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https://www.readbyqxmd.com/read/28749566/the-facilitators-and-barriers-of-physical-activity-among-aboriginal-and-torres-strait-islander-regional-sport-participants
#1
Claudie Péloquin, Thomas Doering, Stephanie Alley, Amanda Rebar
BACKGROUND: Disparities in health perspectives between Indigenous and non-Indigenous populations are major concerns in many of the world's well-developed nations. Indigenous populations are largely less healthy, more prone to chronic diseases, and have an earlier overall mortality than non-Indigenous populations. Low levels of physical activity (PA) contribute to the high levels of disease in Indigenous Australians. METHOD: Qualitative analysis of structured one-on-one interviews discussing PA in a regional setting...
July 27, 2017: Australian and New Zealand Journal of Public Health
https://www.readbyqxmd.com/read/28749474/racial-ethnic-differences-in-multiple-gene-sequencing-results-for-hereditary-cancer-risk
#2
Jennifer L Caswell-Jin, Tanya Gupta, Evan Hall, Iva M Petrovchich, Meredith A Mills, Kerry E Kingham, Rachel Koff, Nicolette M Chun, Peter Levonian, Alexandra P Lebensohn, James M Ford, Allison W Kurian
PurposeWe examined racial/ethnic differences in the usage and results of germ-line multiple-gene sequencing (MGS) panels to evaluate hereditary cancer risk.MethodsWe collected genetic testing results and clinical information from 1,483 patients who underwent MGS at Stanford University between 1 January 2013 and 31 December 2015.ResultsAsians and Hispanics presented for MGS at younger ages than whites (48 and 47 vs. 55; P = 5E-16 and 5E-14). Across all panels, the rate of pathogenic variants (15%) did not differ significantly between racial groups...
July 27, 2017: Genetics in Medicine: Official Journal of the American College of Medical Genetics
https://www.readbyqxmd.com/read/28749436/disparities-in-snacking-trends-in-us-adults-over-a-35-year-period-from-1977-to-2012
#3
Elizabeth K Dunford, Barry M Popkin
BACKGROUND: Previous studies have indicated that snacking is contributing to increased calories in the American diet, and that the contribution of snacks to energy intake has increased in recent decades. OBJECTIVE: The objective was to examine trends in the energy intake deriving from snacks and food sources of snacks for US adults over 35 years from 1977 to 2012, and whether these trends differ across sociodemographic groups. METHODS: Participants included 74,291 US adults aged ≥19 years who participated in the 1977-1978 Nationwide Food Consumption Survey (NFCS); the 1989-1991 Continuing Survey of Food Intake by Individuals (CSFII), the 1994-1996 CSFII, the 1997-1998 CSFII, National Health and Nutrition Examination Survey (NHANES) 2003-2004, NHANES 2005-2006, NHANES 2009-2010 and NHANES 2011-2012; all surveys are a stratified random sample of the total civilian, non-institutionalized US population...
July 27, 2017: Nutrients
https://www.readbyqxmd.com/read/28749369/race-ethnicity-socioeconomic-status-residential-segregation-and-spatial-variation-in-noise-exposure-in-the-contiguous-united-states
#4
Joan A Casey, Rachel Morello-Frosch, Daniel J Mennitt, Kurt Fristrup, Elizabeth L Ogburn, Peter James
BACKGROUND: Prior research has reported disparities in environmental exposures in the United States, but, to our knowledge, no nationwide studies have assessed inequality in noise pollution. OBJECTIVES: We aimed to a) assess racial/ethnic and socioeconomic inequalities in noise pollution in the contiguous United States; and b) consider the modifying role of metropolitan level racial residential segregation. METHODS: We used a geospatial sound model to estimate census block group-level median () nighttime and daytime noise exposure and 90th percentile () daytime noise exposure...
July 25, 2017: Environmental Health Perspectives
https://www.readbyqxmd.com/read/28748728/experiences-and-attitudes-among-psychiatric-mental-health-advanced-practice-nurses-in-the-use-of-telemental-health-results-of-an-online-survey
#5
Martha B Baird, Lucinda Whitney, Cassie E Caedo
BACKGROUND: Telemental health (TMH) growth is driven by recent trends in health delivery systems and disparities in access to mental health services. There are currently no standard educational guidelines to prepare psychiatric mental health advanced practice nurses (PMH-APRNs) in TMH delivery. OBJECTIVE: To survey practicing PMH-APRNs across the United States about their experiences and attitudes about use of TMH. DESIGN: Eighty-three participants from the American Psychiatric Nurses Association online discussion board completed a nine-item survey...
