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https://www.readbyqxmd.com/read/28527105/association-between-lumbar-bone-mineral-density-and-serum-uric-acid-in-postmenopausal-women-a-cross-sectional-study-of-healthy-chinese-population
#1
Wen Han, Xiaojuan Bai, Nan Wang, Lulu Han, Xuefeng Sun, Xiangmei Chen
Partial correlation and regression analyses were used in this study. We showed that there is a linear relationship between bone mineral density and serum uric acid within the normal physiologic range, and higher serum uric acid levels had a protective effect on bone loss in postmenopausal osteoporosis. PURPOSE: The significance of the relationship between lumbar bone mineral density (()BMD) and serum uric acid (SUA) levels is unclear. The aims of this study were to investigate on a population-level the association between lumbar BMD and SUA within the normal physiologic range and to determine whether SUA plays a protective role in bone loss in healthy postmenopausal Chinese women...
December 2017: Archives of Osteoporosis
https://www.readbyqxmd.com/read/28526391/withdrawal-from-high-carbohydrate-high-saturated-fat-diet-changes-saturated-fat-distribution-and-improves-hepatic-low-density-lipoprotein-receptor-expression-to-ameliorate-metabolic-syndrome-in-rats
#2
Ankita Hazarika, Himadri Kalita, Mohan Chandra Kalita, Rajlakshmi Devi
OBJECTIVE: The "lipid hypothesis" determined that saturated fatty acid (SFA) raises low-density lipoprotein cholesterol, thereby increasing the risk for metabolic syndrome (MetS). The aim of this study was to investigate the effect of subchronic withdrawal from a high-carbohydrate, high-saturated fat (HCHF) diet during MetS with reference to changes in deleterious SFA (C12:0, lauric acid; C14:0, myristic acid; C16:0, palmitic acid; C18:0, stearic acid) distribution in liver, white adipose tissue (WAT), and feces...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28526377/orange-juice-allied-to-a-reduced-calorie-diet-results-in-weight-loss-and-ameliorates-obesity-related-biomarkers-a-randomized-controlled-trial
#3
Carolina Ribeiro, Grace Dourado, Thais Cesar
OBJECTIVE: Assumptions have linked orange juice (OJ) consumption with weight gain and adverse effects on health due to its sugar content; however, epidemiologic studies have not shown increased risk for overweight or obesity with the consumption of 100% OJ. The aim of this study was to verify whether the combination of a reduced-calorie diet (RCD) and 100% OJ contribute to weight loss, promote changes in glucose and lipid metabolism, and improve diet quality in obese individuals. METHODS: A randomized controlled trial with 78 obese patients (age 36 ± 1 y, body mass index [BMI] 33 ± 3 kg/m(2)) were enrolled in two groups: Individuals in the OJ group submitted to an RCD that included OJ (500 mL/d), and individuals in the control group submitted to an RCD without OJ...
June 2017: Nutrition
https://www.readbyqxmd.com/read/28521683/impact-of-red-wine-consumption-on-cardiovascular-health
#4
Luca Liberale, Aldo Bonaventura, Fabrizio Montecucco, Franco Dallegri, Federico Carbone
The devastating effects of heavy alcohol drinking have been long time recognized. In the last decades, potential benefits of modest red wine drinking were suggested. In European countries in which red wide intake is not negligible (such as France), the association between cholesterol and cardiovascular (CV) risk was less evident, suggesting the action of some protective molecules in red wine or other foods and drinks. Epidemiological and mechanistic evidence of a J-shaped relationship between red wine intake and CV risk further supported the "French paradox"...
May 17, 2017: Current Medicinal Chemistry
https://www.readbyqxmd.com/read/28516793/red-or-white-wine-consumption-effect-on-atherosclerosis-in-healthy-individuals-in-vino-veritas-study
#5
M Taborsky, P Ostadal, T Adam, O Moravec, V Gloger, A Schee, T Skala
AIMS: Consumption of wine has a protective effect on cardiovascular diseases. Data from prospective, long-term, head-to-head comparisons of effects of different drinks on markers of atherosclerosis have been insufficient. METHODS AND RESULTS: In Vino Veritas (IVV) study is long-term, prospective, multi-centre, randomized trial comparing effects of red and white wine on atherosclerosis. 157 healthy subjects were randomized to white or red wine consumption for one year...
