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Nicola Zingaretti, Fabrizio De Biasio, Francesca De Lorenzi, Samuele Massarut, Pier Camillo Parodi
Background: Symmastia is a medial confluence of the breasts, produced by a web of skin and fat merged across the midline, that generates the disappearance of the intermammary sulcus. Apart from the rare congenital cases, this condition is usually a result of technical complications during breast augmentation surgery.This article describes a simple and reliable method for correcting symmastia. Methods: From November 2006 to June 2015, we treated 10 patients with acquired symmastia who had previously undergone an implant-based reconstruction...
May 2018: Annals of Medicine and Surgery
Cuong Huynh, Anneke A Veenstra
Two new penicillate millipede species from the genera Unixenus and Monographis (Diplopoda, Polyxenidae) were collected from Phu Quoc Island, Vietnam's largest island. Unixenus intragramineus sp. n. was found within the stem of a creeping grass growing on an unstable, sandy substrate in the intertidal zone. The defining taxonomic characteristics of the genus Unixenus were apparent in U. intragramineus sp. n., but it is distinctively different from all described species. Monographis phuquocensis sp. n. belongs to a group of Monographis species which have their antennal sensilla arranged in a crescent-shape; but the structure of the labrum and telotarsus observed in this new species differs from other described Monographis...
March 28, 2018: Zootaxa
Jin-Lin Wu, Liang Zhang, Jun-Tao Qiu, Cun-Tao Yu
OBJECTIVES: This study aimed to investigate the morphological characteristics of the dissected thoracic aorta and brachiocephalic arteries within the Chinese population. METHODS: A retrospective analysis of computed tomography scans of 387 patients with acute Type A aortic dissection was carried out. The dimensions of the thoracic aorta at multiple levels and other imaging characteristics were studied. RESULTS: The patients with a maximum diameter ≥55 mm accounted for less than one-third of the population...
April 24, 2018: Interactive Cardiovascular and Thoracic Surgery
Crescent Jicol, Michael J Proulx, Frank E Pollick, Karin Petrini
To overcome differences in physical transmission time and neural processing, the brain adaptively recalibrates the point of simultaneity between auditory and visual signals by adapting to audiovisual asynchronies. Here, we examine whether the prolonged recalibration process of passively sensed visual and auditory signals is affected by naturally occurring multisensory training known to enhance audiovisual perceptual accuracy. Hence, we asked a group of drummers, of non-drummer musicians and of non-musicians to judge the audiovisual simultaneity of musical and non-musical audiovisual events, before and after adaptation with two fixed audiovisual asynchronies...
April 23, 2018: Experimental Brain Research. Experimentelle Hirnforschung. Expérimentation Cérébrale
Gherardo Mannino, Rossella Guerini
RIASSUNTO. Al fine di comprendere meglio la psicopatologia del disturbo ossessivo-compulsivo (DOC), in anni recenti è stata prestata una crescente attenzione alla cosiddetta "paura di sé" (fear of self), vale a dire la paura che le persone con DOC nutrono di ospitare dentro di sé aspetti inaccettabili. Tuttavia, l'esatta dinamica di questo fenomeno ancora non è chiara: di conseguenza, allo scopo di delucidarla meglio, sarà qui descritto uno specifico processo psicologico denominato Identificazione Retrospettiva delle Motivazioni e delle Inclinazioni (IRMI)...
March 2018: Rivista di Psichiatria
Petr Smýkal, Oldřich Trněný, Jan Brus, Pavel Hanáček, Abhishek Rathore, Rani Das Roma, Vilém Pechanec, Martin Duchoslav, Debjyoti Bhattacharyya, Michalis Bariotakis, Stergios Pirintsos, Jens Berger, Cengiz Toker
[This corrects the article DOI: 10.1371/journal.pone.0194056.].
2018: PloS One
Yvonne T Kschonsak, Ingrid Hoffmann
Correct spindle orientation is achieved through signaling pathways that provide a molecular link between the cell cortex and spindle microtubules in an F-actin dependent manner. A conserved cortical protein complex, composed of LGN, NuMA, dynein-dynactin, plays a key role in establishing proper spindle orientation. It has also been shown that the actin-binding protein MISP and the ERM family, that are activated by LOK/SLK in mitosis, regulate spindle orientation. Here, we report that MISP functions between the ERM family member Ezrin and NuMA to allow optimal spindle positioning...
