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Inhaler adherence

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https://www.readbyqxmd.com/read/28088742/patterns-of-drug-use-and-hiv-infection-among-adults-in-a-nationally-representative-sample
#1
Stephanie Shiau, Stephen M Arpadi, Michael T Yin, Silvia S Martins
BACKGROUND: Little is known about drug use patterns among people living with HIV in comparison to an uninfected group in the general population. The aim of this study was to investigate the association between legal and illegal drug use and HIV infection in a nationally representative sample of adults in the United States. METHODS: Public use data files (2005-2014) from the National Survey on Drug Use and Health (NSDUH) were used. Respondents were asked whether a medical professional had ever told them that they had HIV/AIDS...
January 7, 2017: Addictive Behaviors
https://www.readbyqxmd.com/read/28069068/the-sygma-programme-of-phase-3-trials-to-evaluate-the-efficacy-and-safety-of-budesonide-formoterol-given-as-needed-in-mild-asthma-study-protocols-for-two-randomised-controlled-trials
#2
Paul M O'Byrne, J Mark FitzGerald, Nanshan Zhong, Eric Bateman, Peter J Barnes, Christina Keen, Gun Almqvist, Kristine Pemberton, Carin Jorup, Stefan Ivanov, Helen K Reddel
BACKGROUND: In many patients with mild asthma, the low frequency of symptoms and the episodic nature of exacerbations make adherence to regular maintenance treatment difficult. This often leads to over-reliance on short-acting β2-agonist (SABA) reliever medication and under-treatment of the underlying inflammation, with poor control of asthma symptoms and increased risk of exacerbations. The use of budesonide/formoterol 'as needed' in response to symptoms may represent an alternative treatment option for patients with mild asthma...
January 10, 2017: Trials
https://www.readbyqxmd.com/read/28043593/new-approaches-in-drug-treatment-for-tuberculosis-inhalation-using-liposomes-only-a-future-vision-or-soon-in-clinical-practice
#3
Lars-Olof Larsson
A major change of therapy in respiratory medicine has been the transition from oral or parenteral to inhalation therapy, for example, in asthma. Inhalation of anti-infectious drugs has however not a key-role in the treatment of pulmonary infections such as tuberculosis (TB). The inhalation therapy provides several benefits; the target is reached directly with evasion of first-pass metabolism, thereby resulting in reduced systemic side effects. Furthermore, the drug is delivered to an extensive surface area that is rich in lymphoid tissue...
December 2016: International Journal of Mycobacteriology
https://www.readbyqxmd.com/read/27993284/non-persistence-and-non-adherence-to-long-acting-copd-medication-therapy-a-retrospective-cohort-study-based-on-a-large-german-claims-dataset
#4
Sabrina Mueller, Thomas Wilke, Benno Bechtel, Yogesh Suresh Punekar, Karen Mitzner, J Christian Virchow
OBJECTIVES: The main objectives of this study, based on a large cohort of German COPD patients, were to assess the level of non-persistence (NP) and non-adherence (NA) with long-acting COPD inhaler treatment and to describe factors that may be associated with NP and NA. METHODS: This was a retrospective cohort analysis based on claims data provided by a German statutory health insurance fund (years 2010-2012). NP was analyzed for treatment-naïve patients only; it was defined as a gap of >90 days in medication availability...
January 2017: Respiratory Medicine
https://www.readbyqxmd.com/read/27979018/patient-adherence-and-effective-communication
#5
Don A Bukstein
BACKGROUND: Poor adherence to inhaled corticosteroid medication is a critical problem for asthma because it contributes to morbidity and mortality through poor asthma control, frequent asthma exacerbations, acute care visits, and oral corticosteroid use. OBJECTIVE: To discuss evidence-based, time-efficient strategies that can be adopted by most practitioners to try to increase patient adherence. METHODS: Asthma management guidelines and other key publications are used to enhance discussion...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27979017/inhalation-devices-delivery-systems-and-patient-technique
#6
Harold S Nelson
BACKGROUND: In real-life clinical settings, physicians often consider the properties of various inhaled corticosteroids (ICSs), but typically little consideration is given to the properties of different inhalers and formulations. OBJECTIVE: To discuss the effects of inhalation devices and user technique on efficacy, safety, and adherence with the aim of improving asthma management. METHODS: Relevant publications were selected to augment discussion...
December 2016: Annals of Allergy, Asthma & Immunology
https://www.readbyqxmd.com/read/27942102/quality-of-acute-asthma-care-in-two-tertiary-hospitals-in-a-state-in-south-western-nigeria-a-report-of-clinical-audit
#7
Olufemi Olumuyiwa Desalu, Adekunle Olatayo Adeoti, Olarinde Jeffrey Ogunmola, Joseph Olusesan Fadare, Tolutope Fasanmi Kolawole
BACKGROUND: To audit the quality of acute asthma care in two tertiary hospitals in a state in the southwestern region of Nigeria and to compare the clinical practice against the recommendations of the Global Initiative for Asthma (GINA) guideline. PATIENTS AND METHODS: We carried out a retrospective analysis of 101 patients who presented with acute exacerbation of asthma to the hospital between November 2010 and October 2015. RESULTS: Majority of the cases were females (66...
