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https://www.readbyqxmd.com/read/28917949/linear-association-between-number-of-modifiable-risk-factors-and-multiple-chronic-conditions-results-from-the-behavioral-risk-factor-surveillance-system
#1
Mary L Adams, Joseph Grandpre, David L Katz, Douglas Shenson
Multiple (≥2) chronic conditions (MCCs) are responsible for a large fraction of healthcare costs. Our aim was to examine possible associations between MCCs and composite measures of behavioral risk factors (RFs). Data were publicly available 2013 Behavioral Risk Factor Surveillance System and included 483,865 non-institutionalized US adults ages ≥18years. Chronic conditions included asthma, arthritis, chronic obstructive pulmonary disease, cognitive impairment, heart disease, stroke, cancer, and kidney disease...
September 13, 2017: Preventive Medicine
https://www.readbyqxmd.com/read/28911532/bioactive-phytochemicals-in-barley
#2
REVIEW
Emmanuel Idehen, Yao Tang, Shengmin Sang
Epidemiological studies have consistently shown that regular consumption of whole grain barley reduces the risk of developing chronic diseases. The presence of barley fiber, especially β-glucan in whole grain barley, has been largely credited for these health benefits. However, it is now widely believed that the actions of the fiber component alone do not explain the observed health benefits associated with the consumption of whole grain barley. Whole grain barley also contains phytochemicals including phenolic acids, flavonoids, lignans, tocols, phytosterols, and folate...
January 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28910310/gugulipid-causes-hypercholesterolemia-leading-to-endothelial-dysfunction-increased-atherosclerosis-and-premature-death-by-ischemic-heart-disease-in-male-mice
#3
Andrea Leiva, Susana Contreras-Duarte, Ludwig Amigo, Esteban Sepúlveda, Mauricio Boric, Verónica Quiñones, Dolores Busso, Attilio Rigotti
For proper cholesterol metabolism, normal expression and function of scavenger receptor class B type I (SR-BI), a high-density lipoprotein (HDL) receptor, is required. Among the factors that regulate overall cholesterol homeostasis and HDL metabolism, the nuclear farnesoid X receptor plays an important role. Guggulsterone, a bioactive compound present in the natural product gugulipid, is an antagonist of this receptor. This natural product is widely used globally as a natural lipid-lowering agent, although its anti-atherogenic cardiovascular benefit in animal models or humans is unknown...
2017: PloS One
https://www.readbyqxmd.com/read/28910267/surveillance-for-certain-health-behaviors-and-conditions-among-states-and-selected-local-areas-behavioral-risk-factor-surveillance-system-united-states-2013-and-2014
#4
Sonya Gamble, Tebitha Mawokomatanda, Fang Xu, Pranesh P Chowdhury, Carol Pierannunzi, David Flegel, William Garvin, Machell Town
PROBLEM: Chronic diseases and conditions (e.g., heart diseases, stroke, arthritis, and diabetes) are the leading causes of morbidity and mortality in the United States. These conditions are costly to the U.S. economy, yet they are often preventable or controllable. Behavioral risk factors (e.g., excessive alcohol consumption, tobacco use, poor diet, frequent mental distress, and insufficient sleep) are linked to the leading causes of morbidity and mortality. Adopting positive health behaviors (e...
September 15, 2017: MMWR. Surveillance Summaries: Morbidity and Mortality Weekly Report. Surveillance Summaries
https://www.readbyqxmd.com/read/28899889/neck-circumference-and-clustered-cardiovascular-risk-factors-in-children-and-adolescents-cross-sectional-study
#5
José Castro-Piñero, Alvaro Delgado-Alfonso, Luis Gracia-Marco, Sonia Gómez-Martínez, Irene Esteban-Cornejo, Oscar L Veiga, Ascensión Marcos, Víctor Segura-Jiménez
OBJECTIVE: Early detection of cardiovascular disease (CVD) risk factors, such as obesity, is crucial to prevent adverse long-term effects on individuals' health. Therefore, the aims were: (1) to explore the robustness of neck circumference (NC) as a predictor of CVD and examine its association with numerous anthropometric and body composition indices and (2) to release sex and age-specific NC cut-off values to classify youths as overweight/obese. DESIGN: Cross-sectional study...
