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https://www.readbyqxmd.com/read/28927908/the-impact-of-the-standard-american-diet-in-rats-effects-on-behavior-physiology-and-recovery-from-inflammatory-injury
#1
Stacie K Totsch, Tammie L Quinn, Larissa J Strath, Laura J McMeekin, Rita M Cowell, Barbara A Gower, Robert E Sorge
BACKGROUND AND AIMS: Obesity is a significant health concern in the Western world and the presence of comorbid conditions suggests an interaction. The overlapping distributions of chronic pain populations and obesity suggests that an interaction may exist. Poor quality diet (high carbohydrates, saturated fats, omega-6 polyunsaturated fatty acids) can lead to increased adiposity which can activate immune cells independent of the activating effect of the diet components themselves. This dual action can contribute to chronic inflammation that may alter susceptibility to chronic pain and prolong recovery from injury...
September 16, 2017: Scandinavian Journal of Pain
https://www.readbyqxmd.com/read/28919371/perinatal-deficiency-in-dietary-omega-3-fatty-acids-potentiates-sucrose-reward-and-diet-induced-obesity-in-mice
#2
Stéphanie Auguste, Sandeep Sharma, Alexandre Fisette, Caroline Daneault, Christine Des Rosiers, Stephanie Fulton
Insufficient dietary intake of essential omega-3 polyunsaturated fatty acids (N-3), especially during critical stages of development, is well-associated with negative neurological and metabolic consequences. The increased availability and intake of foods rich in saturated fat coincides with reduced N-3 consumption, yet how N-3 dietary deficiency during perinatal development modulates motivation for palatable food and interacts with a high-fat diet to affect body weight and emotional states is not clear. Pregnant C57Bl6 mice and pups were subjected to diets either deficient or adequate (control) in N-3 until postnatal day 21...
September 14, 2017: International Journal of Developmental Neuroscience
https://www.readbyqxmd.com/read/28919254/palmitic-acid-stimulates-energy-metabolism-and-inhibits-insulin-pi3k-akt-signaling-in-differentiated-human-neuroblastoma-cells-the-role-of-mtor-activation-and-mitochondrial-ros-production
#3
Erika Calvo-Ochoa, Karina Sánchez-Alegría, Cecilia Gómez-Inclán, Patricia Ferrera, Clorinda Arias
The high consumption of saturated lipids has been largely associated with the increasing prevalence of metabolic diseases. In particular, saturated fatty acids such as palmitic acid (PA) have been implicated in the development of insulin resistance in peripheral tissues. However, how neurons develop insulin resistance in response to lipid overload is not fully understood. Here, we used cultured rat cortical neurons and differentiated human neuroblastoma cells to demonstrate that PA blocks insulin-induced metabolic activation, inhibits the activation of the insulin/PI3K/Akt pathway and activates mTOR kinase downstream of Akt...
September 15, 2017: Neurochemistry International
https://www.readbyqxmd.com/read/28911936/exercise-training-in-patients-with-pulmonary-and-systemic-hypertension-a-unique-therapy-for-two-different-diseases
#4
REVIEW
Massimo Leggio, Augusto Fusco, Giorgio Limongelli, Luca Sgorbini
Pulmonary hypertension is a potentially life-threatening condition. Given its evolving definition, the incidence and prevalence of the disease is difficult to define, but registries suggest an increased global awareness. The management of patients with pulmonary arterial hypertension is highly specialised and requires multi-disciplinary input from a range of healthcare professionals, including cardiologists, respiratory physicians, rheumatologists, rehabilitation physicians and cardio-pulmonary physiotherapists...
September 11, 2017: European Journal of Internal Medicine
https://www.readbyqxmd.com/read/28905141/insights-into-the-simultaneous-utilization-of-glucose-and-glycerol-by-streptomyces-albulus-m-z18-for-high-%C3%AE%C2%B5-poly-l-lysine-productivity
#5
Xin Zeng, Junjie Zhao, Xusheng Chen, Zhonggui Mao, Wenyun Miao
The simultaneous consumption of glucose and glycerol led to remarkably higher productivity of both biomass and ε-poly-L-lysine (ε-PL), which was of great significance in industrial microbial fermentation. To further understand the superior fermentation performances, transcriptional analysis and exogenous substrates addition were carried out to study the simultaneous utilization of glucose and glycerol by Streptomyces albulus M-Z18. Transcriptome analysis revealed that there was no mutual transcriptional suppression between the utilization of glucose and glycerol, which was quite different from typical "glucose effect"...
