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https://www.readbyqxmd.com/read/29451078/oncologists-perceptions-of-drug-affordability-using-nccn-evidence-blocks-results-from-a-national-survey
#1
Bijal Shah-Manek, William Wong, Arliene Ravelo, Marco DiBonaventura
BACKGROUND: The increasing prevalence of cancer coupled with approvals of new drugs and technologies used in therapy have brought increased scrutiny to the cost and value of treatments in oncology. To address the rising concern about oncology drug costs, several organizations have developed value frameworks to help assess the value of oncology regimens. The objective of this study was to assess oncologists' perceptions, awareness, and knowledge of all oncology value frameworks in the United States and to understand oncologists' perceptions of affordability in the context of National Comprehensive Cancer Network (NCCN) Evidence Blocks...
February 16, 2018: Journal of Managed Care & Specialty Pharmacy
https://www.readbyqxmd.com/read/29429750/arteriovenous-fistula-maturation-in-prevalent-hemodialysis-patients-in-the-united-states-a%C3%A2-national%C3%A2-study
#2
Kenneth J Woodside, Sarah Bell, Purna Mukhopadhyay, Kaitlyn J Repeck, Ian T Robinson, Ashley R Eckard, Sudipta Dasmunshi, Brett W Plattner, Jeffrey Pearson, Douglas E Schaubel, Ronald L Pisoni, Rajiv Saran
BACKGROUND: Arteriovenous fistulas (AVFs) are the preferred form of hemodialysis vascular access, but maturation failures occur frequently, often resulting in prolonged catheter use. We sought to characterize AVF maturation in a national sample of prevalent hemodialysis patients in the United States. STUDY DESIGN: Nonconcurrent observational cohort study. SETTING & PARTICIPANTS: Prevalent hemodialysis patients having had at least 1 new AVF placed during 2013, as identified using Medicare claims data in the US Renal Data System...
February 8, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29424185/predictors-of-early-failure-and-secondary-patency-in-native-arteriovenous-fistulas-for-hemodialysis
#3
Rui Abreu, Sara Rioja, Joaquin Vallespin, Xavier Vinuesa, Ruben Iglesias, Jose Ibeas
BACKGROUND: Native arteriovenous fistula (AVF) is considered the gold standard of vascular access for hemodialysis due to its longer survival, fewer complications, lower mortality and costs. Patency is important for effective dialysis treatment and this remains a challenge in nephrology. There are no well-defined prognostic factors for early and long-term AVF survival. The aim of this study was to evaluate comorbidity, analytical and ultrasound (US) variables as prognostic factors for early failure and AVF patency...
February 8, 2018: International Angiology: a Journal of the International Union of Angiology
https://www.readbyqxmd.com/read/29421426/surgical-treatment-of-cephalic-arch-problems-in-arteriovenous-fistulas-a-center-experience
#4
Mónica Fructuoso, Joana Ferreira, Pedro Sousa
INTRODUCTION: Cephalic arch problems, mainly stenosis (CAS), are a common cause of arteriovenous fistulas (AVFs) failure and the most effective treatment is yet to be clearly defined. Restenosis usually occurs soon and multiple interventions become necessary to maintain patency and functionality. The authors present the experience of their center with cephalic vein transposition in a group of patients with different problems involving the cephalic arch. MATERIAL AND METHODS: After consultation of the medical records, an observational retrospective analysis was performed to evaluate the outcomes of surgical treatment in cephalic arch problems of AVFs treated at the author's center between January of 2013 and December of 2015...
February 5, 2018: Annals of Vascular Surgery
https://www.readbyqxmd.com/read/29415296/vascular-anomalies-part-ii-interventional-therapy-of-peripheral-vascular-malformations
#5
René Müller-Wille, Moritz Wildgruber, Maliha Sadick, Walter A Wohlgemuth
BACKGROUND:  The International Society for the Study of Vascular Anomalies (ISSVA) categorizes vascular anomalies into vascular tumors and vascular malformations. Vascular malformations are further divided into slow-flow (venous, lymphatic, and capillary malformation) and fast-flow malformations (arteriovenous malformation and arteriovenous fistula). This interdisciplinary classification has therapeutic implications. METHODS:  The objective of this article is to provide concise information about the current terminology and treatment strategies of peripheral vascular malformations, based on the currently available literature, with a focus on interventional therapy of venous malformations (VM), lymphatic malformations (LM), arteriovenous malformations (AVM) and arteriovenous fistulae (AVF)...
