerous. All have interest, confirmed by anatomical studies showing a smaller extent or a lesser severity of adhesions associated with their use. No studies, however, show clinical benefit in terms of improved pain or postoperative fertility. Pneumoperitoneum parameters, humidification, and lower abdominal pressure should be optimized to limit peritoneal trauma...
May 18, 2018: Journal of Visceral Surgery
https://www.readbyqxmd.com/read/29783695/application-of-a-novel-anti-adhesive-membrane-e8002-in-a-rat-laminectomy-model
#4
Kiyoshi Kikuchi, Kentaro Setoyama, Takuto Terashi, Megumi Sumizono, Salunya Tancharoen, Shotaro Otsuka, Seiya Takada, Kazuki Nakanishi, Koki Ueda, Harutoshi Sakakima, Ko-Ichi Kawahara, Ikuro Maruyama, Gohsuke Hattori, Motohiro Morioka, Eiichiro Tanaka, Hisaaki Uchikado
Neuropathic pain after spinal surgery, so-called failed back surgery syndrome, is a frequently observed common complication. One cause of the pain is scar tissue formation, observed as post-surgical epidural adhesions. These adhesions may compress surrounding spinal nerves, resulting in pain, even after successful spinal surgery. E8002 is an anti-adhesive membrane. In Japan, a clinical trial of E8002 is currently ongoing in patients undergoing abdominal surgery. However, animal experiments have not been performed for E8002 in spinal surgery...
May 18, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29782336/a-review-of-small-incision-lenticule-extraction-complications
#5
Ronald R Krueger, Caio S Meister
PURPOSE OF REVIEW: As a flapless procedure, SMILE brings benefits to refractive surgery, such as lower corneal biomechanical impact, less dry eye risk and less stromal bed exposure. However, the longer learning curve can be a risk factor for complications. This article aims to discuss SMILE complications and proposes a categorized analysis of occurrences, dividing into two groups: intraoperative and postoperative complications. Among intraoperative, we also suggest a subdivision between those related to the laser (lenticule construction), tissue separation (lenticule dissection) and tissue removal (lenticule extraction)...
May 17, 2018: Current Opinion in Ophthalmology
https://www.readbyqxmd.com/read/29782222/clinical-effectiveness-of-a-resin-modified-glass-ionomer-cement-and-a-mild-one-step-self-etch-adhesive-applied-actively-and-passively-in-noncarious-cervical-lesions-an-18-month-clinical-trial
#6
M Jassal, S Mittal, S Tewari
OBJECTIVES: To evaluate the clinical effectiveness of two methods of application of a mild one-step self-etch adhesive and composite resin as compared with a resin-modified glass ionomer cement (RMGIC) control restoration in noncarious cervical lesions (NCCLs). METHODS: A total of 294 restorations were placed in 56 patients, 98 in each one of the following groups: 1) G-Bond active application combined with Solare-X composite resin (A-1SEA), 2) G-Bond passive application combined with Solare-X composite resin (P-1SEA), and 3) GC II LC RMGIC...
May 21, 2018: Operative Dentistry
https://www.readbyqxmd.com/read/29780074/communication-site-ligation-and-polyglycolic-acid-sheet-use-for-the-treatment-of-hydrothorax-in-patients-undergoing-continuous-ambulatory-peritoneal-dialysis
#7
Hirotoshi Kubokura, Junichi Okamoto, Jitsuo Usuda
INTRODUCTION: Hydrothorax due to pleuroperitoneal communication (PPC) can occur in patients undergoing continuous ambulatory peritoneal dialysis (CAPD). We report our experiences of the safety and efficacy of the treatment of four patients with a novel video-assisted thoracoscopy method. METHODS: Single-port video-assisted thoracoscopic surgery (VATS) was performed with a mini-thoracotomy of 5 cm in length. The PPC site was identified on the diaphragm and ligated using an endoscopic loop...