September 11, 2017: BMJ Open
https://www.readbyqxmd.com/read/28893629/obesity-and-type-2-diabetes-not-a-diet-high-in-fat-sucrose-and-cholesterol-negatively-impacts-bone-outcomes-in-the-hyperphagic-otsuka-long-evans-tokushima-fatty-rat
#6
Laura C Ortinau, Melissa A Linden, Rebecca Dirkes, R Scott Rector, Pamela S Hinton
BACKGROUND: Obesity and type 2 diabetes (T2D) increase fracture risk; however, the association between obesity/T2D may be confounded by consumption of a diet high in fat, sucrose, and cholesterol (HFSC). OBJECTIVE: The study objective was to determine the main and interactive effects of obesity/T2D and a HFSC diet on bone outcomes using hyperphagic Otuska Long Evans Tokushima Fatty (OLETF) rats and normophagic Long Evans Tokushima Otsuka (LETO) controls. METHODS: At 8weeks of age, male OLETF and LETO rats were randomized to either a control (CON, 10 en% from fat as soybean oil) or HFSC (45 en% from fat as soybean oil/lard, 17 en% sucrose, and 1wt%) diet, resulting in four treatment groups...
September 9, 2017: Bone
https://www.readbyqxmd.com/read/28891316/associations-of-the-abca1-and-lpl-gene-polymorphisms-with-lipid-levels-in-a-hyperlipidemic-population
#7
Fang Tao, Justin Weinstock, Scott A Venners, Jun Cheng, Yi-Hsiang Hsu, Yanfeng Zou, Faming Pan, Shanqun Jiang, Xiangdong Zha, Xiping Xu
We conducted a cross-sectional study to investigate the effects of the adenosine triphosphate-binding cassette transporter 1 (ABCA1) I883M and lipoprotein lipase (LPL) HindIII polymorphisms on lipid levels in patients with hyperlipidemia. A total of 533 patients were enrolled. Serum lipid parameters were determined by an automatic biochemistry analyzer. Genotyping of the ABCA1 I883M and LPL HindIII was carried out using the polymerase chain reaction-restriction fragment length polymorphism technique. Multiple linear regression analysis was used to estimate the associations between serum lipid levels and the genetic polymorphisms...
January 1, 2017: Clinical and Applied Thrombosis/hemostasis
https://www.readbyqxmd.com/read/28888344/plasma-retinol-binding-protein-4-levels-and-the-risk-of-ischemic-stroke-among-women
#8
Pamela M Rist, Monik C Jiménez, Shelley S Tworoger, Frank B Hu, JoAnn E Manson, Qi Sun, Kathryn M Rexrode
BACKGROUND: Plasma retinol-binding protein 4 (RBP4) levels have been associated with cardiovascular risk factors and risk of coronary heart disease, but little is known about the association between RBP4 and the risk of ischemic stroke. We hypothesized that elevated RBP4 levels would be associated with an increased risk of ischemic stroke among women. METHODS: We performed a nested case-control study among women enrolled in the Nurses' Health Study who provided blood samples between 1989 and 1990 and were free of prior stroke and cancer...
September 6, 2017: Journal of Stroke and Cerebrovascular Diseases: the Official Journal of National Stroke Association
https://www.readbyqxmd.com/read/28882065/annals-express-serum-high-sensitive-c-reactive-protein-is-associated-with-dietary-intakes-in-diabetic-patients-with-and-without-hypertension-a-cross-sectional-study
#9
Mohammad Bagherniya, Sayyed Saeid Khayyatzadeh, Ali Reza Heidari-Bakavoli, Gordon Ferns, Mahmoud Ebrahimi, Mohammad Safarian, Mohsen Nematy, Majid Ghayour-Mobarhan
BACKGROUND: Serum high sensitive C-reactive protein (hs-CRP) concentrations independently predict the development of diabetes, metabolic syndrome and cardiovascular disease. However, the impact of dietary factors on serum hs-CRP concentrations in diabetic patients has received limited attention. We aimed to investigate the association between dietary factors and hs-CRP, among diabetic patients with and without hypertension and healthy subjects. METHODS: In this cross-sectional study, diabetics with (n=325) and without hypertension (n=599) and healthy individuals (n=1220) were recruited in Mashhad, Iran...