July 1, 2017: Journal of the American Psychiatric Nurses Association
https://www.readbyqxmd.com/read/28748341/obstetric-and-perinatal-outcomes-among-immigrant-and-non-immigrant-women-in-berlin-germany
#6
Matthias David, Theda Borde, Silke Brenne, Babett Ramsauer, Wolfgang Henrich, Jürgen Breckenkamp, Oliver Razum
BACKGROUND: In Germany, regular immigrants and their descendants have legal and financial access to health care equal to the general citizenry. Nonetheless, some of their health outcomes are comparatively unfavorable, and that is only partially explained by their lower socioeconomic status (SES). The aim of this study was to assess whether this disparity exists also for obstetric and perinatal outcomes. METHODS: We compared obstetric and perinatal outcomes between immigrant women (first or second generation) and non-immigrant women, delivering at three maternity hospitals in Berlin, Germany, 2011-2012...
July 26, 2017: Archives of Gynecology and Obstetrics
https://www.readbyqxmd.com/read/28748331/eligibility-for-phase-3-clinical-trials-of-systemic-therapy-in-real-world-patients-with-metastatic-renal-cell-cancer-managed-in-a-rural-region
#7
Carsten Nieder, Mohsan A Syed, Astrid Dalhaug, Adam Pawinski, Jan Norum
Previous research has identified disparities between urban and rural cancer care, including clinical trial access. Therefore, we addressed three different questions in patients with metastatic renal cell cancer managed according to national guidelines in a rural Norwegian standard practice setting. (1) How many patients would have been eligible for three recent landmark randomized clinical trials? (2) Is survival different between eligible and non-eligible patients receiving first-line systemic therapy? (3) Is survival different between eligible patients and published trial results? We performed a retrospective analysis of 101 consecutive patients (2006-2016)...
September 2017: Medical Oncology
https://www.readbyqxmd.com/read/28748293/racial-disparities-in-outcomes-of-operatively-treated-lower-extremity-fractures
#8
Adam Driesman, Nina Fisher, Sanjit R Konda, Christian A Pean, Philipp Leucht, Kenneth A Egol
PURPOSE: Whether racial differences are associated with function in the long term following surgical repair of lower extremity fractures has not been investigated. The purpose of this study is to compare how race affects function at 3, 6 and 12 months post-surgery following certain lower extremity fractures. METHODS: Four hundred and eighteen patients treated operatively for a lower extremity fracture (199 tibial plateau, 39 tibial shaft, and 180 rotational ankle fractures) were prospectively followed for 1 year...
July 26, 2017: Archives of Orthopaedic and Trauma Surgery
https://www.readbyqxmd.com/read/28748112/visually-lossless-jpeg-2000-for-remote-image-browsing
#9
Han Oh, Ali Bilgin, Michael Marcellin
Image sizes have increased exponentially in recent years. The resulting high-resolution images are often viewed via remote image browsing. Zooming and panning are desirable features in this context, which result in disparate spatial regions of an image being displayed at a variety of (spatial) resolutions. When an image is displayed at a reduced resolution, the quantization step sizes needed for visually lossless quality generally increase. This paper investigates the quantization step sizes needed for visually lossless display as a function of resolution, and proposes a method that effectively incorporates the resulting (multiple) quantization step sizes into a single JPEG2000 codestream...
September 2016: Information (Basel)
https://www.readbyqxmd.com/read/28747658/a-single-amino-acid-substitution-confers-b-cell-clonogenic-activity-to-the-hiv-1-matrix-protein-p17
#10
Cinzia Giagulli, Pasqualina D'Ursi, Wangxiao He, Simone Zorzan, Francesca Caccuri, Kristen Varney, Alessandro Orro, Stefania Marsico, Benoît Otjacques, Carlo Laudanna, Luciano Milanesi, Riccardo Dolcetti, Simona Fiorentini, Wuyuan Lu, Arnaldo Caruso
Recent data highlight the presence, in HIV-1-seropositive patients with lymphoma, of p17 variants (vp17s) endowed with B-cell clonogenicity, suggesting a role of vp17s in lymphomagenesis. We investigated the mechanisms responsible for the functional disparity on B cells between a wild-type p17 (refp17) and a vp17 named S75X. Here, we show that a single Arginine (R) to Glycine (G) mutation at position 76 in the refp17 backbone (p17R76G), as in the S75X variant, is per se sufficient to confer a B-cell clonogenic potential to the viral protein and modulate, through activation of the PTEN/PI3K/Akt signaling pathway, different molecules involved in apoptosis inhibition (CASP-9, CASP-7, DFF-45, NPM, YWHAZ, Src, PAX2, MAPK8), cell cycle promotion and cancer progression (CDK1, CDK2, CDK8, CHEK1, CHEK2, GSK-3 beta, NPM, PAK1, PP2C-alpha)...