April 18, 2018: Journal of Cell Science
Dharmenaan Palamuthusingam, Clare Castledine, Sarah Lawman
Numerous studies have addressed the predictive value of pathology findings from the Oxford Classification. Whether this influences treatment choice has not been determined. We evaluated patients with IgA nephropathy who were immunosuppressed and correlated our findings with both clinical and histological features as per the Oxford Classification. This was a retrospective observational study of 45 patients who had biopsy-proven IgA nephropathy with a mean follow-up of 2.6 years. Primary outcomes were time to end-stage renal disease (ESRD) or a 50% rise in serum creatinine...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
Wael El-Reshaid, Kamel El-Reshaid, Shaikha Al-Bader, Ahmad Ramadan, John Patrick Madda
We report our experience of renal disease associated with bodybuilders who had been on high-protein diet, anabolic androgenic steroids (AASs), and growth hormone (GH) for years. A total of 22 adult males who volunteered information about use of high protein diet and AAS or GH were seen over a six-year period with renal disease. Kidney biopsy revealed focal segmental glomerulosclerosis (FSGS) in eight, nephroangiosclerosis in four, chronic interstitial nephritis in three, acute interstitial nephritis in two, nephrocalcinosis with chronic interstitial nephritis in two, and single patients with membranous glomerulopathy, crescentic glomerulopathy, and sclerosing glomerulonephritis...
March 2018: Saudi Journal of Kidney Diseases and Transplantation
Jumpei Hasegawa, Junichi Hoshino, Akinari Sekine, Noriko Hayami, Tatsuya Suwabe, Keiichi Sumida, Koki Mise, Toshiharu Ueno, Masayuki Yamanouchi, Ryo Hazue, Naoki Sawa, Kenichi Ohashi, Takeshi Fujii, Kenmei Takaichi, Yoshifumi Ubara
BACKGROUND: Antithyroid drugs such as propylthiouracil and methimazole have been reported to cause antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis (AAV), but little is known about long-term outcomes. MATERIALS AND METHODS: We identified AAV patients who underwent renal biopsy and retrospectively assessed their clinical and histological findings. Patients with AAV who had received propylthiouracil or methimazole were defined as having antithyroid drug-associated AAV (ATD-AAV), and the other patients were defined as having primary AAV...
April 12, 2018: Clinical Nephrology
Morakot Kaewthamasorn, Mika Takeda, Tawee Saiwichai, Jesse N Gitaka, Sonthaya Tiawsirisup, Yuhei Imasato, Ehab Mossaad, Ali Sarani, Winai Kaewlamun, Manun Channumsin, Suchart Chaiworakul, Wichit Katepongpun, Surapong Teeveerapunya, Jarus Panthong, Dominic K Mureithi, Saw Bawm, Lat Lat Htun, Mar Mar Win, Ahmed Ali Ismail, Abdalla Mohamed Ibrahim, Keisuke Suganuma, Hassan Hakimi, Ryo Nakao, Ken Katakura, Masahito Asada, Osamu Kaneko
Plasmodium was first identified in a goat in Angola in 1923, and only recently characterized by DNA isolation from a goat blood sample in Zambia. Goats were first domesticated in the Fertile Crescent approximately 10,000 years ago, and are now globally distributed. It is not known if the Plasmodium identified in African goats originated from parasites circulating in the local ungulates, or if it co-evolved in the goat before its domestication. To address this question, we performed PCR-based surveillance using a total of 1,299 goat blood samples collected from Sudan and Kenya in Africa, Iran in west Asia, and Myanmar and Thailand in southeast Asia...
April 11, 2018: Scientific Reports
Scott Watson, Benjamin Allen, Chris Robbins, Asheesh Bedi, Joel J Gagnier, Bruce Miller
Background: Limited literature exists regarding the influence of rotator cuff tear morphology on patient outcomes. Purpose: To determine the effect of rotator cuff tear pattern (crescent, U-shape, L-shape) on patient-reported outcomes after rotator cuff repair. Study Design: Cohort study; Level of evidence, 3. Methods: Patients undergoing arthroscopic repair of known full-thickness rotator cuff tears were observed prospectively at regular intervals from baseline to 1 year...
March 2018: Orthopaedic Journal of Sports Medicine
Hüsnü Tokgöz, Soner Yalçınkaya, Ekrem İslamoğlu, Kaan Karamık, Özlem Tokgöz, Murat Savaş
Objectives: We tried to investigate the effects of lunar phase on Shock Wave Lithotripsy (SWL) related pain. In addition, correlation of various clinical parameters with the pain perception during SWL procedure, were also investigated. Methods: A total of 378 patients who underwent first SWL sessions for renal or ureteral stones were prospectively enrolled in the study. The degree of pain perception during the procedure was evaluated with 10-point visual analog scale (VAS) and pain questionnaires...