May 21, 2018: Annals of Thoracic and Cardiovascular Surgery
https://www.readbyqxmd.com/read/29778616/routine-portal-vein-resection-for-pancreatic-adenocarcinoma-shows-no-benefit-in-overall-survival
#8
Fritz Klein, Finja Berresheim, Matthäus Felsenstein, Thomas Malinka, Uwe Pelzer, Timm Denecke, Johann Pratschke, Marcus Bahra
BACKGROUND: Extended pancreatic resections including resections of the portal (PV) may nowadays be performed safely. Limitations in distinguishing tumor involvement from inflammatory adhesions however lead to portal vein resections (PVR) without evidence of tumor infiltration in the final histopathological examination. The aim of this study was to analyze the impact of these "false negative" resections on operative outcome and long-term survival. METHODS: 40 patients who underwent pancreatic resection with PVR for pancreatic adenocarcinoma (PA) without tumor infiltration of the PV (PVR-group) were identified...
May 9, 2018: European Journal of Surgical Oncology
https://www.readbyqxmd.com/read/29774937/-application-of-robotic-surgery-to-treat-carcinoma-in-the-remnant-stomach
#9
Feng Qian, Jiajia Liu, Junyan Liu, Junyan Fan, Yongliang Zhao, Yan Shi, Yingxue Hao, Peiwu Yu
OBJECTIVE: To explore the surgical techniques and feasibility of robotic surgery for carcinoma in the remnant stomach(CRS). METHODS: Clinicopathological data of 20 CRS patients undergoing robotic surgery at the Minimally Invasive Center for Gastrointestinal Surgery, Army Medical University Southwest Hospital from November 2012 to October 2017 were retrospectively collected. The surgical methods, procedures, main difficulties, and key techniques were analyzed, and the clinical efficacy was evaluated...
May 25, 2018: Zhonghua Wei Chang Wai Ke za Zhi, Chinese Journal of Gastrointestinal Surgery
https://www.readbyqxmd.com/read/29774817/bladder-reconstruction-with-bowel-robot-assisted-laparoscopic-ileocystoplasty-with-mitrofanoff-appendicovesicostomy-in-pediatric-patients
#10
Nimrod S Barashi, Maria Veronica Rodriguez, Vignesh T Packiam, Mohan S Gundeti
Neurogenic bladder occur as a consequence of several conditions, most commonly posterior urethral valves syndrome, spina bifida, tethered cord, sacral agenesis, and Arnold-Chiari malformation. It is characterized by diminished bladder capacity and/or reduced compliance, associated with high-pressure voiding that can lead to deterioration of renal function if left untreated. When medical management fails, bladder reconstruction with bowel (aumentation ileocystoplasty) becomes the treatment of choice for these patients...
May 2018: Journal of Endourology
https://www.readbyqxmd.com/read/29762437/primary-premaxillary-ostectomy-and-setback-dealing-with-the-fly-away-premaxilla
#11
Rana Farhadi, Robert D Wallace
OBJECTIVE: This study aimed to analyze our outcomes of primary premaxillary ostectomy and setback combined with lip adhesion as the first stage in repair of the bilateral cleft lip with fly-away premaxilla. METHODS: This retrospective study included all patients who required primary premaxillary setback by a single surgeon to achieve successful lip repair between 2011 and 2017 at a tertiary children's hospital. All patients had bilateral cleft lip and complete cleft palate with significant premaxillary protrusion...
May 14, 2018: Annals of Plastic Surgery
https://www.readbyqxmd.com/read/29759510/predicting-morbidity-after-robotic-partial-nephrectomy-the-effect-of-tumor-environment-and-patient-related-factors
#12
Zine-Eddine Khene, Benoit Peyronnet, Neil J Kocher, Haley Robyak, Corentin Robert, Benjamin Pradere, Emmanuel Oger, Solène-Florence Kammerer-Jacquet, Grégory Verhoest, Nathalie Rioux-Leclercq, Romain Mathieu, Jay D Raman, Karim Bensalah
PURPOSE: To investigate the effect of tumor and nontumor related parameters on perioperative outcomes of robotic partial nephrectomy (RPN). PATIENTS AND METHODS: Patients who underwent RPN for a localized renal tumor at 2 institutions between June 2010 and November 2016 were reviewed. RENAL and Mayo adhesive probability (MAP) scores were calculated and information on comorbid conditions including ASA score, performance status, Charlson's comorbidity index (CCI), and history of cardiovascular disease was collected...