2017: Bratislavské Lekárske Listy
https://www.readbyqxmd.com/read/28515677/brain-control-of-plasma-cholesterol-involves-polysialic-acid-molecules-in-the-hypothalamus
#6
Xavier Brenachot, Thomas Gautier, Emmanuelle Nédélec, Valérie Deckert, Amélie Laderrière, Danaé Nuzzaci, Caroline Rigault, Aleth Lemoine, Luc Pénicaud, Laurent Lagrost, Alexandre Benani
The polysialic acid (PSA) is a large glycan that is added to cell-surface proteins during their post-translational maturation. In the brain, PSA modulates distances between cells and controls the plasticity of the nervous system. In the hypothalamus, PSA is involved in many aspects of energy balance including food intake, osmoregulation, circadian rhythm, and sleep. In this work, we investigated the role of hypothalamic PSA in the regulation of plasma cholesterol levels and distribution. We report that HFD consumption in mice rapidly increased plasma cholesterol, including VLDL, LDL, and HDL-cholesterol...
2017: Frontiers in Neuroscience
https://www.readbyqxmd.com/read/28507408/effect-of-dietary-supplementation-of-fermented-fish-silage-on-serum-biochemical-parameters-of-broiler-japanese-quails-coturnix-coturnix-japonica
#7
Sasmita Panda, Laxman Kumar Babu, Arun Kumar Panda, Tanuja S, Anurag Mohanty, Kuldeep Kumar Panigrahy, Pinaki Samal
AIM: The objective of this study was to evaluate the effect of feeding fermented fish silage (FFS) on serum biochemical parameters of Japanese quails (Coturnix coturnix japonica). MATERIALS AND METHODS: A total of 192, 7-day-old broiler Japanese quail chicks of either sex, were randomly distributed into four dietary treatments with four replicates in each group having 12 chicks in each replicate pen. The dietary treatments were T1 - Control diet, T2 - Diet containing 5% FFS, T3 - Diet containing 10% FFS, and T4 - Diet containing 15% FFS...
April 2017: Veterinary World
https://www.readbyqxmd.com/read/28506118/effect-of-a-diet-enriched-with-fresh-coconut-saturated-fats-on-plasma-lipids-and-erythrocyte-fatty-acid-composition-in-normal-adults
#8
Rokkam Shankar Nagashree, N K Manjunath, M Indu, M Ramesh, V Venugopal, P Sreedhar, N Pavithra, Hongasandra R Nagendra
OBJECTIVE: The objective of this study was to compare the effects of increased saturated fatty acid (SFA) (provided by fresh coconut) versus monounsaturated fatty acid (MUFA) intake (provided by a combination of groundnuts and groundnut oil) on plasma lipids and erythrocyte fatty acid (EFA) composition in healthy adults. MATERIAL AND METHODS: Fifty-eight healthy volunteers, randomized into 2 groups, were provided standardized diet along with 100 g fresh coconut or groundnuts and groundnut oil combination for 90 days in a Yoga University...
May 16, 2017: Journal of the American College of Nutrition
https://www.readbyqxmd.com/read/28504636/-eggs-do-not-increase-the-risk-of-cardiovascular-disease-and-can-be-safely-consumed
#9
Nina Rica Wium Geiker, Mogens Lytken Larsen, Jørn Dyerberg, Steen Stender, Arne Astrup
Eggs are nutrient dense, rich in essential amino- and fatty acids, and the most cholesterol containing food. Based on observational studies the consumption of eggs has since the 1970's been claimed to increase the risk of cardiovascular disease (CVD). Intervention studies on intake of eggs and plasma cholesterol do however not support causality. The higher incidence of CVD in egg eaters is more likely to be caused by the clustering of other CVD risk factors. Up to seven eggs per week can safely be consumed but in patients with CVD or diabetes only with special emphasis on a prudent diet and proper medical treatment...
May 15, 2017: Ugeskrift for Laeger
https://www.readbyqxmd.com/read/28503828/birthweight-and-cardiovascular-risk-factors-in-a-japanese-general-population
#10
Shinji Katsuragi, Tomonori Okamura, Yoshihiro Kokubo, Tomoaki Ikeda, Yoshihiro Miyamoto
AIM: This study was conducted to examine whether babies born small develop cardiovascular problems in later life. METHODS: Data were examined retrospectively for 1241 city dwellers (men 521, women 720) aged 40-69 years who received a medical examination at a single institution. Blood tests, physical measurements, and a questionnaire survey regarding birth weight (small, medium, large), medication history and lifestyle (alcohol consumption, smoking, exercise) was administered...
May 15, 2017: Journal of Obstetrics and Gynaecology Research
https://www.readbyqxmd.com/read/28503432/nutrient-patterns-and-risk-of-cataract-a-case-control-study
#11
Fatemeh Sedaghat, Matin Ghanavati, Parisa Nezhad Hajian, Sara Hajishirazi, Mehdi Ehteshami, Bahram Rashidkhani
AIM: To assess the relation between nutrient patterns and cataract risk. METHODS: This is a hospital-based case-control study with 97 cataract patients and 198 matched controls. Dietary consumption was collected through a valid food frequency questionnaire (FFQ). Nutrient patterns were detected by applying factor analysis. Unconditional logistic regression models were used to estimate odds ratio (ORs) and 95%CIs. RESULTS: We extracted 5 main nutrient patterns...
