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https://www.readbyqxmd.com/read/28048525/we-ab-207a-11-respiratory-motion-guided-4dcbct-a-step-towards-controlling-4dcbct-image-quality
#1
R O'Brien, U Stankovic, P Keall, J Sonke
PURPOSE: We have developed a method, called respiratory motion guided 4DCBCT (RMG-4DCBCT), in which the gantry speed and projection frequency are varied in response to the patient's real-time respiratory signal to eliminate streaking artifacts and to suppress duplicate projections in 4DCBCT images. In 2015, we realized RMG-4DCBCT on an Elekta Synergy linear accelerator with a mechanical relay to suppress projections and a potentiometer to adjust the gantry speed in response to the patient's real-time respiratory signal...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28048240/su-f-j-117-impact-of-motion-artifacts-on-image-quality-and-accuracy-of-tumor-motion-reconstruction-in-4d-ct-on-rails-and-mv-cbct-scans-a-phantom-study
#2
T Lin, C Ma
PURPOSE: To compare and quantify respiratory motion artifacts in images from free breathing 4D-CT-on-Rails(CTOR) and those from MV-Cone-beam-CT(MVCB) and facilitate respiratory motion guided radiation therapy. METHODS: 4D-CTOR: Siemens Somatom CT-on-Rails system with Anzai belt loaded with pressure sensor load cells. 4D scans were performed in helical mode, pitch 0.1, gantry rotation time 0.5s, 1.5mm slice thickness, 120kVp, 400 mAs. Normal and fast breathing (>12rpm) scanning protocols were investigated...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047532/th-ef-bra-05-a-method%C3%A3-of-near-real-time-4d-mri-using-volumetric-dynamic-keyhole-vdk-in-the-presence-of-respiratory-motion-for-mr-guided-radiotherapy
#3
B Lewis, S Kim, T Kim
PURPOSE: To develop a novel method that enables 4D MR imaging in near real-time for continuous monitoring of tumor motion in MR-guided radiotherapy. METHODS: This method is mainly based on an idea of expanding dynamic keyhole to full volumetric imaging acquisition. In the VDK approach introduced in this study, a library of peripheral volumetric k-space data is generated in given number of phases (5 and 10 in this study) in advance. For 4D MRI at any given time, only volumetric central k-space data are acquired in real-time and combined with pre-acquired peripheral volumetric k-space data in the library corresponding to the respiratory phase (or amplitude)...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28047456/mo-de-207a-06-ecg-gated-ct-reconstruction-for-a-c-arm-inverse-geometry-x-ray-system
#4
J M Slagowski, Dap Dunkerley
PURPOSE: To obtain ECG-gated CT images from truncated projection data acquired with a C-arm based inverse geometry fluoroscopy system, for the purpose of cardiac chamber mapping in interventional procedures. METHODS: Scanning-beam digital x-ray (SBDX) is an inverse geometry fluoroscopy system with a scanned multisource x-ray tube and a photon-counting detector mounted to a C-arm. In the proposed method, SBDX short-scan rotational acquisition is performed followed by inverse geometry CT (IGCT) reconstruction and segmentation of contrast-enhanced objects...
June 2016: Medical Physics
https://www.readbyqxmd.com/read/28027768/the-evolution-of-radiation-dose-over-time-measurement-of-a-patient-cohort-undergoing-whole-body-examinations-on-three-computer-tomography-generations
#5
Roy P Marcus, Elise Koerner, Roland C Aydin, Dominik Zinsser, Tobias Finke, Christian J Cyron, Fabian Bamberg, Konstantin Nikolaou, Mike Notohamiprodjo
OBJECTIVES: To evaluate and compare the radiation dose and image quality of whole-body-CT (WBCT) performed on the 3rd-generation dual-source-CT (DSCT) with 2nd-generation DSCT and 64-slices-Single-Source-CT (SSCT) in a large patient cohort. MATERIAL AND METHODS: Using a monitoring and tracking software 1451, 747 and 1861 patients scanned with a one-spiral-thorax-abdomen-pelvis-CT-examination on a 3rd-, 2nd-generation DSCT and SSCT, respectively, were extracted from the PACS server...