November 2016: Nigerian Medical Journal: Journal of the Nigeria Medical Association
https://www.readbyqxmd.com/read/27941744/assessing-attitudes-and-perceptions-of-obstructive-pulmonary-disease-patients-towards-inhaler-therapy-in-a-low-income-country-a-cross-sectional-study
#8
M Z Farooq, W Waqar, M Mustaqeem, M S Farooq, J A Khan, M Hassan
Chronic respiratory diseases (CRD) like asthma and chronic obstructive pulmonary disease (COPD) are one of the leading causes of morbidity and mortality worldwide. A patient's perception, about his or her medicine, may have an impact on adherence to medications. The purpose was to assess the attitudes and perceptions, regarding inhaler therapy use, among patients with obstructive pulmonary disease in Pakistan, a developing country. With a questionnaire developing this cross-sectional study was conducted at the Department of Medicine's outpatient clinic at Civil Hospital, Karachi from October 2013 to January 2014...
October 2016: Mymensingh Medical Journal: MMJ
https://www.readbyqxmd.com/read/27914817/what-really-happens-in-the-home-the-medication-environment-of-urban-minority-youth
#9
Andrea A Pappalardo, Kelly Karavolos, Molly A Martin
BACKGROUND: Asthma disproportionately affects minority youth. Understanding the home medication environment and its relation to medication adherence can shape interventions to improve health outcomes. OBJECTIVE: The objective of this study was to describe the asthma medication environment in the homes of urban minority youth and to determine predictors of medication use and technique in this population. METHODS: Baseline data from 2 cohorts of minority youth with asthma in Chicago were combined for cross-sectional analysis...
November 30, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27890987/a-search-for-covert-precipitating-clinical-parameters-in-frequent-exacerbators-of-chronic-obstructive-pulmonary-disease
#10
Ankit Bhatia, Ved Prakash, Surya Kant, Ajay Kumar Verma
INTRODUCTION: Acute exacerbations are a significant source of morbidity and mortality associated with chronic obstructive pulmonary disease (COPD). Some patients suffer an inordinate number of exacerbations while others remain relatively protected. The aim of this study was to evaluate the potentially modifiable precipitating parameters of frequent severe exacerbations requiring hospital admission in COPD. MATERIALS AND METHODS: Consecutive patients admitted with acute exacerbation of COPD for a period of one year in a tertiary care hospital were evaluated prospectively...
November 2016: Lung India: Official Organ of Indian Chest Society
https://www.readbyqxmd.com/read/27888027/can-exhaled-nitric-oxide-fraction-predict-adherence-to-inhaled-corticosteroids-in-atopic-and-nonatopic-children-with-asthma
#11
Ted Klok, Paul L P Brand
No abstract text is available yet for this article.
November 22, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27880049/understanding-clinicians-attitudes-toward-a-mobile-health-strategy-to-childhood-asthma-management-a-qualitative-study
#12
Jessica P Hollenbach, Anna Cushing, Emilie Melvin, Bryanna McGowan, Michelle M Cloutier, Melissa Manice
OBJECTIVES: Mobile technology for childhood asthma can provide real-time data to enhance care. What real-time adherence information clinicians want, how they may use it, and if the data meet their clinical needs has not been fully explored. Our goal was to determine whether pediatric primary care and pulmonary clinicians believe a sensor-based mobile intervention is useful in caring for patients with asthma. METHODS: We recruited participants from 3 urban, primary care and 1 pulmonary practice from July to September 2015 in Hartford, CT...
November 23, 2016: Journal of Asthma: Official Journal of the Association for the Care of Asthma
https://www.readbyqxmd.com/read/27875376/rhinitis-adherence-to-treatment-and-new-technologies
#13
Fulvio Braido, Ilaria Baiardini, Francesca Puggioni, Silvia Garuti, Ruby Pawankar, G Walter Canonica
PURPOSE OF REVIEW: Nonadherence to treatment is a major issue in approximately 50% of patients suffering from chronic diseases. The availability of new technologies could represent a possible way to improve patients' engagement and adherence in a real-life setting. Research and technology tools made available or in process of being made available to patients with allergic diseases and their physicians could potentially improve the management of these disease in daily life by improving adherence...
