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Farzaneh Montazerifar, Ahmad Bolouri, Raheleh Sharifian Paghalea, Mahbubeh Khodadadpour Mahani, Mansour Karajibani
Background: Clinical studies have demonstrated that adipocytokines play an important role in developing atherosclerotic cardiovascular diseases. Objective: The aim of study was to evaluate the relationship between serum resistin and leptin levels with obesity and coronary artery disease (CAD). Methods: In a cross-sectional study, we assessed the levels of serum resistin and leptin, C-reactive protein (CRP), lipid profile and cardiac enzyme tests (AST, CPK, LDH, CK-MB) in 40 CAD patients compared to 40 healthy controls...
September 12, 2016: Arquivos Brasileiros de Cardiologia
Ana Rodríguez-Valle, María Ángeles Navarro-Ferrando, Diana Boj-Carceller, Jesús Fernando Escanero-Marcén, Alejandro Sanz-Paris
Objetivo: poco se conoce sobre el impacto de orlistat en el sistema leptina. Estudiamos la respuesta de la leptina plasmática y la sensación de saciedad tras dos días de tratamiento con orlistat sin dieta hipocalórica ni pérdida de peso. Material y métodos: reclutamos veinte mujeres obesas en nuestras consultas externas de medicina. Habían recibido restricción dietética y modificación del estilo de vida, pero se habían mantenido obesas con peso corporal estable durante seis meses antes de su inclusión en el estudio...
2016: Nutrición Hospitalaria: Organo Oficial de la Sociedad Española de Nutrición Parenteral y Enteral
E Santos, A Rodríguez, C Prieto, M J Gil, G Frühbeck, J Quiroga, J I Herrero, J Salvador
BACKGROUND: There is a high prevalence of nutritional disorders in patients with liver cirrhosis (LC). This study was designed to assess the relationships between liver function, IFG-I/IGFBP-3, nutritional status, leptin, ghrelin and glucagon in 21 patients waiting for liver transplantation (LT). METHODS: We studied 21 men aged 56±2.1 years who were on the LT list. They were classified according to Child-Pugh(CP) score from low to high liver dysfunction in CPA (n=4),CPB (n=11) and CPC (n=6)...
2016: Anales del Sistema Sanitario de Navarra
Dealmy Delgadillo-Guzmán, Martha Angélica Quintanar-Escorza, Manuela de la A Carrera-Gracia, Ismael Lares-Aseff
BACKGROUND: Obesity is a multifactorial metabolic disorder that involves lipid peroxidation (LPX), activating the antioxidant systems to counteract cellular damage. Objective: To evaluate the correlation between the antioxidant capacity and LPX levels of /eptin, in indigenous Tepehuan and Mestizo populations of the State of Durango. METHODS: We conducted a nutritional clinical study and lipid profile to confirm the state of health of a group of 60 indigenous Tepehuan of Mezquital and 68 mestizos subjects of Durango city, aged between 18 to 59 years...
March 2015: Gaceta Médica de México
Amador Schüller Pérez
The obesity, serious frequenty sanitary problem, cause of complications that effects to the expectation of life, with aesthetic repercussion and with an increase in the last decades. Admitted the obesity android, gynoide, central or abdominal, wide aesthetic repercussion and physiopathologic like hyperdislipemias, metabolic alterations (diabetes mellitus, etc...), arterial hypertension, column arthrosis and outlying. Ethiopathologics co-factors, sedentariness, genotypic predisposition, endocrine alterations and of the leptina secretion...
2004: Anales de la Real Academia Nacional de Medicina
G Riccioni, V Menna, M S Lambo, R Della Vecchia, C Di Ilio, A De Lorenzo, N D'Orazio
The leptin system is a major regulator of food intake and metabolic rate. The leptin, an adipose tissue hormone whose plasma levels reflect energy stores, plays an important rule in the pathogenesis of such eating disorders like bulimia and anorexia. Thyroid hormones are major regulators of energy homeostasis. It is possible that leptin and thyroid hormone exert their actions on thermogenesis and energy metabolism via the same common effector patways. Leptin influences feedback regulation of the hypotalamic TRH-secreting neurons by thyroid hormone...
January 2004: La Clinica Terapeutica
G Riccioni, N D'Orazio, V Menna, M S Lambo, M T Guagnano, C Di Ilio
Anorexia and bulimia nervosa are the main psychiatric disorders characterised by abnormal models of feeding and perception of people's personal physical appearance and weight. These symptoms are associated with a severe psychosocial uneasiness that leads to severe medical complications and this, to its turn, has a big impact on morbidity and sick rate of general population. Although researchers have made big improvements in individualising some likely pathogenic mechanisms that include different factors (genetic, neurochemical and sociocultural) and psychological development, the pathogenesis of these kinds of feeding disorders is still unknown...
November 2003: La Clinica Terapeutica
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