February 7, 2018: RöFo: Fortschritte Auf Dem Gebiete der Röntgenstrahlen und der Nuklearmedizin
https://www.readbyqxmd.com/read/29405655/a-case-of-cardiac-sarcoidosis-mimicking-cardiac-amyloidosis-on-cardiovascular-magnetic-resonance
#6
Kazunori Takemura, Ryuta Nakamura, Kazuhito Shimazu, Youichiro Sugimoto, Tetsuro Takase, Minamimoto Ryogo, Michiaki Hiroe
A 52-year-old male visited our hospital with abnormal electrocardiogram and exertional fatigue. The electrocardiogram showed first-degree atrioventricular block, complete right bundle branch block, and inverted T waves in Leads II, III, aVF, V3, and V4. Echocardiography showed biventricular wall thickening involving granular sparkling of the interventricular septum. Late gadolinium enhancement on cardiovascular magnetic resonance (CMR) was found at the circumferential right ventricular wall and patchy regions of the left ventricle...
February 5, 2018: ESC Heart Failure
https://www.readbyqxmd.com/read/29402346/standard-electrocardiographic-data-from-capuchin-monkeys-cebus-apella-linnaeus-1758
#7
André B de Souza, Renan P S Rodrigues, Gerson T Pessoa, Andrezza Bs da Silva, Laecio S Moura, Francisco Ca Sousa, Elzivânia G da Silva, Anaemilia N Diniz, Maria Aps Barbosa, Jefferson R Araújo, Igor C Santos, Porfirio C Guerra, Jacyara Jrp Alves, Kássio V Macedo, Bruno Lm Diniz, Danielle C Marques, Flávio R Alves
Capuchin monkeys are a species of arboreal primate found in all South American countries. These monkeys have been highlighted for their potential for biomedical research due to their anatomic and physiologic similarities and genetic homology with humans. Here we characterized the electrocardiographic tracings from 12 healthy, young capuchin monkeys that were restrained with ketamine and midazolam. All 12 monkeys had normal sinus rhythms. Neither P-wave duration, PR interval, QT interval, nor P- or R-wave amplitude (in millivolts) differed between males and females...
January 1, 2018: Journal of the American Association for Laboratory Animal Science: JAALAS
https://www.readbyqxmd.com/read/29401294/the-first-365-days-on-haemodialysis-variation-in-the-haemodialysis-access-journey-and-its-associated-burden
#8
Eleanor Murray, Mahmoud Eid, Jamie P Traynor, Karen S Stevenson, Ram Kasthuri, David B Kingsmore, Peter C Thomson
Background: The modality by which haemodialysis (HD) is delivered [arteriovenous fistula (AVF), arteriovenous graft (AVG) or central venous catheter (CVC)] varies widely and is influenced by clinical evidence, patient factors and the prevailing service configuration. The aim of this study was to determine the outcome and impact of access strategy on patient outcome by mapping out the HD journey in a cohort of incident patients. Methods: A 2-year cohort of consecutive incident HD patients from the point of referral for first dialysis access to completion of the first 365 days of HD was prospectively reviewed...
February 1, 2018: Nephrology, Dialysis, Transplantation
https://www.readbyqxmd.com/read/29398197/clinical-presentation-and-treatment-paradigms-in-patients-with-hereditary-hemorrhagic-telangiectasia-and-spinal-vascular-malformations
#9
Ilyas Eli, Nicholas T Gamboa, Evan J Joyce, Min S Park, Philipp Taussky, Richard H Schmidt, William T Couldwell, Jamie McDonald, Kevin J Whitehead, M Yashar S Kalani
Hereditary hemorrhagic telangiectasia (HHT) is an autosomal dominant disorder that causes angiodysplasia and results in mucocutaneous telangiectasias and arteriovenous malformations of organs. Although central nervous system vascular malformations can occur anywhere along the neuraxis, spinal vascular malformations are rare. We present our experience with the presentation and management of spinal vascular malformations in patients with HHT. Of the more than 800 patients with the diagnosis of HHT screened at our institution from 1995 through 2017, four patients with spinal vascular malformations (age range 1 month-77 years; 2 male, 2 female) were identified, three of whom came to clinical attention after significant neurological deterioration from previously unknown malformations...
February 2, 2018: Journal of Clinical Neuroscience: Official Journal of the Neurosurgical Society of Australasia
https://www.readbyqxmd.com/read/29398178/relationships-between-clinical-processes-and-arteriovenous-fistula-cannulation-and-maturation-a%C3%A2-multicenter-prospective-cohort-study
#10
Michael Allon, Peter B Imrey, Alfred K Cheung, Milena Radeva, Charles E Alpers, Gerald J Beck, Laura M Dember, Alik Farber, Tom Greene, Jonathan Himmelfarb, Thomas S Huber, James S Kaufman, John W Kusek, Prabir Roy-Chaudhury, Michelle L Robbin, Miguel A Vazquez, Harold I Feldman
BACKGROUND: Half of surgically created arteriovenous fistulas (AVFs) require additional intervention to effectively support hemodialysis. Postoperative care and complications may affect clinical maturation. STUDY DESIGN: Hemodialysis Fistula Maturation (HFM) Study, a 7-center prospective cohort study. SETTING & PARTICIPANTS: 491 patients with single-stage AVFs who had neither thrombosis nor AVF intervention before a 6-week postoperative ultrasonographic examination and who required maintenance hemodialysis...