2017: International Journal of Ophthalmology
https://www.readbyqxmd.com/read/28502493/the-effect-of-maximal-vs-submaximal-exertion-on-postprandial-lipid-levels-in-individuals-with-and-without-coronary-heart-disease
#12
David M Aronov, Marina G Bubnova, Natalia V Perova, Alexander N Orekhov, Yuri V Bobryshev
BACKGROUND: Decisions about fat consumption and levels of physical activity are among the everyday choices we make in life and risk of coronary heart disease (CHD) can be affected by those choices. OBJECTIVE: The purpose of this study was to investigate the influence of a standard fat load combined with physical exertion of different intensities on the plasma lipid profile of CHD patients and CHD-free individuals. METHODS: This study looked at the influence of different intensities of physical exercise on postprandial lipid metabolism in 20 healthy men and 36 men with diagnosis of CHD...
March 2017: Journal of Clinical Lipidology
https://www.readbyqxmd.com/read/28501922/sepp1-polymorphisms-modulate-serum-glucose-and-lipid-response-to-brazil-nut-supplementation
#13
Janaina L S Donadio, Marcelo M Rogero, Elvira M Guerra-Shinohara, Charles Desmarchelier, Patrick Borel, Silvia M F Cozzolino
PURPOSE: The consumption of Brazil nuts has been associated with benefits to lipid metabolism and reductions in total cholesterol and LDL concentrations. They are the richest natural source of selenium which has essential functions in human physiology. Genetic polymorphisms in Selenoprotein P could impair lipid and glucose metabolisms. The aim of this work was to verify the influence of polymorphisms in genes for selenoproteins on blood lipid levels after dietary supplementation with Brazil nuts in healthy adults...
May 13, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28501660/alcohol-consumption-high-density-lipoprotein-cholesterol-antithrombin-iii-and-body-mass-index-are-associated-with-great-saphenous-vein-reflux-in-the-thigh
#14
Hyeonseung Kim, Hyangkyoung Kim, Je Hoon Park, Yong Han Kim, Sung Jin Oh, Byoung Jo Suh, Jong Kwon Park
OBJECTIVES: Venous valvular reflux is the main cause of chronic venous dysfunction. However, the etiology of valvular reflux is not completely understood. We conducted this study to investigate new risk factors for venous reflux of the great saphenous vein (GSV) in the thigh. METHODS: We studied 139 consecutive patients (278 legs) who underwent Doppler ultrasonography at our hospital between March 2015 and February 2016 for leg discomfort with visible varicosities, edema, skin changes, or venous ulcer in the legs...
May 10, 2017: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/28495678/sphingolipid-metabolic-flow-controls-phosphoinositide-turnover-at-the-trans-golgi-network
#15
Serena Capasso, Lucia Sticco, Riccardo Rizzo, Marinella Pirozzi, Domenico Russo, Nina A Dathan, Felix Campelo, Josse van Galen, Maarit Hölttä-Vuori, Gabriele Turacchio, Angelika Hausser, Vivek Malhotra, Isabelle Riezman, Howard Riezman, Elina Ikonen, Chiara Luberto, Seetharaman Parashuraman, Alberto Luini, Giovanni D'Angelo
Sphingolipids are membrane lipids globally required for eukaryotic life. The sphingolipid content varies among endomembranes with pre- and post-Golgi compartments being poor and rich in sphingolipids, respectively. Due to this different sphingolipid content, pre- and post-Golgi membranes serve different cellular functions. The basis for maintaining distinct subcellular sphingolipid levels in the presence of membrane trafficking and metabolic fluxes is only partially understood. Here, we describe a homeostatic regulatory circuit that controls sphingolipid levels at the trans-Golgi network (TGN)...
May 10, 2017: EMBO Journal
https://www.readbyqxmd.com/read/28493856/cdc-grand-rounds-public-health-strategies-to-prevent-and-treat-strokes
#16
Mary G George, Leah Fischer, Walter Koroshetz, Cheryl Bushnell, Michael Frankel, Jennifer Foltz, Phoebe G Thorpe
Worldwide, stroke is the second leading cause of death and a leading cause of serious long-term disability. In the United States, nearly 800,000 strokes occur each year; thus stroke is the fifth leading cause of death overall and the fourth leading cause of death among women (1). Major advances in stroke prevention through treatment of known risk factors has led to stroke being considered largely preventable. For example, in the United States, stroke mortality rates have declined 70% over the past 50 years, in large part because of important reductions in hypertension, tobacco smoking, and more recently, increased use of anticoagulation for atrial fibrillation (2,3)...
