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https://www.readbyqxmd.com/read/28935185/impact-of-hospital-case-volume-on-testicular-cancer-outcomes-and-practice-patterns
#1
Solomon L Woldu, Justin T Matulay, Timothy N Clinton, Nirmish Singla, Laura-Maria Krabbe, Ryan C Hutchinson, Arthur Sagalowsky, Yair Lotan, Vitaly Margulis, Aditya Bagrodia
BACKGROUND: Given the rarity of testicular germ cell tumors (TGCTs) and the complex aspects of management, we evaluate the effect of hospital TGCT case volume on overall survival outcomes and practice patterns. MATERIALS AND METHODS: The National Cancer Database was queried for patients diagnosed with seminoma or nonseminomatous germ cell tumor (NSGCT). Hospitals were classified by case volume as high (99th percentile, ≥26.1 cases annually), high-intermediate (95-99th percentile, 14...
September 18, 2017: Urologic Oncology
https://www.readbyqxmd.com/read/28934537/effect-of-retroperitoneal-pelvic-packing-on-pelvic-cavity-pressure-a-cadaveric-study
#2
Yukio Sato, Kazuhiko Sekine, Takayuki Shibusawa, Kosuke Tajima, Junichi Sasaki, Nobuaki Imanishi, Sadakazu Aiso, Shingo Hori
Limited clinical evidence demonstrates the effectiveness of direct retroperitoneal pelvic packing for hemorrhage control in pelvic fractures due to the difficulty in measuring pressure on the pelvic walls within the pelvic cavity after retroperitoneal pelvic packing. Using a cadaver model, the authors aimed to assess whether retroperitoneal pelvic packing generates pressure that exceeds the venous return and arterial pressure in the pelvis. The pressure on the pelvic wall was measured in 5 fresh Japanese cadavers...
September 21, 2017: Orthopedics
https://www.readbyqxmd.com/read/28932734/spontaneous-ruptured-pheochromocytoma-an-unusual-case-report-and-literature-review
#3
Ye Seob Jee
Ruptured pheochromocytoma is a rare disease. Its mortality rate is up to 31%-50%. Proper management of ruptured pheochromocytoma remains unclear. A 44-year-old male patient visited our Emergency Department and presented with abrupt onset of left flank pain. His blood pressure was 190/140 mmHg with purse rate of 130 beats/min. CT scan showed 8.1 × 5.6-cm-sized heterogeneously mass with rupture on the left retroperitoneal space and active bleeding. His symptom of abdominal pain was aggravated. Follow-up laboratory analysis revealed elevated WBC count and decreased hemoglobin 2 hours after admission...
September 2017: Annals of Surgical Treatment and Research
https://www.readbyqxmd.com/read/28931294/-carney-triad
#4
L Fiala, I Kocáková, R Šimůnek, E Krejčí, I Babánková, R Šefr
Carney triad is a synchronous or metachronous association of gastric gastrointestinal stromal tumors (GIST), pulmonary chondroma and extra-adrenal paraganglioma. The majority of patients have only one or two components of the triad, all three tumors being found in only about 2% of the patients at the time of the first diagnosis. The most common combination is gastric and pulmonary tumors. We report a case of Carney triad which was diagnosed at Masaryk Memorial Cancer Institute. A 57-year-old female patient with a history of gastric resection for leiomyosarcoma at the age of 14 and with an unclear pulmonary lesion evident on chest X-ray since as early as 2003...
2017: Rozhledy V Chirurgii: Měsíčník Československé Chirurgické Společnosti
https://www.readbyqxmd.com/read/28930047/comparison-of-retroperitoneal-liposarcoma-extending-into-the-inguinal-canal-and-inguinoscrotal-liposarcoma
#5
Jinsoo Rhu, Chan Woo Cho, Kyo Won Lee, Hyojun Park, Jae Berm Park, Yoon-La Choi, Sung Joo Kim
BACKGROUND: This study was designed to analyze differences between retroperitoneal liposarcoma (RLPS) extending into the inguinal canal and inguinoscrotal liposarcoma. METHODS: We retrospectively reviewed the records for patients who were managed for inguinal liposarcoma at Samsung Medical Center, a tertiary hospital, between January 1998 and December 2016. Patient data on demographics, tumour location, surgery, adjuvant therapy, histology, recurrence and death were collected...