February 2, 2018: American Journal of Kidney Diseases: the Official Journal of the National Kidney Foundation
https://www.readbyqxmd.com/read/29391102/the-burden-of-tunneled-central-venous-catheters-for-hemodialysis-in-a-county-hospital
#11
Eric Pillado, Abraham Korn, Christian de Virgilio, Nina Bowens
Prolonged use of central venous catheters (CVCs) for hemodialysis (HD) is associated with greater morbidity and mortality when compared with autogenous arteriovenous fistulas (AVF). The objective was to assess compliance with CVC guidelines in adults referred for hemoaccess at a county teaching hospital. Out of 256 patients, 172 (67.2%) were male, with a mean age of 50.0 ± 12.4 years. Overall 62.5 per cent initiated dialysis via CVC. Patients were divided into two groups (those with CVC (62.5%) and those without (37...
October 1, 2017: American Surgeon
https://www.readbyqxmd.com/read/29390549/five-year-follow-up-results-of-posterior-decompression-and-fixation-surgery-for-delayed-neural-disorder-associated-with-osteoporotic-vertebral-fracture
#12
Taketoshi Yasuda, Yoshiharu Kawaguchi, Kayo Suzuki, Masato Nakano, Shoji Seki, Kenta Watabnabe, Masahiko Kanamori, Tomoatsu Kimura
Usually, after osteoporotic vertebral fracture (OVF), bone healing follows a normal clinical course leading to bone union with conservative treatment using a brace. However, some patients with OVF do not undergo the normal fracture healing process for a few months, possibly leading to delayed union and/or pseudoarthrosis. In these cases, we performed posterior surgery with combined decompression, vertebroplasty, and posterior spinal fusion with spinal instrumentation. This study aimed to determine the clinical results of posterior surgery for delayed neural disorder secondary to OVF over a 5-year follow-up...
December 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29382064/human-identification-by-cross-correlation-and-pattern-matching-of-personalized-heartbeat-influence-of-ecg-leads-and-reference-database-size
#13
Irena Jekova, Vessela Krasteva, Ramun Schmid
Human identification (ID) is a biometric task, comparing single input sample to many stored templates to identify an individual in a reference database. This paper aims to present the perspectives of personalized heartbeat pattern for reliable ECG-based identification. The investigations are using a database with 460 pairs of 12-lead resting electrocardiograms (ECG) with 10-s durations recorded at time-instants T1 and T2 > T1 + 1 year. Intra-subject long-term ECG stability and inter-subject variability of personalized PQRST (500 ms) and QRS (100 ms) patterns is quantified via cross-correlation, amplitude ratio and pattern matching between T1 and T2 using 7 features × 12-leads...
January 27, 2018: Sensors
https://www.readbyqxmd.com/read/29381986/st-segment-elevation-associated-with-hydrochloric-acid-ingestion-a-case-report
#14
I-Jeng Yeh, Kuan-Ting Liu
RATIONALE: Electrocardiography (ECG) was used to diagnose acute coronary syndrome, but many other diseases may also result in ST segment change. We report one case of ingested hydrochloric acid present with ST segment elevation in the ECG. However, subsequent coronary angiography did not reveal significant coronary occlusion. PATIENT CONCERNS: An 83-year-old female was transferred to our emergency department (ED) from the branch hospital due to ingestion of toilet bowl cleaner containing 9...
November 2017: Medicine (Baltimore)
https://www.readbyqxmd.com/read/29362656/clinical-efficacy-and-safety-of-transcatheter-embolization-for-vascular-complications-after-percutaneous-nephrolithotomy
#15
Necdet Poyraz, Mehmet Balasar, İbrahim Erdem Gökmen, Osman Koç, Mehmet Giray Sönmez, Arif Aydın, Yunus Emre Göger, Ahmet Öztürk
Introduction: Percutaneous nephrolithotomy (PNL) is the preferred procedure for safe and effective surgical treatment of kidney stones. Hemorrhage is the most serious complication of PNL, resulting from pseudoaneurysm (PA) or arteriovenous fistula (AVF), and can usually be controlled with conservative treatment. Aim: To evaluate endovascular treatments and outcomes of vascular complications observed after PNL. Material and methods: We retrospectively reviewed data on 19 patients who underwent renal embolization due to post-PNL renal artery bleeding between March 2005 and September 2016...