September 13, 2017: Bioprocess and Biosystems Engineering
https://www.readbyqxmd.com/read/28898272/iron-deficiency-was-not-the-major-cause-of-anemia-in-rural-women-of-reproductive-age-in-sidama-zone-southern-ethiopia-a-cross-sectional-study
#6
Tafere Gebreegziabher, Barbara J Stoecker
BACKGROUND: Anemia, which has many etiologies, is a moderate/severe public health problem in young children and women of reproductive age in many developing countries. The aim of this study was to investigate prevalence of iron deficiency, anemia, and iron deficiency anemia using multiple biomarkers and to evaluate their association with food insecurity and food consumption patterns in non-pregnant women from a rural area of southern Ethiopia. METHODS: A cross-sectional study was conducted in 202 rural women of reproductive age in southern Ethiopia...
2017: PloS One
https://www.readbyqxmd.com/read/28892859/assessment-of-flushing-methods-for-the-removal-of-heavy-chlorinated-compounds-dnapl-in-an-alluvial-aquifer
#7
Julien Maire, Antoine Joubert, Delphine Kaifas, Thomas Invernizzi, Julien Marduel, Stéfan Colombano, David Cazaux, Cédric Marion, Pierre-Yves Klein, Alain Dumestre, Nicolas Fatin-Rouge
Immiscible mobilization and foam flushing were assessed as low surfactant consuming technologies, for the enhanced recovery of dense non-aqueous phase liquid (DNAPL) residual at a site contaminated by heavy chlorinated compounds. Preliminary experiments in well-controlled conditions demonstrated the phenomena involved in these remediation technologies and their limitations. Furthermore, we characterized the technologies according to by their surfactant consumption (per kg of DNAPL recovered) and the final DNAPL saturation reached...
September 7, 2017: Science of the Total Environment
https://www.readbyqxmd.com/read/28889206/dietary-fatty-acid-composition-modulates-obesity-and-interacts-with-obesity-related-genes
#8
REVIEW
Shatha S Hammad, Peter J Jones
The prevalence of obesity is skyrocketing worldwide. The scientific evidence has associated obesity risk with many independent factors including the quality of dietary fat and genetics. Dietary fat exists as the main focus of dietary guidelines targeting obesity reduction. To prevent/minimize the adipogenic effect of dietary fatty acids (FA), intakes of long-chain saturated- and trans-FA should be reduced and substituted with unsaturated FA. The optimal proportions of dietary unsaturated FA are yet to be defined, along with a particular emphasis on the need to achieve a balanced ratio of n-3:n-6 polyunsaturated FA and to increase monounsaturated FA consumption at the expense of saturated FA...
September 9, 2017: Lipids
https://www.readbyqxmd.com/read/28884114/the-mediterranean-diet-reduces-the-risk-and-mortality-of-the-prostate-cancer-a-narrative-review
#9
REVIEW
Cristiano Capurso, Gianluigi Vendemiale
Prostate cancer is the second most common cancer in the world among men, and is the fifth most common cause of cancer death among men. The aim of our review was to analyze observational and case-control studies to point out the effects of overweight and diets components on the cancer risk, particularly on risk of prostate cancer, and the effect of the Mediterranean diet (MD) on the reduction of risk and mortality of prostate cancer. It is known that incidence and progression of cancer is multifactorial. Cancer of the large bowel, breast, endometrium, and prostate are due also to a high body mass index and to high consumption of high carcinogenic dietary factors, as red and processed meat or saturated fats rich foods, and to a low consumption of vegetables and fruits...
2017: Frontiers in Nutrition
https://www.readbyqxmd.com/read/28879825/changes-in-consumption-of-food-away-from-home-and-intakes-of-energy-and-other-nutrients-among-us-working-age-adults-2005-2014
#10
Jessica E Todd
OBJECTIVE: To document changes in consumption of food away from home (FAFH) and intakes of selected nutrients by working-age adults between 2005-06 and 2013-14, covering the most recent recessionary period and recovery. DESIGN: Means were compared across survey rounds relative to 2005-06. Multivariate regression was used to account for changes in demographic characteristics over time. SETTING: National Health and Nutrition Examination Survey (NHANES), 2005-2014...
September 7, 2017: Public Health Nutrition
https://www.readbyqxmd.com/read/28876405/oxygen-saturation-and-lactate-concentration-gradient-from-the-right-atrium-to-the-pulmonary-artery-in-the-immediate-postoperative-following-cardiac-surgery-with-extracorporeal-circulation
#11
Juan Carlos Pendino, Leonardo Hess, Sergio Beltrame, Gonzalo Aldamiz-Echevarría Castillo, John Trujillo
Objective: This prospective study aimed to characterize the changes in blood lactate concentration and blood oxygen saturation in patients during the immediate postoperative period of cardiac surgery with extracorporeal circulation. Methods: Blood samples were collected from 35 patients in a rapid and random order from the arterial line and from the proximal and distal port of a pulmonary artery catheter. Results: The results showed no statistically significant differences between the blood oxygen saturation in the right atrium (72% ± 0...