July 26, 2017: Scientific Reports
https://www.readbyqxmd.com/read/28747349/outcomes-associated-with-a-pediatric-clinical-diabetes-network-in-ontario-a-population-based-time-trend-analysis
#11
Meranda Nakhla, Elham Rahme, Marc Simard, Astrid Guttmann
BACKGROUND: The Network of Ontario Pediatric Diabetes Programs was implemented in 2001. The objective of this study was to determine whether implementation of the network was associated with a decrease in the risk of acute diabetes-related complications and a reduction in the socioeconomic and geographic disparities in these outcomes. METHODS: We conducted a population-based time trend analysis of children (< 18 yr) with diabetes using health administrative databases in Ontario from 1996 to 2011...
July 24, 2017: CMAJ Open
https://www.readbyqxmd.com/read/28747321/the-affordable-care-act-reduced-socioeconomic-disparities-in-health-care-access
#12
Kevin Griffith, Leigh Evans, Jacob Bor
The United States has the largest socioeconomic disparities in health care access of any wealthy country. We assessed changes in these disparities in the United States under the Affordable Care Act (ACA). We used survey data for the period 2011-15 from the Behavioral Risk Factor Surveillance System to assess trends in insurance coverage, having a personal doctor, and avoiding medical care due to cost. All analyses were stratified by household income, education level, employment status, and home ownership status...
July 26, 2017: Health Affairs
https://www.readbyqxmd.com/read/28746813/binocular-mechanisms-of-3d-motion-processing
#13
Lawrence K Cormack, Thaddeus B Czuba, Jonas Knöll, Alexander C Huk
The visual system must recover important properties of the external environment if its host is to survive. Because the retinae are effectively twodimensional but the world is three-dimensional (3D), the patterns of stimulation both within and across the eyes must be used to infer the distal stimulus-the environment-in all three dimensions. Moreover, animals and elements in the environment move, which means the input contains rich temporal information. Here, in addition to reviewing the literature, we discuss how and why prior work has focused on purported isolated systems (e...
July 26, 2017: Annual Review of Vision Science
https://www.readbyqxmd.com/read/28746802/leading-by-gaslight-nursing-s-academic-leadership-struggles
#14
EDITORIAL
David R Thompson, Alexander M Clark
What characterizes strong nursing leadership in academia? Not what you might think. Popular mythology may suggest strength and certainty: people who transcend, get their way, and "call" the important decisions (Brown 2014). Yet, historian Archie Brown (2014) analyzing hundreds of leaders over hundreds of years suggests otherwise, with: integrity, relationship building, collegiality, curiosity, willingness to seek disparate views, empathy and energy being far more important (Brown 2014). Stereotypical strength, it transpires, is steadfast weakness...
July 26, 2017: Journal of Advanced Nursing
https://www.readbyqxmd.com/read/28746555/the-color-of-pain-racial-iniquities-in-prenatal-care-and-childbirth-in-brazil
#15
Maria do Carmo Leal, Silvana Granado Nogueira da Gama, Ana Paula Esteves Pereira, Vanessa Eufrauzino Pacheco, Cleber Nascimento do Carmo, Ricardo Ventura Santos
Few studies on the influence of race/color on pregnancy and birthcare experiences have been carried out in Brazil. Additionally, none of the existing studies are of national scope. This study sought to evaluate inequities in prenatal and childbirth care according to race/color using propensity score matching. The data comes from the study Birth in Brazil: National Survey into Labor and Birth, a national population study comprised of interviews and revisions of medical records that included 23,894 women in 2011/2012...