October 1, 2017: Canadian Journal of Surgery. Journal Canadien de Chirurgie
https://www.readbyqxmd.com/read/28928826/delineation-of-retroperitoneal-metastatic-lymph-nodes-in-ovarian-cancer-with-near-infrared-fluorescence-imaging
#6
Tao Pu, Liqin Xiong, Qiyu Liu, Minxing Zhang, Qingqing Cai, Haiou Liu, Anil K Sood, Guiling Li, Yu Kang, Congjian Xu
Lymph node metastasis occurs in early-stage and late-stage ovarian cancers. Systematic lymphadenectomy is frequently conducted in an attempt to prevent disease progression. However, this method is associated with multiple complications. Therefore, it is necessary to develop a less invasive and more sensitive method for detecting lymphatic metastasis in ovarian cancer. The aim of the present study was to develop an appropriate fluorescent label for the analysis of lymphatic metastasis in vivo. To this end, epithelial ovarian cancer cells with high potential for lymph node metastasis were labeled using mCherry fluorescence...
September 2017: Oncology Letters
https://www.readbyqxmd.com/read/28928422/role-of-chemotherapy-in-dedifferentiated-liposarcoma-of-the-retroperitoneum-defining-the-benefit-and-challenges-of-the-standard
#7
J A Livingston, D Bugano, A Barbo, H Lin, J E Madewell, W L Wang, A J Lazar, W W Tseng, C L Roland, B W Feig, R Pollock, A P Conley, R S Benjamin, S Patel, N Somaiah
Benefit from chemotherapy for well-differentiated/de-differentiated (WD/DD) liposarcomas has been reported to be minimal, however traditional response criteria may not adequately capture positive treatment effect. In this study, we evaluate benefit from first-line chemotherapy and characterize imaging response characteristics in patients with retroperitoneal (RP) WD/DD liposarcoma treated at The University of Texas MD Anderson Cancer Center. Response was assessed using RECIST (Response Evaluation Criteria in Solid Tumors) and an exploratory analysis of vascular response was characterized...
September 19, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28924109/retroperitoneal-bulky-histiocytic-sarcoma-successfully-treated-with-induction-chemotherapy-followed-by-curative-surgery
#8
Masafumi Oto, Akiko Maeda, Taku Nose, Yujiro Ueda, Shima Uneda, Akito Inadome, Koichi Oshima, Minoru Yoshida
Histiocytic sarcoma (HS) is a rare hematopoietic neoplasm. We report a patient with HS treated with induction chemotherapy followed by curative surgery. A 50-year-old man was referred to our hospital because of a retroperitoneal tumor. A computed tomography scan revealed a bulky retroperitoneal mass, infiltrating the surrounding organ. An excisional biopsy confirmed the diagnosis of HS. The tumor shrunk after multidrug chemotherapy. However, positron emission tomography showed uptake of fludeoxyglucose in the residual tumor...
September 15, 2017: Internal Medicine
https://www.readbyqxmd.com/read/28922263/prospective-side-by-side-comparison-of-outcomes-and-complications-with-a-simple-versus-intensive-anticoagulation-monitoring-strategy-in-pediatric-extracorporeal-life-support-patients
#9
Jane S Yu, Ryan P Barbaro, Donald A Granoski, Mary E Bauman, M Patricia Massicotte, Laurance L Lequier, Gail M Annich, Lindsay M Ryerson
OBJECTIVES: A continuous infusion of unfractionated heparin is the most common anticoagulant used for pediatric patients on extracorporeal life support. The objective of this study was to compare extracorporeal life support complications and outcomes between two large-volume pediatric extracorporeal life support centers that use different anticoagulation strategies. DESIGN: Prospective, observational cohort study. SETTING: The University of Michigan used simple anticoagulation monitoring, whereas the University of Alberta used an intensive anticoagulation monitoring strategy...
September 15, 2017: Pediatric Critical Care Medicine
https://www.readbyqxmd.com/read/28920771/what-you-don%C3%A2-t-see-can-kill-you
#10
Richard J Fantus
Traumatic retroperitoneal hematoma is a potentially life-threatening condition associated with both blunt and penetrating injury mechanisms to the structures in that region.
March 2017: Bulletin of the American College of Surgeons
https://www.readbyqxmd.com/read/28918405/renal-cell-carcinoma-with-isolated-metastasis-to-sigmoid-mesentery-a-rare-resectable-combination
#11
Hira Lal, Priyank Yadav, Shashidhar Achar, Uday Pratap Singh
Renal cell carcinoma accounts for 2%-3% of all malignancies in adults. It spreads via direct extension, lymphatic route as well as haematogenous route. Lymph nodes, lungs, bone, liver and brain are the usual sites for its metastatic spread. In the presence of limited metastatic disease with potentially resectable metastases, surgery offers the best chances of cure. In the present case, we describe a case of renal cell carcinoma with a solitary metastasis to the sigmoid mesentery in a patient with Von Hippel-Lindau syndrome...