February 2017: Current Opinion in Allergy and Clinical Immunology
https://www.readbyqxmd.com/read/27853357/feasibility-of-a-novel-mhealth-management-system-to-capture-and-improve-medication-adherence-among-adolescents-with-asthma
#14
Anna Cushing, Melissa P Manice, Andrew Ting, Michael K Parides
PURPOSE: Currently, 7.1 million children in the United States have asthma. Nonadherence to daily controller asthma medication is common, leading to more severe symptoms, overuse of rescue medication, and increased hospitalizations. The purpose of this study was to develop and evaluate the feasibility and acceptability of a novel mHealth management system composed of a sensored device, which is connected to mobile phone app that is designed to monitor and improve asthma medication adherence...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27843303/communication-during-counseling-sessions-about-inhaled-corticosteroids-at-the-community-pharmacy
#15
Jeanine A Driesenaar, Peter Agm De Smet, Rolf van Hulten, Litje Hu, Sandra van Dulmen
BACKGROUND: Pharmaceutical care is one of the major tasks of pharmacists, which aims to improve patient outcomes. Counseling patients with asthma or chronic obstructive pulmonary disease about their use of inhaled corticosteroids (ICS) might enhance medication adherence and symptom control. Therefore, effective pharmacist-patient communication is very important. In this regard, both affective communication, for handling emotions, and instrumental communication, for exchanging biomedical and lifestyle information, are relevant...
2016: Patient Preference and Adherence
https://www.readbyqxmd.com/read/27823608/insulin-making-sense-of-current-options
#16
REVIEW
Alissa R Segal, Tejaswi Vootla, Richard S Beaser
Newer insulin products have advanced the evolution of insulin replacement options to more accurately mimic natural insulin action. There are new, modified, and concentrated insulins; administration devices calibrated for both increased concentrations and administration accuracy to improve adherence and safety; and inhaled insulin. There are new combinations of longer-acting basal insulin and rapid-acting insulin or glucagon like protein-1 receptor agonists. Existing insulin replacement designs and methods can be updated using these tools to improve efficacy and safety...
December 2016: Endocrinology and Metabolism Clinics of North America
https://www.readbyqxmd.com/read/27815524/staar-a-randomised-controlled-trial-of-electronic-adherence-monitoring-with-reminder-alarms-and-feedback-to-improve-clinical-outcomes-for-children-with-asthma
#17
Robert W Morton, Heather E Elphick, Alan S Rigby, William J Daw, David A King, Laurie J Smith, Mark L Everard
BACKGROUND: Suboptimal adherence to inhaled steroids is common in children with asthma and is associated with poor disease control, reduced quality of life and even death. Previous studies using feedback of electronically monitored adherence data have demonstrated improved adherence, but have not demonstrated a significant impact on clinical outcomes. The aim of this study was to determine whether introduction of this approach into routine practice would result in improved clinical outcomes...
November 4, 2016: Thorax
https://www.readbyqxmd.com/read/27815064/inhaled-corticosteroid-adherence-patterns-in-a-longitudinal-asthma-cohort
#18
Patrick C Souverein, Ellen S Koster, Gene Colice, Eric van Ganse, Alison Chisholm, David Price, Alexandra L Dima
BACKGROUND: Electronic prescribing records can enable exploration of medication adherence, but analysis decisions may influence estimates and require alignment to new consensus-based definitions. OBJECTIVE: To compare different computations of inhaled corticosteroid (ICS) implementation in a primary care asthma population initiating ICS therapy when assessed within episodes of persistent use, and examine longitudinal variation in implementation. METHODS: A historical cohort study was conducted on UK's Optimum Patient Care Research Database...
November 1, 2016: Journal of Allergy and Clinical Immunology in Practice
https://www.readbyqxmd.com/read/27809675/bentonite-toxicology-and-epidemiology-a-review
#19
L Daniel Maxim, Ron Niebo, Ernest E McConnell
Bentonite, a clay with numerous industrial and consumer applications, is mined and processed in many countries of the world. Its many beneficial uses also create the potential for widespread occupational and consumer exposure. The available studies on toxicity and epidemiology indicate that the principal exposure pathway of concern is inhalation of respirable dust by occupationally exposed cohorts. Bentonite itself is probably not more toxic than any other particulate not otherwise regulated and is not classified as a carcinogen by any regulatory or advisory body, but some bentonite may contain variable amounts of respirable crystalline silica, a recognized human carcinogen...
November 2016: Inhalation Toxicology
https://www.readbyqxmd.com/read/27796843/energy-efficient-monitoring-of-metered-dose-inhaler-usage
#20
Aris S Lalos, John Lakoumentas, Anastasios Dimas, Konstantinos Moustakas
Life-long chronic inflammatory diseases of the airways, such as asthma and Chronic Obstructive Pulmonary Disease, are very common worldwide, affecting people of all ages, race and gender. One of the most important aspects for the effective management of asthma is medication adherence which is defined as the extent to which patients follow their prescribed action plan and use their inhaler correctly. Wireless telemonitoring of the medication adherence can facilitate early diagnosis and management of these diseases through the use of an accurate and energy efficient mHealth system...
December 2016: Journal of Medical Systems
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