December 2017: Wideochirurgia i Inne Techniki Mało Inwazyjne, Videosurgery and Other Miniinvasive Techniques
https://www.readbyqxmd.com/read/29357085/high-flow-arteriovenous-fistula-and-heart-failure-could-the-indexation-of-blood-flow-rate-and-echocardiography-have-a-role-in-the-identification-of-patients-at-higher-risk
#16
Pasquale Zamboli, Sergio Lucà, Silvio Borrelli, Carlo Garofalo, Maria Elena Liberti, Mario Pacilio, Stefano Lucà, Giuseppe Palladino, Massimo Punzi
BACKGROUND: Although only high-flow arteriovenous fistulas (AVFs) are postulated to cause high-output cardiac failure (HOCF), there are currently no universally accepted criteria defining a high-flow fistula. METHODS: To verify if vascular access blood flow (Qa) ≥ 2000 ml/min provides an accurate definition of high-flow fistula, we selected 29 consecutive patients with Qa ≥ 2000 ml/min at color-duplex ultrasound examination and assessed them for the presence of cardiac failure symptoms; transthoracic echocardiography was also performed...
January 22, 2018: Journal of Nephrology
https://www.readbyqxmd.com/read/29356404/utility-of-perioperative-skin-perfusion-pressure-measurement-for-treatment-of-ulcers-caused-by-arteriovenous-access-ischaemic-steal
#17
Daisuke Atomura, Junko Aihara, Makoto Omori, Hiroto Terashi
Arteriovenous access ischaemic steal is a serious complication following arteriovenous fistula (AVF) construction. The aim of treatment is to improve distal circulation without impairing the function of the fistula. Therefore, any repair should be performed with intraoperative monitoring. We report 2 cases of this disorder treated using perioperative measurement of skin perfusion pressure (SPP) for preoperative surgical planning and intraoperative guidance. A 73-year-old woman with a left cubital AVF developed gangrene of the tip of the left little finger...
January 22, 2018: International Wound Journal
https://www.readbyqxmd.com/read/29354627/vascular-complications-related-to-posterior-lumbar-disc-surgery
#18
Hong Sung Jung, Dae Jung Kim, Hyo Shin Kim, Ho Kyun Lee, Soo Jin Na Choi, Sang Young Chung
Purpose: To evaluate patients who underwent surgical or endovascular treatment after vascular injury related to posterior lumbar disc surgery. Materials and Methods: We retrospectively reviewed seven cases of vascular injuries (four lacerations, one arteriovenous fistula [AVF], and two pseudoaneurysms) related to lumbar disc surgery by a posterior approach from January 1997 to December 2016 at Chonnam National University Hospital. Information of patient characteristics, diagnosis, treatment strategies, and outcomes were analyzed...
December 2017: Vascular Specialist International
https://www.readbyqxmd.com/read/29352055/concomitant-conus-medullaris-arteriovenous-shunts-and-sacral-dural-arteriovenous-fistulas-pathophysiological-links-related-to-the-venous-drainage-of-the-lesions-in-a-series-of-five-cases
#19
Andrea Rosi, Arturo Consoli, Stéphanie Condette-Auliac, Oguzhan Coskun, Federico Di Maria, Georges Rodesch
BACKGROUND: Spinal cord arteriovenous shunts (scAVSs) are a group of lesions located in the spinal cord itself or in the surrounding structures. The most common scAVSs are spinal dural arteriovenous fistulas (sDAVFs), which are acquired lesions. The pathogenesis of sDAVFs involves thrombosis and venous hypertension as trigger factors. Intradural scAVSs such as spinal cord arteriovenous nidus type malformations (AVMs) and pial arteriovenous fistulas are less common than sDAVFs and are considered to have a so-called 'congenital' origin...
January 19, 2018: Journal of Neurointerventional Surgery
https://www.readbyqxmd.com/read/29349919/analysis-of-follow-up-methods-of-vascular-access-and-patient-outcomes-in-hemodialysis-at-a-tertiary-care-hospital-in-china
#20
Ying Zhang, Xianglei Kong, Lijun Tang, Yong Wei, Dongmei Xu
Arteriovenous fistula is the preferred option for vascular access in hemodialysis patients. The aim of this study was to assess different follow-up methods for hemodialysis patients in our hemodialysis center in China. A cohort of 124 patients with stage 3 chronic kidney disease was recruited and double-blind randomly assigned into two groups. Patients in Group A received phone calls to schedule their next consultation a week in advance. Patients in Group B scheduled their next appointment at the end of each visit...
January 19, 2018: Therapeutic Apheresis and Dialysis
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