January 2017: European Journal of Radiology
https://www.readbyqxmd.com/read/28005510/case-237-renal-cell-carcinoma-with-osseous-metaplasia
#6
Billy Ming Hei Lai, Solomon Yig Joon Ka, Wai Kuen Kan, Man Wah Lam, Tang Fei Lee, Yun Hoi Lui, Jennifer Lai San Khoo
History A 47-year-old man presented with palpitations and decreased exercise tolerance. A peripheral blood smear revealed anemia, thrombocytopenia, and blast cells, and a diagnosis of acute myeloid leukemia was made. Immunohistochemistry revealed positivity for cluster of differentiation (or CD) markers, which have been reported to be associated with an increased risk of extramedullary leukemic involvement. Thus, contrast material-enhanced computed tomography (CT) of the thorax, abdomen, and pelvis was requested to enable exclusion of any extramedullary extension of leukemia...
January 2017: Radiology
https://www.readbyqxmd.com/read/27973925/a-reduced-gastric-corpus-microvascular-blood-flow-during-ivor-lewis-esophagectomy-detected-by-laser-speckle-contrast-imaging-technique
#7
Rikard Ambrus, Lars B Svendsen, Niels H Secher, Kim Rünitz, Hans-Jørgen Frederiksen, Morten B S Svendsen, Mette Siemsen, Steen C Kofoed, Michael P Achiam
BACKGROUND: Reduced microvascular blood flow is related to anastomotic insufficiency following esophagectomy, emphasizing a need for intraoperative monitoring of the microcirculation. This study evaluated if laser speckle contrast imaging (LSCI) was able to detect intraoperative changes in gastric microcirculation. METHODS: Gastric microcirculation was assessed prior to and after reconstruction of gastric continuity in 25 consecutive patients operated for adenocarcinoma with open Ivor-Lewis esophagectomy while hemodynamic variables were recorded...
December 15, 2016: Scandinavian Journal of Gastroenterology
https://www.readbyqxmd.com/read/27936890/incidental-findings-in-the-skeletal-musculature-on-computed-tomography
#8
Dominik Schramm, Annkathrin Justus, Andreas Gunter Bach, Alexey Surov
OBJECTIVE: The purpose of this study was to analyze intramuscular incidental findings identified on computed tomography (CT) in a large patients cohort. METHODS: In the time period from 2010 to 2015 a total of 44 794 patients with several diagnoses were investigated by CT. Only patients, who underwent body CT including the neck, thorax, abdomen and pelvic regions after intravenous application of contrast medium were involved in the study. There were 4085 patients...
December 12, 2016: British Journal of Radiology
https://www.readbyqxmd.com/read/27919724/reference-levels-for-central-venous-pressure-and-pulmonary-artery-occlusion-pressure-monitoring-in-the-lateral-position
#9
In-Kyung Song, Soohan Ro, Ji-Hyun Lee, Eun-Hee Kim, Hee-Soo Kim, Jae-Hyon Bahk, Jin-Tae Kim
OBJECTIVE: To investigate reference levels for central venous pressure or pulmonary artery occlusion pressure monitoring in a lateral position. DESIGN: Retrospective observational study. SETTING: A tertiary university hospital. PARTICIPANTS: A total of 204 adults who underwent chest computed tomography scan in the 90° lateral position from November 2006 to February 2015. INTERVENTIONS: None. MEASUREMENTS AND MAIN RESULTS: Distances from the mid-sternum to the uppermost and lowermost blood levels of both atria were measured...
September 13, 2016: Journal of Cardiothoracic and Vascular Anesthesia
https://www.readbyqxmd.com/read/27908174/respiratory-motion-compensation-for-simultaneous-pet-mr-based-on-highly-undersampled-mr-data
#10
Christopher M Rank, Thorsten Heußer, Andreas Wetscherek, Martin T Freitag, Oliver Sedlaczek, Heinz-Peter Schlemmer, Marc Kachelrieß
PURPOSE: Positron emission tomography (PET) of the thorax region is impaired by respiratory patient motion. To account for motion, the authors propose a new method for PET/magnetic resonance (MR) respiratory motion compensation (MoCo), which uses highly undersampled MR data with acquisition times as short as 1 min/bed. METHODS: The proposed PET/MR MoCo method (4D jMoCo PET) uses radial MR data to estimate the respiratory patient motion employing MR joint motion estimation and image reconstruction with temporal median filtering...