May 12, 2017: MMWR. Morbidity and Mortality Weekly Report
https://www.readbyqxmd.com/read/28488130/fish-consumption-intake-of-fats-and-cognitive-decline-at-middle-and-older-age-the-doetinchem-cohort-study
#17
Astrid C J Nooyens, Boukje M van Gelder, H Bas Bueno-de-Mesquita, Martin P J van Boxtel, W M Monique Verschuren
PURPOSE: To get insight in the impact of fish and fat intake in the prevention of accelerated cognitive decline with ageing, we tested associations between fish and different fat intakes and 5-year change in cognitive functions. METHODS: In 2612 men and women of the Doetinchem Cohort Study, aged 43-70 years at baseline, dietary intake (including fish consumption) and cognitive function were assessed at baseline and at 5-year follow-up. Average fish consumption (frequency) and intakes (as energy percentages) of total fat, saturated, mono unsaturated, and polyunsaturated fatty acids (PUFA), linoleic, docosahexaenoic, eicosapentaenoic, and a-linolenic acid (ALA), and cholesterol were averaged over baseline and follow-up...
May 9, 2017: European Journal of Nutrition
https://www.readbyqxmd.com/read/28487438/the-niemann-pick-c1-gene-interacts-with-a-high-fat-diet-to-promote-weight-gain-through-differential-regulation-of-central-energy-metabolism-pathways
#18
Joseph J Castillo, David Jelinek, Hao Wei, Nicholas P Gannon, Roger A Vaughan, L John Horwood, F John Meaney, Randi Garcia-Smith, Kristina A Trujillo, Randall A Heidenreich, David Meyre, Robert A Orlando, Renee C LeBoeuf, William S Garver
A genome-wide association study (GWAS) reported that common variation in the human Niemann-Pick C1 gene (NPC1) is associated with morbid adult obesity. This study was confirmed using our BALB/cJ Npc1 mouse model, whereby heterozygous mice (Npc1(+/-)) with decreased gene dosage were susceptible to weight gain when fed a high-fat diet (HFD) compared to homozygous normal mice (Npc1(+/+)) fed the same diet. The objective for our current study was to validate this Npc1 gene-diet interaction using statistical modeling with fitted growth trajectories, conduct body weight analyses for different measures, and define the physiological basis responsible for weight gain...
May 9, 2017: American Journal of Physiology. Endocrinology and Metabolism
https://www.readbyqxmd.com/read/28484502/improved-lipid-profile-associated-with-daily-consumption-of-tri-sura-phon-in-healthy-overweight-volunteers-an-open-label-randomized-controlled-trial
#19
Sirigoon Kuamsub, Pariyaphat Singthong, Wipawee Chanthasri, Nicharee Chobngam, Warissara Sangkaew, Sasithorn Hemdecho, Thammarat Kaewmanee, Sasitorn Chusri
Tri-Sura-Phon (TSP), a traditional Thai polyherbal formula renowned for its rejuvenating properties, is commonly used as a blood tonic. It comprises Cinnamomum bejolghota, Cinnamomum parthenoxylon, and Aquilaria crassna. The aim of this study is to evaluate the beneficial properties of TSP tea consumption on blood glucose regulation and serum lipid profiles of healthy overweight volunteers. This open-label, randomized controlled trial was conducted in 70 healthy overweight adults. Two groups of 35 subjects took a TSP infusion or a placebo (cornstarch) twice daily for 8 weeks...
2017: Evidence-based Complementary and Alternative Medicine: ECAM
https://www.readbyqxmd.com/read/28475799/role-of-fruits-and-vegetables-in-adolescent-cardiovascular-health-a-systematic-review
#20
Tatiana Sadalla Collese, Marcus Vinicius Nascimento-Ferreira, Augusto César Ferreira de Moraes, Tara Rendo-Urteaga, Silvia Bel-Serrat, Luis A Moreno, Heráclito Barbosa Carvalho
Context: Levels of fruit and vegetable consumption are low among adolescents, and the possible effect of this on cardiovascular health in this age group is undefined. Objective: The aim of this systematic review was to investigate the potential role of fruit and vegetable consumption in adolescent cardiovascular health. Data Sources: Six electronic databases (BioMed Central, MEDLINE, Web of Science, CINAHL, Scopus, PsycINFO) were searched from database inception to December 2015...
May 1, 2017: Nutrition Reviews
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