May 11, 2018: Urologic Oncology
https://www.readbyqxmd.com/read/29747357/-research-on-the-effect-of-biological-glue-on-augmenting-the-viscosity-of-tissue-engineering-retinal-nerve-scaffolds
#13
K J Li, S J Yang, K Li, Y T Wei, J Zhuang, Y H Zhuo, J Ge
Objective: To evaluate the adhesion effect of tissue engineering retinal nerve scaffolds modified with biological glue. Methods: Experimental study. To fabricate a biological glue by blending laminin, collagen Ⅳ, entactin and HSPG(2) with phosphate-buffered saline (PBS) buffer solution, scaffolds were then modified with the biological glue of various concentration levels (10 μl/cm(2), 20 μl/cm(2), 30 μl/cm(2) and 40 μl/cm(2)). The effects of various concentration levels glue on inducing scaffold adhesion were analyzed after 24 h...
April 11, 2018: [Zhonghua Yan Ke za Zhi] Chinese Journal of Ophthalmology
https://www.readbyqxmd.com/read/29734717/thermosensitive-injectable-hydrogel-for-simultaneous-intraperitoneal-delivery-of-doxorubicin-and-prevention-of-peritoneal-adhesion
#14
Chih-Hao Chen, Chang-Yi Kuo, Shih-Hsien Chen, Shih-Hsuan Mao, Chih-Yen Chang, K T Shalumon, Jyh-Ping Chen
To improve intraperitoneal chemotherapy and to prevent postsurgical peritoneal adhesion, we aimed to develop a drug delivery strategy for controlled release of a chemotherapeutic drug from the intraperitoneally injected thermosensitive poly( N -isopropylacrylamide)-based hydrogel (HACPN), which is also endowed with peritoneal anti-adhesion properties. Anticancer drug doxorubicin (DOX) was loaded into the hydrogel (HACPN-DOX) to investigate the chemotherapeutic and adhesion barrier effects in vivo. A burst release followed by sustained release of DOX from HACPN-DOX was found due to gradual degradation of the hydrogel...
May 4, 2018: International Journal of Molecular Sciences
https://www.readbyqxmd.com/read/29730917/-laparoscopic-type-c1-hysterectomy-based-on-the-anatomic-landmark-of-the-uterus-deep-vein-and-its-branches-for-cervical-cancer
#15
M R Liang, D X Han, W Jiang, H Liu, L Li, M L Zhong, L Luo, S Y Zeng
Objective: To introduce the laparoscopic type C1 hysterectomy based on the anatomic landmark of the uterus deep vein and its branched and to evaluate its feasibility and safety for cervical cancer and its effect to bladder function and to provide some reference to simplify the surgical procedures of laparoscopic type C1 hysterectomy. Methods: The clinicopathologic data of the patients with stage ⅠA2~ⅡB cervical cancer and who underwent the laparoscopic C1 hysterectomy based on anatomic landmark of the uterus deep vein and its branches between March 2010 and December 2015 was retrospectively analysed...
April 23, 2018: Zhonghua Zhong Liu za Zhi [Chinese Journal of Oncology]
https://www.readbyqxmd.com/read/29721359/acute-cauda-equina-syndrome-following-orthopedic-procedures-as-a-result-of-epidural-anesthesia
#16
Lisa B E Shields, Vasudeva G Iyer, Yi Ping Zhang, Christopher B Shields
Background: Cauda equina syndrome (CES) is a rare complication of spinal or epidural anesthesia. It is attributed to direct mechanical injury to the spinal roots of the cauda equina that may result in saddle anesthesia and paraplegia with bowel and bladder dysfunction. Case Description: The first patient underwent a hip replacement and received 5 mL of 1% lidocaine epidural anesthesia. Postoperatively, when the patient developed an acute CES, the lumbar magnetic resonance imaging (MRI) scan demonstrated clumping/posterior displacement of nerve roots of the cauda equina consistent with adhesive arachnoiditis attributed to the patient's previous L4-L5 lumbar decompression/fusion...