December 2016: Medical Physics
https://www.readbyqxmd.com/read/27894354/do-mosquitoes-transmit-the-avian-malaria-like-parasite-haemoproteus-an-experimental-test-of-vector-competence-using-mosquito-saliva
#11
Rafael Gutiérrez-López, Josué Martínez-de la Puente, Laura Gangoso, Jiayue Yan, Ramón C Soriguer, Jordi Figuerola
BACKGROUND: The life-cycle of many vector-borne pathogens includes an asexual replication phase in the vertebrate host and sexual reproduction in the insect vector. However, as only a small array of parasites can successfully develop infective phases inside an insect, few insect species are competent vectors for these pathogens. Molecular approaches have identified the potential insect vectors of blood parasites under natural conditions. However, the effectiveness of this methodology for verifying mosquito competence in the transmission of avian malaria parasites and related haemosporidians is still under debate...
November 28, 2016: Parasites & Vectors
https://www.readbyqxmd.com/read/27891001/rigid-bronchoscopic-management-of-acute-respiratory-failure-in-a-30-year-old-woman
#12
Karan Madan, Ashesh Dhungana, Neha Kawatra Madan, Anant Mohan, Vijay Hadda, Rakesh Garg, Deepali Jain, Randeep Guleria
A 30-year-old woman presented with a history of progressive shortness of breath, cough, and hoarseness. Stridor was audible on examination. Chest X-ray showed normal lung fields and contrast-enhanced computed tomography thorax showed lower tracheal occlusion with endoluminal growth. Diagnostic flexible bronchoscopy demonstrated multiple whitish glistening nodules over both vocal cords and lower tracheal occlusion by whitish nodular growth. In view of critical central airway obstruction, rigid bronchoscopy and excision of the lower tracheal growth were performed...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27880736/experimental-validation-of-a-multi-energy-x-ray-adapted-scatter-separation-method
#13
A Sossin, V Rebuffel, J Tabary, J M Létang, N Freud, L Verger
Both in radiography and computed tomography (CT), recently emerged energy-resolved x-ray photon counting detectors enable the identification and quantification of individual materials comprising the inspected object. However, the approaches used for these operations require highly accurate x-ray images. The accuracy of the images is severely compromised by the presence of scattered radiation, which leads to a loss of spatial contrast and, more importantly, a bias in radiographic material imaging and artefacts in CT...
December 21, 2016: Physics in Medicine and Biology
https://www.readbyqxmd.com/read/27845360/pathophysiological-mechanisms-underlying-phenotypic-differences-in-pulmonary-radioresponse
#14
Isabel L Jackson, Yuji Zhang, Søren M Bentzen, Jingping Hu, Angel Zhang, Zeljko Vujaskovic
Differences in the pathogenesis of radiation-induced lung injury among murine strains offer a unique opportunity to elucidate the molecular mechanisms driving the divergence in tissue response from repair and recovery to organ failure. Here, we utilized two well-characterized murine models of radiation pneumonitis/fibrosis to compare and contrast differential gene expression in lungs 24 hours after exposure to a single dose of whole thorax lung irradiation sufficient to cause minor to major morbidity/mortality...
November 15, 2016: Scientific Reports
https://www.readbyqxmd.com/read/27813098/four-cases-of-pulmonary-thromboembolism-diagnosed-by-endobronchial-ultrasound
#15
Onur Fevzi Erer, Pinar Cimen, Mehmet Unlu, Nuran Katgi
Endobronchial ultrasound (EBUS) is a technique for the detection of mediastinal abnormalities. A total of 548 EBUS procedures were performed for various indications, and in four cases (0.7%), filling defects in central pulmonary arteries were demonstrated fortuitously during the procedure. Subsequently, all patients underwent contrast-enhanced CT of the thorax to confirm the diagnosis of pulmonary thromboembolism (PTE). In three of the four cases, there was a concomitant lung cancer. PTE can be incidentally detected during EBUS; therefore, pulmonary arteries should be examined carefully during EBUS in all patients, particularly in patients with suspected or proven malignancy...
