Siân P Cartland, Christopher P Stanley, Christina Bursill, Freda Passam, Gemma A Figtree, Sanjay Patel, Jacky Loa, Jonathan Golledge, David A Robinson, Sarah J Aitken, Mary M Kavurma
Peripheral artery disease (PAD) is caused by blocked arteries due to atherosclerosis and/or thrombosis which reduce blood flow to the lower limbs. It results in major morbidity, including ischemic limb, claudication, and amputation, with patients also suffering a heightened risk of heart attack, stroke, and death. Recent studies suggest women have a higher prevalence of PAD than men, and with worse outcomes after intervention. In addition to a potential unconscious bias faced by women with PAD in the health system, with underdiagnosis, and lower rates of guideline-based therapy, fundamental biological differences between men and women may be important...
December 13, 2023: International Journal of Molecular Sciences