2018: Surgical Neurology International
https://www.readbyqxmd.com/read/29718559/feasibility-of-early-discharge-following-vaginal-hysterectomy-with-a-bipolar-electrocoagulation-device
#17
Charlotte Cassis, Sambit Mukhopadhyay, Medha M Sule, Neeraja Kuruba
OBJECTIVE: To evaluate the safety and efficacy of vaginal hysterectomy for benign conditions (excluding prolapse) using the BiClamp (Erbe Elektromedizin, Tübingen, Germany) bipolar electrocoagulation system. METHODS: The present study was a prospective audit of a consecutive case series of patients who underwent vaginal hysterectomy for benign conditions, performed using the BiClamp between March 1, 2015, and June 30, 2016, at Norfolk and Norwich University Hospital, Norwich, UK...
May 2, 2018: International Journal of Gynaecology and Obstetrics
https://www.readbyqxmd.com/read/29716732/different-nuss-procedures-and-risk-management-for-pectus-excavatum-after-surgery-for-congenital-heart-disease
#18
Chenghao Chen, Xiaofeng Li, Na Zhang, Jie Yu, Dong Yan, Changqi Xu, Qi Zeng, Zhongzhi Li
PURPOSE: In Nuss procedure for pectus excavatum (PE) after surgery for congenital heart disease (CHD), retrosternal adhesion may increase the risk of cardiac injury. This study aimed to explore different Nuss procedures and their implications for reducing the incidence of serious complications and improving surgical safety. METHODS: We retrospectively reviewed 49 cases (29 male and 20 female) of Nuss procedures for PE after surgery for CHD that were performed between April 2003 and December 2016...
April 7, 2018: Journal of Pediatric Surgery
https://www.readbyqxmd.com/read/29715706/needlescopic-video-assisted-thoracic-bilateral-t4-sympathicotomy-for-the-treatment-of-primary-palmar-hyperhidrosis-an-analysis-of-200-cases
#19
Xing Feng, Xiaoling Xiong, Er Jin, Wen Meng
BACKGROUND:  Primary palmar hyperhidrosis (PPH) is featured by aberrantly perspiration of the hands, which may bring a lot of inconvenience to patient's daily life and work. The purpose of this study is to summarize the clinical effect of needlescopic video-assisted thoracic bilateral T4 sympathicotomy for the treatment of PPH. PATIENTS AND METHODS:  Between January 2009 and March 2014, 200 patients received needlescopic video-assisted thoracic bilateral T4 sympathicotomy...
May 1, 2018: Thoracic and Cardiovascular Surgeon
https://www.readbyqxmd.com/read/29715511/increased-neuroligin-2-levels-in-the-postsynaptic-membrane-in-spinal-dorsal-horn-may-contribute-to-postoperative-pain
#20
Ruijuan Guo, Huili Li, Xueyang Li, Yuqing Sun, Huihui Miao, Danxu Ma, Fangxiao Hong, Ye Zhang, Yun Guan, Junfa Li, Ming Tian, Yun Wang
Neuroligin 2 is a synaptic cell adhesion molecule that is mainly located in inhibitory synapses and is crucial in the regulation of synapse function through protein-protein interactions. However, researchers have not clearly determined whether neuroligin 2 is involved in the development of postoperative pain. In the current study, Western blot, immunofluorescence staining and co-immunoprecipitation were used to examine the critical role of neuroligin 2 in postoperative pain hypersensitivity. A small interfering ribonucleic acid (siRNA)-targeting neuroligin 2 was used to inhibit neuroligin 2 expression...
April 30, 2018: Neuroscience
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