July 24, 2017: Cadernos de Saúde Pública
https://www.readbyqxmd.com/read/28746404/pitx1-determines-characteristic-hindlimb-morphologies-in-cartilage-micromass-culture
#16
Natalie C Butterfield, Chen Qian, Malcolm P O Logan
The shapes of homologous skeletal elements in the vertebrate forelimb and hindlimb are distinct, with each element exquisitely adapted to their divergent functions. Many of the signals and signalling pathways responsible for patterning the developing limb bud are common to both forelimb and hindlimb. How disparate morphologies are generated from common signalling inputs during limb development remains poorly understood. We show that, similar to what has been shown in the chick, characteristic differences in mouse forelimb and hindlimb cartilage morphology are maintained when chondrogenesis proceeds in vitro away from the endogenous limb bud environment...
2017: PloS One
https://www.readbyqxmd.com/read/28746347/is-there-a-correlation-between-socioeconomic-disparity-and-functional-outcome-after-acute-ischemic-stroke
#17
Tian Song, Yuesong Pan, Ruoling Chen, Hao Li, Xingquan Zhao, Liping Liu, Chunxue Wang, Yilong Wang, Yongjun Wang
BACKGROUND: To investigate the impact of low socioeconomic status (SES), indicated by low level of education, occupation and income, on 3 months functional outcome after ischemic stroke. METHODS: We analyzed data from the China National Stroke Registry (CNSR), a multicenter and prospective registry of consecutive patients with acute cerebrovascular events occurred between September 2007 and August 2008. 11226 patients with ischemic stroke had SES and clinical characteristics data collected at baseline and mRS measured as indicator of functional outcome in 3 months follow up...
2017: PloS One
https://www.readbyqxmd.com/read/28745447/commentary-perspectives-on-alcohol-related-gene-and-environment-interplay-in-diverse-populations
#18
Marcia S Scott
BACKGROUND AND OBJECTIVES: Racial/ethnic groups comprise more than 20% of the U.S. population, but many experience disproportionately high risk for alcohol misuse, often resulting in higher rates of alcohol-associated consequences. Completion of mapping the human genome has launched rapidly evolving research methods aimed at improved understanding of genetic contribution to disease. Despite decades of research on the influence of genetic and environmental risks on alcohol use disorders and outcomes, few studies have included racial/ethnic subpopulations in sufficient numbers to allow for proper statistical analysis...
August 2017: American Journal on Addictions
https://www.readbyqxmd.com/read/28745309/a-quantitative-and-efficient-approach-to-select-miru-vntr-loci-based-on-accumulation-of-the-percentage-differences-of-strains-for-discriminating-divergent-mycobacterium-tuberculosis-sublineages
#19
Xin-Ling Pan, Chun-Lei Zhang, Chie Nakajima, Jin Fu, Chang-Xia Shao, Li-Na Zhao, Jia-Yi Cui, Na Jiao, Chang-Long Fan, Yasuhiko Suzuki, Toshio Hattori, Di Li, Hong Ling
Although several optimal mycobacterial interspersed repetitive units-variable number tandem repeat (MIRU-VNTR) loci have been suggested for genotyping homogenous Mycobacterium tuberculosis, including the Beijing genotype, a more efficient and convenient selection strategy for identifying optimal VNTR loci is needed. Here 281 M. tuberculosis isolates were analyzed. Beijing genotype and non-Beijing genotypes were identified, as well as Beijing sublineages, according to single nucleotide polymorphisms. A total of 22 MIRU-VNTR loci were used for genotyping...
July 26, 2017: Emerging Microbes & Infections
https://www.readbyqxmd.com/read/28744760/development-and-psychometric-evaluation-of-the-autism-stigma-and-knowledge-questionnaire-ask-q
#20
Ashley J Harrison, Laine P Bradshaw, Nilofer C Naqvi, Madison L Paff, Jonathan M Campbell
ASD knowledge deficits contribute to disparities in the timing and quality of ASD services. To address the limitations with existing measures of ASD knowledge, we developed and examined the Autism Stigma and Knowledge Questionnaire (ASK-Q), which comprehensively assesses multiple subdomains of ASD knowledge while maintaining strong psychometric support and cross-cultural utility. ASK-Q items derived from the published research are organized into four subscales: (i) diagnosis, (ii) etiology, (iii) treatment, and (iv) stigma...
July 25, 2017: Journal of Autism and Developmental Disorders
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