November 3, 2016: Journal of Clinical Ultrasound: JCU
https://www.readbyqxmd.com/read/27785331/congenital-esophageal-duplication-cyst-a-rare-cause-of-dysphagia-in-an-adult
#16
Nikhil Sonthalia, Samit S Jain, Ravindra G Surude, Ashok R Mohite, Pravin M Rathi
Esophageal duplication cyst is a rare congenital embryonal gastrointestinal (GI) malformation which is diagnosed most commonly in childhood. In adults, they can present with a variety of symptoms ranging from dysphagia, chest pain, epigastric discomfort, and vomiting to more serious complications including infections, hemorrhage, and ulcerations. A 30-year-old male presented with gradually progressive dysphagia to solids for 4 months without significant weight loss. Clinical examination and routine laboratory examination were unrevealing...
October 2016: Gastroenterology Research
https://www.readbyqxmd.com/read/27775076/multiplatform-based-molecular-subtypes-of-non-small-cell-lung-cancer
#17
F Chen, Y Zhang, E Parra, J Rodriguez, C Behrens, R Akbani, Y Lu, J M Kurie, D L Gibbons, G B Mills, I I Wistuba, C J Creighton
Non-small-cell lung cancer (NSCLC) demonstrates remarkable molecular diversity. With the completion of The Cancer Genome Atlas (TCGA), there is opportunity for systematic analyses of the entire TCGA NSCLC cohort, including comparisons and contrasts between different disease subsets. On the basis of multidimensional and comprehensive molecular characterization (including DNA methylation and copy, and RNA and protein expression), 1023 NSCLC cases-519 from TCGA adenocarcinoma (AD) project and 504 from TCGA squamous cell carcinoma (SQCC) project-were classified using a 'cluster-of-clusters' analytic approach...
October 24, 2016: Oncogene
https://www.readbyqxmd.com/read/27749415/incidental-sclerosing-pneumocytoma-detected-on-bone-scintigraphy
#18
Alex Cheen Hoe Khoo, Fadzilah Hamzah, Choo Khoon Ong
Nonosseous uptake in Tc-hydroxymethylene bone scintigraphy should always be evaluated for any possibility of pathological changes. We share interesting images of a 60-year-old woman initially investigated for suspected osteomyelitis of the left femur but found to have an extraosseous uptake in the right hemithorax on bone scintigraphy. Plain chest radiograph followed by contrast-enhanced CT of the thorax revealed the presence of a lung mass in the right lower lobe with no lymphadenopathy. CT-guided biopsy yielded fibrocollagenous tissue, partly lined by benign pneumocytes...
January 2017: Clinical Nuclear Medicine
https://www.readbyqxmd.com/read/27696307/optimal-transducer-level-for-atrial-and-pulmonary-arterial-pressure-measurement-in-patients-with-functional-single-ventricle
#19
Yong-Hee Park, Da-Hye Yoo, Eun-Hee Kim, In-Kyung Song, Ji-Hyun Lee, Hee-Soo Kim, Woong-Han Kim, Jin-Tae Kim
This study aimed to investigate the optimal transducer level for accurate measurement of atrial and pulmonary arterial pressures in the supine position for patients with functional single ventricle. Contrast-enhanced chest computed tomographic images of 108 patients who underwent either the bidirectional cavopulmonary shunt (BCPS) placement or the Fontan procedure were reviewed. Vertical distances from the skin of the back to the uppermost levels of fluid in the single atrium or the pulmonary artery confluence and their ratios to the greatest anteroposterior (AP) diameter of the thoracic cage were determined...
October 1, 2016: Pediatric Cardiology
https://www.readbyqxmd.com/read/27666805/endovascular-treatment-of-late-aortic-erosive-lesion-by-pedicle-screw-without-screw-removal-case-report-and-literature-review
#20
Antonio Eduardo Zerati, Dafne Braga Diamante Leiderman, William Gemio Jacobsen Teixeira, Douglas Kenji Narazaki, Alexandre Fogaça Cristante, Nelson Wolosker, Nelson de Luccia, Tarcísio Eloy Pessoa de Barros Filho
OBJECTIVE: To describe the endovascular treatment of late aortic erosive lesion by pedicle screw without screw removal. DESIGN: Case report. METHODS AND RESULTS: A breast cancer patient had a pathological fracture on T10, with spinal cord compression, and a pseudoaneurysm of the aorta in contact with an anterolateral pedicle screw. Endovascular surgery corrected the aortic lesion and allowed decompression, a week later, by posterior arthrodesis (T7-L1), with screw maintainance...
September 22, 2016: Annals of Vascular Surgery
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