September 15, 2017: BMJ Case Reports
https://www.readbyqxmd.com/read/28918295/case-report-primary-aortosigmoid-fistula-a-rare-cause-of-lower-gastrointestinal-bleeding
#12
Chirin Khalaf, Kim C Houlind
INTRODUCTION: A primary aortoenteric fistula (PAEF) is a communication between aorta and the gastrointestinal tract. It is a rare condition that is difficult to diagnose and therefore associated with a high mortality. PRESENTATION OF CASE: We report a rare case of a 66-year old man with an unstable bleeding PAEF. A salvage procedure was performed with a covered stent. Later, a sigmoidectomy was performed with resection of the fistula. Postoperatively, the patient suffered an infection that was treated well with antibiotics and he was discharged two weeks later with complete resolution of the fistula...
September 2, 2017: International Journal of Surgery Case Reports
https://www.readbyqxmd.com/read/28917595/perioperative-and-oncologic-outcomes-of-nephrectomy-and-caval-thrombectomy-using-extracorporeal-circulation-and-deep-hypothermic-circulatory-arrest-for-renal-cell-carcinoma-invading-the-supradiaphragmatic-inferior-vena-cava-and-or-right-atrium
#13
Alessandro Nini, Umberto Capitanio, Alessandro Larcher, Paolo Dell'Oglio, Federico Dehò, Nazareno Suardi, Fabio Muttin, Cristina Carenzi, Massimo Freschi, Roberta Lucianò, Giovanni La Croce, Alberto Briganti, Renzo Colombo, Andrea Salonia, Alessandro Castiglioni, Patrizio Rigatti, Francesco Montorsi, Roberto Bertini
BACKGROUND: Radical nephrectomy (RN) and caval thrombectomy (CT) for renal cell carcinoma, with extracorporeal circulation (ECC) and deep hypothermic circulatory arrest (DHCA) is a challenging surgical approach. OBJECTIVE: To assess peri-operative and oncologic outcomes of renal cell carcinoma patients treated with RN and CT, using ECC and DHCA. DESIGN, SETTING, AND PARTICIPANTS: We retrospectively evaluated 46 patients who underwent RN and CT using ECC and DHCA...
September 13, 2017: European Urology
https://www.readbyqxmd.com/read/28916965/factors-affecting-operative-efficiency-and-post-operative-convalescence-in-laparoendoscopic-single-site-less-adrenalectomy
#14
Yao-Chou Tsai, Chung-Hsien Chen, Ya-Hui Hu, Leay-Kiaw Er, Che-Hsiung Wu, Shih-Chieh Chueh, Victor Chia-Hsiang Lin
BACKGROUND: Laparoendoscopic single-site (LESS) adrenalectomy is a novel challenging technique which is still under clinical evaluation. Initial reports have revealed its superiority in patient convalescence. In addition, it has been reported that some patient or anatomic factors might affect the ergonomics of LESS adrenalectomy. The aim of this study is to investigate the possible factors that might affect procedural efficiency and patient convalescence in LESS adrenalectomy. METHODS: Between October 2009 and July 2015, 105 consecutive adult patients with benign adrenal tumors, who underwent LESS retroperitoneal adrenalectomy were enrolled in this study...
September 15, 2017: Surgical Endoscopy
https://www.readbyqxmd.com/read/28916408/robot-assisted-kidney-transplantation-the-european-experience
#15
Alberto Breda, Angelo Territo, Luis Gausa, Volkan Tuğcu, Antonio Alcaraz, Mireia Musquera, Karel Decaestecker, Liesbeth Desender, Michael Stockle, Martin Janssen, Paolo Fornara, Nasreldin Mohammed, Giampaolo Siena, Sergio Serni, Luis Guirado, Carma Facundo, Nicolas Doumerc
BACKGROUND: Robot-assisted kidney transplantation (RAKT) has recently been introduced to reduce the morbidity of open kidney transplantation (KT). OBJECTIVE: To evaluate perioperative and early postoperative RAKT outcomes. DESIGN, SETTING AND PARTICIPANTS: This was a multicenter prospective observational study of 120 patients who underwent RAKT, predominantly with a living donor kidney, in eight European institutions between July 2015 and May 2017, with minimum follow-up of 1 mo...