December 2017: Ghana Medical Journal
Alexiane Schoettle, Francis Veillon, Aina Venkatasamy
No abstract text is available yet for this article.
April 3, 2018: Abdominal Radiology
Namık Şahin, Gökhan Cansabuncu, Nazan Çevik, Oğuz Türker, Güven Özkaya, Yüksel Özkan
OBJECTIVES: The aim of this study was to compare clinical and radiological results of proximal crescentic osteotomy (PCO) and rotational scarf osteotomy performed in the treatment of hallux valgus. METHODS: A total of 57 consecutive patients (60 feet) with symptomatic hallux valgus deformity were randomly assigned to one of two groups. The PCO group consisted of 22 women and 5 men (30 feet) and the mean age was 43(±14.5) years. The scarf group consisted of 23 women and 7 men (30 feet) and the mean age was 40...
March 30, 2018: Acta Orthopaedica et Traumatologica Turcica
Elizabeth A Waters, Eric V Shusta
Variable lymphocyte receptors (VLRs) are leucine-rich repeat proteins in jawless vertebrates that function similarly to Ig antibodies. However, VLRs possess a distinct crescent-shaped structure and modularity that results in a concave binding interface that contrasts significantly with Ig antibodies. Antigen binding interactions result in specific, high affinity VLR binding interactions with both proteins and glycans. The natural sourcing of VLRs allows for immunization strategies, while the modularity enables a whole host of protein engineering approaches including consensus scaffolds, designed libraries and directed evolution with display technologies...
March 26, 2018: Current Opinion in Biotechnology
Marenao Tanaka, Norihito Moniwa, Tomohiro Mita, Toshiyuki Tobisawa, Tamaki Matsumoto, Atsushi Mochizuki, Tomohisa Yamashita, Toshiyuki Yano, Masato Furuhashi, Tetsuji Miura
Systemic urticaria in a 64-year-old woman was diagnosed as leukocytoclastic vasculitis by a punch biopsy of the skin. Her physical findings improved after prescription of prednisolone at a dose of 20 mg/day, but the skin rash relapsed with renal dysfunction, proteinuria, and hematuria when the dose of prednisolone was reduced over a period of 9 months to 1 mg/day. She was admitted to our institute for further examination, when urinary protein and plasma creatinine levels were 0.8 g/day and 1.7 mg/dL, respectively...
September 2017: Case Reports in Nephrology and Dialysis
Gurinder Kumar, Alyaa Saeed Al Ali, Namrata Gulzar Bhatti
Rare bacteria can lead to infective endocarditis, which may lead to renal involvement as severe glomerulonephritis. We report our experience of a 12-year-old child who presented with infective endocarditis and blood culture-grown Gemella morbillorum - a rarely reported bacteria. The clinical picture was further complicated with severe glomerulonephritis. Renal biopsy was suggestive of crescentic glomerulonephritis. The child was managed with antibiotics, steroids, and plasmapheresis and responded well to the treatment...
September 2017: Case Reports in Nephrology and Dialysis
Maya Antoshvili, Ido Caspy, Michael Hippler, Nathan Nelson
The evolution of photosynthesis from primitive photosynthetic bacteria to higher plants has been driven by the need to adapt to a wide range of environmental conditions. The red alga Cyanidioschyzon merolae is a primitive organism, which is capable of performing photosynthesis in extreme acidic and hot environments. The study of its photosynthetic machinery may provide new insight on the evolutionary path of photosynthesis and on light harvesting and its regulation in eukaryotes. With that aim, the structural and functional properties of the PSI complex were investigated by biochemical characterization, mass spectrometry, and X-ray crystallography...
March 26, 2018: Photosynthesis Research
Petr Smýkal, Oldřich Trněný, Jan Brus, Pavel Hanáček, Abhishek Rathore, Rani Das Roma, Vilém Pechanec, Martin Duchoslav, Debjyoti Bhattacharyya, Michalis Bariotakis, Stergios Pirintsos, Jens Berger, Cengiz Toker
Knowledge of current genetic diversity and mating systems of crop wild relatives (CWR) in the Fertile Crescent is important in crop genetic improvement, because western agriculture began in the area after the cold-dry period known as Younger Dryas about 12,000 years ago and these species are also wild genepools of the world's most important food crops. Wild pea (Pisum sativum subsp. elatius) is an important source of genetic diversity for further pea crop improvement harbouring traits useful in climate change context...
2018: PloS One
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