September 4, 2017: Revista Brasileira de Terapia Intensiva
https://www.readbyqxmd.com/read/28864332/associations-of-fats-and-carbohydrate-intake-with-cardiovascular-disease-and-mortality-in-18-countries-from-five-continents-pure-a-prospective-cohort-study
#12
Mahshid Dehghan, Andrew Mente, Xiaohe Zhang, Sumathi Swaminathan, Wei Li, Viswanathan Mohan, Romaina Iqbal, Rajesh Kumar, Edelweiss Wentzel-Viljoen, Annika Rosengren, Leela Itty Amma, Alvaro Avezum, Jephat Chifamba, Rafael Diaz, Rasha Khatib, Scott Lear, Patricio Lopez-Jaramillo, Xiaoyun Liu, Rajeev Gupta, Noushin Mohammadifard, Nan Gao, Aytekin Oguz, Anis Safura Ramli, Pamela Seron, Yi Sun, Andrzej Szuba, Lungiswa Tsolekile, Andreas Wielgosz, Rita Yusuf, Afzal Hussein Yusufali, Koon K Teo, Sumathy Rangarajan, Gilles Dagenais, Shrikant I Bangdiwala, Shofiqul Islam, Sonia S Anand, Salim Yusuf
BACKGROUND: The relationship between macronutrients and cardiovascular disease and mortality is controversial. Most available data are from European and North American populations where nutrition excess is more likely, so their applicability to other populations is unclear. METHODS: The Prospective Urban Rural Epidemiology (PURE) study is a large, epidemiological cohort study of individuals aged 35-70 years (enrolled between Jan 1, 2003, and March 31, 2013) in 18 countries with a median follow-up of 7·4 years (IQR 5·3-9·3)...
August 28, 2017: Lancet
https://www.readbyqxmd.com/read/28853462/onsite-cavity-enhanced-raman-spectrometry-for-the-investigation-of-gas-exchange-processes-in-the-earth-s-critical-zone
#13
Anne Sieburg, Tobias Jochum, Susan E Trumbore, Jürgen Popp, Torsten Frosch
Raman gas spectrometry is introduced as a robust, versatile method for onsite, battery-powered field measurements of gases in the unsaturated and saturated critical zone. In this study, depth-profiles of the concentrations of oxygen and carbon dioxide were simultaneously monitored down to ∼70 meters depth in the subsurface via a transect of drilling holes located in the Hainich Critical Zone Exploratory in central Germany. A special multichannel monitoring system was designed to access and analyze these gases non-consumptively onsite in a closed loop measurement cycle...
August 30, 2017: Analyst
https://www.readbyqxmd.com/read/28840546/obstructive-sleep-apnea-does-not-impair-cardiorespiratory-responses-to-progressive-exercise-performed-until-exhaustion-in-hypertensive-elderly
#14
Bruno Teixeira Barbosa, Amilton da Cruz Santos, Murillo Frazão, Tulio Rocha Petrucci, Gabriel Grizzo Cucato, Adriana Oliveira Sarmento, Eduardo D S Freitas, Anna Myrna Jaguaribe de Lima, Maria do Socorro Brasileiro-Santos
BACKGROUND: Elderly people have a high prevalence to systemic arterial hypertension (SAH) and obstructive sleep apnea (OSA). Both comorbidities are closely associated and inflict damage on cardiorespiratory capacity. METHODS: In order to assess cardiorespiratory responses to the cardiopulmonary exercise test (CPET) among hypertensive elderly with OSA, we enrolled 28 subjects into two different groups: without OSA (No-OSA: apnea/hypopnea index (AHI) < 5 events/h; n = 15) and with OSA (OSA: AHI ≥ 15 events/h; n = 13)...
August 24, 2017: Sleep & Breathing, Schlaf & Atmung
https://www.readbyqxmd.com/read/28839010/circulatory-mechanisms-underlying-adaptive-increases-in-thermogenic-capacity-in-high-altitude-deer-mice
#15
Kevin B Tate, Catherine M Ivy, Jonathan P Velotta, Jay F Storz, Grant B McClelland, Zachary A Cheviron, Graham R Scott
We examined the circulatory mechanisms underlying adaptive increases in thermogenic capacity in deer mice (Peromyscus maniculatus) native to the cold hypoxic environment at high altitudes. Deer mice from high- and low-altitude populations were born and raised in captivity to adulthood, and then acclimated to normoxia or hypobaric hypoxia (simulating hypoxia at ∼4300 m). Thermogenic capacity (maximal O2 consumption, VO2max, during cold exposure) was measured in hypoxia, along with arterial O2 saturation (SaO2) and heart rate (fH)...