September 12, 2017: European Urology
https://www.readbyqxmd.com/read/28913560/deregulation-of-obesity-relevant-genes-is-associated-with-progression-in-bmi-and-the-amount-of-adipose-tissue-in-pigs
#16
Caroline M Junker Mentzel, Tainã Figueiredo Cardoso, Christian Bressen Pipper, Mette Juul Jacobsen, Claus Bøttcher Jørgensen, Susanna Cirera, Merete Fredholm
The aim of this study was to elucidate the relative impact of three phenotypes often used to characterize obesity on perturbation of molecular pathways involved in obesity. The three obesity-related phenotypes are (1) body mass index (BMI), (2) amount of subcutaneous adipose tissue (SATa), and (3) amount of retroperitoneal adipose tissue (RPATa). Although it is generally accepted that increasing amount of RPATa is 'unhealthy', a direct comparison of the relative impact of the three obesity-related phenotypes on gene expression has, to our knowledge, not been performed previously...
September 14, 2017: Molecular Genetics and Genomics: MGG
https://www.readbyqxmd.com/read/28911640/long-term-feeding-of-red-algae-gelidium-amansii-ameliorates-glucose-and-lipid-metabolism-in-a-high-fructose-diet-impaired-glucose-tolerance-rat-model
#17
Hshuan-Chen Liu, Chun-Ju Chang, Tsung-Han Yang, Meng-Tsan Chiang
This study was designed to investigate the effect of Gelidium amansii (GA) on carbohydrate and lipid metabolism in rats with high fructose (HF) diet (57.1% w/w). Five-week-old male Sprague-Dawley rats were fed a HF diet to induce glucose intolerance and hyperlipidemia. The experiment was divided into three groups: (1) control diet group (Con); (2) HF diet group (HF); and (3) HF with GA diet group (HF + 5% GA). The rats were fed the experimental diets and drinking water ad libitum for 23 weeks. The results showed that GA significantly decreased retroperitoneal fat mass weight of HF diet-fed rats...
July 2017: Journal of Food and Drug Analysis
https://www.readbyqxmd.com/read/28905080/-treatment-of-retroperitoneal-sarcoma-in-germany-results-of-a%C3%A2-survey-of-the-german-society-of-general-and-visceral-surgery-the-german-interdisciplinary-sarcoma-study-group-and-the-advocacy-group-das-lebenshaus
#18
J Jakob, A Gerres, U Ronellenfitsch, L Pilz, M Wartenberg, B Kasper, H-R Raab, P Hohenberger
OBJECTIVE: Retroperitoneal sarcomas (RPSs) are rare cancers with some variability in clinical and histopathological presentation. In Germany, general treatment strategies of retroperitoneal sarcoma are unknown since centralized registries do not exist. The objective of this survey was to access the medical care of RPS patients in Germany. METHODS: In cooperation with the German Society of General and Visceral surgery, the German Interdisciplinary Sarcoma Study Group and the patient advocacy group Das Lebenshaus we designed an online survey assessing diagnostic and treatment strategies (e...
September 13, 2017: Der Chirurg; Zeitschrift Für Alle Gebiete der Operativen Medizen
https://www.readbyqxmd.com/read/28904243/solitary-fibrous-tumour-a-rare-cause-of-acute-abdomen
#19
Nicole Grech, Ernest Ellul, Neville Spiteri, Miljan Milic
Solitary Fibrous Tumours(SFT), previously known as haemangiopericytoma, are rarely encountered in surgery. They arise from mesenchyme tissue and can occur at several sites in the body - head and neck, extremities, thorax, abdomen and retroperitoneal space. In the thorax, where they arise from the pleura, and abdomen they may attain a large size before giving rise to symptoms. Most SFT behave in a benign manner. However a number of them recur locally or metastasize. Recurrences can occur several years after excision of the primary tumour...
March 29, 2017: Annali Italiani di Chirurgia
https://www.readbyqxmd.com/read/28903527/efficacy-of-early-ureteral-ligation-on-prevention-of-intravesical-recurrence-after-radical-nephroureterectomy-for-upper-urinary-tract-urothelial-carcinoma-a-prospective-single-arm-multicenter-clinical-trial
#20
Shinichi Yamashita, Akihiro Ito, Koji Mitsuzuka, Naomasa Ioritani, Shigeto Ishidoya, Yoshihiro Ikeda, Kenji Numahata, Kazuhiko Orikasa, Tatsuo Tochigi, Fumihiko Soma, Takashige Namima, Yoichi Arai
Objective: The rate of intravesical recurrence after radical nephroureterectomy for upper urinary tract urothelial carcinoma is high. Seeding upper urinary tract urothelial carcinoma cells onto the damaged bladder wall is considered to be one of the causes of intravesical recurrence after radical nephroureterectomy. We evaluated the utility of early ureteral ligation in preventing the intravesical recurrence. Methods: This prospective single-arm clinical trial included patients who underwent radical nephroureterectomy for upper urinary tract urothelial carcinoma in the Tohoku Urological Evidence-Based Medicine Study Group between 2012 and 2013...
September 1, 2017: Japanese Journal of Clinical Oncology
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