January 1, 2017: Annals of Clinical Biochemistry
https://www.readbyqxmd.com/read/28879825/changes-in-consumption-of-food-away-from-home-and-intakes-of-energy-and-other-nutrients-among-us-working-age-adults-2005-2014
#10
Jessica E Todd
OBJECTIVE: To document changes in consumption of food away from home (FAFH) and intakes of selected nutrients by working-age adults between 2005-06 and 2013-14, covering the most recent recessionary period and recovery. DESIGN: Means were compared across survey rounds relative to 2005-06. Multivariate regression was used to account for changes in demographic characteristics over time. SETTING: National Health and Nutrition Examination Survey (NHANES), 2005-2014...
September 7, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28869919/cardiometabolic-health-in-asians-with-diabetes-in-the-us
#11
Andy Menke, Sarah Casagrande, Catherine C Cowie
AIMS: Asians develop diabetes at lower levels of adiposity than people of other race/ethnicities. However, there is limited data investigating the health of US Asians with diabetes. We compared cardiovascular risk factors in US Asians to other race/ethnicities stratified by diabetes status. METHODS: Among 4645 adults in the 2011-2014 National Health and Nutrition Examination Survey (NHANES), a cross-sectional survey of the US population, odds ratios were calculated for obesity, hypertension, and elevated low-density lipoprotein (LDL) cholesterol associated with race/ethnicity after adjustment for age, sex, income, education, smoking, alcohol consumption, and health insurance...
August 12, 2017: Diabetes Research and Clinical Practice
https://www.readbyqxmd.com/read/28860221/large-scale-analysis-of-determinants-stability-and-heritability-of-high-density-lipoprotein-cholesterol-efflux-capacity
#12
Andrea L Koekemoer, Veryan Codd, Nicholas G D Masca, Christopher P Nelson, Muntaser D Musameh, Bernhard M Kaess, Christian Hengstenberg, Daniel J Rader, Nilesh J Samani
OBJECTIVE: Cholesterol efflux capacity (CEC) has emerged as a biomarker of coronary artery disease risk beyond plasma high-density lipoprotein (HDL) cholesterol (HDL-C) level. However, the determinants of CEC are incompletely characterized. We undertook a large-scale family-based population study to identify clinical, biochemical, and HDL particle parameter determinants of CEC, characterize reasons for the discordancy with HDL-C, quantify its heritability, and assess its stability over 10 to 12 years...
August 31, 2017: Arteriosclerosis, Thrombosis, and Vascular Biology
https://www.readbyqxmd.com/read/28859472/fish-consumption-mercury-exposure-and-the-risk-of-cholesterol-profiles-findings-from-the-korea-national-health-and-nutrition-examination-survey-2010-2011
#13
Yong Min Cho
Objectives: In this study, the associations between mercury exposure and cholesterol profiles were analyzed, and increased mercury levels and cholesterol profiles according to the amount of fish consumption were evaluated. Methods: Data on levels of blood mercury, the frequency of fish consumption, total blood cholesterol (TC), high-density lipoprotein cholesterol (HDL-C), low-density lipoprotein cholesterol (LDL-C), and triglyceride (TG) in 3,951 adults were obtained from the Korea National Health and Nutrition Examination Survey (KNHANES) 2010-2011 database...
August 31, 2017: Environmental Health and Toxicology
https://www.readbyqxmd.com/read/28856433/effects-of-orthodox-religious-fasting-on-human-health-a-systematic-review
#14
REVIEW
Theocharis Koufakis, Spyridon Ν Karras, Vasiliki Antonopoulou, Eleni Angeloudi, Pantelis Zebekakis, Kalliopi Kotsa
PURPOSE: Different studies have pointed towards a positive effect of religious fasting on human health. Orthodox fasting (OF) regime could be characterized as a periodical vegetarian diet, demonstrating several common characteristics with the typical Mediterranean diet. The present systematic review aimed to synthesize available results regarding the potential impact of OF on human health. METHODS: Key biomedical databases were searched to identify studies examining the effects of OF on humans...
August 30, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28854720/combined-androgen-excess-and-western-style-diet-accelerates-adipose-tissue-dysfunction-in-young-adult-female-nonhuman-primates
#15
Oleg Varlamov, Cecily V Bishop, Mithila Handu, Diana Takahashi, Sathya Srinivasan, Ashley White, Charles T Roberts
STUDY QUESTION: What are the separate and combined effects of mild hyperandrogenemia and consumption of a high-fat Western-style diet (WSD) on white adipose tissue (WAT) morphology and function in young adult female nonhuman primates? SUMMARY ANSWER: Combined exposure to mild hyperandrogenemia and WSD induces visceral omental (OM-WAT) but not subcutaneous (SC-WAT) adipocyte hypertrophy that is associated with increased uptake and reduced mobilization of free fatty acids...