August 24, 2017: Journal of Experimental Biology
https://www.readbyqxmd.com/read/28838765/adherence-to-the-mediterranean-dietary-pattern-and-incidence-of-nephrolithiasis-in-the-seguimiento-universidad-de-navarra-follow-up-sun-cohort
#16
Alessandro Leone, Alejandro Fernández-Montero, Carmen de la Fuente-Arrillaga, Miguel Ángel Martínez-González, Simona Bertoli, Alberto Battezzati, Maira Bes-Rastrollo
BACKGROUND: Diet plays an important role in the pathogenesis of nephrolithiasis. Limited data are available to investigate the association between a Mediterranean dietary pattern and risk for nephrolithiasis. STUDY DESIGN: Prospective cohort study. SETTING & PARTICIPANTS: 16,094 men and women without a history of nephrolithiasis who participated in the Seguimiento Universidad de Navarra Follow-up (SUN) Project. PREDICTORS: A validated 136-item food frequency questionnaire was used to assess baseline adherence to a Mediterranean dietary pattern that is high in fruits, vegetables, nuts, fish, and legumes, but moderate in alcohol and low in meats, saturated fats, and sugars...
August 22, 2017: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/28837090/a-vote-for-school-lunches-school-lunches-provide-superior-nutrient-quality-than-lunches-obtained-from-other-sources-in-a-nationally-representative-sample-of-us-children
#17
Jacqueline A Vernarelli, Brady O'Brien
Childhood obesity is an ongoing public health program. As such, a major public health research objective is to identify potential targets for intervention; one such area is school lunches (SL). The National School Lunch Program (NSLP) serves over 31 million children each day; the National Health and Nutrition Examination Survey (NHANES) is uniquely positioned to allow researchers to assess diet quality in federal nutrition assistance programs. The objective of the study was to investigate whether lunches provided by schools provide different nutritional value than lunches obtained elsewhere...
August 24, 2017: Nutrients
https://www.readbyqxmd.com/read/28834795/microvascular-reactivity-monitored-with-near-infrared-spectroscopy-is-impaired-after-induction-of-anaesthesia-in-cardiac-surgery-patients-an-observational-study
#18
Lien Vandenbulcke, Koen G Lapage, Katrien V Vanderstraeten, Filip M De Somer, Stefan G De Hert, Annelies T Moerman
BACKGROUND: Induction of anaesthesia causes significant macrohaemodynamic changes, but little is known about its effects on the microcirculation. However, alterations in microvascular perfusion are known to be associated with impaired tissue oxygenation and organ dysfunction. Microvascular reactivity can be assessed with vascular occlusion testing, which evaluates the response of tissue oxygen saturation to transient ischaemia and reperfusion. OBJECTIVE: The aim of the current study was to evaluate the effects of an opioid-based anaesthesia induction on microvascular reactivity...
August 23, 2017: European Journal of Anaesthesiology
https://www.readbyqxmd.com/read/28834784/determination-of-fat-content-in-chicken-hamburgers-using-nir-spectroscopy-and-the-successive-projections-algorithm-for-interval-selection-in-pls-regression-ispa-pls
#19
Gabriela Krepper, Florencia Romeo, David Douglas de Sousa Fernandes, Paulo Henrique Gonçalves Dias Diniz, Mário César Ugulino de Araújo, María Susana Di Nezio, Marcelo Fabián Pistonesi, María Eugenia Centurión
Determining fat content in hamburgers is very important to minimize or control the negative effects of fat on human health, effects such as cardiovascular diseases and obesity, which are caused by the high consumption of saturated fatty acids and cholesterol. This study proposed an alternative analytical method based on Near Infrared Spectroscopy (NIR) and Successive Projections Algorithm for interval selection in Partial Least Squares regression (iSPA-PLS) for fat content determination in commercial chicken hamburgers...
August 17, 2017: Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
https://www.readbyqxmd.com/read/28819317/intradialytic-central-venous-oxygen-saturation-is-associated-with-clinical-outcomes-in-hemodialysis-patients
#20
Lili Chan, Hanjie Zhang, Anna Meyring-Wösten, Israel Campos, Doris Fuertinger, Stephan Thijssen, Peter Kotanko
Central venous oxygen saturation (ScvO2) in the superior vena cava is predominantly determined by cardiac output, arterial oxygen content, and oxygen consumption by the upper body. While abnormal ScvO2 levels are associated with morbidity and mortality in non-uremic populations, ScvO2 has received little attention in hemodialysis patients. From 1/2012 to 8/2015, 232 chronic hemodialysis patients with central venous catheters as vascular access had their ScvO2 monitored during a 6-month baseline period and followed for up to 36 months...
August 17, 2017: Scientific Reports
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