September 1, 2017: Human Reproduction
https://www.readbyqxmd.com/read/28853910/coffee-consumption-and-disease-correlations
#16
Buşra Basar Gokcen, Nevin Sanlİer
Coffee is one of the most widely consumed beverages in the world. It has primarily consumed due to its stimulant effect and unique taste since the ancient times. Afterwards, its consumption has been historically associated with a lower risk of some diseases such as type 2 diabetes mellitus, obesity, cardiovascular disease and some type of cancer and thus it has also consumed due to health benefits. It contains many bioactive compounds such as caffeine, chlorogenic acids and diterpenoid alcohols which have so far been associated with many potential health benefits...
August 30, 2017: Critical Reviews in Food Science and Nutrition
https://www.readbyqxmd.com/read/28846611/high-intensity-exercise-can-it-protect-you-from-a-fast-food-diet
#17
Christian Duval, Marc-Antoine Rouillier, Rémi Rabasa-Lhoret, Antony D Karelis
The purpose of this study was to assess the ability of high intensity exercise to counteract the deleterious effects of a fast food diet on the cardiometabolic profile of young healthy men. Fifteen men were subjected to an exclusive fast food diet from a popular fast food restaurant chain (three extra value meals/day + optional snack) for 14 consecutive days. Simultaneously, participants were asked to perform each day high intensity interval training (HIIT) (15 × 60 sec sprint intervals (~90% of maximal heart rate)) on a treadmill...
August 26, 2017: Nutrients
https://www.readbyqxmd.com/read/28839130/work-stress-anthropometry-lung-function-blood-pressure-and-blood-based-biomarkers-a-cross-sectional-study-of-43-593-french-men-and-women
#18
Linda L Magnusson Hanson, Hugo Westerlund, Marcel Goldberg, Marie Zins, Jussi Vahtera, Naja Hulvej Rod, Sari Stenholm, Andrew Steptoe, Mika Kivimäki
Work stress is a risk factor for cardio-metabolic diseases, but few large-scale studies have examined the clinical profile of individuals with work stress. To address this limitation, we conducted a cross-sectional study including 43,593 working adults from a French population-based sample aged 18-72 years (the CONSTANCES cohort). According to the Effort-Reward Imbalance model, work stress was defined as an imbalance between perceived high efforts and low rewards at work. A standardized health examination included measures of anthropometry, lung function, blood pressure and standard blood-based biomarkers...
August 24, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28835245/prevalence-of-dyslipidaemia-and-risk-factors-in-chinese-coal-miners-a-cross-sectional-survey-study
#19
Ye Fan, Jian-Jun Huang, Chen-Ming Sun, Nan Qiao, Hai-Xia Zhang, Hui Wang, Ran Tao, Ya-Nan Shen, Tong Wang
BACKGROUND: Although coal miners are susceptible to dyslipidaemia owing to their highly risky and stressful working environment as well as unhealthy lifestyle, very few studies have focused on this issue thus far. Therefore, this study investigated the current epidemiological characteristics of dyslipidaemia among Chinese coal miners. METHODS: Demographic, anthropometric, and biochemical data were gathered from 4341 coal miners in China. Dyslipidaemia was diagnosed based on the serum lipid levels...
August 23, 2017: Lipids in Health and Disease
https://www.readbyqxmd.com/read/28834784/determination-of-fat-content-in-chicken-hamburgers-using-nir-spectroscopy-and-the-successive-projections-algorithm-for-interval-selection-in-pls-regression-ispa-pls
#20
Gabriela Krepper, Florencia Romeo, David Douglas de Sousa Fernandes, Paulo Henrique Gonçalves Dias Diniz, Mário César Ugulino de Araújo, María Susana Di Nezio, Marcelo Fabián Pistonesi, María Eugenia Centurión
Determining fat content in hamburgers is very important to minimize or control the negative effects of fat on human health, effects such as cardiovascular diseases and obesity, which are caused by the high consumption of saturated fatty acids and cholesterol. This study proposed an alternative analytical method based on Near Infrared Spectroscopy (NIR) and Successive Projections Algorithm for interval selection in Partial Least Squares regression (iSPA-PLS) for fat content determination in commercial chicken hamburgers...
August 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
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